Amino acid dipepetide frequency for Sanxia permutotetra-like virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.164AlaAla: 6.164 ± 0.647
0.0AlaCys: 0.0 ± 0.0
4.11AlaAsp: 4.11 ± 1.135
2.74AlaGlu: 2.74 ± 1.408
1.37AlaPhe: 1.37 ± 0.793
4.11AlaGly: 4.11 ± 1.529
0.685AlaHis: 0.685 ± 0.352
6.849AlaIle: 6.849 ± 1.25
12.329AlaLys: 12.329 ± 1.989
4.795AlaLeu: 4.795 ± 0.147
2.055AlaMet: 2.055 ± 1.056
2.74AlaAsn: 2.74 ± 2.204
3.425AlaPro: 3.425 ± 0.625
4.11AlaGln: 4.11 ± 1.135
2.74AlaArg: 2.74 ± 0.68
5.479AlaSer: 5.479 ± 2.545
3.425AlaThr: 3.425 ± 0.94
5.479AlaVal: 5.479 ± 1.784
1.37AlaTrp: 1.37 ± 0.704
2.74AlaTyr: 2.74 ± 1.408
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.685CysAsp: 0.685 ± 1.041
1.37CysGlu: 1.37 ± 1.675
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.685CysHis: 0.685 ± 0.352
0.0CysIle: 0.0 ± 0.0
0.685CysLys: 0.685 ± 0.352
1.37CysLeu: 1.37 ± 0.704
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.685CysPro: 0.685 ± 0.352
0.685CysGln: 0.685 ± 0.352
0.0CysArg: 0.0 ± 0.0
0.685CysSer: 0.685 ± 1.041
0.685CysThr: 0.685 ± 0.352
0.685CysVal: 0.685 ± 1.135
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.74AspAla: 2.74 ± 1.408
0.0AspCys: 0.0 ± 0.0
2.74AspAsp: 2.74 ± 0.783
3.425AspGlu: 3.425 ± 0.94
4.11AspPhe: 4.11 ± 1.135
4.795AspGly: 4.795 ± 2.189
0.0AspHis: 0.0 ± 0.0
2.055AspIle: 2.055 ± 0.65
2.74AspLys: 2.74 ± 1.586
4.795AspLeu: 4.795 ± 1.283
2.055AspMet: 2.055 ± 1.056
2.74AspAsn: 2.74 ± 1.586
4.11AspPro: 4.11 ± 1.135
1.37AspGln: 1.37 ± 0.793
5.479AspArg: 5.479 ± 1.784
2.74AspSer: 2.74 ± 0.783
5.479AspThr: 5.479 ± 0.9
3.425AspVal: 3.425 ± 1.761
1.37AspTrp: 1.37 ± 0.704
2.055AspTyr: 2.055 ± 0.768
0.0AspXaa: 0.0 ± 0.0
Glu
4.11GluAla: 4.11 ± 1.299
0.0GluCys: 0.0 ± 0.0
2.055GluAsp: 2.055 ± 1.056
2.055GluGlu: 2.055 ± 0.65
0.685GluPhe: 0.685 ± 1.135
7.534GluGly: 7.534 ± 2.777
0.685GluHis: 0.685 ± 0.352
3.425GluIle: 3.425 ± 0.94
2.055GluLys: 2.055 ± 1.056
6.849GluLeu: 6.849 ± 3.521
0.685GluMet: 0.685 ± 0.352
0.0GluAsn: 0.0 ± 0.0
0.685GluPro: 0.685 ± 0.352
5.479GluGln: 5.479 ± 1.784
2.055GluArg: 2.055 ± 1.056
4.11GluSer: 4.11 ± 2.647
2.74GluThr: 2.74 ± 1.408
3.425GluVal: 3.425 ± 0.625
1.37GluTrp: 1.37 ± 0.793
1.37GluTyr: 1.37 ± 0.704
0.0GluXaa: 0.0 ± 0.0
Phe
1.37PheAla: 1.37 ± 0.704
0.0PheCys: 0.0 ± 0.0
3.425PheAsp: 3.425 ± 0.867
1.37PheGlu: 1.37 ± 0.793
0.685PhePhe: 0.685 ± 0.352
0.685PheGly: 0.685 ± 0.352
0.0PheHis: 0.0 ± 0.0
0.685PheIle: 0.685 ± 1.135
2.74PheLys: 2.74 ± 0.68
4.11PheLeu: 4.11 ± 1.135
0.685PheMet: 0.685 ± 0.352
2.055PheAsn: 2.055 ± 0.768
1.37PhePro: 1.37 ± 0.704
2.055PheGln: 2.055 ± 0.768
0.685PheArg: 0.685 ± 1.041
3.425PheSer: 3.425 ± 1.761
2.055PheThr: 2.055 ± 2.547
2.74PheVal: 2.74 ± 2.204
0.0PheTrp: 0.0 ± 0.0
2.055PheTyr: 2.055 ± 1.817
0.0PheXaa: 0.0 ± 0.0
Gly
4.11GlyAla: 4.11 ± 1.135
0.685GlyCys: 0.685 ± 1.135
4.795GlyAsp: 4.795 ± 1.204
2.055GlyGlu: 2.055 ± 1.056
1.37GlyPhe: 1.37 ± 0.793
2.74GlyGly: 2.74 ± 1.408
0.0GlyHis: 0.0 ± 0.0
3.425GlyIle: 3.425 ± 2.013
4.795GlyLys: 4.795 ± 1.411
5.479GlyLeu: 5.479 ± 0.9
1.37GlyMet: 1.37 ± 0.704
0.685GlyAsn: 0.685 ± 1.135
2.74GlyPro: 2.74 ± 0.973
2.74GlyGln: 2.74 ± 1.806
2.74GlyArg: 2.74 ± 0.783
1.37GlySer: 1.37 ± 0.704
8.219GlyThr: 8.219 ± 1.854
4.795GlyVal: 4.795 ± 0.147
1.37GlyTrp: 1.37 ± 0.793
2.055GlyTyr: 2.055 ± 0.65
0.0GlyXaa: 0.0 ± 0.0
His
1.37HisAla: 1.37 ± 0.704
0.0HisCys: 0.0 ± 0.0
0.685HisAsp: 0.685 ± 0.352
1.37HisGlu: 1.37 ± 0.793
0.685HisPhe: 0.685 ± 0.352
1.37HisGly: 1.37 ± 0.704
0.685HisHis: 0.685 ± 1.041
0.685HisIle: 0.685 ± 0.352
0.685HisLys: 0.685 ± 0.352
0.685HisLeu: 0.685 ± 1.041
0.0HisMet: 0.0 ± 0.0
1.37HisAsn: 1.37 ± 0.704
2.74HisPro: 2.74 ± 0.783
1.37HisGln: 1.37 ± 0.704
0.0HisArg: 0.0 ± 0.0
1.37HisSer: 1.37 ± 0.704
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.685HisTyr: 0.685 ± 1.135
0.0HisXaa: 0.0 ± 0.0
Ile
4.795IleAla: 4.795 ± 0.147
0.0IleCys: 0.0 ± 0.0
3.425IleAsp: 3.425 ± 0.94
1.37IleGlu: 1.37 ± 0.704
1.37IlePhe: 1.37 ± 0.704
1.37IleGly: 1.37 ± 0.793
1.37IleHis: 1.37 ± 0.903
2.74IleIle: 2.74 ± 1.408
2.74IleLys: 2.74 ± 0.973
4.795IleLeu: 4.795 ± 2.297
2.055IleMet: 2.055 ± 1.056
2.74IleAsn: 2.74 ± 0.68
4.11IlePro: 4.11 ± 1.529
3.425IleGln: 3.425 ± 0.625
3.425IleArg: 3.425 ± 0.625
4.11IleSer: 4.11 ± 3.833
2.74IleThr: 2.74 ± 0.973
1.37IleVal: 1.37 ± 0.704
0.0IleTrp: 0.0 ± 0.0
2.74IleTyr: 2.74 ± 0.783
0.0IleXaa: 0.0 ± 0.0
Lys
6.164LysAla: 6.164 ± 0.647
0.685LysCys: 0.685 ± 0.352
4.795LysAsp: 4.795 ± 1.472
0.685LysGlu: 0.685 ± 0.352
4.11LysPhe: 4.11 ± 1.529
2.055LysGly: 2.055 ± 0.65
2.055LysHis: 2.055 ± 1.056
3.425LysIle: 3.425 ± 0.625
7.534LysLys: 7.534 ± 0.92
6.849LysLeu: 6.849 ± 1.152
0.685LysMet: 0.685 ± 1.135
2.74LysAsn: 2.74 ± 0.783
5.479LysPro: 5.479 ± 0.457
4.11LysGln: 4.11 ± 1.184
3.425LysArg: 3.425 ± 0.625
6.849LysSer: 6.849 ± 2.437
6.849LysThr: 6.849 ± 0.872
2.74LysVal: 2.74 ± 1.408
0.0LysTrp: 0.0 ± 0.0
1.37LysTyr: 1.37 ± 0.903
0.0LysXaa: 0.0 ± 0.0
Leu
8.219LeuAla: 8.219 ± 3.118
0.0LeuCys: 0.0 ± 0.0
4.795LeuAsp: 4.795 ± 3.393
6.164LeuGlu: 6.164 ± 0.803
6.164LeuPhe: 6.164 ± 2.094
6.164LeuGly: 6.164 ± 1.598
4.11LeuHis: 4.11 ± 1.299
2.055LeuIle: 2.055 ± 0.65
2.74LeuLys: 2.74 ± 0.973
8.904LeuLeu: 8.904 ± 1.407
2.74LeuMet: 2.74 ± 0.783
4.11LeuAsn: 4.11 ± 1.529
7.534LeuPro: 7.534 ± 0.907
4.795LeuGln: 4.795 ± 1.44
3.425LeuArg: 3.425 ± 0.867
6.849LeuSer: 6.849 ± 1.25
8.904LeuThr: 8.904 ± 0.289
4.11LeuVal: 4.11 ± 1.184
1.37LeuTrp: 1.37 ± 0.704
2.055LeuTyr: 2.055 ± 0.65
0.0LeuXaa: 0.0 ± 0.0
Met
2.74MetAla: 2.74 ± 1.408
1.37MetCys: 1.37 ± 0.704
2.055MetAsp: 2.055 ± 1.056
0.685MetGlu: 0.685 ± 1.041
0.685MetPhe: 0.685 ± 0.352
0.685MetGly: 0.685 ± 1.135
0.0MetHis: 0.0 ± 0.0
0.685MetIle: 0.685 ± 0.352
0.685MetLys: 0.685 ± 0.352
5.479MetLeu: 5.479 ± 1.784
0.0MetMet: 0.0 ± 0.0
0.685MetAsn: 0.685 ± 1.135
1.37MetPro: 1.37 ± 0.903
1.37MetGln: 1.37 ± 0.793
0.685MetArg: 0.685 ± 0.352
2.74MetSer: 2.74 ± 0.783
0.685MetThr: 0.685 ± 1.041
3.425MetVal: 3.425 ± 1.761
0.0MetTrp: 0.0 ± 0.0
0.685MetTyr: 0.685 ± 0.352
0.0MetXaa: 0.0 ± 0.0
Asn
2.055AsnAla: 2.055 ± 1.817
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
1.37AsnGlu: 1.37 ± 0.704
2.74AsnPhe: 2.74 ± 2.854
0.685AsnGly: 0.685 ± 0.352
0.0AsnHis: 0.0 ± 0.0
4.795AsnIle: 4.795 ± 2.297
4.795AsnLys: 4.795 ± 3.817
6.164AsnLeu: 6.164 ± 3.27
1.37AsnMet: 1.37 ± 0.903
2.055AsnAsn: 2.055 ± 2.021
1.37AsnPro: 1.37 ± 0.903
0.685AsnGln: 0.685 ± 0.352
2.74AsnArg: 2.74 ± 1.408
1.37AsnSer: 1.37 ± 0.704
2.74AsnThr: 2.74 ± 2.204
0.685AsnVal: 0.685 ± 0.352
0.685AsnTrp: 0.685 ± 0.352
0.685AsnTyr: 0.685 ± 0.352
0.0AsnXaa: 0.0 ± 0.0
Pro
2.74ProAla: 2.74 ± 1.586
0.0ProCys: 0.0 ± 0.0
4.795ProAsp: 4.795 ± 0.147
4.11ProGlu: 4.11 ± 2.113
0.685ProPhe: 0.685 ± 1.135
2.055ProGly: 2.055 ± 1.056
1.37ProHis: 1.37 ± 0.903
6.164ProIle: 6.164 ± 0.647
2.055ProLys: 2.055 ± 2.021
2.74ProLeu: 2.74 ± 1.408
2.74ProMet: 2.74 ± 1.523
2.055ProAsn: 2.055 ± 0.768
1.37ProPro: 1.37 ± 0.793
2.055ProGln: 2.055 ± 2.547
4.11ProArg: 4.11 ± 1.184
2.055ProSer: 2.055 ± 1.056
6.164ProThr: 6.164 ± 2.094
5.479ProVal: 5.479 ± 0.9
2.74ProTrp: 2.74 ± 2.204
2.74ProTyr: 2.74 ± 0.68
0.0ProXaa: 0.0 ± 0.0
Gln
4.11GlnAla: 4.11 ± 1.529
0.0GlnCys: 0.0 ± 0.0
2.74GlnAsp: 2.74 ± 0.68
1.37GlnGlu: 1.37 ± 0.704
0.685GlnPhe: 0.685 ± 0.352
2.74GlnGly: 2.74 ± 0.783
0.685GlnHis: 0.685 ± 0.352
2.74GlnIle: 2.74 ± 0.783
6.164GlnLys: 6.164 ± 1.693
3.425GlnLeu: 3.425 ± 0.867
0.685GlnMet: 0.685 ± 0.352
0.0GlnAsn: 0.0 ± 0.0
6.164GlnPro: 6.164 ± 0.647
5.479GlnGln: 5.479 ± 1.36
2.055GlnArg: 2.055 ± 1.056
2.74GlnSer: 2.74 ± 1.408
1.37GlnThr: 1.37 ± 0.793
4.795GlnVal: 4.795 ± 1.44
0.0GlnTrp: 0.0 ± 0.0
2.055GlnTyr: 2.055 ± 2.547
0.0GlnXaa: 0.0 ± 0.0
Arg
4.11ArgAla: 4.11 ± 1.135
0.685ArgCys: 0.685 ± 1.041
3.425ArgAsp: 3.425 ± 1.761
4.795ArgGlu: 4.795 ± 1.51
1.37ArgPhe: 1.37 ± 0.903
4.11ArgGly: 4.11 ± 1.184
0.685ArgHis: 0.685 ± 0.352
2.74ArgIle: 2.74 ± 0.973
3.425ArgLys: 3.425 ± 2.013
3.425ArgLeu: 3.425 ± 0.625
0.685ArgMet: 0.685 ± 1.041
4.11ArgAsn: 4.11 ± 1.135
1.37ArgPro: 1.37 ± 0.704
1.37ArgGln: 1.37 ± 0.704
0.685ArgArg: 0.685 ± 0.352
2.055ArgSer: 2.055 ± 0.65
2.74ArgThr: 2.74 ± 0.68
5.479ArgVal: 5.479 ± 1.784
1.37ArgTrp: 1.37 ± 0.704
2.74ArgTyr: 2.74 ± 0.783
0.0ArgXaa: 0.0 ± 0.0
Ser
5.479SerAla: 5.479 ± 2.545
0.685SerCys: 0.685 ± 0.352
2.055SerAsp: 2.055 ± 0.65
2.055SerGlu: 2.055 ± 1.056
2.055SerPhe: 2.055 ± 1.056
6.164SerGly: 6.164 ± 5.087
0.685SerHis: 0.685 ± 0.352
2.055SerIle: 2.055 ± 0.65
4.795SerLys: 4.795 ± 1.283
7.534SerLeu: 7.534 ± 0.907
2.055SerMet: 2.055 ± 1.056
2.74SerAsn: 2.74 ± 0.68
2.74SerPro: 2.74 ± 0.973
2.055SerGln: 2.055 ± 1.056
4.11SerArg: 4.11 ± 1.529
5.479SerSer: 5.479 ± 0.457
3.425SerThr: 3.425 ± 0.867
7.534SerVal: 7.534 ± 2.299
0.0SerTrp: 0.0 ± 0.0
2.74SerTyr: 2.74 ± 3.151
0.0SerXaa: 0.0 ± 0.0
Thr
6.849ThrAla: 6.849 ± 1.25
1.37ThrCys: 1.37 ± 0.903
3.425ThrAsp: 3.425 ± 1.761
4.11ThrGlu: 4.11 ± 2.113
1.37ThrPhe: 1.37 ± 1.675
3.425ThrGly: 3.425 ± 1.864
1.37ThrHis: 1.37 ± 0.704
4.11ThrIle: 4.11 ± 0.287
4.795ThrLys: 4.795 ± 1.44
10.274ThrLeu: 10.274 ± 3.031
2.055ThrMet: 2.055 ± 1.056
2.055ThrAsn: 2.055 ± 1.817
3.425ThrPro: 3.425 ± 0.625
4.11ThrGln: 4.11 ± 1.299
8.219ThrArg: 8.219 ± 0.855
4.795ThrSer: 4.795 ± 0.147
5.479ThrThr: 5.479 ± 1.36
3.425ThrVal: 3.425 ± 1.639
1.37ThrTrp: 1.37 ± 0.704
0.685ThrTyr: 0.685 ± 0.352
0.0ThrXaa: 0.0 ± 0.0
Val
5.479ValAla: 5.479 ± 1.565
2.055ValCys: 2.055 ± 1.817
6.164ValAsp: 6.164 ± 1.941
6.164ValGlu: 6.164 ± 2.108
1.37ValPhe: 1.37 ± 0.704
4.11ValGly: 4.11 ± 2.113
0.0ValHis: 0.0 ± 0.0
0.685ValIle: 0.685 ± 1.041
4.11ValLys: 4.11 ± 2.113
4.795ValLeu: 4.795 ± 1.472
2.055ValMet: 2.055 ± 0.65
2.055ValAsn: 2.055 ± 2.021
6.164ValPro: 6.164 ± 0.803
1.37ValGln: 1.37 ± 0.704
2.74ValArg: 2.74 ± 0.783
4.795ValSer: 4.795 ± 1.51
6.164ValThr: 6.164 ± 2.285
5.479ValVal: 5.479 ± 1.36
0.685ValTrp: 0.685 ± 0.352
2.055ValTyr: 2.055 ± 1.056
0.0ValXaa: 0.0 ± 0.0
Trp
0.685TrpAla: 0.685 ± 0.352
0.0TrpCys: 0.0 ± 0.0
1.37TrpAsp: 1.37 ± 0.704
1.37TrpGlu: 1.37 ± 0.793
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.685TrpHis: 0.685 ± 0.352
0.685TrpIle: 0.685 ± 0.352
1.37TrpLys: 1.37 ± 0.704
0.685TrpLeu: 0.685 ± 0.352
2.055TrpMet: 2.055 ± 0.976
1.37TrpAsn: 1.37 ± 2.083
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.685TrpArg: 0.685 ± 0.352
0.685TrpSer: 0.685 ± 0.352
1.37TrpThr: 1.37 ± 0.793
2.055TrpVal: 2.055 ± 0.768
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.425TyrAla: 3.425 ± 0.94
0.685TyrCys: 0.685 ± 0.352
0.685TyrAsp: 0.685 ± 0.352
2.74TyrGlu: 2.74 ± 0.783
0.685TyrPhe: 0.685 ± 1.041
2.74TyrGly: 2.74 ± 0.973
0.0TyrHis: 0.0 ± 0.0
0.685TyrIle: 0.685 ± 0.352
1.37TyrLys: 1.37 ± 0.704
2.055TyrLeu: 2.055 ± 0.65
0.0TyrMet: 0.0 ± 0.0
0.685TyrAsn: 0.685 ± 1.135
2.055TyrPro: 2.055 ± 0.65
1.37TyrGln: 1.37 ± 0.793
1.37TyrArg: 1.37 ± 2.27
2.74TyrSer: 2.74 ± 2.335
5.479TyrThr: 5.479 ± 0.457
1.37TyrVal: 1.37 ± 0.704
1.37TyrTrp: 1.37 ± 0.704
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1461 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski