Amino acid dipepetide frequency for Saitozyma podzolica

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.589AlaAla: 10.589 ± 0.066	1.026AlaCys: 1.026 ± 0.015	4.618AlaAsp: 4.618 ± 0.033	5.918AlaGlu: 5.918 ± 0.047	3.212AlaPhe: 3.212 ± 0.031	7.582AlaGly: 7.582 ± 0.05	2.054AlaHis: 2.054 ± 0.025	4.072AlaIle: 4.072 ± 0.028	4.086AlaLys: 4.086 ± 0.036	8.591AlaLeu: 8.591 ± 0.047	2.276AlaMet: 2.276 ± 0.022	2.786AlaAsn: 2.786 ± 0.025	6.127AlaPro: 6.127 ± 0.057	3.588AlaGln: 3.588 ± 0.038	5.9AlaArg: 5.9 ± 0.035	8.803AlaSer: 8.803 ± 0.073	5.54AlaThr: 5.54 ± 0.037	5.974AlaVal: 5.974 ± 0.044	1.342AlaTrp: 1.342 ± 0.016	2.157AlaTyr: 2.157 ± 0.019	0.0AlaXaa: 0.0 ± 0.0
Cys	0.862CysAla: 0.862 ± 0.014	0.204CysCys: 0.204 ± 0.007	0.531CysAsp: 0.531 ± 0.011	0.516CysGlu: 0.516 ± 0.011	0.474CysPhe: 0.474 ± 0.012	0.855CysGly: 0.855 ± 0.015	0.265CysHis: 0.265 ± 0.007	0.552CysIle: 0.552 ± 0.012	0.378CysLys: 0.378 ± 0.009	1.107CysLeu: 1.107 ± 0.017	0.237CysMet: 0.237 ± 0.007	0.299CysAsn: 0.299 ± 0.008	0.594CysPro: 0.594 ± 0.013	0.346CysGln: 0.346 ± 0.008	0.613CysArg: 0.613 ± 0.013	0.769CysSer: 0.769 ± 0.014	0.589CysThr: 0.589 ± 0.012	0.757CysVal: 0.757 ± 0.015	0.203CysTrp: 0.203 ± 0.007	0.283CysTyr: 0.283 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.924AspAla: 4.924 ± 0.035	0.512AspCys: 0.512 ± 0.012	3.975AspAsp: 3.975 ± 0.049	4.904AspGlu: 4.904 ± 0.05	1.895AspPhe: 1.895 ± 0.019	4.375AspGly: 4.375 ± 0.033	1.255AspHis: 1.255 ± 0.017	2.367AspIle: 2.367 ± 0.022	2.18AspLys: 2.18 ± 0.025	5.087AspLeu: 5.087 ± 0.036	1.224AspMet: 1.224 ± 0.017	1.388AspAsn: 1.388 ± 0.017	3.605AspPro: 3.605 ± 0.031	1.736AspGln: 1.736 ± 0.02	3.239AspArg: 3.239 ± 0.03	3.617AspSer: 3.617 ± 0.035	2.715AspThr: 2.715 ± 0.027	3.902AspVal: 3.902 ± 0.03	0.926AspTrp: 0.926 ± 0.014	1.259AspTyr: 1.259 ± 0.016	0.0AspXaa: 0.0 ± 0.0
Glu	5.956GluAla: 5.956 ± 0.05	0.506GluCys: 0.506 ± 0.01	4.245GluAsp: 4.245 ± 0.047	5.69GluGlu: 5.69 ± 0.063	1.505GluPhe: 1.505 ± 0.018	4.74GluGly: 4.74 ± 0.041	1.402GluHis: 1.402 ± 0.018	2.54GluIle: 2.54 ± 0.025	2.903GluLys: 2.903 ± 0.032	5.065GluLeu: 5.065 ± 0.038	1.541GluMet: 1.541 ± 0.016	1.526GluAsn: 1.526 ± 0.018	2.832GluPro: 2.832 ± 0.026	2.27GluGln: 2.27 ± 0.025	4.374GluArg: 4.374 ± 0.032	4.041GluSer: 4.041 ± 0.034	3.209GluThr: 3.209 ± 0.026	4.067GluVal: 4.067 ± 0.034	0.978GluTrp: 0.978 ± 0.014	1.408GluTyr: 1.408 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	3.19PheAla: 3.19 ± 0.025	0.457PheCys: 0.457 ± 0.01	2.069PheAsp: 2.069 ± 0.023	1.856PheGlu: 1.856 ± 0.024	1.445PhePhe: 1.445 ± 0.019	2.944PheGly: 2.944 ± 0.035	0.793PheHis: 0.793 ± 0.014	1.472PheIle: 1.472 ± 0.024	1.194PheLys: 1.194 ± 0.016	3.083PheLeu: 3.083 ± 0.029	0.644PheMet: 0.644 ± 0.012	1.094PheAsn: 1.094 ± 0.016	1.903PhePro: 1.903 ± 0.018	1.093PheGln: 1.093 ± 0.014	1.807PheArg: 1.807 ± 0.017	2.653PheSer: 2.653 ± 0.024	1.913PheThr: 1.913 ± 0.02	2.316PheVal: 2.316 ± 0.023	0.576PheTrp: 0.576 ± 0.01	0.903PheTyr: 0.903 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	6.688GlyAla: 6.688 ± 0.043	0.823GlyCys: 0.823 ± 0.014	4.024GlyAsp: 4.024 ± 0.029	4.739GlyGlu: 4.739 ± 0.039	2.71GlyPhe: 2.71 ± 0.027	7.618GlyGly: 7.618 ± 0.076	1.773GlyHis: 1.773 ± 0.022	3.35GlyIle: 3.35 ± 0.03	3.772GlyLys: 3.772 ± 0.036	6.689GlyLeu: 6.689 ± 0.046	2.024GlyMet: 2.024 ± 0.028	2.328GlyAsn: 2.328 ± 0.027	4.127GlyPro: 4.127 ± 0.034	2.741GlyGln: 2.741 ± 0.027	4.824GlyArg: 4.824 ± 0.036	6.768GlySer: 6.768 ± 0.039	4.546GlyThr: 4.546 ± 0.031	5.331GlyVal: 5.331 ± 0.037	1.462GlyTrp: 1.462 ± 0.021	2.07GlyTyr: 2.07 ± 0.022	0.0GlyXaa: 0.0 ± 0.0
His	2.148HisAla: 2.148 ± 0.027	0.263HisCys: 0.263 ± 0.007	1.245HisAsp: 1.245 ± 0.018	1.224HisGlu: 1.224 ± 0.015	0.827HisPhe: 0.827 ± 0.014	1.79HisGly: 1.79 ± 0.022	0.883HisHis: 0.883 ± 0.017	1.035HisIle: 1.035 ± 0.015	0.722HisLys: 0.722 ± 0.013	2.577HisLeu: 2.577 ± 0.023	0.418HisMet: 0.418 ± 0.009	0.621HisAsn: 0.621 ± 0.012	2.16HisPro: 2.16 ± 0.024	0.872HisGln: 0.872 ± 0.015	1.613HisArg: 1.613 ± 0.018	1.858HisSer: 1.858 ± 0.024	1.312HisThr: 1.312 ± 0.02	1.488HisVal: 1.488 ± 0.017	0.319HisTrp: 0.319 ± 0.009	0.554HisTyr: 0.554 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.057IleAla: 4.057 ± 0.035	0.59IleCys: 0.59 ± 0.011	2.459IleAsp: 2.459 ± 0.024	2.361IleGlu: 2.361 ± 0.024	1.56IlePhe: 1.56 ± 0.019	3.133IleGly: 3.133 ± 0.034	0.996IleHis: 0.996 ± 0.014	2.038IleIle: 2.038 ± 0.026	1.752IleLys: 1.752 ± 0.02	3.842IleLeu: 3.842 ± 0.036	0.867IleMet: 0.867 ± 0.013	1.396IleAsn: 1.396 ± 0.016	3.039IlePro: 3.039 ± 0.025	1.363IleGln: 1.363 ± 0.02	2.546IleArg: 2.546 ± 0.021	3.317IleSer: 3.317 ± 0.03	2.533IleThr: 2.533 ± 0.024	2.935IleVal: 2.935 ± 0.031	0.622IleTrp: 0.622 ± 0.012	1.065IleTyr: 1.065 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	4.182LysAla: 4.182 ± 0.034	0.337LysCys: 0.337 ± 0.01	2.3LysAsp: 2.3 ± 0.027	2.85LysGlu: 2.85 ± 0.03	1.033LysPhe: 1.033 ± 0.016	3.205LysGly: 3.205 ± 0.034	0.946LysHis: 0.946 ± 0.015	1.566LysIle: 1.566 ± 0.019	2.446LysLys: 2.446 ± 0.034	3.34LysLeu: 3.34 ± 0.032	0.855LysMet: 0.855 ± 0.014	1.043LysAsn: 1.043 ± 0.015	2.417LysPro: 2.417 ± 0.029	1.39LysGln: 1.39 ± 0.016	3.196LysArg: 3.196 ± 0.028	2.862LysSer: 2.862 ± 0.028	2.306LysThr: 2.306 ± 0.024	2.706LysVal: 2.706 ± 0.029	0.62LysTrp: 0.62 ± 0.013	0.973LysTyr: 0.973 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	9.018LeuAla: 9.018 ± 0.048	1.076LeuCys: 1.076 ± 0.014	5.143LeuAsp: 5.143 ± 0.038	5.213LeuGlu: 5.213 ± 0.041	3.106LeuPhe: 3.106 ± 0.027	6.744LeuGly: 6.744 ± 0.039	2.271LeuHis: 2.271 ± 0.024	3.576LeuIle: 3.576 ± 0.033	3.303LeuLys: 3.303 ± 0.031	8.571LeuLeu: 8.571 ± 0.065	1.649LeuMet: 1.649 ± 0.02	2.626LeuAsn: 2.626 ± 0.027	6.748LeuPro: 6.748 ± 0.065	3.219LeuGln: 3.219 ± 0.029	5.973LeuArg: 5.973 ± 0.038	7.785LeuSer: 7.785 ± 0.049	4.782LeuThr: 4.782 ± 0.033	5.845LeuVal: 5.845 ± 0.039	1.128LeuTrp: 1.128 ± 0.015	2.045LeuTyr: 2.045 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	2.054MetAla: 2.054 ± 0.022	0.233MetCys: 0.233 ± 0.007	1.194MetAsp: 1.194 ± 0.017	1.183MetGlu: 1.183 ± 0.017	0.703MetPhe: 0.703 ± 0.012	1.721MetGly: 1.721 ± 0.025	0.365MetHis: 0.365 ± 0.008	0.937MetIle: 0.937 ± 0.013	0.717MetLys: 0.717 ± 0.011	1.828MetLeu: 1.828 ± 0.022	0.585MetMet: 0.585 ± 0.012	0.564MetAsn: 0.564 ± 0.012	1.424MetPro: 1.424 ± 0.019	0.695MetGln: 0.695 ± 0.014	1.325MetArg: 1.325 ± 0.015	2.207MetSer: 2.207 ± 0.021	1.364MetThr: 1.364 ± 0.018	1.274MetVal: 1.274 ± 0.016	0.294MetTrp: 0.294 ± 0.008	0.47MetTyr: 0.47 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	2.819AsnAla: 2.819 ± 0.024	0.29AsnCys: 0.29 ± 0.008	1.475AsnAsp: 1.475 ± 0.016	1.461AsnGlu: 1.461 ± 0.015	1.005AsnPhe: 1.005 ± 0.016	2.835AsnGly: 2.835 ± 0.03	0.67AsnHis: 0.67 ± 0.011	1.339AsnIle: 1.339 ± 0.018	1.079AsnLys: 1.079 ± 0.014	2.679AsnLeu: 2.679 ± 0.024	0.58AsnMet: 0.58 ± 0.012	0.893AsnAsn: 0.893 ± 0.015	2.22AsnPro: 2.22 ± 0.02	0.975AsnGln: 0.975 ± 0.017	1.574AsnArg: 1.574 ± 0.019	2.031AsnSer: 2.031 ± 0.023	1.706AsnThr: 1.706 ± 0.019	1.998AsnVal: 1.998 ± 0.023	0.431AsnTrp: 0.431 ± 0.009	0.726AsnTyr: 0.726 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	6.678ProAla: 6.678 ± 0.058	0.461ProCys: 0.461 ± 0.01	3.319ProAsp: 3.319 ± 0.028	3.74ProGlu: 3.74 ± 0.029	2.132ProPhe: 2.132 ± 0.019	4.688ProGly: 4.688 ± 0.039	1.692ProHis: 1.692 ± 0.023	2.705ProIle: 2.705 ± 0.028	2.34ProLys: 2.34 ± 0.025	5.781ProLeu: 5.781 ± 0.041	1.171ProMet: 1.171 ± 0.019	2.051ProAsn: 2.051 ± 0.022	6.934ProPro: 6.934 ± 0.086	2.323ProGln: 2.323 ± 0.027	4.143ProArg: 4.143 ± 0.035	8.185ProSer: 8.185 ± 0.075	4.97ProThr: 4.97 ± 0.038	3.976ProVal: 3.976 ± 0.033	0.739ProTrp: 0.739 ± 0.013	1.471ProTyr: 1.471 ± 0.017	0.0ProXaa: 0.0 ± 0.0
Gln	3.76GlnAla: 3.76 ± 0.035	0.356GlnCys: 0.356 ± 0.009	1.71GlnAsp: 1.71 ± 0.017	1.854GlnGlu: 1.854 ± 0.021	0.959GlnPhe: 0.959 ± 0.015	2.567GlnGly: 2.567 ± 0.03	0.985GlnHis: 0.985 ± 0.013	1.458GlnIle: 1.458 ± 0.016	1.207GlnLys: 1.207 ± 0.016	3.196GlnLeu: 3.196 ± 0.031	0.758GlnMet: 0.758 ± 0.016	0.998GlnAsn: 0.998 ± 0.016	2.62GlnPro: 2.62 ± 0.033	1.894GlnGln: 1.894 ± 0.062	2.366GlnArg: 2.366 ± 0.025	2.891GlnSer: 2.891 ± 0.027	2.143GlnThr: 2.143 ± 0.023	2.182GlnVal: 2.182 ± 0.023	0.553GlnTrp: 0.553 ± 0.011	0.895GlnTyr: 0.895 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	5.706ArgAla: 5.706 ± 0.035	0.633ArgCys: 0.633 ± 0.012	3.51ArgAsp: 3.51 ± 0.031	4.091ArgGlu: 4.091 ± 0.036	1.981ArgPhe: 1.981 ± 0.021	4.54ArgGly: 4.54 ± 0.037	1.605ArgHis: 1.605 ± 0.02	2.622ArgIle: 2.622 ± 0.025	3.115ArgLys: 3.115 ± 0.029	5.842ArgLeu: 5.842 ± 0.039	1.401ArgMet: 1.401 ± 0.015	1.742ArgAsn: 1.742 ± 0.017	4.308ArgPro: 4.308 ± 0.037	2.382ArgGln: 2.382 ± 0.021	5.822ArgArg: 5.822 ± 0.05	5.319ArgSer: 5.319 ± 0.048	3.533ArgThr: 3.533 ± 0.03	3.741ArgVal: 3.741 ± 0.032	1.039ArgTrp: 1.039 ± 0.015	1.486ArgTyr: 1.486 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	8.618SerAla: 8.618 ± 0.068	0.76SerCys: 0.76 ± 0.013	4.16SerAsp: 4.16 ± 0.035	4.047SerGlu: 4.047 ± 0.03	2.87SerPhe: 2.87 ± 0.027	6.704SerGly: 6.704 ± 0.052	2.106SerHis: 2.106 ± 0.024	3.485SerIle: 3.485 ± 0.037	3.094SerLys: 3.094 ± 0.03	7.598SerLeu: 7.598 ± 0.05	1.549SerMet: 1.549 ± 0.019	2.473SerAsn: 2.473 ± 0.024	6.926SerPro: 6.926 ± 0.065	2.973SerGln: 2.973 ± 0.034	5.441SerArg: 5.441 ± 0.042	10.398SerSer: 10.398 ± 0.098	6.28SerThr: 6.28 ± 0.046	4.859SerVal: 4.859 ± 0.041	1.104SerTrp: 1.104 ± 0.017	1.839SerTyr: 1.839 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	5.733ThrAla: 5.733 ± 0.039	0.648ThrCys: 0.648 ± 0.012	2.794ThrAsp: 2.794 ± 0.025	2.729ThrGlu: 2.729 ± 0.026	2.157ThrPhe: 2.157 ± 0.023	4.545ThrGly: 4.545 ± 0.031	1.397ThrHis: 1.397 ± 0.017	2.72ThrIle: 2.72 ± 0.025	2.113ThrLys: 2.113 ± 0.022	5.325ThrLeu: 5.325 ± 0.035	1.099ThrMet: 1.099 ± 0.016	1.722ThrAsn: 1.722 ± 0.02	5.172ThrPro: 5.172 ± 0.042	1.88ThrGln: 1.88 ± 0.024	3.317ThrArg: 3.317 ± 0.029	6.035ThrSer: 6.035 ± 0.048	4.232ThrThr: 4.232 ± 0.043	3.652ThrVal: 3.652 ± 0.03	0.825ThrTrp: 0.825 ± 0.014	1.483ThrTyr: 1.483 ± 0.022	0.0ThrXaa: 0.0 ± 0.0
Val	5.845ValAla: 5.845 ± 0.039	0.759ValCys: 0.759 ± 0.014	3.92ValAsp: 3.92 ± 0.029	4.221ValGlu: 4.221 ± 0.037	2.32ValPhe: 2.32 ± 0.028	4.867ValGly: 4.867 ± 0.031	1.466ValHis: 1.466 ± 0.016	2.887ValIle: 2.887 ± 0.029	2.669ValLys: 2.669 ± 0.025	5.905ValLeu: 5.905 ± 0.039	1.41ValMet: 1.41 ± 0.015	1.884ValAsn: 1.884 ± 0.023	4.297ValPro: 4.297 ± 0.034	2.293ValGln: 2.293 ± 0.02	3.828ValArg: 3.828 ± 0.029	4.883ValSer: 4.883 ± 0.034	3.471ValThr: 3.471 ± 0.029	4.696ValVal: 4.696 ± 0.037	0.976ValTrp: 0.976 ± 0.016	1.56ValTyr: 1.56 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.259TrpAla: 1.259 ± 0.017	0.196TrpCys: 0.196 ± 0.006	0.923TrpAsp: 0.923 ± 0.014	0.935TrpGlu: 0.935 ± 0.014	0.509TrpPhe: 0.509 ± 0.01	1.07TrpGly: 1.07 ± 0.017	0.312TrpHis: 0.312 ± 0.009	0.67TrpIle: 0.67 ± 0.012	0.709TrpLys: 0.709 ± 0.012	1.331TrpLeu: 1.331 ± 0.019	0.366TrpMet: 0.366 ± 0.01	0.538TrpAsn: 0.538 ± 0.01	0.611TrpPro: 0.611 ± 0.012	0.509TrpGln: 0.509 ± 0.01	1.054TrpArg: 1.054 ± 0.014	1.159TrpSer: 1.159 ± 0.015	0.983TrpThr: 0.983 ± 0.015	0.986TrpVal: 0.986 ± 0.014	0.346TrpTrp: 0.346 ± 0.008	0.4TrpTyr: 0.4 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.156TyrAla: 2.156 ± 0.025	0.305TyrCys: 0.305 ± 0.008	1.47TyrAsp: 1.47 ± 0.02	1.264TyrGlu: 1.264 ± 0.016	1.003TyrPhe: 1.003 ± 0.016	1.881TyrGly: 1.881 ± 0.024	0.69TyrHis: 0.69 ± 0.012	1.079TyrIle: 1.079 ± 0.017	0.792TyrLys: 0.792 ± 0.012	2.386TyrLeu: 2.386 ± 0.027	0.482TyrMet: 0.482 ± 0.011	0.816TyrAsn: 0.816 ± 0.012	1.437TyrPro: 1.437 ± 0.019	0.811TyrGln: 0.811 ± 0.016	1.467TyrArg: 1.467 ± 0.02	1.702TyrSer: 1.702 ± 0.02	1.452TyrThr: 1.452 ± 0.02	1.47TyrVal: 1.47 ± 0.019	0.382TyrTrp: 0.382 ± 0.01	0.714TyrTyr: 0.714 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 10205 proteins (5014707 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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