Amino acid dipepetide frequency for Phialemoniopsis curvata

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.224AlaAla: 12.224 ± 0.083	1.208AlaCys: 1.208 ± 0.016	4.99AlaAsp: 4.99 ± 0.033	5.67AlaGlu: 5.67 ± 0.045	3.235AlaPhe: 3.235 ± 0.029	7.166AlaGly: 7.166 ± 0.043	1.964AlaHis: 1.964 ± 0.02	4.133AlaIle: 4.133 ± 0.029	4.091AlaLys: 4.091 ± 0.034	8.28AlaLeu: 8.28 ± 0.046	2.187AlaMet: 2.187 ± 0.021	2.973AlaAsn: 2.973 ± 0.023	5.497AlaPro: 5.497 ± 0.04	3.788AlaGln: 3.788 ± 0.031	5.788AlaArg: 5.788 ± 0.038	7.701AlaSer: 7.701 ± 0.045	5.545AlaThr: 5.545 ± 0.032	6.169AlaVal: 6.169 ± 0.033	1.296AlaTrp: 1.296 ± 0.016	2.246AlaTyr: 2.246 ± 0.019	0.0AlaXaa: 0.0 ± 0.0
Cys	1.064CysAla: 1.064 ± 0.015	0.268CysCys: 0.268 ± 0.007	0.702CysAsp: 0.702 ± 0.012	0.596CysGlu: 0.596 ± 0.01	0.554CysPhe: 0.554 ± 0.01	1.037CysGly: 1.037 ± 0.015	0.327CysHis: 0.327 ± 0.008	0.691CysIle: 0.691 ± 0.011	0.512CysLys: 0.512 ± 0.01	1.314CysLeu: 1.314 ± 0.016	0.286CysMet: 0.286 ± 0.006	0.426CysAsn: 0.426 ± 0.008	0.713CysPro: 0.713 ± 0.013	0.466CysGln: 0.466 ± 0.008	0.822CysArg: 0.822 ± 0.013	0.907CysSer: 0.907 ± 0.014	0.722CysThr: 0.722 ± 0.012	0.851CysVal: 0.851 ± 0.012	0.221CysTrp: 0.221 ± 0.006	0.366CysTyr: 0.366 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	5.239AspAla: 5.239 ± 0.026	0.67AspCys: 0.67 ± 0.012	4.557AspAsp: 4.557 ± 0.04	4.55AspGlu: 4.55 ± 0.034	2.196AspPhe: 2.196 ± 0.018	4.469AspGly: 4.469 ± 0.031	1.25AspHis: 1.25 ± 0.016	2.858AspIle: 2.858 ± 0.021	2.482AspLys: 2.482 ± 0.023	5.13AspLeu: 5.13 ± 0.033	1.335AspMet: 1.335 ± 0.014	1.771AspAsn: 1.771 ± 0.018	3.49AspPro: 3.49 ± 0.025	1.92AspGln: 1.92 ± 0.017	3.29AspArg: 3.29 ± 0.027	3.88AspSer: 3.88 ± 0.03	2.811AspThr: 2.811 ± 0.019	3.752AspVal: 3.752 ± 0.024	0.947AspTrp: 0.947 ± 0.014	1.533AspTyr: 1.533 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	5.858GluAla: 5.858 ± 0.044	0.634GluCys: 0.634 ± 0.01	4.143GluAsp: 4.143 ± 0.04	5.267GluGlu: 5.267 ± 0.053	1.811GluPhe: 1.811 ± 0.019	3.918GluGly: 3.918 ± 0.027	1.433GluHis: 1.433 ± 0.014	2.736GluIle: 2.736 ± 0.021	3.252GluLys: 3.252 ± 0.034	5.133GluLeu: 5.133 ± 0.034	1.456GluMet: 1.456 ± 0.017	1.914GluAsn: 1.914 ± 0.017	2.922GluPro: 2.922 ± 0.039	2.492GluGln: 2.492 ± 0.023	3.911GluArg: 3.911 ± 0.031	3.876GluSer: 3.876 ± 0.028	3.266GluThr: 3.266 ± 0.027	3.608GluVal: 3.608 ± 0.027	0.867GluTrp: 0.867 ± 0.01	1.546GluTyr: 1.546 ± 0.016	0.0GluXaa: 0.0 ± 0.0
Phe	3.225PheAla: 3.225 ± 0.025	0.558PheCys: 0.558 ± 0.01	2.283PheAsp: 2.283 ± 0.02	2.084PheGlu: 2.084 ± 0.02	1.596PhePhe: 1.596 ± 0.019	2.905PheGly: 2.905 ± 0.026	0.851PheHis: 0.851 ± 0.011	1.66PheIle: 1.66 ± 0.02	1.44PheLys: 1.44 ± 0.017	3.358PheLeu: 3.358 ± 0.029	0.805PheMet: 0.805 ± 0.013	1.298PheAsn: 1.298 ± 0.013	1.908PhePro: 1.908 ± 0.02	1.305PheGln: 1.305 ± 0.015	1.982PheArg: 1.982 ± 0.019	2.766PheSer: 2.766 ± 0.023	2.027PheThr: 2.027 ± 0.02	2.43PheVal: 2.43 ± 0.02	0.65PheTrp: 0.65 ± 0.011	1.061PheTyr: 1.061 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	6.582GlyAla: 6.582 ± 0.038	0.986GlyCys: 0.986 ± 0.015	4.038GlyAsp: 4.038 ± 0.027	3.782GlyGlu: 3.782 ± 0.028	2.881GlyPhe: 2.881 ± 0.026	7.482GlyGly: 7.482 ± 0.07	1.794GlyHis: 1.794 ± 0.018	3.344GlyIle: 3.344 ± 0.028	3.401GlyLys: 3.401 ± 0.03	6.376GlyLeu: 6.376 ± 0.04	1.723GlyMet: 1.723 ± 0.017	2.453GlyAsn: 2.453 ± 0.025	3.83GlyPro: 3.83 ± 0.036	2.797GlyGln: 2.797 ± 0.025	4.63GlyArg: 4.63 ± 0.034	5.993GlySer: 5.993 ± 0.041	4.087GlyThr: 4.087 ± 0.034	4.661GlyVal: 4.661 ± 0.029	1.228GlyTrp: 1.228 ± 0.016	2.1GlyTyr: 2.1 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	1.995HisAla: 1.995 ± 0.019	0.353HisCys: 0.353 ± 0.007	1.391HisAsp: 1.391 ± 0.018	1.312HisGlu: 1.312 ± 0.015	0.899HisPhe: 0.899 ± 0.012	1.882HisGly: 1.882 ± 0.017	0.982HisHis: 0.982 ± 0.017	1.135HisIle: 1.135 ± 0.014	0.879HisLys: 0.879 ± 0.012	2.188HisLeu: 2.188 ± 0.019	0.508HisMet: 0.508 ± 0.009	0.754HisAsn: 0.754 ± 0.011	1.676HisPro: 1.676 ± 0.018	1.022HisGln: 1.022 ± 0.015	1.595HisArg: 1.595 ± 0.017	1.712HisSer: 1.712 ± 0.017	1.19HisThr: 1.19 ± 0.014	1.475HisVal: 1.475 ± 0.016	0.367HisTrp: 0.367 ± 0.008	0.686HisTyr: 0.686 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	4.059IleAla: 4.059 ± 0.028	0.723IleCys: 0.723 ± 0.012	2.674IleAsp: 2.674 ± 0.021	2.535IleGlu: 2.535 ± 0.023	1.812IlePhe: 1.812 ± 0.019	3.049IleGly: 3.049 ± 0.027	1.078IleHis: 1.078 ± 0.014	2.19IleIle: 2.19 ± 0.023	1.947IleLys: 1.947 ± 0.019	4.128IleLeu: 4.128 ± 0.034	0.994IleMet: 0.994 ± 0.012	1.571IleAsn: 1.571 ± 0.016	2.819IlePro: 2.819 ± 0.023	1.676IleGln: 1.676 ± 0.016	2.588IleArg: 2.588 ± 0.02	3.356IleSer: 3.356 ± 0.025	2.603IleThr: 2.603 ± 0.027	3.001IleVal: 3.001 ± 0.025	0.687IleTrp: 0.687 ± 0.011	1.272IleTyr: 1.272 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	4.361LysAla: 4.361 ± 0.034	0.486LysCys: 0.486 ± 0.01	2.652LysAsp: 2.652 ± 0.023	3.02LysGlu: 3.02 ± 0.03	1.348LysPhe: 1.348 ± 0.016	2.961LysGly: 2.961 ± 0.025	1.052LysHis: 1.052 ± 0.015	2.007LysIle: 2.007 ± 0.019	3.029LysLys: 3.029 ± 0.05	3.738LysLeu: 3.738 ± 0.028	0.948LysMet: 0.948 ± 0.012	1.483LysAsn: 1.483 ± 0.019	2.564LysPro: 2.564 ± 0.024	1.716LysGln: 1.716 ± 0.019	3.112LysArg: 3.112 ± 0.028	3.118LysSer: 3.118 ± 0.03	2.604LysThr: 2.604 ± 0.019	2.674LysVal: 2.674 ± 0.023	0.633LysTrp: 0.633 ± 0.011	1.256LysTyr: 1.256 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	8.559LeuAla: 8.559 ± 0.046	1.246LeuCys: 1.246 ± 0.018	5.298LeuAsp: 5.298 ± 0.033	5.354LeuGlu: 5.354 ± 0.038	3.246LeuPhe: 3.246 ± 0.028	6.224LeuGly: 6.224 ± 0.036	2.209LeuHis: 2.209 ± 0.022	3.54LeuIle: 3.54 ± 0.029	3.778LeuLys: 3.778 ± 0.03	8.284LeuLeu: 8.284 ± 0.062	1.78LeuMet: 1.78 ± 0.02	2.833LeuAsn: 2.833 ± 0.02	5.574LeuPro: 5.574 ± 0.034	3.677LeuGln: 3.677 ± 0.031	5.926LeuArg: 5.926 ± 0.036	6.923LeuSer: 6.923 ± 0.036	4.568LeuThr: 4.568 ± 0.032	5.698LeuVal: 5.698 ± 0.035	1.229LeuTrp: 1.229 ± 0.015	2.281LeuTyr: 2.281 ± 0.02	0.0LeuXaa: 0.0 ± 0.0
Met	2.475MetAla: 2.475 ± 0.02	0.262MetCys: 0.262 ± 0.006	1.267MetAsp: 1.267 ± 0.016	1.219MetGlu: 1.219 ± 0.015	0.748MetPhe: 0.748 ± 0.012	1.575MetGly: 1.575 ± 0.017	0.505MetHis: 0.505 ± 0.009	0.949MetIle: 0.949 ± 0.012	0.915MetLys: 0.915 ± 0.012	1.887MetLeu: 1.887 ± 0.018	0.59MetMet: 0.59 ± 0.01	0.716MetAsn: 0.716 ± 0.012	1.354MetPro: 1.354 ± 0.018	0.858MetGln: 0.858 ± 0.013	1.333MetArg: 1.333 ± 0.014	1.814MetSer: 1.814 ± 0.017	1.317MetThr: 1.317 ± 0.016	1.349MetVal: 1.349 ± 0.015	0.27MetTrp: 0.27 ± 0.007	0.534MetTyr: 0.534 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	2.954AsnAla: 2.954 ± 0.024	0.439AsnCys: 0.439 ± 0.009	1.74AsnAsp: 1.74 ± 0.016	1.711AsnGlu: 1.711 ± 0.015	1.273AsnPhe: 1.273 ± 0.016	2.862AsnGly: 2.862 ± 0.028	0.75AsnHis: 0.75 ± 0.01	1.779AsnIle: 1.779 ± 0.019	1.393AsnLys: 1.393 ± 0.017	2.954AsnLeu: 2.954 ± 0.024	0.787AsnMet: 0.787 ± 0.013	1.319AsnAsn: 1.319 ± 0.019	2.218AsnPro: 2.218 ± 0.022	1.149AsnGln: 1.149 ± 0.014	1.755AsnArg: 1.755 ± 0.014	2.346AsnSer: 2.346 ± 0.023	1.915AsnThr: 1.915 ± 0.019	2.121AsnVal: 2.121 ± 0.019	0.503AsnTrp: 0.503 ± 0.009	0.949AsnTyr: 0.949 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	6.286ProAla: 6.286 ± 0.049	0.594ProCys: 0.594 ± 0.011	3.41ProAsp: 3.41 ± 0.025	3.901ProGlu: 3.901 ± 0.031	2.053ProPhe: 2.053 ± 0.02	4.533ProGly: 4.533 ± 0.038	1.344ProHis: 1.344 ± 0.014	2.278ProIle: 2.278 ± 0.02	2.452ProLys: 2.452 ± 0.023	4.799ProLeu: 4.799 ± 0.029	1.09ProMet: 1.09 ± 0.013	1.98ProAsn: 1.98 ± 0.023	5.707ProPro: 5.707 ± 0.065	2.556ProGln: 2.556 ± 0.032	3.693ProArg: 3.693 ± 0.032	5.797ProSer: 5.797 ± 0.04	3.82ProThr: 3.82 ± 0.031	3.787ProVal: 3.787 ± 0.03	0.775ProTrp: 0.775 ± 0.01	1.484ProTyr: 1.484 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.836GlnAla: 3.836 ± 0.032	0.469GlnCys: 0.469 ± 0.01	2.132GlnAsp: 2.132 ± 0.019	2.324GlnGlu: 2.324 ± 0.02	1.231GlnPhe: 1.231 ± 0.015	2.629GlnGly: 2.629 ± 0.026	1.119GlnHis: 1.119 ± 0.016	1.701GlnIle: 1.701 ± 0.017	1.789GlnLys: 1.789 ± 0.02	3.414GlnLeu: 3.414 ± 0.024	0.894GlnMet: 0.894 ± 0.015	1.332GlnAsn: 1.332 ± 0.017	2.647GlnPro: 2.647 ± 0.032	2.869GlnGln: 2.869 ± 0.059	2.666GlnArg: 2.666 ± 0.022	2.924GlnSer: 2.924 ± 0.024	2.208GlnThr: 2.208 ± 0.024	2.261GlnVal: 2.261 ± 0.02	0.587GlnTrp: 0.587 ± 0.01	1.101GlnTyr: 1.101 ± 0.013	0.0GlnXaa: 0.0 ± 0.0
Arg	5.443ArgAla: 5.443 ± 0.039	0.747ArgCys: 0.747 ± 0.012	3.712ArgAsp: 3.712 ± 0.032	3.904ArgGlu: 3.904 ± 0.034	2.117ArgPhe: 2.117 ± 0.019	4.111ArgGly: 4.111 ± 0.029	1.723ArgHis: 1.723 ± 0.018	2.699ArgIle: 2.699 ± 0.023	3.224ArgLys: 3.224 ± 0.029	5.75ArgLeu: 5.75 ± 0.04	1.349ArgMet: 1.349 ± 0.015	2.045ArgAsn: 2.045 ± 0.018	3.805ArgPro: 3.805 ± 0.032	2.717ArgGln: 2.717 ± 0.025	5.654ArgArg: 5.654 ± 0.042	4.677ArgSer: 4.677 ± 0.035	3.244ArgThr: 3.244 ± 0.024	3.596ArgVal: 3.596 ± 0.028	0.988ArgTrp: 0.988 ± 0.014	1.667ArgTyr: 1.667 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	6.995SerAla: 6.995 ± 0.039	0.891SerCys: 0.891 ± 0.015	3.987SerAsp: 3.987 ± 0.028	3.742SerGlu: 3.742 ± 0.029	2.873SerPhe: 2.873 ± 0.022	5.744SerGly: 5.744 ± 0.036	1.843SerHis: 1.843 ± 0.017	3.507SerIle: 3.507 ± 0.024	3.337SerLys: 3.337 ± 0.027	6.877SerLeu: 6.877 ± 0.04	1.693SerMet: 1.693 ± 0.016	2.515SerAsn: 2.515 ± 0.021	5.493SerPro: 5.493 ± 0.049	3.099SerGln: 3.099 ± 0.025	4.981SerArg: 4.981 ± 0.035	8.598SerSer: 8.598 ± 0.069	5.127SerThr: 5.127 ± 0.047	4.426SerVal: 4.426 ± 0.028	1.132SerTrp: 1.132 ± 0.014	1.906SerTyr: 1.906 ± 0.017	0.0SerXaa: 0.0 ± 0.0
Thr	5.579ThrAla: 5.579 ± 0.035	0.778ThrCys: 0.778 ± 0.012	2.742ThrAsp: 2.742 ± 0.024	2.908ThrGlu: 2.908 ± 0.028	2.14ThrPhe: 2.14 ± 0.021	4.276ThrGly: 4.276 ± 0.031	1.174ThrHis: 1.174 ± 0.013	2.745ThrIle: 2.745 ± 0.029	2.33ThrLys: 2.33 ± 0.019	4.833ThrLeu: 4.833 ± 0.032	1.179ThrMet: 1.179 ± 0.013	1.868ThrAsn: 1.868 ± 0.018	4.214ThrPro: 4.214 ± 0.041	1.974ThrGln: 1.974 ± 0.023	3.099ThrArg: 3.099 ± 0.024	4.978ThrSer: 4.978 ± 0.039	4.223ThrThr: 4.223 ± 0.046	3.738ThrVal: 3.738 ± 0.033	0.846ThrTrp: 0.846 ± 0.013	1.544ThrTyr: 1.544 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	5.987ValAla: 5.987 ± 0.035	0.891ValCys: 0.891 ± 0.014	3.858ValAsp: 3.858 ± 0.026	3.846ValGlu: 3.846 ± 0.025	2.466ValPhe: 2.466 ± 0.022	4.29ValGly: 4.29 ± 0.03	1.468ValHis: 1.468 ± 0.016	2.822ValIle: 2.822 ± 0.024	2.742ValLys: 2.742 ± 0.02	5.83ValLeu: 5.83 ± 0.035	1.35ValMet: 1.35 ± 0.016	2.089ValAsn: 2.089 ± 0.02	3.796ValPro: 3.796 ± 0.026	2.403ValGln: 2.403 ± 0.018	3.717ValArg: 3.717 ± 0.028	4.474ValSer: 4.474 ± 0.028	3.483ValThr: 3.483 ± 0.03	4.644ValVal: 4.644 ± 0.032	0.912ValTrp: 0.912 ± 0.013	1.725ValTyr: 1.725 ± 0.017	0.0ValXaa: 0.0 ± 0.0
Trp	1.255TrpAla: 1.255 ± 0.014	0.208TrpCys: 0.208 ± 0.005	0.934TrpAsp: 0.934 ± 0.014	0.845TrpGlu: 0.845 ± 0.014	0.55TrpPhe: 0.55 ± 0.01	0.974TrpGly: 0.974 ± 0.015	0.394TrpHis: 0.394 ± 0.008	0.723TrpIle: 0.723 ± 0.011	0.753TrpLys: 0.753 ± 0.01	1.396TrpLeu: 1.396 ± 0.017	0.37TrpMet: 0.37 ± 0.008	0.592TrpAsn: 0.592 ± 0.01	0.655TrpPro: 0.655 ± 0.011	0.593TrpGln: 0.593 ± 0.009	1.011TrpArg: 1.011 ± 0.014	1.03TrpSer: 1.03 ± 0.013	0.93TrpThr: 0.93 ± 0.013	0.925TrpVal: 0.925 ± 0.013	0.289TrpTrp: 0.289 ± 0.007	0.443TrpTyr: 0.443 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.179TyrAla: 2.179 ± 0.021	0.431TyrCys: 0.431 ± 0.009	1.622TyrAsp: 1.622 ± 0.019	1.472TyrGlu: 1.472 ± 0.015	1.163TyrPhe: 1.163 ± 0.015	2.084TyrGly: 2.084 ± 0.021	0.739TyrHis: 0.739 ± 0.011	1.266TyrIle: 1.266 ± 0.015	1.014TyrLys: 1.014 ± 0.016	2.558TyrLeu: 2.558 ± 0.024	0.611TyrMet: 0.611 ± 0.01	0.985TyrAsn: 0.985 ± 0.011	1.456TyrPro: 1.456 ± 0.017	1.058TyrGln: 1.058 ± 0.013	1.618TyrArg: 1.618 ± 0.017	1.895TyrSer: 1.895 ± 0.017	1.477TyrThr: 1.477 ± 0.016	1.629TyrVal: 1.629 ± 0.017	0.442TyrTrp: 0.442 ± 0.009	0.918TyrTyr: 0.918 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 12104 proteins (6446461 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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