Amino acid dipepetide frequency for Borna disease virus 1 (BoDV-1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.416AlaAla: 6.416 ± 1.33
0.583AlaCys: 0.583 ± 0.342
4.083AlaAsp: 4.083 ± 0.587
5.249AlaGlu: 5.249 ± 1.306
2.041AlaPhe: 2.041 ± 1.11
3.791AlaGly: 3.791 ± 0.834
0.292AlaHis: 0.292 ± 0.171
4.666AlaIle: 4.666 ± 1.525
3.5AlaLys: 3.5 ± 0.933
8.457AlaLeu: 8.457 ± 2.24
0.875AlaMet: 0.875 ± 0.35
1.167AlaAsn: 1.167 ± 0.46
3.791AlaPro: 3.791 ± 1.669
2.041AlaGln: 2.041 ± 0.574
4.958AlaArg: 4.958 ± 0.789
7.582AlaSer: 7.582 ± 1.717
3.5AlaThr: 3.5 ± 0.703
3.791AlaVal: 3.791 ± 0.43
1.458AlaTrp: 1.458 ± 1.128
2.041AlaTyr: 2.041 ± 0.318
0.0AlaXaa: 0.0 ± 0.0
Cys
0.583CysAla: 0.583 ± 0.342
1.167CysCys: 1.167 ± 0.446
1.167CysAsp: 1.167 ± 0.555
0.875CysGlu: 0.875 ± 0.541
0.583CysPhe: 0.583 ± 0.342
0.583CysGly: 0.583 ± 0.342
1.167CysHis: 1.167 ± 0.536
0.0CysIle: 0.0 ± 0.0
0.875CysLys: 0.875 ± 0.336
4.666CysLeu: 4.666 ± 1.449
0.583CysMet: 0.583 ± 0.527
1.167CysAsn: 1.167 ± 0.832
0.875CysPro: 0.875 ± 0.513
0.0CysGln: 0.0 ± 0.0
1.167CysArg: 1.167 ± 0.536
2.041CysSer: 2.041 ± 1.159
0.583CysThr: 0.583 ± 0.342
1.167CysVal: 1.167 ± 0.536
0.583CysTrp: 0.583 ± 0.342
0.583CysTyr: 0.583 ± 0.342
0.0CysXaa: 0.0 ± 0.0
Asp
3.208AspAla: 3.208 ± 1.134
1.458AspCys: 1.458 ± 0.583
1.167AspAsp: 1.167 ± 0.523
2.916AspGlu: 2.916 ± 1.479
2.625AspPhe: 2.625 ± 1.262
1.75AspGly: 1.75 ± 0.274
1.167AspHis: 1.167 ± 0.555
4.374AspIle: 4.374 ± 0.927
1.167AspLys: 1.167 ± 0.573
6.707AspLeu: 6.707 ± 0.785
2.041AspMet: 2.041 ± 0.57
0.875AspAsn: 0.875 ± 0.513
4.666AspPro: 4.666 ± 0.573
3.5AspGln: 3.5 ± 1.605
2.041AspArg: 2.041 ± 0.579
3.791AspSer: 3.791 ± 1.185
2.333AspThr: 2.333 ± 0.921
0.583AspVal: 0.583 ± 0.458
1.167AspTrp: 1.167 ± 0.361
2.333AspTyr: 2.333 ± 0.711
0.0AspXaa: 0.0 ± 0.0
Glu
3.791GluAla: 3.791 ± 0.968
1.167GluCys: 1.167 ± 0.446
3.5GluAsp: 3.5 ± 0.992
4.083GluGlu: 4.083 ± 0.726
2.916GluPhe: 2.916 ± 0.544
1.167GluGly: 1.167 ± 0.46
0.583GluHis: 0.583 ± 0.527
4.958GluIle: 4.958 ± 1.634
3.208GluLys: 3.208 ± 0.987
6.416GluLeu: 6.416 ± 0.943
0.875GluMet: 0.875 ± 0.338
2.041GluAsn: 2.041 ± 1.483
2.041GluPro: 2.041 ± 0.977
3.5GluGln: 3.5 ± 0.897
2.041GluArg: 2.041 ± 0.88
3.791GluSer: 3.791 ± 0.629
3.791GluThr: 3.791 ± 1.249
3.5GluVal: 3.5 ± 0.376
0.875GluTrp: 0.875 ± 0.575
1.458GluTyr: 1.458 ± 0.328
0.0GluXaa: 0.0 ± 0.0
Phe
1.75PheAla: 1.75 ± 0.804
0.292PheCys: 0.292 ± 0.171
1.458PheAsp: 1.458 ± 0.583
2.916PheGlu: 2.916 ± 0.479
1.75PhePhe: 1.75 ± 0.766
1.167PheGly: 1.167 ± 1.196
1.458PheHis: 1.458 ± 0.381
1.167PheIle: 1.167 ± 0.684
0.583PheLys: 0.583 ± 0.527
6.707PheLeu: 6.707 ± 2.487
1.167PheMet: 1.167 ± 0.773
2.333PheAsn: 2.333 ± 0.633
2.041PhePro: 2.041 ± 0.811
1.75PheGln: 1.75 ± 0.825
2.916PheArg: 2.916 ± 1.427
2.333PheSer: 2.333 ± 0.633
2.041PheThr: 2.041 ± 0.972
2.916PheVal: 2.916 ± 0.821
0.292PheTrp: 0.292 ± 0.171
1.75PheTyr: 1.75 ± 0.938
0.0PheXaa: 0.0 ± 0.0
Gly
4.374GlyAla: 4.374 ± 1.476
2.041GlyCys: 2.041 ± 0.928
2.333GlyAsp: 2.333 ± 0.894
4.666GlyGlu: 4.666 ± 2.293
1.75GlyPhe: 1.75 ± 0.686
3.208GlyGly: 3.208 ± 0.678
2.333GlyHis: 2.333 ± 0.422
1.75GlyIle: 1.75 ± 0.274
2.333GlyLys: 2.333 ± 0.702
5.249GlyLeu: 5.249 ± 0.895
0.583GlyMet: 0.583 ± 0.342
0.292GlyAsn: 0.292 ± 0.171
2.625GlyPro: 2.625 ± 1.469
2.041GlyGln: 2.041 ± 0.591
3.5GlyArg: 3.5 ± 1.044
4.666GlySer: 4.666 ± 1.637
4.083GlyThr: 4.083 ± 1.891
6.707GlyVal: 6.707 ± 0.898
1.167GlyTrp: 1.167 ± 0.973
2.333GlyTyr: 2.333 ± 0.43
0.0GlyXaa: 0.0 ± 0.0
His
2.625HisAla: 2.625 ± 0.854
0.875HisCys: 0.875 ± 0.59
0.875HisAsp: 0.875 ± 0.336
1.458HisGlu: 1.458 ± 1.078
0.583HisPhe: 0.583 ± 0.342
1.458HisGly: 1.458 ± 0.935
1.167HisHis: 1.167 ± 0.684
1.458HisIle: 1.458 ± 0.608
0.875HisLys: 0.875 ± 0.336
2.333HisLeu: 2.333 ± 1.093
0.292HisMet: 0.292 ± 0.171
0.583HisAsn: 0.583 ± 0.342
2.916HisPro: 2.916 ± 0.882
0.292HisGln: 0.292 ± 0.171
0.875HisArg: 0.875 ± 0.336
2.916HisSer: 2.916 ± 1.089
2.041HisThr: 2.041 ± 0.773
0.583HisVal: 0.583 ± 0.342
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.5IleAla: 3.5 ± 1.531
0.292IleCys: 0.292 ± 0.299
3.791IleAsp: 3.791 ± 1.292
2.625IleGlu: 2.625 ± 1.06
0.875IlePhe: 0.875 ± 0.418
5.249IleGly: 5.249 ± 1.505
0.292IleHis: 0.292 ± 0.171
4.374IleIle: 4.374 ± 1.432
5.541IleLys: 5.541 ± 2.441
4.374IleLeu: 4.374 ± 1.185
1.167IleMet: 1.167 ± 0.361
4.374IleAsn: 4.374 ± 0.836
3.208IlePro: 3.208 ± 1.324
2.333IleGln: 2.333 ± 0.54
6.707IleArg: 6.707 ± 0.83
4.958IleSer: 4.958 ± 1.477
2.041IleThr: 2.041 ± 0.843
2.625IleVal: 2.625 ± 0.822
0.0IleTrp: 0.0 ± 0.0
1.75IleTyr: 1.75 ± 0.686
0.0IleXaa: 0.0 ± 0.0
Lys
2.333LysAla: 2.333 ± 0.43
0.0LysCys: 0.0 ± 0.0
2.041LysAsp: 2.041 ± 1.194
4.374LysGlu: 4.374 ± 2.616
1.167LysPhe: 1.167 ± 1.053
1.458LysGly: 1.458 ± 0.608
0.875LysHis: 0.875 ± 0.931
2.041LysIle: 2.041 ± 1.116
2.916LysLys: 2.916 ± 1.096
7.291LysLeu: 7.291 ± 1.348
0.583LysMet: 0.583 ± 0.342
1.75LysAsn: 1.75 ± 0.727
0.875LysPro: 0.875 ± 0.336
0.875LysGln: 0.875 ± 0.513
2.333LysArg: 2.333 ± 0.591
3.5LysSer: 3.5 ± 2.052
4.666LysThr: 4.666 ± 1.159
2.916LysVal: 2.916 ± 0.983
0.292LysTrp: 0.292 ± 0.171
1.458LysTyr: 1.458 ± 0.588
0.0LysXaa: 0.0 ± 0.0
Leu
8.166LeuAla: 8.166 ± 0.856
2.916LeuCys: 2.916 ± 0.628
5.249LeuAsp: 5.249 ± 1.768
6.416LeuGlu: 6.416 ± 0.74
2.625LeuPhe: 2.625 ± 0.887
6.416LeuGly: 6.416 ± 1.008
1.75LeuHis: 1.75 ± 0.466
5.541LeuIle: 5.541 ± 0.43
5.541LeuLys: 5.541 ± 0.902
13.415LeuLeu: 13.415 ± 1.485
2.625LeuMet: 2.625 ± 0.869
4.958LeuAsn: 4.958 ± 2.296
8.166LeuPro: 8.166 ± 0.7
4.958LeuGln: 4.958 ± 0.841
4.666LeuArg: 4.666 ± 1.122
8.457LeuSer: 8.457 ± 0.699
7.291LeuThr: 7.291 ± 1.256
8.749LeuVal: 8.749 ± 1.382
0.875LeuTrp: 0.875 ± 0.513
4.958LeuTyr: 4.958 ± 1.264
0.0LeuXaa: 0.0 ± 0.0
Met
2.625MetAla: 2.625 ± 0.795
0.292MetCys: 0.292 ± 0.171
2.916MetAsp: 2.916 ± 0.761
2.041MetGlu: 2.041 ± 1.346
1.75MetPhe: 1.75 ± 1.122
0.583MetGly: 0.583 ± 0.342
0.0MetHis: 0.0 ± 0.0
2.041MetIle: 2.041 ± 1.346
1.458MetLys: 1.458 ± 1.207
1.458MetLeu: 1.458 ± 0.762
2.041MetMet: 2.041 ± 1.346
0.292MetAsn: 0.292 ± 0.488
1.167MetPro: 1.167 ± 0.414
1.167MetGln: 1.167 ± 0.46
1.167MetArg: 1.167 ± 0.361
1.75MetSer: 1.75 ± 0.766
1.75MetThr: 1.75 ± 0.274
0.875MetVal: 0.875 ± 0.513
0.292MetTrp: 0.292 ± 0.299
0.292MetTyr: 0.292 ± 0.299
0.0MetXaa: 0.0 ± 0.0
Asn
2.625AsnAla: 2.625 ± 0.541
0.292AsnCys: 0.292 ± 0.171
1.458AsnAsp: 1.458 ± 0.547
0.583AsnGlu: 0.583 ± 0.268
0.292AsnPhe: 0.292 ± 0.171
2.041AsnGly: 2.041 ± 1.159
1.167AsnHis: 1.167 ± 0.832
2.916AsnIle: 2.916 ± 1.37
0.875AsnLys: 0.875 ± 0.729
2.916AsnLeu: 2.916 ± 0.728
2.041AsnMet: 2.041 ± 0.369
0.583AsnAsn: 0.583 ± 0.268
2.916AsnPro: 2.916 ± 0.67
1.167AsnGln: 1.167 ± 0.573
1.75AsnArg: 1.75 ± 0.274
2.041AsnSer: 2.041 ± 1.192
1.167AsnThr: 1.167 ± 0.536
2.333AsnVal: 2.333 ± 1.033
0.292AsnTrp: 0.292 ± 0.299
0.583AsnTyr: 0.583 ± 0.268
0.0AsnXaa: 0.0 ± 0.0
Pro
4.374ProAla: 4.374 ± 0.406
1.458ProCys: 1.458 ± 0.855
2.625ProAsp: 2.625 ± 0.673
2.333ProGlu: 2.333 ± 0.921
2.625ProPhe: 2.625 ± 0.456
4.958ProGly: 4.958 ± 2.239
2.916ProHis: 2.916 ± 0.761
0.875ProIle: 0.875 ± 0.469
1.458ProLys: 1.458 ± 0.594
3.208ProLeu: 3.208 ± 1.246
1.167ProMet: 1.167 ± 1.316
0.875ProAsn: 0.875 ± 0.418
3.5ProPro: 3.5 ± 0.528
2.333ProGln: 2.333 ± 0.821
4.666ProArg: 4.666 ± 1.876
4.958ProSer: 4.958 ± 1.725
3.5ProThr: 3.5 ± 0.454
4.666ProVal: 4.666 ± 0.764
1.458ProTrp: 1.458 ± 0.381
2.333ProTyr: 2.333 ± 0.921
0.0ProXaa: 0.0 ± 0.0
Gln
1.167GlnAla: 1.167 ± 0.46
0.292GlnCys: 0.292 ± 0.299
1.458GlnAsp: 1.458 ± 0.381
0.875GlnGlu: 0.875 ± 0.541
1.75GlnPhe: 1.75 ± 0.588
2.333GlnGly: 2.333 ± 1.093
0.583GlnHis: 0.583 ± 0.342
2.625GlnIle: 2.625 ± 0.854
1.167GlnLys: 1.167 ± 0.684
6.124GlnLeu: 6.124 ± 1.265
1.458GlnMet: 1.458 ± 0.935
0.875GlnAsn: 0.875 ± 0.418
2.625GlnPro: 2.625 ± 0.741
0.875GlnGln: 0.875 ± 0.541
2.625GlnArg: 2.625 ± 1.157
2.916GlnSer: 2.916 ± 0.645
3.208GlnThr: 3.208 ± 1.099
2.041GlnVal: 2.041 ± 0.767
0.292GlnTrp: 0.292 ± 0.171
0.875GlnTyr: 0.875 ± 0.418
0.0GlnXaa: 0.0 ± 0.0
Arg
2.916ArgAla: 2.916 ± 1.046
1.167ArgCys: 1.167 ± 0.608
3.791ArgAsp: 3.791 ± 1.013
3.791ArgGlu: 3.791 ± 1.097
2.333ArgPhe: 2.333 ± 0.734
5.833ArgGly: 5.833 ± 1.114
1.167ArgHis: 1.167 ± 0.361
4.666ArgIle: 4.666 ± 1.583
1.75ArgLys: 1.75 ± 0.85
6.124ArgLeu: 6.124 ± 1.707
1.167ArgMet: 1.167 ± 0.361
1.167ArgAsn: 1.167 ± 1.002
4.666ArgPro: 4.666 ± 0.808
2.041ArgGln: 2.041 ± 0.591
6.124ArgArg: 6.124 ± 2.741
3.791ArgSer: 3.791 ± 0.774
2.041ArgThr: 2.041 ± 0.579
2.041ArgVal: 2.041 ± 0.787
1.167ArgTrp: 1.167 ± 0.46
2.333ArgTyr: 2.333 ± 1.054
0.0ArgXaa: 0.0 ± 0.0
Ser
8.457SerAla: 8.457 ± 2.103
2.916SerCys: 2.916 ± 1.165
4.666SerAsp: 4.666 ± 0.982
1.458SerGlu: 1.458 ± 0.608
5.541SerPhe: 5.541 ± 1.049
3.208SerGly: 3.208 ± 1.078
2.916SerHis: 2.916 ± 0.882
4.666SerIle: 4.666 ± 0.671
4.083SerLys: 4.083 ± 0.952
9.915SerLeu: 9.915 ± 0.877
2.041SerMet: 2.041 ± 1.577
1.458SerAsn: 1.458 ± 0.547
2.041SerPro: 2.041 ± 0.41
1.75SerGln: 1.75 ± 0.671
5.541SerArg: 5.541 ± 1.668
8.749SerSer: 8.749 ± 0.939
4.958SerThr: 4.958 ± 1.077
4.666SerVal: 4.666 ± 1.636
0.875SerTrp: 0.875 ± 0.513
3.5SerTyr: 3.5 ± 1.293
0.0SerXaa: 0.0 ± 0.0
Thr
4.083ThrAla: 4.083 ± 1.879
1.167ThrCys: 1.167 ± 0.46
2.916ThrAsp: 2.916 ± 0.645
2.625ThrGlu: 2.625 ± 0.601
2.041ThrPhe: 2.041 ± 0.843
4.083ThrGly: 4.083 ± 0.531
1.167ThrHis: 1.167 ± 0.684
6.416ThrIle: 6.416 ± 0.552
1.167ThrLys: 1.167 ± 0.684
6.999ThrLeu: 6.999 ± 0.643
3.5ThrMet: 3.5 ± 1.305
1.167ThrAsn: 1.167 ± 0.536
4.083ThrPro: 4.083 ± 1.182
2.625ThrGln: 2.625 ± 1.022
1.458ThrArg: 1.458 ± 0.643
4.374ThrSer: 4.374 ± 1.176
4.666ThrThr: 4.666 ± 1.404
4.666ThrVal: 4.666 ± 1.121
0.875ThrTrp: 0.875 ± 0.513
2.333ThrTyr: 2.333 ± 0.687
0.0ThrXaa: 0.0 ± 0.0
Val
4.374ValAla: 4.374 ± 0.928
0.583ValCys: 0.583 ± 0.342
3.791ValAsp: 3.791 ± 1.096
3.791ValGlu: 3.791 ± 1.351
2.916ValPhe: 2.916 ± 0.538
6.124ValGly: 6.124 ± 0.694
2.333ValHis: 2.333 ± 0.687
3.5ValIle: 3.5 ± 0.797
3.5ValLys: 3.5 ± 0.652
4.666ValLeu: 4.666 ± 1.449
1.167ValMet: 1.167 ± 0.46
2.333ValAsn: 2.333 ± 1.033
2.041ValPro: 2.041 ± 0.572
1.167ValGln: 1.167 ± 0.46
2.625ValArg: 2.625 ± 0.777
5.833ValSer: 5.833 ± 1.875
5.541ValThr: 5.541 ± 0.737
5.541ValVal: 5.541 ± 0.947
0.292ValTrp: 0.292 ± 0.299
1.458ValTyr: 1.458 ± 0.69
0.0ValXaa: 0.0 ± 0.0
Trp
0.583TrpAla: 0.583 ± 0.268
0.292TrpCys: 0.292 ± 0.171
0.583TrpAsp: 0.583 ± 0.642
0.875TrpGlu: 0.875 ± 0.336
0.583TrpPhe: 0.583 ± 0.598
0.583TrpGly: 0.583 ± 0.268
0.0TrpHis: 0.0 ± 0.0
0.875TrpIle: 0.875 ± 0.418
0.583TrpLys: 0.583 ± 0.342
1.75TrpLeu: 1.75 ± 0.804
0.0TrpMet: 0.0 ± 0.0
0.292TrpAsn: 0.292 ± 0.299
0.583TrpPro: 0.583 ± 0.458
0.875TrpGln: 0.875 ± 0.541
0.292TrpArg: 0.292 ± 0.171
1.75TrpSer: 1.75 ± 0.466
0.292TrpThr: 0.292 ± 0.171
1.75TrpVal: 1.75 ± 0.274
0.0TrpTrp: 0.0 ± 0.0
0.583TrpTyr: 0.583 ± 0.342
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.333TyrAla: 2.333 ± 0.54
1.167TyrCys: 1.167 ± 0.536
0.0TyrAsp: 0.0 ± 0.0
1.75TyrGlu: 1.75 ± 0.836
2.041TyrPhe: 2.041 ± 0.904
2.041TyrGly: 2.041 ± 0.318
0.875TyrHis: 0.875 ± 0.541
1.167TyrIle: 1.167 ± 0.536
1.167TyrLys: 1.167 ± 0.573
4.958TyrLeu: 4.958 ± 0.826
0.292TyrMet: 0.292 ± 0.488
1.458TyrAsn: 1.458 ± 0.583
1.75TyrPro: 1.75 ± 0.537
0.875TyrGln: 0.875 ± 0.336
2.625TyrArg: 2.625 ± 0.856
3.208TyrSer: 3.208 ± 1.372
2.916TyrThr: 2.916 ± 1.267
1.458TyrVal: 1.458 ± 0.69
0.875TyrTrp: 0.875 ± 0.59
1.167TyrTyr: 1.167 ± 0.46
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (3430 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski