Amino acid dipepetide frequency for Mycoplana dimorpha

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.761AlaAla: 17.761 ± 0.187	1.051AlaCys: 1.051 ± 0.034	6.872AlaAsp: 6.872 ± 0.083	7.928AlaGlu: 7.928 ± 0.096	4.667AlaPhe: 4.667 ± 0.068	10.993AlaGly: 10.993 ± 0.11	2.204AlaHis: 2.204 ± 0.041	6.957AlaIle: 6.957 ± 0.089	3.881AlaLys: 3.881 ± 0.065	12.99AlaLeu: 12.99 ± 0.112	3.596AlaMet: 3.596 ± 0.056	2.936AlaAsn: 2.936 ± 0.052	5.184AlaPro: 5.184 ± 0.079	3.419AlaGln: 3.419 ± 0.065	8.601AlaArg: 8.601 ± 0.089	6.335AlaSer: 6.335 ± 0.075	6.022AlaThr: 6.022 ± 0.077	8.977AlaVal: 8.977 ± 0.097	1.468AlaTrp: 1.468 ± 0.038	2.686AlaTyr: 2.686 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	0.915CysAla: 0.915 ± 0.028	0.105CysCys: 0.105 ± 0.01	0.537CysAsp: 0.537 ± 0.024	0.449CysGlu: 0.449 ± 0.02	0.328CysPhe: 0.328 ± 0.014	0.927CysGly: 0.927 ± 0.03	0.234CysHis: 0.234 ± 0.015	0.42CysIle: 0.42 ± 0.019	0.195CysLys: 0.195 ± 0.012	0.828CysLeu: 0.828 ± 0.026	0.158CysMet: 0.158 ± 0.012	0.211CysAsn: 0.211 ± 0.014	0.386CysPro: 0.386 ± 0.018	0.232CysGln: 0.232 ± 0.014	0.64CysArg: 0.64 ± 0.021	0.432CysSer: 0.432 ± 0.021	0.402CysThr: 0.402 ± 0.02	0.58CysVal: 0.58 ± 0.023	0.111CysTrp: 0.111 ± 0.009	0.225CysTyr: 0.225 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	6.502AspAla: 6.502 ± 0.082	0.485AspCys: 0.485 ± 0.02	3.037AspAsp: 3.037 ± 0.053	3.614AspGlu: 3.614 ± 0.056	2.251AspPhe: 2.251 ± 0.046	5.224AspGly: 5.224 ± 0.082	1.207AspHis: 1.207 ± 0.033	3.114AspIle: 3.114 ± 0.053	1.82AspLys: 1.82 ± 0.039	5.75AspLeu: 5.75 ± 0.072	1.362AspMet: 1.362 ± 0.032	1.416AspAsn: 1.416 ± 0.034	3.36AspPro: 3.36 ± 0.051	1.667AspGln: 1.667 ± 0.038	4.425AspArg: 4.425 ± 0.069	2.058AspSer: 2.058 ± 0.038	2.48AspThr: 2.48 ± 0.04	4.123AspVal: 4.123 ± 0.06	0.932AspTrp: 0.932 ± 0.024	1.507AspTyr: 1.507 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	7.932GluAla: 7.932 ± 0.1	0.359GluCys: 0.359 ± 0.017	2.743GluAsp: 2.743 ± 0.055	3.44GluGlu: 3.44 ± 0.071	1.818GluPhe: 1.818 ± 0.039	4.286GluGly: 4.286 ± 0.06	1.238GluHis: 1.238 ± 0.027	3.696GluIle: 3.696 ± 0.063	2.533GluLys: 2.533 ± 0.054	5.344GluLeu: 5.344 ± 0.064	1.597GluMet: 1.597 ± 0.042	1.732GluAsn: 1.732 ± 0.04	2.792GluPro: 2.792 ± 0.051	2.119GluGln: 2.119 ± 0.047	5.168GluArg: 5.168 ± 0.07	2.313GluSer: 2.313 ± 0.047	3.564GluThr: 3.564 ± 0.053	3.923GluVal: 3.923 ± 0.063	0.694GluTrp: 0.694 ± 0.026	1.031GluTyr: 1.031 ± 0.031	0.0GluXaa: 0.0 ± 0.0
Phe	4.671PheAla: 4.671 ± 0.061	0.424PheCys: 0.424 ± 0.018	2.738PheAsp: 2.738 ± 0.045	2.16PheGlu: 2.16 ± 0.037	1.557PhePhe: 1.557 ± 0.041	3.748PheGly: 3.748 ± 0.057	0.831PheHis: 0.831 ± 0.029	1.78PheIle: 1.78 ± 0.043	1.055PheLys: 1.055 ± 0.032	3.494PheLeu: 3.494 ± 0.058	0.852PheMet: 0.852 ± 0.026	1.061PheAsn: 1.061 ± 0.029	1.643PhePro: 1.643 ± 0.039	1.007PheGln: 1.007 ± 0.026	2.421PheArg: 2.421 ± 0.047	2.442PheSer: 2.442 ± 0.039	1.964PheThr: 1.964 ± 0.037	3.057PheVal: 3.057 ± 0.054	0.568PheTrp: 0.568 ± 0.023	0.961PheTyr: 0.961 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	8.955GlyAla: 8.955 ± 0.095	0.816GlyCys: 0.816 ± 0.027	4.401GlyAsp: 4.401 ± 0.064	4.938GlyGlu: 4.938 ± 0.065	3.56GlyPhe: 3.56 ± 0.051	7.327GlyGly: 7.327 ± 0.109	1.905GlyHis: 1.905 ± 0.037	4.939GlyIle: 4.939 ± 0.07	3.472GlyLys: 3.472 ± 0.055	8.774GlyLeu: 8.774 ± 0.086	2.387GlyMet: 2.387 ± 0.05	2.294GlyAsn: 2.294 ± 0.053	3.364GlyPro: 3.364 ± 0.051	2.706GlyGln: 2.706 ± 0.045	6.315GlyArg: 6.315 ± 0.071	4.681GlySer: 4.681 ± 0.06	4.674GlyThr: 4.674 ± 0.075	5.981GlyVal: 5.981 ± 0.07	1.309GlyTrp: 1.309 ± 0.034	2.445GlyTyr: 2.445 ± 0.049	0.001GlyXaa: 0.001 ± 0.001
His	2.297HisAla: 2.297 ± 0.042	0.231HisCys: 0.231 ± 0.015	1.278HisAsp: 1.278 ± 0.04	1.079HisGlu: 1.079 ± 0.029	0.909HisPhe: 0.909 ± 0.023	1.967HisGly: 1.967 ± 0.045	0.568HisHis: 0.568 ± 0.027	0.954HisIle: 0.954 ± 0.03	0.503HisLys: 0.503 ± 0.019	2.019HisLeu: 2.019 ± 0.041	0.507HisMet: 0.507 ± 0.018	0.462HisAsn: 0.462 ± 0.019	1.322HisPro: 1.322 ± 0.032	0.61HisGln: 0.61 ± 0.02	1.434HisArg: 1.434 ± 0.035	0.981HisSer: 0.981 ± 0.029	0.808HisThr: 0.808 ± 0.024	1.532HisVal: 1.532 ± 0.034	0.293HisTrp: 0.293 ± 0.014	0.562HisTyr: 0.562 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	7.751IleAla: 7.751 ± 0.089	0.527IleCys: 0.527 ± 0.019	3.683IleAsp: 3.683 ± 0.059	3.686IleGlu: 3.686 ± 0.056	1.837IlePhe: 1.837 ± 0.039	5.284IleGly: 5.284 ± 0.076	0.928IleHis: 0.928 ± 0.028	2.434IleIle: 2.434 ± 0.049	1.48IleLys: 1.48 ± 0.036	4.682IleLeu: 4.682 ± 0.068	1.056IleMet: 1.056 ± 0.03	1.486IleAsn: 1.486 ± 0.037	2.344IlePro: 2.344 ± 0.041	1.196IleGln: 1.196 ± 0.028	3.515IleArg: 3.515 ± 0.051	2.95IleSer: 2.95 ± 0.05	2.701IleThr: 2.701 ± 0.049	4.507IleVal: 4.507 ± 0.064	0.543IleTrp: 0.543 ± 0.021	1.197IleTyr: 1.197 ± 0.03	0.0IleXaa: 0.0 ± 0.0
Lys	4.578LysAla: 4.578 ± 0.066	0.179LysCys: 0.179 ± 0.013	1.888LysAsp: 1.888 ± 0.045	1.836LysGlu: 1.836 ± 0.041	0.949LysPhe: 0.949 ± 0.024	2.716LysGly: 2.716 ± 0.053	0.607LysHis: 0.607 ± 0.023	1.821LysIle: 1.821 ± 0.04	1.394LysLys: 1.394 ± 0.043	3.291LysLeu: 3.291 ± 0.055	0.843LysMet: 0.843 ± 0.023	0.957LysAsn: 0.957 ± 0.029	2.02LysPro: 2.02 ± 0.041	1.038LysGln: 1.038 ± 0.031	2.317LysArg: 2.317 ± 0.05	1.898LysSer: 1.898 ± 0.044	2.027LysThr: 2.027 ± 0.043	2.602LysVal: 2.602 ± 0.045	0.371LysTrp: 0.371 ± 0.019	0.672LysTyr: 0.672 ± 0.025	0.0LysXaa: 0.0 ± 0.0
Leu	13.38LeuAla: 13.38 ± 0.131	0.876LeuCys: 0.876 ± 0.025	5.802LeuAsp: 5.802 ± 0.073	5.476LeuGlu: 5.476 ± 0.065	3.814LeuPhe: 3.814 ± 0.061	8.004LeuGly: 8.004 ± 0.095	1.79LeuHis: 1.79 ± 0.041	4.858LeuIle: 4.858 ± 0.077	3.803LeuLys: 3.803 ± 0.061	9.583LeuLeu: 9.583 ± 0.125	2.336LeuMet: 2.336 ± 0.048	2.571LeuAsn: 2.571 ± 0.048	5.376LeuPro: 5.376 ± 0.077	2.859LeuGln: 2.859 ± 0.05	6.477LeuArg: 6.477 ± 0.073	6.71LeuSer: 6.71 ± 0.075	5.281LeuThr: 5.281 ± 0.07	7.786LeuVal: 7.786 ± 0.089	1.093LeuTrp: 1.093 ± 0.03	2.167LeuTyr: 2.167 ± 0.042	0.0LeuXaa: 0.0 ± 0.0
Met	3.222MetAla: 3.222 ± 0.051	0.145MetCys: 0.145 ± 0.01	1.131MetAsp: 1.131 ± 0.029	1.235MetGlu: 1.235 ± 0.03	0.715MetPhe: 0.715 ± 0.025	1.733MetGly: 1.733 ± 0.037	0.467MetHis: 0.467 ± 0.022	1.421MetIle: 1.421 ± 0.035	1.064MetLys: 1.064 ± 0.028	2.703MetLeu: 2.703 ± 0.05	0.725MetMet: 0.725 ± 0.025	0.835MetAsn: 0.835 ± 0.024	1.486MetPro: 1.486 ± 0.034	0.885MetGln: 0.885 ± 0.026	1.861MetArg: 1.861 ± 0.039	1.698MetSer: 1.698 ± 0.034	1.876MetThr: 1.876 ± 0.031	1.772MetVal: 1.772 ± 0.04	0.192MetTrp: 0.192 ± 0.012	0.349MetTyr: 0.349 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.24AsnAla: 3.24 ± 0.056	0.238AsnCys: 0.238 ± 0.014	1.478AsnAsp: 1.478 ± 0.037	1.328AsnGlu: 1.328 ± 0.036	1.002AsnPhe: 1.002 ± 0.027	2.543AsnGly: 2.543 ± 0.047	0.494AsnHis: 0.494 ± 0.018	1.38AsnIle: 1.38 ± 0.036	0.72AsnLys: 0.72 ± 0.026	2.617AsnLeu: 2.617 ± 0.049	0.651AsnMet: 0.651 ± 0.023	0.711AsnAsn: 0.711 ± 0.023	1.786AsnPro: 1.786 ± 0.038	0.748AsnGln: 0.748 ± 0.024	1.933AsnArg: 1.933 ± 0.041	1.241AsnSer: 1.241 ± 0.032	1.3AsnThr: 1.3 ± 0.035	2.058AsnVal: 2.058 ± 0.041	0.467AsnTrp: 0.467 ± 0.018	0.686AsnTyr: 0.686 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	6.185ProAla: 6.185 ± 0.087	0.296ProCys: 0.296 ± 0.015	3.416ProAsp: 3.416 ± 0.06	3.681ProGlu: 3.681 ± 0.051	2.011ProPhe: 2.011 ± 0.039	4.392ProGly: 4.392 ± 0.058	1.055ProHis: 1.055 ± 0.028	2.316ProIle: 2.316 ± 0.045	1.734ProLys: 1.734 ± 0.039	4.654ProLeu: 4.654 ± 0.064	1.16ProMet: 1.16 ± 0.03	1.278ProAsn: 1.278 ± 0.03	2.331ProPro: 2.331 ± 0.049	1.672ProGln: 1.672 ± 0.038	2.677ProArg: 2.677 ± 0.047	2.665ProSer: 2.665 ± 0.049	2.363ProThr: 2.363 ± 0.043	4.286ProVal: 4.286 ± 0.059	0.629ProTrp: 0.629 ± 0.021	1.189ProTyr: 1.189 ± 0.027	0.0ProXaa: 0.0 ± 0.0
Gln	3.964GlnAla: 3.964 ± 0.056	0.189GlnCys: 0.189 ± 0.012	1.355GlnAsp: 1.355 ± 0.035	1.55GlnGlu: 1.55 ± 0.033	1.119GlnPhe: 1.119 ± 0.027	2.201GlnGly: 2.201 ± 0.039	0.631GlnHis: 0.631 ± 0.024	1.729GlnIle: 1.729 ± 0.038	1.172GlnLys: 1.172 ± 0.031	2.753GlnLeu: 2.753 ± 0.05	0.934GlnMet: 0.934 ± 0.03	0.82GlnAsn: 0.82 ± 0.029	1.704GlnPro: 1.704 ± 0.039	1.247GlnGln: 1.247 ± 0.047	2.304GlnArg: 2.304 ± 0.046	1.705GlnSer: 1.705 ± 0.037	1.68GlnThr: 1.68 ± 0.04	2.163GlnVal: 2.163 ± 0.042	0.4GlnTrp: 0.4 ± 0.019	0.615GlnTyr: 0.615 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	7.589ArgAla: 7.589 ± 0.081	0.487ArgCys: 0.487 ± 0.017	3.999ArgAsp: 3.999 ± 0.065	3.995ArgGlu: 3.995 ± 0.064	2.962ArgPhe: 2.962 ± 0.048	4.612ArgGly: 4.612 ± 0.064	1.809ArgHis: 1.809 ± 0.042	4.224ArgIle: 4.224 ± 0.059	2.577ArgLys: 2.577 ± 0.052	7.776ArgLeu: 7.776 ± 0.102	1.994ArgMet: 1.994 ± 0.037	2.057ArgAsn: 2.057 ± 0.044	3.588ArgPro: 3.588 ± 0.054	2.737ArgGln: 2.737 ± 0.043	5.769ArgArg: 5.769 ± 0.09	3.887ArgSer: 3.887 ± 0.052	3.465ArgThr: 3.465 ± 0.059	4.515ArgVal: 4.515 ± 0.06	0.916ArgTrp: 0.916 ± 0.031	1.74ArgTyr: 1.74 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	6.206SerAla: 6.206 ± 0.072	0.411SerCys: 0.411 ± 0.019	2.945SerAsp: 2.945 ± 0.055	2.859SerGlu: 2.859 ± 0.05	2.364SerPhe: 2.364 ± 0.045	5.676SerGly: 5.676 ± 0.074	1.123SerHis: 1.123 ± 0.031	2.941SerIle: 2.941 ± 0.049	1.629SerLys: 1.629 ± 0.036	5.538SerLeu: 5.538 ± 0.078	1.355SerMet: 1.355 ± 0.034	1.407SerAsn: 1.407 ± 0.037	2.778SerPro: 2.778 ± 0.049	1.6SerGln: 1.6 ± 0.038	3.692SerArg: 3.692 ± 0.062	2.932SerSer: 2.932 ± 0.057	2.639SerThr: 2.639 ± 0.054	4.088SerVal: 4.088 ± 0.046	0.728SerTrp: 0.728 ± 0.023	1.337SerTyr: 1.337 ± 0.03	0.0SerXaa: 0.0 ± 0.0
Thr	6.377ThrAla: 6.377 ± 0.071	0.408ThrCys: 0.408 ± 0.018	2.814ThrAsp: 2.814 ± 0.049	2.674ThrGlu: 2.674 ± 0.043	2.109ThrPhe: 2.109 ± 0.042	5.123ThrGly: 5.123 ± 0.071	0.974ThrHis: 0.974 ± 0.029	3.113ThrIle: 3.113 ± 0.049	1.483ThrLys: 1.483 ± 0.04	5.592ThrLeu: 5.592 ± 0.07	1.326ThrMet: 1.326 ± 0.027	1.322ThrAsn: 1.322 ± 0.034	2.828ThrPro: 2.828 ± 0.047	1.285ThrGln: 1.285 ± 0.028	3.097ThrArg: 3.097 ± 0.047	2.756ThrSer: 2.756 ± 0.048	2.802ThrThr: 2.802 ± 0.047	4.42ThrVal: 4.42 ± 0.059	0.616ThrTrp: 0.616 ± 0.022	1.235ThrTyr: 1.235 ± 0.034	0.0ThrXaa: 0.0 ± 0.0
Val	9.303ValAla: 9.303 ± 0.096	0.682ValCys: 0.682 ± 0.023	4.105ValAsp: 4.105 ± 0.055	4.543ValGlu: 4.543 ± 0.063	2.906ValPhe: 2.906 ± 0.055	5.495ValGly: 5.495 ± 0.07	1.445ValHis: 1.445 ± 0.033	4.107ValIle: 4.107 ± 0.064	2.359ValLys: 2.359 ± 0.042	7.662ValLeu: 7.662 ± 0.087	1.845ValMet: 1.845 ± 0.041	2.008ValAsn: 2.008 ± 0.043	3.903ValPro: 3.903 ± 0.056	1.93ValGln: 1.93 ± 0.04	5.114ValArg: 5.114 ± 0.057	4.524ValSer: 4.524 ± 0.065	4.521ValThr: 4.521 ± 0.058	6.293ValVal: 6.293 ± 0.086	0.887ValTrp: 0.887 ± 0.03	1.51ValTyr: 1.51 ± 0.035	0.0ValXaa: 0.0 ± 0.0
Trp	1.192TrpAla: 1.192 ± 0.032	0.122TrpCys: 0.122 ± 0.01	0.628TrpAsp: 0.628 ± 0.02	0.582TrpGlu: 0.582 ± 0.025	0.556TrpPhe: 0.556 ± 0.019	0.813TrpGly: 0.813 ± 0.027	0.318TrpHis: 0.318 ± 0.016	0.633TrpIle: 0.633 ± 0.023	0.497TrpLys: 0.497 ± 0.021	1.613TrpLeu: 1.613 ± 0.038	0.352TrpMet: 0.352 ± 0.016	0.46TrpAsn: 0.46 ± 0.02	0.653TrpPro: 0.653 ± 0.022	0.534TrpGln: 0.534 ± 0.019	1.05TrpArg: 1.05 ± 0.032	0.823TrpSer: 0.823 ± 0.027	0.702TrpThr: 0.702 ± 0.023	0.752TrpVal: 0.752 ± 0.024	0.22TrpTrp: 0.22 ± 0.013	0.302TrpTyr: 0.302 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.509TyrAla: 2.509 ± 0.047	0.283TyrCys: 0.283 ± 0.014	1.485TyrAsp: 1.485 ± 0.036	1.269TyrGlu: 1.269 ± 0.028	1.001TyrPhe: 1.001 ± 0.028	2.18TyrGly: 2.18 ± 0.045	0.488TyrHis: 0.488 ± 0.018	0.952TyrIle: 0.952 ± 0.026	0.63TyrLys: 0.63 ± 0.025	2.38TyrLeu: 2.38 ± 0.041	0.478TyrMet: 0.478 ± 0.02	0.592TyrAsn: 0.592 ± 0.023	1.14TyrPro: 1.14 ± 0.029	0.745TyrGln: 0.745 ± 0.027	1.889TyrArg: 1.889 ± 0.036	1.217TyrSer: 1.217 ± 0.03	1.088TyrThr: 1.088 ± 0.03	1.724TyrVal: 1.724 ± 0.039	0.366TyrTrp: 0.366 ± 0.018	0.642TyrTyr: 0.642 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.001	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.009XaaXaa: 0.009 ± 0.008

Statistics based on 4217 proteins (1319512 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---