Amino acid dipepetide frequency for Hubei zhaovirus-like virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.723AlaAla: 1.723 ± 2.269
1.723AlaCys: 1.723 ± 0.811
0.574AlaAsp: 0.574 ± 1.27
0.574AlaGlu: 0.574 ± 0.27
2.298AlaPhe: 2.298 ± 1.081
2.298AlaGly: 2.298 ± 1.999
0.0AlaHis: 0.0 ± 0.0
2.298AlaIle: 2.298 ± 1.081
2.298AlaLys: 2.298 ± 1.081
4.595AlaLeu: 4.595 ± 0.918
1.723AlaMet: 1.723 ± 0.22
1.149AlaAsn: 1.149 ± 1.0
1.149AlaPro: 1.149 ± 1.0
4.021AlaGln: 4.021 ± 5.808
1.723AlaArg: 1.723 ± 0.811
5.169AlaSer: 5.169 ± 0.648
1.723AlaThr: 1.723 ± 0.729
5.169AlaVal: 5.169 ± 0.648
1.723AlaTrp: 1.723 ± 0.811
4.021AlaTyr: 4.021 ± 0.352
0.0AlaXaa: 0.0 ± 0.0
Cys
0.574CysAla: 0.574 ± 0.27
1.149CysCys: 1.149 ± 0.54
1.149CysAsp: 1.149 ± 0.54
0.574CysGlu: 0.574 ± 0.27
0.574CysPhe: 0.574 ± 0.27
1.723CysGly: 1.723 ± 0.811
1.149CysHis: 1.149 ± 0.54
1.149CysIle: 1.149 ± 0.54
1.723CysLys: 1.723 ± 0.811
0.574CysLeu: 0.574 ± 0.27
0.0CysMet: 0.0 ± 0.0
1.149CysAsn: 1.149 ± 0.54
1.723CysPro: 1.723 ± 2.269
1.723CysGln: 1.723 ± 0.811
0.574CysArg: 0.574 ± 0.27
1.149CysSer: 1.149 ± 0.54
0.574CysThr: 0.574 ± 0.27
0.574CysVal: 0.574 ± 0.27
0.0CysTrp: 0.0 ± 0.0
0.574CysTyr: 0.574 ± 1.27
0.0CysXaa: 0.0 ± 0.0
Asp
0.574AspAla: 0.574 ± 0.27
0.574AspCys: 0.574 ± 0.27
2.872AspAsp: 2.872 ± 1.351
2.872AspGlu: 2.872 ± 1.351
3.446AspPhe: 3.446 ± 1.621
2.298AspGly: 2.298 ± 0.459
2.298AspHis: 2.298 ± 1.081
6.893AspIle: 6.893 ± 0.163
6.893AspLys: 6.893 ± 1.703
3.446AspLeu: 3.446 ± 0.081
0.574AspMet: 0.574 ± 0.27
5.169AspAsn: 5.169 ± 0.892
1.723AspPro: 1.723 ± 0.729
2.298AspGln: 2.298 ± 0.459
1.723AspArg: 1.723 ± 0.811
4.595AspSer: 4.595 ± 0.622
2.298AspThr: 2.298 ± 1.999
4.021AspVal: 4.021 ± 0.352
0.0AspTrp: 0.0 ± 0.0
3.446AspTyr: 3.446 ± 0.081
0.0AspXaa: 0.0 ± 0.0
Glu
2.298GluAla: 2.298 ± 0.459
0.574GluCys: 0.574 ± 0.27
1.723GluAsp: 1.723 ± 0.811
4.021GluGlu: 4.021 ± 1.892
1.723GluPhe: 1.723 ± 2.269
1.723GluGly: 1.723 ± 0.811
2.298GluHis: 2.298 ± 1.081
1.149GluIle: 1.149 ± 0.54
5.169GluLys: 5.169 ± 0.892
2.872GluLeu: 2.872 ± 1.729
0.0GluMet: 0.0 ± 0.0
1.723GluAsn: 1.723 ± 0.811
0.574GluPro: 0.574 ± 0.27
4.021GluGln: 4.021 ± 1.892
1.723GluArg: 1.723 ± 0.811
2.298GluSer: 2.298 ± 0.459
2.298GluThr: 2.298 ± 1.081
0.574GluVal: 0.574 ± 0.27
1.149GluTrp: 1.149 ± 0.54
1.149GluTyr: 1.149 ± 1.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.298PheAla: 2.298 ± 0.459
1.723PheCys: 1.723 ± 0.729
4.021PheAsp: 4.021 ± 0.352
1.723PheGlu: 1.723 ± 0.729
4.021PhePhe: 4.021 ± 0.352
3.446PheGly: 3.446 ± 1.621
0.574PheHis: 0.574 ± 0.27
1.149PheIle: 1.149 ± 0.54
2.298PheLys: 2.298 ± 1.081
4.021PheLeu: 4.021 ± 0.352
0.574PheMet: 0.574 ± 0.27
5.744PheAsn: 5.744 ± 2.702
3.446PhePro: 3.446 ± 0.081
3.446PheGln: 3.446 ± 1.621
1.723PheArg: 1.723 ± 0.729
2.298PheSer: 2.298 ± 0.459
1.723PheThr: 1.723 ± 2.269
5.744PheVal: 5.744 ± 1.162
0.0PheTrp: 0.0 ± 0.0
2.298PheTyr: 2.298 ± 1.081
0.0PheXaa: 0.0 ± 0.0
Gly
2.872GlyAla: 2.872 ± 0.189
0.574GlyCys: 0.574 ± 0.27
2.298GlyAsp: 2.298 ± 1.081
2.298GlyGlu: 2.298 ± 0.459
3.446GlyPhe: 3.446 ± 1.459
1.149GlyGly: 1.149 ± 0.54
2.872GlyHis: 2.872 ± 1.351
1.149GlyIle: 1.149 ± 1.0
1.723GlyLys: 1.723 ± 0.811
5.169GlyLeu: 5.169 ± 0.892
0.574GlyMet: 0.574 ± 0.453
4.021GlyAsn: 4.021 ± 4.268
1.723GlyPro: 1.723 ± 0.811
2.872GlyGln: 2.872 ± 1.351
0.574GlyArg: 0.574 ± 1.27
3.446GlySer: 3.446 ± 0.081
3.446GlyThr: 3.446 ± 2.999
4.595GlyVal: 4.595 ± 0.622
0.574GlyTrp: 0.574 ± 0.27
3.446GlyTyr: 3.446 ± 1.621
0.0GlyXaa: 0.0 ± 0.0
His
1.723HisAla: 1.723 ± 0.811
0.0HisCys: 0.0 ± 0.0
1.149HisAsp: 1.149 ± 0.54
1.149HisGlu: 1.149 ± 0.54
0.574HisPhe: 0.574 ± 0.27
1.149HisGly: 1.149 ± 0.54
0.0HisHis: 0.0 ± 0.0
0.574HisIle: 0.574 ± 1.27
1.149HisLys: 1.149 ± 0.54
0.0HisLeu: 0.0 ± 0.0
0.574HisMet: 0.574 ± 0.27
1.723HisAsn: 1.723 ± 0.729
0.574HisPro: 0.574 ± 0.27
1.149HisGln: 1.149 ± 0.54
1.149HisArg: 1.149 ± 0.54
1.723HisSer: 1.723 ± 0.811
2.872HisThr: 2.872 ± 1.351
0.574HisVal: 0.574 ± 0.27
0.574HisTrp: 0.574 ± 0.27
1.149HisTyr: 1.149 ± 0.54
0.0HisXaa: 0.0 ± 0.0
Ile
3.446IleAla: 3.446 ± 1.621
0.0IleCys: 0.0 ± 0.0
5.169IleAsp: 5.169 ± 2.432
4.595IleGlu: 4.595 ± 0.622
3.446IlePhe: 3.446 ± 0.081
4.595IleGly: 4.595 ± 0.622
1.723IleHis: 1.723 ± 0.729
3.446IleIle: 3.446 ± 0.081
3.446IleLys: 3.446 ± 1.621
4.021IleLeu: 4.021 ± 1.892
2.298IleMet: 2.298 ± 0.459
2.298IleAsn: 2.298 ± 0.459
1.723IlePro: 1.723 ± 0.811
6.318IleGln: 6.318 ± 0.107
1.149IleArg: 1.149 ± 0.54
1.723IleSer: 1.723 ± 0.811
4.021IleThr: 4.021 ± 2.728
5.169IleVal: 5.169 ± 0.648
1.723IleTrp: 1.723 ± 0.811
4.021IleTyr: 4.021 ± 1.188
0.0IleXaa: 0.0 ± 0.0
Lys
1.149LysAla: 1.149 ± 0.54
0.0LysCys: 0.0 ± 0.0
5.169LysAsp: 5.169 ± 2.432
4.595LysGlu: 4.595 ± 2.162
3.446LysPhe: 3.446 ± 1.459
4.021LysGly: 4.021 ± 1.892
1.149LysHis: 1.149 ± 0.54
5.744LysIle: 5.744 ± 1.162
4.595LysLys: 4.595 ± 2.162
4.021LysLeu: 4.021 ± 1.188
2.298LysMet: 2.298 ± 0.459
5.169LysAsn: 5.169 ± 0.648
2.298LysPro: 2.298 ± 1.081
5.169LysGln: 5.169 ± 0.648
5.169LysArg: 5.169 ± 2.432
6.318LysSer: 6.318 ± 0.107
6.893LysThr: 6.893 ± 1.703
4.021LysVal: 4.021 ± 0.352
0.574LysTrp: 0.574 ± 0.27
4.595LysTyr: 4.595 ± 0.918
0.0LysXaa: 0.0 ± 0.0
Leu
3.446LeuAla: 3.446 ± 2.999
0.574LeuCys: 0.574 ± 0.27
4.021LeuAsp: 4.021 ± 0.352
0.574LeuGlu: 0.574 ± 0.27
3.446LeuPhe: 3.446 ± 1.621
2.298LeuGly: 2.298 ± 0.459
1.149LeuHis: 1.149 ± 0.54
4.595LeuIle: 4.595 ± 2.162
9.765LeuLys: 9.765 ± 1.566
9.19LeuLeu: 9.19 ± 1.244
1.723LeuMet: 1.723 ± 0.729
5.169LeuAsn: 5.169 ± 0.892
2.298LeuPro: 2.298 ± 1.999
4.021LeuGln: 4.021 ± 0.352
4.021LeuArg: 4.021 ± 1.188
9.765LeuSer: 9.765 ± 1.514
5.169LeuThr: 5.169 ± 2.188
4.595LeuVal: 4.595 ± 2.162
0.574LeuTrp: 0.574 ± 0.27
6.893LeuTyr: 6.893 ± 1.703
0.0LeuXaa: 0.0 ± 0.0
Met
0.574MetAla: 0.574 ± 0.27
0.0MetCys: 0.0 ± 0.0
1.149MetAsp: 1.149 ± 0.54
0.574MetGlu: 0.574 ± 1.27
1.149MetPhe: 1.149 ± 0.54
1.149MetGly: 1.149 ± 1.0
0.574MetHis: 0.574 ± 0.27
1.723MetIle: 1.723 ± 0.811
2.872MetLys: 2.872 ± 1.729
2.872MetLeu: 2.872 ± 0.189
0.574MetMet: 0.574 ± 0.27
2.872MetAsn: 2.872 ± 1.729
0.574MetPro: 0.574 ± 1.27
0.0MetGln: 0.0 ± 0.0
1.149MetArg: 1.149 ± 1.0
2.872MetSer: 2.872 ± 1.351
3.446MetThr: 3.446 ± 1.459
0.574MetVal: 0.574 ± 0.27
0.0MetTrp: 0.0 ± 0.0
1.149MetTyr: 1.149 ± 1.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.149AsnAla: 1.149 ± 0.54
1.723AsnCys: 1.723 ± 0.811
2.298AsnAsp: 2.298 ± 1.081
1.723AsnGlu: 1.723 ± 0.811
1.723AsnPhe: 1.723 ± 0.729
2.298AsnGly: 2.298 ± 1.081
0.574AsnHis: 0.574 ± 0.27
7.467AsnIle: 7.467 ± 1.973
4.021AsnLys: 4.021 ± 1.892
5.744AsnLeu: 5.744 ± 1.918
0.574AsnMet: 0.574 ± 0.27
5.169AsnAsn: 5.169 ± 2.432
1.723AsnPro: 1.723 ± 2.269
4.595AsnGln: 4.595 ± 0.622
1.149AsnArg: 1.149 ± 1.0
5.169AsnSer: 5.169 ± 0.892
2.298AsnThr: 2.298 ± 0.459
4.595AsnVal: 4.595 ± 2.458
0.574AsnTrp: 0.574 ± 0.27
5.744AsnTyr: 5.744 ± 3.458
0.0AsnXaa: 0.0 ± 0.0
Pro
1.723ProAla: 1.723 ± 0.729
0.0ProCys: 0.0 ± 0.0
1.723ProAsp: 1.723 ± 0.729
0.574ProGlu: 0.574 ± 0.27
1.723ProPhe: 1.723 ± 0.729
2.298ProGly: 2.298 ± 1.999
0.0ProHis: 0.0 ± 0.0
1.149ProIle: 1.149 ± 0.54
4.021ProLys: 4.021 ± 1.188
2.298ProLeu: 2.298 ± 0.459
0.574ProMet: 0.574 ± 0.27
2.872ProAsn: 2.872 ± 0.189
0.574ProPro: 0.574 ± 0.27
2.298ProGln: 2.298 ± 0.459
1.149ProArg: 1.149 ± 0.54
2.298ProSer: 2.298 ± 0.459
3.446ProThr: 3.446 ± 2.999
2.872ProVal: 2.872 ± 1.729
0.574ProTrp: 0.574 ± 1.27
1.723ProTyr: 1.723 ± 0.811
0.0ProXaa: 0.0 ± 0.0
Gln
5.169GlnAla: 5.169 ± 3.728
1.723GlnCys: 1.723 ± 0.811
5.169GlnAsp: 5.169 ± 2.432
0.574GlnGlu: 0.574 ± 0.27
1.723GlnPhe: 1.723 ± 0.811
3.446GlnGly: 3.446 ± 0.081
1.149GlnHis: 1.149 ± 1.0
5.169GlnIle: 5.169 ± 0.648
4.595GlnLys: 4.595 ± 0.622
5.744GlnLeu: 5.744 ± 2.702
1.723GlnMet: 1.723 ± 0.729
2.298GlnAsn: 2.298 ± 1.081
4.595GlnPro: 4.595 ± 0.918
3.446GlnGln: 3.446 ± 1.459
3.446GlnArg: 3.446 ± 0.081
2.872GlnSer: 2.872 ± 1.351
1.723GlnThr: 1.723 ± 0.729
5.169GlnVal: 5.169 ± 5.268
1.723GlnTrp: 1.723 ± 0.811
1.149GlnTyr: 1.149 ± 0.54
0.0GlnXaa: 0.0 ± 0.0
Arg
3.446ArgAla: 3.446 ± 1.621
0.574ArgCys: 0.574 ± 0.27
2.872ArgAsp: 2.872 ± 0.189
1.723ArgGlu: 1.723 ± 0.729
2.298ArgPhe: 2.298 ± 1.081
1.149ArgGly: 1.149 ± 0.54
0.0ArgHis: 0.0 ± 0.0
1.723ArgIle: 1.723 ± 0.729
2.298ArgLys: 2.298 ± 0.459
2.872ArgLeu: 2.872 ± 1.351
1.149ArgMet: 1.149 ± 1.0
0.574ArgAsn: 0.574 ± 0.27
2.298ArgPro: 2.298 ± 0.459
3.446ArgGln: 3.446 ± 0.081
1.723ArgArg: 1.723 ± 0.811
1.149ArgSer: 1.149 ± 1.0
2.298ArgThr: 2.298 ± 1.081
3.446ArgVal: 3.446 ± 1.621
0.0ArgTrp: 0.0 ± 0.0
4.021ArgTyr: 4.021 ± 1.892
0.0ArgXaa: 0.0 ± 0.0
Ser
0.574SerAla: 0.574 ± 0.27
1.723SerCys: 1.723 ± 0.811
3.446SerAsp: 3.446 ± 0.081
2.298SerGlu: 2.298 ± 1.081
5.169SerPhe: 5.169 ± 2.432
5.744SerGly: 5.744 ± 0.378
0.574SerHis: 0.574 ± 0.27
2.298SerIle: 2.298 ± 0.459
5.169SerLys: 5.169 ± 2.432
10.339SerLeu: 10.339 ± 0.244
1.149SerMet: 1.149 ± 1.0
4.021SerAsn: 4.021 ± 1.892
1.723SerPro: 1.723 ± 0.729
1.149SerGln: 1.149 ± 0.54
2.872SerArg: 2.872 ± 1.351
4.595SerSer: 4.595 ± 0.918
2.872SerThr: 2.872 ± 1.729
9.765SerVal: 9.765 ± 1.566
1.723SerTrp: 1.723 ± 0.811
1.723SerTyr: 1.723 ± 0.729
0.0SerXaa: 0.0 ± 0.0
Thr
4.021ThrAla: 4.021 ± 4.268
1.149ThrCys: 1.149 ± 2.54
4.595ThrAsp: 4.595 ± 2.458
1.723ThrGlu: 1.723 ± 0.729
5.744ThrPhe: 5.744 ± 1.162
2.872ThrGly: 2.872 ± 1.729
0.574ThrHis: 0.574 ± 0.27
4.595ThrIle: 4.595 ± 0.622
2.872ThrLys: 2.872 ± 0.189
4.021ThrLeu: 4.021 ± 2.728
2.298ThrMet: 2.298 ± 1.081
2.872ThrAsn: 2.872 ± 1.729
1.723ThrPro: 1.723 ± 2.269
4.595ThrGln: 4.595 ± 0.918
3.446ThrArg: 3.446 ± 1.621
1.723ThrSer: 1.723 ± 0.811
4.595ThrThr: 4.595 ± 7.078
4.021ThrVal: 4.021 ± 1.188
0.0ThrTrp: 0.0 ± 0.0
1.723ThrTyr: 1.723 ± 2.269
0.0ThrXaa: 0.0 ± 0.0
Val
4.021ValAla: 4.021 ± 1.188
2.298ValCys: 2.298 ± 1.081
2.872ValAsp: 2.872 ± 0.189
3.446ValGlu: 3.446 ± 1.621
2.298ValPhe: 2.298 ± 1.081
4.021ValGly: 4.021 ± 1.188
2.298ValHis: 2.298 ± 1.081
5.169ValIle: 5.169 ± 0.648
4.595ValLys: 4.595 ± 2.162
7.467ValLeu: 7.467 ± 0.433
2.872ValMet: 2.872 ± 3.269
2.298ValAsn: 2.298 ± 1.081
2.298ValPro: 2.298 ± 0.459
5.169ValGln: 5.169 ± 0.648
2.872ValArg: 2.872 ± 0.189
6.893ValSer: 6.893 ± 0.163
3.446ValThr: 3.446 ± 4.539
6.893ValVal: 6.893 ± 1.377
0.0ValTrp: 0.0 ± 0.0
4.595ValTyr: 4.595 ± 0.918
0.0ValXaa: 0.0 ± 0.0
Trp
0.574TrpAla: 0.574 ± 0.27
1.149TrpCys: 1.149 ± 0.54
1.149TrpAsp: 1.149 ± 0.54
0.574TrpGlu: 0.574 ± 0.27
1.149TrpPhe: 1.149 ± 1.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.723TrpIle: 1.723 ± 0.811
1.723TrpLys: 1.723 ± 0.811
1.723TrpLeu: 1.723 ± 0.811
0.0TrpMet: 0.0 ± 0.0
0.574TrpAsn: 0.574 ± 0.27
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.149TrpTyr: 1.149 ± 0.54
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.595TyrAla: 4.595 ± 0.918
1.149TyrCys: 1.149 ± 0.54
4.595TyrAsp: 4.595 ± 2.458
2.872TyrGlu: 2.872 ± 1.729
2.872TyrPhe: 2.872 ± 1.351
1.723TyrGly: 1.723 ± 0.729
0.574TyrHis: 0.574 ± 0.27
5.169TyrIle: 5.169 ± 0.648
5.169TyrLys: 5.169 ± 2.188
2.298TyrLeu: 2.298 ± 1.081
4.021TyrMet: 4.021 ± 1.188
3.446TyrAsn: 3.446 ± 1.459
1.149TyrPro: 1.149 ± 0.54
2.872TyrGln: 2.872 ± 0.189
1.723TyrArg: 1.723 ± 0.811
2.872TyrSer: 2.872 ± 0.189
4.021TyrThr: 4.021 ± 1.892
3.446TyrVal: 3.446 ± 1.621
0.0TyrTrp: 0.0 ± 0.0
2.298TyrTyr: 2.298 ± 1.081
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1742 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski