Amino acid dipepetide frequency for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.342AlaAla: 11.342 ± 0.739
2.645AlaCys: 2.645 ± 0.272
5.925AlaAsp: 5.925 ± 0.576
4.323AlaGlu: 4.323 ± 0.361
3.866AlaPhe: 3.866 ± 0.357
4.323AlaGly: 4.323 ± 0.354
2.772AlaHis: 2.772 ± 0.291
3.153AlaIle: 3.153 ± 0.308
3.535AlaLys: 3.535 ± 0.298
9.46AlaLeu: 9.46 ± 0.632
1.577AlaMet: 1.577 ± 0.187
4.603AlaAsn: 4.603 ± 0.338
5.773AlaPro: 5.773 ± 0.448
4.578AlaGln: 4.578 ± 0.418
6.663AlaArg: 6.663 ± 0.512
5.29AlaSer: 5.29 ± 0.364
5.188AlaThr: 5.188 ± 0.349
7.222AlaVal: 7.222 ± 0.532
0.509AlaTrp: 0.509 ± 0.151
2.925AlaTyr: 2.925 ± 0.286
0.0AlaXaa: 0.0 ± 0.0
Cys
3.026CysAla: 3.026 ± 0.325
0.636CysCys: 0.636 ± 0.14
1.628CysAsp: 1.628 ± 0.198
1.144CysGlu: 1.144 ± 0.168
1.119CysPhe: 1.119 ± 0.159
1.068CysGly: 1.068 ± 0.183
0.509CysHis: 0.509 ± 0.107
1.068CysIle: 1.068 ± 0.16
1.399CysLys: 1.399 ± 0.177
2.213CysLeu: 2.213 ± 0.236
0.458CysMet: 0.458 ± 0.094
1.272CysAsn: 1.272 ± 0.193
1.195CysPro: 1.195 ± 0.229
0.483CysGln: 0.483 ± 0.104
1.882CysArg: 1.882 ± 0.192
1.551CysSer: 1.551 ± 0.203
1.17CysThr: 1.17 ± 0.18
2.543CysVal: 2.543 ± 0.23
0.127CysTrp: 0.127 ± 0.092
0.966CysTyr: 0.966 ± 0.131
0.0CysXaa: 0.0 ± 0.0
Asp
7.07AspAla: 7.07 ± 0.464
1.424AspCys: 1.424 ± 0.216
4.349AspAsp: 4.349 ± 0.482
4.247AspGlu: 4.247 ± 0.299
2.034AspPhe: 2.034 ± 0.233
3.484AspGly: 3.484 ± 0.3
1.45AspHis: 1.45 ± 0.19
2.391AspIle: 2.391 ± 0.24
3.001AspLys: 3.001 ± 0.275
5.137AspLeu: 5.137 ± 0.403
1.399AspMet: 1.399 ± 0.173
3.052AspAsn: 3.052 ± 0.252
2.289AspPro: 2.289 ± 0.219
1.628AspGln: 1.628 ± 0.212
3.586AspArg: 3.586 ± 0.305
3.408AspSer: 3.408 ± 0.356
3.179AspThr: 3.179 ± 0.305
3.866AspVal: 3.866 ± 0.329
0.559AspTrp: 0.559 ± 0.15
2.619AspTyr: 2.619 ± 0.234
0.0AspXaa: 0.0 ± 0.0
Glu
4.018GluAla: 4.018 ± 0.336
1.526GluCys: 1.526 ± 0.247
2.162GluAsp: 2.162 ± 0.248
2.569GluGlu: 2.569 ± 0.288
3.281GluPhe: 3.281 ± 0.285
1.551GluGly: 1.551 ± 0.229
1.678GluHis: 1.678 ± 0.204
2.594GluIle: 2.594 ± 0.247
1.831GluLys: 1.831 ± 0.226
5.188GluLeu: 5.188 ± 0.363
1.272GluMet: 1.272 ± 0.152
2.67GluAsn: 2.67 ± 0.303
2.238GluPro: 2.238 ± 0.247
1.933GluGln: 1.933 ± 0.275
3.942GluArg: 3.942 ± 0.283
2.823GluSer: 2.823 ± 0.266
3.357GluThr: 3.357 ± 0.276
2.747GluVal: 2.747 ± 0.258
0.458GluTrp: 0.458 ± 0.107
2.034GluTyr: 2.034 ± 0.286
0.0GluXaa: 0.0 ± 0.0
Phe
4.73PheAla: 4.73 ± 0.353
1.551PheCys: 1.551 ± 0.194
3.764PheAsp: 3.764 ± 0.339
3.128PheGlu: 3.128 ± 0.27
1.704PhePhe: 1.704 ± 0.254
2.441PheGly: 2.441 ± 0.274
0.788PheHis: 0.788 ± 0.139
2.06PheIle: 2.06 ± 0.267
3.306PheLys: 3.306 ± 0.323
4.044PheLeu: 4.044 ± 0.319
1.094PheMet: 1.094 ± 0.194
2.899PheAsn: 2.899 ± 0.285
1.373PhePro: 1.373 ± 0.193
1.017PheGln: 1.017 ± 0.162
2.034PheArg: 2.034 ± 0.219
2.314PheSer: 2.314 ± 0.235
2.263PheThr: 2.263 ± 0.235
4.628PheVal: 4.628 ± 0.399
0.203PheTrp: 0.203 ± 0.09
1.856PheTyr: 1.856 ± 0.178
0.0PheXaa: 0.0 ± 0.0
Gly
6.002GlyAla: 6.002 ± 0.394
0.763GlyCys: 0.763 ± 0.137
3.611GlyAsp: 3.611 ± 0.304
2.289GlyGlu: 2.289 ± 0.213
1.933GlyPhe: 1.933 ± 0.238
2.874GlyGly: 2.874 ± 0.318
1.348GlyHis: 1.348 ± 0.187
0.814GlyIle: 0.814 ± 0.143
2.136GlyLys: 2.136 ± 0.216
3.916GlyLeu: 3.916 ± 0.375
0.712GlyMet: 0.712 ± 0.13
1.933GlyAsn: 1.933 ± 0.272
1.551GlyPro: 1.551 ± 0.211
1.653GlyGln: 1.653 ± 0.243
2.772GlyArg: 2.772 ± 0.326
1.984GlySer: 1.984 ± 0.207
1.806GlyThr: 1.806 ± 0.201
3.789GlyVal: 3.789 ± 0.383
0.407GlyTrp: 0.407 ± 0.099
1.653GlyTyr: 1.653 ± 0.182
0.0GlyXaa: 0.0 ± 0.0
His
2.645HisAla: 2.645 ± 0.254
0.61HisCys: 0.61 ± 0.128
1.526HisAsp: 1.526 ± 0.195
1.424HisGlu: 1.424 ± 0.218
1.221HisPhe: 1.221 ± 0.154
1.424HisGly: 1.424 ± 0.177
1.017HisHis: 1.017 ± 0.129
1.094HisIle: 1.094 ± 0.2
1.424HisLys: 1.424 ± 0.179
2.238HisLeu: 2.238 ± 0.232
0.61HisMet: 0.61 ± 0.13
1.78HisAsn: 1.78 ± 0.178
0.89HisPro: 0.89 ± 0.164
0.687HisGln: 0.687 ± 0.121
1.017HisArg: 1.017 ± 0.168
1.373HisSer: 1.373 ± 0.221
1.221HisThr: 1.221 ± 0.185
2.085HisVal: 2.085 ± 0.258
0.509HisTrp: 0.509 ± 0.138
0.865HisTyr: 0.865 ± 0.157
0.0HisXaa: 0.0 ± 0.0
Ile
2.848IleAla: 2.848 ± 0.274
1.221IleCys: 1.221 ± 0.21
3.052IleAsp: 3.052 ± 0.269
2.391IleGlu: 2.391 ± 0.249
1.5IlePhe: 1.5 ± 0.195
2.136IleGly: 2.136 ± 0.225
0.738IleHis: 0.738 ± 0.133
1.856IleIle: 1.856 ± 0.207
3.077IleLys: 3.077 ± 0.311
3.484IleLeu: 3.484 ± 0.379
1.195IleMet: 1.195 ± 0.171
3.23IleAsn: 3.23 ± 0.39
1.17IlePro: 1.17 ± 0.166
1.043IleGln: 1.043 ± 0.175
1.958IleArg: 1.958 ± 0.214
2.34IleSer: 2.34 ± 0.299
2.06IleThr: 2.06 ± 0.23
3.942IleVal: 3.942 ± 0.261
0.229IleTrp: 0.229 ± 0.073
1.704IleTyr: 1.704 ± 0.215
0.0IleXaa: 0.0 ± 0.0
Lys
2.772LysAla: 2.772 ± 0.29
1.424LysCys: 1.424 ± 0.192
1.882LysAsp: 1.882 ± 0.218
2.416LysGlu: 2.416 ± 0.256
2.416LysPhe: 2.416 ± 0.265
1.424LysGly: 1.424 ± 0.242
1.297LysHis: 1.297 ± 0.178
3.052LysIle: 3.052 ± 0.298
2.874LysLys: 2.874 ± 0.288
5.824LysLeu: 5.824 ± 0.43
2.136LysMet: 2.136 ± 0.26
3.459LysAsn: 3.459 ± 0.341
1.729LysPro: 1.729 ± 0.231
1.882LysGln: 1.882 ± 0.18
4.12LysArg: 4.12 ± 0.338
2.594LysSer: 2.594 ± 0.331
3.433LysThr: 3.433 ± 0.321
2.569LysVal: 2.569 ± 0.294
0.458LysTrp: 0.458 ± 0.11
2.034LysTyr: 2.034 ± 0.266
0.0LysXaa: 0.0 ± 0.0
Leu
8.036LeuAla: 8.036 ± 0.465
2.263LeuCys: 2.263 ± 0.236
5.264LeuAsp: 5.264 ± 0.337
4.323LeuGlu: 4.323 ± 0.316
5.137LeuPhe: 5.137 ± 0.332
3.484LeuGly: 3.484 ± 0.278
2.594LeuHis: 2.594 ± 0.263
4.984LeuIle: 4.984 ± 0.327
5.137LeuLys: 5.137 ± 0.406
10.02LeuLeu: 10.02 ± 0.476
2.467LeuMet: 2.467 ± 0.242
5.773LeuAsn: 5.773 ± 0.411
3.789LeuPro: 3.789 ± 0.303
5.646LeuGln: 5.646 ± 0.447
6.459LeuArg: 6.459 ± 0.411
5.417LeuSer: 5.417 ± 0.371
5.061LeuThr: 5.061 ± 0.409
6.612LeuVal: 6.612 ± 0.427
0.661LeuTrp: 0.661 ± 0.12
3.306LeuTyr: 3.306 ± 0.335
0.0LeuXaa: 0.0 ± 0.0
Met
1.958MetAla: 1.958 ± 0.176
0.814MetCys: 0.814 ± 0.138
1.475MetAsp: 1.475 ± 0.191
1.195MetGlu: 1.195 ± 0.169
1.272MetPhe: 1.272 ± 0.189
0.763MetGly: 0.763 ± 0.143
0.814MetHis: 0.814 ± 0.176
0.916MetIle: 0.916 ± 0.146
1.043MetLys: 1.043 ± 0.163
2.645MetLeu: 2.645 ± 0.248
0.636MetMet: 0.636 ± 0.106
1.373MetAsn: 1.373 ± 0.185
1.246MetPro: 1.246 ± 0.198
1.17MetGln: 1.17 ± 0.166
1.755MetArg: 1.755 ± 0.19
1.5MetSer: 1.5 ± 0.22
1.017MetThr: 1.017 ± 0.168
1.5MetVal: 1.5 ± 0.231
0.178MetTrp: 0.178 ± 0.06
1.373MetTyr: 1.373 ± 0.171
0.0MetXaa: 0.0 ± 0.0
Asn
5.315AsnAla: 5.315 ± 0.348
1.17AsnCys: 1.17 ± 0.161
3.179AsnAsp: 3.179 ± 0.24
3.179AsnGlu: 3.179 ± 0.28
2.314AsnPhe: 2.314 ± 0.231
2.721AsnGly: 2.721 ± 0.297
1.068AsnHis: 1.068 ± 0.181
1.806AsnIle: 1.806 ± 0.255
3.738AsnLys: 3.738 ± 0.328
5.035AsnLeu: 5.035 ± 0.411
1.475AsnMet: 1.475 ± 0.178
4.12AsnAsn: 4.12 ± 0.332
1.45AsnPro: 1.45 ± 0.189
1.068AsnGln: 1.068 ± 0.164
3.281AsnArg: 3.281 ± 0.355
3.509AsnSer: 3.509 ± 0.362
3.153AsnThr: 3.153 ± 0.31
4.756AsnVal: 4.756 ± 0.375
0.585AsnTrp: 0.585 ± 0.127
2.518AsnTyr: 2.518 ± 0.22
0.0AsnXaa: 0.0 ± 0.0
Pro
4.654ProAla: 4.654 ± 0.331
0.916ProCys: 0.916 ± 0.161
2.721ProAsp: 2.721 ± 0.272
1.806ProGlu: 1.806 ± 0.226
2.162ProPhe: 2.162 ± 0.22
1.984ProGly: 1.984 ± 0.298
1.475ProHis: 1.475 ± 0.189
1.475ProIle: 1.475 ± 0.195
1.272ProLys: 1.272 ± 0.154
3.713ProLeu: 3.713 ± 0.306
0.916ProMet: 0.916 ± 0.127
1.933ProAsn: 1.933 ± 0.19
4.4ProPro: 4.4 ± 0.867
2.289ProGln: 2.289 ± 0.439
2.619ProArg: 2.619 ± 0.302
3.204ProSer: 3.204 ± 0.612
3.688ProThr: 3.688 ± 1.037
2.569ProVal: 2.569 ± 0.305
0.432ProTrp: 0.432 ± 0.108
1.373ProTyr: 1.373 ± 0.187
0.0ProXaa: 0.0 ± 0.0
Gln
2.187GlnAla: 2.187 ± 0.294
0.89GlnCys: 0.89 ± 0.171
1.577GlnAsp: 1.577 ± 0.211
1.628GlnGlu: 1.628 ± 0.217
2.213GlnPhe: 2.213 ± 0.194
0.738GlnGly: 0.738 ± 0.156
1.068GlnHis: 1.068 ± 0.147
1.755GlnIle: 1.755 ± 0.18
1.856GlnLys: 1.856 ± 0.206
5.035GlnLeu: 5.035 ± 0.416
1.195GlnMet: 1.195 ± 0.178
1.984GlnAsn: 1.984 ± 0.255
1.78GlnPro: 1.78 ± 0.409
2.747GlnGln: 2.747 ± 0.455
3.103GlnArg: 3.103 ± 0.305
1.958GlnSer: 1.958 ± 0.215
2.416GlnThr: 2.416 ± 0.33
2.187GlnVal: 2.187 ± 0.251
0.407GlnTrp: 0.407 ± 0.104
1.704GlnTyr: 1.704 ± 0.196
0.0GlnXaa: 0.0 ± 0.0
Arg
6.968ArgAla: 6.968 ± 0.434
1.78ArgCys: 1.78 ± 0.204
3.764ArgAsp: 3.764 ± 0.294
3.204ArgGlu: 3.204 ± 0.27
2.975ArgPhe: 2.975 ± 0.232
3.153ArgGly: 3.153 ± 0.32
1.78ArgHis: 1.78 ± 0.204
2.391ArgIle: 2.391 ± 0.241
2.416ArgLys: 2.416 ± 0.243
6.332ArgLeu: 6.332 ± 0.439
1.5ArgMet: 1.5 ± 0.187
2.391ArgAsn: 2.391 ± 0.218
3.001ArgPro: 3.001 ± 0.318
2.772ArgGln: 2.772 ± 0.316
6.816ArgArg: 6.816 ± 0.654
3.611ArgSer: 3.611 ± 0.373
2.747ArgThr: 2.747 ± 0.26
5.747ArgVal: 5.747 ± 0.395
0.509ArgTrp: 0.509 ± 0.133
2.467ArgTyr: 2.467 ± 0.26
0.0ArgXaa: 0.0 ± 0.0
Ser
6.027SerAla: 6.027 ± 0.398
1.017SerCys: 1.017 ± 0.154
4.069SerAsp: 4.069 ± 0.38
2.772SerGlu: 2.772 ± 0.263
2.721SerPhe: 2.721 ± 0.28
3.052SerGly: 3.052 ± 0.291
0.865SerHis: 0.865 ± 0.144
2.034SerIle: 2.034 ± 0.204
2.696SerLys: 2.696 ± 0.295
5.569SerLeu: 5.569 ± 0.362
1.221SerMet: 1.221 ± 0.198
2.721SerAsn: 2.721 ± 0.324
2.899SerPro: 2.899 ± 0.644
1.729SerGln: 1.729 ± 0.222
3.204SerArg: 3.204 ± 0.339
4.018SerSer: 4.018 ± 0.369
3.23SerThr: 3.23 ± 0.309
4.578SerVal: 4.578 ± 0.364
0.458SerTrp: 0.458 ± 0.122
1.882SerTyr: 1.882 ± 0.217
0.0SerXaa: 0.0 ± 0.0
Thr
5.035ThrAla: 5.035 ± 0.327
1.297ThrCys: 1.297 ± 0.159
3.001ThrAsp: 3.001 ± 0.301
2.06ThrGlu: 2.06 ± 0.248
3.052ThrPhe: 3.052 ± 0.271
2.619ThrGly: 2.619 ± 0.256
1.144ThrHis: 1.144 ± 0.185
2.772ThrIle: 2.772 ± 0.266
1.907ThrLys: 1.907 ± 0.262
5.595ThrLeu: 5.595 ± 0.406
1.424ThrMet: 1.424 ± 0.169
2.925ThrAsn: 2.925 ± 0.261
3.611ThrPro: 3.611 ± 0.976
1.907ThrGln: 1.907 ± 0.227
3.23ThrArg: 3.23 ± 0.335
3.052ThrSer: 3.052 ± 0.318
3.637ThrThr: 3.637 ± 0.337
4.272ThrVal: 4.272 ± 0.37
0.483ThrTrp: 0.483 ± 0.124
1.984ThrTyr: 1.984 ± 0.213
0.0ThrXaa: 0.0 ± 0.0
Val
7.172ValAla: 7.172 ± 0.435
2.187ValCys: 2.187 ± 0.255
4.476ValAsp: 4.476 ± 0.366
3.586ValGlu: 3.586 ± 0.285
3.891ValPhe: 3.891 ± 0.301
2.899ValGly: 2.899 ± 0.238
2.289ValHis: 2.289 ± 0.254
2.797ValIle: 2.797 ± 0.224
4.069ValLys: 4.069 ± 0.311
7.019ValLeu: 7.019 ± 0.461
1.755ValMet: 1.755 ± 0.191
4.171ValAsn: 4.171 ± 0.304
3.637ValPro: 3.637 ± 0.352
2.95ValGln: 2.95 ± 0.261
5.086ValArg: 5.086 ± 0.4
4.044ValSer: 4.044 ± 0.324
3.306ValThr: 3.306 ± 0.282
5.976ValVal: 5.976 ± 0.403
0.636ValTrp: 0.636 ± 0.18
3.357ValTyr: 3.357 ± 0.272
0.0ValXaa: 0.0 ± 0.0
Trp
0.738TrpAla: 0.738 ± 0.162
0.28TrpCys: 0.28 ± 0.088
0.61TrpAsp: 0.61 ± 0.109
0.28TrpGlu: 0.28 ± 0.105
0.356TrpPhe: 0.356 ± 0.083
0.331TrpGly: 0.331 ± 0.1
0.178TrpHis: 0.178 ± 0.064
0.178TrpIle: 0.178 ± 0.067
0.356TrpLys: 0.356 ± 0.105
0.712TrpLeu: 0.712 ± 0.116
0.178TrpMet: 0.178 ± 0.063
0.585TrpAsn: 0.585 ± 0.135
0.636TrpPro: 0.636 ± 0.127
0.356TrpGln: 0.356 ± 0.084
0.839TrpArg: 0.839 ± 0.152
0.407TrpSer: 0.407 ± 0.103
0.559TrpThr: 0.559 ± 0.131
0.356TrpVal: 0.356 ± 0.107
0.127TrpTrp: 0.127 ± 0.049
0.229TrpTyr: 0.229 ± 0.073
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.128TyrAla: 3.128 ± 0.257
1.043TyrCys: 1.043 ± 0.145
2.136TyrAsp: 2.136 ± 0.223
1.907TyrGlu: 1.907 ± 0.192
2.034TyrPhe: 2.034 ± 0.251
1.475TyrGly: 1.475 ± 0.181
0.788TyrHis: 0.788 ± 0.141
2.009TyrIle: 2.009 ± 0.215
2.721TyrLys: 2.721 ± 0.282
3.255TyrLeu: 3.255 ± 0.352
1.399TyrMet: 1.399 ± 0.173
2.569TyrAsn: 2.569 ± 0.265
0.941TyrPro: 0.941 ± 0.136
0.89TyrGln: 0.89 ± 0.137
1.958TyrArg: 1.958 ± 0.24
2.365TyrSer: 2.365 ± 0.199
2.518TyrThr: 2.518 ± 0.298
3.357TyrVal: 3.357 ± 0.252
0.356TyrTrp: 0.356 ± 0.086
1.984TyrTyr: 1.984 ± 0.288
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 152 proteins (39323 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski