Amino acid dipepetide frequency for Stenotrophobium rhamnosiphilum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.653AlaAla: 13.653 ± 0.132	1.087AlaCys: 1.087 ± 0.029	6.003AlaAsp: 6.003 ± 0.082	6.263AlaGlu: 6.263 ± 0.08	3.634AlaPhe: 3.634 ± 0.055	8.503AlaGly: 8.503 ± 0.093	2.066AlaHis: 2.066 ± 0.048	5.618AlaIle: 5.618 ± 0.078	4.986AlaLys: 4.986 ± 0.084	11.902AlaLeu: 11.902 ± 0.125	2.86AlaMet: 2.86 ± 0.051	3.406AlaAsn: 3.406 ± 0.06	5.116AlaPro: 5.116 ± 0.089	4.546AlaGln: 4.546 ± 0.068	6.422AlaArg: 6.422 ± 0.078	6.312AlaSer: 6.312 ± 0.075	5.789AlaThr: 5.789 ± 0.079	7.812AlaVal: 7.812 ± 0.088	1.462AlaTrp: 1.462 ± 0.04	2.676AlaTyr: 2.676 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	1.074CysAla: 1.074 ± 0.032	0.106CysCys: 0.106 ± 0.011	0.489CysAsp: 0.489 ± 0.018	0.518CysGlu: 0.518 ± 0.022	0.332CysPhe: 0.332 ± 0.016	0.963CysGly: 0.963 ± 0.034	0.232CysHis: 0.232 ± 0.014	0.456CysIle: 0.456 ± 0.019	0.366CysLys: 0.366 ± 0.018	0.794CysLeu: 0.794 ± 0.027	0.205CysMet: 0.205 ± 0.013	0.329CysAsn: 0.329 ± 0.019	0.447CysPro: 0.447 ± 0.023	0.272CysGln: 0.272 ± 0.016	0.558CysArg: 0.558 ± 0.022	0.661CysSer: 0.661 ± 0.028	0.534CysThr: 0.534 ± 0.027	0.684CysVal: 0.684 ± 0.023	0.115CysTrp: 0.115 ± 0.011	0.25CysTyr: 0.25 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	6.245AspAla: 6.245 ± 0.083	0.521AspCys: 0.521 ± 0.021	2.596AspAsp: 2.596 ± 0.049	3.087AspGlu: 3.087 ± 0.059	2.201AspPhe: 2.201 ± 0.047	4.467AspGly: 4.467 ± 0.07	1.124AspHis: 1.124 ± 0.029	2.87AspIle: 2.87 ± 0.054	2.176AspLys: 2.176 ± 0.049	5.443AspLeu: 5.443 ± 0.071	1.157AspMet: 1.157 ± 0.028	1.554AspAsn: 1.554 ± 0.036	2.791AspPro: 2.791 ± 0.053	1.917AspGln: 1.917 ± 0.036	3.032AspArg: 3.032 ± 0.048	2.782AspSer: 2.782 ± 0.056	2.46AspThr: 2.46 ± 0.05	3.969AspVal: 3.969 ± 0.064	0.91AspTrp: 0.91 ± 0.03	1.669AspTyr: 1.669 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	5.802GluAla: 5.802 ± 0.078	0.44GluCys: 0.44 ± 0.019	2.395GluAsp: 2.395 ± 0.047	2.752GluGlu: 2.752 ± 0.05	2.029GluPhe: 2.029 ± 0.042	3.677GluGly: 3.677 ± 0.059	1.332GluHis: 1.332 ± 0.036	3.353GluIle: 3.353 ± 0.06	2.708GluLys: 2.708 ± 0.057	5.894GluLeu: 5.894 ± 0.082	1.394GluMet: 1.394 ± 0.032	1.738GluAsn: 1.738 ± 0.041	2.145GluPro: 2.145 ± 0.046	2.54GluGln: 2.54 ± 0.053	3.898GluArg: 3.898 ± 0.063	2.997GluSer: 2.997 ± 0.054	2.893GluThr: 2.893 ± 0.052	3.852GluVal: 3.852 ± 0.057	0.771GluTrp: 0.771 ± 0.026	1.328GluTyr: 1.328 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	3.958PheAla: 3.958 ± 0.057	0.416PheCys: 0.416 ± 0.02	2.421PheAsp: 2.421 ± 0.052	2.065PheGlu: 2.065 ± 0.041	1.528PhePhe: 1.528 ± 0.037	3.449PheGly: 3.449 ± 0.061	0.78PheHis: 0.78 ± 0.026	2.016PheIle: 2.016 ± 0.041	1.58PheLys: 1.58 ± 0.035	3.273PheLeu: 3.273 ± 0.06	0.927PheMet: 0.927 ± 0.028	1.467PheAsn: 1.467 ± 0.037	1.592PhePro: 1.592 ± 0.04	1.117PheGln: 1.117 ± 0.031	1.92PheArg: 1.92 ± 0.041	2.643PheSer: 2.643 ± 0.047	2.171PheThr: 2.171 ± 0.045	2.718PheVal: 2.718 ± 0.054	0.549PheTrp: 0.549 ± 0.024	1.113PheTyr: 1.113 ± 0.032	0.0PheXaa: 0.0 ± 0.0
Gly	7.837GlyAla: 7.837 ± 0.09	0.85GlyCys: 0.85 ± 0.031	4.094GlyAsp: 4.094 ± 0.063	4.084GlyGlu: 4.084 ± 0.059	3.394GlyPhe: 3.394 ± 0.054	6.516GlyGly: 6.516 ± 0.1	1.792GlyHis: 1.792 ± 0.044	4.614GlyIle: 4.614 ± 0.069	3.94GlyLys: 3.94 ± 0.062	7.956GlyLeu: 7.956 ± 0.09	2.086GlyMet: 2.086 ± 0.048	2.576GlyAsn: 2.576 ± 0.059	2.791GlyPro: 2.791 ± 0.049	2.852GlyGln: 2.852 ± 0.047	4.437GlyArg: 4.437 ± 0.066	4.75GlySer: 4.75 ± 0.083	4.45GlyThr: 4.45 ± 0.081	6.25GlyVal: 6.25 ± 0.08	1.227GlyTrp: 1.227 ± 0.035	2.602GlyTyr: 2.602 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	2.18HisAla: 2.18 ± 0.039	0.243HisCys: 0.243 ± 0.015	1.097HisAsp: 1.097 ± 0.038	1.128HisGlu: 1.128 ± 0.028	0.931HisPhe: 0.931 ± 0.024	1.818HisGly: 1.818 ± 0.034	0.638HisHis: 0.638 ± 0.026	1.081HisIle: 1.081 ± 0.032	0.706HisLys: 0.706 ± 0.024	2.125HisLeu: 2.125 ± 0.045	0.511HisMet: 0.511 ± 0.022	0.646HisAsn: 0.646 ± 0.026	1.259HisPro: 1.259 ± 0.035	0.772HisGln: 0.772 ± 0.028	1.268HisArg: 1.268 ± 0.034	1.167HisSer: 1.167 ± 0.033	0.948HisThr: 0.948 ± 0.029	1.462HisVal: 1.462 ± 0.041	0.389HisTrp: 0.389 ± 0.019	0.701HisTyr: 0.701 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	6.616IleAla: 6.616 ± 0.081	0.533IleCys: 0.533 ± 0.02	3.283IleAsp: 3.283 ± 0.061	3.505IleGlu: 3.505 ± 0.06	1.908IlePhe: 1.908 ± 0.044	4.796IleGly: 4.796 ± 0.073	1.054IleHis: 1.054 ± 0.028	2.406IleIle: 2.406 ± 0.052	2.342IleLys: 2.342 ± 0.048	4.158IleLeu: 4.158 ± 0.069	0.893IleMet: 0.893 ± 0.033	2.127IleAsn: 2.127 ± 0.043	2.694IlePro: 2.694 ± 0.048	1.58IleGln: 1.58 ± 0.041	2.906IleArg: 2.906 ± 0.061	3.649IleSer: 3.649 ± 0.067	3.255IleThr: 3.255 ± 0.046	3.887IleVal: 3.887 ± 0.057	0.639IleTrp: 0.639 ± 0.028	1.44IleTyr: 1.44 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	4.742LysAla: 4.742 ± 0.088	0.282LysCys: 0.282 ± 0.018	2.181LysAsp: 2.181 ± 0.048	2.115LysGlu: 2.115 ± 0.044	1.46LysPhe: 1.46 ± 0.035	3.04LysGly: 3.04 ± 0.062	0.908LysHis: 0.908 ± 0.026	2.498LysIle: 2.498 ± 0.05	2.288LysLys: 2.288 ± 0.063	4.828LysLeu: 4.828 ± 0.073	1.214LysMet: 1.214 ± 0.035	1.651LysAsn: 1.651 ± 0.042	2.675LysPro: 2.675 ± 0.055	1.752LysGln: 1.752 ± 0.042	2.731LysArg: 2.731 ± 0.049	2.595LysSer: 2.595 ± 0.047	2.543LysThr: 2.543 ± 0.042	3.118LysVal: 3.118 ± 0.056	0.511LysTrp: 0.511 ± 0.019	1.017LysTyr: 1.017 ± 0.031	0.0LysXaa: 0.0 ± 0.0
Leu	11.344LeuAla: 11.344 ± 0.109	1.076LeuCys: 1.076 ± 0.032	5.544LeuAsp: 5.544 ± 0.07	5.153LeuGlu: 5.153 ± 0.079	3.614LeuPhe: 3.614 ± 0.068	7.797LeuGly: 7.797 ± 0.091	2.034LeuHis: 2.034 ± 0.045	5.43LeuIle: 5.43 ± 0.079	4.796LeuLys: 4.796 ± 0.071	10.541LeuLeu: 10.541 ± 0.134	2.523LeuMet: 2.523 ± 0.046	3.562LeuAsn: 3.562 ± 0.062	5.648LeuPro: 5.648 ± 0.077	3.745LeuGln: 3.745 ± 0.068	6.575LeuArg: 6.575 ± 0.086	7.083LeuSer: 7.083 ± 0.091	5.727LeuThr: 5.727 ± 0.073	6.726LeuVal: 6.726 ± 0.07	1.233LeuTrp: 1.233 ± 0.034	2.29LeuTyr: 2.29 ± 0.047	0.001LeuXaa: 0.001 ± 0.001
Met	2.482MetAla: 2.482 ± 0.042	0.189MetCys: 0.189 ± 0.013	1.12MetAsp: 1.12 ± 0.033	1.086MetGlu: 1.086 ± 0.028	0.83MetPhe: 0.83 ± 0.027	1.794MetGly: 1.794 ± 0.04	0.535MetHis: 0.535 ± 0.02	1.227MetIle: 1.227 ± 0.037	1.279MetLys: 1.279 ± 0.034	2.57MetLeu: 2.57 ± 0.052	0.672MetMet: 0.672 ± 0.028	0.956MetAsn: 0.956 ± 0.028	1.403MetPro: 1.403 ± 0.036	1.043MetGln: 1.043 ± 0.029	1.677MetArg: 1.677 ± 0.031	1.901MetSer: 1.901 ± 0.038	1.58MetThr: 1.58 ± 0.039	1.495MetVal: 1.495 ± 0.041	0.239MetTrp: 0.239 ± 0.018	0.463MetTyr: 0.463 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.77AsnAla: 3.77 ± 0.054	0.344AsnCys: 0.344 ± 0.019	1.761AsnAsp: 1.761 ± 0.044	1.663AsnGlu: 1.663 ± 0.039	1.408AsnPhe: 1.408 ± 0.039	3.003AsnGly: 3.003 ± 0.065	0.677AsnHis: 0.677 ± 0.021	1.901AsnIle: 1.901 ± 0.04	1.336AsnLys: 1.336 ± 0.039	3.278AsnLeu: 3.278 ± 0.054	0.716AsnMet: 0.716 ± 0.023	1.303AsnAsn: 1.303 ± 0.04	2.14AsnPro: 2.14 ± 0.048	1.158AsnGln: 1.158 ± 0.035	1.844AsnArg: 1.844 ± 0.046	1.919AsnSer: 1.919 ± 0.05	1.943AsnThr: 1.943 ± 0.047	2.459AsnVal: 2.459 ± 0.048	0.543AsnTrp: 0.543 ± 0.02	1.023AsnTyr: 1.023 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	5.403ProAla: 5.403 ± 0.096	0.313ProCys: 0.313 ± 0.017	2.876ProAsp: 2.876 ± 0.054	3.344ProGlu: 3.344 ± 0.05	1.807ProPhe: 1.807 ± 0.042	3.764ProGly: 3.764 ± 0.059	1.001ProHis: 1.001 ± 0.031	2.429ProIle: 2.429 ± 0.045	2.111ProLys: 2.111 ± 0.043	4.838ProLeu: 4.838 ± 0.059	1.296ProMet: 1.296 ± 0.035	1.674ProAsn: 1.674 ± 0.04	2.174ProPro: 2.174 ± 0.063	2.054ProGln: 2.054 ± 0.046	2.514ProArg: 2.514 ± 0.054	2.891ProSer: 2.891 ± 0.054	2.85ProThr: 2.85 ± 0.059	3.85ProVal: 3.85 ± 0.06	0.668ProTrp: 0.668 ± 0.03	1.238ProTyr: 1.238 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	4.233GlnAla: 4.233 ± 0.06	0.287GlnCys: 0.287 ± 0.017	1.626GlnAsp: 1.626 ± 0.039	1.683GlnGlu: 1.683 ± 0.04	1.397GlnPhe: 1.397 ± 0.039	2.545GlnGly: 2.545 ± 0.046	0.837GlnHis: 0.837 ± 0.025	2.217GlnIle: 2.217 ± 0.045	1.723GlnLys: 1.723 ± 0.046	4.09GlnLeu: 4.09 ± 0.066	1.029GlnMet: 1.029 ± 0.027	1.239GlnAsn: 1.239 ± 0.036	1.882GlnPro: 1.882 ± 0.043	1.87GlnGln: 1.87 ± 0.052	2.711GlnArg: 2.711 ± 0.056	2.285GlnSer: 2.285 ± 0.042	2.038GlnThr: 2.038 ± 0.043	2.534GlnVal: 2.534 ± 0.05	0.595GlnTrp: 0.595 ± 0.027	1.038GlnTyr: 1.038 ± 0.032	0.0GlnXaa: 0.0 ± 0.0
Arg	6.034ArgAla: 6.034 ± 0.084	0.545ArgCys: 0.545 ± 0.024	3.394ArgAsp: 3.394 ± 0.053	3.855ArgGlu: 3.855 ± 0.066	2.439ArgPhe: 2.439 ± 0.047	4.12ArgGly: 4.12 ± 0.068	1.338ArgHis: 1.338 ± 0.033	3.511ArgIle: 3.511 ± 0.052	2.577ArgLys: 2.577 ± 0.051	6.288ArgLeu: 6.288 ± 0.08	1.697ArgMet: 1.697 ± 0.035	2.038ArgAsn: 2.038 ± 0.038	2.471ArgPro: 2.471 ± 0.045	2.107ArgGln: 2.107 ± 0.047	3.764ArgArg: 3.764 ± 0.068	3.379ArgSer: 3.379 ± 0.054	2.892ArgThr: 2.892 ± 0.056	4.567ArgVal: 4.567 ± 0.071	0.984ArgTrp: 0.984 ± 0.031	2.071ArgTyr: 2.071 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	6.892SerAla: 6.892 ± 0.082	0.565SerCys: 0.565 ± 0.025	3.126SerAsp: 3.126 ± 0.055	3.021SerGlu: 3.021 ± 0.053	2.419SerPhe: 2.419 ± 0.041	5.555SerGly: 5.555 ± 0.092	1.191SerHis: 1.191 ± 0.033	3.214SerIle: 3.214 ± 0.053	2.628SerLys: 2.628 ± 0.052	6.198SerLeu: 6.198 ± 0.076	1.473SerMet: 1.473 ± 0.044	2.171SerAsn: 2.171 ± 0.048	2.9SerPro: 2.9 ± 0.055	2.113SerGln: 2.113 ± 0.044	3.489SerArg: 3.489 ± 0.05	4.016SerSer: 4.016 ± 0.078	3.368SerThr: 3.368 ± 0.063	4.448SerVal: 4.448 ± 0.063	0.886SerTrp: 0.886 ± 0.03	1.731SerTyr: 1.731 ± 0.042	0.0SerXaa: 0.0 ± 0.0
Thr	6.019ThrAla: 6.019 ± 0.078	0.483ThrCys: 0.483 ± 0.03	2.695ThrAsp: 2.695 ± 0.056	2.726ThrGlu: 2.726 ± 0.049	2.026ThrPhe: 2.026 ± 0.046	4.772ThrGly: 4.772 ± 0.069	1.205ThrHis: 1.205 ± 0.035	2.726ThrIle: 2.726 ± 0.048	1.976ThrLys: 1.976 ± 0.046	6.383ThrLeu: 6.383 ± 0.068	1.132ThrMet: 1.132 ± 0.032	1.684ThrAsn: 1.684 ± 0.045	3.425ThrPro: 3.425 ± 0.061	2.229ThrGln: 2.229 ± 0.045	3.219ThrArg: 3.219 ± 0.05	3.196ThrSer: 3.196 ± 0.066	3.152ThrThr: 3.152 ± 0.059	4.095ThrVal: 4.095 ± 0.072	0.694ThrTrp: 0.694 ± 0.027	1.394ThrTyr: 1.394 ± 0.044	0.0ThrXaa: 0.0 ± 0.0
Val	7.89ValAla: 7.89 ± 0.09	0.657ValCys: 0.657 ± 0.027	4.074ValAsp: 4.074 ± 0.065	3.933ValGlu: 3.933 ± 0.071	2.609ValPhe: 2.609 ± 0.051	5.347ValGly: 5.347 ± 0.085	1.45ValHis: 1.45 ± 0.037	4.173ValIle: 4.173 ± 0.068	2.941ValLys: 2.941 ± 0.053	7.418ValLeu: 7.418 ± 0.09	1.813ValMet: 1.813 ± 0.042	2.548ValAsn: 2.548 ± 0.053	3.588ValPro: 3.588 ± 0.057	2.483ValGln: 2.483 ± 0.045	4.24ValArg: 4.24 ± 0.064	4.642ValSer: 4.642 ± 0.059	4.349ValThr: 4.349 ± 0.07	5.686ValVal: 5.686 ± 0.079	0.857ValTrp: 0.857 ± 0.024	1.657ValTyr: 1.657 ± 0.033	0.0ValXaa: 0.0 ± 0.0
Trp	1.167TrpAla: 1.167 ± 0.033	0.157TrpCys: 0.157 ± 0.012	0.671TrpAsp: 0.671 ± 0.025	0.532TrpGlu: 0.532 ± 0.021	0.564TrpPhe: 0.564 ± 0.022	0.928TrpGly: 0.928 ± 0.031	0.366TrpHis: 0.366 ± 0.017	0.774TrpIle: 0.774 ± 0.03	0.641TrpLys: 0.641 ± 0.026	1.746TrpLeu: 1.746 ± 0.042	0.411TrpMet: 0.411 ± 0.018	0.587TrpAsn: 0.587 ± 0.023	0.657TrpPro: 0.657 ± 0.025	0.621TrpGln: 0.621 ± 0.023	0.956TrpArg: 0.956 ± 0.029	0.86TrpSer: 0.86 ± 0.031	0.805TrpThr: 0.805 ± 0.028	0.918TrpVal: 0.918 ± 0.029	0.236TrpTrp: 0.236 ± 0.015	0.329TrpTyr: 0.329 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.777TyrAla: 2.777 ± 0.051	0.293TyrCys: 0.293 ± 0.017	1.528TyrAsp: 1.528 ± 0.053	1.427TyrGlu: 1.427 ± 0.035	1.175TyrPhe: 1.175 ± 0.029	2.24TyrGly: 2.24 ± 0.044	0.51TyrHis: 0.51 ± 0.021	1.159TyrIle: 1.159 ± 0.032	1.049TyrLys: 1.049 ± 0.034	2.716TyrLeu: 2.716 ± 0.051	0.529TyrMet: 0.529 ± 0.019	0.933TyrAsn: 0.933 ± 0.031	1.296TyrPro: 1.296 ± 0.031	1.087TyrGln: 1.087 ± 0.029	1.91TyrArg: 1.91 ± 0.041	1.676TyrSer: 1.676 ± 0.042	1.483TyrThr: 1.483 ± 0.039	1.825TyrVal: 1.825 ± 0.042	0.418TyrTrp: 0.418 ± 0.018	0.757TyrTyr: 0.757 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.001	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3581 proteins (1192750 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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