Amino acid dipepetide frequency for Lishi Spider Virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.314AlaAla: 1.314 ± 0.698
0.657AlaCys: 0.657 ± 0.309
0.657AlaAsp: 0.657 ± 0.349
2.3AlaGlu: 2.3 ± 0.272
0.657AlaPhe: 0.657 ± 0.349
1.643AlaGly: 1.643 ± 0.603
0.657AlaHis: 0.657 ± 0.309
2.958AlaIle: 2.958 ± 1.44
1.643AlaLys: 1.643 ± 1.111
2.958AlaLeu: 2.958 ± 1.295
0.329AlaMet: 0.329 ± 0.155
0.986AlaAsn: 0.986 ± 0.464
0.329AlaPro: 0.329 ± 0.672
0.329AlaGln: 0.329 ± 0.155
0.329AlaArg: 0.329 ± 0.155
2.958AlaSer: 2.958 ± 0.586
0.986AlaThr: 0.986 ± 0.268
1.314AlaVal: 1.314 ± 0.263
0.0AlaTrp: 0.0 ± 0.0
0.657AlaTyr: 0.657 ± 0.349
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.314CysAsp: 1.314 ± 0.698
1.972CysGlu: 1.972 ± 0.628
1.314CysPhe: 1.314 ± 0.619
0.986CysGly: 0.986 ± 0.268
0.329CysHis: 0.329 ± 0.155
1.643CysIle: 1.643 ± 0.773
1.643CysLys: 1.643 ± 0.557
2.3CysLeu: 2.3 ± 0.948
0.0CysMet: 0.0 ± 0.0
0.657CysAsn: 0.657 ± 0.349
0.657CysPro: 0.657 ± 0.309
0.329CysGln: 0.329 ± 0.469
0.329CysArg: 0.329 ± 0.155
2.629CysSer: 2.629 ± 0.918
0.329CysThr: 0.329 ± 0.155
0.0CysVal: 0.0 ± 0.0
0.329CysTrp: 0.329 ± 0.469
0.329CysTyr: 0.329 ± 0.155
0.0CysXaa: 0.0 ± 0.0
Asp
1.314AspAla: 1.314 ± 0.619
0.0AspCys: 0.0 ± 0.0
3.943AspAsp: 3.943 ± 0.804
1.972AspGlu: 1.972 ± 0.628
1.972AspPhe: 1.972 ± 0.928
0.329AspGly: 0.329 ± 0.155
0.657AspHis: 0.657 ± 0.309
4.601AspIle: 4.601 ± 0.698
4.929AspLys: 4.929 ± 1.016
7.23AspLeu: 7.23 ± 0.751
1.314AspMet: 1.314 ± 0.263
4.929AspAsn: 4.929 ± 1.919
2.3AspPro: 2.3 ± 0.591
2.3AspGln: 2.3 ± 1.083
2.629AspArg: 2.629 ± 0.526
4.601AspSer: 4.601 ± 1.85
3.615AspThr: 3.615 ± 0.028
1.972AspVal: 1.972 ± 0.456
0.657AspTrp: 0.657 ± 0.349
3.943AspTyr: 3.943 ± 0.989
0.0AspXaa: 0.0 ± 0.0
Glu
1.972GluAla: 1.972 ± 0.628
0.986GluCys: 0.986 ± 0.464
3.615GluAsp: 3.615 ± 0.028
4.272GluGlu: 4.272 ± 1.525
2.958GluPhe: 2.958 ± 0.376
1.314GluGly: 1.314 ± 0.619
1.972GluHis: 1.972 ± 1.108
5.587GluIle: 5.587 ± 1.526
7.23GluLys: 7.23 ± 0.662
6.901GluLeu: 6.901 ± 1.587
1.643GluMet: 1.643 ± 0.339
4.272GluAsn: 4.272 ± 1.59
1.643GluPro: 1.643 ± 0.603
1.314GluGln: 1.314 ± 1.058
2.958GluArg: 2.958 ± 1.44
6.572GluSer: 6.572 ± 1.61
3.615GluThr: 3.615 ± 0.028
4.272GluVal: 4.272 ± 0.91
0.657GluTrp: 0.657 ± 0.309
2.3GluTyr: 2.3 ± 0.508
0.0GluXaa: 0.0 ± 0.0
Phe
1.972PheAla: 1.972 ± 0.456
1.314PheCys: 1.314 ± 0.619
1.314PheAsp: 1.314 ± 0.263
2.958PheGlu: 2.958 ± 0.803
2.629PhePhe: 2.629 ± 0.733
1.643PheGly: 1.643 ± 0.557
0.986PheHis: 0.986 ± 0.716
3.286PheIle: 3.286 ± 0.72
3.286PheLys: 3.286 ± 0.805
3.943PheLeu: 3.943 ± 0.912
0.657PheMet: 0.657 ± 0.587
2.958PheAsn: 2.958 ± 0.88
1.643PhePro: 1.643 ± 0.444
3.286PheGln: 3.286 ± 1.114
2.3PheArg: 2.3 ± 0.272
4.929PheSer: 4.929 ± 1.222
2.958PheThr: 2.958 ± 0.376
1.972PheVal: 1.972 ± 0.535
0.657PheTrp: 0.657 ± 0.309
2.3PheTyr: 2.3 ± 0.508
0.0PheXaa: 0.0 ± 0.0
Gly
1.314GlyAla: 1.314 ± 1.174
1.643GlyCys: 1.643 ± 0.773
1.972GlyAsp: 1.972 ± 0.456
1.972GlyGlu: 1.972 ± 0.334
0.657GlyPhe: 0.657 ± 0.349
2.958GlyGly: 2.958 ± 0.376
0.986GlyHis: 0.986 ± 0.464
4.272GlyIle: 4.272 ± 1.59
3.286GlyLys: 3.286 ± 0.805
4.601GlyLeu: 4.601 ± 0.247
1.314GlyMet: 1.314 ± 1.174
1.972GlyAsn: 1.972 ± 0.334
0.329GlyPro: 0.329 ± 0.155
1.643GlyGln: 1.643 ± 0.773
0.657GlyArg: 0.657 ± 0.309
3.943GlySer: 3.943 ± 1.379
1.643GlyThr: 1.643 ± 0.444
2.3GlyVal: 2.3 ± 0.948
0.657GlyTrp: 0.657 ± 0.349
1.972GlyTyr: 1.972 ± 0.928
0.0GlyXaa: 0.0 ± 0.0
His
0.986HisAla: 0.986 ± 0.813
0.986HisCys: 0.986 ± 0.268
0.657HisAsp: 0.657 ± 0.587
1.314HisGlu: 1.314 ± 0.575
1.643HisPhe: 1.643 ± 0.339
0.329HisGly: 0.329 ± 0.469
0.657HisHis: 0.657 ± 0.938
2.629HisIle: 2.629 ± 0.733
1.972HisLys: 1.972 ± 0.535
1.972HisLeu: 1.972 ± 0.535
1.314HisMet: 1.314 ± 1.148
0.986HisAsn: 0.986 ± 0.268
1.972HisPro: 1.972 ± 0.456
1.643HisGln: 1.643 ± 0.444
0.657HisArg: 0.657 ± 0.309
1.643HisSer: 1.643 ± 0.339
1.314HisThr: 1.314 ± 0.575
0.986HisVal: 0.986 ± 0.268
0.0HisTrp: 0.0 ± 0.0
1.314HisTyr: 1.314 ± 0.263
0.0HisXaa: 0.0 ± 0.0
Ile
1.972IleAla: 1.972 ± 1.625
1.972IleCys: 1.972 ± 0.334
3.286IleAsp: 3.286 ± 0.131
6.572IleGlu: 6.572 ± 1.584
4.272IlePhe: 4.272 ± 0.334
2.629IleGly: 2.629 ± 1.237
2.3IleHis: 2.3 ± 1.006
8.216IleIle: 8.216 ± 3.538
8.216IleLys: 8.216 ± 0.682
9.53IleLeu: 9.53 ± 2.329
1.972IleMet: 1.972 ± 0.67
8.216IleAsn: 8.216 ± 1.198
3.615IlePro: 3.615 ± 0.789
4.601IleGln: 4.601 ± 0.489
3.943IleArg: 3.943 ± 1.38
10.187IleSer: 10.187 ± 0.813
5.915IleThr: 5.915 ± 1.368
4.929IleVal: 4.929 ± 1.016
0.0IleTrp: 0.0 ± 0.0
3.615IleTyr: 3.615 ± 0.763
0.0IleXaa: 0.0 ± 0.0
Lys
1.643LysAla: 1.643 ± 0.603
0.329LysCys: 0.329 ± 0.155
5.258LysAsp: 5.258 ± 0.798
5.587LysGlu: 5.587 ± 0.653
4.601LysPhe: 4.601 ± 2.335
3.286LysGly: 3.286 ± 1.504
3.286LysHis: 3.286 ± 0.768
10.845LysIle: 10.845 ± 0.757
5.587LysLys: 5.587 ± 1.762
9.201LysLeu: 9.201 ± 2.03
2.629LysMet: 2.629 ± 0.733
5.258LysAsn: 5.258 ± 0.579
2.3LysPro: 2.3 ± 1.046
1.643LysGln: 1.643 ± 0.603
4.601LysArg: 4.601 ± 1.015
6.244LysSer: 6.244 ± 0.869
2.958LysThr: 2.958 ± 0.849
3.286LysVal: 3.286 ± 0.72
1.314LysTrp: 1.314 ± 0.575
2.958LysTyr: 2.958 ± 0.803
0.0LysXaa: 0.0 ± 0.0
Leu
1.643LeuAla: 1.643 ± 0.444
2.3LeuCys: 2.3 ± 0.508
6.572LeuAsp: 6.572 ± 1.003
7.887LeuGlu: 7.887 ± 1.578
6.901LeuPhe: 6.901 ± 1.772
2.958LeuGly: 2.958 ± 0.88
3.286LeuHis: 3.286 ± 0.677
15.117LeuIle: 15.117 ± 2.27
8.544LeuLys: 8.544 ± 1.785
8.216LeuLeu: 8.216 ± 2.815
1.972LeuMet: 1.972 ± 0.578
9.53LeuAsn: 9.53 ± 1.909
2.629LeuPro: 2.629 ± 0.733
1.972LeuGln: 1.972 ± 1.048
3.943LeuArg: 3.943 ± 1.856
7.23LeuSer: 7.23 ± 2.187
4.272LeuThr: 4.272 ± 1.044
2.3LeuVal: 2.3 ± 0.272
0.657LeuTrp: 0.657 ± 0.349
6.244LeuTyr: 6.244 ± 0.752
0.0LeuXaa: 0.0 ± 0.0
Met
0.657MetAla: 0.657 ± 0.309
0.657MetCys: 0.657 ± 0.587
0.986MetAsp: 0.986 ± 0.464
1.314MetGlu: 1.314 ± 1.344
0.0MetPhe: 0.0 ± 0.0
0.986MetGly: 0.986 ± 0.534
0.0MetHis: 0.0 ± 0.0
2.3MetIle: 2.3 ± 0.594
1.643MetLys: 1.643 ± 0.773
1.314MetLeu: 1.314 ± 0.263
1.314MetMet: 1.314 ± 0.575
2.3MetAsn: 2.3 ± 1.046
0.657MetPro: 0.657 ± 0.349
0.329MetGln: 0.329 ± 0.155
0.986MetArg: 0.986 ± 0.534
2.3MetSer: 2.3 ± 1.168
2.3MetThr: 2.3 ± 0.272
0.657MetVal: 0.657 ± 0.309
0.0MetTrp: 0.0 ± 0.0
1.314MetTyr: 1.314 ± 0.263
0.0MetXaa: 0.0 ± 0.0
Asn
0.657AsnAla: 0.657 ± 0.938
0.986AsnCys: 0.986 ± 0.268
3.286AsnAsp: 3.286 ± 0.888
4.601AsnGlu: 4.601 ± 0.543
3.943AsnPhe: 3.943 ± 0.668
3.615AsnGly: 3.615 ± 1.182
0.657AsnHis: 0.657 ± 0.349
5.258AsnIle: 5.258 ± 0.798
5.915AsnLys: 5.915 ± 1.273
11.502AsnLeu: 11.502 ± 2.06
1.314AsnMet: 1.314 ± 1.174
4.272AsnAsn: 4.272 ± 0.322
1.972AsnPro: 1.972 ± 1.068
3.943AsnGln: 3.943 ± 1.331
4.272AsnArg: 4.272 ± 0.846
4.601AsnSer: 4.601 ± 1.251
4.929AsnThr: 4.929 ± 0.54
1.314AsnVal: 1.314 ± 0.619
0.986AsnTrp: 0.986 ± 0.464
2.958AsnTyr: 2.958 ± 0.803
0.0AsnXaa: 0.0 ± 0.0
Pro
0.986ProAla: 0.986 ± 1.252
0.0ProCys: 0.0 ± 0.0
1.972ProAsp: 1.972 ± 0.535
1.972ProGlu: 1.972 ± 1.068
2.629ProPhe: 2.629 ± 0.841
2.629ProGly: 2.629 ± 0.526
0.329ProHis: 0.329 ± 0.155
1.972ProIle: 1.972 ± 1.048
2.958ProLys: 2.958 ± 0.849
3.943ProLeu: 3.943 ± 0.804
0.329ProMet: 0.329 ± 0.155
3.615ProAsn: 3.615 ± 0.633
1.314ProPro: 1.314 ± 1.174
0.329ProGln: 0.329 ± 0.155
0.657ProArg: 0.657 ± 0.309
1.972ProSer: 1.972 ± 1.048
0.986ProThr: 0.986 ± 0.534
1.314ProVal: 1.314 ± 0.619
0.657ProTrp: 0.657 ± 0.349
1.314ProTyr: 1.314 ± 0.619
0.0ProXaa: 0.0 ± 0.0
Gln
0.657GlnAla: 0.657 ± 0.349
0.0GlnCys: 0.0 ± 0.0
1.972GlnAsp: 1.972 ± 0.928
3.943GlnGlu: 3.943 ± 0.441
1.643GlnPhe: 1.643 ± 0.603
1.643GlnGly: 1.643 ± 1.111
0.0GlnHis: 0.0 ± 0.0
2.958GlnIle: 2.958 ± 0.868
4.272GlnLys: 4.272 ± 1.339
2.958GlnLeu: 2.958 ± 0.376
0.329GlnMet: 0.329 ± 0.155
1.643GlnAsn: 1.643 ± 0.557
0.329GlnPro: 0.329 ± 0.155
0.986GlnGln: 0.986 ± 0.464
1.972GlnArg: 1.972 ± 0.456
2.3GlnSer: 2.3 ± 0.272
0.657GlnThr: 0.657 ± 0.309
2.3GlnVal: 2.3 ± 0.272
0.986GlnTrp: 0.986 ± 0.268
1.643GlnTyr: 1.643 ± 0.339
0.0GlnXaa: 0.0 ± 0.0
Arg
1.314ArgAla: 1.314 ± 0.619
1.314ArgCys: 1.314 ± 0.523
2.958ArgAsp: 2.958 ± 1.392
1.972ArgGlu: 1.972 ± 0.456
1.972ArgPhe: 1.972 ± 0.628
1.314ArgGly: 1.314 ± 0.523
0.986ArgHis: 0.986 ± 0.464
4.601ArgIle: 4.601 ± 2.166
2.958ArgLys: 2.958 ± 0.285
3.615ArgLeu: 3.615 ± 0.028
0.657ArgMet: 0.657 ± 0.309
2.629ArgAsn: 2.629 ± 2.217
1.972ArgPro: 1.972 ± 0.535
1.314ArgGln: 1.314 ± 0.263
1.643ArgArg: 1.643 ± 1.159
5.258ArgSer: 5.258 ± 0.345
1.314ArgThr: 1.314 ± 0.523
1.643ArgVal: 1.643 ± 0.773
0.986ArgTrp: 0.986 ± 0.464
1.314ArgTyr: 1.314 ± 0.263
0.0ArgXaa: 0.0 ± 0.0
Ser
2.629SerAla: 2.629 ± 0.526
1.643SerCys: 1.643 ± 0.444
6.572SerAsp: 6.572 ± 1.584
5.915SerGlu: 5.915 ± 1.002
3.943SerPhe: 3.943 ± 0.668
4.929SerGly: 4.929 ± 2.887
2.958SerHis: 2.958 ± 0.868
6.572SerIle: 6.572 ± 0.262
6.901SerLys: 6.901 ± 0.751
9.859SerLeu: 9.859 ± 0.515
1.643SerMet: 1.643 ± 0.904
5.915SerAsn: 5.915 ± 1.723
2.629SerPro: 2.629 ± 1.15
3.286SerGln: 3.286 ± 0.888
3.943SerArg: 3.943 ± 0.776
10.187SerSer: 10.187 ± 1.308
5.587SerThr: 5.587 ± 0.653
3.615SerVal: 3.615 ± 0.028
1.314SerTrp: 1.314 ± 0.619
4.272SerTyr: 4.272 ± 0.843
0.0SerXaa: 0.0 ± 0.0
Thr
1.314ThrAla: 1.314 ± 0.619
0.657ThrCys: 0.657 ± 0.309
2.3ThrAsp: 2.3 ± 0.726
4.929ThrGlu: 4.929 ± 0.643
2.3ThrPhe: 2.3 ± 0.726
2.3ThrGly: 2.3 ± 0.726
1.643ThrHis: 1.643 ± 0.603
4.929ThrIle: 4.929 ± 1.599
3.615ThrLys: 3.615 ± 0.577
6.244ThrLeu: 6.244 ± 1.499
1.972ThrMet: 1.972 ± 0.456
3.286ThrAsn: 3.286 ± 0.131
1.643ThrPro: 1.643 ± 0.444
0.986ThrGln: 0.986 ± 2.016
2.3ThrArg: 2.3 ± 0.591
4.929ThrSer: 4.929 ± 1.599
2.958ThrThr: 2.958 ± 0.849
1.643ThrVal: 1.643 ± 0.773
0.657ThrTrp: 0.657 ± 0.309
0.986ThrTyr: 0.986 ± 0.464
0.0ThrXaa: 0.0 ± 0.0
Val
0.986ValAla: 0.986 ± 0.268
0.986ValCys: 0.986 ± 1.407
3.615ValAsp: 3.615 ± 1.18
1.643ValGlu: 1.643 ± 0.339
0.986ValPhe: 0.986 ± 0.268
1.643ValGly: 1.643 ± 0.444
0.986ValHis: 0.986 ± 0.464
3.615ValIle: 3.615 ± 1.702
3.615ValLys: 3.615 ± 1.129
3.286ValLeu: 3.286 ± 0.677
0.329ValMet: 0.329 ± 0.672
2.958ValAsn: 2.958 ± 0.88
1.643ValPro: 1.643 ± 0.339
1.314ValGln: 1.314 ± 0.523
2.3ValArg: 2.3 ± 0.508
6.244ValSer: 6.244 ± 0.869
2.3ValThr: 2.3 ± 1.507
4.272ValVal: 4.272 ± 1.512
0.329ValTrp: 0.329 ± 0.155
0.986ValTyr: 0.986 ± 0.268
0.0ValXaa: 0.0 ± 0.0
Trp
0.329TrpAla: 0.329 ± 0.469
0.0TrpCys: 0.0 ± 0.0
0.657TrpAsp: 0.657 ± 0.309
0.986TrpGlu: 0.986 ± 0.268
0.657TrpPhe: 0.657 ± 0.309
0.986TrpGly: 0.986 ± 0.464
0.0TrpHis: 0.0 ± 0.0
0.657TrpIle: 0.657 ± 0.349
1.314TrpLys: 1.314 ± 0.263
0.329TrpLeu: 0.329 ± 0.155
0.0TrpMet: 0.0 ± 0.0
0.986TrpAsn: 0.986 ± 0.464
0.329TrpPro: 0.329 ± 0.155
0.329TrpGln: 0.329 ± 0.155
0.329TrpArg: 0.329 ± 0.155
0.986TrpSer: 0.986 ± 0.716
0.657TrpThr: 0.657 ± 0.349
1.314TrpVal: 1.314 ± 0.263
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.657TyrCys: 0.657 ± 0.349
2.3TyrAsp: 2.3 ± 2.092
1.972TyrGlu: 1.972 ± 1.068
1.314TyrPhe: 1.314 ± 0.619
1.972TyrGly: 1.972 ± 0.456
2.3TyrHis: 2.3 ± 2.092
4.272TyrIle: 4.272 ± 1.044
3.286TyrLys: 3.286 ± 0.677
4.272TyrLeu: 4.272 ± 1.044
0.657TyrMet: 0.657 ± 0.309
3.615TyrAsn: 3.615 ± 0.788
1.972TyrPro: 1.972 ± 0.928
1.314TyrGln: 1.314 ± 0.263
0.986TyrArg: 0.986 ± 0.268
4.601TyrSer: 4.601 ± 0.247
2.3TyrThr: 2.3 ± 0.591
2.629TyrVal: 2.629 ± 0.526
0.0TyrTrp: 0.0 ± 0.0
1.972TyrTyr: 1.972 ± 0.535
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3044 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski