Amino acid dipepetide frequency for Phenylobacterium soli

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	22.801AlaAla: 22.801 ± 0.244	1.262AlaCys: 1.262 ± 0.038	7.62AlaAsp: 7.62 ± 0.084	9.302AlaGlu: 9.302 ± 0.129	4.865AlaPhe: 4.865 ± 0.07	12.809AlaGly: 12.809 ± 0.12	2.607AlaHis: 2.607 ± 0.047	5.432AlaIle: 5.432 ± 0.077	4.651AlaLys: 4.651 ± 0.08	14.552AlaLeu: 14.552 ± 0.143	3.561AlaMet: 3.561 ± 0.052	2.924AlaAsn: 2.924 ± 0.06	7.846AlaPro: 7.846 ± 0.104	4.849AlaGln: 4.849 ± 0.071	10.743AlaArg: 10.743 ± 0.135	6.461AlaSer: 6.461 ± 0.098	5.965AlaThr: 5.965 ± 0.1	9.644AlaVal: 9.644 ± 0.093	2.054AlaTrp: 2.054 ± 0.044	2.974AlaTyr: 2.974 ± 0.053	0.0AlaXaa: 0.0 ± 0.0
Cys	1.117CysAla: 1.117 ± 0.027	0.087CysCys: 0.087 ± 0.008	0.526CysAsp: 0.526 ± 0.019	0.455CysGlu: 0.455 ± 0.019	0.285CysPhe: 0.285 ± 0.016	0.904CysGly: 0.904 ± 0.029	0.211CysHis: 0.211 ± 0.014	0.26CysIle: 0.26 ± 0.014	0.161CysLys: 0.161 ± 0.012	0.672CysLeu: 0.672 ± 0.024	0.157CysMet: 0.157 ± 0.012	0.181CysAsn: 0.181 ± 0.014	0.44CysPro: 0.44 ± 0.02	0.227CysGln: 0.227 ± 0.015	0.571CysArg: 0.571 ± 0.021	0.348CysSer: 0.348 ± 0.019	0.358CysThr: 0.358 ± 0.019	0.6CysVal: 0.6 ± 0.022	0.1CysTrp: 0.1 ± 0.009	0.189CysTyr: 0.189 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	7.268AspAla: 7.268 ± 0.078	0.399AspCys: 0.399 ± 0.02	2.833AspAsp: 2.833 ± 0.06	3.481AspGlu: 3.481 ± 0.062	2.053AspPhe: 2.053 ± 0.038	5.108AspGly: 5.108 ± 0.084	1.28AspHis: 1.28 ± 0.032	2.224AspIle: 2.224 ± 0.049	1.557AspLys: 1.557 ± 0.038	6.263AspLeu: 6.263 ± 0.071	1.09AspMet: 1.09 ± 0.03	1.014AspAsn: 1.014 ± 0.033	4.066AspPro: 4.066 ± 0.069	1.895AspGln: 1.895 ± 0.042	4.379AspArg: 4.379 ± 0.063	1.79AspSer: 1.79 ± 0.044	2.313AspThr: 2.313 ± 0.057	4.164AspVal: 4.164 ± 0.06	1.03AspTrp: 1.03 ± 0.034	1.514AspTyr: 1.514 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	9.62GluAla: 9.62 ± 0.139	0.281GluCys: 0.281 ± 0.014	2.857GluAsp: 2.857 ± 0.052	3.084GluGlu: 3.084 ± 0.058	1.65GluPhe: 1.65 ± 0.034	4.899GluGly: 4.899 ± 0.066	1.199GluHis: 1.199 ± 0.031	3.039GluIle: 3.039 ± 0.051	1.951GluLys: 1.951 ± 0.049	5.703GluLeu: 5.703 ± 0.069	1.292GluMet: 1.292 ± 0.036	1.17GluAsn: 1.17 ± 0.034	3.217GluPro: 3.217 ± 0.052	1.905GluGln: 1.905 ± 0.044	5.3GluArg: 5.3 ± 0.083	2.092GluSer: 2.092 ± 0.041	3.322GluThr: 3.322 ± 0.053	4.418GluVal: 4.418 ± 0.062	0.715GluTrp: 0.715 ± 0.023	0.903GluTyr: 0.903 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	4.778PheAla: 4.778 ± 0.07	0.382PheCys: 0.382 ± 0.02	2.504PheAsp: 2.504 ± 0.051	2.226PheGlu: 2.226 ± 0.045	1.226PhePhe: 1.226 ± 0.034	3.629PheGly: 3.629 ± 0.055	0.73PheHis: 0.73 ± 0.022	1.266PheIle: 1.266 ± 0.035	1.003PheLys: 1.003 ± 0.03	2.991PheLeu: 2.991 ± 0.051	0.751PheMet: 0.751 ± 0.026	0.96PheAsn: 0.96 ± 0.026	1.521PhePro: 1.521 ± 0.037	1.045PheGln: 1.045 ± 0.028	2.147PheArg: 2.147 ± 0.043	1.882PheSer: 1.882 ± 0.045	1.947PheThr: 1.947 ± 0.051	2.597PheVal: 2.597 ± 0.047	0.529PheTrp: 0.529 ± 0.022	0.838PheTyr: 0.838 ± 0.029	0.0PheXaa: 0.0 ± 0.0
Gly	11.947GlyAla: 11.947 ± 0.113	0.833GlyCys: 0.833 ± 0.026	4.706GlyAsp: 4.706 ± 0.08	5.619GlyGlu: 5.619 ± 0.068	3.62GlyPhe: 3.62 ± 0.05	8.772GlyGly: 8.772 ± 0.133	1.809GlyHis: 1.809 ± 0.04	2.76GlyIle: 2.76 ± 0.048	2.992GlyLys: 2.992 ± 0.054	9.597GlyLeu: 9.597 ± 0.106	2.149GlyMet: 2.149 ± 0.048	1.627GlyAsn: 1.627 ± 0.056	4.518GlyPro: 4.518 ± 0.067	3.355GlyGln: 3.355 ± 0.055	7.113GlyArg: 7.113 ± 0.091	4.227GlySer: 4.227 ± 0.071	3.431GlyThr: 3.431 ± 0.075	7.589GlyVal: 7.589 ± 0.081	1.568GlyTrp: 1.568 ± 0.041	2.386GlyTyr: 2.386 ± 0.049	0.0GlyXaa: 0.0 ± 0.0
His	2.486HisAla: 2.486 ± 0.055	0.179HisCys: 0.179 ± 0.013	1.17HisAsp: 1.17 ± 0.04	1.102HisGlu: 1.102 ± 0.032	0.721HisPhe: 0.721 ± 0.028	1.885HisGly: 1.885 ± 0.046	0.503HisHis: 0.503 ± 0.023	0.705HisIle: 0.705 ± 0.024	0.45HisLys: 0.45 ± 0.022	1.964HisLeu: 1.964 ± 0.036	0.455HisMet: 0.455 ± 0.019	0.431HisAsn: 0.431 ± 0.021	1.417HisPro: 1.417 ± 0.034	0.559HisGln: 0.559 ± 0.022	1.447HisArg: 1.447 ± 0.034	0.728HisSer: 0.728 ± 0.026	0.789HisThr: 0.789 ± 0.024	1.492HisVal: 1.492 ± 0.035	0.331HisTrp: 0.331 ± 0.016	0.462HisTyr: 0.462 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	6.123IleAla: 6.123 ± 0.072	0.408IleCys: 0.408 ± 0.017	2.828IleAsp: 2.828 ± 0.05	2.884IleGlu: 2.884 ± 0.053	1.259IlePhe: 1.259 ± 0.03	3.939IleGly: 3.939 ± 0.064	0.709IleHis: 0.709 ± 0.023	1.31IleIle: 1.31 ± 0.04	1.107IleLys: 1.107 ± 0.028	3.774IleLeu: 3.774 ± 0.057	0.708IleMet: 0.708 ± 0.021	1.049IleAsn: 1.049 ± 0.029	1.934IlePro: 1.934 ± 0.035	1.133IleGln: 1.133 ± 0.035	2.765IleArg: 2.765 ± 0.054	2.197IleSer: 2.197 ± 0.042	2.133IleThr: 2.133 ± 0.042	3.319IleVal: 3.319 ± 0.056	0.55IleTrp: 0.55 ± 0.021	0.937IleTyr: 0.937 ± 0.03	0.0IleXaa: 0.0 ± 0.0
Lys	4.873LysAla: 4.873 ± 0.076	0.14LysCys: 0.14 ± 0.01	1.799LysAsp: 1.799 ± 0.044	1.324LysGlu: 1.324 ± 0.034	0.817LysPhe: 0.817 ± 0.029	2.888LysGly: 2.888 ± 0.055	0.502LysHis: 0.502 ± 0.022	1.466LysIle: 1.466 ± 0.035	1.108LysLys: 1.108 ± 0.042	3.166LysLeu: 3.166 ± 0.049	0.636LysMet: 0.636 ± 0.025	0.735LysAsn: 0.735 ± 0.032	2.251LysPro: 2.251 ± 0.049	0.819LysGln: 0.819 ± 0.026	2.243LysArg: 2.243 ± 0.05	1.492LysSer: 1.492 ± 0.036	1.935LysThr: 1.935 ± 0.037	2.664LysVal: 2.664 ± 0.05	0.344LysTrp: 0.344 ± 0.015	0.556LysTyr: 0.556 ± 0.025	0.0LysXaa: 0.0 ± 0.0
Leu	15.489LeuAla: 15.489 ± 0.166	0.766LeuCys: 0.766 ± 0.023	5.916LeuAsp: 5.916 ± 0.072	5.554LeuGlu: 5.554 ± 0.072	3.322LeuPhe: 3.322 ± 0.06	8.587LeuGly: 8.587 ± 0.101	1.783LeuHis: 1.783 ± 0.038	4.297LeuIle: 4.297 ± 0.068	4.025LeuLys: 4.025 ± 0.057	8.258LeuLeu: 8.258 ± 0.091	2.261LeuMet: 2.261 ± 0.041	2.393LeuAsn: 2.393 ± 0.061	5.233LeuPro: 5.233 ± 0.073	2.886LeuGln: 2.886 ± 0.054	6.657LeuArg: 6.657 ± 0.083	5.896LeuSer: 5.896 ± 0.098	5.773LeuThr: 5.773 ± 0.099	7.363LeuVal: 7.363 ± 0.091	1.2LeuTrp: 1.2 ± 0.033	2.021LeuTyr: 2.021 ± 0.039	0.0LeuXaa: 0.0 ± 0.0
Met	3.265MetAla: 3.265 ± 0.058	0.169MetCys: 0.169 ± 0.011	1.163MetAsp: 1.163 ± 0.03	1.013MetGlu: 1.013 ± 0.03	0.663MetPhe: 0.663 ± 0.024	1.955MetGly: 1.955 ± 0.044	0.365MetHis: 0.365 ± 0.017	1.05MetIle: 1.05 ± 0.034	0.885MetLys: 0.885 ± 0.028	2.0MetLeu: 2.0 ± 0.042	0.53MetMet: 0.53 ± 0.022	0.633MetAsn: 0.633 ± 0.023	1.192MetPro: 1.192 ± 0.027	0.634MetGln: 0.634 ± 0.024	1.687MetArg: 1.687 ± 0.041	1.563MetSer: 1.563 ± 0.038	1.665MetThr: 1.665 ± 0.04	1.429MetVal: 1.429 ± 0.036	0.214MetTrp: 0.214 ± 0.013	0.276MetTyr: 0.276 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	2.857AsnAla: 2.857 ± 0.054	0.207AsnCys: 0.207 ± 0.014	1.218AsnAsp: 1.218 ± 0.043	0.954AsnGlu: 0.954 ± 0.027	0.793AsnPhe: 0.793 ± 0.025	2.122AsnGly: 2.122 ± 0.053	0.411AsnHis: 0.411 ± 0.019	1.045AsnIle: 1.045 ± 0.033	0.502AsnLys: 0.502 ± 0.022	2.416AsnLeu: 2.416 ± 0.052	0.442AsnMet: 0.442 ± 0.02	0.555AsnAsn: 0.555 ± 0.029	1.678AsnPro: 1.678 ± 0.035	0.679AsnGln: 0.679 ± 0.026	1.513AsnArg: 1.513 ± 0.038	0.993AsnSer: 0.993 ± 0.034	1.175AsnThr: 1.175 ± 0.039	1.74AsnVal: 1.74 ± 0.043	0.354AsnTrp: 0.354 ± 0.017	0.597AsnTyr: 0.597 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	8.172ProAla: 8.172 ± 0.114	0.334ProCys: 0.334 ± 0.017	3.751ProAsp: 3.751 ± 0.051	4.017ProGlu: 4.017 ± 0.058	1.956ProPhe: 1.956 ± 0.044	5.159ProGly: 5.159 ± 0.071	1.115ProHis: 1.115 ± 0.028	2.256ProIle: 2.256 ± 0.037	2.067ProLys: 2.067 ± 0.046	4.891ProLeu: 4.891 ± 0.063	1.228ProMet: 1.228 ± 0.031	1.333ProAsn: 1.333 ± 0.031	3.82ProPro: 3.82 ± 0.112	1.992ProGln: 1.992 ± 0.039	3.404ProArg: 3.404 ± 0.058	2.685ProSer: 2.685 ± 0.048	2.803ProThr: 2.803 ± 0.053	4.216ProVal: 4.216 ± 0.064	0.788ProTrp: 0.788 ± 0.027	1.165ProTyr: 1.165 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	5.347GlnAla: 5.347 ± 0.076	0.177GlnCys: 0.177 ± 0.012	1.357GlnAsp: 1.357 ± 0.03	1.38GlnGlu: 1.38 ± 0.039	0.935GlnPhe: 0.935 ± 0.031	2.82GlnGly: 2.82 ± 0.051	0.593GlnHis: 0.593 ± 0.023	1.527GlnIle: 1.527 ± 0.048	0.998GlnLys: 0.998 ± 0.028	3.054GlnLeu: 3.054 ± 0.086	0.807GlnMet: 0.807 ± 0.029	0.674GlnAsn: 0.674 ± 0.02	1.943GlnPro: 1.943 ± 0.046	1.116GlnGln: 1.116 ± 0.036	2.386GlnArg: 2.386 ± 0.048	1.438GlnSer: 1.438 ± 0.036	1.749GlnThr: 1.749 ± 0.038	2.602GlnVal: 2.602 ± 0.053	0.368GlnTrp: 0.368 ± 0.019	0.535GlnTyr: 0.535 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	9.609ArgAla: 9.609 ± 0.104	0.503ArgCys: 0.503 ± 0.022	3.927ArgAsp: 3.927 ± 0.065	4.538ArgGlu: 4.538 ± 0.078	2.863ArgPhe: 2.863 ± 0.054	5.384ArgGly: 5.384 ± 0.078	1.51ArgHis: 1.51 ± 0.033	3.508ArgIle: 3.508 ± 0.055	2.16ArgLys: 2.16 ± 0.047	8.793ArgLeu: 8.793 ± 0.103	1.862ArgMet: 1.862 ± 0.041	1.516ArgAsn: 1.516 ± 0.038	4.401ArgPro: 4.401 ± 0.072	2.412ArgGln: 2.412 ± 0.049	6.666ArgArg: 6.666 ± 0.098	3.266ArgSer: 3.266 ± 0.053	3.577ArgThr: 3.577 ± 0.057	4.918ArgVal: 4.918 ± 0.065	1.223ArgTrp: 1.223 ± 0.035	1.793ArgTyr: 1.793 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	6.191SerAla: 6.191 ± 0.088	0.349SerCys: 0.349 ± 0.017	2.631SerAsp: 2.631 ± 0.046	2.524SerGlu: 2.524 ± 0.043	1.847SerPhe: 1.847 ± 0.041	5.188SerGly: 5.188 ± 0.078	1.006SerHis: 1.006 ± 0.03	1.934SerIle: 1.934 ± 0.046	1.389SerLys: 1.389 ± 0.039	4.98SerLeu: 4.98 ± 0.069	1.083SerMet: 1.083 ± 0.027	1.112SerAsn: 1.112 ± 0.033	2.989SerPro: 2.989 ± 0.053	1.558SerGln: 1.558 ± 0.044	3.281SerArg: 3.281 ± 0.053	2.318SerSer: 2.318 ± 0.054	2.341SerThr: 2.341 ± 0.06	3.38SerVal: 3.38 ± 0.047	0.713SerTrp: 0.713 ± 0.028	1.141SerTyr: 1.141 ± 0.034	0.0SerXaa: 0.0 ± 0.0
Thr	6.629ThrAla: 6.629 ± 0.096	0.38ThrCys: 0.38 ± 0.019	2.521ThrAsp: 2.521 ± 0.054	2.415ThrGlu: 2.415 ± 0.043	1.93ThrPhe: 1.93 ± 0.044	5.182ThrGly: 5.182 ± 0.083	0.978ThrHis: 0.978 ± 0.03	2.035ThrIle: 2.035 ± 0.045	1.245ThrLys: 1.245 ± 0.042	5.435ThrLeu: 5.435 ± 0.076	0.861ThrMet: 0.861 ± 0.027	1.143ThrAsn: 1.143 ± 0.039	3.764ThrPro: 3.764 ± 0.062	1.448ThrGln: 1.448 ± 0.115	3.167ThrArg: 3.167 ± 0.056	2.608ThrSer: 2.608 ± 0.062	2.746ThrThr: 2.746 ± 0.072	3.865ThrVal: 3.865 ± 0.072	0.713ThrTrp: 0.713 ± 0.027	1.289ThrTyr: 1.289 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	9.934ValAla: 9.934 ± 0.099	0.653ValCys: 0.653 ± 0.021	4.178ValAsp: 4.178 ± 0.057	4.797ValGlu: 4.797 ± 0.072	2.751ValPhe: 2.751 ± 0.05	6.083ValGly: 6.083 ± 0.078	1.314ValHis: 1.314 ± 0.035	3.562ValIle: 3.562 ± 0.061	2.429ValLys: 2.429 ± 0.05	7.409ValLeu: 7.409 ± 0.097	1.7ValMet: 1.7 ± 0.039	1.801ValAsn: 1.801 ± 0.035	3.125ValPro: 3.125 ± 0.053	2.204ValGln: 2.204 ± 0.048	5.638ValArg: 5.638 ± 0.079	4.063ValSer: 4.063 ± 0.067	4.429ValThr: 4.429 ± 0.07	6.337ValVal: 6.337 ± 0.082	1.063ValTrp: 1.063 ± 0.034	1.441ValTyr: 1.441 ± 0.035	0.0ValXaa: 0.0 ± 0.0
Trp	1.608TrpAla: 1.608 ± 0.04	0.133TrpCys: 0.133 ± 0.012	0.668TrpAsp: 0.668 ± 0.025	0.621TrpGlu: 0.621 ± 0.022	0.522TrpPhe: 0.522 ± 0.023	1.04TrpGly: 1.04 ± 0.029	0.251TrpHis: 0.251 ± 0.017	0.704TrpIle: 0.704 ± 0.027	0.497TrpLys: 0.497 ± 0.021	1.68TrpLeu: 1.68 ± 0.047	0.371TrpMet: 0.371 ± 0.018	0.43TrpAsn: 0.43 ± 0.016	0.766TrpPro: 0.766 ± 0.027	0.42TrpGln: 0.42 ± 0.019	1.536TrpArg: 1.536 ± 0.038	0.902TrpSer: 0.902 ± 0.028	0.949TrpThr: 0.949 ± 0.029	0.837TrpVal: 0.837 ± 0.024	0.241TrpTrp: 0.241 ± 0.015	0.288TrpTyr: 0.288 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.806TyrAla: 2.806 ± 0.051	0.205TyrCys: 0.205 ± 0.014	1.55TyrAsp: 1.55 ± 0.038	1.325TyrGlu: 1.325 ± 0.031	0.876TyrPhe: 0.876 ± 0.028	2.263TyrGly: 2.263 ± 0.054	0.404TyrHis: 0.404 ± 0.017	0.687TyrIle: 0.687 ± 0.023	0.577TyrLys: 0.577 ± 0.025	2.083TyrLeu: 2.083 ± 0.042	0.407TyrMet: 0.407 ± 0.02	0.569TyrAsn: 0.569 ± 0.023	1.031TyrPro: 1.031 ± 0.03	0.67TyrGln: 0.67 ± 0.029	1.783TyrArg: 1.783 ± 0.038	1.005TyrSer: 1.005 ± 0.03	0.956TyrThr: 0.956 ± 0.033	1.738TyrVal: 1.738 ± 0.044	0.368TyrTrp: 0.368 ± 0.018	0.565TyrTyr: 0.565 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3905 proteins (1208133 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---