Amino acid dipepetide frequency for Stenotrophomonas koreensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.388AlaAla: 19.388 ± 0.224	1.308AlaCys: 1.308 ± 0.044	7.696AlaAsp: 7.696 ± 0.106	6.878AlaGlu: 6.878 ± 0.113	3.65AlaPhe: 3.65 ± 0.062	12.611AlaGly: 12.611 ± 0.139	2.683AlaHis: 2.683 ± 0.07	5.493AlaIle: 5.493 ± 0.086	2.685AlaLys: 2.685 ± 0.087	16.297AlaLeu: 16.297 ± 0.205	3.313AlaMet: 3.313 ± 0.063	3.205AlaAsn: 3.205 ± 0.068	5.921AlaPro: 5.921 ± 0.099	6.913AlaGln: 6.913 ± 0.112	9.874AlaArg: 9.874 ± 0.121	6.958AlaSer: 6.958 ± 0.101	5.862AlaThr: 5.862 ± 0.092	9.199AlaVal: 9.199 ± 0.13	2.091AlaTrp: 2.091 ± 0.059	2.41AlaTyr: 2.41 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	1.105CysAla: 1.105 ± 0.04	0.113CysCys: 0.113 ± 0.011	0.466CysAsp: 0.466 ± 0.023	0.414CysGlu: 0.414 ± 0.023	0.281CysPhe: 0.281 ± 0.019	0.964CysGly: 0.964 ± 0.037	0.233CysHis: 0.233 ± 0.018	0.362CysIle: 0.362 ± 0.026	0.153CysLys: 0.153 ± 0.014	0.94CysLeu: 0.94 ± 0.04	0.153CysMet: 0.153 ± 0.014	0.22CysAsn: 0.22 ± 0.014	0.446CysPro: 0.446 ± 0.024	0.395CysGln: 0.395 ± 0.024	0.631CysArg: 0.631 ± 0.034	0.495CysSer: 0.495 ± 0.022	0.456CysThr: 0.456 ± 0.023	0.655CysVal: 0.655 ± 0.031	0.133CysTrp: 0.133 ± 0.014	0.205CysTyr: 0.205 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	7.457AspAla: 7.457 ± 0.098	0.477AspCys: 0.477 ± 0.023	2.797AspAsp: 2.797 ± 0.058	2.799AspGlu: 2.799 ± 0.07	1.903AspPhe: 1.903 ± 0.048	5.644AspGly: 5.644 ± 0.09	1.149AspHis: 1.149 ± 0.039	2.423AspIle: 2.423 ± 0.061	1.575AspLys: 1.575 ± 0.06	5.264AspLeu: 5.264 ± 0.093	1.112AspMet: 1.112 ± 0.032	1.609AspAsn: 1.609 ± 0.047	3.283AspPro: 3.283 ± 0.064	2.013AspGln: 2.013 ± 0.049	3.408AspArg: 3.408 ± 0.066	2.638AspSer: 2.638 ± 0.059	2.555AspThr: 2.555 ± 0.064	3.725AspVal: 3.725 ± 0.072	1.032AspTrp: 1.032 ± 0.031	1.578AspTyr: 1.578 ± 0.047	0.0AspXaa: 0.0 ± 0.0
Glu	6.185GluAla: 6.185 ± 0.099	0.314GluCys: 0.314 ± 0.022	2.252GluAsp: 2.252 ± 0.059	2.309GluGlu: 2.309 ± 0.059	1.537GluPhe: 1.537 ± 0.046	3.781GluGly: 3.781 ± 0.072	1.432GluHis: 1.432 ± 0.043	2.212GluIle: 2.212 ± 0.066	1.533GluLys: 1.533 ± 0.051	6.216GluLeu: 6.216 ± 0.089	1.005GluMet: 1.005 ± 0.034	1.254GluAsn: 1.254 ± 0.04	2.331GluPro: 2.331 ± 0.061	3.649GluGln: 3.649 ± 0.079	4.405GluArg: 4.405 ± 0.092	2.024GluSer: 2.024 ± 0.047	2.001GluThr: 2.001 ± 0.052	3.821GluVal: 3.821 ± 0.072	0.502GluTrp: 0.502 ± 0.026	0.999GluTyr: 0.999 ± 0.037	0.0GluXaa: 0.0 ± 0.0
Phe	4.233PheAla: 4.233 ± 0.079	0.335PheCys: 0.335 ± 0.02	2.366PheAsp: 2.366 ± 0.058	1.792PheGlu: 1.792 ± 0.048	1.175PhePhe: 1.175 ± 0.04	3.123PheGly: 3.123 ± 0.065	0.738PheHis: 0.738 ± 0.031	1.392PheIle: 1.392 ± 0.045	0.816PheLys: 0.816 ± 0.033	2.7PheLeu: 2.7 ± 0.06	0.596PheMet: 0.596 ± 0.026	1.182PheAsn: 1.182 ± 0.041	1.318PhePro: 1.318 ± 0.042	1.036PheGln: 1.036 ± 0.035	1.671PheArg: 1.671 ± 0.048	2.072PheSer: 2.072 ± 0.054	1.559PheThr: 1.559 ± 0.047	2.28PheVal: 2.28 ± 0.05	0.481PheTrp: 0.481 ± 0.025	0.733PheTyr: 0.733 ± 0.029	0.0PheXaa: 0.0 ± 0.0
Gly	8.353GlyAla: 8.353 ± 0.12	0.87GlyCys: 0.87 ± 0.031	4.234GlyAsp: 4.234 ± 0.075	4.321GlyGlu: 4.321 ± 0.071	3.247GlyPhe: 3.247 ± 0.067	6.82GlyGly: 6.82 ± 0.123	2.157GlyHis: 2.157 ± 0.054	4.055GlyIle: 4.055 ± 0.082	2.933GlyLys: 2.933 ± 0.069	9.93GlyLeu: 9.93 ± 0.13	2.366GlyMet: 2.366 ± 0.059	2.666GlyAsn: 2.666 ± 0.065	3.219GlyPro: 3.219 ± 0.071	5.094GlyGln: 5.094 ± 0.091	6.205GlyArg: 6.205 ± 0.09	5.024GlySer: 5.024 ± 0.089	3.84GlyThr: 3.84 ± 0.076	6.212GlyVal: 6.212 ± 0.098	1.772GlyTrp: 1.772 ± 0.059	2.258GlyTyr: 2.258 ± 0.057	0.0GlyXaa: 0.0 ± 0.0
His	2.986HisAla: 2.986 ± 0.07	0.32HisCys: 0.32 ± 0.021	1.222HisAsp: 1.222 ± 0.039	1.019HisGlu: 1.019 ± 0.032	0.837HisPhe: 0.837 ± 0.034	2.303HisGly: 2.303 ± 0.064	0.659HisHis: 0.659 ± 0.03	0.908HisIle: 0.908 ± 0.034	0.463HisLys: 0.463 ± 0.026	2.24HisLeu: 2.24 ± 0.052	0.424HisMet: 0.424 ± 0.023	0.608HisAsn: 0.608 ± 0.026	1.455HisPro: 1.455 ± 0.048	0.923HisGln: 0.923 ± 0.033	1.585HisArg: 1.585 ± 0.048	1.095HisSer: 1.095 ± 0.036	1.079HisThr: 1.079 ± 0.039	1.458HisVal: 1.458 ± 0.045	0.538HisTrp: 0.538 ± 0.026	0.683HisTyr: 0.683 ± 0.032	0.0HisXaa: 0.0 ± 0.0
Ile	6.567IleAla: 6.567 ± 0.087	0.356IleCys: 0.356 ± 0.019	3.344IleAsp: 3.344 ± 0.06	2.81IleGlu: 2.81 ± 0.07	1.043IlePhe: 1.043 ± 0.033	4.356IleGly: 4.356 ± 0.079	0.93IleHis: 0.93 ± 0.037	1.634IleIle: 1.634 ± 0.047	1.276IleLys: 1.276 ± 0.042	3.015IleLeu: 3.015 ± 0.065	0.557IleMet: 0.557 ± 0.026	1.52IleAsn: 1.52 ± 0.048	1.937IlePro: 1.937 ± 0.054	1.348IleGln: 1.348 ± 0.041	2.327IleArg: 2.327 ± 0.057	2.347IleSer: 2.347 ± 0.05	2.455IleThr: 2.455 ± 0.062	2.977IleVal: 2.977 ± 0.062	0.443IleTrp: 0.443 ± 0.025	0.794IleTyr: 0.794 ± 0.033	0.0IleXaa: 0.0 ± 0.0
Lys	3.257LysAla: 3.257 ± 0.068	0.132LysCys: 0.132 ± 0.013	1.259LysAsp: 1.259 ± 0.049	0.988LysGlu: 0.988 ± 0.05	0.665LysPhe: 0.665 ± 0.03	1.812LysGly: 1.812 ± 0.057	0.558LysHis: 0.558 ± 0.026	1.107LysIle: 1.107 ± 0.042	0.898LysLys: 0.898 ± 0.06	2.818LysLeu: 2.818 ± 0.069	0.585LysMet: 0.585 ± 0.027	0.578LysAsn: 0.578 ± 0.028	1.592LysPro: 1.592 ± 0.051	1.144LysGln: 1.144 ± 0.041	1.912LysArg: 1.912 ± 0.054	1.19LysSer: 1.19 ± 0.042	1.301LysThr: 1.301 ± 0.046	2.054LysVal: 2.054 ± 0.062	0.257LysTrp: 0.257 ± 0.019	0.566LysTyr: 0.566 ± 0.026	0.0LysXaa: 0.0 ± 0.0
Leu	17.245LeuAla: 17.245 ± 0.191	1.15LeuCys: 1.15 ± 0.043	6.525LeuAsp: 6.525 ± 0.099	5.73LeuGlu: 5.73 ± 0.101	3.315LeuPhe: 3.315 ± 0.077	9.124LeuGly: 9.124 ± 0.135	2.533LeuHis: 2.533 ± 0.061	4.176LeuIle: 4.176 ± 0.075	2.749LeuLys: 2.749 ± 0.06	13.683LeuLeu: 13.683 ± 0.23	2.24LeuMet: 2.24 ± 0.054	2.377LeuAsn: 2.377 ± 0.063	7.269LeuPro: 7.269 ± 0.117	5.378LeuGln: 5.378 ± 0.1	8.546LeuArg: 8.546 ± 0.114	6.066LeuSer: 6.066 ± 0.096	4.765LeuThr: 4.765 ± 0.072	7.993LeuVal: 7.993 ± 0.112	1.626LeuTrp: 1.626 ± 0.047	2.257LeuTyr: 2.257 ± 0.053	0.0LeuXaa: 0.0 ± 0.0
Met	3.038MetAla: 3.038 ± 0.059	0.132MetCys: 0.132 ± 0.012	1.092MetAsp: 1.092 ± 0.04	0.861MetGlu: 0.861 ± 0.037	0.572MetPhe: 0.572 ± 0.026	1.554MetGly: 1.554 ± 0.047	0.457MetHis: 0.457 ± 0.019	0.882MetIle: 0.882 ± 0.033	0.679MetLys: 0.679 ± 0.032	2.396MetLeu: 2.396 ± 0.064	0.451MetMet: 0.451 ± 0.028	0.665MetAsn: 0.665 ± 0.026	1.339MetPro: 1.339 ± 0.046	0.992MetGln: 0.992 ± 0.037	1.587MetArg: 1.587 ± 0.044	1.564MetSer: 1.564 ± 0.042	1.265MetThr: 1.265 ± 0.036	1.456MetVal: 1.456 ± 0.045	0.193MetTrp: 0.193 ± 0.015	0.314MetTyr: 0.314 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.414AsnAla: 3.414 ± 0.07	0.214AsnCys: 0.214 ± 0.016	1.412AsnAsp: 1.412 ± 0.048	1.226AsnGlu: 1.226 ± 0.04	0.834AsnPhe: 0.834 ± 0.037	2.46AsnGly: 2.46 ± 0.053	0.617AsnHis: 0.617 ± 0.028	1.068AsnIle: 1.068 ± 0.039	0.697AsnLys: 0.697 ± 0.033	2.622AsnLeu: 2.622 ± 0.059	0.419AsnMet: 0.419 ± 0.021	0.765AsnAsn: 0.765 ± 0.035	1.963AsnPro: 1.963 ± 0.054	1.013AsnGln: 1.013 ± 0.039	1.84AsnArg: 1.84 ± 0.048	1.234AsnSer: 1.234 ± 0.042	1.425AsnThr: 1.425 ± 0.047	1.794AsnVal: 1.794 ± 0.052	0.4AsnTrp: 0.4 ± 0.025	0.675AsnTyr: 0.675 ± 0.028	0.0AsnXaa: 0.0 ± 0.0
Pro	8.544ProAla: 8.544 ± 0.143	0.331ProCys: 0.331 ± 0.023	3.059ProAsp: 3.059 ± 0.063	3.056ProGlu: 3.056 ± 0.066	1.547ProPhe: 1.547 ± 0.043	4.96ProGly: 4.96 ± 0.083	0.95ProHis: 0.95 ± 0.033	1.596ProIle: 1.596 ± 0.042	1.017ProLys: 1.017 ± 0.036	5.97ProLeu: 5.97 ± 0.1	1.251ProMet: 1.251 ± 0.04	1.05ProAsn: 1.05 ± 0.038	2.653ProPro: 2.653 ± 0.086	2.346ProGln: 2.346 ± 0.053	3.188ProArg: 3.188 ± 0.073	2.52ProSer: 2.52 ± 0.054	2.13ProThr: 2.13 ± 0.055	4.456ProVal: 4.456 ± 0.071	0.867ProTrp: 0.867 ± 0.032	1.125ProTyr: 1.125 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	8.118GlnAla: 8.118 ± 0.145	0.37GlnCys: 0.37 ± 0.02	1.601GlnAsp: 1.601 ± 0.049	1.532GlnGlu: 1.532 ± 0.048	1.368GlnPhe: 1.368 ± 0.043	3.412GlnGly: 3.412 ± 0.075	1.138GlnHis: 1.138 ± 0.034	1.919GlnIle: 1.919 ± 0.042	0.85GlnLys: 0.85 ± 0.032	6.398GlnLeu: 6.398 ± 0.106	1.081GlnMet: 1.081 ± 0.039	0.694GlnAsn: 0.694 ± 0.031	2.887GlnPro: 2.887 ± 0.066	3.447GlnGln: 3.447 ± 0.088	4.636GlnArg: 4.636 ± 0.095	1.774GlnSer: 1.774 ± 0.051	1.835GlnThr: 1.835 ± 0.049	4.208GlnVal: 4.208 ± 0.079	1.011GlnTrp: 1.011 ± 0.035	0.932GlnTyr: 0.932 ± 0.036	0.0GlnXaa: 0.0 ± 0.0
Arg	7.966ArgAla: 7.966 ± 0.112	0.571ArgCys: 0.571 ± 0.029	3.857ArgAsp: 3.857 ± 0.073	3.999ArgGlu: 3.999 ± 0.083	2.653ArgPhe: 2.653 ± 0.055	5.006ArgGly: 5.006 ± 0.08	1.874ArgHis: 1.874 ± 0.054	3.623ArgIle: 3.623 ± 0.066	1.749ArgLys: 1.749 ± 0.048	8.753ArgLeu: 8.753 ± 0.119	1.744ArgMet: 1.744 ± 0.042	2.053ArgAsn: 2.053 ± 0.052	3.334ArgPro: 3.334 ± 0.06	4.296ArgGln: 4.296 ± 0.081	5.309ArgArg: 5.309 ± 0.095	3.836ArgSer: 3.836 ± 0.066	2.799ArgThr: 2.799 ± 0.058	5.017ArgVal: 5.017 ± 0.087	1.463ArgTrp: 1.463 ± 0.046	2.131ArgTyr: 2.131 ± 0.056	0.0ArgXaa: 0.0 ± 0.0
Ser	6.665SerAla: 6.665 ± 0.098	0.438SerCys: 0.438 ± 0.023	2.644SerAsp: 2.644 ± 0.056	2.431SerGlu: 2.431 ± 0.053	1.761SerPhe: 1.761 ± 0.048	4.998SerGly: 4.998 ± 0.082	1.193SerHis: 1.193 ± 0.037	2.143SerIle: 2.143 ± 0.051	1.222SerLys: 1.222 ± 0.042	5.676SerLeu: 5.676 ± 0.094	0.994SerMet: 0.994 ± 0.037	1.493SerAsn: 1.493 ± 0.049	2.768SerPro: 2.768 ± 0.057	2.302SerGln: 2.302 ± 0.056	3.652SerArg: 3.652 ± 0.063	2.945SerSer: 2.945 ± 0.068	2.682SerThr: 2.682 ± 0.067	3.796SerVal: 3.796 ± 0.08	0.921SerTrp: 0.921 ± 0.033	1.315SerTyr: 1.315 ± 0.05	0.0SerXaa: 0.0 ± 0.0
Thr	6.142ThrAla: 6.142 ± 0.085	0.367ThrCys: 0.367 ± 0.02	2.32ThrAsp: 2.32 ± 0.051	1.978ThrGlu: 1.978 ± 0.058	1.374ThrPhe: 1.374 ± 0.039	4.425ThrGly: 4.425 ± 0.077	1.018ThrHis: 1.018 ± 0.037	1.944ThrIle: 1.944 ± 0.043	0.82ThrLys: 0.82 ± 0.037	5.711ThrLeu: 5.711 ± 0.079	0.751ThrMet: 0.751 ± 0.028	0.998ThrAsn: 0.998 ± 0.043	3.137ThrPro: 3.137 ± 0.06	1.613ThrGln: 1.613 ± 0.042	3.077ThrArg: 3.077 ± 0.061	2.232ThrSer: 2.232 ± 0.058	2.513ThrThr: 2.513 ± 0.062	3.698ThrVal: 3.698 ± 0.07	0.59ThrTrp: 0.59 ± 0.027	0.972ThrTyr: 0.972 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	9.627ValAla: 9.627 ± 0.135	0.673ValCys: 0.673 ± 0.028	4.394ValAsp: 4.394 ± 0.07	3.891ValGlu: 3.891 ± 0.07	2.472ValPhe: 2.472 ± 0.061	5.243ValGly: 5.243 ± 0.091	1.62ValHis: 1.62 ± 0.048	3.631ValIle: 3.631 ± 0.067	1.64ValLys: 1.64 ± 0.06	9.008ValLeu: 9.008 ± 0.121	1.655ValMet: 1.655 ± 0.048	2.026ValAsn: 2.026 ± 0.056	3.725ValPro: 3.725 ± 0.067	3.044ValGln: 3.044 ± 0.062	4.915ValArg: 4.915 ± 0.08	3.993ValSer: 3.993 ± 0.064	3.371ValThr: 3.371 ± 0.078	6.239ValVal: 6.239 ± 0.102	0.952ValTrp: 0.952 ± 0.039	1.448ValTyr: 1.448 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	1.445TrpAla: 1.445 ± 0.047	0.154TrpCys: 0.154 ± 0.015	0.697TrpAsp: 0.697 ± 0.025	0.67TrpGlu: 0.67 ± 0.024	0.566TrpPhe: 0.566 ± 0.027	0.934TrpGly: 0.934 ± 0.037	0.384TrpHis: 0.384 ± 0.023	0.676TrpIle: 0.676 ± 0.029	0.421TrpLys: 0.421 ± 0.024	2.6TrpLeu: 2.6 ± 0.077	0.421TrpMet: 0.421 ± 0.025	0.449TrpAsn: 0.449 ± 0.023	0.837TrpPro: 0.837 ± 0.031	1.231TrpGln: 1.231 ± 0.042	1.32TrpArg: 1.32 ± 0.044	0.821TrpSer: 0.821 ± 0.03	0.623TrpThr: 0.623 ± 0.027	1.049TrpVal: 1.049 ± 0.037	0.365TrpTrp: 0.365 ± 0.024	0.358TrpTyr: 0.358 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.703TyrAla: 2.703 ± 0.059	0.196TyrCys: 0.196 ± 0.018	1.203TyrAsp: 1.203 ± 0.047	1.056TyrGlu: 1.056 ± 0.033	0.796TyrPhe: 0.796 ± 0.028	2.046TyrGly: 2.046 ± 0.056	0.482TyrHis: 0.482 ± 0.023	0.793TyrIle: 0.793 ± 0.034	0.497TyrLys: 0.497 ± 0.024	2.513TyrLeu: 2.513 ± 0.052	0.368TyrMet: 0.368 ± 0.022	0.682TyrAsn: 0.682 ± 0.033	1.202TyrPro: 1.202 ± 0.037	1.034TyrGln: 1.034 ± 0.036	1.945TyrArg: 1.945 ± 0.051	1.209TyrSer: 1.209 ± 0.041	1.164TyrThr: 1.164 ± 0.035	1.48TyrVal: 1.48 ± 0.041	0.386TyrTrp: 0.386 ± 0.017	0.611TyrTyr: 0.611 ± 0.031	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2597 proteins (842727 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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