Amino acid dipepetide frequency for Papaya leaf curl virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.149AlaAla: 7.149 ± 3.6
1.787AlaCys: 1.787 ± 1.232
0.894AlaAsp: 0.894 ± 0.75
3.575AlaGlu: 3.575 ± 1.981
0.894AlaPhe: 0.894 ± 0.966
1.787AlaGly: 1.787 ± 0.78
3.575AlaHis: 3.575 ± 2.582
2.681AlaIle: 2.681 ± 1.316
3.575AlaLys: 3.575 ± 1.155
8.937AlaLeu: 8.937 ± 1.956
0.0AlaMet: 0.0 ± 0.0
2.681AlaAsn: 2.681 ± 1.252
1.787AlaPro: 1.787 ± 1.232
4.468AlaGln: 4.468 ± 1.902
4.468AlaArg: 4.468 ± 2.374
4.468AlaSer: 4.468 ± 2.09
3.575AlaThr: 3.575 ± 2.194
1.787AlaVal: 1.787 ± 1.2
1.787AlaTrp: 1.787 ± 0.78
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.787CysCys: 1.787 ± 1.776
0.0CysAsp: 0.0 ± 0.0
0.894CysGlu: 0.894 ± 0.75
1.787CysPhe: 1.787 ± 1.2
1.787CysGly: 1.787 ± 0.979
0.894CysHis: 0.894 ± 1.048
0.894CysIle: 0.894 ± 1.426
0.894CysLys: 0.894 ± 0.75
0.0CysLeu: 0.0 ± 0.0
0.894CysMet: 0.894 ± 0.888
1.787CysAsn: 1.787 ± 1.351
3.575CysPro: 3.575 ± 1.974
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
2.681CysSer: 2.681 ± 2.265
0.894CysThr: 0.894 ± 0.75
3.575CysVal: 3.575 ± 1.309
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.787AspAla: 1.787 ± 1.351
0.0AspCys: 0.0 ± 0.0
1.787AspAsp: 1.787 ± 0.979
1.787AspGlu: 1.787 ± 0.78
1.787AspPhe: 1.787 ± 0.78
1.787AspGly: 1.787 ± 1.351
0.894AspHis: 0.894 ± 0.966
3.575AspIle: 3.575 ± 2.028
1.787AspLys: 1.787 ± 0.78
5.362AspLeu: 5.362 ± 2.637
0.0AspMet: 0.0 ± 0.0
1.787AspAsn: 1.787 ± 1.232
1.787AspPro: 1.787 ± 0.987
2.681AspGln: 2.681 ± 1.419
1.787AspArg: 1.787 ± 1.5
5.362AspSer: 5.362 ± 1.241
2.681AspThr: 2.681 ± 2.265
6.256AspVal: 6.256 ± 2.012
2.681AspTrp: 2.681 ± 1.316
0.894AspTyr: 0.894 ± 0.675
0.0AspXaa: 0.0 ± 0.0
Glu
4.468GluAla: 4.468 ± 1.752
0.0GluCys: 0.0 ± 0.0
0.894GluAsp: 0.894 ± 1.426
4.468GluGlu: 4.468 ± 1.824
2.681GluPhe: 2.681 ± 1.44
4.468GluGly: 4.468 ± 1.752
1.787GluHis: 1.787 ± 1.932
1.787GluIle: 1.787 ± 1.009
3.575GluLys: 3.575 ± 2.701
2.681GluLeu: 2.681 ± 1.621
0.0GluMet: 0.0 ± 0.0
5.362GluAsn: 5.362 ± 1.799
2.681GluPro: 2.681 ± 1.739
3.575GluGln: 3.575 ± 1.058
0.894GluArg: 0.894 ± 0.675
2.681GluSer: 2.681 ± 0.985
1.787GluThr: 1.787 ± 1.647
2.681GluVal: 2.681 ± 1.269
1.787GluTrp: 1.787 ± 0.979
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
1.787PheCys: 1.787 ± 0.78
3.575PheAsp: 3.575 ± 1.561
1.787PheGlu: 1.787 ± 1.003
0.894PhePhe: 0.894 ± 0.75
0.894PheGly: 0.894 ± 0.75
1.787PheHis: 1.787 ± 0.987
4.468PheIle: 4.468 ± 1.04
3.575PheLys: 3.575 ± 2.017
7.149PheLeu: 7.149 ± 2.518
0.894PheMet: 0.894 ± 0.675
2.681PheAsn: 2.681 ± 1.937
2.681PhePro: 2.681 ± 2.05
3.575PheGln: 3.575 ± 1.848
3.575PheArg: 3.575 ± 1.659
0.894PheSer: 0.894 ± 0.675
1.787PheThr: 1.787 ± 1.364
0.894PheVal: 0.894 ± 0.675
0.0PheTrp: 0.0 ± 0.0
0.894PheTyr: 0.894 ± 0.75
0.0PheXaa: 0.0 ± 0.0
Gly
2.681GlyAla: 2.681 ± 1.604
1.787GlyCys: 1.787 ± 1.232
4.468GlyAsp: 4.468 ± 2.219
2.681GlyGlu: 2.681 ± 1.177
1.787GlyPhe: 1.787 ± 1.364
2.681GlyGly: 2.681 ± 1.252
0.894GlyHis: 0.894 ± 0.675
2.681GlyIle: 2.681 ± 1.856
6.256GlyLys: 6.256 ± 2.861
2.681GlyLeu: 2.681 ± 1.723
0.0GlyMet: 0.0 ± 0.0
0.0GlyAsn: 0.0 ± 0.0
4.468GlyPro: 4.468 ± 1.752
1.787GlyGln: 1.787 ± 0.78
1.787GlyArg: 1.787 ± 1.009
2.681GlySer: 2.681 ± 2.026
4.468GlyThr: 4.468 ± 1.911
0.894GlyVal: 0.894 ± 0.966
0.0GlyTrp: 0.0 ± 0.0
0.894GlyTyr: 0.894 ± 0.888
0.0GlyXaa: 0.0 ± 0.0
His
3.575HisAla: 3.575 ± 1.058
1.787HisCys: 1.787 ± 1.364
0.894HisAsp: 0.894 ± 0.75
0.894HisGlu: 0.894 ± 0.888
3.575HisPhe: 3.575 ± 1.646
1.787HisGly: 1.787 ± 1.364
3.575HisHis: 3.575 ± 3.209
1.787HisIle: 1.787 ± 0.78
0.894HisLys: 0.894 ± 0.966
0.894HisLeu: 0.894 ± 0.675
0.0HisMet: 0.0 ± 0.0
3.575HisAsn: 3.575 ± 1.407
1.787HisPro: 1.787 ± 1.351
1.787HisGln: 1.787 ± 0.987
4.468HisArg: 4.468 ± 3.359
2.681HisSer: 2.681 ± 1.418
0.894HisThr: 0.894 ± 0.75
1.787HisVal: 1.787 ± 1.932
0.0HisTrp: 0.0 ± 0.0
0.894HisTyr: 0.894 ± 0.675
0.0HisXaa: 0.0 ± 0.0
Ile
0.894IleAla: 0.894 ± 1.048
0.0IleCys: 0.0 ± 0.0
2.681IleAsp: 2.681 ± 2.026
1.787IleGlu: 1.787 ± 1.351
3.575IlePhe: 3.575 ± 2.701
1.787IleGly: 1.787 ± 1.107
1.787IleHis: 1.787 ± 1.009
3.575IleIle: 3.575 ± 1.381
3.575IleLys: 3.575 ± 1.044
0.894IleLeu: 0.894 ± 0.675
0.0IleMet: 0.0 ± 0.0
3.575IleAsn: 3.575 ± 1.407
2.681IlePro: 2.681 ± 1.316
3.575IleGln: 3.575 ± 1.748
8.043IleArg: 8.043 ± 2.941
4.468IleSer: 4.468 ± 2.575
4.468IleThr: 4.468 ± 4.225
4.468IleVal: 4.468 ± 1.503
2.681IleTrp: 2.681 ± 1.937
2.681IleTyr: 2.681 ± 0.949
0.0IleXaa: 0.0 ± 0.0
Lys
4.468LysAla: 4.468 ± 1.754
2.681LysCys: 2.681 ± 1.419
1.787LysAsp: 1.787 ± 1.351
3.575LysGlu: 3.575 ± 1.854
2.681LysPhe: 2.681 ± 0.949
3.575LysGly: 3.575 ± 1.958
1.787LysHis: 1.787 ± 1.351
2.681LysIle: 2.681 ± 1.625
1.787LysLys: 1.787 ± 1.232
2.681LysLeu: 2.681 ± 1.44
0.0LysMet: 0.0 ± 0.0
5.362LysAsn: 5.362 ± 2.504
2.681LysPro: 2.681 ± 1.373
0.0LysGln: 0.0 ± 0.0
1.787LysArg: 1.787 ± 1.5
6.256LysSer: 6.256 ± 1.845
2.681LysThr: 2.681 ± 0.949
5.362LysVal: 5.362 ± 2.096
0.894LysTrp: 0.894 ± 0.75
3.575LysTyr: 3.575 ± 0.889
0.0LysXaa: 0.0 ± 0.0
Leu
4.468LeuAla: 4.468 ± 2.016
3.575LeuCys: 3.575 ± 1.646
2.681LeuAsp: 2.681 ± 1.316
4.468LeuGlu: 4.468 ± 2.597
0.894LeuPhe: 0.894 ± 0.675
5.362LeuGly: 5.362 ± 1.631
0.894LeuHis: 0.894 ± 0.675
5.362LeuIle: 5.362 ± 2.782
6.256LeuLys: 6.256 ± 1.95
0.894LeuLeu: 0.894 ± 0.888
4.468LeuMet: 4.468 ± 3.027
3.575LeuAsn: 3.575 ± 0.889
2.681LeuPro: 2.681 ± 1.912
3.575LeuGln: 3.575 ± 2.757
3.575LeuArg: 3.575 ± 1.906
1.787LeuSer: 1.787 ± 1.359
3.575LeuThr: 3.575 ± 1.333
3.575LeuVal: 3.575 ± 2.005
0.894LeuTrp: 0.894 ± 0.966
2.681LeuTyr: 2.681 ± 0.949
0.0LeuXaa: 0.0 ± 0.0
Met
0.894MetAla: 0.894 ± 0.75
0.894MetCys: 0.894 ± 0.75
1.787MetAsp: 1.787 ± 1.107
1.787MetGlu: 1.787 ± 1.359
2.681MetPhe: 2.681 ± 1.751
2.681MetGly: 2.681 ± 1.502
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
3.575MetLeu: 3.575 ± 1.293
0.894MetMet: 0.894 ± 1.426
1.787MetAsn: 1.787 ± 1.107
1.787MetPro: 1.787 ± 1.359
0.0MetGln: 0.0 ± 0.0
0.894MetArg: 0.894 ± 1.048
2.681MetSer: 2.681 ± 2.814
1.787MetThr: 1.787 ± 1.2
0.0MetVal: 0.0 ± 0.0
1.787MetTrp: 1.787 ± 0.987
1.787MetTyr: 1.787 ± 1.5
0.0MetXaa: 0.0 ± 0.0
Asn
3.575AsnAla: 3.575 ± 1.854
0.894AsnCys: 0.894 ± 0.675
0.894AsnAsp: 0.894 ± 0.675
3.575AsnGlu: 3.575 ± 1.058
1.787AsnPhe: 1.787 ± 0.78
0.894AsnGly: 0.894 ± 0.966
3.575AsnHis: 3.575 ± 1.567
2.681AsnIle: 2.681 ± 0.949
0.0AsnLys: 0.0 ± 0.0
5.362AsnLeu: 5.362 ± 1.792
1.787AsnMet: 1.787 ± 1.449
3.575AsnAsn: 3.575 ± 1.748
4.468AsnPro: 4.468 ± 1.437
1.787AsnGln: 1.787 ± 0.78
6.256AsnArg: 6.256 ± 2.128
5.362AsnSer: 5.362 ± 2.301
1.787AsnThr: 1.787 ± 0.987
4.468AsnVal: 4.468 ± 1.809
0.894AsnTrp: 0.894 ± 0.675
2.681AsnTyr: 2.681 ± 0.884
0.0AsnXaa: 0.0 ± 0.0
Pro
3.575ProAla: 3.575 ± 1.868
2.681ProCys: 2.681 ± 1.392
3.575ProAsp: 3.575 ± 1.81
2.681ProGlu: 2.681 ± 1.205
2.681ProPhe: 2.681 ± 1.12
0.894ProGly: 0.894 ± 0.675
3.575ProHis: 3.575 ± 1.974
7.149ProIle: 7.149 ± 2.146
3.575ProLys: 3.575 ± 2.701
2.681ProLeu: 2.681 ± 1.12
2.681ProMet: 2.681 ± 1.199
5.362ProAsn: 5.362 ± 2.154
4.468ProPro: 4.468 ± 2.111
1.787ProGln: 1.787 ± 1.232
4.468ProArg: 4.468 ± 1.412
6.256ProSer: 6.256 ± 2.953
1.787ProThr: 1.787 ± 1.359
3.575ProVal: 3.575 ± 1.452
0.0ProTrp: 0.0 ± 0.0
0.894ProTyr: 0.894 ± 0.75
0.0ProXaa: 0.0 ± 0.0
Gln
3.575GlnAla: 3.575 ± 1.044
0.0GlnCys: 0.0 ± 0.0
4.468GlnAsp: 4.468 ± 1.687
3.575GlnGlu: 3.575 ± 1.388
2.681GlnPhe: 2.681 ± 1.419
0.894GlnGly: 0.894 ± 0.675
1.787GlnHis: 1.787 ± 1.232
2.681GlnIle: 2.681 ± 1.419
1.787GlnLys: 1.787 ± 1.776
2.681GlnLeu: 2.681 ± 2.229
1.787GlnMet: 1.787 ± 0.979
0.894GlnAsn: 0.894 ± 0.966
2.681GlnPro: 2.681 ± 1.53
3.575GlnGln: 3.575 ± 1.333
2.681GlnArg: 2.681 ± 1.468
6.256GlnSer: 6.256 ± 1.146
2.681GlnThr: 2.681 ± 1.604
3.575GlnVal: 3.575 ± 1.044
0.0GlnTrp: 0.0 ± 0.0
1.787GlnTyr: 1.787 ± 0.78
0.0GlnXaa: 0.0 ± 0.0
Arg
3.575ArgAla: 3.575 ± 1.25
1.787ArgCys: 1.787 ± 1.776
4.468ArgAsp: 4.468 ± 1.205
3.575ArgGlu: 3.575 ± 1.593
2.681ArgPhe: 2.681 ± 1.177
3.575ArgGly: 3.575 ± 1.452
3.575ArgHis: 3.575 ± 1.058
4.468ArgIle: 4.468 ± 1.053
3.575ArgLys: 3.575 ± 1.567
1.787ArgLeu: 1.787 ± 1.232
1.787ArgMet: 1.787 ± 1.5
1.787ArgAsn: 1.787 ± 0.987
6.256ArgPro: 6.256 ± 2.047
1.787ArgGln: 1.787 ± 1.647
6.256ArgArg: 6.256 ± 3.735
4.468ArgSer: 4.468 ± 1.224
2.681ArgThr: 2.681 ± 1.621
7.149ArgVal: 7.149 ± 3.004
0.0ArgTrp: 0.0 ± 0.0
1.787ArgTyr: 1.787 ± 1.003
0.0ArgXaa: 0.0 ± 0.0
Ser
3.575SerAla: 3.575 ± 2.701
0.0SerCys: 0.0 ± 0.0
4.468SerAsp: 4.468 ± 1.615
2.681SerGlu: 2.681 ± 1.269
3.575SerPhe: 3.575 ± 1.155
0.894SerGly: 0.894 ± 0.675
0.0SerHis: 0.0 ± 0.0
3.575SerIle: 3.575 ± 2.017
7.149SerLys: 7.149 ± 2.407
4.468SerLeu: 4.468 ± 1.589
4.468SerMet: 4.468 ± 4.253
3.575SerAsn: 3.575 ± 1.854
8.043SerPro: 8.043 ± 2.529
3.575SerGln: 3.575 ± 1.25
8.043SerArg: 8.043 ± 2.733
15.192SerSer: 15.192 ± 6.89
5.362SerThr: 5.362 ± 2.647
4.468SerVal: 4.468 ± 2.337
0.0SerTrp: 0.0 ± 0.0
2.681SerTyr: 2.681 ± 1.316
0.0SerXaa: 0.0 ± 0.0
Thr
3.575ThrAla: 3.575 ± 1.044
0.0ThrCys: 0.0 ± 0.0
0.0ThrAsp: 0.0 ± 0.0
0.894ThrGlu: 0.894 ± 0.966
0.894ThrPhe: 0.894 ± 0.675
4.468ThrGly: 4.468 ± 1.654
4.468ThrHis: 4.468 ± 2.127
0.894ThrIle: 0.894 ± 0.675
2.681ThrLys: 2.681 ± 1.373
3.575ThrLeu: 3.575 ± 1.293
1.787ThrMet: 1.787 ± 0.987
1.787ThrAsn: 1.787 ± 1.5
4.468ThrPro: 4.468 ± 2.575
4.468ThrGln: 4.468 ± 2.258
1.787ThrArg: 1.787 ± 1.232
5.362ThrSer: 5.362 ± 4.237
0.0ThrThr: 0.0 ± 0.0
5.362ThrVal: 5.362 ± 2.06
0.0ThrTrp: 0.0 ± 0.0
2.681ThrTyr: 2.681 ± 1.752
0.0ThrXaa: 0.0 ± 0.0
Val
1.787ValAla: 1.787 ± 0.78
0.894ValCys: 0.894 ± 0.888
4.468ValAsp: 4.468 ± 1.754
1.787ValGlu: 1.787 ± 1.776
3.575ValPhe: 3.575 ± 2.09
2.681ValGly: 2.681 ± 0.985
1.787ValHis: 1.787 ± 1.003
4.468ValIle: 4.468 ± 1.684
4.468ValLys: 4.468 ± 1.942
4.468ValLeu: 4.468 ± 3.004
1.787ValMet: 1.787 ± 1.5
3.575ValAsn: 3.575 ± 2.584
4.468ValPro: 4.468 ± 1.687
6.256ValGln: 6.256 ± 2.177
3.575ValArg: 3.575 ± 2.194
3.575ValSer: 3.575 ± 1.381
5.362ValThr: 5.362 ± 2.747
3.575ValVal: 3.575 ± 0.889
0.0ValTrp: 0.0 ± 0.0
6.256ValTyr: 6.256 ± 1.767
0.0ValXaa: 0.0 ± 0.0
Trp
3.575TrpAla: 3.575 ± 1.854
0.0TrpCys: 0.0 ± 0.0
0.894TrpAsp: 0.894 ± 0.888
0.894TrpGlu: 0.894 ± 0.966
0.0TrpPhe: 0.0 ± 0.0
0.894TrpGly: 0.894 ± 0.675
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
1.787TrpMet: 1.787 ± 1.107
0.894TrpAsn: 0.894 ± 0.966
0.0TrpPro: 0.0 ± 0.0
0.894TrpGln: 0.894 ± 0.675
0.894TrpArg: 0.894 ± 1.048
0.894TrpSer: 0.894 ± 1.048
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.787TrpTyr: 1.787 ± 0.78
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.681TyrAla: 2.681 ± 2.25
0.0TyrCys: 0.0 ± 0.0
1.787TyrAsp: 1.787 ± 1.003
0.894TyrGlu: 0.894 ± 0.75
2.681TyrPhe: 2.681 ± 1.418
1.787TyrGly: 1.787 ± 0.987
0.894TyrHis: 0.894 ± 0.675
1.787TyrIle: 1.787 ± 1.351
0.894TyrLys: 0.894 ± 0.675
4.468TyrLeu: 4.468 ± 1.301
1.787TyrMet: 1.787 ± 1.061
2.681TyrAsn: 2.681 ± 0.884
0.894TyrPro: 0.894 ± 0.675
0.894TyrGln: 0.894 ± 0.75
1.787TyrArg: 1.787 ± 1.5
2.681TyrSer: 2.681 ± 1.44
0.894TyrThr: 0.894 ± 0.675
5.362TyrVal: 5.362 ± 1.799
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1120 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski