Amino acid dipepetide frequency for Desulfuribacillus stibiiarsenatis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.014AlaAla: 5.014 ± 0.117	0.754AlaCys: 0.754 ± 0.032	3.401AlaAsp: 3.401 ± 0.062	4.295AlaGlu: 4.295 ± 0.073	2.801AlaPhe: 2.801 ± 0.061	4.768AlaGly: 4.768 ± 0.085	1.243AlaHis: 1.243 ± 0.039	6.487AlaIle: 6.487 ± 0.09	4.776AlaLys: 4.776 ± 0.084	6.576AlaLeu: 6.576 ± 0.086	1.978AlaMet: 1.978 ± 0.047	3.222AlaAsn: 3.222 ± 0.066	1.975AlaPro: 1.975 ± 0.058	2.372AlaGln: 2.372 ± 0.067	2.755AlaArg: 2.755 ± 0.056	3.932AlaSer: 3.932 ± 0.079	3.874AlaThr: 3.874 ± 0.078	4.976AlaVal: 4.976 ± 0.101	0.588AlaTrp: 0.588 ± 0.027	2.322AlaTyr: 2.322 ± 0.049	0.0AlaXaa: 0.0 ± 0.0
Cys	0.51CysAla: 0.51 ± 0.023	0.136CysCys: 0.136 ± 0.013	0.494CysAsp: 0.494 ± 0.024	0.529CysGlu: 0.529 ± 0.027	0.364CysPhe: 0.364 ± 0.02	0.839CysGly: 0.839 ± 0.037	0.311CysHis: 0.311 ± 0.027	0.788CysIle: 0.788 ± 0.036	0.612CysLys: 0.612 ± 0.026	0.795CysLeu: 0.795 ± 0.033	0.25CysMet: 0.25 ± 0.016	0.511CysAsn: 0.511 ± 0.027	0.509CysPro: 0.509 ± 0.029	0.335CysGln: 0.335 ± 0.023	0.342CysArg: 0.342 ± 0.022	0.632CysSer: 0.632 ± 0.029	0.488CysThr: 0.488 ± 0.027	0.598CysVal: 0.598 ± 0.027	0.088CysTrp: 0.088 ± 0.01	0.338CysTyr: 0.338 ± 0.019	0.0CysXaa: 0.0 ± 0.0
Asp	3.409AspAla: 3.409 ± 0.066	0.599AspCys: 0.599 ± 0.029	2.387AspAsp: 2.387 ± 0.067	3.859AspGlu: 3.859 ± 0.073	2.489AspPhe: 2.489 ± 0.054	3.164AspGly: 3.164 ± 0.071	1.004AspHis: 1.004 ± 0.036	5.064AspIle: 5.064 ± 0.084	3.34AspLys: 3.34 ± 0.055	4.855AspLeu: 4.855 ± 0.072	1.407AspMet: 1.407 ± 0.039	2.158AspAsn: 2.158 ± 0.057	1.794AspPro: 1.794 ± 0.045	2.016AspGln: 2.016 ± 0.048	2.326AspArg: 2.326 ± 0.058	2.905AspSer: 2.905 ± 0.066	2.724AspThr: 2.724 ± 0.055	3.817AspVal: 3.817 ± 0.064	0.614AspTrp: 0.614 ± 0.028	2.227AspTyr: 2.227 ± 0.052	0.0AspXaa: 0.0 ± 0.0
Glu	4.609GluAla: 4.609 ± 0.093	0.454GluCys: 0.454 ± 0.023	3.429GluAsp: 3.429 ± 0.064	5.468GluGlu: 5.468 ± 0.106	2.626GluPhe: 2.626 ± 0.056	3.797GluGly: 3.797 ± 0.077	1.543GluHis: 1.543 ± 0.041	6.41GluIle: 6.41 ± 0.101	5.515GluLys: 5.515 ± 0.091	6.936GluLeu: 6.936 ± 0.094	2.061GluMet: 2.061 ± 0.053	3.471GluAsn: 3.471 ± 0.065	1.756GluPro: 1.756 ± 0.05	3.582GluGln: 3.582 ± 0.064	3.319GluArg: 3.319 ± 0.063	3.515GluSer: 3.515 ± 0.066	3.326GluThr: 3.326 ± 0.061	4.985GluVal: 4.985 ± 0.072	0.652GluTrp: 0.652 ± 0.027	2.534GluTyr: 2.534 ± 0.053	0.0GluXaa: 0.0 ± 0.0
Phe	3.01PheAla: 3.01 ± 0.063	0.401PheCys: 0.401 ± 0.018	2.349PheAsp: 2.349 ± 0.052	2.593PheGlu: 2.593 ± 0.055	1.976PhePhe: 1.976 ± 0.061	2.826PheGly: 2.826 ± 0.06	0.956PheHis: 0.956 ± 0.041	3.6PheIle: 3.6 ± 0.072	2.14PheLys: 2.14 ± 0.051	4.121PheLeu: 4.121 ± 0.094	1.083PheMet: 1.083 ± 0.036	1.803PheAsn: 1.803 ± 0.049	1.442PhePro: 1.442 ± 0.046	1.811PheGln: 1.811 ± 0.044	1.518PheArg: 1.518 ± 0.039	2.863PheSer: 2.863 ± 0.057	2.516PheThr: 2.516 ± 0.06	3.004PheVal: 3.004 ± 0.061	0.399PheTrp: 0.399 ± 0.022	1.591PheTyr: 1.591 ± 0.045	0.0PheXaa: 0.0 ± 0.0
Gly	4.461GlyAla: 4.461 ± 0.084	0.884GlyCys: 0.884 ± 0.036	3.011GlyAsp: 3.011 ± 0.06	3.878GlyGlu: 3.878 ± 0.062	3.082GlyPhe: 3.082 ± 0.06	4.145GlyGly: 4.145 ± 0.091	1.366GlyHis: 1.366 ± 0.036	6.297GlyIle: 6.297 ± 0.093	4.729GlyLys: 4.729 ± 0.078	6.032GlyLeu: 6.032 ± 0.085	1.917GlyMet: 1.917 ± 0.049	2.888GlyAsn: 2.888 ± 0.067	1.571GlyPro: 1.571 ± 0.044	2.37GlyGln: 2.37 ± 0.054	2.575GlyArg: 2.575 ± 0.053	3.736GlySer: 3.736 ± 0.072	3.817GlyThr: 3.817 ± 0.073	4.822GlyVal: 4.822 ± 0.09	0.649GlyTrp: 0.649 ± 0.026	2.771GlyTyr: 2.771 ± 0.062	0.0GlyXaa: 0.0 ± 0.0
His	1.314HisAla: 1.314 ± 0.042	0.278HisCys: 0.278 ± 0.02	1.031HisAsp: 1.031 ± 0.04	1.354HisGlu: 1.354 ± 0.041	0.993HisPhe: 0.993 ± 0.031	1.45HisGly: 1.45 ± 0.046	0.621HisHis: 0.621 ± 0.029	1.795HisIle: 1.795 ± 0.047	1.283HisLys: 1.283 ± 0.036	1.904HisLeu: 1.904 ± 0.047	0.562HisMet: 0.562 ± 0.025	0.999HisAsn: 0.999 ± 0.034	1.034HisPro: 1.034 ± 0.032	0.926HisGln: 0.926 ± 0.032	0.955HisArg: 0.955 ± 0.032	1.335HisSer: 1.335 ± 0.037	1.086HisThr: 1.086 ± 0.038	1.461HisVal: 1.461 ± 0.035	0.267HisTrp: 0.267 ± 0.018	0.845HisTyr: 0.845 ± 0.031	0.0HisXaa: 0.0 ± 0.0
Ile	6.772IleAla: 6.772 ± 0.105	0.821IleCys: 0.821 ± 0.031	5.426IleAsp: 5.426 ± 0.069	6.466IleGlu: 6.466 ± 0.088	3.405IlePhe: 3.405 ± 0.059	6.049IleGly: 6.049 ± 0.095	1.928IleHis: 1.928 ± 0.049	7.148IleIle: 7.148 ± 0.111	4.78IleLys: 4.78 ± 0.081	7.811IleLeu: 7.811 ± 0.106	2.023IleMet: 2.023 ± 0.049	3.774IleAsn: 3.774 ± 0.062	3.565IlePro: 3.565 ± 0.071	3.682IleGln: 3.682 ± 0.073	3.759IleArg: 3.759 ± 0.064	5.642IleSer: 5.642 ± 0.096	4.981IleThr: 4.981 ± 0.09	6.256IleVal: 6.256 ± 0.087	0.621IleTrp: 0.621 ± 0.026	2.808IleTyr: 2.808 ± 0.063	0.0IleXaa: 0.0 ± 0.0
Lys	4.491LysAla: 4.491 ± 0.066	0.488LysCys: 0.488 ± 0.026	3.878LysAsp: 3.878 ± 0.069	5.719LysGlu: 5.719 ± 0.089	1.952LysPhe: 1.952 ± 0.049	4.082LysGly: 4.082 ± 0.076	1.453LysHis: 1.453 ± 0.036	5.36LysIle: 5.36 ± 0.074	5.129LysLys: 5.129 ± 0.093	5.798LysLeu: 5.798 ± 0.083	1.881LysMet: 1.881 ± 0.046	3.366LysAsn: 3.366 ± 0.053	2.243LysPro: 2.243 ± 0.056	3.032LysGln: 3.032 ± 0.064	2.956LysArg: 2.956 ± 0.072	3.531LysSer: 3.531 ± 0.065	3.368LysThr: 3.368 ± 0.057	4.658LysVal: 4.658 ± 0.077	0.565LysTrp: 0.565 ± 0.027	2.354LysTyr: 2.354 ± 0.051	0.0LysXaa: 0.0 ± 0.0
Leu	7.08LeuAla: 7.08 ± 0.093	0.818LeuCys: 0.818 ± 0.029	4.893LeuAsp: 4.893 ± 0.085	6.717LeuGlu: 6.717 ± 0.101	4.041LeuPhe: 4.041 ± 0.084	6.249LeuGly: 6.249 ± 0.103	2.064LeuHis: 2.064 ± 0.053	7.177LeuIle: 7.177 ± 0.113	6.093LeuLys: 6.093 ± 0.097	9.677LeuLeu: 9.677 ± 0.136	2.376LeuMet: 2.376 ± 0.052	4.154LeuAsn: 4.154 ± 0.061	3.778LeuPro: 3.778 ± 0.068	4.219LeuGln: 4.219 ± 0.078	3.981LeuArg: 3.981 ± 0.067	6.183LeuSer: 6.183 ± 0.08	5.165LeuThr: 5.165 ± 0.07	6.279LeuVal: 6.279 ± 0.08	0.733LeuTrp: 0.733 ± 0.031	3.004LeuTyr: 3.004 ± 0.063	0.0LeuXaa: 0.0 ± 0.0
Met	1.873MetAla: 1.873 ± 0.046	0.214MetCys: 0.214 ± 0.016	1.447MetAsp: 1.447 ± 0.036	1.821MetGlu: 1.821 ± 0.042	1.049MetPhe: 1.049 ± 0.036	1.824MetGly: 1.824 ± 0.05	0.471MetHis: 0.471 ± 0.022	2.306MetIle: 2.306 ± 0.053	2.2MetLys: 2.2 ± 0.054	2.615MetLeu: 2.615 ± 0.051	0.688MetMet: 0.688 ± 0.03	1.567MetAsn: 1.567 ± 0.043	0.971MetPro: 0.971 ± 0.031	1.014MetGln: 1.014 ± 0.031	1.123MetArg: 1.123 ± 0.037	1.618MetSer: 1.618 ± 0.045	1.5MetThr: 1.5 ± 0.045	1.821MetVal: 1.821 ± 0.05	0.16MetTrp: 0.16 ± 0.013	0.859MetTyr: 0.859 ± 0.031	0.0MetXaa: 0.0 ± 0.0
Asn	2.856AsnAla: 2.856 ± 0.07	0.422AsnCys: 0.422 ± 0.022	2.312AsnAsp: 2.312 ± 0.054	3.169AsnGlu: 3.169 ± 0.061	1.818AsnPhe: 1.818 ± 0.051	2.89AsnGly: 2.89 ± 0.067	1.296AsnHis: 1.296 ± 0.039	4.303AsnIle: 4.303 ± 0.07	2.969AsnLys: 2.969 ± 0.06	4.219AsnLeu: 4.219 ± 0.081	1.282AsnMet: 1.282 ± 0.035	2.269AsnAsn: 2.269 ± 0.065	2.159AsnPro: 2.159 ± 0.058	2.465AsnGln: 2.465 ± 0.051	2.337AsnArg: 2.337 ± 0.053	2.674AsnSer: 2.674 ± 0.056	2.36AsnThr: 2.36 ± 0.057	3.221AsnVal: 3.221 ± 0.069	0.438AsnTrp: 0.438 ± 0.02	1.707AsnTyr: 1.707 ± 0.043	0.0AsnXaa: 0.0 ± 0.0
Pro	2.128ProAla: 2.128 ± 0.062	0.299ProCys: 0.299 ± 0.018	1.894ProAsp: 1.894 ± 0.055	2.736ProGlu: 2.736 ± 0.058	1.655ProPhe: 1.655 ± 0.04	2.187ProGly: 2.187 ± 0.063	0.741ProHis: 0.741 ± 0.036	3.196ProIle: 3.196 ± 0.06	2.177ProLys: 2.177 ± 0.047	3.198ProLeu: 3.198 ± 0.061	0.99ProMet: 0.99 ± 0.031	1.758ProAsn: 1.758 ± 0.045	0.972ProPro: 0.972 ± 0.046	1.239ProGln: 1.239 ± 0.043	1.152ProArg: 1.152 ± 0.036	2.003ProSer: 2.003 ± 0.045	2.074ProThr: 2.074 ± 0.051	2.829ProVal: 2.829 ± 0.054	0.375ProTrp: 0.375 ± 0.021	1.375ProTyr: 1.375 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	3.024GlnAla: 3.024 ± 0.056	0.315GlnCys: 0.315 ± 0.02	1.918GlnAsp: 1.918 ± 0.05	3.287GlnGlu: 3.287 ± 0.063	1.528GlnPhe: 1.528 ± 0.043	2.357GlnGly: 2.357 ± 0.053	0.886GlnHis: 0.886 ± 0.036	3.184GlnIle: 3.184 ± 0.068	2.856GlnLys: 2.856 ± 0.066	4.255GlnLeu: 4.255 ± 0.076	1.184GlnMet: 1.184 ± 0.031	1.825GlnAsn: 1.825 ± 0.047	1.374GlnPro: 1.374 ± 0.043	2.248GlnGln: 2.248 ± 0.059	1.796GlnArg: 1.796 ± 0.046	2.416GlnSer: 2.416 ± 0.055	2.031GlnThr: 2.031 ± 0.044	2.846GlnVal: 2.846 ± 0.054	0.514GlnTrp: 0.514 ± 0.023	1.685GlnTyr: 1.685 ± 0.046	0.0GlnXaa: 0.0 ± 0.0
Arg	2.51ArgAla: 2.51 ± 0.052	0.353ArgCys: 0.353 ± 0.018	2.223ArgAsp: 2.223 ± 0.057	3.141ArgGlu: 3.141 ± 0.072	1.866ArgPhe: 1.866 ± 0.049	2.52ArgGly: 2.52 ± 0.051	0.775ArgHis: 0.775 ± 0.031	3.759ArgIle: 3.759 ± 0.067	3.27ArgLys: 3.27 ± 0.07	3.959ArgLeu: 3.959 ± 0.064	1.297ArgMet: 1.297 ± 0.039	2.202ArgAsn: 2.202 ± 0.053	1.372ArgPro: 1.372 ± 0.041	1.563ArgGln: 1.563 ± 0.039	1.784ArgArg: 1.784 ± 0.053	2.248ArgSer: 2.248 ± 0.047	2.139ArgThr: 2.139 ± 0.047	2.975ArgVal: 2.975 ± 0.061	0.41ArgTrp: 0.41 ± 0.021	1.598ArgTyr: 1.598 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	3.436SerAla: 3.436 ± 0.067	0.557SerCys: 0.557 ± 0.026	2.863SerAsp: 2.863 ± 0.064	3.732SerGlu: 3.732 ± 0.065	2.894SerPhe: 2.894 ± 0.055	4.037SerGly: 4.037 ± 0.068	1.301SerHis: 1.301 ± 0.043	5.581SerIle: 5.581 ± 0.083	3.913SerLys: 3.913 ± 0.065	5.857SerLeu: 5.857 ± 0.085	1.725SerMet: 1.725 ± 0.046	3.026SerAsn: 3.026 ± 0.067	1.929SerPro: 1.929 ± 0.051	2.223SerGln: 2.223 ± 0.059	2.297SerArg: 2.297 ± 0.054	3.784SerSer: 3.784 ± 0.082	3.172SerThr: 3.172 ± 0.06	4.144SerVal: 4.144 ± 0.071	0.591SerTrp: 0.591 ± 0.026	2.276SerTyr: 2.276 ± 0.05	0.0SerXaa: 0.0 ± 0.0
Thr	3.677ThrAla: 3.677 ± 0.058	0.538ThrCys: 0.538 ± 0.024	2.744ThrAsp: 2.744 ± 0.061	3.431ThrGlu: 3.431 ± 0.074	2.364ThrPhe: 2.364 ± 0.051	4.177ThrGly: 4.177 ± 0.08	1.104ThrHis: 1.104 ± 0.034	5.15ThrIle: 5.15 ± 0.099	3.347ThrLys: 3.347 ± 0.069	5.021ThrLeu: 5.021 ± 0.081	1.395ThrMet: 1.395 ± 0.039	2.638ThrAsn: 2.638 ± 0.052	2.245ThrPro: 2.245 ± 0.049	1.753ThrGln: 1.753 ± 0.043	2.007ThrArg: 2.007 ± 0.047	3.117ThrSer: 3.117 ± 0.066	3.159ThrThr: 3.159 ± 0.074	4.098ThrVal: 4.098 ± 0.083	0.485ThrTrp: 0.485 ± 0.025	1.869ThrTyr: 1.869 ± 0.058	0.0ThrXaa: 0.0 ± 0.0
Val	5.325ValAla: 5.325 ± 0.089	0.664ValCys: 0.664 ± 0.026	3.839ValAsp: 3.839 ± 0.068	4.859ValGlu: 4.859 ± 0.082	3.056ValPhe: 3.056 ± 0.061	4.624ValGly: 4.624 ± 0.078	1.281ValHis: 1.281 ± 0.037	6.319ValIle: 6.319 ± 0.094	4.392ValLys: 4.392 ± 0.069	6.656ValLeu: 6.656 ± 0.095	1.903ValMet: 1.903 ± 0.05	3.249ValAsn: 3.249 ± 0.06	2.56ValPro: 2.56 ± 0.055	2.479ValGln: 2.479 ± 0.059	2.839ValArg: 2.839 ± 0.061	4.472ValSer: 4.472 ± 0.075	4.222ValThr: 4.222 ± 0.092	5.294ValVal: 5.294 ± 0.096	0.563ValTrp: 0.563 ± 0.027	2.372ValTyr: 2.372 ± 0.048	0.0ValXaa: 0.0 ± 0.0
Trp	0.519TrpAla: 0.519 ± 0.024	0.084TrpCys: 0.084 ± 0.011	0.513TrpAsp: 0.513 ± 0.025	0.64TrpGlu: 0.64 ± 0.028	0.388TrpPhe: 0.388 ± 0.022	0.595TrpGly: 0.595 ± 0.027	0.217TrpHis: 0.217 ± 0.016	0.763TrpIle: 0.763 ± 0.031	0.639TrpLys: 0.639 ± 0.026	0.93TrpLeu: 0.93 ± 0.035	0.284TrpMet: 0.284 ± 0.016	0.557TrpAsn: 0.557 ± 0.024	0.245TrpPro: 0.245 ± 0.018	0.438TrpGln: 0.438 ± 0.023	0.39TrpArg: 0.39 ± 0.02	0.535TrpSer: 0.535 ± 0.024	0.429TrpThr: 0.429 ± 0.021	0.59TrpVal: 0.59 ± 0.025	0.134TrpTrp: 0.134 ± 0.012	0.344TrpTyr: 0.344 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.093TyrAla: 2.093 ± 0.055	0.389TyrCys: 0.389 ± 0.021	2.106TyrAsp: 2.106 ± 0.066	2.294TyrGlu: 2.294 ± 0.053	1.654TyrPhe: 1.654 ± 0.044	2.422TyrGly: 2.422 ± 0.054	0.931TyrHis: 0.931 ± 0.035	3.031TyrIle: 3.031 ± 0.053	2.142TyrLys: 2.142 ± 0.052	3.466TyrLeu: 3.466 ± 0.068	0.853TyrMet: 0.853 ± 0.031	1.73TyrAsn: 1.73 ± 0.05	1.484TyrPro: 1.484 ± 0.045	1.764TyrGln: 1.764 ± 0.048	1.754TyrArg: 1.754 ± 0.05	2.197TyrSer: 2.197 ± 0.054	1.887TyrThr: 1.887 ± 0.048	2.296TyrVal: 2.296 ± 0.058	0.388TyrTrp: 0.388 ± 0.02	1.564TyrTyr: 1.564 ± 0.047	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2918 proteins (900260 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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