Amino acid dipepetide frequency for Mesorhizobium alhagi CCNWXJ12-2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.297AlaAla: 17.297 ± 0.144	1.034AlaCys: 1.034 ± 0.025	6.866AlaAsp: 6.866 ± 0.065	8.138AlaGlu: 8.138 ± 0.086	4.678AlaPhe: 4.678 ± 0.054	11.055AlaGly: 11.055 ± 0.089	2.108AlaHis: 2.108 ± 0.034	6.852AlaIle: 6.852 ± 0.067	4.278AlaLys: 4.278 ± 0.054	12.68AlaLeu: 12.68 ± 0.106	3.535AlaMet: 3.535 ± 0.047	3.079AlaAsn: 3.079 ± 0.047	5.176AlaPro: 5.176 ± 0.072	3.423AlaGln: 3.423 ± 0.045	8.299AlaArg: 8.299 ± 0.077	6.495AlaSer: 6.495 ± 0.068	5.923AlaThr: 5.923 ± 0.073	8.822AlaVal: 8.822 ± 0.08	1.498AlaTrp: 1.498 ± 0.032	2.568AlaTyr: 2.568 ± 0.039	0.0AlaXaa: 0.0 ± 0.0
Cys	0.935CysAla: 0.935 ± 0.024	0.119CysCys: 0.119 ± 0.008	0.501CysAsp: 0.501 ± 0.017	0.444CysGlu: 0.444 ± 0.015	0.339CysPhe: 0.339 ± 0.013	0.891CysGly: 0.891 ± 0.025	0.234CysHis: 0.234 ± 0.012	0.408CysIle: 0.408 ± 0.016	0.195CysLys: 0.195 ± 0.01	0.747CysLeu: 0.747 ± 0.018	0.179CysMet: 0.179 ± 0.011	0.207CysAsn: 0.207 ± 0.01	0.433CysPro: 0.433 ± 0.018	0.213CysGln: 0.213 ± 0.012	0.648CysArg: 0.648 ± 0.022	0.486CysSer: 0.486 ± 0.017	0.411CysThr: 0.411 ± 0.014	0.584CysVal: 0.584 ± 0.018	0.125CysTrp: 0.125 ± 0.008	0.201CysTyr: 0.201 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	6.624AspAla: 6.624 ± 0.063	0.496AspCys: 0.496 ± 0.018	3.135AspAsp: 3.135 ± 0.051	3.702AspGlu: 3.702 ± 0.047	2.337AspPhe: 2.337 ± 0.038	5.251AspGly: 5.251 ± 0.069	1.212AspHis: 1.212 ± 0.025	3.228AspIle: 3.228 ± 0.05	1.679AspLys: 1.679 ± 0.035	5.666AspLeu: 5.666 ± 0.061	1.404AspMet: 1.404 ± 0.028	1.37AspAsn: 1.37 ± 0.03	3.406AspPro: 3.406 ± 0.043	1.63AspGln: 1.63 ± 0.029	4.434AspArg: 4.434 ± 0.053	2.227AspSer: 2.227 ± 0.04	2.503AspThr: 2.503 ± 0.041	4.044AspVal: 4.044 ± 0.045	0.933AspTrp: 0.933 ± 0.024	1.42AspTyr: 1.42 ± 0.028	0.0AspXaa: 0.0 ± 0.0
Glu	7.929GluAla: 7.929 ± 0.08	0.384GluCys: 0.384 ± 0.014	2.75GluAsp: 2.75 ± 0.038	3.463GluGlu: 3.463 ± 0.054	2.056GluPhe: 2.056 ± 0.029	4.446GluGly: 4.446 ± 0.05	1.209GluHis: 1.209 ± 0.03	3.949GluIle: 3.949 ± 0.049	2.702GluLys: 2.702 ± 0.04	5.611GluLeu: 5.611 ± 0.061	1.652GluMet: 1.652 ± 0.028	1.83GluAsn: 1.83 ± 0.031	2.972GluPro: 2.972 ± 0.046	2.123GluGln: 2.123 ± 0.038	5.148GluArg: 5.148 ± 0.062	2.475GluSer: 2.475 ± 0.038	3.606GluThr: 3.606 ± 0.043	3.82GluVal: 3.82 ± 0.048	0.77GluTrp: 0.77 ± 0.02	1.062GluTyr: 1.062 ± 0.025	0.0GluXaa: 0.0 ± 0.0
Phe	4.729PheAla: 4.729 ± 0.052	0.385PheCys: 0.385 ± 0.016	2.788PheAsp: 2.788 ± 0.037	2.366PheGlu: 2.366 ± 0.038	1.539PhePhe: 1.539 ± 0.033	3.937PheGly: 3.937 ± 0.059	0.763PheHis: 0.763 ± 0.022	1.845PheIle: 1.845 ± 0.031	1.056PheLys: 1.056 ± 0.022	3.612PheLeu: 3.612 ± 0.051	0.868PheMet: 0.868 ± 0.022	1.073PheAsn: 1.073 ± 0.023	1.707PhePro: 1.707 ± 0.033	1.084PheGln: 1.084 ± 0.023	2.439PheArg: 2.439 ± 0.039	2.528PheSer: 2.528 ± 0.039	1.922PheThr: 1.922 ± 0.03	3.008PheVal: 3.008 ± 0.039	0.616PheTrp: 0.616 ± 0.018	0.92PheTyr: 0.92 ± 0.023	0.0PheXaa: 0.0 ± 0.0
Gly	9.027GlyAla: 9.027 ± 0.087	0.826GlyCys: 0.826 ± 0.022	4.58GlyAsp: 4.58 ± 0.055	5.148GlyGlu: 5.148 ± 0.054	3.77GlyPhe: 3.77 ± 0.045	7.658GlyGly: 7.658 ± 0.108	1.877GlyHis: 1.877 ± 0.036	4.796GlyIle: 4.796 ± 0.053	3.467GlyLys: 3.467 ± 0.048	8.521GlyLeu: 8.521 ± 0.069	2.433GlyMet: 2.433 ± 0.039	2.445GlyAsn: 2.445 ± 0.061	3.464GlyPro: 3.464 ± 0.039	2.716GlyGln: 2.716 ± 0.038	6.146GlyArg: 6.146 ± 0.059	4.983GlySer: 4.983 ± 0.066	4.47GlyThr: 4.47 ± 0.094	6.081GlyVal: 6.081 ± 0.058	1.376GlyTrp: 1.376 ± 0.028	2.248GlyTyr: 2.248 ± 0.035	0.0GlyXaa: 0.0 ± 0.0
His	2.311HisAla: 2.311 ± 0.036	0.227HisCys: 0.227 ± 0.011	1.212HisAsp: 1.212 ± 0.023	1.107HisGlu: 1.107 ± 0.026	0.881HisPhe: 0.881 ± 0.021	1.94HisGly: 1.94 ± 0.031	0.575HisHis: 0.575 ± 0.021	0.972HisIle: 0.972 ± 0.021	0.495HisLys: 0.495 ± 0.015	1.981HisLeu: 1.981 ± 0.034	0.509HisMet: 0.509 ± 0.017	0.478HisAsn: 0.478 ± 0.017	1.252HisPro: 1.252 ± 0.028	0.593HisGln: 0.593 ± 0.02	1.4HisArg: 1.4 ± 0.033	1.001HisSer: 1.001 ± 0.022	0.813HisThr: 0.813 ± 0.019	1.461HisVal: 1.461 ± 0.026	0.341HisTrp: 0.341 ± 0.013	0.56HisTyr: 0.56 ± 0.016	0.0HisXaa: 0.0 ± 0.0
Ile	7.691IleAla: 7.691 ± 0.066	0.518IleCys: 0.518 ± 0.016	3.688IleAsp: 3.688 ± 0.049	3.76IleGlu: 3.76 ± 0.042	1.917IlePhe: 1.917 ± 0.032	5.175IleGly: 5.175 ± 0.058	0.938IleHis: 0.938 ± 0.024	2.498IleIle: 2.498 ± 0.039	1.458IleLys: 1.458 ± 0.027	4.639IleLeu: 4.639 ± 0.06	1.097IleMet: 1.097 ± 0.025	1.435IleAsn: 1.435 ± 0.033	2.4IlePro: 2.4 ± 0.037	1.19IleGln: 1.19 ± 0.024	3.497IleArg: 3.497 ± 0.038	3.156IleSer: 3.156 ± 0.044	2.631IleThr: 2.631 ± 0.047	4.736IleVal: 4.736 ± 0.058	0.622IleTrp: 0.622 ± 0.018	1.163IleTyr: 1.163 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	4.507LysAla: 4.507 ± 0.06	0.184LysCys: 0.184 ± 0.011	1.729LysAsp: 1.729 ± 0.036	1.795LysGlu: 1.795 ± 0.032	1.038LysPhe: 1.038 ± 0.024	2.61LysGly: 2.61 ± 0.043	0.663LysHis: 0.663 ± 0.021	1.917LysIle: 1.917 ± 0.035	1.532LysLys: 1.532 ± 0.035	3.472LysLeu: 3.472 ± 0.043	0.843LysMet: 0.843 ± 0.021	0.953LysAsn: 0.953 ± 0.023	2.257LysPro: 2.257 ± 0.034	1.05LysGln: 1.05 ± 0.022	2.607LysArg: 2.607 ± 0.042	2.024LysSer: 2.024 ± 0.037	2.006LysThr: 2.006 ± 0.035	2.351LysVal: 2.351 ± 0.04	0.446LysTrp: 0.446 ± 0.022	0.666LysTyr: 0.666 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	13.327LeuAla: 13.327 ± 0.107	0.82LeuCys: 0.82 ± 0.021	5.834LeuAsp: 5.834 ± 0.055	5.412LeuGlu: 5.412 ± 0.055	3.756LeuPhe: 3.756 ± 0.055	7.952LeuGly: 7.952 ± 0.074	1.83LeuHis: 1.83 ± 0.035	5.035LeuIle: 5.035 ± 0.061	3.634LeuLys: 3.634 ± 0.044	8.999LeuLeu: 8.999 ± 0.096	2.253LeuMet: 2.253 ± 0.033	2.542LeuAsn: 2.542 ± 0.039	5.278LeuPro: 5.278 ± 0.056	2.647LeuGln: 2.647 ± 0.039	6.514LeuArg: 6.514 ± 0.067	6.403LeuSer: 6.403 ± 0.073	5.179LeuThr: 5.179 ± 0.052	7.334LeuVal: 7.334 ± 0.074	1.131LeuTrp: 1.131 ± 0.027	2.014LeuTyr: 2.014 ± 0.037	0.0LeuXaa: 0.0 ± 0.0
Met	3.227MetAla: 3.227 ± 0.038	0.145MetCys: 0.145 ± 0.008	1.16MetAsp: 1.16 ± 0.026	1.168MetGlu: 1.168 ± 0.027	0.788MetPhe: 0.788 ± 0.022	1.734MetGly: 1.734 ± 0.034	0.468MetHis: 0.468 ± 0.016	1.452MetIle: 1.452 ± 0.028	1.121MetLys: 1.121 ± 0.023	2.594MetLeu: 2.594 ± 0.042	0.72MetMet: 0.72 ± 0.019	0.863MetAsn: 0.863 ± 0.024	1.559MetPro: 1.559 ± 0.028	0.797MetGln: 0.797 ± 0.019	1.884MetArg: 1.884 ± 0.036	1.649MetSer: 1.649 ± 0.03	1.782MetThr: 1.782 ± 0.027	1.732MetVal: 1.732 ± 0.03	0.228MetTrp: 0.228 ± 0.01	0.311MetTyr: 0.311 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.291AsnAla: 3.291 ± 0.049	0.254AsnCys: 0.254 ± 0.013	1.557AsnAsp: 1.557 ± 0.035	1.407AsnGlu: 1.407 ± 0.027	1.064AsnPhe: 1.064 ± 0.028	2.535AsnGly: 2.535 ± 0.059	0.51AsnHis: 0.51 ± 0.017	1.464AsnIle: 1.464 ± 0.034	0.699AsnLys: 0.699 ± 0.018	2.575AsnLeu: 2.575 ± 0.041	0.639AsnMet: 0.639 ± 0.018	0.753AsnAsn: 0.753 ± 0.031	1.886AsnPro: 1.886 ± 0.035	0.758AsnGln: 0.758 ± 0.023	1.903AsnArg: 1.903 ± 0.034	1.401AsnSer: 1.401 ± 0.03	1.316AsnThr: 1.316 ± 0.041	1.987AsnVal: 1.987 ± 0.037	0.463AsnTrp: 0.463 ± 0.016	0.66AsnTyr: 0.66 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	6.238ProAla: 6.238 ± 0.067	0.317ProCys: 0.317 ± 0.015	3.61ProAsp: 3.61 ± 0.043	3.776ProGlu: 3.776 ± 0.048	2.04ProPhe: 2.04 ± 0.038	4.351ProGly: 4.351 ± 0.057	1.072ProHis: 1.072 ± 0.023	2.334ProIle: 2.334 ± 0.034	1.832ProLys: 1.832 ± 0.029	4.584ProLeu: 4.584 ± 0.056	1.148ProMet: 1.148 ± 0.025	1.384ProAsn: 1.384 ± 0.026	2.481ProPro: 2.481 ± 0.049	1.568ProGln: 1.568 ± 0.03	2.86ProArg: 2.86 ± 0.042	2.745ProSer: 2.745 ± 0.037	2.375ProThr: 2.375 ± 0.035	4.134ProVal: 4.134 ± 0.049	0.696ProTrp: 0.696 ± 0.018	1.163ProTyr: 1.163 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	3.8GlnAla: 3.8 ± 0.049	0.194GlnCys: 0.194 ± 0.009	1.4GlnAsp: 1.4 ± 0.03	1.543GlnGlu: 1.543 ± 0.032	1.091GlnPhe: 1.091 ± 0.023	2.174GlnGly: 2.174 ± 0.037	0.589GlnHis: 0.589 ± 0.018	1.777GlnIle: 1.777 ± 0.035	1.139GlnLys: 1.139 ± 0.025	2.724GlnLeu: 2.724 ± 0.043	0.88GlnMet: 0.88 ± 0.022	0.87GlnAsn: 0.87 ± 0.023	1.7GlnPro: 1.7 ± 0.031	1.101GlnGln: 1.101 ± 0.031	2.268GlnArg: 2.268 ± 0.036	1.737GlnSer: 1.737 ± 0.028	1.61GlnThr: 1.61 ± 0.031	2.002GlnVal: 2.002 ± 0.032	0.4GlnTrp: 0.4 ± 0.014	0.578GlnTyr: 0.578 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	7.577ArgAla: 7.577 ± 0.069	0.523ArgCys: 0.523 ± 0.017	4.036ArgAsp: 4.036 ± 0.048	4.341ArgGlu: 4.341 ± 0.053	2.949ArgPhe: 2.949 ± 0.042	4.813ArgGly: 4.813 ± 0.06	1.768ArgHis: 1.768 ± 0.032	4.097ArgIle: 4.097 ± 0.053	2.624ArgLys: 2.624 ± 0.041	7.685ArgLeu: 7.685 ± 0.072	1.868ArgMet: 1.868 ± 0.029	2.025ArgAsn: 2.025 ± 0.032	3.495ArgPro: 3.495 ± 0.048	2.637ArgGln: 2.637 ± 0.047	5.781ArgArg: 5.781 ± 0.074	3.972ArgSer: 3.972 ± 0.045	3.424ArgThr: 3.424 ± 0.047	4.425ArgVal: 4.425 ± 0.052	0.961ArgTrp: 0.961 ± 0.023	1.676ArgTyr: 1.676 ± 0.033	0.0ArgXaa: 0.0 ± 0.0
Ser	6.372SerAla: 6.372 ± 0.063	0.457SerCys: 0.457 ± 0.018	3.053SerAsp: 3.053 ± 0.043	3.045SerGlu: 3.045 ± 0.035	2.415SerPhe: 2.415 ± 0.036	5.876SerGly: 5.876 ± 0.086	1.166SerHis: 1.166 ± 0.021	2.949SerIle: 2.949 ± 0.044	1.702SerLys: 1.702 ± 0.031	5.405SerLeu: 5.405 ± 0.059	1.441SerMet: 1.441 ± 0.026	1.438SerAsn: 1.438 ± 0.035	2.886SerPro: 2.886 ± 0.039	1.592SerGln: 1.592 ± 0.028	3.843SerArg: 3.843 ± 0.051	3.047SerSer: 3.047 ± 0.046	2.702SerThr: 2.702 ± 0.05	4.103SerVal: 4.103 ± 0.047	0.76SerTrp: 0.76 ± 0.021	1.281SerTyr: 1.281 ± 0.028	0.0SerXaa: 0.0 ± 0.0
Thr	6.138ThrAla: 6.138 ± 0.071	0.396ThrCys: 0.396 ± 0.016	2.663ThrAsp: 2.663 ± 0.045	2.731ThrGlu: 2.731 ± 0.038	2.059ThrPhe: 2.059 ± 0.038	5.081ThrGly: 5.081 ± 0.084	0.994ThrHis: 0.994 ± 0.023	3.087ThrIle: 3.087 ± 0.062	1.513ThrLys: 1.513 ± 0.029	5.363ThrLeu: 5.363 ± 0.064	1.255ThrMet: 1.255 ± 0.027	1.307ThrAsn: 1.307 ± 0.033	2.958ThrPro: 2.958 ± 0.036	1.297ThrGln: 1.297 ± 0.029	3.123ThrArg: 3.123 ± 0.037	2.714ThrSer: 2.714 ± 0.04	2.752ThrThr: 2.752 ± 0.059	4.341ThrVal: 4.341 ± 0.057	0.646ThrTrp: 0.646 ± 0.018	1.141ThrTyr: 1.141 ± 0.031	0.0ThrXaa: 0.0 ± 0.0
Val	9.108ValAla: 9.108 ± 0.072	0.63ValCys: 0.63 ± 0.015	4.098ValAsp: 4.098 ± 0.049	4.758ValGlu: 4.758 ± 0.058	2.957ValPhe: 2.957 ± 0.043	5.605ValGly: 5.605 ± 0.062	1.362ValHis: 1.362 ± 0.029	3.965ValIle: 3.965 ± 0.048	2.377ValLys: 2.377 ± 0.036	7.156ValLeu: 7.156 ± 0.064	1.838ValMet: 1.838 ± 0.034	2.002ValAsn: 2.002 ± 0.048	3.558ValPro: 3.558 ± 0.048	1.931ValGln: 1.931 ± 0.031	4.921ValArg: 4.921 ± 0.057	4.423ValSer: 4.423 ± 0.055	4.295ValThr: 4.295 ± 0.06	5.802ValVal: 5.802 ± 0.064	0.942ValTrp: 0.942 ± 0.022	1.44ValTyr: 1.44 ± 0.03	0.0ValXaa: 0.0 ± 0.0
Trp	1.282TrpAla: 1.282 ± 0.027	0.141TrpCys: 0.141 ± 0.009	0.616TrpAsp: 0.616 ± 0.015	0.588TrpGlu: 0.588 ± 0.019	0.564TrpPhe: 0.564 ± 0.015	0.876TrpGly: 0.876 ± 0.023	0.318TrpHis: 0.318 ± 0.012	0.666TrpIle: 0.666 ± 0.019	0.518TrpLys: 0.518 ± 0.016	1.679TrpLeu: 1.679 ± 0.035	0.384TrpMet: 0.384 ± 0.015	0.479TrpAsn: 0.479 ± 0.015	0.758TrpPro: 0.758 ± 0.023	0.567TrpGln: 0.567 ± 0.017	1.163TrpArg: 1.163 ± 0.025	0.845TrpSer: 0.845 ± 0.02	0.792TrpThr: 0.792 ± 0.018	0.781TrpVal: 0.781 ± 0.018	0.223TrpTrp: 0.223 ± 0.01	0.289TrpTyr: 0.289 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.394TyrAla: 2.394 ± 0.037	0.247TyrCys: 0.247 ± 0.011	1.426TyrAsp: 1.426 ± 0.026	1.266TyrGlu: 1.266 ± 0.026	0.95TyrPhe: 0.95 ± 0.02	2.071TyrGly: 2.071 ± 0.034	0.45TyrHis: 0.45 ± 0.014	0.92TyrIle: 0.92 ± 0.021	0.63TyrLys: 0.63 ± 0.018	2.2TyrLeu: 2.2 ± 0.039	0.437TyrMet: 0.437 ± 0.015	0.588TyrAsn: 0.588 ± 0.016	1.082TyrPro: 1.082 ± 0.027	0.662TyrGln: 0.662 ± 0.019	1.797TyrArg: 1.797 ± 0.031	1.223TyrSer: 1.223 ± 0.029	1.047TyrThr: 1.047 ± 0.024	1.617TyrVal: 1.617 ± 0.03	0.35TyrTrp: 0.35 ± 0.014	0.557TyrTyr: 0.557 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 7195 proteins (1987422 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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