Amino acid dipepetide frequency for Kutzneria buriramensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	20.433AlaAla: 20.433 ± 0.137	1.078AlaCys: 1.078 ± 0.017	8.661AlaAsp: 8.661 ± 0.055	8.003AlaGlu: 8.003 ± 0.059	3.503AlaPhe: 3.503 ± 0.032	12.552AlaGly: 12.552 ± 0.072	2.578AlaHis: 2.578 ± 0.031	4.373AlaIle: 4.373 ± 0.035	2.866AlaLys: 2.866 ± 0.033	13.733AlaLeu: 13.733 ± 0.084	2.626AlaMet: 2.626 ± 0.028	2.69AlaAsn: 2.69 ± 0.04	5.799AlaPro: 5.799 ± 0.052	3.988AlaGln: 3.988 ± 0.042	8.868AlaArg: 8.868 ± 0.064	6.052AlaSer: 6.052 ± 0.044	7.712AlaThr: 7.712 ± 0.054	12.32AlaVal: 12.32 ± 0.069	1.892AlaTrp: 1.892 ± 0.023	2.433AlaTyr: 2.433 ± 0.027	0.0AlaXaa: 0.0 ± 0.0
Cys	1.072CysAla: 1.072 ± 0.02	0.109CysCys: 0.109 ± 0.006	0.525CysAsp: 0.525 ± 0.012	0.403CysGlu: 0.403 ± 0.012	0.229CysPhe: 0.229 ± 0.008	0.975CysGly: 0.975 ± 0.019	0.208CysHis: 0.208 ± 0.009	0.174CysIle: 0.174 ± 0.007	0.122CysLys: 0.122 ± 0.006	0.81CysLeu: 0.81 ± 0.016	0.135CysMet: 0.135 ± 0.006	0.177CysAsn: 0.177 ± 0.009	0.507CysPro: 0.507 ± 0.012	0.24CysGln: 0.24 ± 0.008	0.653CysArg: 0.653 ± 0.014	0.495CysSer: 0.495 ± 0.011	0.539CysThr: 0.539 ± 0.014	0.714CysVal: 0.714 ± 0.014	0.169CysTrp: 0.169 ± 0.008	0.203CysTyr: 0.203 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	7.528AspAla: 7.528 ± 0.051	0.481AspCys: 0.481 ± 0.013	3.819AspAsp: 3.819 ± 0.036	3.738AspGlu: 3.738 ± 0.041	1.726AspPhe: 1.726 ± 0.023	6.366AspGly: 6.366 ± 0.042	1.535AspHis: 1.535 ± 0.021	1.97AspIle: 1.97 ± 0.022	1.206AspLys: 1.206 ± 0.024	6.583AspLeu: 6.583 ± 0.054	0.863AspMet: 0.863 ± 0.016	1.345AspAsn: 1.345 ± 0.023	4.443AspPro: 4.443 ± 0.039	2.066AspGln: 2.066 ± 0.025	4.949AspArg: 4.949 ± 0.049	2.701AspSer: 2.701 ± 0.031	3.235AspThr: 3.235 ± 0.035	5.432AspVal: 5.432 ± 0.043	1.01AspTrp: 1.01 ± 0.016	1.32AspTyr: 1.32 ± 0.022	0.0AspXaa: 0.0 ± 0.0
Glu	5.906GluAla: 5.906 ± 0.053	0.362GluCys: 0.362 ± 0.01	2.395GluAsp: 2.395 ± 0.027	2.331GluGlu: 2.331 ± 0.035	1.658GluPhe: 1.658 ± 0.019	2.879GluGly: 2.879 ± 0.028	1.59GluHis: 1.59 ± 0.029	2.235GluIle: 2.235 ± 0.029	0.952GluLys: 0.952 ± 0.019	7.172GluLeu: 7.172 ± 0.063	0.834GluMet: 0.834 ± 0.015	0.952GluAsn: 0.952 ± 0.016	3.116GluPro: 3.116 ± 0.038	2.304GluGln: 2.304 ± 0.023	4.524GluArg: 4.524 ± 0.044	2.336GluSer: 2.336 ± 0.028	2.415GluThr: 2.415 ± 0.025	4.339GluVal: 4.339 ± 0.038	0.753GluTrp: 0.753 ± 0.016	0.939GluTyr: 0.939 ± 0.017	0.0GluXaa: 0.0 ± 0.0
Phe	3.879PheAla: 3.879 ± 0.03	0.301PheCys: 0.301 ± 0.01	2.317PheAsp: 2.317 ± 0.029	1.358PheGlu: 1.358 ± 0.022	0.836PhePhe: 0.836 ± 0.016	3.185PheGly: 3.185 ± 0.032	0.664PheHis: 0.664 ± 0.014	0.677PheIle: 0.677 ± 0.013	0.433PheLys: 0.433 ± 0.01	2.561PheLeu: 2.561 ± 0.03	0.392PheMet: 0.392 ± 0.011	0.621PheAsn: 0.621 ± 0.015	1.46PhePro: 1.46 ± 0.024	0.757PheGln: 0.757 ± 0.015	1.829PheArg: 1.829 ± 0.024	1.474PheSer: 1.474 ± 0.021	2.077PheThr: 2.077 ± 0.025	2.537PheVal: 2.537 ± 0.033	0.425PheTrp: 0.425 ± 0.012	0.625PheTyr: 0.625 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	9.588GlyAla: 9.588 ± 0.06	0.87GlyCys: 0.87 ± 0.017	5.274GlyAsp: 5.274 ± 0.043	4.39GlyGlu: 4.39 ± 0.042	2.907GlyPhe: 2.907 ± 0.033	8.17GlyGly: 8.17 ± 0.082	2.154GlyHis: 2.154 ± 0.027	3.498GlyIle: 3.498 ± 0.036	2.304GlyLys: 2.304 ± 0.025	9.198GlyLeu: 9.198 ± 0.059	1.96GlyMet: 1.96 ± 0.026	2.122GlyAsn: 2.122 ± 0.038	4.601GlyPro: 4.601 ± 0.041	3.04GlyGln: 3.04 ± 0.035	6.821GlyArg: 6.821 ± 0.048	5.207GlySer: 5.207 ± 0.041	5.611GlyThr: 5.611 ± 0.049	7.955GlyVal: 7.955 ± 0.055	1.77GlyTrp: 1.77 ± 0.025	2.387GlyTyr: 2.387 ± 0.029	0.0GlyXaa: 0.0 ± 0.0
His	2.653HisAla: 2.653 ± 0.03	0.229HisCys: 0.229 ± 0.009	1.453HisAsp: 1.453 ± 0.023	1.175HisGlu: 1.175 ± 0.019	0.631HisPhe: 0.631 ± 0.013	2.328HisGly: 2.328 ± 0.025	0.681HisHis: 0.681 ± 0.017	0.672HisIle: 0.672 ± 0.014	0.345HisLys: 0.345 ± 0.009	2.347HisLeu: 2.347 ± 0.028	0.346HisMet: 0.346 ± 0.01	0.506HisAsn: 0.506 ± 0.014	1.615HisPro: 1.615 ± 0.024	0.721HisGln: 0.721 ± 0.016	2.031HisArg: 2.031 ± 0.027	1.072HisSer: 1.072 ± 0.019	1.261HisThr: 1.261 ± 0.019	1.981HisVal: 1.981 ± 0.025	0.397HisTrp: 0.397 ± 0.011	0.512HisTyr: 0.512 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	5.395IleAla: 5.395 ± 0.047	0.287IleCys: 0.287 ± 0.01	2.587IleAsp: 2.587 ± 0.024	2.053IleGlu: 2.053 ± 0.026	0.705IlePhe: 0.705 ± 0.016	3.958IleGly: 3.958 ± 0.038	0.615IleHis: 0.615 ± 0.014	0.948IleIle: 0.948 ± 0.018	0.685IleLys: 0.685 ± 0.014	2.374IleLeu: 2.374 ± 0.027	0.452IleMet: 0.452 ± 0.012	0.814IleAsn: 0.814 ± 0.015	1.867IlePro: 1.867 ± 0.026	0.844IleGln: 0.844 ± 0.016	2.388IleArg: 2.388 ± 0.031	1.886IleSer: 1.886 ± 0.026	2.611IleThr: 2.611 ± 0.032	3.22IleVal: 3.22 ± 0.036	0.408IleTrp: 0.408 ± 0.012	0.58IleTyr: 0.58 ± 0.013	0.0IleXaa: 0.0 ± 0.0
Lys	2.671LysAla: 2.671 ± 0.03	0.137LysCys: 0.137 ± 0.007	1.04LysAsp: 1.04 ± 0.019	0.781LysGlu: 0.781 ± 0.017	0.524LysPhe: 0.524 ± 0.011	1.394LysGly: 1.394 ± 0.02	0.446LysHis: 0.446 ± 0.012	0.873LysIle: 0.873 ± 0.018	0.448LysLys: 0.448 ± 0.013	2.109LysLeu: 2.109 ± 0.028	0.361LysMet: 0.361 ± 0.011	0.431LysAsn: 0.431 ± 0.012	1.368LysPro: 1.368 ± 0.022	0.713LysGln: 0.713 ± 0.016	1.307LysArg: 1.307 ± 0.021	1.041LysSer: 1.041 ± 0.018	1.195LysThr: 1.195 ± 0.019	1.866LysVal: 1.866 ± 0.027	0.294LysTrp: 0.294 ± 0.01	0.402LysTyr: 0.402 ± 0.012	0.0LysXaa: 0.0 ± 0.0
Leu	16.018LeuAla: 16.018 ± 0.098	0.891LeuCys: 0.891 ± 0.017	7.017LeuAsp: 7.017 ± 0.05	4.068LeuGlu: 4.068 ± 0.038	2.653LeuPhe: 2.653 ± 0.03	9.2LeuGly: 9.2 ± 0.062	2.365LeuHis: 2.365 ± 0.029	3.483LeuIle: 3.483 ± 0.037	1.605LeuLys: 1.605 ± 0.024	10.978LeuLeu: 10.978 ± 0.086	1.511LeuMet: 1.511 ± 0.021	1.93LeuAsn: 1.93 ± 0.023	6.519LeuPro: 6.519 ± 0.051	2.165LeuGln: 2.165 ± 0.027	8.727LeuArg: 8.727 ± 0.06	5.716LeuSer: 5.716 ± 0.042	6.911LeuThr: 6.911 ± 0.045	9.798LeuVal: 9.798 ± 0.066	1.36LeuTrp: 1.36 ± 0.024	1.741LeuTyr: 1.741 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	2.246MetAla: 2.246 ± 0.023	0.131MetCys: 0.131 ± 0.006	0.866MetAsp: 0.866 ± 0.016	0.624MetGlu: 0.624 ± 0.013	0.505MetPhe: 0.505 ± 0.011	1.207MetGly: 1.207 ± 0.018	0.379MetHis: 0.379 ± 0.01	0.775MetIle: 0.775 ± 0.015	0.343MetLys: 0.343 ± 0.01	1.842MetLeu: 1.842 ± 0.024	0.294MetMet: 0.294 ± 0.01	0.412MetAsn: 0.412 ± 0.012	1.153MetPro: 1.153 ± 0.018	0.451MetGln: 0.451 ± 0.01	1.448MetArg: 1.448 ± 0.02	1.283MetSer: 1.283 ± 0.019	1.583MetThr: 1.583 ± 0.017	1.456MetVal: 1.456 ± 0.02	0.227MetTrp: 0.227 ± 0.008	0.287MetTyr: 0.287 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	2.706AsnAla: 2.706 ± 0.033	0.21AsnCys: 0.21 ± 0.008	1.179AsnAsp: 1.179 ± 0.018	0.868AsnGlu: 0.868 ± 0.017	0.598AsnPhe: 0.598 ± 0.012	2.497AsnGly: 2.497 ± 0.036	0.465AsnHis: 0.465 ± 0.013	0.691AsnIle: 0.691 ± 0.012	0.41AsnLys: 0.41 ± 0.011	2.025AsnLeu: 2.025 ± 0.027	0.337AsnMet: 0.337 ± 0.01	0.647AsnAsn: 0.647 ± 0.021	1.666AsnPro: 1.666 ± 0.026	0.743AsnGln: 0.743 ± 0.018	1.441AsnArg: 1.441 ± 0.02	1.201AsnSer: 1.201 ± 0.021	1.388AsnThr: 1.388 ± 0.028	1.643AsnVal: 1.643 ± 0.026	0.386AsnTrp: 0.386 ± 0.011	0.523AsnTyr: 0.523 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	8.016ProAla: 8.016 ± 0.053	0.371ProCys: 0.371 ± 0.008	4.411ProAsp: 4.411 ± 0.04	3.474ProGlu: 3.474 ± 0.037	1.541ProPhe: 1.541 ± 0.022	5.73ProGly: 5.73 ± 0.04	1.232ProHis: 1.232 ± 0.021	1.743ProIle: 1.743 ± 0.023	1.133ProLys: 1.133 ± 0.022	5.086ProLeu: 5.086 ± 0.04	1.09ProMet: 1.09 ± 0.017	1.345ProAsn: 1.345 ± 0.022	3.38ProPro: 3.38 ± 0.053	1.781ProGln: 1.781 ± 0.026	3.387ProArg: 3.387 ± 0.035	3.268ProSer: 3.268 ± 0.035	3.762ProThr: 3.762 ± 0.036	5.382ProVal: 5.382 ± 0.036	0.904ProTrp: 0.904 ± 0.015	1.173ProTyr: 1.173 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	4.18GlnAla: 4.18 ± 0.041	0.234GlnCys: 0.234 ± 0.007	1.415GlnAsp: 1.415 ± 0.021	1.163GlnGlu: 1.163 ± 0.021	0.919GlnPhe: 0.919 ± 0.018	2.147GlnGly: 2.147 ± 0.03	0.845GlnHis: 0.845 ± 0.018	1.204GlnIle: 1.204 ± 0.02	0.523GlnLys: 0.523 ± 0.013	3.888GlnLeu: 3.888 ± 0.037	0.515GlnMet: 0.515 ± 0.011	0.676GlnAsn: 0.676 ± 0.014	2.044GlnPro: 2.044 ± 0.03	1.577GlnGln: 1.577 ± 0.031	2.676GlnArg: 2.676 ± 0.031	1.44GlnSer: 1.44 ± 0.021	1.594GlnThr: 1.594 ± 0.027	2.898GlnVal: 2.898 ± 0.03	0.614GlnTrp: 0.614 ± 0.016	0.644GlnTyr: 0.644 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	8.819ArgAla: 8.819 ± 0.051	0.665ArgCys: 0.665 ± 0.016	4.234ArgAsp: 4.234 ± 0.043	4.018ArgGlu: 4.018 ± 0.04	2.378ArgPhe: 2.378 ± 0.025	5.174ArgGly: 5.174 ± 0.039	2.019ArgHis: 2.019 ± 0.028	3.091ArgIle: 3.091 ± 0.029	1.549ArgLys: 1.549 ± 0.024	8.753ArgLeu: 8.753 ± 0.065	1.733ArgMet: 1.733 ± 0.024	1.499ArgAsn: 1.499 ± 0.021	4.467ArgPro: 4.467 ± 0.041	2.642ArgGln: 2.642 ± 0.034	7.384ArgArg: 7.384 ± 0.055	3.941ArgSer: 3.941 ± 0.035	4.551ArgThr: 4.551 ± 0.045	5.747ArgVal: 5.747 ± 0.049	1.442ArgTrp: 1.442 ± 0.023	1.764ArgTyr: 1.764 ± 0.025	0.0ArgXaa: 0.0 ± 0.0
Ser	6.644SerAla: 6.644 ± 0.055	0.488SerCys: 0.488 ± 0.012	2.944SerAsp: 2.944 ± 0.033	2.18SerGlu: 2.18 ± 0.024	1.578SerPhe: 1.578 ± 0.023	5.556SerGly: 5.556 ± 0.05	1.028SerHis: 1.028 ± 0.018	1.736SerIle: 1.736 ± 0.026	1.033SerLys: 1.033 ± 0.018	4.973SerLeu: 4.973 ± 0.038	1.177SerMet: 1.177 ± 0.018	1.167SerAsn: 1.167 ± 0.021	3.142SerPro: 3.142 ± 0.029	1.516SerGln: 1.516 ± 0.026	3.733SerArg: 3.733 ± 0.035	3.103SerSer: 3.103 ± 0.035	3.726SerThr: 3.726 ± 0.039	4.657SerVal: 4.657 ± 0.033	1.054SerTrp: 1.054 ± 0.019	1.329SerTyr: 1.329 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	8.587ThrAla: 8.587 ± 0.052	0.522ThrCys: 0.522 ± 0.013	3.711ThrAsp: 3.711 ± 0.041	2.985ThrGlu: 2.985 ± 0.031	1.747ThrPhe: 1.747 ± 0.023	6.325ThrGly: 6.325 ± 0.055	1.133ThrHis: 1.133 ± 0.019	2.221ThrIle: 2.221 ± 0.024	1.225ThrLys: 1.225 ± 0.021	5.742ThrLeu: 5.742 ± 0.042	1.061ThrMet: 1.061 ± 0.018	1.349ThrAsn: 1.349 ± 0.022	4.045ThrPro: 4.045 ± 0.039	1.633ThrGln: 1.633 ± 0.024	3.715ThrArg: 3.715 ± 0.037	3.622ThrSer: 3.622 ± 0.041	4.643ThrThr: 4.643 ± 0.06	6.557ThrVal: 6.557 ± 0.054	1.037ThrTrp: 1.037 ± 0.018	1.351ThrTyr: 1.351 ± 0.026	0.0ThrXaa: 0.0 ± 0.0
Val	11.735ValAla: 11.735 ± 0.078	0.748ValCys: 0.748 ± 0.014	6.171ValAsp: 6.171 ± 0.045	4.699ValGlu: 4.699 ± 0.043	2.581ValPhe: 2.581 ± 0.028	7.148ValGly: 7.148 ± 0.054	2.089ValHis: 2.089 ± 0.027	3.241ValIle: 3.241 ± 0.03	1.593ValLys: 1.593 ± 0.02	10.193ValLeu: 10.193 ± 0.067	1.286ValMet: 1.286 ± 0.019	1.991ValAsn: 1.991 ± 0.024	5.02ValPro: 5.02 ± 0.042	2.471ValGln: 2.471 ± 0.027	6.719ValArg: 6.719 ± 0.052	4.809ValSer: 4.809 ± 0.044	6.004ValThr: 6.004 ± 0.049	8.791ValVal: 8.791 ± 0.066	1.167ValTrp: 1.167 ± 0.018	1.586ValTyr: 1.586 ± 0.022	0.0ValXaa: 0.0 ± 0.0
Trp	1.671TrpAla: 1.671 ± 0.024	0.159TrpCys: 0.159 ± 0.007	0.852TrpAsp: 0.852 ± 0.017	0.643TrpGlu: 0.643 ± 0.015	0.544TrpPhe: 0.544 ± 0.016	1.026TrpGly: 1.026 ± 0.018	0.453TrpHis: 0.453 ± 0.012	0.598TrpIle: 0.598 ± 0.013	0.277TrpLys: 0.277 ± 0.01	2.038TrpLeu: 2.038 ± 0.025	0.307TrpMet: 0.307 ± 0.01	0.444TrpAsn: 0.444 ± 0.013	0.899TrpPro: 0.899 ± 0.018	0.753TrpGln: 0.753 ± 0.017	1.429TrpArg: 1.429 ± 0.02	1.035TrpSer: 1.035 ± 0.019	1.157TrpThr: 1.157 ± 0.02	1.059TrpVal: 1.059 ± 0.016	0.371TrpTrp: 0.371 ± 0.011	0.35TrpTyr: 0.35 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.414TyrAla: 2.414 ± 0.026	0.186TyrCys: 0.186 ± 0.007	1.448TyrAsp: 1.448 ± 0.031	1.036TyrGlu: 1.036 ± 0.019	0.644TyrPhe: 0.644 ± 0.014	2.005TyrGly: 2.005 ± 0.028	0.477TyrHis: 0.477 ± 0.012	0.474TyrIle: 0.474 ± 0.013	0.348TyrLys: 0.348 ± 0.012	2.254TyrLeu: 2.254 ± 0.027	0.233TyrMet: 0.233 ± 0.008	0.506TyrAsn: 0.506 ± 0.015	1.098TyrPro: 1.098 ± 0.02	0.788TyrGln: 0.788 ± 0.015	1.842TyrArg: 1.842 ± 0.024	1.082TyrSer: 1.082 ± 0.022	1.237TyrThr: 1.237 ± 0.023	1.689TyrVal: 1.689 ± 0.022	0.387TyrTrp: 0.387 ± 0.012	0.511TyrTyr: 0.511 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 10965 proteins (3593623 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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