Amino acid dipepetide frequency for Philantomba monticola polyomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.465AlaAla: 2.465 ± 0.455
2.465AlaCys: 2.465 ± 0.664
2.113AlaAsp: 2.113 ± 0.473
2.817AlaGlu: 2.817 ± 0.626
2.465AlaPhe: 2.465 ± 0.801
1.761AlaGly: 1.761 ± 0.554
1.761AlaHis: 1.761 ± 0.567
2.817AlaIle: 2.817 ± 0.932
3.169AlaLys: 3.169 ± 0.935
5.634AlaLeu: 5.634 ± 1.768
0.352AlaMet: 0.352 ± 0.325
3.169AlaAsn: 3.169 ± 1.047
3.169AlaPro: 3.169 ± 0.794
1.408AlaGln: 1.408 ± 0.313
1.408AlaArg: 1.408 ± 0.975
9.155AlaSer: 9.155 ± 2.164
2.817AlaThr: 2.817 ± 1.043
7.394AlaVal: 7.394 ± 1.439
1.761AlaTrp: 1.761 ± 0.544
2.465AlaTyr: 2.465 ± 0.442
0.0AlaXaa: 0.0 ± 0.0
Cys
2.113CysAla: 2.113 ± 0.473
2.113CysCys: 2.113 ± 1.073
0.704CysAsp: 0.704 ± 0.262
0.352CysGlu: 0.352 ± 0.429
2.817CysPhe: 2.817 ± 0.997
1.408CysGly: 1.408 ± 0.562
0.704CysHis: 0.704 ± 0.262
2.817CysIle: 2.817 ± 1.358
2.113CysLys: 2.113 ± 0.473
3.521CysLeu: 3.521 ± 0.924
0.0CysMet: 0.0 ± 0.0
1.761CysAsn: 1.761 ± 0.463
2.465CysPro: 2.465 ± 0.455
2.465CysGln: 2.465 ± 0.894
0.704CysArg: 0.704 ± 0.262
1.056CysSer: 1.056 ± 0.38
2.113CysThr: 2.113 ± 0.786
2.113CysVal: 2.113 ± 0.454
0.0CysTrp: 0.0 ± 0.0
0.704CysTyr: 0.704 ± 0.536
0.0CysXaa: 0.0 ± 0.0
Asp
2.817AspAla: 2.817 ± 0.504
1.408AspCys: 1.408 ± 0.524
2.817AspAsp: 2.817 ± 1.048
3.873AspGlu: 3.873 ± 0.918
3.521AspPhe: 3.521 ± 1.31
2.465AspGly: 2.465 ± 1.261
0.704AspHis: 0.704 ± 0.262
5.986AspIle: 5.986 ± 0.532
6.69AspLys: 6.69 ± 1.142
5.282AspLeu: 5.282 ± 0.606
0.352AspMet: 0.352 ± 0.325
1.056AspAsn: 1.056 ± 0.237
1.761AspPro: 1.761 ± 0.513
1.056AspGln: 1.056 ± 0.237
1.408AspArg: 1.408 ± 0.499
0.704AspSer: 0.704 ± 0.262
0.352AspThr: 0.352 ± 0.325
2.817AspVal: 2.817 ± 0.558
0.352AspTrp: 0.352 ± 0.318
1.056AspTyr: 1.056 ± 0.237
0.0AspXaa: 0.0 ± 0.0
Glu
5.282GluAla: 5.282 ± 1.199
0.704GluCys: 0.704 ± 0.262
4.225GluAsp: 4.225 ± 0.834
8.803GluGlu: 8.803 ± 0.848
3.521GluPhe: 3.521 ± 0.992
6.69GluGly: 6.69 ± 0.981
1.761GluHis: 1.761 ± 0.379
2.113GluIle: 2.113 ± 0.569
4.577GluLys: 4.577 ± 0.372
3.521GluLeu: 3.521 ± 0.831
2.465GluMet: 2.465 ± 0.575
4.225GluAsn: 4.225 ± 0.617
1.056GluPro: 1.056 ± 0.975
1.056GluGln: 1.056 ± 0.666
1.761GluArg: 1.761 ± 0.567
7.042GluSer: 7.042 ± 1.233
2.113GluThr: 2.113 ± 0.473
6.338GluVal: 6.338 ± 0.576
1.761GluTrp: 1.761 ± 0.463
0.704GluTyr: 0.704 ± 0.262
0.0GluXaa: 0.0 ± 0.0
Phe
3.873PheAla: 3.873 ± 1.109
2.465PheCys: 2.465 ± 1.04
2.113PheAsp: 2.113 ± 0.786
4.225PheGlu: 4.225 ± 1.572
2.113PhePhe: 2.113 ± 0.603
3.169PheGly: 3.169 ± 0.959
0.704PheHis: 0.704 ± 0.262
1.056PheIle: 1.056 ± 0.38
3.169PheLys: 3.169 ± 0.56
4.225PheLeu: 4.225 ± 0.807
2.113PheMet: 2.113 ± 0.837
2.113PheAsn: 2.113 ± 0.454
3.521PhePro: 3.521 ± 0.837
2.113PheGln: 2.113 ± 0.657
2.113PheArg: 2.113 ± 0.437
5.634PheSer: 5.634 ± 0.915
3.169PheThr: 3.169 ± 0.56
2.465PheVal: 2.465 ± 0.511
0.0PheTrp: 0.0 ± 0.0
1.408PheTyr: 1.408 ± 0.462
0.0PheXaa: 0.0 ± 0.0
Gly
3.169GlyAla: 3.169 ± 1.283
1.056GlyCys: 1.056 ± 0.421
2.465GlyAsp: 2.465 ± 1.108
4.577GlyGlu: 4.577 ± 0.534
2.113GlyPhe: 2.113 ± 0.626
3.873GlyGly: 3.873 ± 1.537
0.352GlyHis: 0.352 ± 0.429
4.225GlyIle: 4.225 ± 1.224
2.113GlyLys: 2.113 ± 0.437
8.803GlyLeu: 8.803 ± 1.301
0.0GlyMet: 0.0 ± 0.0
2.817GlyAsn: 2.817 ± 1.051
1.761GlyPro: 1.761 ± 0.536
5.282GlyGln: 5.282 ± 1.403
1.408GlyArg: 1.408 ± 0.462
3.521GlySer: 3.521 ± 0.78
0.352GlyThr: 0.352 ± 0.429
4.93GlyVal: 4.93 ± 0.535
0.704GlyTrp: 0.704 ± 0.417
2.113GlyTyr: 2.113 ± 0.53
0.0GlyXaa: 0.0 ± 0.0
His
3.873HisAla: 3.873 ± 0.601
1.761HisCys: 1.761 ± 0.585
0.0HisAsp: 0.0 ± 0.0
0.704HisGlu: 0.704 ± 0.262
0.0HisPhe: 0.0 ± 0.0
0.352HisGly: 0.352 ± 0.325
1.056HisHis: 1.056 ± 0.237
0.704HisIle: 0.704 ± 0.417
0.704HisLys: 0.704 ± 0.262
0.704HisLeu: 0.704 ± 0.484
1.056HisMet: 1.056 ± 0.237
0.352HisAsn: 0.352 ± 0.325
2.113HisPro: 2.113 ± 0.53
1.761HisGln: 1.761 ± 0.379
1.408HisArg: 1.408 ± 0.792
2.113HisSer: 2.113 ± 0.786
0.704HisThr: 0.704 ± 0.262
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.704HisTyr: 0.704 ± 0.262
0.0HisXaa: 0.0 ± 0.0
Ile
1.408IleAla: 1.408 ± 0.65
1.761IleCys: 1.761 ± 0.379
3.873IleAsp: 3.873 ± 0.53
6.69IleGlu: 6.69 ± 1.026
1.761IlePhe: 1.761 ± 0.631
1.056IleGly: 1.056 ± 0.544
0.704IleHis: 0.704 ± 0.65
2.817IleIle: 2.817 ± 0.932
2.465IleLys: 2.465 ± 0.765
4.93IleLeu: 4.93 ± 1.114
1.408IleMet: 1.408 ± 0.462
0.704IleAsn: 0.704 ± 0.484
4.225IlePro: 4.225 ± 0.448
1.408IleGln: 1.408 ± 0.705
0.704IleArg: 0.704 ± 0.826
4.577IleSer: 4.577 ± 1.097
5.634IleThr: 5.634 ± 1.32
1.761IleVal: 1.761 ± 0.57
0.704IleTrp: 0.704 ± 0.536
0.704IleTyr: 0.704 ± 0.6
0.0IleXaa: 0.0 ± 0.0
Lys
4.93LysAla: 4.93 ± 0.816
1.761LysCys: 1.761 ± 0.379
1.761LysAsp: 1.761 ± 0.513
3.521LysGlu: 3.521 ± 0.899
4.225LysPhe: 4.225 ± 1.044
5.634LysGly: 5.634 ± 0.841
2.817LysHis: 2.817 ± 0.504
2.817LysIle: 2.817 ± 0.764
8.099LysLys: 8.099 ± 0.783
4.93LysLeu: 4.93 ± 1.168
0.704LysMet: 0.704 ± 0.6
1.408LysAsn: 1.408 ± 0.356
2.465LysPro: 2.465 ± 0.607
1.761LysGln: 1.761 ± 0.567
6.69LysArg: 6.69 ± 1.122
8.099LysSer: 8.099 ± 1.523
6.338LysThr: 6.338 ± 0.9
2.113LysVal: 2.113 ± 0.473
0.352LysTrp: 0.352 ± 0.318
2.113LysTyr: 2.113 ± 0.847
0.0LysXaa: 0.0 ± 0.0
Leu
5.634LeuAla: 5.634 ± 1.581
2.113LeuCys: 2.113 ± 0.516
8.099LeuAsp: 8.099 ± 0.784
5.986LeuGlu: 5.986 ± 0.587
7.042LeuPhe: 7.042 ± 0.998
3.873LeuGly: 3.873 ± 0.909
2.817LeuHis: 2.817 ± 1.048
8.099LeuIle: 8.099 ± 1.085
5.986LeuLys: 5.986 ± 0.637
20.07LeuLeu: 20.07 ± 2.399
4.577LeuMet: 4.577 ± 0.858
5.634LeuAsn: 5.634 ± 0.83
4.225LeuPro: 4.225 ± 1.804
5.282LeuGln: 5.282 ± 0.612
5.634LeuArg: 5.634 ± 1.163
2.817LeuSer: 2.817 ± 0.758
4.577LeuThr: 4.577 ± 0.641
2.113LeuVal: 2.113 ± 0.632
1.408LeuTrp: 1.408 ± 0.499
1.408LeuTyr: 1.408 ± 0.356
0.0LeuXaa: 0.0 ± 0.0
Met
1.761MetAla: 1.761 ± 0.535
0.0MetCys: 0.0 ± 0.0
2.113MetAsp: 2.113 ± 0.59
0.0MetGlu: 0.0 ± 0.0
0.704MetPhe: 0.704 ± 0.65
0.704MetGly: 0.704 ± 0.417
0.352MetHis: 0.352 ± 0.413
2.817MetIle: 2.817 ± 0.831
0.352MetLys: 0.352 ± 0.413
1.761MetLeu: 1.761 ± 0.631
0.0MetMet: 0.0 ± 0.0
1.761MetAsn: 1.761 ± 0.734
1.408MetPro: 1.408 ± 0.562
0.352MetGln: 0.352 ± 0.318
1.761MetArg: 1.761 ± 0.489
1.408MetSer: 1.408 ± 0.759
1.761MetThr: 1.761 ± 0.463
0.0MetVal: 0.0 ± 0.0
1.056MetTrp: 1.056 ± 0.237
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.704AsnAla: 0.704 ± 0.262
2.465AsnCys: 2.465 ± 0.801
0.704AsnAsp: 0.704 ± 0.65
2.465AsnGlu: 2.465 ± 0.718
1.761AsnPhe: 1.761 ± 0.379
1.761AsnGly: 1.761 ± 1.017
0.0AsnHis: 0.0 ± 0.0
3.521AsnIle: 3.521 ± 0.814
3.521AsnLys: 3.521 ± 1.31
5.282AsnLeu: 5.282 ± 0.911
0.704AsnMet: 0.704 ± 0.536
2.113AsnAsn: 2.113 ± 1.04
4.93AsnPro: 4.93 ± 1.152
2.817AsnGln: 2.817 ± 0.741
0.352AsnArg: 0.352 ± 0.318
5.282AsnSer: 5.282 ± 0.857
2.465AsnThr: 2.465 ± 0.442
2.817AsnVal: 2.817 ± 0.612
0.704AsnTrp: 0.704 ± 0.262
1.056AsnTyr: 1.056 ± 0.237
0.0AsnXaa: 0.0 ± 0.0
Pro
4.93ProAla: 4.93 ± 0.53
1.408ProCys: 1.408 ± 0.524
4.225ProAsp: 4.225 ± 0.495
4.577ProGlu: 4.577 ± 0.953
2.113ProPhe: 2.113 ± 0.608
4.225ProGly: 4.225 ± 0.53
0.0ProHis: 0.0 ± 0.0
2.113ProIle: 2.113 ± 0.717
5.634ProLys: 5.634 ± 1.258
6.338ProLeu: 6.338 ± 0.588
1.056ProMet: 1.056 ± 0.843
2.817ProAsn: 2.817 ± 0.612
6.69ProPro: 6.69 ± 2.924
1.056ProGln: 1.056 ± 0.577
1.408ProArg: 1.408 ± 1.003
1.761ProSer: 1.761 ± 0.734
3.521ProThr: 3.521 ± 1.023
2.817ProVal: 2.817 ± 1.427
0.0ProTrp: 0.0 ± 0.0
1.761ProTyr: 1.761 ± 1.408
0.0ProXaa: 0.0 ± 0.0
Gln
3.169GlnAla: 3.169 ± 1.264
0.704GlnCys: 0.704 ± 0.536
0.352GlnAsp: 0.352 ± 0.325
4.577GlnGlu: 4.577 ± 0.98
2.465GlnPhe: 2.465 ± 0.865
2.113GlnGly: 2.113 ± 0.959
1.408GlnHis: 1.408 ± 0.684
0.704GlnIle: 0.704 ± 0.262
5.282GlnLys: 5.282 ± 1.094
3.521GlnLeu: 3.521 ± 0.758
0.352GlnMet: 0.352 ± 0.411
0.704GlnAsn: 0.704 ± 0.417
2.113GlnPro: 2.113 ± 0.689
0.0GlnGln: 0.0 ± 0.0
4.225GlnArg: 4.225 ± 1.044
2.817GlnSer: 2.817 ± 0.633
1.761GlnThr: 1.761 ± 0.97
2.113GlnVal: 2.113 ± 0.454
0.0GlnTrp: 0.0 ± 0.0
0.704GlnTyr: 0.704 ± 0.488
0.0GlnXaa: 0.0 ± 0.0
Arg
2.817ArgAla: 2.817 ± 0.764
1.408ArgCys: 1.408 ± 0.562
3.169ArgAsp: 3.169 ± 1.224
2.113ArgGlu: 2.113 ± 0.841
2.465ArgPhe: 2.465 ± 0.442
1.761ArgGly: 1.761 ± 0.379
0.352ArgHis: 0.352 ± 0.318
0.704ArgIle: 0.704 ± 0.598
2.113ArgLys: 2.113 ± 0.837
4.225ArgLeu: 4.225 ± 0.743
1.056ArgMet: 1.056 ± 0.961
3.521ArgAsn: 3.521 ± 0.382
1.056ArgPro: 1.056 ± 0.421
1.056ArgGln: 1.056 ± 1.239
4.577ArgArg: 4.577 ± 0.771
2.817ArgSer: 2.817 ± 0.75
1.056ArgThr: 1.056 ± 0.237
3.521ArgVal: 3.521 ± 1.081
0.352ArgTrp: 0.352 ± 0.318
1.761ArgTyr: 1.761 ± 0.815
0.0ArgXaa: 0.0 ± 0.0
Ser
3.521SerAla: 3.521 ± 0.834
1.056SerCys: 1.056 ± 0.975
3.169SerAsp: 3.169 ± 0.398
5.282SerGlu: 5.282 ± 1.317
3.873SerPhe: 3.873 ± 0.754
5.282SerGly: 5.282 ± 0.981
1.408SerHis: 1.408 ± 0.524
2.113SerIle: 2.113 ± 0.583
6.338SerLys: 6.338 ± 0.932
9.155SerLeu: 9.155 ± 1.383
0.704SerMet: 0.704 ± 0.404
4.225SerAsn: 4.225 ± 0.862
5.282SerPro: 5.282 ± 0.689
3.521SerGln: 3.521 ± 0.63
2.113SerArg: 2.113 ± 0.569
6.338SerSer: 6.338 ± 1.2
7.042SerThr: 7.042 ± 1.376
3.169SerVal: 3.169 ± 0.921
1.761SerTrp: 1.761 ± 0.554
3.521SerTyr: 3.521 ± 0.992
0.0SerXaa: 0.0 ± 0.0
Thr
1.408ThrAla: 1.408 ± 0.313
2.113ThrCys: 2.113 ± 0.893
1.056ThrAsp: 1.056 ± 0.38
3.521ThrGlu: 3.521 ± 1.765
2.465ThrPhe: 2.465 ± 0.801
2.465ThrGly: 2.465 ± 0.567
0.0ThrHis: 0.0 ± 0.0
1.056ThrIle: 1.056 ± 0.38
2.465ThrLys: 2.465 ± 0.664
7.394ThrLeu: 7.394 ± 0.878
1.408ThrMet: 1.408 ± 0.524
2.465ThrAsn: 2.465 ± 0.455
5.282ThrPro: 5.282 ± 0.911
3.521ThrGln: 3.521 ± 0.464
0.704ThrArg: 0.704 ± 0.262
5.282ThrSer: 5.282 ± 1.26
3.873ThrThr: 3.873 ± 0.744
5.986ThrVal: 5.986 ± 0.638
0.704ThrTrp: 0.704 ± 0.488
1.056ThrTyr: 1.056 ± 0.84
0.0ThrXaa: 0.0 ± 0.0
Val
5.282ValAla: 5.282 ± 0.5
2.465ValCys: 2.465 ± 1.158
2.113ValAsp: 2.113 ± 0.786
3.873ValGlu: 3.873 ± 1.429
2.817ValPhe: 2.817 ± 0.932
3.873ValGly: 3.873 ± 1.429
0.704ValHis: 0.704 ± 0.582
1.408ValIle: 1.408 ± 0.313
4.577ValLys: 4.577 ± 0.861
4.93ValLeu: 4.93 ± 0.822
0.704ValMet: 0.704 ± 0.826
3.169ValAsn: 3.169 ± 1.047
3.169ValPro: 3.169 ± 0.523
1.761ValGln: 1.761 ± 0.536
2.817ValArg: 2.817 ± 1.245
4.93ValSer: 4.93 ± 0.822
2.113ValThr: 2.113 ± 0.473
1.761ValVal: 1.761 ± 0.513
1.056ValTrp: 1.056 ± 0.676
1.408ValTyr: 1.408 ± 0.418
0.0ValXaa: 0.0 ± 0.0
Trp
0.352TrpAla: 0.352 ± 0.429
0.704TrpCys: 0.704 ± 0.262
0.0TrpAsp: 0.0 ± 0.0
0.704TrpGlu: 0.704 ± 0.417
1.056TrpPhe: 1.056 ± 0.537
0.704TrpGly: 0.704 ± 0.536
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.408TrpLys: 1.408 ± 0.499
0.0TrpLeu: 0.0 ± 0.0
0.704TrpMet: 0.704 ± 0.547
0.704TrpAsn: 0.704 ± 0.262
0.352TrpPro: 0.352 ± 0.429
1.408TrpGln: 1.408 ± 0.499
0.0TrpArg: 0.0 ± 0.0
1.408TrpSer: 1.408 ± 0.505
0.352TrpThr: 0.352 ± 0.318
0.352TrpVal: 0.352 ± 0.318
0.704TrpTrp: 0.704 ± 0.536
2.465TrpTyr: 2.465 ± 0.442
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.056TyrAla: 1.056 ± 0.237
2.113TyrCys: 2.113 ± 0.59
1.408TyrAsp: 1.408 ± 0.524
1.056TyrGlu: 1.056 ± 0.237
2.465TyrPhe: 2.465 ± 1.036
2.465TyrGly: 2.465 ± 0.562
2.465TyrHis: 2.465 ± 0.779
1.408TyrIle: 1.408 ± 0.915
1.761TyrLys: 1.761 ± 0.872
3.169TyrLeu: 3.169 ± 0.569
0.0TyrMet: 0.0 ± 0.0
0.704TyrAsn: 0.704 ± 0.262
1.408TyrPro: 1.408 ± 1.3
0.0TyrGln: 0.0 ± 0.0
0.704TyrArg: 0.704 ± 0.262
2.465TyrSer: 2.465 ± 0.607
2.113TyrThr: 2.113 ± 0.812
0.352TyrVal: 0.352 ± 0.429
0.0TyrTrp: 0.0 ± 0.0
1.056TyrTyr: 1.056 ± 0.61
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (2841 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski