Amino acid dipepetide frequency for Hubei mosquito virus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.735AlaAla: 5.735 ± 2.286
0.0AlaCys: 0.0 ± 0.0
4.301AlaAsp: 4.301 ± 1.127
5.018AlaGlu: 5.018 ± 2.117
1.434AlaPhe: 1.434 ± 0.572
6.452AlaGly: 6.452 ± 3.42
0.717AlaHis: 0.717 ± 0.555
4.301AlaIle: 4.301 ± 1.98
7.168AlaLys: 7.168 ± 1.338
5.735AlaLeu: 5.735 ± 1.903
0.0AlaMet: 0.0 ± 0.0
5.018AlaAsn: 5.018 ± 2.117
8.602AlaPro: 8.602 ± 3.351
1.434AlaGln: 1.434 ± 0.481
5.735AlaArg: 5.735 ± 0.922
5.735AlaSer: 5.735 ± 2.671
6.452AlaThr: 6.452 ± 2.35
4.301AlaVal: 4.301 ± 0.92
2.151AlaTrp: 2.151 ± 1.06
1.434AlaTyr: 1.434 ± 1.109
0.0AlaXaa: 0.0 ± 0.0
Cys
0.717CysAla: 0.717 ± 0.555
0.0CysCys: 0.0 ± 0.0
0.717CysAsp: 0.717 ± 0.602
1.434CysGlu: 1.434 ± 1.109
0.0CysPhe: 0.0 ± 0.0
1.434CysGly: 1.434 ± 0.481
0.717CysHis: 0.717 ± 0.555
0.717CysIle: 0.717 ± 0.555
0.717CysLys: 0.717 ± 0.555
1.434CysLeu: 1.434 ± 0.481
0.0CysMet: 0.0 ± 0.0
0.717CysAsn: 0.717 ± 0.555
0.0CysPro: 0.0 ± 0.0
0.717CysGln: 0.717 ± 0.555
3.584CysArg: 3.584 ± 0.616
0.0CysSer: 0.0 ± 0.0
0.717CysThr: 0.717 ± 0.554
0.717CysVal: 0.717 ± 0.555
0.0CysTrp: 0.0 ± 0.0
0.717CysTyr: 0.717 ± 0.555
0.0CysXaa: 0.0 ± 0.0
Asp
4.301AspAla: 4.301 ± 1.715
1.434AspCys: 1.434 ± 0.481
2.867AspAsp: 2.867 ± 1.388
2.151AspGlu: 2.151 ± 0.13
3.584AspPhe: 3.584 ± 1.677
5.018AspGly: 5.018 ± 1.608
1.434AspHis: 1.434 ± 0.481
2.151AspIle: 2.151 ± 1.06
2.151AspLys: 2.151 ± 0.13
3.584AspLeu: 3.584 ± 0.773
0.0AspMet: 0.0 ± 0.0
0.0AspAsn: 0.0 ± 0.0
3.584AspPro: 3.584 ± 1.756
1.434AspGln: 1.434 ± 1.109
2.151AspArg: 2.151 ± 0.951
2.151AspSer: 2.151 ± 1.134
1.434AspThr: 1.434 ± 0.481
0.717AspVal: 0.717 ± 0.554
0.717AspTrp: 0.717 ± 0.602
0.717AspTyr: 0.717 ± 0.555
0.0AspXaa: 0.0 ± 0.0
Glu
2.867GluAla: 2.867 ± 1.448
2.867GluCys: 2.867 ± 0.568
1.434GluAsp: 1.434 ± 0.66
3.584GluGlu: 3.584 ± 0.367
3.584GluPhe: 3.584 ± 0.616
1.434GluGly: 1.434 ± 0.572
2.867GluHis: 2.867 ± 2.219
0.717GluIle: 0.717 ± 0.555
2.867GluLys: 2.867 ± 1.388
7.885GluLeu: 7.885 ± 1.691
0.0GluMet: 0.0 ± 0.0
0.717GluAsn: 0.717 ± 0.554
5.018GluPro: 5.018 ± 0.851
2.151GluGln: 2.151 ± 0.13
3.584GluArg: 3.584 ± 1.677
5.018GluSer: 5.018 ± 2.607
1.434GluThr: 1.434 ± 1.203
2.151GluVal: 2.151 ± 0.877
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
5.018PheAla: 5.018 ± 0.851
0.717PheCys: 0.717 ± 0.555
2.151PheAsp: 2.151 ± 1.664
0.717PheGlu: 0.717 ± 0.602
1.434PhePhe: 1.434 ± 1.203
2.867PheGly: 2.867 ± 0.568
1.434PheHis: 1.434 ± 1.108
0.717PheIle: 0.717 ± 0.602
0.717PheLys: 0.717 ± 0.602
2.867PheLeu: 2.867 ± 1.388
0.717PheMet: 0.717 ± 0.555
0.717PheAsn: 0.717 ± 0.555
2.151PhePro: 2.151 ± 0.951
1.434PheGln: 1.434 ± 0.572
0.0PheArg: 0.0 ± 0.0
2.867PheSer: 2.867 ± 0.725
2.151PheThr: 2.151 ± 1.134
4.301PheVal: 4.301 ± 2.765
0.0PheTrp: 0.0 ± 0.0
2.151PheTyr: 2.151 ± 1.134
0.0PheXaa: 0.0 ± 0.0
Gly
6.452GlyAla: 6.452 ± 0.906
0.0GlyCys: 0.0 ± 0.0
5.018GlyAsp: 5.018 ± 0.846
4.301GlyGlu: 4.301 ± 0.26
1.434GlyPhe: 1.434 ± 1.203
4.301GlyGly: 4.301 ± 1.98
2.151GlyHis: 2.151 ± 0.13
3.584GlyIle: 3.584 ± 0.773
5.018GlyLys: 5.018 ± 0.851
5.735GlyLeu: 5.735 ± 1.896
1.434GlyMet: 1.434 ± 1.109
2.867GlyAsn: 2.867 ± 0.461
5.735GlyPro: 5.735 ± 1.461
3.584GlyGln: 3.584 ± 1.303
7.885GlyArg: 7.885 ± 0.843
10.036GlySer: 10.036 ± 2.531
6.452GlyThr: 6.452 ± 1.226
6.452GlyVal: 6.452 ± 1.47
0.717GlyTrp: 0.717 ± 0.554
1.434GlyTyr: 1.434 ± 1.109
0.0GlyXaa: 0.0 ± 0.0
His
1.434HisAla: 1.434 ± 0.481
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.717HisPhe: 0.717 ± 0.555
2.151HisGly: 2.151 ± 0.877
0.717HisHis: 0.717 ± 0.554
0.717HisIle: 0.717 ± 0.555
1.434HisLys: 1.434 ± 0.481
3.584HisLeu: 3.584 ± 1.011
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.434HisPro: 1.434 ± 0.66
0.717HisGln: 0.717 ± 0.555
2.151HisArg: 2.151 ± 0.877
2.867HisSer: 2.867 ± 0.568
0.0HisThr: 0.0 ± 0.0
2.151HisVal: 2.151 ± 1.664
0.717HisTrp: 0.717 ± 0.555
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.867IleAla: 2.867 ± 1.388
0.0IleCys: 0.0 ± 0.0
2.867IleAsp: 2.867 ± 0.568
2.867IleGlu: 2.867 ± 2.219
2.151IlePhe: 2.151 ± 1.06
2.867IleGly: 2.867 ± 1.558
0.717IleHis: 0.717 ± 0.554
0.717IleIle: 0.717 ± 0.602
1.434IleLys: 1.434 ± 0.66
2.867IleLeu: 2.867 ± 1.692
0.717IleMet: 0.717 ± 0.602
1.434IleAsn: 1.434 ± 0.66
1.434IlePro: 1.434 ± 0.481
1.434IleGln: 1.434 ± 0.481
0.717IleArg: 0.717 ± 0.555
2.151IleSer: 2.151 ± 1.06
1.434IleThr: 1.434 ± 0.572
2.151IleVal: 2.151 ± 1.06
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
5.018LysAla: 5.018 ± 2.015
0.0LysCys: 0.0 ± 0.0
5.735LysAsp: 5.735 ± 0.683
2.867LysGlu: 2.867 ± 1.386
3.584LysPhe: 3.584 ± 0.773
6.452LysGly: 6.452 ± 2.631
0.0LysHis: 0.0 ± 0.0
0.0LysIle: 0.0 ± 0.0
2.867LysLys: 2.867 ± 0.568
5.735LysLeu: 5.735 ± 1.219
4.301LysMet: 4.301 ± 1.82
2.151LysAsn: 2.151 ± 0.13
5.735LysPro: 5.735 ± 1.903
3.584LysGln: 3.584 ± 1.326
2.867LysArg: 2.867 ± 1.558
1.434LysSer: 1.434 ± 1.203
0.717LysThr: 0.717 ± 0.555
1.434LysVal: 1.434 ± 0.572
0.717LysTrp: 0.717 ± 0.555
4.301LysTyr: 4.301 ± 1.667
0.0LysXaa: 0.0 ± 0.0
Leu
6.452LeuAla: 6.452 ± 1.626
0.717LeuCys: 0.717 ± 0.602
1.434LeuAsp: 1.434 ± 1.109
8.602LeuGlu: 8.602 ± 2.204
0.717LeuPhe: 0.717 ± 0.602
4.301LeuGly: 4.301 ± 0.82
0.717LeuHis: 0.717 ± 0.555
5.018LeuIle: 5.018 ± 2.221
2.151LeuLys: 2.151 ± 0.878
9.319LeuLeu: 9.319 ± 3.466
2.151LeuMet: 2.151 ± 1.134
2.867LeuAsn: 2.867 ± 1.143
5.018LeuPro: 5.018 ± 0.609
5.018LeuGln: 5.018 ± 0.609
5.018LeuArg: 5.018 ± 0.846
5.018LeuSer: 5.018 ± 1.351
4.301LeuThr: 4.301 ± 0.26
5.735LeuVal: 5.735 ± 1.461
0.0LeuTrp: 0.0 ± 0.0
5.018LeuTyr: 5.018 ± 1.388
0.0LeuXaa: 0.0 ± 0.0
Met
0.717MetAla: 0.717 ± 0.554
0.717MetCys: 0.717 ± 0.555
0.0MetAsp: 0.0 ± 0.0
1.434MetGlu: 1.434 ± 0.481
2.867MetPhe: 2.867 ± 0.568
0.717MetGly: 0.717 ± 0.555
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
2.151MetLys: 2.151 ± 0.878
0.717MetLeu: 0.717 ± 0.555
0.717MetMet: 0.717 ± 0.555
0.717MetAsn: 0.717 ± 0.555
0.0MetPro: 0.0 ± 0.0
0.717MetGln: 0.717 ± 0.602
2.151MetArg: 2.151 ± 1.134
3.584MetSer: 3.584 ± 1.303
3.584MetThr: 3.584 ± 1.756
2.867MetVal: 2.867 ± 1.558
0.0MetTrp: 0.0 ± 0.0
0.717MetTyr: 0.717 ± 0.555
0.0MetXaa: 0.0 ± 0.0
Asn
2.867AsnAla: 2.867 ± 1.143
0.717AsnCys: 0.717 ± 0.555
0.717AsnAsp: 0.717 ± 0.555
1.434AsnGlu: 1.434 ± 1.109
0.0AsnPhe: 0.0 ± 0.0
2.151AsnGly: 2.151 ± 0.878
0.0AsnHis: 0.0 ± 0.0
0.0AsnIle: 0.0 ± 0.0
2.867AsnLys: 2.867 ± 0.568
2.151AsnLeu: 2.151 ± 0.951
0.717AsnMet: 0.717 ± 0.555
0.0AsnAsn: 0.0 ± 0.0
6.452AsnPro: 6.452 ± 1.867
0.717AsnGln: 0.717 ± 0.555
2.867AsnArg: 2.867 ± 0.962
3.584AsnSer: 3.584 ± 1.469
4.301AsnThr: 4.301 ± 1.127
2.867AsnVal: 2.867 ± 1.593
2.151AsnTrp: 2.151 ± 1.805
0.717AsnTyr: 0.717 ± 0.555
0.0AsnXaa: 0.0 ± 0.0
Pro
9.319ProAla: 9.319 ± 5.573
0.0ProCys: 0.0 ± 0.0
0.0ProAsp: 0.0 ± 0.0
3.584ProGlu: 3.584 ± 0.367
1.434ProPhe: 1.434 ± 0.572
9.319ProGly: 9.319 ± 1.919
1.434ProHis: 1.434 ± 0.572
1.434ProIle: 1.434 ± 1.109
4.301ProLys: 4.301 ± 2.515
3.584ProLeu: 3.584 ± 1.115
2.151ProMet: 2.151 ± 0.878
2.151ProAsn: 2.151 ± 1.035
2.867ProPro: 2.867 ± 1.448
2.867ProGln: 2.867 ± 1.448
10.036ProArg: 10.036 ± 4.411
4.301ProSer: 4.301 ± 1.264
4.301ProThr: 4.301 ± 3.324
5.018ProVal: 5.018 ± 1.822
1.434ProTrp: 1.434 ± 1.109
0.717ProTyr: 0.717 ± 0.602
0.0ProXaa: 0.0 ± 0.0
Gln
2.867GlnAla: 2.867 ± 1.448
2.151GlnCys: 2.151 ± 1.664
0.0GlnAsp: 0.0 ± 0.0
1.434GlnGlu: 1.434 ± 0.572
0.0GlnPhe: 0.0 ± 0.0
2.151GlnGly: 2.151 ± 0.13
1.434GlnHis: 1.434 ± 1.108
0.0GlnIle: 0.0 ± 0.0
0.717GlnLys: 0.717 ± 0.602
5.735GlnLeu: 5.735 ± 1.136
1.434GlnMet: 1.434 ± 0.922
0.717GlnAsn: 0.717 ± 0.555
2.867GlnPro: 2.867 ± 0.461
0.717GlnGln: 0.717 ± 0.554
5.735GlnArg: 5.735 ± 0.683
2.151GlnSer: 2.151 ± 1.035
1.434GlnThr: 1.434 ± 0.481
0.717GlnVal: 0.717 ± 0.555
1.434GlnTrp: 1.434 ± 0.481
2.151GlnTyr: 2.151 ± 0.878
0.0GlnXaa: 0.0 ± 0.0
Arg
9.319ArgAla: 9.319 ± 2.289
0.717ArgCys: 0.717 ± 0.555
2.151ArgAsp: 2.151 ± 0.13
0.717ArgGlu: 0.717 ± 0.555
2.867ArgPhe: 2.867 ± 1.593
7.885ArgGly: 7.885 ± 2.574
2.151ArgHis: 2.151 ± 1.664
1.434ArgIle: 1.434 ± 0.481
5.018ArgLys: 5.018 ± 2.117
6.452ArgLeu: 6.452 ± 2.052
3.584ArgMet: 3.584 ± 1.115
6.452ArgAsn: 6.452 ± 1.681
6.452ArgPro: 6.452 ± 2.35
2.151ArgGln: 2.151 ± 0.13
6.452ArgArg: 6.452 ± 0.906
5.735ArgSer: 5.735 ± 2.408
5.735ArgThr: 5.735 ± 2.671
4.301ArgVal: 4.301 ± 0.92
0.0ArgTrp: 0.0 ± 0.0
3.584ArgTyr: 3.584 ± 2.085
0.0ArgXaa: 0.0 ± 0.0
Ser
7.168SerAla: 7.168 ± 2.022
1.434SerCys: 1.434 ± 1.109
4.301SerAsp: 4.301 ± 1.928
2.151SerGlu: 2.151 ± 1.06
1.434SerPhe: 1.434 ± 0.572
11.47SerGly: 11.47 ± 2.931
0.717SerHis: 0.717 ± 0.554
2.151SerIle: 2.151 ± 0.13
5.735SerLys: 5.735 ± 1.766
7.168SerLeu: 7.168 ± 2.413
2.151SerMet: 2.151 ± 0.13
1.434SerAsn: 1.434 ± 1.203
6.452SerPro: 6.452 ± 2.854
2.867SerGln: 2.867 ± 1.386
5.018SerArg: 5.018 ± 2.117
9.319SerSer: 9.319 ± 1.93
6.452SerThr: 6.452 ± 0.906
4.301SerVal: 4.301 ± 1.133
1.434SerTrp: 1.434 ± 0.481
1.434SerTyr: 1.434 ± 0.66
0.0SerXaa: 0.0 ± 0.0
Thr
4.301ThrAla: 4.301 ± 2.463
0.0ThrCys: 0.0 ± 0.0
2.151ThrAsp: 2.151 ± 1.134
0.0ThrGlu: 0.0 ± 0.0
3.584ThrPhe: 3.584 ± 1.326
6.452ThrGly: 6.452 ± 3.047
2.151ThrHis: 2.151 ± 1.06
2.867ThrIle: 2.867 ± 0.461
7.168ThrLys: 7.168 ± 1.662
2.151ThrLeu: 2.151 ± 1.035
1.434ThrMet: 1.434 ± 0.66
4.301ThrAsn: 4.301 ± 1.715
2.867ThrPro: 2.867 ± 1.448
1.434ThrGln: 1.434 ± 0.572
5.735ThrArg: 5.735 ± 1.219
6.452ThrSer: 6.452 ± 1.75
3.584ThrThr: 3.584 ± 0.616
6.452ThrVal: 6.452 ± 3.42
0.0ThrTrp: 0.0 ± 0.0
0.717ThrTyr: 0.717 ± 0.555
0.0ThrXaa: 0.0 ± 0.0
Val
4.301ValAla: 4.301 ± 1.928
2.867ValCys: 2.867 ± 1.386
2.151ValAsp: 2.151 ± 0.13
5.018ValGlu: 5.018 ± 0.851
3.584ValPhe: 3.584 ± 1.303
5.018ValGly: 5.018 ± 1.266
0.717ValHis: 0.717 ± 0.554
1.434ValIle: 1.434 ± 0.66
2.867ValLys: 2.867 ± 1.692
1.434ValLeu: 1.434 ± 0.481
0.717ValMet: 0.717 ± 0.555
3.584ValAsn: 3.584 ± 1.326
2.151ValPro: 2.151 ± 0.877
2.151ValGln: 2.151 ± 1.035
8.602ValArg: 8.602 ± 2.122
8.602ValSer: 8.602 ± 2.582
3.584ValThr: 3.584 ± 3.008
4.301ValVal: 4.301 ± 0.26
0.0ValTrp: 0.0 ± 0.0
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.717TrpAsp: 0.717 ± 0.602
0.0TrpGlu: 0.0 ± 0.0
0.717TrpPhe: 0.717 ± 0.555
0.717TrpGly: 0.717 ± 0.555
0.0TrpHis: 0.0 ± 0.0
0.717TrpIle: 0.717 ± 0.555
1.434TrpLys: 1.434 ± 1.108
0.717TrpLeu: 0.717 ± 0.555
0.717TrpMet: 0.717 ± 0.475
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.434TrpGln: 1.434 ± 0.572
0.717TrpArg: 0.717 ± 0.602
1.434TrpSer: 1.434 ± 0.66
1.434TrpThr: 1.434 ± 0.66
0.717TrpVal: 0.717 ± 0.555
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.717TyrCys: 0.717 ± 0.602
2.867TyrAsp: 2.867 ± 1.388
2.867TyrGlu: 2.867 ± 0.725
0.0TyrPhe: 0.0 ± 0.0
1.434TyrGly: 1.434 ± 1.109
0.717TyrHis: 0.717 ± 0.555
2.151TyrIle: 2.151 ± 1.06
0.717TyrLys: 0.717 ± 0.554
0.717TyrLeu: 0.717 ± 0.555
0.717TyrMet: 0.717 ± 0.555
1.434TyrAsn: 1.434 ± 0.481
1.434TyrPro: 1.434 ± 1.109
0.0TyrGln: 0.0 ± 0.0
2.151TyrArg: 2.151 ± 0.13
2.151TyrSer: 2.151 ± 1.134
4.301TyrThr: 4.301 ± 2.467
1.434TyrVal: 1.434 ± 0.66
0.0TyrTrp: 0.0 ± 0.0
1.434TyrTyr: 1.434 ± 0.572
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1396 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski