Amino acid dipepetide frequency for Cotton leaf curl Multan virus-[Faisalabad3]

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.346AlaAla: 6.346 ± 2.024
1.813AlaCys: 1.813 ± 1.214
1.813AlaAsp: 1.813 ± 0.736
0.907AlaGlu: 0.907 ± 1.105
0.0AlaPhe: 0.0 ± 0.0
2.72AlaGly: 2.72 ± 1.015
0.907AlaHis: 0.907 ± 0.646
1.813AlaIle: 1.813 ± 1.291
2.72AlaLys: 2.72 ± 1.297
5.44AlaLeu: 5.44 ± 1.647
0.0AlaMet: 0.0 ± 0.0
0.907AlaAsn: 0.907 ± 0.646
2.72AlaPro: 2.72 ± 1.147
5.44AlaGln: 5.44 ± 1.761
4.533AlaArg: 4.533 ± 2.072
5.44AlaSer: 5.44 ± 2.441
2.72AlaThr: 2.72 ± 2.328
1.813AlaVal: 1.813 ± 1.049
1.813AlaTrp: 1.813 ± 0.736
3.626AlaTyr: 3.626 ± 1.448
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.813CysCys: 1.813 ± 2.384
0.0CysAsp: 0.0 ± 0.0
1.813CysGlu: 1.813 ± 1.214
0.907CysPhe: 0.907 ± 1.059
1.813CysGly: 1.813 ± 0.837
0.907CysHis: 0.907 ± 0.744
0.907CysIle: 0.907 ± 0.776
0.907CysLys: 0.907 ± 0.776
0.0CysLeu: 0.0 ± 0.0
0.907CysMet: 0.907 ± 1.192
1.813CysAsn: 1.813 ± 0.837
1.813CysPro: 1.813 ± 2.384
0.0CysGln: 0.0 ± 0.0
1.813CysArg: 1.813 ± 1.166
4.533CysSer: 4.533 ± 1.751
2.72CysThr: 2.72 ± 0.768
0.907CysVal: 0.907 ± 0.776
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.813AspAla: 1.813 ± 1.291
0.0AspCys: 0.0 ± 0.0
1.813AspAsp: 1.813 ± 0.837
3.626AspGlu: 3.626 ± 1.046
1.813AspPhe: 1.813 ± 0.736
1.813AspGly: 1.813 ± 1.291
0.907AspHis: 0.907 ± 0.744
1.813AspIle: 1.813 ± 1.236
2.72AspLys: 2.72 ± 0.967
4.533AspLeu: 4.533 ± 1.882
0.0AspMet: 0.0 ± 0.0
2.72AspAsn: 2.72 ± 1.146
4.533AspPro: 4.533 ± 1.882
2.72AspGln: 2.72 ± 1.199
3.626AspArg: 3.626 ± 1.472
3.626AspSer: 3.626 ± 1.1
2.72AspThr: 2.72 ± 2.268
3.626AspVal: 3.626 ± 2.099
1.813AspTrp: 1.813 ± 0.837
1.813AspTyr: 1.813 ± 1.214
0.0AspXaa: 0.0 ± 0.0
Glu
4.533GluAla: 4.533 ± 2.12
0.907GluCys: 0.907 ± 0.744
1.813GluAsp: 1.813 ± 2.21
6.346GluGlu: 6.346 ± 3.803
3.626GluPhe: 3.626 ± 1.932
2.72GluGly: 2.72 ± 1.147
0.907GluHis: 0.907 ± 1.059
0.907GluIle: 0.907 ± 1.059
0.907GluLys: 0.907 ± 0.646
5.44GluLeu: 5.44 ± 2.709
0.0GluMet: 0.0 ± 0.0
2.72GluAsn: 2.72 ± 2.328
3.626GluPro: 3.626 ± 1.168
2.72GluGln: 2.72 ± 1.389
0.0GluArg: 0.0 ± 0.0
5.44GluSer: 5.44 ± 2.273
0.907GluThr: 0.907 ± 0.646
4.533GluVal: 4.533 ± 1.591
1.813GluTrp: 1.813 ± 0.837
0.907GluTyr: 0.907 ± 0.744
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.907PheCys: 0.907 ± 0.776
1.813PheAsp: 1.813 ± 0.736
1.813PheGlu: 1.813 ± 0.736
1.813PhePhe: 1.813 ± 0.736
2.72PheGly: 2.72 ± 1.577
1.813PheHis: 1.813 ± 1.291
0.907PheIle: 0.907 ± 0.646
3.626PheLys: 3.626 ± 3.033
7.253PheLeu: 7.253 ± 2.259
1.813PheMet: 1.813 ± 1.125
2.72PheAsn: 2.72 ± 1.343
0.907PhePro: 0.907 ± 1.192
1.813PheGln: 1.813 ± 0.837
5.44PheArg: 5.44 ± 2.605
1.813PheSer: 1.813 ± 0.837
2.72PheThr: 2.72 ± 1.441
1.813PheVal: 1.813 ± 0.736
0.0PheTrp: 0.0 ± 0.0
1.813PheTyr: 1.813 ± 1.214
0.0PheXaa: 0.0 ± 0.0
Gly
2.72GlyAla: 2.72 ± 1.382
1.813GlyCys: 1.813 ± 0.958
1.813GlyAsp: 1.813 ± 1.291
4.533GlyGlu: 4.533 ± 1.118
1.813GlyPhe: 1.813 ± 1.453
3.626GlyGly: 3.626 ± 1.046
1.813GlyHis: 1.813 ± 0.837
2.72GlyIle: 2.72 ± 1.334
6.346GlyLys: 6.346 ± 2.768
2.72GlyLeu: 2.72 ± 2.168
0.907GlyMet: 0.907 ± 1.192
1.813GlyAsn: 1.813 ± 1.324
2.72GlyPro: 2.72 ± 1.147
3.626GlyGln: 3.626 ± 2.127
1.813GlyArg: 1.813 ± 1.291
2.72GlySer: 2.72 ± 0.768
3.626GlyThr: 3.626 ± 1.627
1.813GlyVal: 1.813 ± 1.236
0.0GlyTrp: 0.0 ± 0.0
0.907GlyTyr: 0.907 ± 1.192
0.0GlyXaa: 0.0 ± 0.0
His
1.813HisAla: 1.813 ± 1.552
1.813HisCys: 1.813 ± 1.453
1.813HisAsp: 1.813 ± 0.958
0.907HisGlu: 0.907 ± 0.776
3.626HisPhe: 3.626 ± 1.932
1.813HisGly: 1.813 ± 1.453
0.907HisHis: 0.907 ± 0.744
1.813HisIle: 1.813 ± 1.291
1.813HisLys: 1.813 ± 1.505
3.626HisLeu: 3.626 ± 1.46
0.907HisMet: 0.907 ± 0.985
2.72HisAsn: 2.72 ± 1.297
0.907HisPro: 0.907 ± 0.646
2.72HisGln: 2.72 ± 1.334
3.626HisArg: 3.626 ± 1.917
0.907HisSer: 0.907 ± 0.744
3.626HisThr: 3.626 ± 1.297
3.626HisVal: 3.626 ± 2.055
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
0.907IleCys: 0.907 ± 0.646
4.533IleAsp: 4.533 ± 2.479
0.907IleGlu: 0.907 ± 0.646
3.626IlePhe: 3.626 ± 2.023
2.72IleGly: 2.72 ± 1.653
1.813IleHis: 1.813 ± 1.453
0.0IleIle: 0.0 ± 0.0
6.346IleLys: 6.346 ± 1.952
1.813IleLeu: 1.813 ± 1.505
0.0IleMet: 0.0 ± 0.0
1.813IleAsn: 1.813 ± 1.278
0.907IlePro: 0.907 ± 0.646
4.533IleGln: 4.533 ± 2.08
2.72IleArg: 2.72 ± 1.66
6.346IleSer: 6.346 ± 1.916
2.72IleThr: 2.72 ± 1.199
2.72IleVal: 2.72 ± 1.368
2.72IleTrp: 2.72 ± 2.168
1.813IleTyr: 1.813 ± 0.958
0.0IleXaa: 0.0 ± 0.0
Lys
2.72LysAla: 2.72 ± 2.007
1.813LysCys: 1.813 ± 1.049
1.813LysAsp: 1.813 ± 1.291
4.533LysGlu: 4.533 ± 2.316
1.813LysPhe: 1.813 ± 1.236
2.72LysGly: 2.72 ± 0.768
1.813LysHis: 1.813 ± 0.736
2.72LysIle: 2.72 ± 1.368
1.813LysLys: 1.813 ± 0.736
0.907LysLeu: 0.907 ± 1.059
0.0LysMet: 0.0 ± 0.0
5.44LysAsn: 5.44 ± 2.294
2.72LysPro: 2.72 ± 1.368
1.813LysGln: 1.813 ± 1.214
2.72LysArg: 2.72 ± 1.577
3.626LysSer: 3.626 ± 1.046
5.44LysThr: 5.44 ± 1.737
4.533LysVal: 4.533 ± 1.995
0.907LysTrp: 0.907 ± 0.776
4.533LysTyr: 4.533 ± 1.806
0.0LysXaa: 0.0 ± 0.0
Leu
0.907LeuAla: 0.907 ± 0.646
1.813LeuCys: 1.813 ± 1.291
5.44LeuAsp: 5.44 ± 3.102
2.72LeuGlu: 2.72 ± 1.297
1.813LeuPhe: 1.813 ± 1.278
5.44LeuGly: 5.44 ± 1.923
4.533LeuHis: 4.533 ± 2.367
4.533LeuIle: 4.533 ± 2.623
5.44LeuLys: 5.44 ± 1.414
1.813LeuLeu: 1.813 ± 2.384
1.813LeuMet: 1.813 ± 1.552
4.533LeuAsn: 4.533 ± 1.536
0.907LeuPro: 0.907 ± 0.744
3.626LeuGln: 3.626 ± 1.464
5.44LeuArg: 5.44 ± 1.865
5.44LeuSer: 5.44 ± 2.571
7.253LeuThr: 7.253 ± 2.003
3.626LeuVal: 3.626 ± 1.471
0.0LeuTrp: 0.0 ± 0.0
3.626LeuTyr: 3.626 ± 1.939
0.0LeuXaa: 0.0 ± 0.0
Met
0.907MetAla: 0.907 ± 0.776
0.907MetCys: 0.907 ± 0.776
3.626MetAsp: 3.626 ± 2.24
0.907MetGlu: 0.907 ± 1.105
1.813MetPhe: 1.813 ± 1.552
1.813MetGly: 1.813 ± 1.159
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
1.813MetLeu: 1.813 ± 1.214
0.0MetMet: 0.0 ± 0.0
0.907MetAsn: 0.907 ± 0.776
0.907MetPro: 0.907 ± 0.646
0.0MetGln: 0.0 ± 0.0
0.907MetArg: 0.907 ± 0.744
1.813MetSer: 1.813 ± 1.291
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
1.813MetTrp: 1.813 ± 1.166
2.72MetTyr: 2.72 ± 1.772
0.0MetXaa: 0.0 ± 0.0
Asn
5.44AsnAla: 5.44 ± 2.292
1.813AsnCys: 1.813 ± 0.837
0.907AsnAsp: 0.907 ± 0.646
1.813AsnGlu: 1.813 ± 1.214
1.813AsnPhe: 1.813 ± 0.958
2.72AsnGly: 2.72 ± 1.199
2.72AsnHis: 2.72 ± 1.577
2.72AsnIle: 2.72 ± 1.147
0.0AsnLys: 0.0 ± 0.0
7.253AsnLeu: 7.253 ± 2.195
3.626AsnMet: 3.626 ± 1.664
2.72AsnAsn: 2.72 ± 1.015
3.626AsnPro: 3.626 ± 1.017
2.72AsnGln: 2.72 ± 1.146
5.44AsnArg: 5.44 ± 1.33
1.813AsnSer: 1.813 ± 1.552
2.72AsnThr: 2.72 ± 1.382
3.626AsnVal: 3.626 ± 1.448
0.907AsnTrp: 0.907 ± 0.646
4.533AsnTyr: 4.533 ± 1.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.626ProAla: 3.626 ± 1.109
2.72ProCys: 2.72 ± 1.389
2.72ProAsp: 2.72 ± 2.278
0.907ProGlu: 0.907 ± 0.646
1.813ProPhe: 1.813 ± 1.049
1.813ProGly: 1.813 ± 1.159
3.626ProHis: 3.626 ± 1.932
3.626ProIle: 3.626 ± 1.592
3.626ProLys: 3.626 ± 1.709
4.533ProLeu: 4.533 ± 1.485
0.0ProMet: 0.0 ± 0.0
5.44ProAsn: 5.44 ± 1.414
0.907ProPro: 0.907 ± 0.646
4.533ProGln: 4.533 ± 2.195
4.533ProArg: 4.533 ± 1.07
2.72ProSer: 2.72 ± 1.53
2.72ProThr: 2.72 ± 1.517
4.533ProVal: 4.533 ± 1.308
0.0ProTrp: 0.0 ± 0.0
0.907ProTyr: 0.907 ± 0.776
0.0ProXaa: 0.0 ± 0.0
Gln
4.533GlnAla: 4.533 ± 1.929
0.907GlnCys: 0.907 ± 0.646
3.626GlnAsp: 3.626 ± 1.868
3.626GlnGlu: 3.626 ± 1.387
2.72GlnPhe: 2.72 ± 1.382
2.72GlnGly: 2.72 ± 1.517
3.626GlnHis: 3.626 ± 2.521
2.72GlnIle: 2.72 ± 1.297
0.0GlnLys: 0.0 ± 0.0
2.72GlnLeu: 2.72 ± 1.334
0.907GlnMet: 0.907 ± 1.105
3.626GlnAsn: 3.626 ± 1.511
5.44GlnPro: 5.44 ± 3.103
7.253GlnGln: 7.253 ± 2.007
1.813GlnArg: 1.813 ± 1.159
3.626GlnSer: 3.626 ± 1.046
3.626GlnThr: 3.626 ± 1.942
4.533GlnVal: 4.533 ± 1.465
0.0GlnTrp: 0.0 ± 0.0
1.813GlnTyr: 1.813 ± 1.236
0.0GlnXaa: 0.0 ± 0.0
Arg
3.626ArgAla: 3.626 ± 1.576
1.813ArgCys: 1.813 ± 1.453
3.626ArgAsp: 3.626 ± 1.31
4.533ArgGlu: 4.533 ± 1.751
2.72ArgPhe: 2.72 ± 1.146
2.72ArgGly: 2.72 ± 0.768
1.813ArgHis: 1.813 ± 1.214
6.346ArgIle: 6.346 ± 1.916
3.626ArgLys: 3.626 ± 1.471
0.907ArgLeu: 0.907 ± 0.776
1.813ArgMet: 1.813 ± 1.552
1.813ArgAsn: 1.813 ± 1.453
5.44ArgPro: 5.44 ± 1.458
2.72ArgGln: 2.72 ± 1.835
6.346ArgArg: 6.346 ± 3.381
9.973ArgSer: 9.973 ± 3.58
3.626ArgThr: 3.626 ± 2.053
6.346ArgVal: 6.346 ± 1.786
0.0ArgTrp: 0.0 ± 0.0
1.813ArgTyr: 1.813 ± 1.214
0.0ArgXaa: 0.0 ± 0.0
Ser
1.813SerAla: 1.813 ± 1.291
0.907SerCys: 0.907 ± 1.192
3.626SerAsp: 3.626 ± 1.297
4.533SerGlu: 4.533 ± 1.721
3.626SerPhe: 3.626 ± 1.742
0.907SerGly: 0.907 ± 0.646
3.626SerHis: 3.626 ± 1.592
4.533SerIle: 4.533 ± 1.629
4.533SerLys: 4.533 ± 1.995
2.72SerLeu: 2.72 ± 1.937
1.813SerMet: 1.813 ± 1.128
4.533SerAsn: 4.533 ± 1.177
7.253SerPro: 7.253 ± 1.453
2.72SerGln: 2.72 ± 1.583
10.879SerArg: 10.879 ± 1.446
8.16SerSer: 8.16 ± 4.857
6.346SerThr: 6.346 ± 3.396
2.72SerVal: 2.72 ± 1.653
0.0SerTrp: 0.0 ± 0.0
1.813SerTyr: 1.813 ± 0.837
0.0SerXaa: 0.0 ± 0.0
Thr
6.346ThrAla: 6.346 ± 1.603
0.907ThrCys: 0.907 ± 1.105
0.907ThrAsp: 0.907 ± 1.105
0.907ThrGlu: 0.907 ± 0.776
2.72ThrPhe: 2.72 ± 2.128
5.44ThrGly: 5.44 ± 1.846
4.533ThrHis: 4.533 ± 2.443
1.813ThrIle: 1.813 ± 1.049
3.626ThrLys: 3.626 ± 1.472
7.253ThrLeu: 7.253 ± 1.938
1.813ThrMet: 1.813 ± 1.049
6.346ThrAsn: 6.346 ± 1.466
3.626ThrPro: 3.626 ± 1.387
2.72ThrGln: 2.72 ± 1.441
3.626ThrArg: 3.626 ± 1.1
1.813ThrSer: 1.813 ± 1.291
3.626ThrThr: 3.626 ± 2.369
2.72ThrVal: 2.72 ± 1.653
0.907ThrTrp: 0.907 ± 1.105
0.907ThrTyr: 0.907 ± 0.646
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
0.0ValCys: 0.0 ± 0.0
4.533ValAsp: 4.533 ± 1.049
2.72ValGlu: 2.72 ± 2.5
2.72ValPhe: 2.72 ± 1.343
0.907ValGly: 0.907 ± 0.776
1.813ValHis: 1.813 ± 1.214
6.346ValIle: 6.346 ± 2.913
5.44ValLys: 5.44 ± 1.744
5.44ValLeu: 5.44 ± 2.03
1.813ValMet: 1.813 ± 1.627
2.72ValAsn: 2.72 ± 1.772
4.533ValPro: 4.533 ± 1.39
5.44ValGln: 5.44 ± 1.992
3.626ValArg: 3.626 ± 3.104
1.813ValSer: 1.813 ± 1.291
2.72ValThr: 2.72 ± 2.328
2.72ValVal: 2.72 ± 1.368
0.907ValTrp: 0.907 ± 0.646
2.72ValTyr: 2.72 ± 1.368
0.0ValXaa: 0.0 ± 0.0
Trp
2.72TrpAla: 2.72 ± 1.937
0.0TrpCys: 0.0 ± 0.0
0.907TrpAsp: 0.907 ± 1.192
0.907TrpGlu: 0.907 ± 1.059
0.0TrpPhe: 0.0 ± 0.0
0.907TrpGly: 0.907 ± 0.646
0.907TrpHis: 0.907 ± 0.776
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.907TrpMet: 0.907 ± 0.776
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.907TrpGln: 0.907 ± 0.646
0.907TrpArg: 0.907 ± 0.744
0.907TrpSer: 0.907 ± 0.744
1.813TrpThr: 1.813 ± 1.236
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.813TrpTyr: 1.813 ± 1.159
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.626TyrAla: 3.626 ± 1.31
0.0TyrCys: 0.0 ± 0.0
0.907TyrAsp: 0.907 ± 0.776
1.813TyrGlu: 1.813 ± 2.384
2.72TyrPhe: 2.72 ± 1.015
1.813TyrGly: 1.813 ± 0.837
0.0TyrHis: 0.0 ± 0.0
2.72TyrIle: 2.72 ± 1.382
0.907TyrLys: 0.907 ± 0.646
4.533TyrLeu: 4.533 ± 1.905
0.907TyrMet: 0.907 ± 0.776
3.626TyrAsn: 3.626 ± 1.939
1.813TyrPro: 1.813 ± 1.159
1.813TyrGln: 1.813 ± 0.736
1.813TyrArg: 1.813 ± 1.552
4.533TyrSer: 4.533 ± 2.264
0.907TyrThr: 0.907 ± 0.776
3.626TyrVal: 3.626 ± 1.785
0.0TyrTrp: 0.0 ± 0.0
0.907TyrTyr: 0.907 ± 0.744
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1104 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski