Amino acid dipepetide frequency for Thermosediminibacter oceani (strain ATCC BAA-1034 / DSM 16646 / JW/IW-1228P)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.62AlaAla: 7.62 ± 0.158
0.834AlaCys: 0.834 ± 0.041
3.5AlaAsp: 3.5 ± 0.068
5.517AlaGlu: 5.517 ± 0.108
3.355AlaPhe: 3.355 ± 0.081
6.875AlaGly: 6.875 ± 0.113
1.203AlaHis: 1.203 ± 0.035
5.409AlaIle: 5.409 ± 0.092
4.658AlaLys: 4.658 ± 0.075
8.715AlaLeu: 8.715 ± 0.121
2.185AlaMet: 2.185 ± 0.068
2.043AlaAsn: 2.043 ± 0.068
2.125AlaPro: 2.125 ± 0.075
1.995AlaGln: 1.995 ± 0.054
4.774AlaArg: 4.774 ± 0.103
3.62AlaSer: 3.62 ± 0.081
3.137AlaThr: 3.137 ± 0.069
7.294AlaVal: 7.294 ± 0.13
0.522AlaTrp: 0.522 ± 0.032
2.25AlaTyr: 2.25 ± 0.059
0.0AlaXaa: 0.0 ± 0.0
Cys
0.698CysAla: 0.698 ± 0.033
0.201CysCys: 0.201 ± 0.018
0.61CysAsp: 0.61 ± 0.032
0.637CysGlu: 0.637 ± 0.035
0.389CysPhe: 0.389 ± 0.025
1.192CysGly: 1.192 ± 0.048
0.224CysHis: 0.224 ± 0.019
0.682CysIle: 0.682 ± 0.036
0.514CysLys: 0.514 ± 0.03
0.825CysLeu: 0.825 ± 0.037
0.243CysMet: 0.243 ± 0.018
0.408CysAsn: 0.408 ± 0.027
0.684CysPro: 0.684 ± 0.041
0.238CysGln: 0.238 ± 0.02
0.699CysArg: 0.699 ± 0.036
0.618CysSer: 0.618 ± 0.03
0.438CysThr: 0.438 ± 0.029
0.624CysVal: 0.624 ± 0.03
0.083CysTrp: 0.083 ± 0.012
0.38CysTyr: 0.38 ± 0.026
0.0CysXaa: 0.0 ± 0.0
Asp
3.527AspAla: 3.527 ± 0.072
0.447AspCys: 0.447 ± 0.032
2.398AspAsp: 2.398 ± 0.077
4.266AspGlu: 4.266 ± 0.08
2.666AspPhe: 2.666 ± 0.067
3.58AspGly: 3.58 ± 0.089
0.748AspHis: 0.748 ± 0.032
4.769AspIle: 4.769 ± 0.091
3.075AspLys: 3.075 ± 0.075
5.337AspLeu: 5.337 ± 0.102
1.284AspMet: 1.284 ± 0.047
1.592AspAsn: 1.592 ± 0.053
2.341AspPro: 2.341 ± 0.059
0.952AspGln: 0.952 ± 0.039
2.842AspArg: 2.842 ± 0.069
2.276AspSer: 2.276 ± 0.057
2.191AspThr: 2.191 ± 0.06
4.079AspVal: 4.079 ± 0.084
0.427AspTrp: 0.427 ± 0.028
2.017AspTyr: 2.017 ± 0.053
0.0AspXaa: 0.0 ± 0.0
Glu
6.047GluAla: 6.047 ± 0.104
0.587GluCys: 0.587 ± 0.031
4.026GluAsp: 4.026 ± 0.099
7.18GluGlu: 7.18 ± 0.142
2.754GluPhe: 2.754 ± 0.074
5.014GluGly: 5.014 ± 0.094
1.019GluHis: 1.019 ± 0.04
6.825GluIle: 6.825 ± 0.117
7.6GluLys: 7.6 ± 0.117
7.314GluLeu: 7.314 ± 0.109
2.155GluMet: 2.155 ± 0.062
3.584GluAsn: 3.584 ± 0.081
2.153GluPro: 2.153 ± 0.063
1.974GluGln: 1.974 ± 0.057
4.523GluArg: 4.523 ± 0.088
3.005GluSer: 3.005 ± 0.077
2.952GluThr: 2.952 ± 0.074
5.712GluVal: 5.712 ± 0.098
0.497GluTrp: 0.497 ± 0.027
2.357GluTyr: 2.357 ± 0.064
0.0GluXaa: 0.0 ± 0.0
Phe
2.901PheAla: 2.901 ± 0.079
0.507PheCys: 0.507 ± 0.028
2.293PheAsp: 2.293 ± 0.057
2.815PheGlu: 2.815 ± 0.063
2.166PhePhe: 2.166 ± 0.076
3.22PheGly: 3.22 ± 0.072
0.638PheHis: 0.638 ± 0.036
3.312PheIle: 3.312 ± 0.074
2.479PheLys: 2.479 ± 0.063
4.349PheLeu: 4.349 ± 0.103
1.121PheMet: 1.121 ± 0.049
1.658PheAsn: 1.658 ± 0.052
1.724PhePro: 1.724 ± 0.053
0.997PheGln: 0.997 ± 0.043
1.932PheArg: 1.932 ± 0.058
2.799PheSer: 2.799 ± 0.072
2.214PheThr: 2.214 ± 0.056
2.718PheVal: 2.718 ± 0.059
0.37PheTrp: 0.37 ± 0.028
1.65PheTyr: 1.65 ± 0.056
0.0PheXaa: 0.0 ± 0.0
Gly
5.685GlyAla: 5.685 ± 0.115
1.043GlyCys: 1.043 ± 0.043
3.632GlyAsp: 3.632 ± 0.082
5.298GlyGlu: 5.298 ± 0.105
3.544GlyPhe: 3.544 ± 0.083
5.685GlyGly: 5.685 ± 0.117
1.233GlyHis: 1.233 ± 0.047
6.969GlyIle: 6.969 ± 0.112
5.329GlyLys: 5.329 ± 0.1
7.241GlyLeu: 7.241 ± 0.109
2.123GlyMet: 2.123 ± 0.057
2.586GlyAsn: 2.586 ± 0.067
2.299GlyPro: 2.299 ± 0.056
1.89GlyGln: 1.89 ± 0.06
4.521GlyArg: 4.521 ± 0.089
4.012GlySer: 4.012 ± 0.085
3.743GlyThr: 3.743 ± 0.089
6.01GlyVal: 6.01 ± 0.125
0.602GlyTrp: 0.602 ± 0.028
2.883GlyTyr: 2.883 ± 0.067
0.0GlyXaa: 0.0 ± 0.0
His
0.972HisAla: 0.972 ± 0.04
0.231HisCys: 0.231 ± 0.022
0.668HisAsp: 0.668 ± 0.033
0.91HisGlu: 0.91 ± 0.04
0.659HisPhe: 0.659 ± 0.032
1.273HisGly: 1.273 ± 0.049
0.369HisHis: 0.369 ± 0.022
1.299HisIle: 1.299 ± 0.042
0.823HisLys: 0.823 ± 0.032
1.557HisLeu: 1.557 ± 0.046
0.331HisMet: 0.331 ± 0.023
0.546HisAsn: 0.546 ± 0.028
0.95HisPro: 0.95 ± 0.042
0.428HisGln: 0.428 ± 0.025
0.968HisArg: 0.968 ± 0.045
0.828HisSer: 0.828 ± 0.036
0.737HisThr: 0.737 ± 0.037
1.019HisVal: 1.019 ± 0.038
0.157HisTrp: 0.157 ± 0.014
0.588HisTyr: 0.588 ± 0.027
0.0HisXaa: 0.0 ± 0.0
Ile
6.301IleAla: 6.301 ± 0.106
0.794IleCys: 0.794 ± 0.038
4.412IleAsp: 4.412 ± 0.079
5.89IleGlu: 5.89 ± 0.102
3.191IlePhe: 3.191 ± 0.07
5.357IleGly: 5.357 ± 0.104
1.135IleHis: 1.135 ± 0.043
6.159IleIle: 6.159 ± 0.119
6.181IleLys: 6.181 ± 0.107
7.744IleLeu: 7.744 ± 0.128
1.948IleMet: 1.948 ± 0.064
3.315IleAsn: 3.315 ± 0.083
3.85IlePro: 3.85 ± 0.089
1.739IleGln: 1.739 ± 0.053
3.927IleArg: 3.927 ± 0.083
4.694IleSer: 4.694 ± 0.091
4.23IleThr: 4.23 ± 0.081
5.39IleVal: 5.39 ± 0.102
0.47IleTrp: 0.47 ± 0.026
2.635IleTyr: 2.635 ± 0.07
0.0IleXaa: 0.0 ± 0.0
Lys
5.591LysAla: 5.591 ± 0.095
0.563LysCys: 0.563 ± 0.034
3.966LysAsp: 3.966 ± 0.087
6.159LysGlu: 6.159 ± 0.118
2.24LysPhe: 2.24 ± 0.056
4.986LysGly: 4.986 ± 0.088
0.986LysHis: 0.986 ± 0.04
5.905LysIle: 5.905 ± 0.097
6.452LysLys: 6.452 ± 0.116
6.134LysLeu: 6.134 ± 0.105
1.89LysMet: 1.89 ± 0.053
3.751LysAsn: 3.751 ± 0.081
2.713LysPro: 2.713 ± 0.065
1.709LysGln: 1.709 ± 0.046
3.709LysArg: 3.709 ± 0.081
3.482LysSer: 3.482 ± 0.075
3.367LysThr: 3.367 ± 0.07
5.395LysVal: 5.395 ± 0.097
0.461LysTrp: 0.461 ± 0.029
2.298LysTyr: 2.298 ± 0.06
0.0LysXaa: 0.0 ± 0.0
Leu
8.034LeuAla: 8.034 ± 0.132
1.013LeuCys: 1.013 ± 0.048
5.073LeuAsp: 5.073 ± 0.088
7.694LeuGlu: 7.694 ± 0.115
3.831LeuPhe: 3.831 ± 0.083
7.31LeuGly: 7.31 ± 0.124
1.292LeuHis: 1.292 ± 0.043
7.029LeuIle: 7.029 ± 0.128
8.464LeuLys: 8.464 ± 0.114
9.465LeuLeu: 9.465 ± 0.148
2.506LeuMet: 2.506 ± 0.069
3.976LeuAsn: 3.976 ± 0.079
4.07LeuPro: 4.07 ± 0.085
2.442LeuGln: 2.442 ± 0.072
5.033LeuArg: 5.033 ± 0.103
6.353LeuSer: 6.353 ± 0.116
4.67LeuThr: 4.67 ± 0.079
6.853LeuVal: 6.853 ± 0.112
0.717LeuTrp: 0.717 ± 0.038
2.95LeuTyr: 2.95 ± 0.073
0.0LeuXaa: 0.0 ± 0.0
Met
2.421MetAla: 2.421 ± 0.061
0.212MetCys: 0.212 ± 0.018
1.433MetAsp: 1.433 ± 0.051
2.1MetGlu: 2.1 ± 0.069
0.808MetPhe: 0.808 ± 0.041
2.2MetGly: 2.2 ± 0.058
0.365MetHis: 0.365 ± 0.026
1.821MetIle: 1.821 ± 0.055
1.993MetLys: 1.993 ± 0.059
2.592MetLeu: 2.592 ± 0.063
0.765MetMet: 0.765 ± 0.039
1.049MetAsn: 1.049 ± 0.039
1.175MetPro: 1.175 ± 0.046
0.602MetGln: 0.602 ± 0.03
1.418MetArg: 1.418 ± 0.043
1.219MetSer: 1.219 ± 0.045
1.393MetThr: 1.393 ± 0.043
2.028MetVal: 2.028 ± 0.058
0.155MetTrp: 0.155 ± 0.016
0.596MetTyr: 0.596 ± 0.032
0.0MetXaa: 0.0 ± 0.0
Asn
2.569AsnAla: 2.569 ± 0.065
0.45AsnCys: 0.45 ± 0.028
1.465AsnAsp: 1.465 ± 0.048
2.255AsnGlu: 2.255 ± 0.067
1.706AsnPhe: 1.706 ± 0.053
2.553AsnGly: 2.553 ± 0.065
0.527AsnHis: 0.527 ± 0.031
3.558AsnIle: 3.558 ± 0.082
2.274AsnLys: 2.274 ± 0.074
4.39AsnLeu: 4.39 ± 0.082
1.151AsnMet: 1.151 ± 0.045
1.43AsnAsn: 1.43 ± 0.055
2.346AsnPro: 2.346 ± 0.057
0.985AsnGln: 0.985 ± 0.044
2.142AsnArg: 2.142 ± 0.058
1.89AsnSer: 1.89 ± 0.061
1.821AsnThr: 1.821 ± 0.054
2.627AsnVal: 2.627 ± 0.063
0.337AsnTrp: 0.337 ± 0.025
1.474AsnTyr: 1.474 ± 0.052
0.0AsnXaa: 0.0 ± 0.0
Pro
2.991ProAla: 2.991 ± 0.075
0.398ProCys: 0.398 ± 0.024
2.417ProAsp: 2.417 ± 0.059
3.954ProGlu: 3.954 ± 0.086
1.813ProPhe: 1.813 ± 0.054
3.739ProGly: 3.739 ± 0.077
0.767ProHis: 0.767 ± 0.039
2.315ProIle: 2.315 ± 0.055
2.07ProLys: 2.07 ± 0.066
3.711ProLeu: 3.711 ± 0.069
0.903ProMet: 0.903 ± 0.036
1.214ProAsn: 1.214 ± 0.044
1.62ProPro: 1.62 ± 0.049
1.159ProGln: 1.159 ± 0.038
1.866ProArg: 1.866 ± 0.055
1.92ProSer: 1.92 ± 0.053
1.651ProThr: 1.651 ± 0.047
4.099ProVal: 4.099 ± 0.087
0.394ProTrp: 0.394 ± 0.027
1.448ProTyr: 1.448 ± 0.05
0.0ProXaa: 0.0 ± 0.0
Gln
2.02GlnAla: 2.02 ± 0.058
0.18GlnCys: 0.18 ± 0.018
1.247GlnAsp: 1.247 ± 0.043
2.178GlnGlu: 2.178 ± 0.067
0.761GlnPhe: 0.761 ± 0.035
1.653GlnGly: 1.653 ± 0.057
0.412GlnHis: 0.412 ± 0.026
1.86GlnIle: 1.86 ± 0.052
2.28GlnLys: 2.28 ± 0.058
2.37GlnLeu: 2.37 ± 0.067
0.74GlnMet: 0.74 ± 0.035
1.12GlnAsn: 1.12 ± 0.043
0.867GlnPro: 0.867 ± 0.036
0.881GlnGln: 0.881 ± 0.054
1.388GlnArg: 1.388 ± 0.054
1.021GlnSer: 1.021 ± 0.041
0.972GlnThr: 0.972 ± 0.042
1.993GlnVal: 1.993 ± 0.052
0.223GlnTrp: 0.223 ± 0.019
0.737GlnTyr: 0.737 ± 0.033
0.0GlnXaa: 0.0 ± 0.0
Arg
3.82ArgAla: 3.82 ± 0.075
0.601ArgCys: 0.601 ± 0.033
2.625ArgAsp: 2.625 ± 0.063
5.428ArgGlu: 5.428 ± 0.115
2.246ArgPhe: 2.246 ± 0.061
3.877ArgGly: 3.877 ± 0.082
0.826ArgHis: 0.826 ± 0.037
4.659ArgIle: 4.659 ± 0.091
3.996ArgLys: 3.996 ± 0.082
5.287ArgLeu: 5.287 ± 0.105
1.595ArgMet: 1.595 ± 0.046
1.989ArgAsn: 1.989 ± 0.054
1.974ArgPro: 1.974 ± 0.045
1.686ArgGln: 1.686 ± 0.058
3.193ArgArg: 3.193 ± 0.072
2.371ArgSer: 2.371 ± 0.072
2.318ArgThr: 2.318 ± 0.06
4.333ArgVal: 4.333 ± 0.105
0.522ArgTrp: 0.522 ± 0.031
1.761ArgTyr: 1.761 ± 0.049
0.0ArgXaa: 0.0 ± 0.0
Ser
3.811SerAla: 3.811 ± 0.09
0.599SerCys: 0.599 ± 0.029
2.5SerAsp: 2.5 ± 0.065
3.397SerGlu: 3.397 ± 0.068
2.407SerPhe: 2.407 ± 0.069
4.716SerGly: 4.716 ± 0.094
0.954SerHis: 0.954 ± 0.043
4.04SerIle: 4.04 ± 0.082
3.024SerLys: 3.024 ± 0.069
5.522SerLeu: 5.522 ± 0.121
1.38SerMet: 1.38 ± 0.046
1.593SerAsn: 1.593 ± 0.052
2.359SerPro: 2.359 ± 0.056
1.413SerGln: 1.413 ± 0.047
3.165SerArg: 3.165 ± 0.077
2.919SerSer: 2.919 ± 0.086
2.517SerThr: 2.517 ± 0.058
3.543SerVal: 3.543 ± 0.067
0.373SerTrp: 0.373 ± 0.025
1.653SerTyr: 1.653 ± 0.058
0.0SerXaa: 0.0 ± 0.0
Thr
3.983ThrAla: 3.983 ± 0.077
0.499ThrCys: 0.499 ± 0.03
2.089ThrAsp: 2.089 ± 0.058
2.738ThrGlu: 2.738 ± 0.071
2.036ThrPhe: 2.036 ± 0.057
4.655ThrGly: 4.655 ± 0.084
0.844ThrHis: 0.844 ± 0.037
3.308ThrIle: 3.308 ± 0.074
2.312ThrLys: 2.312 ± 0.066
4.67ThrLeu: 4.67 ± 0.096
1.076ThrMet: 1.076 ± 0.044
1.459ThrAsn: 1.459 ± 0.05
2.406ThrPro: 2.406 ± 0.065
1.034ThrGln: 1.034 ± 0.04
2.481ThrArg: 2.481 ± 0.061
2.412ThrSer: 2.412 ± 0.058
2.26ThrThr: 2.26 ± 0.061
4.216ThrVal: 4.216 ± 0.09
0.337ThrTrp: 0.337 ± 0.026
1.443ThrTyr: 1.443 ± 0.051
0.0ThrXaa: 0.0 ± 0.0
Val
5.966ValAla: 5.966 ± 0.114
0.761ValCys: 0.761 ± 0.033
4.242ValAsp: 4.242 ± 0.081
6.024ValGlu: 6.024 ± 0.12
3.301ValPhe: 3.301 ± 0.082
5.235ValGly: 5.235 ± 0.098
1.032ValHis: 1.032 ± 0.04
6.311ValIle: 6.311 ± 0.115
5.735ValLys: 5.735 ± 0.082
7.573ValLeu: 7.573 ± 0.122
2.0ValMet: 2.0 ± 0.059
2.964ValAsn: 2.964 ± 0.071
3.126ValPro: 3.126 ± 0.067
1.626ValGln: 1.626 ± 0.059
3.932ValArg: 3.932 ± 0.084
4.131ValSer: 4.131 ± 0.079
3.712ValThr: 3.712 ± 0.077
6.504ValVal: 6.504 ± 0.111
0.486ValTrp: 0.486 ± 0.028
2.412ValTyr: 2.412 ± 0.067
0.0ValXaa: 0.0 ± 0.0
Trp
0.541TrpAla: 0.541 ± 0.036
0.086TrpCys: 0.086 ± 0.011
0.42TrpAsp: 0.42 ± 0.025
0.561TrpGlu: 0.561 ± 0.029
0.343TrpPhe: 0.343 ± 0.024
0.61TrpGly: 0.61 ± 0.034
0.146TrpHis: 0.146 ± 0.017
0.529TrpIle: 0.529 ± 0.029
0.5TrpLys: 0.5 ± 0.026
0.682TrpLeu: 0.682 ± 0.039
0.235TrpMet: 0.235 ± 0.019
0.315TrpAsn: 0.315 ± 0.023
0.306TrpPro: 0.306 ± 0.021
0.292TrpGln: 0.292 ± 0.021
0.364TrpArg: 0.364 ± 0.022
0.37TrpSer: 0.37 ± 0.027
0.278TrpThr: 0.278 ± 0.022
0.511TrpVal: 0.511 ± 0.03
0.1TrpTrp: 0.1 ± 0.015
0.245TrpTyr: 0.245 ± 0.02
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.131TyrAla: 2.131 ± 0.062
0.383TyrCys: 0.383 ± 0.027
1.797TyrAsp: 1.797 ± 0.061
2.277TyrGlu: 2.277 ± 0.06
1.648TyrPhe: 1.648 ± 0.054
2.599TyrGly: 2.599 ± 0.065
0.591TyrHis: 0.591 ± 0.032
2.605TyrIle: 2.605 ± 0.071
1.995TyrLys: 1.995 ± 0.067
3.298TyrLeu: 3.298 ± 0.075
0.712TyrMet: 0.712 ± 0.033
1.36TyrAsn: 1.36 ± 0.053
1.36TyrPro: 1.36 ± 0.05
0.861TyrGln: 0.861 ± 0.039
2.233TyrArg: 2.233 ± 0.056
1.946TyrSer: 1.946 ± 0.064
1.655TyrThr: 1.655 ± 0.054
2.123TyrVal: 2.123 ± 0.065
0.201TyrTrp: 0.201 ± 0.018
1.314TyrTyr: 1.314 ± 0.051
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2151 proteins (637640 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski