Amino acid dipepetide frequency for Phaius virus X

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.669AlaAla: 7.669 ± 3.314
1.534AlaCys: 1.534 ± 1.355
1.022AlaAsp: 1.022 ± 0.786
3.067AlaGlu: 3.067 ± 1.354
3.579AlaPhe: 3.579 ± 1.758
5.112AlaGly: 5.112 ± 1.361
4.09AlaHis: 4.09 ± 1.418
8.18AlaIle: 8.18 ± 2.313
6.135AlaLys: 6.135 ± 1.526
11.247AlaLeu: 11.247 ± 3.67
5.112AlaMet: 5.112 ± 2.129
5.112AlaAsn: 5.112 ± 2.074
5.112AlaPro: 5.112 ± 1.413
1.534AlaGln: 1.534 ± 0.927
3.579AlaArg: 3.579 ± 0.989
5.112AlaSer: 5.112 ± 1.37
7.157AlaThr: 7.157 ± 1.363
3.067AlaVal: 3.067 ± 1.446
0.511AlaTrp: 0.511 ± 0.84
4.601AlaTyr: 4.601 ± 1.196
0.0AlaXaa: 0.0 ± 0.0
Cys
1.534CysAla: 1.534 ± 0.84
0.0CysCys: 0.0 ± 0.0
1.022CysAsp: 1.022 ± 0.786
2.556CysGlu: 2.556 ± 3.039
0.0CysPhe: 0.0 ± 0.0
2.045CysGly: 2.045 ± 0.997
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
2.045CysLeu: 2.045 ± 0.997
0.0CysMet: 0.0 ± 0.0
1.022CysAsn: 1.022 ± 0.71
2.045CysPro: 2.045 ± 2.485
1.534CysGln: 1.534 ± 0.723
1.022CysArg: 1.022 ± 0.71
1.022CysSer: 1.022 ± 0.71
1.022CysThr: 1.022 ± 1.571
1.022CysVal: 1.022 ± 2.499
0.0CysTrp: 0.0 ± 0.0
0.511CysTyr: 0.511 ± 1.249
0.0CysXaa: 0.0 ± 0.0
Asp
4.601AspAla: 4.601 ± 1.318
0.0AspCys: 0.0 ± 0.0
1.534AspAsp: 1.534 ± 0.84
3.067AspGlu: 3.067 ± 1.447
2.556AspPhe: 2.556 ± 1.359
2.556AspGly: 2.556 ± 2.664
1.022AspHis: 1.022 ± 0.56
3.579AspIle: 3.579 ± 1.31
4.09AspLys: 4.09 ± 2.296
3.579AspLeu: 3.579 ± 0.768
0.511AspMet: 0.511 ± 0.28
2.045AspAsn: 2.045 ± 1.06
4.601AspPro: 4.601 ± 3.256
1.534AspGln: 1.534 ± 0.84
1.534AspArg: 1.534 ± 0.84
3.579AspSer: 3.579 ± 1.961
1.022AspThr: 1.022 ± 0.56
2.556AspVal: 2.556 ± 0.897
1.022AspTrp: 1.022 ± 0.56
1.534AspTyr: 1.534 ± 1.054
0.0AspXaa: 0.0 ± 0.0
Glu
7.157GluAla: 7.157 ± 1.958
0.511GluCys: 0.511 ± 0.28
3.579GluAsp: 3.579 ± 1.31
4.601GluGlu: 4.601 ± 1.196
2.045GluPhe: 2.045 ± 1.42
2.045GluGly: 2.045 ± 1.421
1.022GluHis: 1.022 ± 2.06
1.534GluIle: 1.534 ± 0.927
2.045GluLys: 2.045 ± 1.12
8.691GluLeu: 8.691 ± 2.244
0.0GluMet: 0.0 ± 0.0
1.022GluAsn: 1.022 ± 0.56
4.601GluPro: 4.601 ± 1.283
3.067GluGln: 3.067 ± 0.954
1.534GluArg: 1.534 ± 0.677
3.067GluSer: 3.067 ± 1.124
1.534GluThr: 1.534 ± 0.677
5.624GluVal: 5.624 ± 2.397
1.022GluTrp: 1.022 ± 0.56
3.579GluTyr: 3.579 ± 1.42
0.0GluXaa: 0.0 ± 0.0
Phe
3.067PheAla: 3.067 ± 1.271
2.045PheCys: 2.045 ± 0.755
2.556PheAsp: 2.556 ± 1.671
1.534PheGlu: 1.534 ± 0.84
1.534PhePhe: 1.534 ± 1.53
2.045PheGly: 2.045 ± 1.972
1.534PheHis: 1.534 ± 0.723
2.045PheIle: 2.045 ± 0.997
1.022PheLys: 1.022 ± 0.56
5.112PheLeu: 5.112 ± 1.84
0.511PheMet: 0.511 ± 0.28
1.534PheAsn: 1.534 ± 0.723
2.556PhePro: 2.556 ± 1.484
3.067PheGln: 3.067 ± 1.42
2.045PheArg: 2.045 ± 0.765
2.045PheSer: 2.045 ± 1.12
4.09PheThr: 4.09 ± 2.026
2.045PheVal: 2.045 ± 0.976
0.0PheTrp: 0.0 ± 0.0
1.022PheTyr: 1.022 ± 0.56
0.0PheXaa: 0.0 ± 0.0
Gly
5.112GlyAla: 5.112 ± 2.542
2.045GlyCys: 2.045 ± 1.573
3.067GlyAsp: 3.067 ± 1.021
3.579GlyGlu: 3.579 ± 0.768
2.045GlyPhe: 2.045 ± 0.755
3.579GlyGly: 3.579 ± 1.042
1.534GlyHis: 1.534 ± 0.84
1.534GlyIle: 1.534 ± 0.677
4.09GlyLys: 4.09 ± 1.531
5.624GlyLeu: 5.624 ± 4.448
1.534GlyMet: 1.534 ± 1.117
1.534GlyAsn: 1.534 ± 0.84
2.556GlyPro: 2.556 ± 1.177
0.511GlyGln: 0.511 ± 0.28
2.045GlyArg: 2.045 ± 0.976
3.579GlySer: 3.579 ± 2.593
2.045GlyThr: 2.045 ± 2.038
4.601GlyVal: 4.601 ± 3.45
1.022GlyTrp: 1.022 ± 0.56
2.045GlyTyr: 2.045 ± 0.997
0.0GlyXaa: 0.0 ± 0.0
His
2.045HisAla: 2.045 ± 0.997
0.511HisCys: 0.511 ± 1.03
1.022HisAsp: 1.022 ± 0.56
1.022HisGlu: 1.022 ± 0.939
2.045HisPhe: 2.045 ± 1.12
2.556HisGly: 2.556 ± 1.136
2.556HisHis: 2.556 ± 1.136
2.045HisIle: 2.045 ± 1.12
0.0HisLys: 0.0 ± 0.0
3.579HisLeu: 3.579 ± 0.957
0.0HisMet: 0.0 ± 0.0
0.511HisAsn: 0.511 ± 0.28
4.09HisPro: 4.09 ± 0.794
1.022HisGln: 1.022 ± 0.56
4.09HisArg: 4.09 ± 1.531
2.045HisSer: 2.045 ± 0.976
2.556HisThr: 2.556 ± 2.481
2.045HisVal: 2.045 ± 1.06
0.511HisTrp: 0.511 ± 0.28
1.534HisTyr: 1.534 ± 1.169
0.0HisXaa: 0.0 ± 0.0
Ile
5.112IleAla: 5.112 ± 1.413
0.511IleCys: 0.511 ± 0.28
1.022IleAsp: 1.022 ± 0.939
2.045IleGlu: 2.045 ± 1.12
2.045IlePhe: 2.045 ± 1.12
3.579IleGly: 3.579 ± 1.894
2.045IleHis: 2.045 ± 1.06
2.556IleIle: 2.556 ± 0.857
2.045IleLys: 2.045 ± 1.12
5.112IleLeu: 5.112 ± 1.163
2.556IleMet: 2.556 ± 1.401
3.067IleAsn: 3.067 ± 0.954
3.067IlePro: 3.067 ± 1.124
3.067IleGln: 3.067 ± 0.9
2.556IleArg: 2.556 ± 0.894
2.556IleSer: 2.556 ± 1.021
4.09IleThr: 4.09 ± 1.343
2.045IleVal: 2.045 ± 1.572
0.0IleTrp: 0.0 ± 0.0
1.534IleTyr: 1.534 ± 3.748
0.0IleXaa: 0.0 ± 0.0
Lys
5.624LysAla: 5.624 ± 3.081
0.0LysCys: 0.0 ± 0.0
2.556LysAsp: 2.556 ± 1.401
5.112LysGlu: 5.112 ± 2.063
2.556LysPhe: 2.556 ± 2.509
1.534LysGly: 1.534 ± 1.117
2.556LysHis: 2.556 ± 1.401
2.045LysIle: 2.045 ± 0.755
2.556LysLys: 2.556 ± 1.401
8.18LysLeu: 8.18 ± 2.201
0.511LysMet: 0.511 ± 0.28
1.022LysAsn: 1.022 ± 0.56
2.556LysPro: 2.556 ± 0.897
0.511LysGln: 0.511 ± 0.28
2.045LysArg: 2.045 ± 1.06
3.579LysSer: 3.579 ± 0.935
5.112LysThr: 5.112 ± 1.795
1.022LysVal: 1.022 ± 0.56
0.0LysTrp: 0.0 ± 0.0
2.556LysTyr: 2.556 ± 1.671
0.0LysXaa: 0.0 ± 0.0
Leu
6.646LeuAla: 6.646 ± 3.94
1.534LeuCys: 1.534 ± 0.723
6.135LeuAsp: 6.135 ± 0.99
3.579LeuGlu: 3.579 ± 0.876
4.09LeuPhe: 4.09 ± 1.761
6.135LeuGly: 6.135 ± 3.088
4.09LeuHis: 4.09 ± 1.084
5.624LeuIle: 5.624 ± 1.454
9.202LeuLys: 9.202 ± 2.392
8.691LeuLeu: 8.691 ± 3.537
1.022LeuMet: 1.022 ± 0.539
2.556LeuAsn: 2.556 ± 0.897
9.714LeuPro: 9.714 ± 1.89
3.579LeuGln: 3.579 ± 1.922
3.579LeuArg: 3.579 ± 0.876
4.09LeuSer: 4.09 ± 1.622
8.18LeuThr: 8.18 ± 1.672
4.09LeuVal: 4.09 ± 2.647
1.022LeuTrp: 1.022 ± 1.122
3.579LeuTyr: 3.579 ± 0.935
0.0LeuXaa: 0.0 ± 0.0
Met
4.09MetAla: 4.09 ± 1.141
0.511MetCys: 0.511 ± 0.84
1.534MetAsp: 1.534 ± 0.677
1.022MetGlu: 1.022 ± 1.37
0.511MetPhe: 0.511 ± 0.28
1.534MetGly: 1.534 ± 0.84
0.511MetHis: 0.511 ± 0.28
1.022MetIle: 1.022 ± 0.56
2.045MetLys: 2.045 ± 1.12
3.067MetLeu: 3.067 ± 1.681
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
2.556MetPro: 2.556 ± 1.136
2.045MetGln: 2.045 ± 0.755
1.022MetArg: 1.022 ± 0.56
1.022MetSer: 1.022 ± 0.56
0.0MetThr: 0.0 ± 0.0
1.022MetVal: 1.022 ± 0.71
0.0MetTrp: 0.0 ± 0.0
0.511MetTyr: 0.511 ± 0.28
0.0MetXaa: 0.0 ± 0.0
Asn
5.112AsnAla: 5.112 ± 1.556
1.022AsnCys: 1.022 ± 0.939
1.534AsnAsp: 1.534 ± 0.84
1.022AsnGlu: 1.022 ± 0.56
2.045AsnPhe: 2.045 ± 0.765
1.022AsnGly: 1.022 ± 0.71
0.511AsnHis: 0.511 ± 0.28
2.556AsnIle: 2.556 ± 2.055
1.022AsnLys: 1.022 ± 0.786
1.022AsnLeu: 1.022 ± 0.786
1.534AsnMet: 1.534 ± 1.154
2.556AsnAsn: 2.556 ± 2.159
3.067AsnPro: 3.067 ± 0.9
3.579AsnGln: 3.579 ± 1.359
1.534AsnArg: 1.534 ± 0.677
1.022AsnSer: 1.022 ± 0.56
3.067AsnThr: 3.067 ± 1.124
2.045AsnVal: 2.045 ± 1.857
0.511AsnTrp: 0.511 ± 0.84
2.556AsnTyr: 2.556 ± 0.916
0.0AsnXaa: 0.0 ± 0.0
Pro
6.646ProAla: 6.646 ± 1.21
1.534ProCys: 1.534 ± 2.262
5.624ProAsp: 5.624 ± 1.345
6.135ProGlu: 6.135 ± 2.174
3.067ProPhe: 3.067 ± 1.544
2.556ProGly: 2.556 ± 0.916
1.534ProHis: 1.534 ± 2.358
5.112ProIle: 5.112 ± 2.063
3.579ProLys: 3.579 ± 1.961
3.067ProLeu: 3.067 ± 4.199
1.022ProMet: 1.022 ± 0.946
3.067ProAsn: 3.067 ± 2.541
3.579ProPro: 3.579 ± 1.758
2.045ProGln: 2.045 ± 1.12
4.09ProArg: 4.09 ± 2.407
3.579ProSer: 3.579 ± 1.042
4.601ProThr: 4.601 ± 1.249
2.556ProVal: 2.556 ± 0.897
1.022ProTrp: 1.022 ± 0.56
2.556ProTyr: 2.556 ± 1.492
0.0ProXaa: 0.0 ± 0.0
Gln
5.624GlnAla: 5.624 ± 1.467
1.022GlnCys: 1.022 ± 0.939
2.045GlnAsp: 2.045 ± 1.007
3.579GlnGlu: 3.579 ± 1.359
0.511GlnPhe: 0.511 ± 0.28
3.067GlnGly: 3.067 ± 1.854
1.534GlnHis: 1.534 ± 1.152
1.022GlnIle: 1.022 ± 0.56
1.534GlnLys: 1.534 ± 0.723
4.601GlnLeu: 4.601 ± 1.804
1.534GlnMet: 1.534 ± 0.84
1.534GlnAsn: 1.534 ± 0.84
2.556GlnPro: 2.556 ± 1.136
2.556GlnGln: 2.556 ± 0.905
1.022GlnArg: 1.022 ± 0.939
1.534GlnSer: 1.534 ± 0.84
2.556GlnThr: 2.556 ± 0.916
2.556GlnVal: 2.556 ± 1.563
1.022GlnTrp: 1.022 ± 0.71
1.022GlnTyr: 1.022 ± 0.56
0.0GlnXaa: 0.0 ± 0.0
Arg
3.067ArgAla: 3.067 ± 1.021
0.511ArgCys: 0.511 ± 1.249
3.067ArgAsp: 3.067 ± 1.271
3.067ArgGlu: 3.067 ± 0.9
1.534ArgPhe: 1.534 ± 1.152
2.045ArgGly: 2.045 ± 1.166
2.556ArgHis: 2.556 ± 1.484
1.534ArgIle: 1.534 ± 1.361
1.022ArgLys: 1.022 ± 0.56
3.067ArgLeu: 3.067 ± 1.681
0.0ArgMet: 0.0 ± 0.0
4.601ArgAsn: 4.601 ± 1.295
1.534ArgPro: 1.534 ± 1.355
3.067ArgGln: 3.067 ± 0.884
3.579ArgArg: 3.579 ± 0.957
1.534ArgSer: 1.534 ± 2.727
3.067ArgThr: 3.067 ± 1.087
4.601ArgVal: 4.601 ± 1.655
0.511ArgTrp: 0.511 ± 0.28
4.09ArgTyr: 4.09 ± 1.329
0.0ArgXaa: 0.0 ± 0.0
Ser
2.045SerAla: 2.045 ± 2.515
1.022SerCys: 1.022 ± 1.854
3.579SerAsp: 3.579 ± 0.876
2.556SerGlu: 2.556 ± 2.233
2.045SerPhe: 2.045 ± 1.06
4.09SerGly: 4.09 ± 2.005
2.556SerHis: 2.556 ± 1.021
2.045SerIle: 2.045 ± 1.166
3.067SerLys: 3.067 ± 1.124
4.601SerLeu: 4.601 ± 1.487
2.556SerMet: 2.556 ± 0.88
2.556SerAsn: 2.556 ± 1.134
2.045SerPro: 2.045 ± 0.997
3.067SerGln: 3.067 ± 1.124
3.067SerArg: 3.067 ± 0.82
4.601SerSer: 4.601 ± 1.697
4.09SerThr: 4.09 ± 1.013
3.579SerVal: 3.579 ± 1.31
1.534SerTrp: 1.534 ± 0.927
2.045SerTyr: 2.045 ± 0.997
0.0SerXaa: 0.0 ± 0.0
Thr
4.601ThrAla: 4.601 ± 1.901
2.045ThrCys: 2.045 ± 1.166
2.045ThrAsp: 2.045 ± 2.038
3.579ThrGlu: 3.579 ± 1.359
5.112ThrPhe: 5.112 ± 2.177
3.579ThrGly: 3.579 ± 1.66
3.067ThrHis: 3.067 ± 1.087
3.067ThrIle: 3.067 ± 1.461
2.556ThrLys: 2.556 ± 1.776
6.135ThrLeu: 6.135 ± 1.028
1.022ThrMet: 1.022 ± 0.56
3.579ThrAsn: 3.579 ± 1.397
6.646ThrPro: 6.646 ± 2.215
1.534ThrGln: 1.534 ± 0.84
4.09ThrArg: 4.09 ± 3.224
4.601ThrSer: 4.601 ± 1.271
5.624ThrThr: 5.624 ± 3.296
5.624ThrVal: 5.624 ± 1.928
0.511ThrTrp: 0.511 ± 0.28
1.022ThrTyr: 1.022 ± 0.56
0.0ThrXaa: 0.0 ± 0.0
Val
4.601ValAla: 4.601 ± 5.237
0.511ValCys: 0.511 ± 0.84
1.534ValAsp: 1.534 ± 1.701
5.624ValGlu: 5.624 ± 1.557
1.534ValPhe: 1.534 ± 1.054
2.045ValGly: 2.045 ± 1.06
1.022ValHis: 1.022 ± 0.71
3.579ValIle: 3.579 ± 1.484
4.09ValLys: 4.09 ± 1.551
6.135ValLeu: 6.135 ± 1.626
2.045ValMet: 2.045 ± 1.12
0.511ValAsn: 0.511 ± 0.28
2.045ValPro: 2.045 ± 1.166
2.556ValGln: 2.556 ± 1.401
3.579ValArg: 3.579 ± 0.768
4.09ValSer: 4.09 ± 2.005
5.624ValThr: 5.624 ± 2.894
4.09ValVal: 4.09 ± 2.199
0.511ValTrp: 0.511 ± 0.84
1.022ValTyr: 1.022 ± 0.56
0.0ValXaa: 0.0 ± 0.0
Trp
1.534TrpAla: 1.534 ± 2.174
0.511TrpCys: 0.511 ± 0.28
0.511TrpAsp: 0.511 ± 0.28
0.511TrpGlu: 0.511 ± 0.28
0.511TrpPhe: 0.511 ± 0.28
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.022TrpLys: 1.022 ± 0.56
1.022TrpLeu: 1.022 ± 0.939
1.534TrpMet: 1.534 ± 0.677
0.511TrpAsn: 0.511 ± 0.84
0.511TrpPro: 0.511 ± 0.28
1.022TrpGln: 1.022 ± 0.56
0.511TrpArg: 0.511 ± 0.28
0.511TrpSer: 0.511 ± 0.28
0.511TrpThr: 0.511 ± 1.249
1.022TrpVal: 1.022 ± 0.56
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
6.646TyrAla: 6.646 ± 1.922
1.022TyrCys: 1.022 ± 0.56
1.534TyrAsp: 1.534 ± 0.84
1.022TyrGlu: 1.022 ± 0.71
2.045TyrPhe: 2.045 ± 1.12
2.556TyrGly: 2.556 ± 1.492
2.045TyrHis: 2.045 ± 0.997
1.534TyrIle: 1.534 ± 1.701
0.511TyrLys: 0.511 ± 0.28
2.556TyrLeu: 2.556 ± 1.136
0.511TyrMet: 0.511 ± 0.28
0.0TyrAsn: 0.0 ± 0.0
2.045TyrPro: 2.045 ± 1.844
1.534TyrGln: 1.534 ± 0.677
1.534TyrArg: 1.534 ± 1.361
3.579TyrSer: 3.579 ± 1.485
4.09TyrThr: 4.09 ± 1.716
1.534TyrVal: 1.534 ± 0.84
1.022TyrTrp: 1.022 ± 1.122
1.534TyrTyr: 1.534 ± 1.361
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1957 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski