Amino acid dipepetide frequency for Calidifontibacter indicus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.702AlaAla: 18.702 ± 0.204	0.949AlaCys: 0.949 ± 0.027	8.716AlaAsp: 8.716 ± 0.102	7.073AlaGlu: 7.073 ± 0.093	3.384AlaPhe: 3.384 ± 0.068	11.814AlaGly: 11.814 ± 0.123	2.513AlaHis: 2.513 ± 0.052	4.872AlaIle: 4.872 ± 0.067	3.571AlaLys: 3.571 ± 0.077	12.432AlaLeu: 12.432 ± 0.159	2.974AlaMet: 2.974 ± 0.051	2.316AlaAsn: 2.316 ± 0.055	5.99AlaPro: 5.99 ± 0.093	4.324AlaGln: 4.324 ± 0.068	8.541AlaArg: 8.541 ± 0.111	6.421AlaSer: 6.421 ± 0.089	7.795AlaThr: 7.795 ± 0.092	10.842AlaVal: 10.842 ± 0.132	1.653AlaTrp: 1.653 ± 0.043	2.412AlaTyr: 2.412 ± 0.043	0.0AlaXaa: 0.0 ± 0.0
Cys	0.964CysAla: 0.964 ± 0.031	0.105CysCys: 0.105 ± 0.011	0.544CysAsp: 0.544 ± 0.022	0.388CysGlu: 0.388 ± 0.02	0.229CysPhe: 0.229 ± 0.014	0.852CysGly: 0.852 ± 0.034	0.184CysHis: 0.184 ± 0.013	0.247CysIle: 0.247 ± 0.015	0.133CysLys: 0.133 ± 0.01	0.646CysLeu: 0.646 ± 0.023	0.117CysMet: 0.117 ± 0.01	0.161CysAsn: 0.161 ± 0.013	0.439CysPro: 0.439 ± 0.023	0.162CysGln: 0.162 ± 0.011	0.518CysArg: 0.518 ± 0.021	0.402CysSer: 0.402 ± 0.019	0.502CysThr: 0.502 ± 0.022	0.643CysVal: 0.643 ± 0.025	0.132CysTrp: 0.132 ± 0.012	0.153CysTyr: 0.153 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	8.157AspAla: 8.157 ± 0.11	0.41AspCys: 0.41 ± 0.017	5.058AspAsp: 5.058 ± 0.084	4.62AspGlu: 4.62 ± 0.074	1.753AspPhe: 1.753 ± 0.045	6.153AspGly: 6.153 ± 0.086	1.578AspHis: 1.578 ± 0.043	2.231AspIle: 2.231 ± 0.056	1.608AspLys: 1.608 ± 0.05	6.959AspLeu: 6.959 ± 0.089	0.927AspMet: 0.927 ± 0.028	1.256AspAsn: 1.256 ± 0.037	4.294AspPro: 4.294 ± 0.072	1.947AspGln: 1.947 ± 0.05	4.867AspArg: 4.867 ± 0.073	2.963AspSer: 2.963 ± 0.05	3.091AspThr: 3.091 ± 0.057	5.457AspVal: 5.457 ± 0.075	0.942AspTrp: 0.942 ± 0.029	1.21AspTyr: 1.21 ± 0.036	0.0AspXaa: 0.0 ± 0.0
Glu	6.337GluAla: 6.337 ± 0.077	0.376GluCys: 0.376 ± 0.019	2.219GluAsp: 2.219 ± 0.048	2.614GluGlu: 2.614 ± 0.058	1.709GluPhe: 1.709 ± 0.043	3.851GluGly: 3.851 ± 0.07	1.685GluHis: 1.685 ± 0.039	2.482GluIle: 2.482 ± 0.053	1.473GluLys: 1.473 ± 0.042	6.391GluLeu: 6.391 ± 0.084	0.981GluMet: 0.981 ± 0.028	1.009GluAsn: 1.009 ± 0.033	3.089GluPro: 3.089 ± 0.065	2.733GluGln: 2.733 ± 0.059	4.861GluArg: 4.861 ± 0.088	2.812GluSer: 2.812 ± 0.049	2.74GluThr: 2.74 ± 0.055	4.964GluVal: 4.964 ± 0.066	0.785GluTrp: 0.785 ± 0.028	0.992GluTyr: 0.992 ± 0.03	0.0GluXaa: 0.0 ± 0.0
Phe	3.845PheAla: 3.845 ± 0.056	0.242PheCys: 0.242 ± 0.016	2.269PheAsp: 2.269 ± 0.044	1.663PheGlu: 1.663 ± 0.046	0.916PhePhe: 0.916 ± 0.032	3.34PheGly: 3.34 ± 0.069	0.595PheHis: 0.595 ± 0.023	0.871PheIle: 0.871 ± 0.032	0.615PheLys: 0.615 ± 0.029	2.377PheLeu: 2.377 ± 0.053	0.464PheMet: 0.464 ± 0.02	0.685PheAsn: 0.685 ± 0.025	1.27PhePro: 1.27 ± 0.036	0.679PheGln: 0.679 ± 0.025	1.655PheArg: 1.655 ± 0.039	1.535PheSer: 1.535 ± 0.041	1.874PheThr: 1.874 ± 0.042	2.856PheVal: 2.856 ± 0.054	0.451PheTrp: 0.451 ± 0.022	0.559PheTyr: 0.559 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	10.26GlyAla: 10.26 ± 0.11	0.839GlyCys: 0.839 ± 0.026	5.397GlyAsp: 5.397 ± 0.076	4.779GlyGlu: 4.779 ± 0.069	3.028GlyPhe: 3.028 ± 0.063	7.937GlyGly: 7.937 ± 0.115	2.015GlyHis: 2.015 ± 0.049	3.72GlyIle: 3.72 ± 0.066	2.666GlyLys: 2.666 ± 0.051	8.814GlyLeu: 8.814 ± 0.115	2.051GlyMet: 2.051 ± 0.048	1.93GlyAsn: 1.93 ± 0.052	3.836GlyPro: 3.836 ± 0.066	2.916GlyGln: 2.916 ± 0.069	6.839GlyArg: 6.839 ± 0.085	5.648GlySer: 5.648 ± 0.088	5.535GlyThr: 5.535 ± 0.09	7.744GlyVal: 7.744 ± 0.09	1.693GlyTrp: 1.693 ± 0.04	2.271GlyTyr: 2.271 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	2.431HisAla: 2.431 ± 0.052	0.186HisCys: 0.186 ± 0.013	1.671HisAsp: 1.671 ± 0.039	1.265HisGlu: 1.265 ± 0.036	0.548HisPhe: 0.548 ± 0.02	2.059HisGly: 2.059 ± 0.042	0.721HisHis: 0.721 ± 0.029	0.686HisIle: 0.686 ± 0.026	0.397HisLys: 0.397 ± 0.022	2.303HisLeu: 2.303 ± 0.044	0.344HisMet: 0.344 ± 0.017	0.403HisAsn: 0.403 ± 0.021	1.544HisPro: 1.544 ± 0.041	0.672HisGln: 0.672 ± 0.024	1.918HisArg: 1.918 ± 0.043	1.035HisSer: 1.035 ± 0.035	1.246HisThr: 1.246 ± 0.036	1.792HisVal: 1.792 ± 0.037	0.333HisTrp: 0.333 ± 0.017	0.448HisTyr: 0.448 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	5.772IleAla: 5.772 ± 0.084	0.366IleCys: 0.366 ± 0.018	3.259IleAsp: 3.259 ± 0.05	2.516IleGlu: 2.516 ± 0.064	1.014IlePhe: 1.014 ± 0.035	4.271IleGly: 4.271 ± 0.078	0.707IleHis: 0.707 ± 0.027	1.303IleIle: 1.303 ± 0.038	0.983IleLys: 0.983 ± 0.039	2.643IleLeu: 2.643 ± 0.062	0.56IleMet: 0.56 ± 0.025	0.934IleAsn: 0.934 ± 0.03	1.863IlePro: 1.863 ± 0.045	0.81IleGln: 0.81 ± 0.031	2.382IleArg: 2.382 ± 0.047	2.087IleSer: 2.087 ± 0.045	2.664IleThr: 2.664 ± 0.056	3.707IleVal: 3.707 ± 0.059	0.445IleTrp: 0.445 ± 0.019	0.723IleTyr: 0.723 ± 0.025	0.0IleXaa: 0.0 ± 0.0
Lys	3.209LysAla: 3.209 ± 0.072	0.122LysCys: 0.122 ± 0.013	1.591LysAsp: 1.591 ± 0.05	1.169LysGlu: 1.169 ± 0.039	0.619LysPhe: 0.619 ± 0.024	2.008LysGly: 2.008 ± 0.048	0.61LysHis: 0.61 ± 0.026	1.086LysIle: 1.086 ± 0.037	1.031LysLys: 1.031 ± 0.048	2.241LysLeu: 2.241 ± 0.056	0.497LysMet: 0.497 ± 0.028	0.671LysAsn: 0.671 ± 0.031	1.486LysPro: 1.486 ± 0.048	1.005LysGln: 1.005 ± 0.032	1.702LysArg: 1.702 ± 0.045	1.417LysSer: 1.417 ± 0.044	1.558LysThr: 1.558 ± 0.05	2.545LysVal: 2.545 ± 0.062	0.333LysTrp: 0.333 ± 0.018	0.601LysTyr: 0.601 ± 0.024	0.0LysXaa: 0.0 ± 0.0
Leu	13.486LeuAla: 13.486 ± 0.136	0.724LeuCys: 0.724 ± 0.023	6.766LeuAsp: 6.766 ± 0.1	4.761LeuGlu: 4.761 ± 0.077	2.485LeuPhe: 2.485 ± 0.057	8.846LeuGly: 8.846 ± 0.099	2.026LeuHis: 2.026 ± 0.041	3.726LeuIle: 3.726 ± 0.068	2.139LeuLys: 2.139 ± 0.054	9.604LeuLeu: 9.604 ± 0.13	1.73LeuMet: 1.73 ± 0.039	1.798LeuAsn: 1.798 ± 0.044	5.551LeuPro: 5.551 ± 0.081	2.684LeuGln: 2.684 ± 0.047	7.725LeuArg: 7.725 ± 0.101	5.16LeuSer: 5.16 ± 0.073	6.14LeuThr: 6.14 ± 0.077	9.343LeuVal: 9.343 ± 0.124	1.187LeuTrp: 1.187 ± 0.034	1.45LeuTyr: 1.45 ± 0.037	0.0LeuXaa: 0.0 ± 0.0
Met	2.331MetAla: 2.331 ± 0.047	0.18MetCys: 0.18 ± 0.016	0.886MetAsp: 0.886 ± 0.031	0.723MetGlu: 0.723 ± 0.026	0.616MetPhe: 0.616 ± 0.027	1.524MetGly: 1.524 ± 0.042	0.391MetHis: 0.391 ± 0.019	0.792MetIle: 0.792 ± 0.031	0.579MetLys: 0.579 ± 0.026	2.008MetLeu: 2.008 ± 0.048	0.339MetMet: 0.339 ± 0.02	0.599MetAsn: 0.599 ± 0.021	1.212MetPro: 1.212 ± 0.039	0.591MetGln: 0.591 ± 0.028	1.491MetArg: 1.491 ± 0.036	1.627MetSer: 1.627 ± 0.039	1.827MetThr: 1.827 ± 0.044	1.598MetVal: 1.598 ± 0.043	0.228MetTrp: 0.228 ± 0.014	0.321MetTyr: 0.321 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	2.472AsnAla: 2.472 ± 0.05	0.157AsnCys: 0.157 ± 0.013	1.213AsnAsp: 1.213 ± 0.031	0.979AsnGlu: 0.979 ± 0.032	0.558AsnPhe: 0.558 ± 0.023	1.936AsnGly: 1.936 ± 0.054	0.458AsnHis: 0.458 ± 0.021	0.77AsnIle: 0.77 ± 0.029	0.565AsnLys: 0.565 ± 0.029	1.992AsnLeu: 1.992 ± 0.043	0.354AsnMet: 0.354 ± 0.016	0.561AsnAsn: 0.561 ± 0.026	1.624AsnPro: 1.624 ± 0.04	0.688AsnGln: 0.688 ± 0.029	1.345AsnArg: 1.345 ± 0.036	1.166AsnSer: 1.166 ± 0.04	1.183AsnThr: 1.183 ± 0.037	1.773AsnVal: 1.773 ± 0.046	0.342AsnTrp: 0.342 ± 0.019	0.487AsnTyr: 0.487 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	6.766ProAla: 6.766 ± 0.105	0.276ProCys: 0.276 ± 0.015	4.203ProAsp: 4.203 ± 0.069	3.433ProGlu: 3.433 ± 0.06	1.531ProPhe: 1.531 ± 0.035	5.194ProGly: 5.194 ± 0.075	1.182ProHis: 1.182 ± 0.032	1.936ProIle: 1.936 ± 0.04	1.454ProLys: 1.454 ± 0.044	4.489ProLeu: 4.489 ± 0.064	1.131ProMet: 1.131 ± 0.031	1.183ProAsn: 1.183 ± 0.03	2.388ProPro: 2.388 ± 0.063	1.917ProGln: 1.917 ± 0.039	3.22ProArg: 3.22 ± 0.066	3.343ProSer: 3.343 ± 0.07	3.722ProThr: 3.722 ± 0.069	4.767ProVal: 4.767 ± 0.075	0.903ProTrp: 0.903 ± 0.031	1.105ProTyr: 1.105 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	3.871GlnAla: 3.871 ± 0.064	0.184GlnCys: 0.184 ± 0.014	1.408GlnAsp: 1.408 ± 0.033	1.553GlnGlu: 1.553 ± 0.041	0.869GlnPhe: 0.869 ± 0.031	2.39GlnGly: 2.39 ± 0.051	0.816GlnHis: 0.816 ± 0.029	1.518GlnIle: 1.518 ± 0.041	0.73GlnLys: 0.73 ± 0.032	3.428GlnLeu: 3.428 ± 0.064	0.699GlnMet: 0.699 ± 0.028	0.621GlnAsn: 0.621 ± 0.03	1.92GlnPro: 1.92 ± 0.045	1.706GlnGln: 1.706 ± 0.058	2.694GlnArg: 2.694 ± 0.047	1.484GlnSer: 1.484 ± 0.046	1.734GlnThr: 1.734 ± 0.04	3.173GlnVal: 3.173 ± 0.057	0.614GlnTrp: 0.614 ± 0.025	0.671GlnTyr: 0.671 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	8.443ArgAla: 8.443 ± 0.101	0.527ArgCys: 0.527 ± 0.022	4.45ArgAsp: 4.45 ± 0.077	4.206ArgGlu: 4.206 ± 0.075	2.271ArgPhe: 2.271 ± 0.049	5.393ArgGly: 5.393 ± 0.082	1.604ArgHis: 1.604 ± 0.044	3.252ArgIle: 3.252 ± 0.055	1.816ArgLys: 1.816 ± 0.039	7.34ArgLeu: 7.34 ± 0.112	1.861ArgMet: 1.861 ± 0.049	1.413ArgAsn: 1.413 ± 0.035	4.12ArgPro: 4.12 ± 0.07	2.243ArgGln: 2.243 ± 0.051	6.669ArgArg: 6.669 ± 0.087	4.505ArgSer: 4.505 ± 0.066	4.633ArgThr: 4.633 ± 0.063	5.816ArgVal: 5.816 ± 0.073	1.282ArgTrp: 1.282 ± 0.038	1.536ArgTyr: 1.536 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	7.157SerAla: 7.157 ± 0.088	0.395SerCys: 0.395 ± 0.022	3.273SerAsp: 3.273 ± 0.057	2.425SerGlu: 2.425 ± 0.054	1.743SerPhe: 1.743 ± 0.042	5.776SerGly: 5.776 ± 0.077	1.002SerHis: 1.002 ± 0.029	2.16SerIle: 2.16 ± 0.044	1.319SerLys: 1.319 ± 0.038	5.015SerLeu: 5.015 ± 0.07	1.421SerMet: 1.421 ± 0.039	1.177SerAsn: 1.177 ± 0.035	3.064SerPro: 3.064 ± 0.064	1.632SerGln: 1.632 ± 0.044	3.713SerArg: 3.713 ± 0.065	3.781SerSer: 3.781 ± 0.099	4.029SerThr: 4.029 ± 0.082	4.614SerVal: 4.614 ± 0.073	0.938SerTrp: 0.938 ± 0.028	1.247SerTyr: 1.247 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	7.659ThrAla: 7.659 ± 0.105	0.458ThrCys: 0.458 ± 0.021	4.156ThrAsp: 4.156 ± 0.074	3.037ThrGlu: 3.037 ± 0.053	1.902ThrPhe: 1.902 ± 0.043	6.113ThrGly: 6.113 ± 0.087	1.259ThrHis: 1.259 ± 0.031	2.505ThrIle: 2.505 ± 0.053	1.602ThrLys: 1.602 ± 0.05	5.473ThrLeu: 5.473 ± 0.077	1.179ThrMet: 1.179 ± 0.032	1.365ThrAsn: 1.365 ± 0.038	3.769ThrPro: 3.769 ± 0.069	1.674ThrGln: 1.674 ± 0.046	3.859ThrArg: 3.859 ± 0.063	3.828ThrSer: 3.828 ± 0.078	4.378ThrThr: 4.378 ± 0.089	5.966ThrVal: 5.966 ± 0.083	0.999ThrTrp: 0.999 ± 0.029	1.355ThrTyr: 1.355 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	11.426ValAla: 11.426 ± 0.122	0.692ValCys: 0.692 ± 0.027	6.143ValAsp: 6.143 ± 0.076	5.146ValGlu: 5.146 ± 0.071	2.397ValPhe: 2.397 ± 0.049	7.438ValGly: 7.438 ± 0.099	1.934ValHis: 1.934 ± 0.044	3.638ValIle: 3.638 ± 0.058	1.993ValLys: 1.993 ± 0.057	9.344ValLeu: 9.344 ± 0.131	1.658ValMet: 1.658 ± 0.041	1.71ValAsn: 1.71 ± 0.042	4.867ValPro: 4.867 ± 0.062	2.561ValGln: 2.561 ± 0.045	6.675ValArg: 6.675 ± 0.08	4.642ValSer: 4.642 ± 0.067	5.839ValThr: 5.839 ± 0.085	9.304ValVal: 9.304 ± 0.127	1.142ValTrp: 1.142 ± 0.032	1.331ValTyr: 1.331 ± 0.033	0.0ValXaa: 0.0 ± 0.0
Trp	1.618TrpAla: 1.618 ± 0.037	0.171TrpCys: 0.171 ± 0.012	0.792TrpAsp: 0.792 ± 0.022	0.613TrpGlu: 0.613 ± 0.024	0.567TrpPhe: 0.567 ± 0.027	1.053TrpGly: 1.053 ± 0.031	0.39TrpHis: 0.39 ± 0.019	0.64TrpIle: 0.64 ± 0.024	0.365TrpLys: 0.365 ± 0.019	1.681TrpLeu: 1.681 ± 0.039	0.331TrpMet: 0.331 ± 0.018	0.386TrpAsn: 0.386 ± 0.019	0.756TrpPro: 0.756 ± 0.028	0.598TrpGln: 0.598 ± 0.022	1.207TrpArg: 1.207 ± 0.041	1.007TrpSer: 1.007 ± 0.032	1.018TrpThr: 1.018 ± 0.032	1.225TrpVal: 1.225 ± 0.035	0.395TrpTrp: 0.395 ± 0.021	0.286TrpTyr: 0.286 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.389TyrAla: 2.389 ± 0.047	0.159TyrCys: 0.159 ± 0.011	1.469TyrAsp: 1.469 ± 0.033	1.141TyrGlu: 1.141 ± 0.034	0.624TyrPhe: 0.624 ± 0.025	1.97TyrGly: 1.97 ± 0.047	0.334TyrHis: 0.334 ± 0.019	0.572TyrIle: 0.572 ± 0.022	0.464TyrLys: 0.464 ± 0.023	2.15TyrLeu: 2.15 ± 0.042	0.243TyrMet: 0.243 ± 0.015	0.447TyrAsn: 0.447 ± 0.024	1.058TyrPro: 1.058 ± 0.032	0.541TyrGln: 0.541 ± 0.024	1.497TyrArg: 1.497 ± 0.042	1.018TyrSer: 1.018 ± 0.033	1.029TyrThr: 1.029 ± 0.035	1.749TyrVal: 1.749 ± 0.041	0.305TyrTrp: 0.305 ± 0.018	0.434TyrTyr: 0.434 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3252 proteins (1062579 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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