Amino acid dipepetide frequency for Neurachne minor latent virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.77AlaAla: 9.77 ± 3.021
2.094AlaCys: 2.094 ± 0.266
6.281AlaAsp: 6.281 ± 0.537
5.583AlaGlu: 5.583 ± 3.824
3.489AlaPhe: 3.489 ± 1.782
13.259AlaGly: 13.259 ± 1.239
2.094AlaHis: 2.094 ± 0.266
1.396AlaIle: 1.396 ± 0.713
4.885AlaLys: 4.885 ± 0.176
8.374AlaLeu: 8.374 ± 0.271
1.396AlaMet: 1.396 ± 0.713
2.094AlaAsn: 2.094 ± 0.266
0.0AlaPro: 0.0 ± 0.0
4.885AlaGln: 4.885 ± 1.511
5.583AlaArg: 5.583 ± 1.154
4.187AlaSer: 4.187 ± 1.867
3.489AlaThr: 3.489 ± 0.447
4.885AlaVal: 4.885 ± 0.176
2.094AlaTrp: 2.094 ± 0.266
1.396AlaTyr: 1.396 ± 0.713
0.0AlaXaa: 0.0 ± 0.0
Cys
2.791CysAla: 2.791 ± 0.09
0.0CysCys: 0.0 ± 0.0
0.698CysAsp: 0.698 ± 0.356
0.0CysGlu: 0.0 ± 0.0
0.698CysPhe: 0.698 ± 0.356
0.698CysGly: 0.698 ± 0.356
1.396CysHis: 1.396 ± 0.622
1.396CysIle: 1.396 ± 0.622
0.698CysLys: 0.698 ± 0.356
1.396CysLeu: 1.396 ± 0.713
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.396CysPro: 1.396 ± 0.622
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.698CysSer: 0.698 ± 0.356
3.489CysThr: 3.489 ± 0.888
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.791AspAla: 2.791 ± 1.425
0.0AspCys: 0.0 ± 0.0
8.374AspAsp: 8.374 ± 0.271
9.072AspGlu: 9.072 ± 0.708
0.698AspPhe: 0.698 ± 0.356
2.094AspGly: 2.094 ± 1.069
2.094AspHis: 2.094 ± 0.266
6.978AspIle: 6.978 ± 0.893
2.094AspLys: 2.094 ± 0.266
5.583AspLeu: 5.583 ± 1.154
1.396AspMet: 1.396 ± 0.29
4.187AspAsn: 4.187 ± 0.803
4.187AspPro: 4.187 ± 1.867
3.489AspGln: 3.489 ± 0.888
3.489AspArg: 3.489 ± 0.447
2.791AspSer: 2.791 ± 0.09
2.791AspThr: 2.791 ± 1.245
2.094AspVal: 2.094 ± 1.069
0.698AspTrp: 0.698 ± 0.356
0.698AspTyr: 0.698 ± 0.356
0.0AspXaa: 0.0 ± 0.0
Glu
9.072GluAla: 9.072 ± 3.378
0.0GluCys: 0.0 ± 0.0
5.583GluAsp: 5.583 ± 2.489
9.072GluGlu: 9.072 ± 3.378
0.698GluPhe: 0.698 ± 0.356
2.791GluGly: 2.791 ± 1.245
3.489GluHis: 3.489 ± 0.888
1.396GluIle: 1.396 ± 0.622
6.978GluLys: 6.978 ± 1.777
11.165GluLeu: 11.165 ± 0.361
0.698GluMet: 0.698 ± 0.356
2.094GluAsn: 2.094 ± 0.266
0.698GluPro: 0.698 ± 0.356
4.187GluGln: 4.187 ± 0.532
4.885GluArg: 4.885 ± 0.176
3.489GluSer: 3.489 ± 0.888
4.885GluThr: 4.885 ± 2.846
5.583GluVal: 5.583 ± 1.154
0.698GluTrp: 0.698 ± 0.356
0.698GluTyr: 0.698 ± 0.979
0.0GluXaa: 0.0 ± 0.0
Phe
0.698PheAla: 0.698 ± 0.356
0.0PheCys: 0.0 ± 0.0
2.791PheAsp: 2.791 ± 0.09
0.698PheGlu: 0.698 ± 0.356
2.094PhePhe: 2.094 ± 1.069
4.885PheGly: 4.885 ± 0.176
0.698PheHis: 0.698 ± 0.356
3.489PheIle: 3.489 ± 0.447
1.396PheLys: 1.396 ± 0.622
2.791PheLeu: 2.791 ± 1.425
0.698PheMet: 0.698 ± 0.356
3.489PheAsn: 3.489 ± 0.447
0.698PhePro: 0.698 ± 0.356
1.396PheGln: 1.396 ± 0.713
6.281PheArg: 6.281 ± 0.798
2.094PheSer: 2.094 ± 1.069
2.094PheThr: 2.094 ± 0.266
2.791PheVal: 2.791 ± 1.425
0.698PheTrp: 0.698 ± 0.356
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.489GlyAla: 3.489 ± 0.888
0.698GlyCys: 0.698 ± 0.356
2.791GlyAsp: 2.791 ± 0.09
4.885GlyGlu: 4.885 ± 1.511
0.698GlyPhe: 0.698 ± 0.356
3.489GlyGly: 3.489 ± 1.782
0.0GlyHis: 0.0 ± 0.0
3.489GlyIle: 3.489 ± 1.782
3.489GlyLys: 3.489 ± 0.888
3.489GlyLeu: 3.489 ± 1.782
0.698GlyMet: 0.698 ± 0.6
2.094GlyAsn: 2.094 ± 1.069
1.396GlyPro: 1.396 ± 0.713
2.094GlyGln: 2.094 ± 0.266
8.374GlyArg: 8.374 ± 0.271
3.489GlySer: 3.489 ± 0.447
2.791GlyThr: 2.791 ± 1.245
3.489GlyVal: 3.489 ± 0.447
1.396GlyTrp: 1.396 ± 0.713
2.094GlyTyr: 2.094 ± 0.266
0.0GlyXaa: 0.0 ± 0.0
His
0.698HisAla: 0.698 ± 0.356
0.0HisCys: 0.0 ± 0.0
1.396HisAsp: 1.396 ± 0.713
1.396HisGlu: 1.396 ± 0.622
0.698HisPhe: 0.698 ± 0.356
0.0HisGly: 0.0 ± 0.0
0.698HisHis: 0.698 ± 0.356
2.094HisIle: 2.094 ± 0.266
0.698HisLys: 0.698 ± 0.356
2.094HisLeu: 2.094 ± 0.266
0.698HisMet: 0.698 ± 0.356
2.094HisAsn: 2.094 ± 0.266
0.0HisPro: 0.0 ± 0.0
2.094HisGln: 2.094 ± 0.266
2.094HisArg: 2.094 ± 0.266
1.396HisSer: 1.396 ± 0.622
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.698HisTrp: 0.698 ± 0.356
2.094HisTyr: 2.094 ± 1.069
0.0HisXaa: 0.0 ± 0.0
Ile
5.583IleAla: 5.583 ± 2.489
1.396IleCys: 1.396 ± 0.713
3.489IleAsp: 3.489 ± 1.782
2.791IleGlu: 2.791 ± 0.09
0.698IlePhe: 0.698 ± 0.356
1.396IleGly: 1.396 ± 0.713
0.698IleHis: 0.698 ± 0.356
4.885IleIle: 4.885 ± 1.159
4.187IleLys: 4.187 ± 0.532
2.094IleLeu: 2.094 ± 1.069
0.698IleMet: 0.698 ± 0.356
3.489IleAsn: 3.489 ± 0.447
2.791IlePro: 2.791 ± 0.09
2.791IleGln: 2.791 ± 0.09
4.885IleArg: 4.885 ± 0.176
3.489IleSer: 3.489 ± 0.447
2.094IleThr: 2.094 ± 0.266
3.489IleVal: 3.489 ± 1.782
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
4.187LysAla: 4.187 ± 0.532
2.094LysCys: 2.094 ± 0.266
1.396LysAsp: 1.396 ± 0.622
5.583LysGlu: 5.583 ± 1.154
6.281LysPhe: 6.281 ± 0.537
2.791LysGly: 2.791 ± 1.245
2.094LysHis: 2.094 ± 0.266
4.885LysIle: 4.885 ± 0.176
8.374LysLys: 8.374 ± 3.734
6.281LysLeu: 6.281 ± 1.872
2.094LysMet: 2.094 ± 0.266
3.489LysAsn: 3.489 ± 0.447
2.094LysPro: 2.094 ± 1.069
0.698LysGln: 0.698 ± 0.979
0.698LysArg: 0.698 ± 0.979
6.281LysSer: 6.281 ± 0.798
1.396LysThr: 1.396 ± 0.713
1.396LysVal: 1.396 ± 0.713
2.094LysTrp: 2.094 ± 0.266
1.396LysTyr: 1.396 ± 0.713
0.0LysXaa: 0.0 ± 0.0
Leu
6.281LeuAla: 6.281 ± 1.872
0.698LeuCys: 0.698 ± 0.356
5.583LeuAsp: 5.583 ± 0.181
6.978LeuGlu: 6.978 ± 0.442
4.187LeuPhe: 4.187 ± 0.532
4.187LeuGly: 4.187 ± 2.138
1.396LeuHis: 1.396 ± 0.713
3.489LeuIle: 3.489 ± 0.447
4.885LeuLys: 4.885 ± 2.494
10.468LeuLeu: 10.468 ± 5.345
2.094LeuMet: 2.094 ± 0.266
2.094LeuAsn: 2.094 ± 1.069
3.489LeuPro: 3.489 ± 1.782
3.489LeuGln: 3.489 ± 0.888
7.676LeuArg: 7.676 ± 2.585
1.396LeuSer: 1.396 ± 0.713
7.676LeuThr: 7.676 ± 1.42
4.885LeuVal: 4.885 ± 0.176
3.489LeuTrp: 3.489 ± 0.447
2.094LeuTyr: 2.094 ± 1.069
0.0LeuXaa: 0.0 ± 0.0
Met
1.396MetAla: 1.396 ± 0.713
0.0MetCys: 0.0 ± 0.0
1.396MetAsp: 1.396 ± 0.713
1.396MetGlu: 1.396 ± 0.713
0.698MetPhe: 0.698 ± 0.356
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.698MetIle: 0.698 ± 0.356
1.396MetLys: 1.396 ± 0.713
2.094MetLeu: 2.094 ± 1.069
2.094MetMet: 2.094 ± 1.069
1.396MetAsn: 1.396 ± 0.622
1.396MetPro: 1.396 ± 0.622
0.0MetGln: 0.0 ± 0.0
0.698MetArg: 0.698 ± 0.356
0.0MetSer: 0.0 ± 0.0
1.396MetThr: 1.396 ± 0.713
1.396MetVal: 1.396 ± 0.713
0.0MetTrp: 0.0 ± 0.0
1.396MetTyr: 1.396 ± 0.622
0.0MetXaa: 0.0 ± 0.0
Asn
4.187AsnAla: 4.187 ± 0.803
0.0AsnCys: 0.0 ± 0.0
4.187AsnAsp: 4.187 ± 0.532
3.489AsnGlu: 3.489 ± 0.888
2.094AsnPhe: 2.094 ± 1.069
3.489AsnGly: 3.489 ± 0.447
1.396AsnHis: 1.396 ± 0.713
2.791AsnIle: 2.791 ± 0.09
2.094AsnLys: 2.094 ± 0.266
3.489AsnLeu: 3.489 ± 2.223
0.0AsnMet: 0.0 ± 0.0
1.396AsnAsn: 1.396 ± 0.713
2.791AsnPro: 2.791 ± 1.425
0.0AsnGln: 0.0 ± 0.0
3.489AsnArg: 3.489 ± 0.888
0.698AsnSer: 0.698 ± 0.356
0.0AsnThr: 0.0 ± 0.0
7.676AsnVal: 7.676 ± 1.42
0.698AsnTrp: 0.698 ± 0.356
0.698AsnTyr: 0.698 ± 0.356
0.0AsnXaa: 0.0 ± 0.0
Pro
4.885ProAla: 4.885 ± 0.176
0.698ProCys: 0.698 ± 0.356
2.094ProAsp: 2.094 ± 0.266
2.791ProGlu: 2.791 ± 1.245
2.094ProPhe: 2.094 ± 1.069
0.698ProGly: 0.698 ± 0.356
0.0ProHis: 0.0 ± 0.0
1.396ProIle: 1.396 ± 0.713
3.489ProLys: 3.489 ± 0.447
6.978ProLeu: 6.978 ± 2.228
0.0ProMet: 0.0 ± 0.0
0.698ProAsn: 0.698 ± 0.356
4.885ProPro: 4.885 ± 0.176
0.0ProGln: 0.0 ± 0.0
2.094ProArg: 2.094 ± 0.266
1.396ProSer: 1.396 ± 0.713
1.396ProThr: 1.396 ± 0.622
5.583ProVal: 5.583 ± 1.154
0.0ProTrp: 0.0 ± 0.0
0.698ProTyr: 0.698 ± 0.356
0.0ProXaa: 0.0 ± 0.0
Gln
5.583GlnAla: 5.583 ± 0.181
2.791GlnCys: 2.791 ± 1.245
0.698GlnAsp: 0.698 ± 0.356
3.489GlnGlu: 3.489 ± 0.888
2.094GlnPhe: 2.094 ± 1.069
0.0GlnGly: 0.0 ± 0.0
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
2.094GlnLys: 2.094 ± 0.266
2.094GlnLeu: 2.094 ± 1.069
0.698GlnMet: 0.698 ± 0.356
1.396GlnAsn: 1.396 ± 0.622
0.0GlnPro: 0.0 ± 0.0
1.396GlnGln: 1.396 ± 0.622
3.489GlnArg: 3.489 ± 2.223
0.698GlnSer: 0.698 ± 0.979
2.094GlnThr: 2.094 ± 0.266
4.885GlnVal: 4.885 ± 1.511
0.0GlnTrp: 0.0 ± 0.0
2.791GlnTyr: 2.791 ± 1.245
0.0GlnXaa: 0.0 ± 0.0
Arg
12.561ArgAla: 12.561 ± 1.596
1.396ArgCys: 1.396 ± 0.622
5.583ArgAsp: 5.583 ± 1.154
8.374ArgGlu: 8.374 ± 2.399
4.187ArgPhe: 4.187 ± 0.803
6.978ArgGly: 6.978 ± 0.893
2.094ArgHis: 2.094 ± 0.266
2.094ArgIle: 2.094 ± 0.266
3.489ArgLys: 3.489 ± 0.888
6.978ArgLeu: 6.978 ± 0.893
0.0ArgMet: 0.0 ± 0.0
8.374ArgAsn: 8.374 ± 2.399
4.885ArgPro: 4.885 ± 0.176
0.698ArgGln: 0.698 ± 0.356
9.77ArgArg: 9.77 ± 0.351
1.396ArgSer: 1.396 ± 0.713
4.885ArgThr: 4.885 ± 1.511
4.187ArgVal: 4.187 ± 0.803
0.698ArgTrp: 0.698 ± 0.356
2.791ArgTyr: 2.791 ± 1.425
0.0ArgXaa: 0.0 ± 0.0
Ser
2.791SerAla: 2.791 ± 1.245
0.698SerCys: 0.698 ± 0.356
0.698SerAsp: 0.698 ± 0.356
2.094SerGlu: 2.094 ± 0.266
2.791SerPhe: 2.791 ± 0.09
3.489SerGly: 3.489 ± 0.447
1.396SerHis: 1.396 ± 0.713
1.396SerIle: 1.396 ± 0.713
4.187SerLys: 4.187 ± 0.803
4.187SerLeu: 4.187 ± 2.138
0.698SerMet: 0.698 ± 0.356
2.094SerAsn: 2.094 ± 1.601
3.489SerPro: 3.489 ± 0.888
1.396SerGln: 1.396 ± 0.713
1.396SerArg: 1.396 ± 0.622
6.281SerSer: 6.281 ± 1.872
4.187SerThr: 4.187 ± 0.532
2.791SerVal: 2.791 ± 0.09
1.396SerTrp: 1.396 ± 0.713
1.396SerTyr: 1.396 ± 0.622
0.0SerXaa: 0.0 ± 0.0
Thr
2.791ThrAla: 2.791 ± 0.09
0.0ThrCys: 0.0 ± 0.0
2.094ThrAsp: 2.094 ± 0.266
2.791ThrGlu: 2.791 ± 1.245
4.187ThrPhe: 4.187 ± 1.867
1.396ThrGly: 1.396 ± 0.622
0.0ThrHis: 0.0 ± 0.0
3.489ThrIle: 3.489 ± 0.888
5.583ThrLys: 5.583 ± 0.181
2.791ThrLeu: 2.791 ± 1.425
1.396ThrMet: 1.396 ± 0.713
1.396ThrAsn: 1.396 ± 0.622
1.396ThrPro: 1.396 ± 0.622
2.791ThrGln: 2.791 ± 1.245
12.561ThrArg: 12.561 ± 2.931
4.885ThrSer: 4.885 ± 0.176
2.094ThrThr: 2.094 ± 0.266
2.094ThrVal: 2.094 ± 0.266
0.0ThrTrp: 0.0 ± 0.0
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
6.978ValAla: 6.978 ± 1.777
0.0ValCys: 0.0 ± 0.0
6.281ValAsp: 6.281 ± 0.798
4.885ValGlu: 4.885 ± 1.511
1.396ValPhe: 1.396 ± 0.622
2.791ValGly: 2.791 ± 1.425
1.396ValHis: 1.396 ± 0.713
2.094ValIle: 2.094 ± 0.266
3.489ValLys: 3.489 ± 0.888
2.094ValLeu: 2.094 ± 0.266
2.791ValMet: 2.791 ± 1.425
1.396ValAsn: 1.396 ± 0.713
3.489ValPro: 3.489 ± 0.447
3.489ValGln: 3.489 ± 0.888
9.072ValArg: 9.072 ± 0.708
2.094ValSer: 2.094 ± 1.069
4.187ValThr: 4.187 ± 0.803
4.187ValVal: 4.187 ± 1.867
0.698ValTrp: 0.698 ± 0.356
0.698ValTyr: 0.698 ± 0.356
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
1.396TrpCys: 1.396 ± 0.713
2.094TrpAsp: 2.094 ± 0.266
1.396TrpGlu: 1.396 ± 0.713
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.396TrpIle: 1.396 ± 0.713
1.396TrpLys: 1.396 ± 0.622
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.698TrpPro: 0.698 ± 0.356
0.0TrpGln: 0.0 ± 0.0
3.489TrpArg: 3.489 ± 1.782
1.396TrpSer: 1.396 ± 0.713
2.094TrpThr: 2.094 ± 0.266
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.698TyrAla: 0.698 ± 0.356
1.396TyrCys: 1.396 ± 0.622
2.094TyrAsp: 2.094 ± 1.069
1.396TyrGlu: 1.396 ± 0.622
0.0TyrPhe: 0.0 ± 0.0
0.698TyrGly: 0.698 ± 0.356
0.0TyrHis: 0.0 ± 0.0
2.094TyrIle: 2.094 ± 1.069
0.698TyrLys: 0.698 ± 0.356
2.094TyrLeu: 2.094 ± 0.266
0.0TyrMet: 0.0 ± 0.0
1.396TyrAsn: 1.396 ± 0.713
2.094TyrPro: 2.094 ± 1.069
1.396TyrGln: 1.396 ± 0.622
1.396TyrArg: 1.396 ± 0.713
0.698TyrSer: 0.698 ± 0.356
0.698TyrThr: 0.698 ± 0.356
2.094TyrVal: 2.094 ± 1.601
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1434 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski