Amino acid dipepetide frequency for Jaapia argillacea MUCL 33604

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.774AlaAla: 6.774 ± 0.043	1.058AlaCys: 1.058 ± 0.013	3.617AlaAsp: 3.617 ± 0.025	4.321AlaGlu: 4.321 ± 0.031	3.092AlaPhe: 3.092 ± 0.024	4.957AlaGly: 4.957 ± 0.037	1.809AlaHis: 1.809 ± 0.018	4.024AlaIle: 4.024 ± 0.029	3.572AlaLys: 3.572 ± 0.028	7.815AlaLeu: 7.815 ± 0.038	1.753AlaMet: 1.753 ± 0.017	2.538AlaAsn: 2.538 ± 0.023	4.749AlaPro: 4.749 ± 0.035	2.883AlaGln: 2.883 ± 0.024	4.529AlaArg: 4.529 ± 0.032	7.073AlaSer: 7.073 ± 0.036	4.744AlaThr: 4.744 ± 0.029	4.967AlaVal: 4.967 ± 0.028	1.101AlaTrp: 1.101 ± 0.014	2.014AlaTyr: 2.014 ± 0.02	0.0AlaXaa: 0.0 ± 0.0
Cys	0.948CysAla: 0.948 ± 0.012	0.317CysCys: 0.317 ± 0.008	0.725CysAsp: 0.725 ± 0.012	0.654CysGlu: 0.654 ± 0.01	0.569CysPhe: 0.569 ± 0.01	0.974CysGly: 0.974 ± 0.014	0.415CysHis: 0.415 ± 0.008	0.749CysIle: 0.749 ± 0.011	0.539CysLys: 0.539 ± 0.01	1.471CysLeu: 1.471 ± 0.019	0.289CysMet: 0.289 ± 0.008	0.446CysAsn: 0.446 ± 0.009	0.918CysPro: 0.918 ± 0.014	0.544CysGln: 0.544 ± 0.011	0.89CysArg: 0.89 ± 0.014	1.114CysSer: 1.114 ± 0.016	0.795CysThr: 0.795 ± 0.012	0.88CysVal: 0.88 ± 0.012	0.274CysTrp: 0.274 ± 0.006	0.362CysTyr: 0.362 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.211AspAla: 4.211 ± 0.027	0.673AspCys: 0.673 ± 0.012	4.086AspAsp: 4.086 ± 0.043	4.301AspGlu: 4.301 ± 0.037	2.116AspPhe: 2.116 ± 0.02	4.056AspGly: 4.056 ± 0.034	1.346AspHis: 1.346 ± 0.014	2.999AspIle: 2.999 ± 0.024	2.055AspLys: 2.055 ± 0.021	5.197AspLeu: 5.197 ± 0.033	1.145AspMet: 1.145 ± 0.014	1.626AspAsn: 1.626 ± 0.018	3.521AspPro: 3.521 ± 0.027	1.677AspGln: 1.677 ± 0.016	2.89AspArg: 2.89 ± 0.022	4.022AspSer: 4.022 ± 0.03	2.73AspThr: 2.73 ± 0.024	3.974AspVal: 3.974 ± 0.025	0.906AspTrp: 0.906 ± 0.012	1.424AspTyr: 1.424 ± 0.016	0.0AspXaa: 0.0 ± 0.0
Glu	4.63GluAla: 4.63 ± 0.03	0.729GluCys: 0.729 ± 0.01	4.026GluAsp: 4.026 ± 0.031	5.48GluGlu: 5.48 ± 0.05	1.937GluPhe: 1.937 ± 0.017	4.166GluGly: 4.166 ± 0.031	1.318GluHis: 1.318 ± 0.017	2.872GluIle: 2.872 ± 0.023	3.168GluLys: 3.168 ± 0.033	5.136GluLeu: 5.136 ± 0.031	1.449GluMet: 1.449 ± 0.015	1.803GluAsn: 1.803 ± 0.014	2.611GluPro: 2.611 ± 0.021	1.931GluGln: 1.931 ± 0.018	3.892GluArg: 3.892 ± 0.033	4.106GluSer: 4.106 ± 0.027	2.94GluThr: 2.94 ± 0.023	4.017GluVal: 4.017 ± 0.025	0.965GluTrp: 0.965 ± 0.012	1.512GluTyr: 1.512 ± 0.015	0.0GluXaa: 0.0 ± 0.0
Phe	2.973PheAla: 2.973 ± 0.024	0.592PheCys: 0.592 ± 0.01	2.294PheAsp: 2.294 ± 0.019	2.067PheGlu: 2.067 ± 0.018	1.606PhePhe: 1.606 ± 0.017	2.84PheGly: 2.84 ± 0.025	1.032PheHis: 1.032 ± 0.013	1.885PheIle: 1.885 ± 0.02	1.481PheLys: 1.481 ± 0.016	3.702PheLeu: 3.702 ± 0.027	0.751PheMet: 0.751 ± 0.011	1.318PheAsn: 1.318 ± 0.014	2.238PhePro: 2.238 ± 0.017	1.313PheGln: 1.313 ± 0.015	2.041PheArg: 2.041 ± 0.017	3.219PheSer: 3.219 ± 0.025	2.289PheThr: 2.289 ± 0.018	2.569PheVal: 2.569 ± 0.023	0.611PheTrp: 0.611 ± 0.01	1.022PheTyr: 1.022 ± 0.012	0.0PheXaa: 0.0 ± 0.0
Gly	4.636GlyAla: 4.636 ± 0.033	0.98GlyCys: 0.98 ± 0.014	3.645GlyAsp: 3.645 ± 0.026	3.887GlyGlu: 3.887 ± 0.027	2.614GlyPhe: 2.614 ± 0.022	6.127GlyGly: 6.127 ± 0.055	1.706GlyHis: 1.706 ± 0.021	3.214GlyIle: 3.214 ± 0.024	3.424GlyLys: 3.424 ± 0.029	5.821GlyLeu: 5.821 ± 0.035	1.565GlyMet: 1.565 ± 0.021	2.2GlyAsn: 2.2 ± 0.019	3.276GlyPro: 3.276 ± 0.028	2.245GlyGln: 2.245 ± 0.021	4.204GlyArg: 4.204 ± 0.033	5.777GlySer: 5.777 ± 0.037	3.758GlyThr: 3.758 ± 0.029	4.614GlyVal: 4.614 ± 0.029	1.2GlyTrp: 1.2 ± 0.015	1.894GlyTyr: 1.894 ± 0.023	0.0GlyXaa: 0.0 ± 0.0
His	1.82HisAla: 1.82 ± 0.017	0.418HisCys: 0.418 ± 0.009	1.297HisAsp: 1.297 ± 0.015	1.26HisGlu: 1.26 ± 0.014	1.036HisPhe: 1.036 ± 0.014	1.646HisGly: 1.646 ± 0.017	1.059HisHis: 1.059 ± 0.017	1.412HisIle: 1.412 ± 0.015	0.876HisLys: 0.876 ± 0.013	2.908HisLeu: 2.908 ± 0.025	0.476HisMet: 0.476 ± 0.009	0.81HisAsn: 0.81 ± 0.012	2.341HisPro: 2.341 ± 0.017	1.032HisGln: 1.032 ± 0.013	1.706HisArg: 1.706 ± 0.019	2.319HisSer: 2.319 ± 0.022	1.519HisThr: 1.519 ± 0.015	1.544HisVal: 1.544 ± 0.014	0.377HisTrp: 0.377 ± 0.008	0.702HisTyr: 0.702 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	3.879IleAla: 3.879 ± 0.03	0.8IleCys: 0.8 ± 0.011	2.693IleAsp: 2.693 ± 0.021	2.596IleGlu: 2.596 ± 0.022	2.001IlePhe: 2.001 ± 0.019	2.973IleGly: 2.973 ± 0.023	1.404IleHis: 1.404 ± 0.014	2.514IleIle: 2.514 ± 0.022	1.963IleLys: 1.963 ± 0.017	4.903IleLeu: 4.903 ± 0.032	0.921IleMet: 0.921 ± 0.011	1.588IleAsn: 1.588 ± 0.017	3.612IlePro: 3.612 ± 0.023	1.888IleGln: 1.888 ± 0.017	2.93IleArg: 2.93 ± 0.024	4.18IleSer: 4.18 ± 0.028	2.903IleThr: 2.903 ± 0.024	3.32IleVal: 3.32 ± 0.027	0.797IleTrp: 0.797 ± 0.012	1.337IleTyr: 1.337 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	3.792LysAla: 3.792 ± 0.03	0.548LysCys: 0.548 ± 0.011	2.397LysAsp: 2.397 ± 0.024	3.13LysGlu: 3.13 ± 0.031	1.428LysPhe: 1.428 ± 0.016	3.05LysGly: 3.05 ± 0.027	1.071LysHis: 1.071 ± 0.013	1.973LysIle: 1.973 ± 0.019	2.919LysLys: 2.919 ± 0.037	3.9LysLeu: 3.9 ± 0.029	0.936LysMet: 0.936 ± 0.013	1.328LysAsn: 1.328 ± 0.015	2.559LysPro: 2.559 ± 0.023	1.494LysGln: 1.494 ± 0.016	3.189LysArg: 3.189 ± 0.027	3.313LysSer: 3.313 ± 0.023	2.408LysThr: 2.408 ± 0.023	2.837LysVal: 2.837 ± 0.023	0.705LysTrp: 0.705 ± 0.011	1.172LysTyr: 1.172 ± 0.015	0.0LysXaa: 0.0 ± 0.0
Leu	7.897LeuAla: 7.897 ± 0.04	1.392LeuCys: 1.392 ± 0.018	5.226LeuAsp: 5.226 ± 0.028	5.528LeuGlu: 5.528 ± 0.034	3.446LeuPhe: 3.446 ± 0.023	5.899LeuGly: 5.899 ± 0.034	2.679LeuHis: 2.679 ± 0.026	4.138LeuIle: 4.138 ± 0.026	4.057LeuLys: 4.057 ± 0.028	9.015LeuLeu: 9.015 ± 0.046	1.766LeuMet: 1.766 ± 0.017	3.093LeuAsn: 3.093 ± 0.026	6.734LeuPro: 6.734 ± 0.036	3.713LeuGln: 3.713 ± 0.028	6.132LeuArg: 6.132 ± 0.036	8.643LeuSer: 8.643 ± 0.043	5.53LeuThr: 5.53 ± 0.033	6.056LeuVal: 6.056 ± 0.033	1.324LeuTrp: 1.324 ± 0.017	2.36LeuTyr: 2.36 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	1.835MetAla: 1.835 ± 0.016	0.264MetCys: 0.264 ± 0.006	1.267MetAsp: 1.267 ± 0.015	1.291MetGlu: 1.291 ± 0.015	0.777MetPhe: 0.777 ± 0.011	1.408MetGly: 1.408 ± 0.017	0.486MetHis: 0.486 ± 0.008	0.954MetIle: 0.954 ± 0.012	1.018MetLys: 1.018 ± 0.012	1.748MetLeu: 1.748 ± 0.015	0.54MetMet: 0.54 ± 0.009	0.739MetAsn: 0.739 ± 0.012	1.197MetPro: 1.197 ± 0.016	0.712MetGln: 0.712 ± 0.011	1.199MetArg: 1.199 ± 0.016	1.935MetSer: 1.935 ± 0.017	1.264MetThr: 1.264 ± 0.015	1.312MetVal: 1.312 ± 0.014	0.3MetTrp: 0.3 ± 0.006	0.492MetTyr: 0.492 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	2.638AsnAla: 2.638 ± 0.018	0.45AsnCys: 0.45 ± 0.01	1.65AsnAsp: 1.65 ± 0.016	1.63AsnGlu: 1.63 ± 0.015	1.242AsnPhe: 1.242 ± 0.014	2.517AsnGly: 2.517 ± 0.023	0.9AsnHis: 0.9 ± 0.013	1.88AsnIle: 1.88 ± 0.016	1.24AsnLys: 1.24 ± 0.013	3.35AsnLeu: 3.35 ± 0.028	0.687AsnMet: 0.687 ± 0.01	1.159AsnAsn: 1.159 ± 0.015	2.559AsnPro: 2.559 ± 0.019	1.183AsnGln: 1.183 ± 0.014	1.737AsnArg: 1.737 ± 0.018	2.569AsnSer: 2.569 ± 0.023	1.969AsnThr: 1.969 ± 0.019	2.272AsnVal: 2.272 ± 0.02	0.515AsnTrp: 0.515 ± 0.009	0.87AsnTyr: 0.87 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	4.836ProAla: 4.836 ± 0.037	0.652ProCys: 0.652 ± 0.013	3.229ProAsp: 3.229 ± 0.027	3.455ProGlu: 3.455 ± 0.03	2.412ProPhe: 2.412 ± 0.021	3.755ProGly: 3.755 ± 0.029	1.854ProHis: 1.854 ± 0.019	3.108ProIle: 3.108 ± 0.026	2.509ProLys: 2.509 ± 0.021	5.774ProLeu: 5.774 ± 0.033	1.101ProMet: 1.101 ± 0.014	2.472ProAsn: 2.472 ± 0.022	7.459ProPro: 7.459 ± 0.073	2.507ProGln: 2.507 ± 0.023	3.716ProArg: 3.716 ± 0.031	8.394ProSer: 8.394 ± 0.054	5.015ProThr: 5.015 ± 0.032	3.778ProVal: 3.778 ± 0.026	0.746ProTrp: 0.746 ± 0.012	1.664ProTyr: 1.664 ± 0.017	0.0ProXaa: 0.0 ± 0.0
Gln	3.007GlnAla: 3.007 ± 0.025	0.521GlnCys: 0.521 ± 0.01	1.879GlnAsp: 1.879 ± 0.018	2.067GlnGlu: 2.067 ± 0.02	1.278GlnPhe: 1.278 ± 0.013	2.204GlnGly: 2.204 ± 0.02	1.024GlnHis: 1.024 ± 0.012	1.771GlnIle: 1.771 ± 0.017	1.547GlnLys: 1.547 ± 0.016	3.407GlnLeu: 3.407 ± 0.024	0.807GlnMet: 0.807 ± 0.012	1.241GlnAsn: 1.241 ± 0.013	2.52GlnPro: 2.52 ± 0.026	1.825GlnGln: 1.825 ± 0.034	2.231GlnArg: 2.231 ± 0.021	3.087GlnSer: 3.087 ± 0.023	2.17GlnThr: 2.17 ± 0.018	2.238GlnVal: 2.238 ± 0.02	0.557GlnTrp: 0.557 ± 0.01	1.041GlnTyr: 1.041 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	4.428ArgAla: 4.428 ± 0.032	0.892ArgCys: 0.892 ± 0.013	3.324ArgAsp: 3.324 ± 0.027	3.804ArgGlu: 3.804 ± 0.035	2.263ArgPhe: 2.263 ± 0.02	3.728ArgGly: 3.728 ± 0.027	1.672ArgHis: 1.672 ± 0.019	2.953ArgIle: 2.953 ± 0.024	3.215ArgLys: 3.215 ± 0.025	5.795ArgLeu: 5.795 ± 0.038	1.357ArgMet: 1.357 ± 0.015	1.979ArgAsn: 1.979 ± 0.018	3.669ArgPro: 3.669 ± 0.031	2.259ArgGln: 2.259 ± 0.021	5.171ArgArg: 5.171 ± 0.039	5.214ArgSer: 5.214 ± 0.039	3.393ArgThr: 3.393 ± 0.025	3.745ArgVal: 3.745 ± 0.025	1.015ArgTrp: 1.015 ± 0.012	1.566ArgTyr: 1.566 ± 0.015	0.0ArgXaa: 0.0 ± 0.0
Ser	6.38SerAla: 6.38 ± 0.034	1.09SerCys: 1.09 ± 0.015	4.418SerAsp: 4.418 ± 0.031	4.074SerGlu: 4.074 ± 0.026	3.332SerPhe: 3.332 ± 0.025	5.703SerGly: 5.703 ± 0.035	2.479SerHis: 2.479 ± 0.021	4.306SerIle: 4.306 ± 0.028	3.464SerLys: 3.464 ± 0.027	8.724SerLeu: 8.724 ± 0.043	1.721SerMet: 1.721 ± 0.019	2.921SerAsn: 2.921 ± 0.026	7.109SerPro: 7.109 ± 0.056	3.353SerGln: 3.353 ± 0.027	5.431SerArg: 5.431 ± 0.037	10.791SerSer: 10.791 ± 0.064	6.376SerThr: 6.376 ± 0.038	5.04SerVal: 5.04 ± 0.03	1.18SerTrp: 1.18 ± 0.015	2.115SerTyr: 2.115 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	4.439ThrAla: 4.439 ± 0.028	0.856ThrCys: 0.856 ± 0.012	2.639ThrAsp: 2.639 ± 0.02	2.647ThrGlu: 2.647 ± 0.019	2.504ThrPhe: 2.504 ± 0.021	3.716ThrGly: 3.716 ± 0.027	1.582ThrHis: 1.582 ± 0.018	3.243ThrIle: 3.243 ± 0.024	2.406ThrLys: 2.406 ± 0.021	6.066ThrLeu: 6.066 ± 0.037	1.156ThrMet: 1.156 ± 0.012	2.039ThrAsn: 2.039 ± 0.021	5.034ThrPro: 5.034 ± 0.036	2.058ThrGln: 2.058 ± 0.019	3.367ThrArg: 3.367 ± 0.025	6.143ThrSer: 6.143 ± 0.035	4.423ThrThr: 4.423 ± 0.037	3.631ThrVal: 3.631 ± 0.028	0.846ThrTrp: 0.846 ± 0.012	1.562ThrTyr: 1.562 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	5.213ValAla: 5.213 ± 0.031	0.937ValCys: 0.937 ± 0.011	4.027ValAsp: 4.027 ± 0.026	4.18ValGlu: 4.18 ± 0.026	2.501ValPhe: 2.501 ± 0.024	4.333ValGly: 4.333 ± 0.03	1.582ValHis: 1.582 ± 0.017	3.104ValIle: 3.104 ± 0.023	2.908ValLys: 2.908 ± 0.026	5.989ValLeu: 5.989 ± 0.032	1.354ValMet: 1.354 ± 0.015	2.119ValAsn: 2.119 ± 0.021	3.949ValPro: 3.949 ± 0.028	2.313ValGln: 2.313 ± 0.018	3.579ValArg: 3.579 ± 0.025	4.923ValSer: 4.923 ± 0.031	3.634ValThr: 3.634 ± 0.027	4.903ValVal: 4.903 ± 0.036	1.01ValTrp: 1.01 ± 0.015	1.715ValTyr: 1.715 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	1.08TrpAla: 1.08 ± 0.014	0.253TrpCys: 0.253 ± 0.006	0.965TrpAsp: 0.965 ± 0.014	0.953TrpGlu: 0.953 ± 0.013	0.594TrpPhe: 0.594 ± 0.009	0.924TrpGly: 0.924 ± 0.013	0.367TrpHis: 0.367 ± 0.008	0.775TrpIle: 0.775 ± 0.012	0.82TrpLys: 0.82 ± 0.013	1.345TrpLeu: 1.345 ± 0.016	0.424TrpMet: 0.424 ± 0.009	0.612TrpAsn: 0.612 ± 0.011	0.651TrpPro: 0.651 ± 0.011	0.494TrpGln: 0.494 ± 0.008	1.036TrpArg: 1.036 ± 0.014	1.191TrpSer: 1.191 ± 0.013	0.916TrpThr: 0.916 ± 0.012	0.982TrpVal: 0.982 ± 0.012	0.338TrpTrp: 0.338 ± 0.008	0.434TrpTyr: 0.434 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.974TyrAla: 1.974 ± 0.018	0.449TyrCys: 0.449 ± 0.008	1.553TyrAsp: 1.553 ± 0.017	1.362TyrGlu: 1.362 ± 0.014	1.093TyrPhe: 1.093 ± 0.015	1.812TyrGly: 1.812 ± 0.02	0.773TyrHis: 0.773 ± 0.012	1.328TyrIle: 1.328 ± 0.013	0.969TyrLys: 0.969 ± 0.013	2.563TyrLeu: 2.563 ± 0.02	0.539TyrMet: 0.539 ± 0.01	0.986TyrAsn: 0.986 ± 0.015	1.73TyrPro: 1.73 ± 0.021	1.003TyrGln: 1.003 ± 0.013	1.572TyrArg: 1.572 ± 0.017	1.994TyrSer: 1.994 ± 0.019	1.582TyrThr: 1.582 ± 0.018	1.591TyrVal: 1.591 ± 0.017	0.388TyrTrp: 0.388 ± 0.008	0.813TyrTyr: 0.813 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 16341 proteins (6436100 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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