Amino acid dipepetide frequency for Strawberry pallidosis-associated virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.41AlaAla: 2.41 ± 1.684
0.603AlaCys: 0.603 ± 0.22
2.41AlaAsp: 2.41 ± 0.525
2.008AlaGlu: 2.008 ± 0.511
2.812AlaPhe: 2.812 ± 0.588
1.808AlaGly: 1.808 ± 0.775
0.0AlaHis: 0.0 ± 0.0
3.615AlaIle: 3.615 ± 0.871
4.419AlaLys: 4.419 ± 1.003
3.013AlaLeu: 3.013 ± 1.139
1.406AlaMet: 1.406 ± 0.405
3.414AlaAsn: 3.414 ± 0.964
1.205AlaPro: 1.205 ± 0.791
1.004AlaGln: 1.004 ± 0.373
1.607AlaArg: 1.607 ± 0.614
1.607AlaSer: 1.607 ± 0.23
1.607AlaThr: 1.607 ± 0.733
1.406AlaVal: 1.406 ± 0.446
0.201AlaTrp: 0.201 ± 0.212
1.205AlaTyr: 1.205 ± 0.529
0.0AlaXaa: 0.0 ± 0.0
Cys
0.603CysAla: 0.603 ± 0.29
0.201CysCys: 0.201 ± 0.283
2.209CysAsp: 2.209 ± 0.486
1.004CysGlu: 1.004 ± 0.435
1.004CysPhe: 1.004 ± 0.407
1.004CysGly: 1.004 ± 0.442
0.402CysHis: 0.402 ± 0.245
0.803CysIle: 0.803 ± 0.306
1.004CysLys: 1.004 ± 0.344
2.209CysLeu: 2.209 ± 0.744
1.004CysMet: 1.004 ± 0.614
1.205CysAsn: 1.205 ± 0.523
0.201CysPro: 0.201 ± 0.123
0.603CysGln: 0.603 ± 0.373
0.603CysArg: 0.603 ± 0.22
1.808CysSer: 1.808 ± 0.707
1.004CysThr: 1.004 ± 0.427
1.205CysVal: 1.205 ± 0.299
0.201CysTrp: 0.201 ± 0.123
1.406CysTyr: 1.406 ± 0.481
0.0CysXaa: 0.0 ± 0.0
Asp
1.808AspAla: 1.808 ± 0.393
1.004AspCys: 1.004 ± 0.427
4.017AspAsp: 4.017 ± 0.671
3.615AspGlu: 3.615 ± 0.407
7.03AspPhe: 7.03 ± 1.047
3.615AspGly: 3.615 ± 0.443
0.803AspHis: 0.803 ± 0.609
4.619AspIle: 4.619 ± 1.105
3.615AspLys: 3.615 ± 0.456
8.435AspLeu: 8.435 ± 0.729
1.004AspMet: 1.004 ± 0.415
3.615AspAsn: 3.615 ± 0.968
0.603AspPro: 0.603 ± 0.282
0.603AspGln: 0.603 ± 0.301
2.812AspArg: 2.812 ± 0.492
5.021AspSer: 5.021 ± 0.676
3.414AspThr: 3.414 ± 1.037
5.624AspVal: 5.624 ± 0.919
0.402AspTrp: 0.402 ± 0.315
2.611AspTyr: 2.611 ± 0.475
0.0AspXaa: 0.0 ± 0.0
Glu
1.607GluAla: 1.607 ± 0.319
0.402GluCys: 0.402 ± 0.245
3.414GluAsp: 3.414 ± 0.69
4.218GluGlu: 4.218 ± 0.502
3.414GluPhe: 3.414 ± 0.701
3.414GluGly: 3.414 ± 0.544
1.004GluHis: 1.004 ± 0.288
4.017GluIle: 4.017 ± 0.876
5.021GluLys: 5.021 ± 0.56
5.824GluLeu: 5.824 ± 0.814
0.803GluMet: 0.803 ± 0.309
4.419GluAsn: 4.419 ± 0.85
1.205GluPro: 1.205 ± 0.356
1.004GluGln: 1.004 ± 0.293
2.41GluArg: 2.41 ± 0.579
4.017GluSer: 4.017 ± 0.893
3.213GluThr: 3.213 ± 0.92
6.025GluVal: 6.025 ± 0.921
0.201GluTrp: 0.201 ± 0.123
2.611GluTyr: 2.611 ± 0.738
0.0GluXaa: 0.0 ± 0.0
Phe
1.004PheAla: 1.004 ± 0.446
1.205PheCys: 1.205 ± 0.529
5.021PheAsp: 5.021 ± 0.56
2.611PheGlu: 2.611 ± 0.698
3.013PhePhe: 3.013 ± 1.072
3.414PheGly: 3.414 ± 0.427
0.603PheHis: 0.603 ± 0.523
5.222PheIle: 5.222 ± 0.514
5.021PheLys: 5.021 ± 1.168
5.021PheLeu: 5.021 ± 0.882
1.808PheMet: 1.808 ± 0.492
4.619PheAsn: 4.619 ± 0.992
1.607PhePro: 1.607 ± 0.376
2.209PheGln: 2.209 ± 0.846
2.611PheArg: 2.611 ± 0.783
8.034PheSer: 8.034 ± 1.301
3.213PheThr: 3.213 ± 0.787
2.812PheVal: 2.812 ± 0.46
0.201PheTrp: 0.201 ± 0.3
2.209PheTyr: 2.209 ± 0.326
0.0PheXaa: 0.0 ± 0.0
Gly
1.607GlyAla: 1.607 ± 0.356
1.004GlyCys: 1.004 ± 0.311
3.414GlyAsp: 3.414 ± 0.797
3.213GlyGlu: 3.213 ± 0.919
2.611GlyPhe: 2.611 ± 1.118
4.218GlyGly: 4.218 ± 0.766
0.803GlyHis: 0.803 ± 0.345
2.611GlyIle: 2.611 ± 0.231
4.82GlyLys: 4.82 ± 0.752
4.82GlyLeu: 4.82 ± 0.752
1.607GlyMet: 1.607 ± 0.583
2.812GlyAsn: 2.812 ± 0.769
0.402GlyPro: 0.402 ± 0.177
0.0GlyGln: 0.0 ± 0.0
2.611GlyArg: 2.611 ± 0.479
2.008GlySer: 2.008 ± 0.419
2.008GlyThr: 2.008 ± 0.412
3.013GlyVal: 3.013 ± 0.354
0.402GlyTrp: 0.402 ± 0.177
2.41GlyTyr: 2.41 ± 0.559
0.0GlyXaa: 0.0 ± 0.0
His
1.406HisAla: 1.406 ± 0.645
0.402HisCys: 0.402 ± 0.245
1.607HisAsp: 1.607 ± 0.376
0.402HisGlu: 0.402 ± 0.245
1.004HisPhe: 1.004 ± 0.382
0.603HisGly: 0.603 ± 0.301
0.603HisHis: 0.603 ± 0.281
1.004HisIle: 1.004 ± 0.431
1.004HisLys: 1.004 ± 0.38
1.406HisLeu: 1.406 ± 0.599
0.0HisMet: 0.0 ± 0.0
0.603HisAsn: 0.603 ± 0.251
0.603HisPro: 0.603 ± 0.209
0.0HisGln: 0.0 ± 0.0
1.205HisArg: 1.205 ± 0.567
1.607HisSer: 1.607 ± 0.519
0.803HisThr: 0.803 ± 0.388
1.205HisVal: 1.205 ± 0.47
0.0HisTrp: 0.0 ± 0.0
1.004HisTyr: 1.004 ± 0.344
0.0HisXaa: 0.0 ± 0.0
Ile
1.406IleAla: 1.406 ± 0.478
1.406IleCys: 1.406 ± 0.718
5.423IleAsp: 5.423 ± 1.251
3.615IleGlu: 3.615 ± 1.078
4.82IlePhe: 4.82 ± 0.809
2.611IleGly: 2.611 ± 0.543
1.808IleHis: 1.808 ± 0.884
5.624IleIle: 5.624 ± 1.947
5.222IleLys: 5.222 ± 0.867
6.829IleLeu: 6.829 ± 1.264
1.808IleMet: 1.808 ± 0.62
5.021IleAsn: 5.021 ± 1.607
3.816IlePro: 3.816 ± 0.71
2.008IleGln: 2.008 ± 0.558
3.414IleArg: 3.414 ± 0.552
6.226IleSer: 6.226 ± 1.351
2.611IleThr: 2.611 ± 0.447
6.226IleVal: 6.226 ± 0.986
0.201IleTrp: 0.201 ± 0.123
3.013IleTyr: 3.013 ± 0.807
0.0IleXaa: 0.0 ± 0.0
Lys
2.611LysAla: 2.611 ± 0.477
0.603LysCys: 0.603 ± 0.209
5.423LysAsp: 5.423 ± 1.224
3.816LysGlu: 3.816 ± 0.787
4.419LysPhe: 4.419 ± 1.021
3.816LysGly: 3.816 ± 0.654
1.406LysHis: 1.406 ± 0.755
6.025LysIle: 6.025 ± 1.563
7.431LysLys: 7.431 ± 1.157
8.837LysLeu: 8.837 ± 0.899
2.008LysMet: 2.008 ± 0.523
4.017LysAsn: 4.017 ± 1.009
2.41LysPro: 2.41 ± 0.813
1.607LysGln: 1.607 ± 0.394
3.213LysArg: 3.213 ± 0.832
6.025LysSer: 6.025 ± 0.92
6.025LysThr: 6.025 ± 1.293
5.222LysVal: 5.222 ± 0.679
0.402LysTrp: 0.402 ± 0.245
4.419LysTyr: 4.419 ± 0.482
0.0LysXaa: 0.0 ± 0.0
Leu
5.021LeuAla: 5.021 ± 1.057
2.008LeuCys: 2.008 ± 0.481
4.218LeuAsp: 4.218 ± 0.944
5.423LeuGlu: 5.423 ± 1.049
3.414LeuPhe: 3.414 ± 1.035
4.017LeuGly: 4.017 ± 0.911
0.603LeuHis: 0.603 ± 0.371
6.829LeuIle: 6.829 ± 1.24
9.038LeuLys: 9.038 ± 0.838
9.038LeuLeu: 9.038 ± 1.4
3.816LeuMet: 3.816 ± 0.448
6.226LeuAsn: 6.226 ± 0.615
2.812LeuPro: 2.812 ± 0.496
1.406LeuGln: 1.406 ± 0.263
5.824LeuArg: 5.824 ± 0.578
9.64LeuSer: 9.64 ± 1.239
6.427LeuThr: 6.427 ± 0.599
5.423LeuVal: 5.423 ± 0.863
0.803LeuTrp: 0.803 ± 0.636
4.017LeuTyr: 4.017 ± 0.659
0.0LeuXaa: 0.0 ± 0.0
Met
1.205MetAla: 1.205 ± 0.791
1.205MetCys: 1.205 ± 0.567
1.406MetAsp: 1.406 ± 0.401
1.004MetGlu: 1.004 ± 0.415
1.808MetPhe: 1.808 ± 0.535
0.603MetGly: 0.603 ± 0.22
0.402MetHis: 0.402 ± 0.182
1.205MetIle: 1.205 ± 0.736
2.611MetLys: 2.611 ± 0.908
1.607MetLeu: 1.607 ± 0.85
0.201MetMet: 0.201 ± 0.123
2.611MetAsn: 2.611 ± 0.907
0.603MetPro: 0.603 ± 0.226
0.803MetGln: 0.803 ± 0.61
1.004MetArg: 1.004 ± 0.336
2.008MetSer: 2.008 ± 0.747
2.209MetThr: 2.209 ± 0.518
1.004MetVal: 1.004 ± 0.285
0.0MetTrp: 0.0 ± 0.0
1.205MetTyr: 1.205 ± 0.356
0.0MetXaa: 0.0 ± 0.0
Asn
2.812AsnAla: 2.812 ± 0.933
1.004AsnCys: 1.004 ± 0.393
3.615AsnAsp: 3.615 ± 0.984
4.619AsnGlu: 4.619 ± 0.913
4.017AsnPhe: 4.017 ± 0.756
1.607AsnGly: 1.607 ± 0.373
0.402AsnHis: 0.402 ± 0.177
5.222AsnIle: 5.222 ± 0.631
5.222AsnLys: 5.222 ± 0.717
5.824AsnLeu: 5.824 ± 1.214
1.406AsnMet: 1.406 ± 0.355
4.82AsnAsn: 4.82 ± 1.234
3.615AsnPro: 3.615 ± 1.359
1.607AsnGln: 1.607 ± 0.623
2.611AsnArg: 2.611 ± 0.923
5.624AsnSer: 5.624 ± 0.984
2.812AsnThr: 2.812 ± 0.623
5.624AsnVal: 5.624 ± 0.798
0.402AsnTrp: 0.402 ± 0.307
3.013AsnTyr: 3.013 ± 0.721
0.0AsnXaa: 0.0 ± 0.0
Pro
1.406ProAla: 1.406 ± 0.47
0.803ProCys: 0.803 ± 0.447
1.607ProAsp: 1.607 ± 0.764
2.611ProGlu: 2.611 ± 1.206
2.209ProPhe: 2.209 ± 0.598
1.406ProGly: 1.406 ± 0.568
0.603ProHis: 0.603 ± 0.758
2.008ProIle: 2.008 ± 0.599
2.611ProLys: 2.611 ± 0.65
2.611ProLeu: 2.611 ± 0.687
0.603ProMet: 0.603 ± 0.343
2.812ProAsn: 2.812 ± 0.65
1.004ProPro: 1.004 ± 0.425
0.603ProGln: 0.603 ± 0.386
1.406ProArg: 1.406 ± 0.551
1.607ProSer: 1.607 ± 0.478
1.406ProThr: 1.406 ± 0.474
2.008ProVal: 2.008 ± 0.427
0.201ProTrp: 0.201 ± 0.123
1.406ProTyr: 1.406 ± 0.354
0.0ProXaa: 0.0 ± 0.0
Gln
1.406GlnAla: 1.406 ± 0.496
0.603GlnCys: 0.603 ± 0.251
1.406GlnAsp: 1.406 ± 0.412
1.808GlnGlu: 1.808 ± 0.329
2.008GlnPhe: 2.008 ± 0.5
0.603GlnGly: 0.603 ± 0.239
0.603GlnHis: 0.603 ± 0.397
1.607GlnIle: 1.607 ± 0.524
0.803GlnLys: 0.803 ± 0.309
3.013GlnLeu: 3.013 ± 1.085
1.004GlnMet: 1.004 ± 0.392
1.004GlnAsn: 1.004 ± 0.622
0.603GlnPro: 0.603 ± 0.209
0.803GlnGln: 0.803 ± 0.278
1.004GlnArg: 1.004 ± 0.299
1.004GlnSer: 1.004 ± 0.289
0.803GlnThr: 0.803 ± 0.445
1.205GlnVal: 1.205 ± 0.399
0.0GlnTrp: 0.0 ± 0.0
1.004GlnTyr: 1.004 ± 0.393
0.0GlnXaa: 0.0 ± 0.0
Arg
2.008ArgAla: 2.008 ± 0.572
1.607ArgCys: 1.607 ± 0.39
2.41ArgAsp: 2.41 ± 0.65
3.414ArgGlu: 3.414 ± 0.651
2.611ArgPhe: 2.611 ± 0.56
2.008ArgGly: 2.008 ± 0.743
1.205ArgHis: 1.205 ± 0.736
3.414ArgIle: 3.414 ± 0.648
4.017ArgLys: 4.017 ± 0.8
3.013ArgLeu: 3.013 ± 0.516
1.406ArgMet: 1.406 ± 0.493
2.611ArgAsn: 2.611 ± 0.606
1.607ArgPro: 1.607 ± 0.425
2.41ArgGln: 2.41 ± 0.469
2.611ArgArg: 2.611 ± 0.745
4.218ArgSer: 4.218 ± 0.521
2.41ArgThr: 2.41 ± 0.503
3.013ArgVal: 3.013 ± 0.964
0.603ArgTrp: 0.603 ± 0.474
1.607ArgTyr: 1.607 ± 0.383
0.0ArgXaa: 0.0 ± 0.0
Ser
3.615SerAla: 3.615 ± 0.751
1.607SerCys: 1.607 ± 0.375
5.624SerAsp: 5.624 ± 1.914
4.82SerGlu: 4.82 ± 1.173
4.619SerPhe: 4.619 ± 0.671
3.213SerGly: 3.213 ± 0.834
2.209SerHis: 2.209 ± 0.63
6.628SerIle: 6.628 ± 0.895
7.23SerLys: 7.23 ± 0.919
8.235SerLeu: 8.235 ± 1.2
1.406SerMet: 1.406 ± 0.354
6.025SerAsn: 6.025 ± 0.692
2.008SerPro: 2.008 ± 0.456
2.209SerGln: 2.209 ± 0.557
4.218SerArg: 4.218 ± 0.905
7.431SerSer: 7.431 ± 1.008
2.209SerThr: 2.209 ± 0.79
6.427SerVal: 6.427 ± 0.702
0.603SerTrp: 0.603 ± 0.368
4.218SerTyr: 4.218 ± 0.885
0.0SerXaa: 0.0 ± 0.0
Thr
2.209ThrAla: 2.209 ± 0.575
1.406ThrCys: 1.406 ± 0.548
1.808ThrAsp: 1.808 ± 0.324
3.013ThrGlu: 3.013 ± 0.897
5.423ThrPhe: 5.423 ± 1.801
2.812ThrGly: 2.812 ± 0.511
0.603ThrHis: 0.603 ± 0.368
4.017ThrIle: 4.017 ± 1.11
3.414ThrLys: 3.414 ± 1.035
6.025ThrLeu: 6.025 ± 1.127
0.603ThrMet: 0.603 ± 0.22
2.611ThrAsn: 2.611 ± 1.07
1.808ThrPro: 1.808 ± 0.392
0.803ThrGln: 0.803 ± 0.29
1.808ThrArg: 1.808 ± 0.666
4.82ThrSer: 4.82 ± 0.936
3.615ThrThr: 3.615 ± 0.562
2.812ThrVal: 2.812 ± 0.472
0.402ThrTrp: 0.402 ± 0.245
2.008ThrTyr: 2.008 ± 0.592
0.0ThrXaa: 0.0 ± 0.0
Val
1.808ValAla: 1.808 ± 0.9
1.406ValCys: 1.406 ± 0.492
5.624ValAsp: 5.624 ± 0.949
3.615ValGlu: 3.615 ± 0.487
2.611ValPhe: 2.611 ± 0.865
3.213ValGly: 3.213 ± 0.977
0.803ValHis: 0.803 ± 0.248
5.021ValIle: 5.021 ± 0.769
4.419ValLys: 4.419 ± 0.511
5.021ValLeu: 5.021 ± 1.086
1.004ValMet: 1.004 ± 0.393
5.423ValAsn: 5.423 ± 1.507
2.812ValPro: 2.812 ± 0.819
1.808ValGln: 1.808 ± 0.316
4.017ValArg: 4.017 ± 0.458
8.235ValSer: 8.235 ± 0.631
2.611ValThr: 2.611 ± 0.655
4.619ValVal: 4.619 ± 0.632
0.603ValTrp: 0.603 ± 0.332
2.812ValTyr: 2.812 ± 0.621
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.201TrpAsp: 0.201 ± 0.123
0.201TrpGlu: 0.201 ± 0.123
0.201TrpPhe: 0.201 ± 0.212
0.402TrpGly: 0.402 ± 0.264
0.402TrpHis: 0.402 ± 0.693
0.803TrpIle: 0.803 ± 0.334
0.201TrpLys: 0.201 ± 0.212
0.803TrpLeu: 0.803 ± 0.29
0.201TrpMet: 0.201 ± 0.291
0.201TrpAsn: 0.201 ± 0.212
0.201TrpPro: 0.201 ± 0.212
0.0TrpGln: 0.0 ± 0.0
0.603TrpArg: 0.603 ± 0.22
0.803TrpSer: 0.803 ± 0.409
0.201TrpThr: 0.201 ± 0.123
0.201TrpVal: 0.201 ± 0.23
0.0TrpTrp: 0.0 ± 0.0
0.201TrpTyr: 0.201 ± 0.123
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.808TyrAla: 1.808 ± 0.725
1.205TyrCys: 1.205 ± 0.563
3.414TyrAsp: 3.414 ± 0.459
3.213TyrGlu: 3.213 ± 1.255
2.41TyrPhe: 2.41 ± 0.715
2.008TyrGly: 2.008 ± 0.747
1.205TyrHis: 1.205 ± 0.529
2.812TyrIle: 2.812 ± 0.999
2.611TyrLys: 2.611 ± 0.469
4.419TyrLeu: 4.419 ± 1.093
1.406TyrMet: 1.406 ± 0.582
2.008TyrAsn: 2.008 ± 0.435
1.808TyrPro: 1.808 ± 0.661
0.803TyrGln: 0.803 ± 0.309
2.611TyrArg: 2.611 ± 0.589
2.812TyrSer: 2.812 ± 0.885
3.414TyrThr: 3.414 ± 0.713
2.41TyrVal: 2.41 ± 0.679
0.0TyrTrp: 0.0 ± 0.0
2.611TyrTyr: 2.611 ± 0.915
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 10 proteins (4980 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski