Amino acid dipepetide frequency for Citrus psorosis virus (isolate Spain/P-121) (CPsV) (Citrus ringspot virus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.848AlaAla: 0.848 ± 0.527
0.283AlaCys: 0.283 ± 0.156
2.828AlaAsp: 2.828 ± 0.637
3.394AlaGlu: 3.394 ± 1.783
1.697AlaPhe: 1.697 ± 1.363
2.262AlaGly: 2.262 ± 1.369
0.566AlaHis: 0.566 ± 0.311
3.111AlaIle: 3.111 ± 0.985
3.111AlaLys: 3.111 ± 0.679
3.111AlaLeu: 3.111 ± 1.277
0.566AlaMet: 0.566 ± 0.334
0.848AlaAsn: 0.848 ± 0.323
0.848AlaPro: 0.848 ± 0.527
1.131AlaGln: 1.131 ± 0.382
1.697AlaArg: 1.697 ± 0.611
4.525AlaSer: 4.525 ± 0.904
0.848AlaThr: 0.848 ± 0.385
3.111AlaVal: 3.111 ± 0.772
1.131AlaTrp: 1.131 ± 0.638
1.697AlaTyr: 1.697 ± 0.611
0.0AlaXaa: 0.0 ± 0.0
Cys
0.283CysAla: 0.283 ± 0.512
0.283CysCys: 0.283 ± 0.156
1.131CysAsp: 1.131 ± 0.77
0.283CysGlu: 0.283 ± 0.156
0.566CysPhe: 0.566 ± 0.311
0.848CysGly: 0.848 ± 0.323
0.0CysHis: 0.0 ± 0.0
0.848CysIle: 0.848 ± 0.667
0.848CysLys: 0.848 ± 0.385
0.848CysLeu: 0.848 ± 0.467
1.414CysMet: 1.414 ± 0.639
0.566CysAsn: 0.566 ± 0.729
0.283CysPro: 0.283 ± 0.156
0.283CysGln: 0.283 ± 0.817
0.283CysArg: 0.283 ± 0.156
1.414CysSer: 1.414 ± 0.478
0.848CysThr: 0.848 ± 0.467
0.283CysVal: 0.283 ± 0.156
0.0CysTrp: 0.0 ± 0.0
0.283CysTyr: 0.283 ± 0.156
0.0CysXaa: 0.0 ± 0.0
Asp
1.98AspAla: 1.98 ± 0.929
0.848AspCys: 0.848 ± 0.667
4.525AspAsp: 4.525 ± 0.962
6.222AspGlu: 6.222 ± 0.606
1.98AspPhe: 1.98 ± 0.678
4.808AspGly: 4.808 ± 3.634
1.697AspHis: 1.697 ± 0.933
4.242AspIle: 4.242 ± 0.469
6.505AspLys: 6.505 ± 1.228
3.394AspLeu: 3.394 ± 1.003
2.828AspMet: 2.828 ± 0.347
3.394AspAsn: 3.394 ± 1.219
1.131AspPro: 1.131 ± 0.382
1.697AspGln: 1.697 ± 1.054
3.111AspArg: 3.111 ± 0.617
3.394AspSer: 3.394 ± 1.925
1.98AspThr: 1.98 ± 0.678
3.676AspVal: 3.676 ± 1.064
0.283AspTrp: 0.283 ± 0.156
1.98AspTyr: 1.98 ± 0.69
0.0AspXaa: 0.0 ± 0.0
Glu
3.111GluAla: 3.111 ± 0.617
0.848GluCys: 0.848 ± 0.467
4.525GluAsp: 4.525 ± 2.551
11.878GluGlu: 11.878 ± 2.876
1.697GluPhe: 1.697 ± 1.008
5.656GluGly: 5.656 ± 1.273
1.697GluHis: 1.697 ± 0.647
9.333GluIle: 9.333 ± 1.384
9.898GluLys: 9.898 ± 0.894
10.747GluLeu: 10.747 ± 2.85
3.111GluMet: 3.111 ± 0.849
6.222GluAsn: 6.222 ± 0.589
1.414GluPro: 1.414 ± 0.778
2.262GluGln: 2.262 ± 1.485
3.111GluArg: 3.111 ± 1.116
3.959GluSer: 3.959 ± 0.787
4.525GluThr: 4.525 ± 0.962
2.828GluVal: 2.828 ± 1.803
0.283GluTrp: 0.283 ± 0.156
2.828GluTyr: 2.828 ± 0.783
0.0GluXaa: 0.0 ± 0.0
Phe
0.848PheAla: 0.848 ± 0.385
0.0PheCys: 0.0 ± 0.0
2.262PheAsp: 2.262 ± 0.891
1.414PheGlu: 1.414 ± 0.485
2.545PhePhe: 2.545 ± 1.167
2.545PheGly: 2.545 ± 1.252
1.131PheHis: 1.131 ± 0.622
4.525PheIle: 4.525 ± 1.264
3.111PheLys: 3.111 ± 0.772
3.111PheLeu: 3.111 ± 1.05
1.98PheMet: 1.98 ± 1.384
1.98PheAsn: 1.98 ± 0.763
0.848PhePro: 0.848 ± 0.385
1.98PheGln: 1.98 ± 1.258
1.98PheArg: 1.98 ± 0.763
3.676PheSer: 3.676 ± 0.809
1.697PheThr: 1.697 ± 1.363
2.262PheVal: 2.262 ± 0.622
0.283PheTrp: 0.283 ± 0.817
1.98PheTyr: 1.98 ± 0.748
0.0PheXaa: 0.0 ± 0.0
Gly
1.131GlyAla: 1.131 ± 0.85
0.0GlyCys: 0.0 ± 0.0
3.394GlyAsp: 3.394 ± 1.606
4.242GlyGlu: 4.242 ± 1.693
1.98GlyPhe: 1.98 ± 0.775
2.262GlyGly: 2.262 ± 0.764
1.131GlyHis: 1.131 ± 0.382
3.394GlyIle: 3.394 ± 1.219
5.09GlyLys: 5.09 ± 0.897
4.525GlyLeu: 4.525 ± 1.338
1.131GlyMet: 1.131 ± 0.382
3.111GlyAsn: 3.111 ± 0.592
0.848GlyPro: 0.848 ± 0.385
1.98GlyGln: 1.98 ± 0.344
2.828GlyArg: 2.828 ± 0.712
2.545GlySer: 2.545 ± 0.824
2.262GlyThr: 2.262 ± 0.481
4.808GlyVal: 4.808 ± 0.877
0.283GlyTrp: 0.283 ± 0.156
1.98GlyTyr: 1.98 ± 1.089
0.0GlyXaa: 0.0 ± 0.0
His
0.848HisAla: 0.848 ± 0.385
0.283HisCys: 0.283 ± 0.156
0.848HisAsp: 0.848 ± 0.385
0.566HisGlu: 0.566 ± 0.729
0.848HisPhe: 0.848 ± 0.385
0.283HisGly: 0.283 ± 0.409
0.283HisHis: 0.283 ± 0.156
1.414HisIle: 1.414 ± 0.485
1.98HisLys: 1.98 ± 0.622
1.697HisLeu: 1.697 ± 0.933
0.283HisMet: 0.283 ± 0.156
1.131HisAsn: 1.131 ± 0.638
0.283HisPro: 0.283 ± 0.512
0.0HisGln: 0.0 ± 0.0
1.131HisArg: 1.131 ± 0.622
0.0HisSer: 0.0 ± 0.0
0.848HisThr: 0.848 ± 0.467
0.566HisVal: 0.566 ± 0.334
0.0HisTrp: 0.0 ± 0.0
0.848HisTyr: 0.848 ± 0.323
0.0HisXaa: 0.0 ± 0.0
Ile
3.111IleAla: 3.111 ± 1.056
0.566IleCys: 0.566 ± 0.311
6.505IleAsp: 6.505 ± 1.468
9.898IleGlu: 9.898 ± 1.909
2.828IlePhe: 2.828 ± 0.956
3.959IleGly: 3.959 ± 1.021
0.283IleHis: 0.283 ± 0.409
9.615IleIle: 9.615 ± 2.011
10.747IleLys: 10.747 ± 2.486
8.201IleLeu: 8.201 ± 0.614
2.828IleMet: 2.828 ± 1.092
6.222IleAsn: 6.222 ± 1.665
1.697IlePro: 1.697 ± 0.728
3.394IleGln: 3.394 ± 1.219
3.394IleArg: 3.394 ± 1.168
7.353IleSer: 7.353 ± 1.264
7.353IleThr: 7.353 ± 1.383
3.394IleVal: 3.394 ± 1.222
0.566IleTrp: 0.566 ± 0.729
1.697IleTyr: 1.697 ± 0.596
0.0IleXaa: 0.0 ± 0.0
Lys
3.959LysAla: 3.959 ± 1.156
1.131LysCys: 1.131 ± 0.622
5.939LysAsp: 5.939 ± 2.541
8.201LysGlu: 8.201 ± 1.53
3.394LysPhe: 3.394 ± 0.726
3.394LysGly: 3.394 ± 0.97
0.848LysHis: 0.848 ± 0.385
9.333LysIle: 9.333 ± 3.058
8.201LysLys: 8.201 ± 2.13
10.464LysLeu: 10.464 ± 1.511
3.676LysMet: 3.676 ± 0.389
6.787LysAsn: 6.787 ± 0.611
2.262LysPro: 2.262 ± 1.176
1.697LysGln: 1.697 ± 0.77
5.656LysArg: 5.656 ± 0.97
7.636LysSer: 7.636 ± 2.612
6.505LysThr: 6.505 ± 4.194
4.808LysVal: 4.808 ± 0.835
1.697LysTrp: 1.697 ± 0.596
3.111LysTyr: 3.111 ± 1.711
0.0LysXaa: 0.0 ± 0.0
Leu
3.676LeuAla: 3.676 ± 0.62
0.0LeuCys: 0.0 ± 0.0
5.373LeuAsp: 5.373 ± 1.284
9.615LeuGlu: 9.615 ± 1.935
4.808LeuPhe: 4.808 ± 1.062
2.262LeuGly: 2.262 ± 0.956
0.848LeuHis: 0.848 ± 0.886
7.353LeuIle: 7.353 ± 1.943
11.312LeuLys: 11.312 ± 1.65
7.353LeuLeu: 7.353 ± 0.95
3.394LeuMet: 3.394 ± 1.051
6.787LeuAsn: 6.787 ± 1.325
1.98LeuPro: 1.98 ± 0.775
0.566LeuGln: 0.566 ± 0.311
5.373LeuArg: 5.373 ± 1.705
9.05LeuSer: 9.05 ± 1.789
3.959LeuThr: 3.959 ± 1.971
4.242LeuVal: 4.242 ± 1.88
1.131LeuTrp: 1.131 ± 0.622
1.697LeuTyr: 1.697 ± 0.584
0.0LeuXaa: 0.0 ± 0.0
Met
3.394MetAla: 3.394 ± 1.219
0.283MetCys: 0.283 ± 0.156
0.848MetAsp: 0.848 ± 0.731
3.111MetGlu: 3.111 ± 1.084
0.848MetPhe: 0.848 ± 0.873
1.131MetGly: 1.131 ± 0.622
0.283MetHis: 0.283 ± 0.156
3.394MetIle: 3.394 ± 0.844
4.808MetLys: 4.808 ± 1.69
3.959MetLeu: 3.959 ± 1.776
2.545MetMet: 2.545 ± 0.554
2.262MetAsn: 2.262 ± 0.764
1.131MetPro: 1.131 ± 0.77
1.131MetGln: 1.131 ± 0.382
1.697MetArg: 1.697 ± 0.611
1.98MetSer: 1.98 ± 0.596
3.111MetThr: 3.111 ± 1.222
1.98MetVal: 1.98 ± 0.748
0.283MetTrp: 0.283 ± 0.409
0.848MetTyr: 0.848 ± 0.323
0.0MetXaa: 0.0 ± 0.0
Asn
0.848AsnAla: 0.848 ± 0.467
1.414AsnCys: 1.414 ± 0.646
3.676AsnAsp: 3.676 ± 0.377
6.787AsnGlu: 6.787 ± 1.886
3.394AsnPhe: 3.394 ± 0.97
1.697AsnGly: 1.697 ± 0.611
1.131AsnHis: 1.131 ± 0.622
7.07AsnIle: 7.07 ± 1.328
4.525AsnLys: 4.525 ± 1.013
4.242AsnLeu: 4.242 ± 0.469
3.111AsnMet: 3.111 ± 1.913
3.394AsnAsn: 3.394 ± 1.357
1.414AsnPro: 1.414 ± 1.125
1.98AsnGln: 1.98 ± 0.678
3.111AsnArg: 3.111 ± 0.857
4.808AsnSer: 4.808 ± 2.508
3.111AsnThr: 3.111 ± 1.092
1.697AsnVal: 1.697 ± 1.003
0.283AsnTrp: 0.283 ± 0.817
1.414AsnTyr: 1.414 ± 0.778
0.0AsnXaa: 0.0 ± 0.0
Pro
1.414ProAla: 1.414 ± 1.947
0.283ProCys: 0.283 ± 0.409
0.566ProAsp: 0.566 ± 1.023
1.98ProGlu: 1.98 ± 1.451
0.566ProPhe: 0.566 ± 0.334
1.697ProGly: 1.697 ± 0.584
0.566ProHis: 0.566 ± 1.013
1.98ProIle: 1.98 ± 0.527
1.414ProLys: 1.414 ± 0.646
1.98ProLeu: 1.98 ± 1.052
1.131ProMet: 1.131 ± 0.382
1.414ProAsn: 1.414 ± 0.485
0.848ProPro: 0.848 ± 1.228
1.131ProGln: 1.131 ± 0.382
0.283ProArg: 0.283 ± 0.156
2.545ProSer: 2.545 ± 0.985
2.262ProThr: 2.262 ± 1.165
0.566ProVal: 0.566 ± 0.334
0.0ProTrp: 0.0 ± 0.0
0.283ProTyr: 0.283 ± 0.156
0.0ProXaa: 0.0 ± 0.0
Gln
0.848GlnAla: 0.848 ± 0.385
0.283GlnCys: 0.283 ± 0.409
2.262GlnAsp: 2.262 ± 0.795
2.828GlnGlu: 2.828 ± 1.198
1.131GlnPhe: 1.131 ± 0.382
2.262GlnGly: 2.262 ± 0.81
0.566GlnHis: 0.566 ± 0.729
1.697GlnIle: 1.697 ± 1.276
2.828GlnLys: 2.828 ± 1.827
3.394GlnLeu: 3.394 ± 0.586
1.131GlnMet: 1.131 ± 0.772
1.414GlnAsn: 1.414 ± 0.671
0.848GlnPro: 0.848 ± 0.323
0.0GlnGln: 0.0 ± 0.0
1.131GlnArg: 1.131 ± 0.382
1.98GlnSer: 1.98 ± 0.968
1.414GlnThr: 1.414 ± 0.478
0.566GlnVal: 0.566 ± 0.425
0.566GlnTrp: 0.566 ± 0.662
0.566GlnTyr: 0.566 ± 0.311
0.0GlnXaa: 0.0 ± 0.0
Arg
2.262ArgAla: 2.262 ± 0.898
1.414ArgCys: 1.414 ± 0.671
1.697ArgAsp: 1.697 ± 1.054
3.676ArgGlu: 3.676 ± 0.923
1.131ArgPhe: 1.131 ± 0.622
1.414ArgGly: 1.414 ± 0.778
0.283ArgHis: 0.283 ± 0.156
5.656ArgIle: 5.656 ± 1.682
4.525ArgLys: 4.525 ± 1.264
4.808ArgLeu: 4.808 ± 1.39
2.545ArgMet: 2.545 ± 1.038
2.262ArgAsn: 2.262 ± 0.844
0.848ArgPro: 0.848 ± 0.323
0.566ArgGln: 0.566 ± 0.311
1.697ArgArg: 1.697 ± 1.462
1.414ArgSer: 1.414 ± 0.868
2.545ArgThr: 2.545 ± 0.482
3.676ArgVal: 3.676 ± 1.034
0.566ArgTrp: 0.566 ± 0.311
1.697ArgTyr: 1.697 ± 0.584
0.0ArgXaa: 0.0 ± 0.0
Ser
2.828SerAla: 2.828 ± 1.209
0.848SerCys: 0.848 ± 0.667
6.505SerAsp: 6.505 ± 1.101
5.09SerGlu: 5.09 ± 0.865
2.828SerPhe: 2.828 ± 0.571
3.676SerGly: 3.676 ± 1.154
1.98SerHis: 1.98 ± 0.344
7.353SerIle: 7.353 ± 0.7
5.373SerLys: 5.373 ± 0.932
5.939SerLeu: 5.939 ± 1.735
2.828SerMet: 2.828 ± 0.531
3.676SerAsn: 3.676 ± 1.142
2.262SerPro: 2.262 ± 0.909
2.828SerGln: 2.828 ± 0.637
3.394SerArg: 3.394 ± 2.125
8.484SerSer: 8.484 ± 3.099
3.111SerThr: 3.111 ± 0.706
4.525SerVal: 4.525 ± 1.368
0.283SerTrp: 0.283 ± 0.156
5.09SerTyr: 5.09 ± 1.557
0.0SerXaa: 0.0 ± 0.0
Thr
2.545ThrAla: 2.545 ± 1.559
1.131ThrCys: 1.131 ± 0.405
1.414ThrAsp: 1.414 ± 0.866
4.242ThrGlu: 4.242 ± 1.227
2.262ThrPhe: 2.262 ± 0.898
3.394ThrGly: 3.394 ± 1.004
0.283ThrHis: 0.283 ± 0.156
3.959ThrIle: 3.959 ± 1.773
5.939ThrLys: 5.939 ± 1.953
5.939ThrLeu: 5.939 ± 1.144
1.98ThrMet: 1.98 ± 0.929
2.828ThrAsn: 2.828 ± 0.623
0.848ThrPro: 0.848 ± 1.111
2.828ThrGln: 2.828 ± 1.158
1.131ThrArg: 1.131 ± 1.414
4.525ThrSer: 4.525 ± 1.54
1.131ThrThr: 1.131 ± 0.622
1.98ThrVal: 1.98 ± 0.678
0.283ThrTrp: 0.283 ± 0.512
2.828ThrTyr: 2.828 ± 0.677
0.0ThrXaa: 0.0 ± 0.0
Val
1.697ValAla: 1.697 ± 0.762
1.131ValCys: 1.131 ± 0.85
3.394ValAsp: 3.394 ± 0.435
4.808ValGlu: 4.808 ± 1.799
2.545ValPhe: 2.545 ± 0.696
1.697ValGly: 1.697 ± 0.584
0.283ValHis: 0.283 ± 0.156
3.959ValIle: 3.959 ± 0.985
4.242ValLys: 4.242 ± 0.966
3.676ValLeu: 3.676 ± 0.91
1.131ValMet: 1.131 ± 0.772
1.98ValAsn: 1.98 ± 0.748
1.98ValPro: 1.98 ± 0.527
1.98ValGln: 1.98 ± 0.857
2.545ValArg: 2.545 ± 0.6
5.09ValSer: 5.09 ± 1.399
1.98ValThr: 1.98 ± 0.972
2.262ValVal: 2.262 ± 0.891
0.566ValTrp: 0.566 ± 0.334
1.697ValTyr: 1.697 ± 0.584
0.283ValXaa: 0.283 ± 0.156
Trp
0.566TrpAla: 0.566 ± 0.334
0.0TrpCys: 0.0 ± 0.0
0.283TrpAsp: 0.283 ± 0.156
0.283TrpGlu: 0.283 ± 0.512
0.848TrpPhe: 0.848 ± 0.467
0.848TrpGly: 0.848 ± 0.667
0.0TrpHis: 0.0 ± 0.0
1.131TrpIle: 1.131 ± 1.658
0.848TrpLys: 0.848 ± 0.385
0.283TrpLeu: 0.283 ± 0.156
0.848TrpMet: 0.848 ± 0.667
0.848TrpAsn: 0.848 ± 0.667
0.283TrpPro: 0.283 ± 0.409
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
1.131TrpSer: 1.131 ± 0.405
0.283TrpThr: 0.283 ± 0.156
0.283TrpVal: 0.283 ± 0.156
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.414TyrAla: 1.414 ± 0.478
0.283TyrCys: 0.283 ± 0.409
1.697TyrAsp: 1.697 ± 0.584
1.697TyrGlu: 1.697 ± 0.933
2.262TyrPhe: 2.262 ± 0.891
2.828TyrGly: 2.828 ± 0.347
0.283TyrHis: 0.283 ± 0.156
4.242TyrIle: 4.242 ± 1.399
3.394TyrLys: 3.394 ± 0.844
3.111TyrLeu: 3.111 ± 1.338
0.283TyrMet: 0.283 ± 0.156
1.98TyrAsn: 1.98 ± 1.089
0.848TyrPro: 0.848 ± 0.467
0.283TyrGln: 0.283 ± 0.156
1.131TyrArg: 1.131 ± 0.382
3.394TyrSer: 3.394 ± 1.426
1.697TyrThr: 1.697 ± 0.293
1.414TyrVal: 1.414 ± 0.478
0.283TyrTrp: 0.283 ± 0.156
0.566TyrTyr: 0.566 ± 0.311
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.283XaaCys: 0.283 ± 0.156
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3537 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski