Amino acid dipepetide frequency for Gabek Forest virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.207AlaAla: 5.207 ± 1.592
1.488AlaCys: 1.488 ± 0.359
1.736AlaAsp: 1.736 ± 0.641
4.215AlaGlu: 4.215 ± 0.842
2.727AlaPhe: 2.727 ± 0.853
3.471AlaGly: 3.471 ± 0.405
2.232AlaHis: 2.232 ± 0.479
5.207AlaIle: 5.207 ± 1.69
2.975AlaLys: 2.975 ± 1.09
4.711AlaLeu: 4.711 ± 1.492
2.727AlaMet: 2.727 ± 0.4
0.744AlaAsn: 0.744 ± 0.328
1.488AlaPro: 1.488 ± 0.433
2.975AlaGln: 2.975 ± 1.319
1.984AlaArg: 1.984 ± 0.548
5.951AlaSer: 5.951 ± 0.646
2.727AlaThr: 2.727 ± 0.863
3.719AlaVal: 3.719 ± 0.744
0.248AlaTrp: 0.248 ± 0.584
1.488AlaTyr: 1.488 ± 0.52
0.0AlaXaa: 0.0 ± 0.0
Cys
0.496CysAla: 0.496 ± 0.305
0.496CysCys: 0.496 ± 0.305
0.496CysAsp: 0.496 ± 0.148
0.992CysGlu: 0.992 ± 0.609
1.984CysPhe: 1.984 ± 0.341
0.744CysGly: 0.744 ± 0.216
0.744CysHis: 0.744 ± 0.626
1.24CysIle: 1.24 ± 0.465
1.984CysLys: 1.984 ± 0.791
3.967CysLeu: 3.967 ± 1.109
0.248CysMet: 0.248 ± 0.152
1.984CysAsn: 1.984 ± 0.489
0.744CysPro: 0.744 ± 0.626
0.496CysGln: 0.496 ± 0.148
1.24CysArg: 1.24 ± 0.43
3.223CysSer: 3.223 ± 0.626
2.232CysThr: 2.232 ± 0.985
1.736CysVal: 1.736 ± 1.288
0.0CysTrp: 0.0 ± 0.0
0.496CysTyr: 0.496 ± 0.148
0.0CysXaa: 0.0 ± 0.0
Asp
2.727AspAla: 2.727 ± 0.973
0.744AspCys: 0.744 ± 0.328
4.463AspAsp: 4.463 ± 0.518
4.463AspGlu: 4.463 ± 1.086
1.736AspPhe: 1.736 ± 0.413
2.975AspGly: 2.975 ± 0.502
1.488AspHis: 1.488 ± 0.861
2.727AspIle: 2.727 ± 0.896
2.48AspLys: 2.48 ± 0.767
4.463AspLeu: 4.463 ± 1.563
1.24AspMet: 1.24 ± 0.338
2.232AspAsn: 2.232 ± 0.649
3.223AspPro: 3.223 ± 0.872
0.744AspGln: 0.744 ± 0.483
2.232AspArg: 2.232 ± 0.547
3.471AspSer: 3.471 ± 1.358
2.975AspThr: 2.975 ± 0.473
4.463AspVal: 4.463 ± 0.925
1.488AspTrp: 1.488 ± 0.359
1.24AspTyr: 1.24 ± 0.747
0.0AspXaa: 0.0 ± 0.0
Glu
5.703GluAla: 5.703 ± 0.653
2.232GluCys: 2.232 ± 0.618
2.727GluAsp: 2.727 ± 1.117
9.422GluGlu: 9.422 ± 1.169
4.215GluPhe: 4.215 ± 1.557
5.207GluGly: 5.207 ± 0.365
0.992GluHis: 0.992 ± 0.431
5.703GluIle: 5.703 ± 1.254
3.719GluLys: 3.719 ± 0.605
6.447GluLeu: 6.447 ± 1.499
2.232GluMet: 2.232 ± 0.393
3.223GluAsn: 3.223 ± 1.256
1.24GluPro: 1.24 ± 0.418
1.488GluGln: 1.488 ± 0.657
2.727GluArg: 2.727 ± 0.896
5.703GluSer: 5.703 ± 0.829
3.967GluThr: 3.967 ± 1.097
4.959GluVal: 4.959 ± 1.431
0.496GluTrp: 0.496 ± 0.148
1.488GluTyr: 1.488 ± 0.705
0.0GluXaa: 0.0 ± 0.0
Phe
3.967PheAla: 3.967 ± 1.49
1.24PheCys: 1.24 ± 0.338
3.967PheAsp: 3.967 ± 2.276
1.736PheGlu: 1.736 ± 0.386
1.736PhePhe: 1.736 ± 0.54
3.223PheGly: 3.223 ± 1.132
0.248PheHis: 0.248 ± 0.152
1.24PheIle: 1.24 ± 0.43
2.727PheLys: 2.727 ± 0.762
4.463PheLeu: 4.463 ± 1.095
1.984PheMet: 1.984 ± 0.341
1.984PheAsn: 1.984 ± 0.593
2.232PhePro: 2.232 ± 0.771
0.496PheGln: 0.496 ± 0.535
2.727PheArg: 2.727 ± 1.26
3.223PheSer: 3.223 ± 0.468
2.975PheThr: 2.975 ± 0.812
3.223PheVal: 3.223 ± 0.736
0.248PheTrp: 0.248 ± 0.152
0.248PheTyr: 0.248 ± 0.587
0.0PheXaa: 0.0 ± 0.0
Gly
3.223GlyAla: 3.223 ± 0.982
0.744GlyCys: 0.744 ± 0.328
3.719GlyAsp: 3.719 ± 0.723
5.207GlyGlu: 5.207 ± 0.746
4.463GlyPhe: 4.463 ± 0.816
4.463GlyGly: 4.463 ± 0.781
0.992GlyHis: 0.992 ± 0.344
2.48GlyIle: 2.48 ± 0.552
3.967GlyLys: 3.967 ± 0.664
5.455GlyLeu: 5.455 ± 0.361
1.24GlyMet: 1.24 ± 0.455
2.975GlyAsn: 2.975 ± 2.173
2.232GlyPro: 2.232 ± 0.618
1.736GlyGln: 1.736 ± 0.346
2.727GlyArg: 2.727 ± 1.015
6.695GlySer: 6.695 ± 1.588
2.232GlyThr: 2.232 ± 0.447
4.711GlyVal: 4.711 ± 1.414
1.488GlyTrp: 1.488 ± 0.465
1.24GlyTyr: 1.24 ± 0.465
0.0GlyXaa: 0.0 ± 0.0
His
0.992HisAla: 0.992 ± 0.53
0.496HisCys: 0.496 ± 0.305
0.992HisAsp: 0.992 ± 0.835
0.744HisGlu: 0.744 ± 0.328
1.488HisPhe: 1.488 ± 0.359
1.736HisGly: 1.736 ± 0.554
0.496HisHis: 0.496 ± 0.148
1.24HisIle: 1.24 ± 0.485
1.488HisLys: 1.488 ± 0.458
1.24HisLeu: 1.24 ± 0.735
0.744HisMet: 0.744 ± 0.888
0.992HisAsn: 0.992 ± 0.535
1.736HisPro: 1.736 ± 0.904
0.744HisGln: 0.744 ± 0.578
1.984HisArg: 1.984 ± 0.547
1.488HisSer: 1.488 ± 0.465
1.984HisThr: 1.984 ± 0.396
1.488HisVal: 1.488 ± 0.381
0.0HisTrp: 0.0 ± 0.0
0.992HisTyr: 0.992 ± 0.53
0.0HisXaa: 0.0 ± 0.0
Ile
2.727IleAla: 2.727 ± 0.583
0.992IleCys: 0.992 ± 0.488
4.215IleAsp: 4.215 ± 1.077
6.447IleGlu: 6.447 ± 1.479
1.736IlePhe: 1.736 ± 0.781
3.967IleGly: 3.967 ± 1.583
0.992IleHis: 0.992 ± 0.297
6.943IleIle: 6.943 ± 1.018
3.967IleLys: 3.967 ± 1.192
4.959IleLeu: 4.959 ± 0.897
3.223IleMet: 3.223 ± 1.354
3.223IleAsn: 3.223 ± 1.254
2.232IlePro: 2.232 ± 0.649
1.736IleGln: 1.736 ± 0.554
5.951IleArg: 5.951 ± 0.972
5.951IleSer: 5.951 ± 1.154
3.719IleThr: 3.719 ± 1.395
3.967IleVal: 3.967 ± 0.229
0.496IleTrp: 0.496 ± 0.305
1.736IleTyr: 1.736 ± 0.641
0.0IleXaa: 0.0 ± 0.0
Lys
3.967LysAla: 3.967 ± 0.978
2.48LysCys: 2.48 ± 1.184
2.727LysAsp: 2.727 ± 0.724
4.463LysGlu: 4.463 ± 1.815
2.975LysPhe: 2.975 ± 1.181
3.719LysGly: 3.719 ± 0.582
0.992LysHis: 0.992 ± 0.297
4.463LysIle: 4.463 ± 0.521
5.455LysLys: 5.455 ± 0.41
5.207LysLeu: 5.207 ± 2.912
3.719LysMet: 3.719 ± 1.312
2.727LysAsn: 2.727 ± 0.49
3.223LysPro: 3.223 ± 0.942
1.736LysGln: 1.736 ± 0.346
2.975LysArg: 2.975 ± 0.812
4.711LysSer: 4.711 ± 0.744
2.727LysThr: 2.727 ± 1.099
5.455LysVal: 5.455 ± 1.488
0.992LysTrp: 0.992 ± 0.554
2.727LysTyr: 2.727 ± 0.361
0.0LysXaa: 0.0 ± 0.0
Leu
5.455LeuAla: 5.455 ± 0.61
1.488LeuCys: 1.488 ± 0.632
3.967LeuAsp: 3.967 ± 1.16
5.455LeuGlu: 5.455 ± 1.273
3.719LeuPhe: 3.719 ± 1.129
4.959LeuGly: 4.959 ± 0.473
1.984LeuHis: 1.984 ± 0.548
5.455LeuIle: 5.455 ± 1.845
7.439LeuLys: 7.439 ± 1.497
7.191LeuLeu: 7.191 ± 2.672
2.48LeuMet: 2.48 ± 1.006
3.471LeuAsn: 3.471 ± 0.405
1.984LeuPro: 1.984 ± 0.718
3.471LeuGln: 3.471 ± 0.843
5.703LeuArg: 5.703 ± 0.499
9.67LeuSer: 9.67 ± 0.929
4.959LeuThr: 4.959 ± 1.643
3.223LeuVal: 3.223 ± 0.841
0.496LeuTrp: 0.496 ± 0.148
2.727LeuTyr: 2.727 ± 0.863
0.0LeuXaa: 0.0 ± 0.0
Met
0.992MetAla: 0.992 ± 0.431
0.744MetCys: 0.744 ± 0.457
1.984MetAsp: 1.984 ± 0.718
1.736MetGlu: 1.736 ± 0.913
0.496MetPhe: 0.496 ± 0.305
1.736MetGly: 1.736 ± 0.554
1.488MetHis: 1.488 ± 0.705
1.736MetIle: 1.736 ± 0.61
1.984MetLys: 1.984 ± 0.548
2.232MetLeu: 2.232 ± 0.649
1.488MetMet: 1.488 ± 0.861
1.736MetAsn: 1.736 ± 0.54
0.496MetPro: 0.496 ± 0.417
1.24MetGln: 1.24 ± 0.622
1.736MetArg: 1.736 ± 0.641
4.711MetSer: 4.711 ± 1.053
2.232MetThr: 2.232 ± 0.33
1.488MetVal: 1.488 ± 0.381
0.248MetTrp: 0.248 ± 0.587
0.744MetTyr: 0.744 ± 0.328
0.0MetXaa: 0.0 ± 0.0
Asn
2.232AsnAla: 2.232 ± 1.719
1.24AsnCys: 1.24 ± 0.935
1.984AsnAsp: 1.984 ± 0.489
2.232AsnGlu: 2.232 ± 0.752
2.48AsnPhe: 2.48 ± 1.142
1.24AsnGly: 1.24 ± 0.338
1.488AsnHis: 1.488 ± 0.381
2.975AsnIle: 2.975 ± 0.473
3.223AsnLys: 3.223 ± 1.107
3.719AsnLeu: 3.719 ± 1.129
0.496AsnMet: 0.496 ± 0.305
0.992AsnAsn: 0.992 ± 0.535
3.223AsnPro: 3.223 ± 0.5
1.488AsnGln: 1.488 ± 0.657
1.736AsnArg: 1.736 ± 0.666
5.455AsnSer: 5.455 ± 0.853
1.736AsnThr: 1.736 ± 0.857
2.232AsnVal: 2.232 ± 0.595
0.0AsnTrp: 0.0 ± 0.0
0.744AsnTyr: 0.744 ± 0.483
0.0AsnXaa: 0.0 ± 0.0
Pro
2.232ProAla: 2.232 ± 0.389
0.496ProCys: 0.496 ± 0.417
1.984ProAsp: 1.984 ± 0.648
4.215ProGlu: 4.215 ± 1.421
1.736ProPhe: 1.736 ± 0.666
4.711ProGly: 4.711 ± 0.365
0.744ProHis: 0.744 ± 0.216
2.48ProIle: 2.48 ± 0.767
2.48ProLys: 2.48 ± 0.609
2.232ProLeu: 2.232 ± 0.595
0.992ProMet: 0.992 ± 0.488
1.736ProAsn: 1.736 ± 0.54
0.744ProPro: 0.744 ± 0.328
1.24ProGln: 1.24 ± 0.338
2.48ProArg: 2.48 ± 0.942
2.975ProSer: 2.975 ± 0.925
1.488ProThr: 1.488 ± 0.985
2.232ProVal: 2.232 ± 0.479
0.744ProTrp: 0.744 ± 0.457
0.744ProTyr: 0.744 ± 0.457
0.0ProXaa: 0.0 ± 0.0
Gln
1.24GlnAla: 1.24 ± 0.43
0.992GlnCys: 0.992 ± 0.431
0.992GlnAsp: 0.992 ± 0.344
1.24GlnGlu: 1.24 ± 0.485
0.248GlnPhe: 0.248 ± 0.209
2.232GlnGly: 2.232 ± 0.77
0.744GlnHis: 0.744 ± 0.216
3.719GlnIle: 3.719 ± 1.12
3.967GlnLys: 3.967 ± 1.743
1.488GlnLeu: 1.488 ± 0.445
0.496GlnMet: 0.496 ± 0.305
1.488GlnAsn: 1.488 ± 0.632
1.24GlnPro: 1.24 ± 0.479
1.24GlnGln: 1.24 ± 0.485
1.488GlnArg: 1.488 ± 0.445
1.736GlnSer: 1.736 ± 0.913
2.232GlnThr: 2.232 ± 0.389
0.496GlnVal: 0.496 ± 0.148
0.248GlnTrp: 0.248 ± 0.209
1.24GlnTyr: 1.24 ± 0.411
0.0GlnXaa: 0.0 ± 0.0
Arg
3.471ArgAla: 3.471 ± 0.511
1.488ArgCys: 1.488 ± 0.445
3.719ArgAsp: 3.719 ± 0.667
5.703ArgGlu: 5.703 ± 1.502
1.488ArgPhe: 1.488 ± 0.52
4.215ArgGly: 4.215 ± 1.049
0.248ArgHis: 0.248 ± 0.152
3.223ArgIle: 3.223 ± 0.738
3.223ArgLys: 3.223 ± 0.626
5.207ArgLeu: 5.207 ± 1.037
1.984ArgMet: 1.984 ± 0.931
2.48ArgAsn: 2.48 ± 0.472
2.232ArgPro: 2.232 ± 0.415
1.736ArgGln: 1.736 ± 0.41
2.48ArgArg: 2.48 ± 0.552
4.215ArgSer: 4.215 ± 1.129
2.48ArgThr: 2.48 ± 0.608
3.223ArgVal: 3.223 ± 0.844
1.24ArgTrp: 1.24 ± 0.622
1.736ArgTyr: 1.736 ± 0.476
0.0ArgXaa: 0.0 ± 0.0
Ser
4.959SerAla: 4.959 ± 0.944
2.48SerCys: 2.48 ± 1.542
3.967SerAsp: 3.967 ± 1.933
5.951SerGlu: 5.951 ± 1.232
4.711SerPhe: 4.711 ± 1.535
6.447SerGly: 6.447 ± 1.299
2.232SerHis: 2.232 ± 0.618
7.191SerIle: 7.191 ± 1.2
6.199SerLys: 6.199 ± 1.117
8.926SerLeu: 8.926 ± 2.657
1.984SerMet: 1.984 ± 0.791
3.471SerAsn: 3.471 ± 0.755
4.215SerPro: 4.215 ± 0.688
0.992SerGln: 0.992 ± 0.609
5.951SerArg: 5.951 ± 1.633
7.191SerSer: 7.191 ± 2.375
6.695SerThr: 6.695 ± 2.272
2.727SerVal: 2.727 ± 0.896
2.232SerTrp: 2.232 ± 0.479
1.984SerTyr: 1.984 ± 0.648
0.0SerXaa: 0.0 ± 0.0
Thr
2.727ThrAla: 2.727 ± 1.143
2.232ThrCys: 2.232 ± 0.94
2.727ThrAsp: 2.727 ± 0.583
4.959ThrGlu: 4.959 ± 1.354
0.496ThrPhe: 0.496 ± 0.148
3.223ThrGly: 3.223 ± 1.324
1.736ThrHis: 1.736 ± 1.192
3.719ThrIle: 3.719 ± 1.191
3.967ThrLys: 3.967 ± 0.876
6.943ThrLeu: 6.943 ± 1.072
0.744ThrMet: 0.744 ± 0.523
0.992ThrAsn: 0.992 ± 0.297
2.975ThrPro: 2.975 ± 0.427
1.488ThrGln: 1.488 ± 0.433
3.719ThrArg: 3.719 ± 0.117
5.703ThrSer: 5.703 ± 1.088
3.967ThrThr: 3.967 ± 1.192
2.975ThrVal: 2.975 ± 1.298
0.248ThrTrp: 0.248 ± 0.152
1.984ThrTyr: 1.984 ± 0.912
0.0ThrXaa: 0.0 ± 0.0
Val
3.967ValAla: 3.967 ± 0.844
2.727ValCys: 2.727 ± 1.119
3.471ValAsp: 3.471 ± 0.579
3.223ValGlu: 3.223 ± 1.132
3.967ValPhe: 3.967 ± 0.899
1.736ValGly: 1.736 ± 0.346
2.48ValHis: 2.48 ± 1.219
4.463ValIle: 4.463 ± 1.223
4.215ValLys: 4.215 ± 1.89
3.967ValLeu: 3.967 ± 0.923
2.232ValMet: 2.232 ± 0.827
2.232ValAsn: 2.232 ± 0.842
0.992ValPro: 0.992 ± 0.344
2.232ValGln: 2.232 ± 0.77
3.719ValArg: 3.719 ± 0.591
5.207ValSer: 5.207 ± 0.668
3.223ValThr: 3.223 ± 0.917
4.463ValVal: 4.463 ± 0.61
0.0ValTrp: 0.0 ± 0.0
0.744ValTyr: 0.744 ± 0.216
0.0ValXaa: 0.0 ± 0.0
Trp
0.744TrpAla: 0.744 ± 0.216
0.248TrpCys: 0.248 ± 0.587
0.744TrpAsp: 0.744 ± 0.216
0.496TrpGlu: 0.496 ± 0.148
0.248TrpPhe: 0.248 ± 0.152
0.992TrpGly: 0.992 ± 0.431
0.0TrpHis: 0.0 ± 0.0
0.992TrpIle: 0.992 ± 0.297
0.0TrpLys: 0.0 ± 0.0
0.744TrpLeu: 0.744 ± 0.216
0.496TrpMet: 0.496 ± 0.305
0.744TrpAsn: 0.744 ± 0.216
0.496TrpPro: 0.496 ± 0.535
0.744TrpGln: 0.744 ± 0.578
0.496TrpArg: 0.496 ± 0.148
0.744TrpSer: 0.744 ± 0.493
1.24TrpThr: 1.24 ± 0.747
1.24TrpVal: 1.24 ± 0.411
0.248TrpTrp: 0.248 ± 0.152
0.248TrpTyr: 0.248 ± 0.152
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.992TyrAla: 0.992 ± 0.701
0.496TyrCys: 0.496 ± 0.148
0.992TyrAsp: 0.992 ± 1.069
1.24TyrGlu: 1.24 ± 0.338
1.24TyrPhe: 1.24 ± 0.485
0.992TyrGly: 0.992 ± 0.344
0.744TyrHis: 0.744 ± 0.578
1.984TyrIle: 1.984 ± 0.547
1.984TyrLys: 1.984 ± 0.718
1.736TyrLeu: 1.736 ± 0.61
0.248TyrMet: 0.248 ± 0.152
1.488TyrAsn: 1.488 ± 0.445
1.736TyrPro: 1.736 ± 0.61
0.744TyrGln: 0.744 ± 0.483
1.736TyrArg: 1.736 ± 0.413
2.48TyrSer: 2.48 ± 1.045
1.736TyrThr: 1.736 ± 0.54
1.24TyrVal: 1.24 ± 0.761
0.744TyrTrp: 0.744 ± 0.328
0.992TyrTyr: 0.992 ± 0.456
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (4034 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski