Amino acid dipepetide frequency for Soil-borne wheat mosaic virus (strain United States/Nebraska/1981) (SBWMV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.469AlaAla: 5.469 ± 1.195
0.0AlaCys: 0.0 ± 0.0
3.742AlaAsp: 3.742 ± 0.998
5.181AlaGlu: 5.181 ± 1.672
2.303AlaPhe: 2.303 ± 0.367
2.015AlaGly: 2.015 ± 1.035
1.727AlaHis: 1.727 ± 0.457
3.454AlaIle: 3.454 ± 0.644
5.181AlaLys: 5.181 ± 1.062
8.636AlaLeu: 8.636 ± 0.785
2.303AlaMet: 2.303 ± 0.513
1.439AlaAsn: 1.439 ± 0.631
2.591AlaPro: 2.591 ± 0.615
3.454AlaGln: 3.454 ± 0.946
2.879AlaArg: 2.879 ± 0.976
4.03AlaSer: 4.03 ± 0.288
6.045AlaThr: 6.045 ± 0.925
8.348AlaVal: 8.348 ± 1.746
0.864AlaTrp: 0.864 ± 0.531
3.166AlaTyr: 3.166 ± 1.458
0.0AlaXaa: 0.0 ± 0.0
Cys
0.864CysAla: 0.864 ± 0.458
0.576CysCys: 0.576 ± 0.341
2.303CysAsp: 2.303 ± 0.513
0.864CysGlu: 0.864 ± 0.512
0.864CysPhe: 0.864 ± 0.338
2.591CysGly: 2.591 ± 1.373
0.0CysHis: 0.0 ± 0.0
1.439CysIle: 1.439 ± 0.435
0.576CysLys: 0.576 ± 0.341
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.576CysAsn: 0.576 ± 0.244
0.576CysPro: 0.576 ± 0.447
0.576CysGln: 0.576 ± 0.341
1.439CysArg: 1.439 ± 0.435
0.288CysSer: 0.288 ± 0.171
0.576CysThr: 0.576 ± 0.244
1.727CysVal: 1.727 ± 0.869
0.0CysTrp: 0.0 ± 0.0
1.439CysTyr: 1.439 ± 0.727
0.0CysXaa: 0.0 ± 0.0
Asp
3.742AspAla: 3.742 ± 1.345
1.151AspCys: 1.151 ± 0.527
4.03AspAsp: 4.03 ± 1.51
4.893AspGlu: 4.893 ± 0.911
3.742AspPhe: 3.742 ± 0.841
4.606AspGly: 4.606 ± 0.839
1.151AspHis: 1.151 ± 0.527
2.015AspIle: 2.015 ± 1.195
2.879AspLys: 2.879 ± 0.689
7.196AspLeu: 7.196 ± 1.549
0.864AspMet: 0.864 ± 0.394
1.727AspAsn: 1.727 ± 1.024
1.151AspPro: 1.151 ± 0.683
2.303AspGln: 2.303 ± 1.277
3.454AspArg: 3.454 ± 1.422
6.333AspSer: 6.333 ± 0.708
2.015AspThr: 2.015 ± 0.369
6.045AspVal: 6.045 ± 1.216
0.0AspTrp: 0.0 ± 0.0
1.727AspTyr: 1.727 ± 0.578
0.0AspXaa: 0.0 ± 0.0
Glu
5.757GluAla: 5.757 ± 0.81
1.439GluCys: 1.439 ± 0.518
4.606GluAsp: 4.606 ± 1.816
5.757GluGlu: 5.757 ± 1.365
2.303GluPhe: 2.303 ± 0.789
2.303GluGly: 2.303 ± 1.72
0.288GluHis: 0.288 ± 0.171
4.893GluIle: 4.893 ± 0.955
6.045GluLys: 6.045 ± 2.037
7.772GluLeu: 7.772 ± 0.337
1.151GluMet: 1.151 ± 1.137
2.879GluAsn: 2.879 ± 1.342
1.151GluPro: 1.151 ± 0.9
2.591GluGln: 2.591 ± 0.694
4.03GluArg: 4.03 ± 0.688
6.333GluSer: 6.333 ± 0.336
2.591GluThr: 2.591 ± 1.205
6.621GluVal: 6.621 ± 1.26
0.864GluTrp: 0.864 ± 0.527
0.864GluTyr: 0.864 ± 0.512
0.0GluXaa: 0.0 ± 0.0
Phe
2.591PheAla: 2.591 ± 0.646
1.439PheCys: 1.439 ± 0.518
2.879PheAsp: 2.879 ± 1.064
4.606PheGlu: 4.606 ± 0.858
2.015PhePhe: 2.015 ± 0.578
2.879PheGly: 2.879 ± 0.586
0.864PheHis: 0.864 ± 0.458
0.864PheIle: 0.864 ± 0.527
2.015PheLys: 2.015 ± 0.438
3.166PheLeu: 3.166 ± 1.263
1.439PheMet: 1.439 ± 0.631
1.727PheAsn: 1.727 ± 0.41
1.151PhePro: 1.151 ± 0.407
0.864PheGln: 0.864 ± 0.527
1.151PheArg: 1.151 ± 0.407
2.879PheSer: 2.879 ± 0.45
1.727PheThr: 1.727 ± 0.589
4.318PheVal: 4.318 ± 0.436
0.0PheTrp: 0.0 ± 0.0
0.288PheTyr: 0.288 ± 0.171
0.0PheXaa: 0.0 ± 0.0
Gly
5.181GlyAla: 5.181 ± 2.009
0.576GlyCys: 0.576 ± 0.244
3.454GlyAsp: 3.454 ± 0.43
4.318GlyGlu: 4.318 ± 2.003
1.439GlyPhe: 1.439 ± 0.635
5.181GlyGly: 5.181 ± 1.974
0.864GlyHis: 0.864 ± 0.531
1.151GlyIle: 1.151 ± 0.407
4.606GlyLys: 4.606 ± 0.995
2.303GlyLeu: 2.303 ± 0.841
1.439GlyMet: 1.439 ± 0.42
2.591GlyAsn: 2.591 ± 0.623
2.303GlyPro: 2.303 ± 0.571
2.303GlyGln: 2.303 ± 0.847
2.591GlyArg: 2.591 ± 0.792
3.454GlySer: 3.454 ± 0.63
4.606GlyThr: 4.606 ± 0.734
6.333GlyVal: 6.333 ± 2.577
0.0GlyTrp: 0.0 ± 0.0
4.03GlyTyr: 4.03 ± 1.939
0.0GlyXaa: 0.0 ± 0.0
His
2.015HisAla: 2.015 ± 0.706
0.864HisCys: 0.864 ± 0.458
0.576HisAsp: 0.576 ± 0.447
1.151HisGlu: 1.151 ± 0.683
1.439HisPhe: 1.439 ± 0.554
0.576HisGly: 0.576 ± 0.244
0.288HisHis: 0.288 ± 0.306
0.864HisIle: 0.864 ± 0.289
0.576HisLys: 0.576 ± 0.244
2.015HisLeu: 2.015 ± 0.578
0.0HisMet: 0.0 ± 0.0
1.439HisAsn: 1.439 ± 0.631
0.576HisPro: 0.576 ± 0.592
0.0HisGln: 0.0 ± 0.0
0.864HisArg: 0.864 ± 0.458
1.727HisSer: 1.727 ± 0.711
1.439HisThr: 1.439 ± 1.168
2.015HisVal: 2.015 ± 0.64
0.0HisTrp: 0.0 ± 0.0
0.576HisTyr: 0.576 ± 0.348
0.0HisXaa: 0.0 ± 0.0
Ile
0.864IleAla: 0.864 ± 0.919
0.576IleCys: 0.576 ± 0.341
2.879IleAsp: 2.879 ± 1.261
4.318IleGlu: 4.318 ± 0.509
3.454IlePhe: 3.454 ± 0.961
1.151IleGly: 1.151 ± 0.407
0.864IleHis: 0.864 ± 0.527
2.591IleIle: 2.591 ± 0.868
2.303IleLys: 2.303 ± 0.896
3.742IleLeu: 3.742 ± 0.314
0.0IleMet: 0.0 ± 0.0
1.151IleAsn: 1.151 ± 0.291
2.015IlePro: 2.015 ± 1.065
1.151IleGln: 1.151 ± 0.407
3.742IleArg: 3.742 ± 0.631
3.742IleSer: 3.742 ± 0.858
3.166IleThr: 3.166 ± 0.818
4.318IleVal: 4.318 ± 1.496
0.0IleTrp: 0.0 ± 0.0
1.439IleTyr: 1.439 ± 0.853
0.0IleXaa: 0.0 ± 0.0
Lys
4.606LysAla: 4.606 ± 0.876
1.439LysCys: 1.439 ± 0.889
3.742LysAsp: 3.742 ± 0.926
4.606LysGlu: 4.606 ± 1.243
2.591LysPhe: 2.591 ± 0.992
4.318LysGly: 4.318 ± 1.248
1.727LysHis: 1.727 ± 0.767
3.454LysIle: 3.454 ± 0.505
4.318LysLys: 4.318 ± 1.905
7.196LysLeu: 7.196 ± 1.108
1.439LysMet: 1.439 ± 0.615
2.303LysAsn: 2.303 ± 0.523
2.015LysPro: 2.015 ± 0.873
1.727LysGln: 1.727 ± 0.537
6.333LysArg: 6.333 ± 1.0
3.742LysSer: 3.742 ± 0.859
4.03LysThr: 4.03 ± 0.8
4.318LysVal: 4.318 ± 1.339
1.727LysTrp: 1.727 ± 0.926
3.454LysTyr: 3.454 ± 0.547
0.288LysXaa: 0.288 ± 0.171
Leu
5.181LeuAla: 5.181 ± 1.056
1.439LeuCys: 1.439 ± 0.554
5.181LeuAsp: 5.181 ± 1.502
4.606LeuGlu: 4.606 ± 0.7
2.591LeuPhe: 2.591 ± 1.205
6.045LeuGly: 6.045 ± 2.36
1.727LeuHis: 1.727 ± 0.779
2.879LeuIle: 2.879 ± 1.015
5.757LeuLys: 5.757 ± 0.753
8.348LeuLeu: 8.348 ± 1.547
4.318LeuMet: 4.318 ± 1.032
4.893LeuAsn: 4.893 ± 1.255
3.742LeuPro: 3.742 ± 0.716
4.318LeuGln: 4.318 ± 0.724
6.333LeuArg: 6.333 ± 1.022
7.484LeuSer: 7.484 ± 2.111
6.333LeuThr: 6.333 ± 1.059
3.454LeuVal: 3.454 ± 0.946
2.303LeuTrp: 2.303 ± 0.815
2.015LeuTyr: 2.015 ± 0.588
0.0LeuXaa: 0.0 ± 0.0
Met
3.742MetAla: 3.742 ± 1.548
0.288MetCys: 0.288 ± 0.382
1.727MetAsp: 1.727 ± 1.059
0.864MetGlu: 0.864 ± 0.338
1.439MetPhe: 1.439 ± 0.853
0.576MetGly: 0.576 ± 0.764
0.576MetHis: 0.576 ± 0.348
1.439MetIle: 1.439 ± 0.518
4.03MetLys: 4.03 ± 1.112
2.303MetLeu: 2.303 ± 1.211
0.576MetMet: 0.576 ± 0.348
2.591MetAsn: 2.591 ± 0.531
1.151MetPro: 1.151 ± 0.527
1.151MetGln: 1.151 ± 0.697
0.288MetArg: 0.288 ± 0.306
2.591MetSer: 2.591 ± 1.011
0.864MetThr: 0.864 ± 0.512
0.576MetVal: 0.576 ± 0.244
0.288MetTrp: 0.288 ± 0.171
0.576MetTyr: 0.576 ± 0.244
0.0MetXaa: 0.0 ± 0.0
Asn
5.181AsnAla: 5.181 ± 1.565
1.727AsnCys: 1.727 ± 0.767
2.591AsnAsp: 2.591 ± 0.883
3.454AsnGlu: 3.454 ± 1.178
2.015AsnPhe: 2.015 ± 0.438
2.591AsnGly: 2.591 ± 0.903
0.0AsnHis: 0.0 ± 0.0
0.576AsnIle: 0.576 ± 0.764
3.166AsnLys: 3.166 ± 1.611
2.879AsnLeu: 2.879 ± 0.45
1.439AsnMet: 1.439 ± 0.615
0.576AsnAsn: 0.576 ± 0.341
0.576AsnPro: 0.576 ± 0.341
1.439AsnGln: 1.439 ± 0.631
2.879AsnArg: 2.879 ± 0.668
1.727AsnSer: 1.727 ± 0.41
2.015AsnThr: 2.015 ± 0.873
3.166AsnVal: 3.166 ± 1.592
1.151AsnTrp: 1.151 ± 0.497
1.151AsnTyr: 1.151 ± 0.683
0.0AsnXaa: 0.0 ± 0.0
Pro
2.303ProAla: 2.303 ± 1.283
0.576ProCys: 0.576 ± 0.244
1.727ProAsp: 1.727 ± 0.57
3.166ProGlu: 3.166 ± 1.485
0.288ProPhe: 0.288 ± 0.171
3.742ProGly: 3.742 ± 0.966
0.576ProHis: 0.576 ± 0.348
0.864ProIle: 0.864 ± 0.512
3.742ProLys: 3.742 ± 1.802
2.591ProLeu: 2.591 ± 1.218
1.439ProMet: 1.439 ± 0.337
0.576ProAsn: 0.576 ± 0.341
1.439ProPro: 1.439 ± 0.435
0.864ProGln: 0.864 ± 0.338
1.151ProArg: 1.151 ± 0.827
0.864ProSer: 0.864 ± 0.527
1.151ProThr: 1.151 ± 0.497
2.591ProVal: 2.591 ± 0.894
0.0ProTrp: 0.0 ± 0.0
1.151ProTyr: 1.151 ± 0.291
0.0ProXaa: 0.0 ± 0.0
Gln
3.166GlnAla: 3.166 ± 0.414
0.576GlnCys: 0.576 ± 0.341
2.303GlnAsp: 2.303 ± 0.867
1.151GlnGlu: 1.151 ± 0.497
0.576GlnPhe: 0.576 ± 0.244
2.591GlnGly: 2.591 ± 0.774
0.864GlnHis: 0.864 ± 0.527
3.166GlnIle: 3.166 ± 1.631
2.591GlnLys: 2.591 ± 0.894
2.879GlnLeu: 2.879 ± 0.716
0.864GlnMet: 0.864 ± 0.394
0.864GlnAsn: 0.864 ± 0.527
1.151GlnPro: 1.151 ± 0.497
1.727GlnGln: 1.727 ± 1.024
3.742GlnArg: 3.742 ± 1.539
2.303GlnSer: 2.303 ± 0.96
4.318GlnThr: 4.318 ± 2.401
2.015GlnVal: 2.015 ± 1.174
0.0GlnTrp: 0.0 ± 0.0
0.864GlnTyr: 0.864 ± 0.512
0.0GlnXaa: 0.0 ± 0.0
Arg
6.333ArgAla: 6.333 ± 1.281
0.864ArgCys: 0.864 ± 0.289
3.742ArgAsp: 3.742 ± 1.363
3.166ArgGlu: 3.166 ± 0.775
2.591ArgPhe: 2.591 ± 0.691
4.03ArgGly: 4.03 ± 1.239
1.439ArgHis: 1.439 ± 0.589
3.742ArgIle: 3.742 ± 1.524
4.893ArgLys: 4.893 ± 1.244
7.196ArgLeu: 7.196 ± 1.802
1.151ArgMet: 1.151 ± 0.407
3.166ArgAsn: 3.166 ± 0.414
0.576ArgPro: 0.576 ± 0.341
2.015ArgGln: 2.015 ± 1.065
3.454ArgArg: 3.454 ± 1.425
4.893ArgSer: 4.893 ± 1.349
4.03ArgThr: 4.03 ± 0.924
2.015ArgVal: 2.015 ± 0.873
0.576ArgTrp: 0.576 ± 0.341
0.864ArgTyr: 0.864 ± 0.338
0.0ArgXaa: 0.0 ± 0.0
Ser
4.318SerAla: 4.318 ± 0.943
0.576SerCys: 0.576 ± 0.62
4.893SerAsp: 4.893 ± 1.169
3.742SerGlu: 3.742 ± 0.831
4.03SerPhe: 4.03 ± 1.093
3.166SerGly: 3.166 ± 0.757
0.288SerHis: 0.288 ± 0.171
3.166SerIle: 3.166 ± 0.567
4.606SerLys: 4.606 ± 0.348
4.893SerLeu: 4.893 ± 1.562
2.303SerMet: 2.303 ± 0.51
2.303SerAsn: 2.303 ± 0.528
2.015SerPro: 2.015 ± 0.435
4.03SerGln: 4.03 ± 1.093
4.318SerArg: 4.318 ± 0.798
5.757SerSer: 5.757 ± 0.47
5.181SerThr: 5.181 ± 0.588
6.908SerVal: 6.908 ± 1.528
1.727SerTrp: 1.727 ± 0.457
3.166SerTyr: 3.166 ± 0.892
0.288SerXaa: 0.288 ± 0.306
Thr
2.591ThrAla: 2.591 ± 0.646
0.864ThrCys: 0.864 ± 0.8
2.591ThrAsp: 2.591 ± 0.389
4.606ThrGlu: 4.606 ± 1.466
2.303ThrPhe: 2.303 ± 0.815
3.742ThrGly: 3.742 ± 1.796
2.591ThrHis: 2.591 ± 1.318
1.727ThrIle: 1.727 ± 0.779
5.757ThrLys: 5.757 ± 1.069
4.606ThrLeu: 4.606 ± 1.294
2.303ThrMet: 2.303 ± 0.722
1.727ThrAsn: 1.727 ± 1.045
1.727ThrPro: 1.727 ± 0.864
3.742ThrGln: 3.742 ± 2.462
4.606ThrArg: 4.606 ± 1.733
5.181ThrSer: 5.181 ± 0.843
5.757ThrThr: 5.757 ± 1.78
6.333ThrVal: 6.333 ± 0.276
0.864ThrTrp: 0.864 ± 0.512
1.439ThrTyr: 1.439 ± 0.853
0.0ThrXaa: 0.0 ± 0.0
Val
5.181ValAla: 5.181 ± 0.843
1.151ValCys: 1.151 ± 0.527
6.621ValAsp: 6.621 ± 1.503
6.908ValGlu: 6.908 ± 0.922
2.015ValPhe: 2.015 ± 0.742
4.606ValGly: 4.606 ± 1.166
2.303ValHis: 2.303 ± 0.803
3.454ValIle: 3.454 ± 0.937
3.166ValLys: 3.166 ± 1.094
6.045ValLeu: 6.045 ± 1.651
3.742ValMet: 3.742 ± 1.646
3.742ValAsn: 3.742 ± 0.404
3.742ValPro: 3.742 ± 0.735
1.727ValGln: 1.727 ± 0.578
4.318ValArg: 4.318 ± 0.835
5.757ValSer: 5.757 ± 0.701
5.469ValThr: 5.469 ± 1.572
6.333ValVal: 6.333 ± 1.878
0.864ValTrp: 0.864 ± 0.512
2.879ValTyr: 2.879 ± 0.473
0.0ValXaa: 0.0 ± 0.0
Trp
1.151TrpAla: 1.151 ± 0.683
0.288TrpCys: 0.288 ± 0.171
0.0TrpAsp: 0.0 ± 0.0
1.727TrpGlu: 1.727 ± 0.589
0.0TrpPhe: 0.0 ± 0.0
0.288TrpGly: 0.288 ± 0.171
0.0TrpHis: 0.0 ± 0.0
0.576TrpIle: 0.576 ± 0.341
0.576TrpLys: 0.576 ± 0.341
1.439TrpLeu: 1.439 ± 1.532
0.576TrpMet: 0.576 ± 0.319
0.576TrpAsn: 0.576 ± 0.341
0.0TrpPro: 0.0 ± 0.0
1.151TrpGln: 1.151 ± 0.622
0.288TrpArg: 0.288 ± 0.499
0.864TrpSer: 0.864 ± 0.289
1.151TrpThr: 1.151 ± 1.086
0.288TrpVal: 0.288 ± 0.171
0.288TrpTrp: 0.288 ± 0.171
0.864TrpTyr: 0.864 ± 0.512
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.591TyrAla: 2.591 ± 0.901
0.864TyrCys: 0.864 ± 0.458
1.439TyrAsp: 1.439 ± 0.631
1.151TyrGlu: 1.151 ± 0.497
0.864TyrPhe: 0.864 ± 0.527
1.727TyrGly: 1.727 ± 0.711
0.864TyrHis: 0.864 ± 0.527
1.151TyrIle: 1.151 ± 0.622
2.591TyrLys: 2.591 ± 0.711
3.742TyrLeu: 3.742 ± 1.583
0.0TyrMet: 0.0 ± 0.0
3.454TyrAsn: 3.454 ± 1.702
1.151TyrPro: 1.151 ± 0.488
0.576TyrGln: 0.576 ± 0.341
2.303TyrArg: 2.303 ± 0.803
2.015TyrSer: 2.015 ± 1.356
2.591TyrThr: 2.591 ± 1.132
2.303TyrVal: 2.303 ± 0.754
0.576TyrTrp: 0.576 ± 0.45
1.727TyrTyr: 1.727 ± 0.711
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.576XaaArg: 0.576 ± 0.244
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (3475 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski