Amino acid dipepetide frequency for Venturia effusa

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.686AlaAla: 8.686 ± 0.061	1.015AlaCys: 1.015 ± 0.017	4.222AlaAsp: 4.222 ± 0.028	5.289AlaGlu: 5.289 ± 0.042	3.088AlaPhe: 3.088 ± 0.028	5.791AlaGly: 5.791 ± 0.036	1.79AlaHis: 1.79 ± 0.021	4.368AlaIle: 4.368 ± 0.033	4.63AlaLys: 4.63 ± 0.037	7.524AlaLeu: 7.524 ± 0.046	2.025AlaMet: 2.025 ± 0.021	3.055AlaAsn: 3.055 ± 0.028	5.036AlaPro: 5.036 ± 0.045	3.47AlaGln: 3.47 ± 0.032	4.914AlaArg: 4.914 ± 0.033	7.343AlaSer: 7.343 ± 0.049	5.337AlaThr: 5.337 ± 0.036	5.229AlaVal: 5.229 ± 0.037	1.148AlaTrp: 1.148 ± 0.018	2.122AlaTyr: 2.122 ± 0.019	0.0AlaXaa: 0.0 ± 0.0
Cys	0.875CysAla: 0.875 ± 0.015	0.227CysCys: 0.227 ± 0.009	0.632CysAsp: 0.632 ± 0.012	0.61CysGlu: 0.61 ± 0.011	0.497CysPhe: 0.497 ± 0.011	0.906CysGly: 0.906 ± 0.016	0.301CysHis: 0.301 ± 0.007	0.659CysIle: 0.659 ± 0.012	0.574CysLys: 0.574 ± 0.011	1.12CysLeu: 1.12 ± 0.015	0.264CysMet: 0.264 ± 0.007	0.423CysAsn: 0.423 ± 0.01	0.637CysPro: 0.637 ± 0.013	0.413CysGln: 0.413 ± 0.009	0.672CysArg: 0.672 ± 0.014	0.86CysSer: 0.86 ± 0.015	0.698CysThr: 0.698 ± 0.012	0.726CysVal: 0.726 ± 0.012	0.193CysTrp: 0.193 ± 0.007	0.347CysTyr: 0.347 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.71AspAla: 4.71 ± 0.036	0.643AspCys: 0.643 ± 0.013	4.321AspAsp: 4.321 ± 0.047	4.68AspGlu: 4.68 ± 0.039	2.308AspPhe: 2.308 ± 0.022	4.094AspGly: 4.094 ± 0.028	1.286AspHis: 1.286 ± 0.015	3.002AspIle: 3.002 ± 0.027	2.535AspLys: 2.535 ± 0.028	4.994AspLeu: 4.994 ± 0.039	1.335AspMet: 1.335 ± 0.017	1.845AspAsn: 1.845 ± 0.019	3.245AspPro: 3.245 ± 0.027	1.913AspGln: 1.913 ± 0.02	3.015AspArg: 3.015 ± 0.026	4.168AspSer: 4.168 ± 0.033	2.953AspThr: 2.953 ± 0.022	3.682AspVal: 3.682 ± 0.026	0.913AspTrp: 0.913 ± 0.015	1.569AspTyr: 1.569 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	5.546GluAla: 5.546 ± 0.045	0.616GluCys: 0.616 ± 0.013	4.432GluAsp: 4.432 ± 0.033	6.021GluGlu: 6.021 ± 0.06	1.928GluPhe: 1.928 ± 0.021	3.862GluGly: 3.862 ± 0.036	1.472GluHis: 1.472 ± 0.017	3.145GluIle: 3.145 ± 0.026	4.154GluLys: 4.154 ± 0.037	5.149GluLeu: 5.149 ± 0.041	1.596GluMet: 1.596 ± 0.017	2.336GluAsn: 2.336 ± 0.022	2.792GluPro: 2.792 ± 0.029	2.626GluGln: 2.626 ± 0.025	4.051GluArg: 4.051 ± 0.033	4.238GluSer: 4.238 ± 0.038	3.484GluThr: 3.484 ± 0.025	3.624GluVal: 3.624 ± 0.029	0.885GluTrp: 0.885 ± 0.013	1.607GluTyr: 1.607 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	3.127PheAla: 3.127 ± 0.025	0.532PheCys: 0.532 ± 0.01	2.289PheAsp: 2.289 ± 0.024	2.205PheGlu: 2.205 ± 0.021	1.579PhePhe: 1.579 ± 0.021	2.923PheGly: 2.923 ± 0.031	0.856PheHis: 0.856 ± 0.012	1.711PheIle: 1.711 ± 0.021	1.643PheLys: 1.643 ± 0.019	3.29PheLeu: 3.29 ± 0.03	0.797PheMet: 0.797 ± 0.014	1.402PheAsn: 1.402 ± 0.017	1.892PhePro: 1.892 ± 0.02	1.358PheGln: 1.358 ± 0.016	1.876PheArg: 1.876 ± 0.019	2.963PheSer: 2.963 ± 0.024	2.162PheThr: 2.162 ± 0.021	2.322PheVal: 2.322 ± 0.024	0.618PheTrp: 0.618 ± 0.012	1.032PheTyr: 1.032 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	5.237GlyAla: 5.237 ± 0.04	0.823GlyCys: 0.823 ± 0.012	3.576GlyAsp: 3.576 ± 0.03	3.75GlyGlu: 3.75 ± 0.032	2.759GlyPhe: 2.759 ± 0.026	5.923GlyGly: 5.923 ± 0.064	1.664GlyHis: 1.664 ± 0.02	3.549GlyIle: 3.549 ± 0.028	3.811GlyLys: 3.811 ± 0.035	5.929GlyLeu: 5.929 ± 0.041	1.734GlyMet: 1.734 ± 0.022	2.6GlyAsn: 2.6 ± 0.025	3.304GlyPro: 3.304 ± 0.032	2.558GlyGln: 2.558 ± 0.027	4.067GlyArg: 4.067 ± 0.036	5.622GlySer: 5.622 ± 0.039	4.06GlyThr: 4.06 ± 0.031	4.116GlyVal: 4.116 ± 0.034	1.138GlyTrp: 1.138 ± 0.015	2.069GlyTyr: 2.069 ± 0.023	0.0GlyXaa: 0.0 ± 0.0
His	1.866HisAla: 1.866 ± 0.02	0.326HisCys: 0.326 ± 0.008	1.375HisAsp: 1.375 ± 0.017	1.399HisGlu: 1.399 ± 0.015	0.936HisPhe: 0.936 ± 0.013	1.717HisGly: 1.717 ± 0.022	0.833HisHis: 0.833 ± 0.015	1.205HisIle: 1.205 ± 0.015	1.007HisLys: 1.007 ± 0.013	2.131HisLeu: 2.131 ± 0.022	0.462HisMet: 0.462 ± 0.01	0.889HisAsn: 0.889 ± 0.014	1.559HisPro: 1.559 ± 0.02	1.024HisGln: 1.024 ± 0.017	1.469HisArg: 1.469 ± 0.019	1.858HisSer: 1.858 ± 0.02	1.261HisThr: 1.261 ± 0.018	1.443HisVal: 1.443 ± 0.017	0.336HisTrp: 0.336 ± 0.008	0.677HisTyr: 0.677 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.389IleAla: 4.389 ± 0.029	0.711IleCys: 0.711 ± 0.012	2.956IleAsp: 2.956 ± 0.026	3.065IleGlu: 3.065 ± 0.026	1.944IlePhe: 1.944 ± 0.021	3.221IleGly: 3.221 ± 0.028	1.183IleHis: 1.183 ± 0.015	2.491IleIle: 2.491 ± 0.026	2.407IleLys: 2.407 ± 0.024	4.488IleLeu: 4.488 ± 0.038	1.06IleMet: 1.06 ± 0.015	1.821IleAsn: 1.821 ± 0.019	3.07IlePro: 3.07 ± 0.028	1.89IleGln: 1.89 ± 0.018	2.754IleArg: 2.754 ± 0.025	3.885IleSer: 3.885 ± 0.029	2.938IleThr: 2.938 ± 0.029	3.203IleVal: 3.203 ± 0.028	0.72IleTrp: 0.72 ± 0.013	1.357IleTyr: 1.357 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	4.799LysAla: 4.799 ± 0.037	0.527LysCys: 0.527 ± 0.01	3.147LysAsp: 3.147 ± 0.026	3.891LysGlu: 3.891 ± 0.036	1.601LysPhe: 1.601 ± 0.018	3.291LysGly: 3.291 ± 0.027	1.238LysHis: 1.238 ± 0.015	2.6LysIle: 2.6 ± 0.023	3.965LysLys: 3.965 ± 0.049	4.242LysLeu: 4.242 ± 0.033	1.167LysMet: 1.167 ± 0.015	1.917LysAsn: 1.917 ± 0.02	2.915LysPro: 2.915 ± 0.026	2.003LysGln: 2.003 ± 0.024	3.765LysArg: 3.765 ± 0.031	3.892LysSer: 3.892 ± 0.033	3.164LysThr: 3.164 ± 0.029	3.026LysVal: 3.026 ± 0.026	0.743LysTrp: 0.743 ± 0.011	1.383LysTyr: 1.383 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	7.634LeuAla: 7.634 ± 0.043	1.108LeuCys: 1.108 ± 0.017	5.046LeuAsp: 5.046 ± 0.029	5.451LeuGlu: 5.451 ± 0.037	3.17LeuPhe: 3.17 ± 0.032	5.637LeuGly: 5.637 ± 0.038	2.183LeuHis: 2.183 ± 0.023	3.813LeuIle: 3.813 ± 0.032	4.473LeuLys: 4.473 ± 0.032	7.814LeuLeu: 7.814 ± 0.06	1.766LeuMet: 1.766 ± 0.019	3.143LeuAsn: 3.143 ± 0.027	5.444LeuPro: 5.444 ± 0.038	3.698LeuGln: 3.698 ± 0.031	5.459LeuArg: 5.459 ± 0.04	6.96LeuSer: 6.96 ± 0.033	4.773LeuThr: 4.773 ± 0.033	5.083LeuVal: 5.083 ± 0.039	1.116LeuTrp: 1.116 ± 0.017	2.205LeuTyr: 2.205 ± 0.027	0.0LeuXaa: 0.0 ± 0.0
Met	2.264MetAla: 2.264 ± 0.02	0.228MetCys: 0.228 ± 0.006	1.352MetAsp: 1.352 ± 0.015	1.39MetGlu: 1.39 ± 0.017	0.76MetPhe: 0.76 ± 0.014	1.524MetGly: 1.524 ± 0.019	0.487MetHis: 0.487 ± 0.01	1.047MetIle: 1.047 ± 0.013	1.187MetLys: 1.187 ± 0.016	1.851MetLeu: 1.851 ± 0.02	0.609MetMet: 0.609 ± 0.012	0.87MetAsn: 0.87 ± 0.014	1.344MetPro: 1.344 ± 0.018	0.879MetGln: 0.879 ± 0.015	1.269MetArg: 1.269 ± 0.016	1.956MetSer: 1.956 ± 0.018	1.336MetThr: 1.336 ± 0.017	1.306MetVal: 1.306 ± 0.017	0.26MetTrp: 0.26 ± 0.007	0.536MetTyr: 0.536 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.262AsnAla: 3.262 ± 0.027	0.442AsnCys: 0.442 ± 0.009	2.036AsnAsp: 2.036 ± 0.022	2.116AsnGlu: 2.116 ± 0.021	1.424AsnPhe: 1.424 ± 0.014	3.128AsnGly: 3.128 ± 0.028	0.924AsnHis: 0.924 ± 0.013	2.028AsnIle: 2.028 ± 0.019	1.663AsnLys: 1.663 ± 0.02	3.239AsnLeu: 3.239 ± 0.026	0.84AsnMet: 0.84 ± 0.014	1.504AsnAsn: 1.504 ± 0.025	2.428AsnPro: 2.428 ± 0.025	1.402AsnGln: 1.402 ± 0.017	1.909AsnArg: 1.909 ± 0.021	2.916AsnSer: 2.916 ± 0.027	2.236AsnThr: 2.236 ± 0.022	2.315AsnVal: 2.315 ± 0.024	0.562AsnTrp: 0.562 ± 0.012	1.033AsnTyr: 1.033 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	5.371ProAla: 5.371 ± 0.043	0.462ProCys: 0.462 ± 0.01	3.069ProAsp: 3.069 ± 0.026	3.604ProGlu: 3.604 ± 0.033	2.024ProPhe: 2.024 ± 0.022	3.84ProGly: 3.84 ± 0.028	1.345ProHis: 1.345 ± 0.017	2.75ProIle: 2.75 ± 0.027	3.037ProLys: 3.037 ± 0.041	4.611ProLeu: 4.611 ± 0.032	1.135ProMet: 1.135 ± 0.018	2.295ProAsn: 2.295 ± 0.025	5.381ProPro: 5.381 ± 0.076	2.52ProGln: 2.52 ± 0.034	3.391ProArg: 3.391 ± 0.033	6.005ProSer: 6.005 ± 0.047	4.138ProThr: 4.138 ± 0.037	3.477ProVal: 3.477 ± 0.033	0.698ProTrp: 0.698 ± 0.013	1.508ProTyr: 1.508 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	3.532GlnAla: 3.532 ± 0.034	0.438GlnCys: 0.438 ± 0.009	2.171GlnAsp: 2.171 ± 0.022	2.489GlnGlu: 2.489 ± 0.025	1.312GlnPhe: 1.312 ± 0.016	2.333GlnGly: 2.333 ± 0.025	1.128GlnHis: 1.128 ± 0.017	2.001GlnIle: 2.001 ± 0.021	2.117GlnLys: 2.117 ± 0.023	3.303GlnLeu: 3.303 ± 0.029	0.903GlnMet: 0.903 ± 0.015	1.633GlnAsn: 1.633 ± 0.02	2.485GlnPro: 2.485 ± 0.026	2.58GlnGln: 2.58 ± 0.052	2.559GlnArg: 2.559 ± 0.025	3.196GlnSer: 3.196 ± 0.031	2.366GlnThr: 2.366 ± 0.023	2.098GlnVal: 2.098 ± 0.02	0.548GlnTrp: 0.548 ± 0.01	1.206GlnTyr: 1.206 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	4.657ArgAla: 4.657 ± 0.031	0.643ArgCys: 0.643 ± 0.011	3.361ArgAsp: 3.361 ± 0.03	3.902ArgGlu: 3.902 ± 0.035	2.066ArgPhe: 2.066 ± 0.023	3.612ArgGly: 3.612 ± 0.033	1.501ArgHis: 1.501 ± 0.018	2.905ArgIle: 2.905 ± 0.025	3.761ArgLys: 3.761 ± 0.03	5.142ArgLeu: 5.142 ± 0.035	1.365ArgMet: 1.365 ± 0.015	2.34ArgAsn: 2.34 ± 0.023	3.503ArgPro: 3.503 ± 0.032	2.655ArgGln: 2.655 ± 0.024	4.933ArgArg: 4.933 ± 0.047	4.737ArgSer: 4.737 ± 0.046	3.347ArgThr: 3.347 ± 0.025	3.179ArgVal: 3.179 ± 0.024	0.854ArgTrp: 0.854 ± 0.013	1.567ArgTyr: 1.567 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	6.697SerAla: 6.697 ± 0.043	0.824SerCys: 0.824 ± 0.014	4.228SerAsp: 4.228 ± 0.032	4.237SerGlu: 4.237 ± 0.032	2.945SerPhe: 2.945 ± 0.022	5.508SerGly: 5.508 ± 0.038	1.93SerHis: 1.93 ± 0.02	4.078SerIle: 4.078 ± 0.028	4.154SerLys: 4.154 ± 0.034	6.946SerLeu: 6.946 ± 0.046	1.805SerMet: 1.805 ± 0.022	3.151SerAsn: 3.151 ± 0.024	5.628SerPro: 5.628 ± 0.053	3.277SerGln: 3.277 ± 0.032	5.001SerArg: 5.001 ± 0.043	8.939SerSer: 8.939 ± 0.08	5.789SerThr: 5.789 ± 0.046	4.418SerVal: 4.418 ± 0.03	1.06SerTrp: 1.06 ± 0.014	2.048SerTyr: 2.048 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	5.219ThrAla: 5.219 ± 0.033	0.698ThrCys: 0.698 ± 0.014	2.818ThrAsp: 2.818 ± 0.025	3.105ThrGlu: 3.105 ± 0.026	2.303ThrPhe: 2.303 ± 0.023	4.121ThrGly: 4.121 ± 0.036	1.259ThrHis: 1.259 ± 0.014	3.299ThrIle: 3.299 ± 0.027	2.992ThrLys: 2.992 ± 0.029	5.215ThrLeu: 5.215 ± 0.032	1.291ThrMet: 1.291 ± 0.017	2.285ThrAsn: 2.285 ± 0.022	4.443ThrPro: 4.443 ± 0.036	2.11ThrGln: 2.11 ± 0.021	3.166ThrArg: 3.166 ± 0.027	5.65ThrSer: 5.65 ± 0.043	4.472ThrThr: 4.472 ± 0.041	3.532ThrVal: 3.532 ± 0.027	0.833ThrTrp: 0.833 ± 0.012	1.564ThrTyr: 1.564 ± 0.017	0.0ThrXaa: 0.0 ± 0.0
Val	5.051ValAla: 5.051 ± 0.034	0.779ValCys: 0.779 ± 0.013	3.657ValAsp: 3.657 ± 0.031	3.995ValGlu: 3.995 ± 0.029	2.264ValPhe: 2.264 ± 0.024	3.965ValGly: 3.965 ± 0.032	1.336ValHis: 1.336 ± 0.017	2.8ValIle: 2.8 ± 0.026	3.127ValLys: 3.127 ± 0.028	5.265ValLeu: 5.265 ± 0.038	1.322ValMet: 1.322 ± 0.018	2.12ValAsn: 2.12 ± 0.022	3.523ValPro: 3.523 ± 0.027	2.367ValGln: 2.367 ± 0.023	3.309ValArg: 3.309 ± 0.026	4.438ValSer: 4.438 ± 0.03	3.307ValThr: 3.307 ± 0.022	4.112ValVal: 4.112 ± 0.03	0.85ValTrp: 0.85 ± 0.014	1.618ValTyr: 1.618 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	1.054TrpAla: 1.054 ± 0.014	0.194TrpCys: 0.194 ± 0.006	0.861TrpAsp: 0.861 ± 0.014	0.837TrpGlu: 0.837 ± 0.013	0.531TrpPhe: 0.531 ± 0.011	0.869TrpGly: 0.869 ± 0.016	0.344TrpHis: 0.344 ± 0.008	0.773TrpIle: 0.773 ± 0.013	0.853TrpLys: 0.853 ± 0.014	1.267TrpLeu: 1.267 ± 0.017	0.373TrpMet: 0.373 ± 0.009	0.642TrpAsn: 0.642 ± 0.013	0.603TrpPro: 0.603 ± 0.01	0.564TrpGln: 0.564 ± 0.01	0.957TrpArg: 0.957 ± 0.015	1.055TrpSer: 1.055 ± 0.015	0.935TrpThr: 0.935 ± 0.014	0.79TrpVal: 0.79 ± 0.012	0.266TrpTrp: 0.266 ± 0.007	0.395TrpTyr: 0.395 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.109TyrAla: 2.109 ± 0.021	0.396TyrCys: 0.396 ± 0.01	1.663TyrAsp: 1.663 ± 0.018	1.527TyrGlu: 1.527 ± 0.02	1.138TyrPhe: 1.138 ± 0.015	2.027TyrGly: 2.027 ± 0.024	0.713TyrHis: 0.713 ± 0.012	1.329TyrIle: 1.329 ± 0.019	1.186TyrLys: 1.186 ± 0.016	2.455TyrLeu: 2.455 ± 0.023	0.602TyrMet: 0.602 ± 0.012	1.133TyrAsn: 1.133 ± 0.015	1.429TyrPro: 1.429 ± 0.019	1.091TyrGln: 1.091 ± 0.015	1.496TyrArg: 1.496 ± 0.015	1.984TyrSer: 1.984 ± 0.02	1.619TyrThr: 1.619 ± 0.019	1.524TyrVal: 1.524 ± 0.018	0.424TyrTrp: 0.424 ± 0.009	0.86TyrTyr: 0.86 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 10819 proteins (5302218 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---