Amino acid dipepetide frequency for Hubei dimarhabdovirus virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.679AlaAla: 1.679 ± 0.518
0.56AlaCys: 0.56 ± 0.874
1.959AlaAsp: 1.959 ± 0.633
0.84AlaGlu: 0.84 ± 0.414
2.799AlaPhe: 2.799 ± 1.18
2.519AlaGly: 2.519 ± 0.572
1.12AlaHis: 1.12 ± 0.344
2.519AlaIle: 2.519 ± 0.273
2.799AlaLys: 2.799 ± 1.397
3.079AlaLeu: 3.079 ± 1.048
0.28AlaMet: 0.28 ± 0.495
1.399AlaAsn: 1.399 ± 0.62
0.56AlaPro: 0.56 ± 0.635
1.12AlaGln: 1.12 ± 0.535
0.56AlaArg: 0.56 ± 0.387
3.359AlaSer: 3.359 ± 1.966
2.239AlaThr: 2.239 ± 0.864
1.399AlaVal: 1.399 ± 0.921
0.0AlaTrp: 0.0 ± 0.0
2.239AlaTyr: 2.239 ± 0.873
0.0AlaXaa: 0.0 ± 0.0
Cys
0.84CysAla: 0.84 ± 0.796
0.0CysCys: 0.0 ± 0.0
1.12CysAsp: 1.12 ± 0.507
0.56CysGlu: 0.56 ± 0.339
0.28CysPhe: 0.28 ± 0.161
1.399CysGly: 1.399 ± 1.1
0.56CysHis: 0.56 ± 0.874
1.399CysIle: 1.399 ± 0.444
2.239CysLys: 2.239 ± 0.997
1.679CysLeu: 1.679 ± 0.965
0.0CysMet: 0.0 ± 0.0
0.84CysAsn: 0.84 ± 0.301
0.84CysPro: 0.84 ± 0.765
0.0CysGln: 0.0 ± 0.0
0.84CysArg: 0.84 ± 0.47
1.399CysSer: 1.399 ± 0.62
0.28CysThr: 0.28 ± 0.424
0.56CysVal: 0.56 ± 0.322
0.0CysTrp: 0.0 ± 0.0
1.12CysTyr: 1.12 ± 0.678
0.0CysXaa: 0.0 ± 0.0
Asp
2.239AspAla: 2.239 ± 0.926
1.12AspCys: 1.12 ± 0.609
3.079AspAsp: 3.079 ± 0.645
3.359AspGlu: 3.359 ± 0.963
2.519AspPhe: 2.519 ± 0.449
2.239AspGly: 2.239 ± 0.594
1.959AspHis: 1.959 ± 0.512
3.079AspIle: 3.079 ± 1.258
4.198AspLys: 4.198 ± 1.128
5.038AspLeu: 5.038 ± 0.937
1.679AspMet: 1.679 ± 0.753
3.638AspAsn: 3.638 ± 1.1
3.638AspPro: 3.638 ± 0.965
1.959AspGln: 1.959 ± 1.393
3.079AspArg: 3.079 ± 0.771
6.157AspSer: 6.157 ± 0.457
3.079AspThr: 3.079 ± 1.388
3.638AspVal: 3.638 ± 1.722
2.239AspTrp: 2.239 ± 0.648
2.799AspTyr: 2.799 ± 1.095
0.0AspXaa: 0.0 ± 0.0
Glu
1.12GluAla: 1.12 ± 0.99
0.56GluCys: 0.56 ± 0.874
3.079GluAsp: 3.079 ± 1.211
4.478GluGlu: 4.478 ± 1.204
2.799GluPhe: 2.799 ± 1.048
3.079GluGly: 3.079 ± 1.108
0.0GluHis: 0.0 ± 0.0
4.478GluIle: 4.478 ± 0.438
3.638GluLys: 3.638 ± 1.035
5.318GluLeu: 5.318 ± 1.119
1.959GluMet: 1.959 ± 0.901
2.239GluAsn: 2.239 ± 1.027
1.399GluPro: 1.399 ± 0.525
1.12GluGln: 1.12 ± 0.643
2.519GluArg: 2.519 ± 1.097
7.837GluSer: 7.837 ± 0.79
4.758GluThr: 4.758 ± 1.289
3.079GluVal: 3.079 ± 0.877
1.12GluTrp: 1.12 ± 0.774
1.679GluTyr: 1.679 ± 0.573
0.0GluXaa: 0.0 ± 0.0
Phe
0.28PheAla: 0.28 ± 0.161
0.0PheCys: 0.0 ± 0.0
2.239PheAsp: 2.239 ± 1.007
1.679PheGlu: 1.679 ± 0.366
1.399PhePhe: 1.399 ± 0.857
1.959PheGly: 1.959 ± 0.44
1.959PheHis: 1.959 ± 0.618
3.079PheIle: 3.079 ± 0.635
4.478PheLys: 4.478 ± 0.432
4.478PheLeu: 4.478 ± 0.845
1.12PheMet: 1.12 ± 0.292
1.959PheAsn: 1.959 ± 0.5
2.239PhePro: 2.239 ± 1.021
1.399PheGln: 1.399 ± 0.785
1.679PheArg: 1.679 ± 0.739
3.079PheSer: 3.079 ± 0.697
1.399PheThr: 1.399 ± 1.028
3.918PheVal: 3.918 ± 0.715
0.28PheTrp: 0.28 ± 0.161
1.12PheTyr: 1.12 ± 0.353
0.0PheXaa: 0.0 ± 0.0
Gly
1.399GlyAla: 1.399 ± 0.472
1.399GlyCys: 1.399 ± 0.902
3.079GlyAsp: 3.079 ± 1.2
3.079GlyGlu: 3.079 ± 1.804
2.519GlyPhe: 2.519 ± 1.289
2.519GlyGly: 2.519 ± 0.273
1.399GlyHis: 1.399 ± 0.62
3.638GlyIle: 3.638 ± 1.316
2.799GlyLys: 2.799 ± 0.97
4.758GlyLeu: 4.758 ± 1.743
1.399GlyMet: 1.399 ± 1.264
3.359GlyAsn: 3.359 ± 0.583
1.959GlyPro: 1.959 ± 1.085
1.959GlyGln: 1.959 ± 1.126
1.679GlyArg: 1.679 ± 0.828
5.038GlySer: 5.038 ± 0.637
1.679GlyThr: 1.679 ± 1.161
3.638GlyVal: 3.638 ± 1.022
0.84GlyTrp: 0.84 ± 0.301
2.799GlyTyr: 2.799 ± 0.889
0.0GlyXaa: 0.0 ± 0.0
His
0.84HisAla: 0.84 ± 0.556
0.28HisCys: 0.28 ± 0.161
1.399HisAsp: 1.399 ± 0.472
0.56HisGlu: 0.56 ± 0.322
1.679HisPhe: 1.679 ± 0.573
0.56HisGly: 0.56 ± 0.339
0.56HisHis: 0.56 ± 0.874
2.239HisIle: 2.239 ± 0.692
1.679HisLys: 1.679 ± 0.573
3.359HisLeu: 3.359 ± 1.031
0.0HisMet: 0.0 ± 0.0
1.399HisAsn: 1.399 ± 0.444
1.679HisPro: 1.679 ± 0.345
0.84HisGln: 0.84 ± 0.301
0.84HisArg: 0.84 ± 0.483
2.239HisSer: 2.239 ± 0.864
1.12HisThr: 1.12 ± 0.631
1.399HisVal: 1.399 ± 0.476
0.56HisTrp: 0.56 ± 0.322
1.12HisTyr: 1.12 ± 0.768
0.0HisXaa: 0.0 ± 0.0
Ile
2.519IleAla: 2.519 ± 1.631
1.959IleCys: 1.959 ± 0.618
5.877IleAsp: 5.877 ± 1.316
4.478IleGlu: 4.478 ± 0.927
3.918IlePhe: 3.918 ± 1.273
4.758IleGly: 4.758 ± 1.129
1.679IleHis: 1.679 ± 0.828
6.157IleIle: 6.157 ± 1.725
7.277IleLys: 7.277 ± 1.697
5.877IleLeu: 5.877 ± 1.026
1.399IleMet: 1.399 ± 0.891
6.157IleAsn: 6.157 ± 1.745
5.877IlePro: 5.877 ± 2.111
3.638IleGln: 3.638 ± 0.261
5.318IleArg: 5.318 ± 1.027
5.318IleSer: 5.318 ± 0.866
4.758IleThr: 4.758 ± 0.546
4.198IleVal: 4.198 ± 1.575
1.399IleTrp: 1.399 ± 0.31
4.758IleTyr: 4.758 ± 0.957
0.0IleXaa: 0.0 ± 0.0
Lys
1.679LysAla: 1.679 ± 0.658
0.84LysCys: 0.84 ± 0.483
4.198LysAsp: 4.198 ± 0.733
5.038LysGlu: 5.038 ± 1.584
1.679LysPhe: 1.679 ± 0.658
4.478LysGly: 4.478 ± 0.339
0.56LysHis: 0.56 ± 0.455
6.717LysIle: 6.717 ± 1.832
5.038LysLys: 5.038 ± 1.37
8.396LysLeu: 8.396 ± 0.505
1.399LysMet: 1.399 ± 0.923
6.157LysAsn: 6.157 ± 1.258
2.519LysPro: 2.519 ± 1.368
0.56LysGln: 0.56 ± 0.339
3.638LysArg: 3.638 ± 0.682
5.598LysSer: 5.598 ± 1.816
3.359LysThr: 3.359 ± 1.279
4.478LysVal: 4.478 ± 1.087
1.959LysTrp: 1.959 ± 0.993
5.598LysTyr: 5.598 ± 0.908
0.0LysXaa: 0.0 ± 0.0
Leu
3.359LeuAla: 3.359 ± 1.094
0.84LeuCys: 0.84 ± 0.301
7.557LeuAsp: 7.557 ± 0.156
6.157LeuGlu: 6.157 ± 2.4
4.198LeuPhe: 4.198 ± 1.449
6.997LeuGly: 6.997 ± 1.397
2.239LeuHis: 2.239 ± 0.566
9.796LeuIle: 9.796 ± 1.776
5.318LeuLys: 5.318 ± 1.532
8.676LeuLeu: 8.676 ± 1.318
4.198LeuMet: 4.198 ± 0.824
5.877LeuAsn: 5.877 ± 1.361
2.799LeuPro: 2.799 ± 0.999
1.679LeuGln: 1.679 ± 1.625
5.598LeuArg: 5.598 ± 1.438
8.676LeuSer: 8.676 ± 1.415
6.157LeuThr: 6.157 ± 1.866
2.239LeuVal: 2.239 ± 1.138
0.28LeuTrp: 0.28 ± 0.161
3.638LeuTyr: 3.638 ± 1.093
0.0LeuXaa: 0.0 ± 0.0
Met
1.959MetAla: 1.959 ± 0.814
0.28MetCys: 0.28 ± 0.161
0.84MetAsp: 0.84 ± 0.47
3.359MetGlu: 3.359 ± 1.739
1.12MetPhe: 1.12 ± 0.441
1.679MetGly: 1.679 ± 0.756
0.84MetHis: 0.84 ± 0.765
3.079MetIle: 3.079 ± 1.032
1.12MetLys: 1.12 ± 0.353
1.959MetLeu: 1.959 ± 0.683
1.399MetMet: 1.399 ± 0.804
2.519MetAsn: 2.519 ± 0.572
0.0MetPro: 0.0 ± 0.0
0.28MetGln: 0.28 ± 0.161
1.12MetArg: 1.12 ± 0.479
3.918MetSer: 3.918 ± 2.096
1.12MetThr: 1.12 ± 0.643
0.56MetVal: 0.56 ± 0.455
0.56MetTrp: 0.56 ± 0.339
1.12MetTyr: 1.12 ± 0.883
0.0MetXaa: 0.0 ± 0.0
Asn
1.679AsnAla: 1.679 ± 0.791
0.84AsnCys: 0.84 ± 0.301
2.799AsnAsp: 2.799 ± 0.273
1.959AsnGlu: 1.959 ± 1.081
3.079AsnPhe: 3.079 ± 0.635
1.959AsnGly: 1.959 ± 1.436
1.959AsnHis: 1.959 ± 0.555
7.557AsnIle: 7.557 ± 0.449
4.758AsnLys: 4.758 ± 1.392
5.318AsnLeu: 5.318 ± 0.88
2.239AsnMet: 2.239 ± 0.641
3.359AsnAsn: 3.359 ± 1.097
3.918AsnPro: 3.918 ± 0.715
1.679AsnGln: 1.679 ± 0.573
3.079AsnArg: 3.079 ± 1.545
3.918AsnSer: 3.918 ± 0.679
3.359AsnThr: 3.359 ± 1.031
3.359AsnVal: 3.359 ± 0.69
0.56AsnTrp: 0.56 ± 0.573
2.519AsnTyr: 2.519 ± 0.858
0.0AsnXaa: 0.0 ± 0.0
Pro
1.679ProAla: 1.679 ± 0.345
0.84ProCys: 0.84 ± 0.301
2.799ProAsp: 2.799 ± 0.918
2.519ProGlu: 2.519 ± 1.081
1.12ProPhe: 1.12 ± 0.344
1.12ProGly: 1.12 ± 1.215
1.959ProHis: 1.959 ± 0.626
2.799ProIle: 2.799 ± 1.139
2.799ProLys: 2.799 ± 0.835
5.598ProLeu: 5.598 ± 1.082
0.84ProMet: 0.84 ± 0.556
3.359ProAsn: 3.359 ± 1.207
1.959ProPro: 1.959 ± 1.884
1.12ProGln: 1.12 ± 0.516
1.679ProArg: 1.679 ± 0.489
5.038ProSer: 5.038 ± 0.931
2.519ProThr: 2.519 ± 0.801
3.079ProVal: 3.079 ± 1.355
0.84ProTrp: 0.84 ± 0.414
1.12ProTyr: 1.12 ± 0.353
0.0ProXaa: 0.0 ± 0.0
Gln
0.56GlnAla: 0.56 ± 0.322
0.56GlnCys: 0.56 ± 0.387
1.399GlnAsp: 1.399 ± 0.91
1.679GlnGlu: 1.679 ± 0.366
0.56GlnPhe: 0.56 ± 0.322
2.239GlnGly: 2.239 ± 1.366
0.56GlnHis: 0.56 ± 0.322
1.959GlnIle: 1.959 ± 0.354
2.239GlnLys: 2.239 ± 1.375
2.799GlnLeu: 2.799 ± 0.854
0.28GlnMet: 0.28 ± 0.495
1.12GlnAsn: 1.12 ± 0.801
1.679GlnPro: 1.679 ± 0.965
0.28GlnGln: 0.28 ± 0.495
1.399GlnArg: 1.399 ± 0.635
2.239GlnSer: 2.239 ± 1.287
0.56GlnThr: 0.56 ± 0.848
0.84GlnVal: 0.84 ± 0.301
0.28GlnTrp: 0.28 ± 0.495
1.399GlnTyr: 1.399 ± 0.505
0.0GlnXaa: 0.0 ± 0.0
Arg
2.239ArgAla: 2.239 ± 0.648
1.12ArgCys: 1.12 ± 0.344
2.519ArgAsp: 2.519 ± 0.846
2.799ArgGlu: 2.799 ± 1.608
1.959ArgPhe: 1.959 ± 0.898
2.519ArgGly: 2.519 ± 1.158
1.12ArgHis: 1.12 ± 0.643
4.478ArgIle: 4.478 ± 0.993
3.359ArgLys: 3.359 ± 1.482
2.519ArgLeu: 2.519 ± 0.88
1.399ArgMet: 1.399 ± 0.453
1.959ArgAsn: 1.959 ± 0.89
1.679ArgPro: 1.679 ± 0.518
0.56ArgGln: 0.56 ± 0.322
0.84ArgArg: 0.84 ± 0.47
4.758ArgSer: 4.758 ± 1.116
1.399ArgThr: 1.399 ± 0.59
3.638ArgVal: 3.638 ± 1.214
0.56ArgTrp: 0.56 ± 0.322
2.519ArgTyr: 2.519 ± 0.737
0.0ArgXaa: 0.0 ± 0.0
Ser
3.638SerAla: 3.638 ± 1.707
1.12SerCys: 1.12 ± 0.678
5.318SerAsp: 5.318 ± 1.324
4.758SerGlu: 4.758 ± 1.376
2.239SerPhe: 2.239 ± 0.322
3.638SerGly: 3.638 ± 0.835
1.959SerHis: 1.959 ± 0.806
8.396SerIle: 8.396 ± 1.171
7.277SerLys: 7.277 ± 1.125
12.035SerLeu: 12.035 ± 2.395
3.079SerMet: 3.079 ± 0.825
5.598SerAsn: 5.598 ± 1.935
5.877SerPro: 5.877 ± 0.967
1.399SerGln: 1.399 ± 0.525
5.598SerArg: 5.598 ± 1.507
8.956SerSer: 8.956 ± 2.516
5.318SerThr: 5.318 ± 1.475
4.198SerVal: 4.198 ± 0.783
1.959SerTrp: 1.959 ± 1.126
3.359SerTyr: 3.359 ± 0.421
0.0SerXaa: 0.0 ± 0.0
Thr
1.399ThrAla: 1.399 ± 0.505
0.28ThrCys: 0.28 ± 0.437
4.198ThrAsp: 4.198 ± 1.748
3.079ThrGlu: 3.079 ± 0.501
1.12ThrPhe: 1.12 ± 0.495
3.079ThrGly: 3.079 ± 1.835
1.399ThrHis: 1.399 ± 0.804
5.038ThrIle: 5.038 ± 1.666
3.638ThrLys: 3.638 ± 0.772
5.598ThrLeu: 5.598 ± 1.212
1.959ThrMet: 1.959 ± 0.74
1.12ThrAsn: 1.12 ± 0.495
1.679ThrPro: 1.679 ± 1.474
1.12ThrGln: 1.12 ± 0.535
1.959ThrArg: 1.959 ± 0.898
5.038ThrSer: 5.038 ± 2.496
2.799ThrThr: 2.799 ± 1.01
2.799ThrVal: 2.799 ± 0.854
0.84ThrTrp: 0.84 ± 0.414
2.239ThrTyr: 2.239 ± 1.021
0.0ThrXaa: 0.0 ± 0.0
Val
0.84ValAla: 0.84 ± 0.301
0.84ValCys: 0.84 ± 0.301
4.198ValAsp: 4.198 ± 0.995
4.198ValGlu: 4.198 ± 2.159
0.84ValPhe: 0.84 ± 0.798
2.519ValGly: 2.519 ± 0.7
0.56ValHis: 0.56 ± 0.339
5.038ValIle: 5.038 ± 1.375
4.758ValLys: 4.758 ± 1.664
5.318ValLeu: 5.318 ± 2.581
2.519ValMet: 2.519 ± 0.495
3.638ValAsn: 3.638 ± 1.172
1.959ValPro: 1.959 ± 0.44
0.84ValGln: 0.84 ± 0.796
0.84ValArg: 0.84 ± 0.485
6.157ValSer: 6.157 ± 2.334
1.959ValThr: 1.959 ± 1.063
2.799ValVal: 2.799 ± 0.783
0.84ValTrp: 0.84 ± 0.403
1.679ValTyr: 1.679 ± 0.602
0.0ValXaa: 0.0 ± 0.0
Trp
0.56TrpAla: 0.56 ± 0.322
0.56TrpCys: 0.56 ± 0.322
1.399TrpAsp: 1.399 ± 0.635
1.12TrpGlu: 1.12 ± 0.495
1.399TrpPhe: 1.399 ± 0.785
0.84TrpGly: 0.84 ± 0.483
0.28TrpHis: 0.28 ± 0.161
2.799TrpIle: 2.799 ± 1.881
1.399TrpLys: 1.399 ± 0.804
0.56TrpLeu: 0.56 ± 0.322
0.28TrpMet: 0.28 ± 0.437
1.679TrpAsn: 1.679 ± 0.756
0.56TrpPro: 0.56 ± 0.387
0.0TrpGln: 0.0 ± 0.0
0.28TrpArg: 0.28 ± 0.161
1.399TrpSer: 1.399 ± 0.525
0.84TrpThr: 0.84 ± 0.414
0.0TrpVal: 0.0 ± 0.0
0.28TrpTrp: 0.28 ± 0.437
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.519TyrAla: 2.519 ± 0.7
1.959TyrCys: 1.959 ± 0.953
1.679TyrAsp: 1.679 ± 0.753
0.56TyrGlu: 0.56 ± 0.339
2.799TyrPhe: 2.799 ± 1.397
0.84TyrGly: 0.84 ± 0.403
1.679TyrHis: 1.679 ± 0.573
3.079TyrIle: 3.079 ± 1.612
3.079TyrLys: 3.079 ± 0.925
3.918TyrLeu: 3.918 ± 1.175
1.12TyrMet: 1.12 ± 0.809
2.519TyrAsn: 2.519 ± 1.016
1.959TyrPro: 1.959 ± 0.88
3.079TyrGln: 3.079 ± 0.356
1.399TyrArg: 1.399 ± 0.59
5.598TyrSer: 5.598 ± 2.396
1.679TyrThr: 1.679 ± 0.573
2.519TyrVal: 2.519 ± 0.524
0.84TyrTrp: 0.84 ± 0.403
1.959TyrTyr: 1.959 ± 0.5
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3574 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski