Amino acid dipepetide frequency for Red clover powdery mildew-associated totivirus 5

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.041AlaAla: 3.041 ± 1.289
1.217AlaCys: 1.217 ± 0.836
3.041AlaAsp: 3.041 ± 0.4
5.474AlaGlu: 5.474 ± 0.462
2.433AlaPhe: 2.433 ± 1.672
4.866AlaGly: 4.866 ± 0.88
0.0AlaHis: 0.0 ± 0.0
5.474AlaIle: 5.474 ± 0.383
4.866AlaLys: 4.866 ± 0.035
7.908AlaLeu: 7.908 ± 3.013
1.825AlaMet: 1.825 ± 0.409
5.474AlaAsn: 5.474 ± 0.383
1.217AlaPro: 1.217 ± 0.836
2.433AlaGln: 2.433 ± 0.017
4.258AlaArg: 4.258 ± 0.453
3.041AlaSer: 3.041 ± 0.444
1.217AlaThr: 1.217 ± 0.836
6.083AlaVal: 6.083 ± 0.801
1.217AlaTrp: 1.217 ± 0.009
1.217AlaTyr: 1.217 ± 0.009
0.0AlaXaa: 0.0 ± 0.0
Cys
0.608CysAla: 0.608 ± 0.427
0.608CysCys: 0.608 ± 0.427
1.217CysAsp: 1.217 ± 0.853
0.608CysGlu: 0.608 ± 0.418
3.041CysPhe: 3.041 ± 1.245
0.0CysGly: 0.0 ± 0.0
0.608CysHis: 0.608 ± 0.427
0.608CysIle: 0.608 ± 0.427
1.825CysLys: 1.825 ± 0.409
1.217CysLeu: 1.217 ± 0.009
0.0CysMet: 0.0 ± 0.0
0.608CysAsn: 0.608 ± 0.418
0.608CysPro: 0.608 ± 0.427
0.0CysGln: 0.0 ± 0.0
1.217CysArg: 1.217 ± 0.836
2.433CysSer: 2.433 ± 0.827
0.608CysThr: 0.608 ± 0.427
0.0CysVal: 0.0 ± 0.0
0.608CysTrp: 0.608 ± 0.427
1.217CysTyr: 1.217 ± 0.009
0.0CysXaa: 0.0 ± 0.0
Asp
0.608AspAla: 0.608 ± 0.427
0.608AspCys: 0.608 ± 0.418
3.65AspAsp: 3.65 ± 0.026
3.65AspGlu: 3.65 ± 0.871
4.866AspPhe: 4.866 ± 0.81
4.258AspGly: 4.258 ± 2.142
1.825AspHis: 1.825 ± 0.409
5.474AspIle: 5.474 ± 1.228
4.258AspLys: 4.258 ± 0.392
5.474AspLeu: 5.474 ± 1.228
1.217AspMet: 1.217 ± 0.853
2.433AspAsn: 2.433 ± 0.017
1.825AspPro: 1.825 ± 0.435
0.608AspGln: 0.608 ± 0.427
1.825AspArg: 1.825 ± 1.28
4.258AspSer: 4.258 ± 0.453
0.608AspThr: 0.608 ± 0.427
4.866AspVal: 4.866 ± 0.88
0.608AspTrp: 0.608 ± 0.418
4.258AspTyr: 4.258 ± 0.453
0.0AspXaa: 0.0 ± 0.0
Glu
4.866GluAla: 4.866 ± 0.81
1.825GluCys: 1.825 ± 0.435
6.691GluAsp: 6.691 ± 2.063
1.217GluGlu: 1.217 ± 0.009
1.825GluPhe: 1.825 ± 0.409
2.433GluGly: 2.433 ± 0.017
0.608GluHis: 0.608 ± 0.418
3.041GluIle: 3.041 ± 0.4
1.825GluLys: 1.825 ± 0.409
5.474GluLeu: 5.474 ± 0.462
0.608GluMet: 0.608 ± 0.418
1.825GluAsn: 1.825 ± 1.28
0.608GluPro: 0.608 ± 0.418
3.65GluGln: 3.65 ± 0.026
4.866GluArg: 4.866 ± 0.88
5.474GluSer: 5.474 ± 1.306
2.433GluThr: 2.433 ± 0.862
4.258GluVal: 4.258 ± 2.081
1.217GluTrp: 1.217 ± 0.836
3.65GluTyr: 3.65 ± 1.715
0.0GluXaa: 0.0 ± 0.0
Phe
1.825PheAla: 1.825 ± 0.409
0.608PheCys: 0.608 ± 0.418
1.825PheAsp: 1.825 ± 0.435
3.65PheGlu: 3.65 ± 0.818
1.825PhePhe: 1.825 ± 1.254
7.299PheGly: 7.299 ± 2.586
0.608PheHis: 0.608 ± 0.427
2.433PheIle: 2.433 ± 1.672
2.433PheLys: 2.433 ± 0.017
5.474PheLeu: 5.474 ± 1.228
0.608PheMet: 0.608 ± 0.308
4.866PheAsn: 4.866 ± 0.035
3.041PhePro: 3.041 ± 1.245
0.608PheGln: 0.608 ± 0.418
3.041PheArg: 3.041 ± 1.245
4.258PheSer: 4.258 ± 1.236
2.433PheThr: 2.433 ± 0.827
1.217PheVal: 1.217 ± 0.009
1.217PheTrp: 1.217 ± 0.009
2.433PheTyr: 2.433 ± 0.862
0.0PheXaa: 0.0 ± 0.0
Gly
3.041GlyAla: 3.041 ± 1.245
0.608GlyCys: 0.608 ± 0.418
3.65GlyAsp: 3.65 ± 0.818
1.825GlyGlu: 1.825 ± 0.435
1.825GlyPhe: 1.825 ± 1.28
3.65GlyGly: 3.65 ± 0.026
0.608GlyHis: 0.608 ± 0.427
2.433GlyIle: 2.433 ± 0.862
2.433GlyLys: 2.433 ± 0.827
9.124GlyLeu: 9.124 ± 2.177
3.65GlyMet: 3.65 ± 1.715
1.217GlyAsn: 1.217 ± 0.009
1.825GlyPro: 1.825 ± 1.254
1.217GlyGln: 1.217 ± 0.009
4.258GlyArg: 4.258 ± 0.453
6.083GlySer: 6.083 ± 0.888
3.041GlyThr: 3.041 ± 1.289
6.691GlyVal: 6.691 ± 0.374
0.0GlyTrp: 0.0 ± 0.0
1.217GlyTyr: 1.217 ± 0.853
0.0GlyXaa: 0.0 ± 0.0
His
1.217HisAla: 1.217 ± 0.836
0.608HisCys: 0.608 ± 0.418
1.825HisAsp: 1.825 ± 1.28
0.608HisGlu: 0.608 ± 0.418
0.608HisPhe: 0.608 ± 0.427
0.608HisGly: 0.608 ± 0.418
1.217HisHis: 1.217 ± 0.009
1.217HisIle: 1.217 ± 0.009
1.217HisLys: 1.217 ± 0.009
2.433HisLeu: 2.433 ± 0.827
1.825HisMet: 1.825 ± 0.409
1.825HisAsn: 1.825 ± 0.435
0.0HisPro: 0.0 ± 0.0
0.608HisGln: 0.608 ± 0.418
0.608HisArg: 0.608 ± 0.427
3.65HisSer: 3.65 ± 0.026
1.217HisThr: 1.217 ± 0.009
0.608HisVal: 0.608 ± 0.427
0.608HisTrp: 0.608 ± 0.427
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
5.474IleAla: 5.474 ± 0.462
0.0IleCys: 0.0 ± 0.0
4.258IleAsp: 4.258 ± 1.236
2.433IleGlu: 2.433 ± 0.827
0.608IlePhe: 0.608 ± 0.427
2.433IleGly: 2.433 ± 0.017
0.0IleHis: 0.0 ± 0.0
4.866IleIle: 4.866 ± 0.81
4.258IleLys: 4.258 ± 1.236
5.474IleLeu: 5.474 ± 2.072
1.217IleMet: 1.217 ± 0.009
1.825IleAsn: 1.825 ± 0.435
1.825IlePro: 1.825 ± 0.409
2.433IleGln: 2.433 ± 0.862
2.433IleArg: 2.433 ± 0.017
6.083IleSer: 6.083 ± 0.888
4.258IleThr: 4.258 ± 1.236
3.041IleVal: 3.041 ± 0.444
0.0IleTrp: 0.0 ± 0.0
3.041IleTyr: 3.041 ± 0.444
0.0IleXaa: 0.0 ± 0.0
Lys
3.65LysAla: 3.65 ± 2.508
1.825LysCys: 1.825 ± 0.435
4.866LysAsp: 4.866 ± 1.654
1.217LysGlu: 1.217 ± 0.009
3.65LysPhe: 3.65 ± 1.715
1.217LysGly: 1.217 ± 0.009
0.608LysHis: 0.608 ± 0.418
1.825LysIle: 1.825 ± 0.409
2.433LysLys: 2.433 ± 0.017
4.866LysLeu: 4.866 ± 0.88
4.258LysMet: 4.258 ± 1.236
0.608LysAsn: 0.608 ± 0.427
1.825LysPro: 1.825 ± 0.409
1.825LysGln: 1.825 ± 0.435
3.65LysArg: 3.65 ± 0.818
4.866LysSer: 4.866 ± 0.81
3.041LysThr: 3.041 ± 0.4
6.691LysVal: 6.691 ± 2.063
0.608LysTrp: 0.608 ± 0.427
4.866LysTyr: 4.866 ± 1.724
0.0LysXaa: 0.0 ± 0.0
Leu
10.949LeuAla: 10.949 ± 2.612
4.258LeuCys: 4.258 ± 0.392
3.65LeuAsp: 3.65 ± 0.871
6.083LeuGlu: 6.083 ± 0.888
6.691LeuPhe: 6.691 ± 0.374
4.866LeuGly: 4.866 ± 1.724
2.433LeuHis: 2.433 ± 0.017
3.65LeuIle: 3.65 ± 1.715
3.041LeuLys: 3.041 ± 0.444
6.083LeuLeu: 6.083 ± 1.733
0.608LeuMet: 0.608 ± 0.418
4.258LeuAsn: 4.258 ± 0.453
4.258LeuPro: 4.258 ± 0.392
1.217LeuGln: 1.217 ± 0.009
5.474LeuArg: 5.474 ± 1.228
12.165LeuSer: 12.165 ± 0.087
6.691LeuThr: 6.691 ± 0.47
6.083LeuVal: 6.083 ± 1.645
1.825LeuTrp: 1.825 ± 0.409
0.0LeuTyr: 0.0 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
1.825MetAla: 1.825 ± 1.254
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.825MetGlu: 1.825 ± 0.409
1.217MetPhe: 1.217 ± 0.009
3.041MetGly: 3.041 ± 0.4
1.825MetHis: 1.825 ± 0.409
0.608MetIle: 0.608 ± 0.427
0.0MetLys: 0.0 ± 0.0
2.433MetLeu: 2.433 ± 1.707
0.0MetMet: 0.0 ± 0.0
1.825MetAsn: 1.825 ± 0.435
1.825MetPro: 1.825 ± 0.409
0.608MetGln: 0.608 ± 0.418
1.217MetArg: 1.217 ± 0.009
2.433MetSer: 2.433 ± 0.017
3.041MetThr: 3.041 ± 0.444
1.825MetVal: 1.825 ± 0.435
0.0MetTrp: 0.0 ± 0.0
1.217MetTyr: 1.217 ± 0.009
0.0MetXaa: 0.0 ± 0.0
Asn
0.608AsnAla: 0.608 ± 0.418
0.608AsnCys: 0.608 ± 0.427
3.041AsnAsp: 3.041 ± 2.133
4.258AsnGlu: 4.258 ± 0.392
0.608AsnPhe: 0.608 ± 0.418
2.433AsnGly: 2.433 ± 0.017
1.825AsnHis: 1.825 ± 0.435
1.825AsnIle: 1.825 ± 0.435
3.041AsnLys: 3.041 ± 0.4
4.258AsnLeu: 4.258 ± 0.392
1.217AsnMet: 1.217 ± 0.853
1.217AsnAsn: 1.217 ± 0.009
1.217AsnPro: 1.217 ± 0.853
0.608AsnGln: 0.608 ± 0.427
5.474AsnArg: 5.474 ± 1.228
4.258AsnSer: 4.258 ± 0.453
3.041AsnThr: 3.041 ± 0.444
4.866AsnVal: 4.866 ± 2.569
1.825AsnTrp: 1.825 ± 0.409
2.433AsnTyr: 2.433 ± 0.862
0.0AsnXaa: 0.0 ± 0.0
Pro
1.825ProAla: 1.825 ± 1.28
0.608ProCys: 0.608 ± 0.418
1.217ProAsp: 1.217 ± 0.009
3.65ProGlu: 3.65 ± 0.818
3.041ProPhe: 3.041 ± 1.245
1.217ProGly: 1.217 ± 0.836
0.0ProHis: 0.0 ± 0.0
3.041ProIle: 3.041 ± 1.245
3.65ProLys: 3.65 ± 0.026
0.608ProLeu: 0.608 ± 0.427
0.0ProMet: 0.0 ± 0.0
1.825ProAsn: 1.825 ± 0.409
1.825ProPro: 1.825 ± 0.435
0.608ProGln: 0.608 ± 0.427
0.0ProArg: 0.0 ± 0.0
2.433ProSer: 2.433 ± 0.017
3.65ProThr: 3.65 ± 1.663
2.433ProVal: 2.433 ± 0.862
0.0ProTrp: 0.0 ± 0.0
1.825ProTyr: 1.825 ± 0.409
0.0ProXaa: 0.0 ± 0.0
Gln
1.217GlnAla: 1.217 ± 0.009
0.0GlnCys: 0.0 ± 0.0
1.217GlnAsp: 1.217 ± 0.009
3.041GlnGlu: 3.041 ± 0.444
1.217GlnPhe: 1.217 ± 0.009
0.608GlnGly: 0.608 ± 0.427
1.825GlnHis: 1.825 ± 0.409
2.433GlnIle: 2.433 ± 0.827
0.608GlnLys: 0.608 ± 0.418
1.217GlnLeu: 1.217 ± 0.836
0.608GlnMet: 0.608 ± 0.427
1.217GlnAsn: 1.217 ± 0.009
1.217GlnPro: 1.217 ± 0.009
1.217GlnGln: 1.217 ± 0.836
0.0GlnArg: 0.0 ± 0.0
0.608GlnSer: 0.608 ± 0.427
1.825GlnThr: 1.825 ± 1.28
1.825GlnVal: 1.825 ± 0.409
0.608GlnTrp: 0.608 ± 0.427
2.433GlnTyr: 2.433 ± 1.672
0.0GlnXaa: 0.0 ± 0.0
Arg
6.083ArgAla: 6.083 ± 0.801
0.0ArgCys: 0.0 ± 0.0
1.825ArgAsp: 1.825 ± 1.28
4.258ArgGlu: 4.258 ± 0.453
4.866ArgPhe: 4.866 ± 0.81
6.083ArgGly: 6.083 ± 1.645
2.433ArgHis: 2.433 ± 0.827
1.217ArgIle: 1.217 ± 0.836
2.433ArgLys: 2.433 ± 0.827
6.691ArgLeu: 6.691 ± 1.315
2.433ArgMet: 2.433 ± 0.017
0.608ArgAsn: 0.608 ± 0.418
3.041ArgPro: 3.041 ± 0.4
0.608ArgGln: 0.608 ± 0.427
1.825ArgArg: 1.825 ± 0.409
5.474ArgSer: 5.474 ± 0.462
3.041ArgThr: 3.041 ± 0.4
1.217ArgVal: 1.217 ± 0.009
0.608ArgTrp: 0.608 ± 0.418
1.825ArgTyr: 1.825 ± 0.409
0.0ArgXaa: 0.0 ± 0.0
Ser
4.258SerAla: 4.258 ± 1.297
2.433SerCys: 2.433 ± 0.862
4.866SerAsp: 4.866 ± 2.569
4.866SerGlu: 4.866 ± 0.035
3.65SerPhe: 3.65 ± 0.818
5.474SerGly: 5.474 ± 0.462
1.217SerHis: 1.217 ± 0.009
5.474SerIle: 5.474 ± 0.462
7.299SerLys: 7.299 ± 0.792
6.083SerLeu: 6.083 ± 0.044
3.65SerMet: 3.65 ± 1.056
3.041SerAsn: 3.041 ± 0.444
0.608SerPro: 0.608 ± 0.427
2.433SerGln: 2.433 ± 0.827
6.691SerArg: 6.691 ± 2.063
6.691SerSer: 6.691 ± 1.219
8.516SerThr: 8.516 ± 0.061
4.866SerVal: 4.866 ± 0.035
1.217SerTrp: 1.217 ± 0.009
4.258SerTyr: 4.258 ± 0.392
0.0SerXaa: 0.0 ± 0.0
Thr
5.474ThrAla: 5.474 ± 0.383
0.0ThrCys: 0.0 ± 0.0
2.433ThrAsp: 2.433 ± 0.827
3.65ThrGlu: 3.65 ± 0.026
2.433ThrPhe: 2.433 ± 1.672
3.041ThrGly: 3.041 ± 1.289
1.217ThrHis: 1.217 ± 0.836
4.866ThrIle: 4.866 ± 0.88
4.258ThrLys: 4.258 ± 0.453
6.083ThrLeu: 6.083 ± 0.044
1.825ThrMet: 1.825 ± 0.409
3.041ThrAsn: 3.041 ± 0.444
3.041ThrPro: 3.041 ± 0.444
1.217ThrGln: 1.217 ± 0.009
3.65ThrArg: 3.65 ± 0.026
2.433ThrSer: 2.433 ± 0.827
4.866ThrThr: 4.866 ± 1.724
5.474ThrVal: 5.474 ± 1.306
0.0ThrTrp: 0.0 ± 0.0
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
2.433ValAla: 2.433 ± 0.017
1.825ValCys: 1.825 ± 0.435
3.65ValAsp: 3.65 ± 0.026
3.65ValGlu: 3.65 ± 0.026
3.65ValPhe: 3.65 ± 0.026
1.825ValGly: 1.825 ± 0.409
2.433ValHis: 2.433 ± 0.862
2.433ValIle: 2.433 ± 0.017
6.083ValLys: 6.083 ± 0.044
6.691ValLeu: 6.691 ± 1.219
0.608ValMet: 0.608 ± 0.427
5.474ValAsn: 5.474 ± 0.462
3.65ValPro: 3.65 ± 0.818
1.217ValGln: 1.217 ± 0.836
4.258ValArg: 4.258 ± 0.453
8.516ValSer: 8.516 ± 0.061
2.433ValThr: 2.433 ± 0.827
5.474ValVal: 5.474 ± 0.462
1.217ValTrp: 1.217 ± 0.009
1.825ValTyr: 1.825 ± 0.409
0.0ValXaa: 0.0 ± 0.0
Trp
3.041TrpAla: 3.041 ± 0.444
0.0TrpCys: 0.0 ± 0.0
0.608TrpAsp: 0.608 ± 0.418
1.217TrpGlu: 1.217 ± 0.836
2.433TrpPhe: 2.433 ± 0.862
0.0TrpGly: 0.0 ± 0.0
0.608TrpHis: 0.608 ± 0.427
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.608TrpLeu: 0.608 ± 0.427
0.0TrpMet: 0.0 ± 0.0
1.217TrpAsn: 1.217 ± 0.853
0.0TrpPro: 0.0 ± 0.0
0.608TrpGln: 0.608 ± 0.418
0.0TrpArg: 0.0 ± 0.0
1.825TrpSer: 1.825 ± 0.409
1.217TrpThr: 1.217 ± 0.836
0.608TrpVal: 0.608 ± 0.418
0.608TrpTrp: 0.608 ± 0.427
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.258TyrAla: 4.258 ± 0.453
0.0TyrCys: 0.0 ± 0.0
3.65TyrAsp: 3.65 ± 1.715
1.217TyrGlu: 1.217 ± 0.009
1.825TyrPhe: 1.825 ± 0.409
3.041TyrGly: 3.041 ± 0.4
0.608TyrHis: 0.608 ± 0.427
3.041TyrIle: 3.041 ± 1.245
2.433TyrLys: 2.433 ± 0.017
6.083TyrLeu: 6.083 ± 1.733
0.0TyrMet: 0.0 ± 0.0
4.258TyrAsn: 4.258 ± 2.142
0.0TyrPro: 0.0 ± 0.0
1.217TyrGln: 1.217 ± 0.836
1.825TyrArg: 1.825 ± 0.409
0.608TyrSer: 0.608 ± 0.418
1.825TyrThr: 1.825 ± 1.28
1.217TyrVal: 1.217 ± 0.836
0.608TyrTrp: 0.608 ± 0.427
0.608TyrTyr: 0.608 ± 0.427
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1645 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski