Amino acid dipepetide frequency for Spiroplasma virus SpV1-R8A2 B (SpV1) (Spiroplasma virus 1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.46AlaAla: 0.46 ± 0.471
0.0AlaCys: 0.0 ± 0.0
0.46AlaAsp: 0.46 ± 0.319
0.92AlaGlu: 0.92 ± 0.555
2.299AlaPhe: 2.299 ± 1.001
0.46AlaGly: 0.46 ± 0.508
0.46AlaHis: 0.46 ± 0.319
5.057AlaIle: 5.057 ± 1.779
2.299AlaLys: 2.299 ± 1.27
2.759AlaLeu: 2.759 ± 0.937
0.0AlaMet: 0.0 ± 0.0
1.839AlaAsn: 1.839 ± 0.674
0.0AlaPro: 0.0 ± 0.0
0.92AlaGln: 0.92 ± 0.483
0.92AlaArg: 0.92 ± 0.555
2.299AlaSer: 2.299 ± 0.832
0.0AlaThr: 0.0 ± 0.0
1.379AlaVal: 1.379 ± 0.708
0.46AlaTrp: 0.46 ± 0.614
0.92AlaTyr: 0.92 ± 0.689
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.46CysAsp: 0.46 ± 0.508
0.0CysGlu: 0.0 ± 0.0
1.379CysPhe: 1.379 ± 1.429
0.46CysGly: 0.46 ± 0.616
0.0CysHis: 0.0 ± 0.0
1.379CysIle: 1.379 ± 0.917
0.0CysLys: 0.0 ± 0.0
0.46CysLeu: 0.46 ± 0.508
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.92CysVal: 0.92 ± 0.555
0.0CysTrp: 0.0 ± 0.0
1.379CysTyr: 1.379 ± 1.002
0.0CysXaa: 0.0 ± 0.0
Asp
0.46AspAla: 0.46 ± 0.508
0.0AspCys: 0.0 ± 0.0
1.839AspAsp: 1.839 ± 1.343
3.678AspGlu: 3.678 ± 1.542
5.057AspPhe: 5.057 ± 1.669
1.839AspGly: 1.839 ± 0.754
0.46AspHis: 0.46 ± 0.508
3.218AspIle: 3.218 ± 1.248
6.897AspLys: 6.897 ± 1.545
5.977AspLeu: 5.977 ± 1.764
1.839AspMet: 1.839 ± 0.681
4.138AspAsn: 4.138 ± 0.879
0.0AspPro: 0.0 ± 0.0
0.0AspGln: 0.0 ± 0.0
1.379AspArg: 1.379 ± 0.438
1.839AspSer: 1.839 ± 0.769
1.839AspThr: 1.839 ± 0.745
2.299AspVal: 2.299 ± 0.966
1.379AspTrp: 1.379 ± 0.787
1.379AspTyr: 1.379 ± 0.672
0.0AspXaa: 0.0 ± 0.0
Glu
0.92GluAla: 0.92 ± 0.618
0.46GluCys: 0.46 ± 0.616
0.46GluAsp: 0.46 ± 0.467
1.839GluGlu: 1.839 ± 0.656
2.759GluPhe: 2.759 ± 1.27
2.299GluGly: 2.299 ± 1.535
0.46GluHis: 0.46 ± 0.558
7.356GluIle: 7.356 ± 1.391
3.678GluLys: 3.678 ± 1.689
4.598GluLeu: 4.598 ± 0.997
1.839GluMet: 1.839 ± 1.585
6.437GluAsn: 6.437 ± 2.704
0.92GluPro: 0.92 ± 0.529
3.678GluGln: 3.678 ± 1.835
2.299GluArg: 2.299 ± 1.252
2.299GluSer: 2.299 ± 0.878
2.299GluThr: 2.299 ± 1.168
1.839GluVal: 1.839 ± 0.656
0.46GluTrp: 0.46 ± 0.319
2.299GluTyr: 2.299 ± 1.3
0.0GluXaa: 0.0 ± 0.0
Phe
4.138PheAla: 4.138 ± 0.853
1.839PheCys: 1.839 ± 1.181
5.057PheAsp: 5.057 ± 1.778
2.759PheGlu: 2.759 ± 1.489
6.437PhePhe: 6.437 ± 2.147
4.138PheGly: 4.138 ± 1.412
0.0PheHis: 0.0 ± 0.0
10.575PheIle: 10.575 ± 2.495
9.195PheLys: 9.195 ± 2.04
11.494PheLeu: 11.494 ± 3.189
2.299PheMet: 2.299 ± 0.789
6.437PheAsn: 6.437 ± 1.815
1.839PhePro: 1.839 ± 1.0
0.92PheGln: 0.92 ± 0.483
0.92PheArg: 0.92 ± 0.618
5.517PheSer: 5.517 ± 0.985
2.759PheThr: 2.759 ± 1.369
4.598PheVal: 4.598 ± 1.943
1.379PheTrp: 1.379 ± 0.951
3.678PheTyr: 3.678 ± 1.109
0.0PheXaa: 0.0 ± 0.0
Gly
0.46GlyAla: 0.46 ± 0.319
0.0GlyCys: 0.0 ± 0.0
0.92GlyAsp: 0.92 ± 0.639
2.759GlyGlu: 2.759 ± 1.145
4.138GlyPhe: 4.138 ± 1.497
1.379GlyGly: 1.379 ± 0.958
0.0GlyHis: 0.0 ± 0.0
4.138GlyIle: 4.138 ± 1.347
6.437GlyLys: 6.437 ± 2.5
5.517GlyLeu: 5.517 ± 1.537
2.299GlyMet: 2.299 ± 1.207
1.379GlyAsn: 1.379 ± 1.033
0.0GlyPro: 0.0 ± 0.0
0.46GlyGln: 0.46 ± 0.319
0.46GlyArg: 0.46 ± 0.471
3.218GlySer: 3.218 ± 1.009
3.218GlyThr: 3.218 ± 0.925
3.678GlyVal: 3.678 ± 1.303
0.92GlyTrp: 0.92 ± 0.478
2.759GlyTyr: 2.759 ± 1.278
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
1.379HisAsp: 1.379 ± 0.717
0.0HisGlu: 0.0 ± 0.0
0.46HisPhe: 0.46 ± 0.467
0.92HisGly: 0.92 ± 0.689
0.46HisHis: 0.46 ± 0.508
2.299HisIle: 2.299 ± 1.37
1.379HisLys: 1.379 ± 0.697
0.92HisLeu: 0.92 ± 1.016
0.0HisMet: 0.0 ± 0.0
1.379HisAsn: 1.379 ± 1.046
0.46HisPro: 0.46 ± 0.471
0.0HisGln: 0.0 ± 0.0
0.46HisArg: 0.46 ± 0.508
1.379HisSer: 1.379 ± 0.614
0.46HisThr: 0.46 ± 0.508
0.0HisVal: 0.0 ± 0.0
0.46HisTrp: 0.46 ± 0.508
0.46HisTyr: 0.46 ± 0.319
0.0HisXaa: 0.0 ± 0.0
Ile
1.379IleAla: 1.379 ± 0.84
0.0IleCys: 0.0 ± 0.0
5.057IleAsp: 5.057 ± 1.33
4.138IleGlu: 4.138 ± 1.383
10.115IlePhe: 10.115 ± 1.987
3.218IleGly: 3.218 ± 1.209
1.379IleHis: 1.379 ± 0.844
12.414IleIle: 12.414 ± 4.215
8.276IleLys: 8.276 ± 1.797
7.356IleLeu: 7.356 ± 2.414
3.678IleMet: 3.678 ± 1.227
7.356IleAsn: 7.356 ± 2.025
3.218IlePro: 3.218 ± 1.348
0.0IleGln: 0.0 ± 0.0
3.218IleArg: 3.218 ± 1.454
6.437IleSer: 6.437 ± 1.999
5.057IleThr: 5.057 ± 1.055
5.517IleVal: 5.517 ± 1.796
4.598IleTrp: 4.598 ± 0.938
6.897IleTyr: 6.897 ± 1.151
0.0IleXaa: 0.0 ± 0.0
Lys
1.839LysAla: 1.839 ± 1.595
0.46LysCys: 0.46 ± 0.616
3.218LysAsp: 3.218 ± 0.874
8.276LysGlu: 8.276 ± 1.356
6.897LysPhe: 6.897 ± 1.307
4.138LysGly: 4.138 ± 1.075
1.839LysHis: 1.839 ± 0.792
9.195LysIle: 9.195 ± 1.897
12.414LysLys: 12.414 ± 3.108
8.276LysLeu: 8.276 ± 1.607
2.759LysMet: 2.759 ± 1.21
9.195LysAsn: 9.195 ± 1.804
2.759LysPro: 2.759 ± 1.249
7.356LysGln: 7.356 ± 2.399
4.138LysArg: 4.138 ± 2.018
3.218LysSer: 3.218 ± 1.75
4.138LysThr: 4.138 ± 1.255
5.977LysVal: 5.977 ± 1.607
1.839LysTrp: 1.839 ± 1.03
5.977LysTyr: 5.977 ± 1.616
0.0LysXaa: 0.0 ± 0.0
Leu
2.299LeuAla: 2.299 ± 1.091
0.46LeuCys: 0.46 ± 0.616
1.839LeuAsp: 1.839 ± 0.935
4.598LeuGlu: 4.598 ± 1.405
9.655LeuPhe: 9.655 ± 2.945
3.218LeuGly: 3.218 ± 1.198
0.0LeuHis: 0.0 ± 0.0
9.195LeuIle: 9.195 ± 2.099
9.655LeuLys: 9.655 ± 1.414
10.575LeuLeu: 10.575 ± 2.726
0.92LeuMet: 0.92 ± 0.82
6.897LeuAsn: 6.897 ± 1.672
1.379LeuPro: 1.379 ± 1.08
5.057LeuGln: 5.057 ± 2.57
4.138LeuArg: 4.138 ± 2.45
7.356LeuSer: 7.356 ± 0.983
7.816LeuThr: 7.816 ± 2.419
6.437LeuVal: 6.437 ± 1.385
1.839LeuTrp: 1.839 ± 1.197
6.437LeuTyr: 6.437 ± 1.521
0.0LeuXaa: 0.0 ± 0.0
Met
0.46MetAla: 0.46 ± 0.471
0.46MetCys: 0.46 ± 0.558
1.839MetAsp: 1.839 ± 1.276
0.92MetGlu: 0.92 ± 0.737
1.839MetPhe: 1.839 ± 0.884
0.46MetGly: 0.46 ± 0.319
0.0MetHis: 0.0 ± 0.0
2.299MetIle: 2.299 ± 0.879
3.678MetLys: 3.678 ± 1.162
2.299MetLeu: 2.299 ± 1.327
0.0MetMet: 0.0 ± 0.0
0.46MetAsn: 0.46 ± 0.508
0.92MetPro: 0.92 ± 0.9
1.379MetGln: 1.379 ± 0.826
0.92MetArg: 0.92 ± 0.639
0.92MetSer: 0.92 ± 0.921
0.92MetThr: 0.92 ± 0.784
3.218MetVal: 3.218 ± 1.992
0.46MetTrp: 0.46 ± 0.632
1.839MetTyr: 1.839 ± 1.031
0.0MetXaa: 0.0 ± 0.0
Asn
0.92AsnAla: 0.92 ± 0.635
0.0AsnCys: 0.0 ± 0.0
4.138AsnAsp: 4.138 ± 1.085
2.299AsnGlu: 2.299 ± 1.048
6.897AsnPhe: 6.897 ± 1.622
3.218AsnGly: 3.218 ± 1.009
1.839AsnHis: 1.839 ± 1.06
6.437AsnIle: 6.437 ± 1.512
5.977AsnLys: 5.977 ± 1.056
8.736AsnLeu: 8.736 ± 2.689
1.379AsnMet: 1.379 ± 0.768
9.655AsnAsn: 9.655 ± 3.205
1.839AsnPro: 1.839 ± 0.935
1.379AsnGln: 1.379 ± 0.852
3.678AsnArg: 3.678 ± 0.834
4.598AsnSer: 4.598 ± 1.044
3.218AsnThr: 3.218 ± 1.524
3.218AsnVal: 3.218 ± 1.523
3.218AsnTrp: 3.218 ± 1.069
4.598AsnTyr: 4.598 ± 1.717
0.0AsnXaa: 0.0 ± 0.0
Pro
0.46ProAla: 0.46 ± 0.319
0.46ProCys: 0.46 ± 0.508
0.92ProAsp: 0.92 ± 0.483
0.46ProGlu: 0.46 ± 0.614
1.839ProPhe: 1.839 ± 1.045
0.92ProGly: 0.92 ± 0.639
0.46ProHis: 0.46 ± 0.467
0.92ProIle: 0.92 ± 0.709
2.299ProLys: 2.299 ± 0.76
3.218ProLeu: 3.218 ± 1.343
0.92ProMet: 0.92 ± 0.71
0.92ProAsn: 0.92 ± 0.529
0.46ProPro: 0.46 ± 0.467
0.92ProGln: 0.92 ± 0.478
0.92ProArg: 0.92 ± 0.639
0.92ProSer: 0.92 ± 0.727
1.379ProThr: 1.379 ± 0.754
1.839ProVal: 1.839 ± 0.769
0.46ProTrp: 0.46 ± 0.467
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
0.92GlnAla: 0.92 ± 0.559
0.46GlnCys: 0.46 ± 0.467
1.379GlnAsp: 1.379 ± 0.672
1.839GlnGlu: 1.839 ± 0.902
2.759GlnPhe: 2.759 ± 1.282
1.839GlnGly: 1.839 ± 1.117
0.0GlnHis: 0.0 ± 0.0
2.299GlnIle: 2.299 ± 0.81
3.678GlnLys: 3.678 ± 1.127
3.218GlnLeu: 3.218 ± 1.305
0.46GlnMet: 0.46 ± 0.616
4.138GlnAsn: 4.138 ± 1.837
0.0GlnPro: 0.0 ± 0.0
1.839GlnGln: 1.839 ± 0.884
0.46GlnArg: 0.46 ± 0.467
1.379GlnSer: 1.379 ± 0.958
0.92GlnThr: 0.92 ± 0.483
2.299GlnVal: 2.299 ± 0.759
1.379GlnTrp: 1.379 ± 0.672
2.759GlnTyr: 2.759 ± 1.228
0.0GlnXaa: 0.0 ± 0.0
Arg
0.46ArgAla: 0.46 ± 0.467
0.0ArgCys: 0.0 ± 0.0
0.92ArgAsp: 0.92 ± 0.704
2.299ArgGlu: 2.299 ± 1.455
3.218ArgPhe: 3.218 ± 1.325
1.839ArgGly: 1.839 ± 1.024
2.759ArgHis: 2.759 ± 1.72
0.46ArgIle: 0.46 ± 0.319
2.759ArgLys: 2.759 ± 1.725
1.839ArgLeu: 1.839 ± 0.679
0.92ArgMet: 0.92 ± 0.509
0.92ArgAsn: 0.92 ± 0.747
0.92ArgPro: 0.92 ± 0.478
1.379ArgGln: 1.379 ± 0.724
0.92ArgArg: 0.92 ± 0.689
1.379ArgSer: 1.379 ± 0.635
1.839ArgThr: 1.839 ± 0.965
3.218ArgVal: 3.218 ± 0.912
0.46ArgTrp: 0.46 ± 0.319
2.299ArgTyr: 2.299 ± 1.168
0.0ArgXaa: 0.0 ± 0.0
Ser
3.678SerAla: 3.678 ± 1.463
0.0SerCys: 0.0 ± 0.0
2.759SerAsp: 2.759 ± 0.935
4.138SerGlu: 4.138 ± 1.517
5.517SerPhe: 5.517 ± 1.245
3.218SerGly: 3.218 ± 1.597
0.92SerHis: 0.92 ± 0.694
3.218SerIle: 3.218 ± 1.341
5.517SerLys: 5.517 ± 1.821
5.977SerLeu: 5.977 ± 2.121
1.379SerMet: 1.379 ± 0.613
2.759SerAsn: 2.759 ± 1.419
1.379SerPro: 1.379 ± 0.957
2.759SerGln: 2.759 ± 0.785
0.46SerArg: 0.46 ± 0.319
4.598SerSer: 4.598 ± 1.327
3.678SerThr: 3.678 ± 1.576
4.598SerVal: 4.598 ± 1.809
0.0SerTrp: 0.0 ± 0.0
2.759SerTyr: 2.759 ± 1.106
0.0SerXaa: 0.0 ± 0.0
Thr
2.759ThrAla: 2.759 ± 1.188
0.0ThrCys: 0.0 ± 0.0
4.598ThrAsp: 4.598 ± 1.336
1.839ThrGlu: 1.839 ± 1.271
1.379ThrPhe: 1.379 ± 0.629
4.138ThrGly: 4.138 ± 1.457
0.0ThrHis: 0.0 ± 0.0
4.598ThrIle: 4.598 ± 1.47
3.678ThrLys: 3.678 ± 1.708
3.218ThrLeu: 3.218 ± 0.832
1.839ThrMet: 1.839 ± 0.906
3.218ThrAsn: 3.218 ± 1.227
1.379ThrPro: 1.379 ± 0.769
1.379ThrGln: 1.379 ± 0.963
0.46ThrArg: 0.46 ± 0.516
2.299ThrSer: 2.299 ± 1.116
1.839ThrThr: 1.839 ± 1.335
4.138ThrVal: 4.138 ± 1.305
1.379ThrTrp: 1.379 ± 1.04
0.92ThrTyr: 0.92 ± 0.483
0.0ThrXaa: 0.0 ± 0.0
Val
1.379ValAla: 1.379 ± 0.613
0.92ValCys: 0.92 ± 0.737
1.839ValAsp: 1.839 ± 0.918
4.598ValGlu: 4.598 ± 1.332
5.517ValPhe: 5.517 ± 1.636
4.598ValGly: 4.598 ± 1.486
0.92ValHis: 0.92 ± 0.667
6.897ValIle: 6.897 ± 1.439
8.276ValLys: 8.276 ± 1.522
5.057ValLeu: 5.057 ± 1.574
0.46ValMet: 0.46 ± 0.614
4.138ValAsn: 4.138 ± 1.07
0.92ValPro: 0.92 ± 0.483
1.839ValGln: 1.839 ± 1.032
1.379ValArg: 1.379 ± 0.635
2.759ValSer: 2.759 ± 1.342
0.92ValThr: 0.92 ± 0.534
1.839ValVal: 1.839 ± 1.088
2.299ValTrp: 2.299 ± 1.03
2.299ValTyr: 2.299 ± 0.984
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
2.299TrpAsp: 2.299 ± 0.586
0.46TrpGlu: 0.46 ± 0.319
0.92TrpPhe: 0.92 ± 0.866
0.0TrpGly: 0.0 ± 0.0
0.46TrpHis: 0.46 ± 0.319
4.598TrpIle: 4.598 ± 1.748
3.218TrpLys: 3.218 ± 1.066
4.138TrpLeu: 4.138 ± 1.432
0.46TrpMet: 0.46 ± 0.632
2.299TrpAsn: 2.299 ± 0.873
0.0TrpPro: 0.0 ± 0.0
0.92TrpGln: 0.92 ± 0.639
0.46TrpArg: 0.46 ± 0.508
1.379TrpSer: 1.379 ± 0.614
0.92TrpThr: 0.92 ± 0.871
0.46TrpVal: 0.46 ± 0.508
1.379TrpTrp: 1.379 ± 0.672
0.46TrpTyr: 0.46 ± 0.319
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.92TyrAla: 0.92 ± 0.559
0.92TyrCys: 0.92 ± 0.934
4.138TyrAsp: 4.138 ± 1.698
1.379TyrGlu: 1.379 ± 0.438
6.897TyrPhe: 6.897 ± 1.284
1.839TyrGly: 1.839 ± 0.884
0.46TyrHis: 0.46 ± 0.508
2.759TyrIle: 2.759 ± 0.985
5.057TyrLys: 5.057 ± 1.504
4.138TyrLeu: 4.138 ± 1.087
1.379TyrMet: 1.379 ± 0.689
3.678TyrAsn: 3.678 ± 1.44
2.299TyrPro: 2.299 ± 1.046
1.839TyrGln: 1.839 ± 0.811
3.218TyrArg: 3.218 ± 1.133
5.517TyrSer: 5.517 ± 1.716
1.839TyrThr: 1.839 ± 1.001
1.379TyrVal: 1.379 ± 0.958
0.46TyrTrp: 0.46 ± 0.467
2.759TyrTyr: 2.759 ± 1.033
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 12 proteins (2176 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski