Amino acid dipepetide frequency for Salvia hispanica RNA virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.535AlaAla: 12.535 ± 5.794
1.393AlaCys: 1.393 ± 0.644
8.357AlaAsp: 8.357 ± 3.863
8.357AlaGlu: 8.357 ± 1.099
6.267AlaPhe: 6.267 ± 0.824
6.267AlaGly: 6.267 ± 2.206
0.696AlaHis: 0.696 ± 0.369
0.0AlaIle: 0.0 ± 0.0
2.786AlaLys: 2.786 ± 0.094
7.66AlaLeu: 7.66 ± 1.296
4.875AlaMet: 4.875 ± 1.562
2.786AlaAsn: 2.786 ± 1.288
5.571AlaPro: 5.571 ± 2.575
6.267AlaGln: 6.267 ± 0.824
6.267AlaArg: 6.267 ± 0.824
4.875AlaSer: 4.875 ± 1.562
6.964AlaThr: 6.964 ± 0.455
4.178AlaVal: 4.178 ± 0.55
4.178AlaTrp: 4.178 ± 1.931
2.786AlaTyr: 2.786 ± 0.094
0.0AlaXaa: 0.0 ± 0.0
Cys
2.089CysAla: 2.089 ± 0.275
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.696CysPhe: 0.696 ± 0.369
0.696CysGly: 0.696 ± 0.369
1.393CysHis: 1.393 ± 0.644
0.696CysIle: 0.696 ± 0.369
0.0CysLys: 0.0 ± 0.0
1.393CysLeu: 1.393 ± 0.738
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
1.393CysGln: 1.393 ± 0.644
0.696CysArg: 0.696 ± 0.369
0.696CysSer: 0.696 ± 0.369
1.393CysThr: 1.393 ± 0.644
0.696CysVal: 0.696 ± 0.369
0.0CysTrp: 0.0 ± 0.0
0.696CysTyr: 0.696 ± 0.369
0.0CysXaa: 0.0 ± 0.0
Asp
5.571AspAla: 5.571 ± 0.189
0.0AspCys: 0.0 ± 0.0
5.571AspAsp: 5.571 ± 1.571
3.482AspGlu: 3.482 ± 0.463
3.482AspPhe: 3.482 ± 0.463
0.696AspGly: 0.696 ± 0.369
2.089AspHis: 2.089 ± 1.657
7.66AspIle: 7.66 ± 1.468
0.696AspLys: 0.696 ± 0.369
8.357AspLeu: 8.357 ± 1.099
2.089AspMet: 2.089 ± 1.107
1.393AspAsn: 1.393 ± 0.738
5.571AspPro: 5.571 ± 1.193
1.393AspGln: 1.393 ± 0.644
2.089AspArg: 2.089 ± 1.107
3.482AspSer: 3.482 ± 0.463
2.089AspThr: 2.089 ± 0.275
3.482AspVal: 3.482 ± 0.919
2.089AspTrp: 2.089 ± 1.107
0.696AspTyr: 0.696 ± 0.369
0.0AspXaa: 0.0 ± 0.0
Glu
16.713GluAla: 16.713 ± 3.58
0.696GluCys: 0.696 ± 0.369
5.571GluAsp: 5.571 ± 0.189
5.571GluGlu: 5.571 ± 0.189
0.0GluPhe: 0.0 ± 0.0
8.357GluGly: 8.357 ± 2.481
1.393GluHis: 1.393 ± 0.644
2.786GluIle: 2.786 ± 1.288
3.482GluLys: 3.482 ± 0.463
2.786GluLeu: 2.786 ± 0.094
2.089GluMet: 2.089 ± 0.826
3.482GluAsn: 3.482 ± 0.919
0.696GluPro: 0.696 ± 0.369
0.696GluGln: 0.696 ± 0.369
3.482GluArg: 3.482 ± 0.919
3.482GluSer: 3.482 ± 1.845
2.786GluThr: 2.786 ± 0.094
1.393GluVal: 1.393 ± 0.738
1.393GluTrp: 1.393 ± 0.738
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.393PheAla: 1.393 ± 0.644
2.089PheCys: 2.089 ± 0.275
1.393PheAsp: 1.393 ± 0.738
4.875PheGlu: 4.875 ± 1.202
0.0PhePhe: 0.0 ± 0.0
2.786PheGly: 2.786 ± 0.094
0.696PheHis: 0.696 ± 0.369
5.571PheIle: 5.571 ± 1.193
3.482PheLys: 3.482 ± 0.463
3.482PheLeu: 3.482 ± 1.845
1.393PheMet: 1.393 ± 0.738
1.393PheAsn: 1.393 ± 0.738
2.786PhePro: 2.786 ± 0.094
0.696PheGln: 0.696 ± 0.369
4.178PheArg: 4.178 ± 0.832
0.696PheSer: 0.696 ± 0.369
2.786PheThr: 2.786 ± 0.094
2.786PheVal: 2.786 ± 1.476
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
0.0GlyAla: 0.0 ± 0.0
0.0GlyCys: 0.0 ± 0.0
3.482GlyAsp: 3.482 ± 0.919
6.267GlyGlu: 6.267 ± 2.206
0.696GlyPhe: 0.696 ± 0.369
11.142GlyGly: 11.142 ± 1.005
2.089GlyHis: 2.089 ± 0.275
4.875GlyIle: 4.875 ± 2.583
0.0GlyLys: 0.0 ± 0.0
6.267GlyLeu: 6.267 ± 0.558
2.786GlyMet: 2.786 ± 0.094
5.571GlyAsn: 5.571 ± 1.193
3.482GlyPro: 3.482 ± 0.463
1.393GlyGln: 1.393 ± 0.644
3.482GlyArg: 3.482 ± 0.463
6.964GlySer: 6.964 ± 1.837
2.786GlyThr: 2.786 ± 0.094
2.089GlyVal: 2.089 ± 1.107
1.393GlyTrp: 1.393 ± 0.738
1.393GlyTyr: 1.393 ± 0.738
0.0GlyXaa: 0.0 ± 0.0
His
2.089HisAla: 2.089 ± 0.275
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.696HisGlu: 0.696 ± 0.369
0.696HisPhe: 0.696 ± 0.369
0.696HisGly: 0.696 ± 0.369
1.393HisHis: 1.393 ± 0.738
0.0HisIle: 0.0 ± 0.0
0.696HisLys: 0.696 ± 0.369
1.393HisLeu: 1.393 ± 0.738
0.0HisMet: 0.0 ± 0.0
1.393HisAsn: 1.393 ± 0.738
2.089HisPro: 2.089 ± 0.275
2.089HisGln: 2.089 ± 0.275
5.571HisArg: 5.571 ± 0.189
0.696HisSer: 0.696 ± 0.369
1.393HisThr: 1.393 ± 0.644
2.089HisVal: 2.089 ± 0.275
0.0HisTrp: 0.0 ± 0.0
0.696HisTyr: 0.696 ± 0.369
0.0HisXaa: 0.0 ± 0.0
Ile
5.571IleAla: 5.571 ± 1.193
0.0IleCys: 0.0 ± 0.0
4.178IleAsp: 4.178 ± 0.55
3.482IleGlu: 3.482 ± 0.463
2.089IlePhe: 2.089 ± 1.107
1.393IleGly: 1.393 ± 0.738
0.696IleHis: 0.696 ± 0.369
2.786IleIle: 2.786 ± 0.094
5.571IleLys: 5.571 ± 1.193
0.696IleLeu: 0.696 ± 0.369
2.089IleMet: 2.089 ± 0.275
0.696IleAsn: 0.696 ± 0.369
2.089IlePro: 2.089 ± 1.107
0.0IleGln: 0.0 ± 0.0
4.875IleArg: 4.875 ± 1.562
3.482IleSer: 3.482 ± 0.463
4.875IleThr: 4.875 ± 0.18
0.696IleVal: 0.696 ± 0.369
0.0IleTrp: 0.0 ± 0.0
1.393IleTyr: 1.393 ± 0.738
0.0IleXaa: 0.0 ± 0.0
Lys
6.267LysAla: 6.267 ± 0.558
0.696LysCys: 0.696 ± 0.369
1.393LysAsp: 1.393 ± 0.738
1.393LysGlu: 1.393 ± 0.738
4.875LysPhe: 4.875 ± 0.18
6.964LysGly: 6.964 ± 2.309
0.696LysHis: 0.696 ± 0.369
0.0LysIle: 0.0 ± 0.0
4.875LysLys: 4.875 ± 1.202
5.571LysLeu: 5.571 ± 2.953
0.696LysMet: 0.696 ± 0.369
1.393LysAsn: 1.393 ± 0.738
2.089LysPro: 2.089 ± 1.107
0.0LysGln: 0.0 ± 0.0
9.053LysArg: 9.053 ± 0.73
4.178LysSer: 4.178 ± 0.55
1.393LysThr: 1.393 ± 0.644
4.875LysVal: 4.875 ± 0.18
0.0LysTrp: 0.0 ± 0.0
1.393LysTyr: 1.393 ± 0.738
0.0LysXaa: 0.0 ± 0.0
Leu
11.838LeuAla: 11.838 ± 3.4
0.0LeuCys: 0.0 ± 0.0
6.964LeuAsp: 6.964 ± 2.309
4.178LeuGlu: 4.178 ± 0.832
1.393LeuPhe: 1.393 ± 0.738
4.875LeuGly: 4.875 ± 1.562
2.089LeuHis: 2.089 ± 1.107
1.393LeuIle: 1.393 ± 0.738
6.964LeuLys: 6.964 ± 0.927
11.142LeuLeu: 11.142 ± 1.759
1.393LeuMet: 1.393 ± 0.738
2.786LeuAsn: 2.786 ± 1.476
2.786LeuPro: 2.786 ± 1.476
2.786LeuGln: 2.786 ± 1.288
4.178LeuArg: 4.178 ± 0.832
4.178LeuSer: 4.178 ± 0.832
6.964LeuThr: 6.964 ± 0.927
3.482LeuVal: 3.482 ± 0.919
2.089LeuTrp: 2.089 ± 1.107
3.482LeuTyr: 3.482 ± 0.463
0.0LeuXaa: 0.0 ± 0.0
Met
2.786MetAla: 2.786 ± 1.288
0.0MetCys: 0.0 ± 0.0
2.089MetAsp: 2.089 ± 0.275
2.786MetGlu: 2.786 ± 0.094
2.089MetPhe: 2.089 ± 0.275
0.696MetGly: 0.696 ± 1.013
0.696MetHis: 0.696 ± 0.369
2.089MetIle: 2.089 ± 0.275
1.393MetLys: 1.393 ± 0.738
4.875MetLeu: 4.875 ± 0.18
1.393MetMet: 1.393 ± 0.738
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.696MetGln: 0.696 ± 0.369
0.696MetArg: 0.696 ± 0.369
0.0MetSer: 0.0 ± 0.0
0.696MetThr: 0.696 ± 0.369
3.482MetVal: 3.482 ± 1.845
0.0MetTrp: 0.0 ± 0.0
0.696MetTyr: 0.696 ± 0.369
0.0MetXaa: 0.0 ± 0.0
Asn
2.089AsnAla: 2.089 ± 0.275
0.0AsnCys: 0.0 ± 0.0
2.786AsnAsp: 2.786 ± 0.094
2.089AsnGlu: 2.089 ± 0.275
0.696AsnPhe: 0.696 ± 0.369
1.393AsnGly: 1.393 ± 0.738
2.089AsnHis: 2.089 ± 1.107
2.089AsnIle: 2.089 ± 1.657
2.786AsnLys: 2.786 ± 0.094
2.089AsnLeu: 2.089 ± 1.107
0.696AsnMet: 0.696 ± 0.369
2.089AsnAsn: 2.089 ± 1.107
3.482AsnPro: 3.482 ± 0.919
0.696AsnGln: 0.696 ± 1.013
0.696AsnArg: 0.696 ± 1.013
0.0AsnSer: 0.0 ± 0.0
5.571AsnThr: 5.571 ± 1.193
1.393AsnVal: 1.393 ± 0.738
0.696AsnTrp: 0.696 ± 0.369
3.482AsnTyr: 3.482 ± 0.919
0.0AsnXaa: 0.0 ± 0.0
Pro
2.089ProAla: 2.089 ± 1.107
0.696ProCys: 0.696 ± 0.369
0.696ProAsp: 0.696 ± 1.013
4.875ProGlu: 4.875 ± 0.18
4.178ProPhe: 4.178 ± 2.214
4.178ProGly: 4.178 ± 0.832
0.0ProHis: 0.0 ± 0.0
1.393ProIle: 1.393 ± 0.738
2.089ProLys: 2.089 ± 1.107
2.786ProLeu: 2.786 ± 0.094
2.786ProMet: 2.786 ± 0.094
2.089ProAsn: 2.089 ± 1.657
6.267ProPro: 6.267 ± 3.588
1.393ProGln: 1.393 ± 0.644
3.482ProArg: 3.482 ± 2.301
2.786ProSer: 2.786 ± 0.094
4.178ProThr: 4.178 ± 0.832
4.875ProVal: 4.875 ± 1.562
0.0ProTrp: 0.0 ± 0.0
0.696ProTyr: 0.696 ± 0.369
0.0ProXaa: 0.0 ± 0.0
Gln
1.393GlnAla: 1.393 ± 0.644
2.089GlnCys: 2.089 ± 0.275
2.786GlnAsp: 2.786 ± 1.288
1.393GlnGlu: 1.393 ± 2.026
2.786GlnPhe: 2.786 ± 0.094
2.089GlnGly: 2.089 ± 1.657
0.0GlnHis: 0.0 ± 0.0
1.393GlnIle: 1.393 ± 0.644
0.0GlnLys: 0.0 ± 0.0
4.875GlnLeu: 4.875 ± 1.562
1.393GlnMet: 1.393 ± 0.644
0.696GlnAsn: 0.696 ± 1.013
0.696GlnPro: 0.696 ± 0.369
5.571GlnGln: 5.571 ± 1.193
3.482GlnArg: 3.482 ± 0.919
0.0GlnSer: 0.0 ± 0.0
0.696GlnThr: 0.696 ± 0.369
2.089GlnVal: 2.089 ± 0.275
1.393GlnTrp: 1.393 ± 0.738
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
13.928ArgAla: 13.928 ± 6.438
0.696ArgCys: 0.696 ± 0.369
1.393ArgAsp: 1.393 ± 0.738
4.875ArgGlu: 4.875 ± 0.18
3.482ArgPhe: 3.482 ± 0.463
4.178ArgGly: 4.178 ± 0.55
2.089ArgHis: 2.089 ± 0.275
2.089ArgIle: 2.089 ± 0.275
4.875ArgLys: 4.875 ± 0.18
2.089ArgLeu: 2.089 ± 1.107
1.393ArgMet: 1.393 ± 0.738
4.178ArgAsn: 4.178 ± 0.55
2.786ArgPro: 2.786 ± 1.476
2.089ArgGln: 2.089 ± 0.275
13.928ArgArg: 13.928 ± 6.438
2.786ArgSer: 2.786 ± 1.476
4.178ArgThr: 4.178 ± 0.55
4.875ArgVal: 4.875 ± 0.18
0.696ArgTrp: 0.696 ± 0.369
1.393ArgTyr: 1.393 ± 0.738
0.0ArgXaa: 0.0 ± 0.0
Ser
6.267SerAla: 6.267 ± 2.206
2.089SerCys: 2.089 ± 1.107
4.178SerAsp: 4.178 ± 2.214
1.393SerGlu: 1.393 ± 0.644
3.482SerPhe: 3.482 ± 1.845
3.482SerGly: 3.482 ± 0.463
0.696SerHis: 0.696 ± 0.369
0.696SerIle: 0.696 ± 0.369
6.267SerLys: 6.267 ± 3.322
2.089SerLeu: 2.089 ± 1.107
0.696SerMet: 0.696 ± 0.308
1.393SerAsn: 1.393 ± 0.644
4.178SerPro: 4.178 ± 1.931
1.393SerGln: 1.393 ± 0.644
4.178SerArg: 4.178 ± 0.55
5.571SerSer: 5.571 ± 1.571
0.696SerThr: 0.696 ± 0.369
2.089SerVal: 2.089 ± 0.275
1.393SerTrp: 1.393 ± 0.738
0.696SerTyr: 0.696 ± 0.369
0.0SerXaa: 0.0 ± 0.0
Thr
6.267ThrAla: 6.267 ± 0.824
1.393ThrCys: 1.393 ± 0.644
4.875ThrAsp: 4.875 ± 0.18
6.964ThrGlu: 6.964 ± 3.219
3.482ThrPhe: 3.482 ± 0.919
2.786ThrGly: 2.786 ± 1.476
2.089ThrHis: 2.089 ± 1.107
2.089ThrIle: 2.089 ± 1.107
2.089ThrLys: 2.089 ± 1.107
5.571ThrLeu: 5.571 ± 0.189
0.0ThrMet: 0.0 ± 0.0
1.393ThrAsn: 1.393 ± 0.644
1.393ThrPro: 1.393 ± 0.644
2.786ThrGln: 2.786 ± 1.288
2.089ThrArg: 2.089 ± 0.275
6.267ThrSer: 6.267 ± 1.94
3.482ThrThr: 3.482 ± 0.919
2.089ThrVal: 2.089 ± 1.107
2.089ThrTrp: 2.089 ± 0.275
0.696ThrTyr: 0.696 ± 0.369
0.0ThrXaa: 0.0 ± 0.0
Val
1.393ValAla: 1.393 ± 0.644
0.0ValCys: 0.0 ± 0.0
4.178ValAsp: 4.178 ± 0.832
3.482ValGlu: 3.482 ± 0.919
0.696ValPhe: 0.696 ± 0.369
2.089ValGly: 2.089 ± 1.107
2.089ValHis: 2.089 ± 0.275
5.571ValIle: 5.571 ± 0.189
6.267ValLys: 6.267 ± 0.824
5.571ValLeu: 5.571 ± 1.193
0.696ValMet: 0.696 ± 0.369
2.089ValAsn: 2.089 ± 1.107
4.875ValPro: 4.875 ± 1.202
3.482ValGln: 3.482 ± 2.301
2.089ValArg: 2.089 ± 1.107
0.696ValSer: 0.696 ± 0.369
3.482ValThr: 3.482 ± 1.845
2.786ValVal: 2.786 ± 0.094
1.393ValTrp: 1.393 ± 0.738
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.393TrpAla: 1.393 ± 0.738
0.0TrpCys: 0.0 ± 0.0
0.696TrpAsp: 0.696 ± 0.369
0.0TrpGlu: 0.0 ± 0.0
0.696TrpPhe: 0.696 ± 0.369
1.393TrpGly: 1.393 ± 0.738
0.0TrpHis: 0.0 ± 0.0
0.696TrpIle: 0.696 ± 0.369
3.482TrpLys: 3.482 ± 1.845
2.089TrpLeu: 2.089 ± 0.275
0.0TrpMet: 0.0 ± 0.0
1.393TrpAsn: 1.393 ± 0.644
0.696TrpPro: 0.696 ± 0.369
0.0TrpGln: 0.0 ± 0.0
1.393TrpArg: 1.393 ± 0.738
0.0TrpSer: 0.0 ± 0.0
3.482TrpThr: 3.482 ± 0.919
2.089TrpVal: 2.089 ± 1.107
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.393TyrAla: 1.393 ± 0.738
0.696TyrCys: 0.696 ± 0.369
1.393TyrAsp: 1.393 ± 0.644
1.393TyrGlu: 1.393 ± 0.738
0.696TyrPhe: 0.696 ± 0.369
0.0TyrGly: 0.0 ± 0.0
0.696TyrHis: 0.696 ± 0.369
2.786TyrIle: 2.786 ± 1.476
0.0TyrLys: 0.0 ± 0.0
4.178TyrLeu: 4.178 ± 0.55
0.0TyrMet: 0.0 ± 0.0
0.696TyrAsn: 0.696 ± 0.369
0.0TyrPro: 0.0 ± 0.0
0.0TyrGln: 0.0 ± 0.0
2.089TyrArg: 2.089 ± 1.107
2.089TyrSer: 2.089 ± 1.107
0.0TyrThr: 0.0 ± 0.0
1.393TyrVal: 1.393 ± 0.644
0.696TyrTrp: 0.696 ± 0.369
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1437 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski