Amino acid dipepetide frequency for Rice tungro bacilliform virus (isolate Philippines) (RTBV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.265AlaAla: 1.265 ± 1.206
0.0AlaCys: 0.0 ± 0.0
2.53AlaAsp: 2.53 ± 2.529
1.265AlaGlu: 1.265 ± 0.991
1.265AlaPhe: 1.265 ± 0.706
3.794AlaGly: 3.794 ± 3.681
0.843AlaHis: 0.843 ± 0.562
3.373AlaIle: 3.373 ± 1.3
3.373AlaLys: 3.373 ± 1.883
4.637AlaLeu: 4.637 ± 2.396
1.265AlaMet: 1.265 ± 0.948
1.686AlaAsn: 1.686 ± 0.941
1.686AlaPro: 1.686 ± 1.168
1.265AlaGln: 1.265 ± 0.486
3.794AlaArg: 3.794 ± 0.82
4.637AlaSer: 4.637 ± 1.957
1.265AlaThr: 1.265 ± 0.991
2.53AlaVal: 2.53 ± 1.109
0.843AlaTrp: 0.843 ± 1.424
2.53AlaTyr: 2.53 ± 1.412
0.0AlaXaa: 0.0 ± 0.0
Cys
0.843CysAla: 0.843 ± 0.471
0.0CysCys: 0.0 ± 0.0
0.422CysAsp: 0.422 ± 0.235
2.951CysGlu: 2.951 ± 1.579
0.422CysPhe: 0.422 ± 0.712
0.422CysGly: 0.422 ± 0.235
0.0CysHis: 0.0 ± 0.0
0.422CysIle: 0.422 ± 0.235
1.265CysLys: 1.265 ± 0.706
0.422CysLeu: 0.422 ± 0.235
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.686CysPro: 1.686 ± 0.941
0.422CysGln: 0.422 ± 0.235
1.265CysArg: 1.265 ± 0.706
1.265CysSer: 1.265 ± 0.706
0.422CysThr: 0.422 ± 0.712
0.422CysVal: 0.422 ± 0.235
0.0CysTrp: 0.0 ± 0.0
1.265CysTyr: 1.265 ± 0.821
0.0CysXaa: 0.0 ± 0.0
Asp
0.422AspAla: 0.422 ± 0.235
0.843AspCys: 0.843 ± 0.562
4.216AspAsp: 4.216 ± 2.353
4.637AspGlu: 4.637 ± 1.481
2.53AspPhe: 2.53 ± 1.412
2.951AspGly: 2.951 ± 1.011
0.422AspHis: 0.422 ± 0.712
4.216AspIle: 4.216 ± 1.666
5.902AspLys: 5.902 ± 1.962
7.167AspLeu: 7.167 ± 3.687
1.686AspMet: 1.686 ± 0.941
4.216AspAsn: 4.216 ± 1.32
2.108AspPro: 2.108 ± 1.177
2.108AspGln: 2.108 ± 1.024
1.686AspArg: 1.686 ± 0.941
4.216AspSer: 4.216 ± 1.789
2.108AspThr: 2.108 ± 1.61
1.265AspVal: 1.265 ± 1.206
2.108AspTrp: 2.108 ± 1.177
4.637AspTyr: 4.637 ± 1.551
0.0AspXaa: 0.0 ± 0.0
Glu
6.745GluAla: 6.745 ± 2.228
0.0GluCys: 0.0 ± 0.0
7.589GluAsp: 7.589 ± 1.562
5.902GluGlu: 5.902 ± 1.207
2.951GluPhe: 2.951 ± 1.465
4.216GluGly: 4.216 ± 2.048
3.794GluHis: 3.794 ± 1.137
8.853GluIle: 8.853 ± 1.61
8.853GluLys: 8.853 ± 5.647
5.902GluLeu: 5.902 ± 1.153
1.265GluMet: 1.265 ± 0.486
5.481GluAsn: 5.481 ± 1.004
1.265GluPro: 1.265 ± 2.136
2.951GluGln: 2.951 ± 2.538
5.481GluArg: 5.481 ± 2.41
6.324GluSer: 6.324 ± 1.347
5.059GluThr: 5.059 ± 1.624
5.902GluVal: 5.902 ± 1.86
2.108GluTrp: 2.108 ± 1.024
2.53GluTyr: 2.53 ± 0.971
0.0GluXaa: 0.0 ± 0.0
Phe
1.686PheAla: 1.686 ± 0.941
0.843PheCys: 0.843 ± 0.562
3.373PheAsp: 3.373 ± 1.379
2.53PheGlu: 2.53 ± 1.045
0.843PhePhe: 0.843 ± 0.562
2.951PheGly: 2.951 ± 1.011
1.265PheHis: 1.265 ± 0.991
2.951PheIle: 2.951 ± 0.974
2.53PheLys: 2.53 ± 2.529
5.059PheLeu: 5.059 ± 2.1
0.843PheMet: 0.843 ± 0.471
3.373PheAsn: 3.373 ± 1.24
0.843PhePro: 0.843 ± 0.562
1.265PheGln: 1.265 ± 0.706
0.843PheArg: 0.843 ± 0.562
1.686PheSer: 1.686 ± 0.516
2.951PheThr: 2.951 ± 1.379
0.843PheVal: 0.843 ± 0.471
0.0PheTrp: 0.0 ± 0.0
2.951PheTyr: 2.951 ± 0.577
0.0PheXaa: 0.0 ± 0.0
Gly
0.843GlyAla: 0.843 ± 1.287
1.265GlyCys: 1.265 ± 0.706
2.951GlyAsp: 2.951 ± 0.974
2.53GlyGlu: 2.53 ± 0.971
2.108GlyPhe: 2.108 ± 1.024
1.686GlyGly: 1.686 ± 0.516
0.422GlyHis: 0.422 ± 0.235
4.637GlyIle: 4.637 ± 1.957
4.637GlyLys: 4.637 ± 1.528
4.637GlyLeu: 4.637 ± 1.479
0.843GlyMet: 0.843 ± 0.471
2.951GlyAsn: 2.951 ± 1.011
0.422GlyPro: 0.422 ± 0.235
1.265GlyGln: 1.265 ± 1.206
1.265GlyArg: 1.265 ± 0.706
2.951GlySer: 2.951 ± 2.408
0.843GlyThr: 0.843 ± 0.471
2.108GlyVal: 2.108 ± 1.024
0.843GlyTrp: 0.843 ± 0.471
3.373GlyTyr: 3.373 ± 1.501
0.0GlyXaa: 0.0 ± 0.0
His
0.422HisAla: 0.422 ± 0.712
0.0HisCys: 0.0 ± 0.0
0.843HisAsp: 0.843 ± 0.562
1.265HisGlu: 1.265 ± 0.706
0.0HisPhe: 0.0 ± 0.0
1.265HisGly: 1.265 ± 0.486
0.422HisHis: 0.422 ± 0.235
2.951HisIle: 2.951 ± 1.579
1.265HisLys: 1.265 ± 0.706
2.951HisLeu: 2.951 ± 0.974
0.422HisMet: 0.422 ± 0.235
0.843HisAsn: 0.843 ± 0.471
0.0HisPro: 0.0 ± 0.0
0.422HisGln: 0.422 ± 0.974
2.53HisArg: 2.53 ± 0.812
2.53HisSer: 2.53 ± 1.641
1.686HisThr: 1.686 ± 0.808
0.422HisVal: 0.422 ± 0.712
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.637IleAla: 4.637 ± 0.724
1.265IleCys: 1.265 ± 0.706
4.216IleAsp: 4.216 ± 1.156
9.275IleGlu: 9.275 ± 1.631
2.951IlePhe: 2.951 ± 0.974
5.902IleGly: 5.902 ± 2.581
1.265IleHis: 1.265 ± 1.261
6.324IleIle: 6.324 ± 1.457
12.648IleLys: 12.648 ± 2.231
4.637IleLeu: 4.637 ± 1.214
1.265IleMet: 1.265 ± 0.706
4.216IleAsn: 4.216 ± 0.878
3.794IlePro: 3.794 ± 1.442
2.951IleGln: 2.951 ± 1.205
1.686IleArg: 1.686 ± 0.941
5.059IleSer: 5.059 ± 2.1
4.216IleThr: 4.216 ± 1.666
4.637IleVal: 4.637 ± 1.528
0.0IleTrp: 0.0 ± 0.0
2.951IleTyr: 2.951 ± 1.579
0.0IleXaa: 0.0 ± 0.0
Lys
4.637LysAla: 4.637 ± 1.528
1.265LysCys: 1.265 ± 0.706
7.589LysAsp: 7.589 ± 1.069
10.961LysGlu: 10.961 ± 2.007
4.637LysPhe: 4.637 ± 2.405
4.216LysGly: 4.216 ± 2.334
1.686LysHis: 1.686 ± 2.801
8.853LysIle: 8.853 ± 2.122
10.54LysLys: 10.54 ± 1.897
8.853LysLeu: 8.853 ± 1.61
2.108LysMet: 2.108 ± 1.177
9.696LysAsn: 9.696 ± 0.711
3.794LysPro: 3.794 ± 0.82
3.794LysGln: 3.794 ± 2.509
4.637LysArg: 4.637 ± 0.874
4.637LysSer: 4.637 ± 0.86
6.745LysThr: 6.745 ± 2.866
3.373LysVal: 3.373 ± 1.501
0.0LysTrp: 0.0 ± 0.0
4.216LysTyr: 4.216 ± 1.646
0.0LysXaa: 0.0 ± 0.0
Leu
3.794LeuAla: 3.794 ± 1.285
0.422LeuCys: 0.422 ± 0.712
5.481LeuAsp: 5.481 ± 2.123
9.696LeuGlu: 9.696 ± 5.861
2.108LeuPhe: 2.108 ± 1.024
3.373LeuGly: 3.373 ± 1.883
1.686LeuHis: 1.686 ± 0.516
6.324LeuIle: 6.324 ± 2.177
9.275LeuLys: 9.275 ± 3.007
5.481LeuLeu: 5.481 ± 2.802
0.0LeuMet: 0.0 ± 0.0
5.059LeuAsn: 5.059 ± 1.419
2.108LeuPro: 2.108 ± 1.167
5.059LeuGln: 5.059 ± 2.059
4.637LeuArg: 4.637 ± 3.194
5.059LeuSer: 5.059 ± 1.732
2.53LeuThr: 2.53 ± 1.066
3.794LeuVal: 3.794 ± 0.956
0.0LeuTrp: 0.0 ± 0.0
5.059LeuTyr: 5.059 ± 1.382
0.0LeuXaa: 0.0 ± 0.0
Met
2.108MetAla: 2.108 ± 1.177
0.0MetCys: 0.0 ± 0.0
1.686MetAsp: 1.686 ± 0.516
0.843MetGlu: 0.843 ± 0.562
1.265MetPhe: 1.265 ± 0.706
0.0MetGly: 0.0 ± 0.0
0.843MetHis: 0.843 ± 0.471
1.686MetIle: 1.686 ± 0.941
1.265MetLys: 1.265 ± 0.486
0.0MetLeu: 0.0 ± 0.0
0.422MetMet: 0.422 ± 0.235
0.843MetAsn: 0.843 ± 0.562
0.0MetPro: 0.0 ± 0.0
1.686MetGln: 1.686 ± 0.941
1.686MetArg: 1.686 ± 0.516
1.686MetSer: 1.686 ± 1.911
0.0MetThr: 0.0 ± 0.0
1.686MetVal: 1.686 ± 0.516
0.422MetTrp: 0.422 ± 0.235
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.686AsnAla: 1.686 ± 0.516
0.422AsnCys: 0.422 ± 0.235
0.843AsnAsp: 0.843 ± 0.471
5.059AsnGlu: 5.059 ± 1.548
5.059AsnPhe: 5.059 ± 0.851
0.843AsnGly: 0.843 ± 0.471
1.265AsnHis: 1.265 ± 0.706
5.902AsnIle: 5.902 ± 2.195
5.902AsnLys: 5.902 ± 1.207
6.745AsnLeu: 6.745 ± 3.506
0.843AsnMet: 0.843 ± 0.562
2.951AsnAsn: 2.951 ± 1.01
2.108AsnPro: 2.108 ± 1.177
3.373AsnGln: 3.373 ± 1.387
2.108AsnArg: 2.108 ± 1.177
2.951AsnSer: 2.951 ± 1.465
3.794AsnThr: 3.794 ± 2.729
2.53AsnVal: 2.53 ± 0.812
0.843AsnTrp: 0.843 ± 1.287
3.794AsnTyr: 3.794 ± 1.442
0.0AsnXaa: 0.0 ± 0.0
Pro
1.686ProAla: 1.686 ± 2.574
0.422ProCys: 0.422 ± 0.235
2.108ProAsp: 2.108 ± 0.638
2.951ProGlu: 2.951 ± 1.579
2.108ProPhe: 2.108 ± 0.638
0.422ProGly: 0.422 ± 0.712
1.265ProHis: 1.265 ± 0.706
2.53ProIle: 2.53 ± 2.523
2.53ProLys: 2.53 ± 2.149
2.951ProLeu: 2.951 ± 1.011
0.422ProMet: 0.422 ± 0.235
1.686ProAsn: 1.686 ± 0.941
1.686ProPro: 1.686 ± 1.303
1.265ProGln: 1.265 ± 0.706
1.686ProArg: 1.686 ± 1.124
0.843ProSer: 0.843 ± 0.471
6.324ProThr: 6.324 ± 2.438
0.422ProVal: 0.422 ± 0.712
0.0ProTrp: 0.0 ± 0.0
1.265ProTyr: 1.265 ± 1.261
0.0ProXaa: 0.0 ± 0.0
Gln
2.53GlnAla: 2.53 ± 1.641
0.0GlnCys: 0.0 ± 0.0
2.951GlnAsp: 2.951 ± 0.974
3.794GlnGlu: 3.794 ± 1.339
1.265GlnPhe: 1.265 ± 0.821
2.108GlnGly: 2.108 ± 1.167
0.0GlnHis: 0.0 ± 0.0
2.53GlnIle: 2.53 ± 0.812
3.794GlnLys: 3.794 ± 2.208
3.373GlnLeu: 3.373 ± 1.955
0.422GlnMet: 0.422 ± 0.712
3.373GlnAsn: 3.373 ± 3.511
1.686GlnPro: 1.686 ± 0.941
1.686GlnGln: 1.686 ± 0.808
1.686GlnArg: 1.686 ± 0.941
1.686GlnSer: 1.686 ± 0.516
2.108GlnThr: 2.108 ± 1.177
1.686GlnVal: 1.686 ± 1.813
0.0GlnTrp: 0.0 ± 0.0
0.843GlnTyr: 0.843 ± 1.287
0.0GlnXaa: 0.0 ± 0.0
Arg
2.108ArgAla: 2.108 ± 0.638
1.265ArgCys: 1.265 ± 0.486
1.686ArgAsp: 1.686 ± 0.838
5.902ArgGlu: 5.902 ± 1.518
2.53ArgPhe: 2.53 ± 0.812
1.686ArgGly: 1.686 ± 1.124
0.843ArgHis: 0.843 ± 0.471
2.53ArgIle: 2.53 ± 0.812
4.216ArgLys: 4.216 ± 1.646
3.794ArgLeu: 3.794 ± 1.457
0.843ArgMet: 0.843 ± 0.562
1.265ArgAsn: 1.265 ± 0.706
3.794ArgPro: 3.794 ± 0.82
0.0ArgGln: 0.0 ± 0.0
2.108ArgArg: 2.108 ± 1.177
1.686ArgSer: 1.686 ± 0.516
2.951ArgThr: 2.951 ± 0.577
2.53ArgVal: 2.53 ± 0.971
0.843ArgTrp: 0.843 ± 0.562
0.843ArgTyr: 0.843 ± 0.869
0.0ArgXaa: 0.0 ± 0.0
Ser
2.108SerAla: 2.108 ± 3.967
1.265SerCys: 1.265 ± 0.486
2.951SerAsp: 2.951 ± 1.237
7.167SerGlu: 7.167 ± 1.866
2.108SerPhe: 2.108 ± 0.66
2.108SerGly: 2.108 ± 1.177
2.108SerHis: 2.108 ± 1.024
7.589SerIle: 7.589 ± 1.203
8.01SerLys: 8.01 ± 2.652
5.059SerLeu: 5.059 ± 1.027
0.843SerMet: 0.843 ± 0.562
2.951SerAsn: 2.951 ± 1.01
0.843SerPro: 0.843 ± 1.424
2.108SerGln: 2.108 ± 1.723
3.373SerArg: 3.373 ± 0.766
5.059SerSer: 5.059 ± 2.131
2.951SerThr: 2.951 ± 1.205
1.686SerVal: 1.686 ± 0.941
1.265SerTrp: 1.265 ± 0.486
3.373SerTyr: 3.373 ± 1.032
0.0SerXaa: 0.0 ± 0.0
Thr
2.951ThrAla: 2.951 ± 1.325
2.108ThrCys: 2.108 ± 1.177
2.951ThrAsp: 2.951 ± 1.205
5.059ThrGlu: 5.059 ± 1.548
2.951ThrPhe: 2.951 ± 1.237
2.108ThrGly: 2.108 ± 1.177
1.265ThrHis: 1.265 ± 0.706
3.373ThrIle: 3.373 ± 1.883
5.902ThrLys: 5.902 ± 1.231
2.951ThrLeu: 2.951 ± 2.035
2.53ThrMet: 2.53 ± 0.462
3.373ThrAsn: 3.373 ± 2.249
1.265ThrPro: 1.265 ± 0.486
3.373ThrGln: 3.373 ± 2.953
0.843ThrArg: 0.843 ± 0.471
4.637ThrSer: 4.637 ± 1.523
5.481ThrThr: 5.481 ± 2.914
2.108ThrVal: 2.108 ± 1.499
2.53ThrTrp: 2.53 ± 1.412
1.265ThrTyr: 1.265 ± 0.706
0.0ThrXaa: 0.0 ± 0.0
Val
1.686ValAla: 1.686 ± 0.941
1.686ValCys: 1.686 ± 0.941
2.53ValAsp: 2.53 ± 0.573
5.059ValGlu: 5.059 ± 2.514
1.686ValPhe: 1.686 ± 1.303
1.265ValGly: 1.265 ± 0.706
0.0ValHis: 0.0 ± 0.0
1.265ValIle: 1.265 ± 0.486
7.167ValLys: 7.167 ± 1.84
2.53ValLeu: 2.53 ± 0.971
0.422ValMet: 0.422 ± 0.235
1.265ValAsn: 1.265 ± 1.206
2.951ValPro: 2.951 ± 2.46
0.843ValGln: 0.843 ± 1.287
1.265ValArg: 1.265 ± 0.486
3.794ValSer: 3.794 ± 1.135
2.951ValThr: 2.951 ± 1.011
1.686ValVal: 1.686 ± 1.124
0.422ValTrp: 0.422 ± 0.974
1.686ValTyr: 1.686 ± 1.124
0.0ValXaa: 0.0 ± 0.0
Trp
0.422TrpAla: 0.422 ± 0.712
0.0TrpCys: 0.0 ± 0.0
0.422TrpAsp: 0.422 ± 0.235
2.53TrpGlu: 2.53 ± 0.812
0.0TrpPhe: 0.0 ± 0.0
0.843TrpGly: 0.843 ± 0.869
0.0TrpHis: 0.0 ± 0.0
2.108TrpIle: 2.108 ± 1.024
0.843TrpLys: 0.843 ± 0.471
0.0TrpLeu: 0.0 ± 0.0
0.843TrpMet: 0.843 ± 0.471
1.265TrpAsn: 1.265 ± 0.486
0.422TrpPro: 0.422 ± 0.712
0.422TrpGln: 0.422 ± 0.235
0.0TrpArg: 0.0 ± 0.0
0.422TrpSer: 0.422 ± 0.235
1.265TrpThr: 1.265 ± 0.486
0.843TrpVal: 0.843 ± 1.287
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.686TyrAla: 1.686 ± 1.303
0.843TyrCys: 0.843 ± 0.869
2.108TyrAsp: 2.108 ± 0.638
3.794TyrGlu: 3.794 ± 0.82
0.843TyrPhe: 0.843 ± 0.869
0.422TyrGly: 0.422 ± 0.712
0.843TyrHis: 0.843 ± 0.562
5.481TyrIle: 5.481 ± 1.004
6.324TyrLys: 6.324 ± 1.451
3.794TyrLeu: 3.794 ± 0.675
0.422TyrMet: 0.422 ± 0.712
2.53TyrAsn: 2.53 ± 1.412
2.108TyrPro: 2.108 ± 2.664
1.265TyrGln: 1.265 ± 0.486
0.843TyrArg: 0.843 ± 0.562
3.794TyrSer: 3.794 ± 2.208
3.373TyrThr: 3.373 ± 1.032
1.686TyrVal: 1.686 ± 0.941
0.422TyrTrp: 0.422 ± 0.712
2.108TyrTyr: 2.108 ± 1.819
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (2373 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski