Amino acid dipepetide frequency for Trebonia kvetii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	24.807AlaAla: 24.807 ± 0.154	1.278AlaCys: 1.278 ± 0.027	8.424AlaAsp: 8.424 ± 0.059	8.191AlaGlu: 8.191 ± 0.072	3.836AlaPhe: 3.836 ± 0.04	15.462AlaGly: 15.462 ± 0.101	2.436AlaHis: 2.436 ± 0.033	5.359AlaIle: 5.359 ± 0.045	2.821AlaLys: 2.821 ± 0.042	13.685AlaLeu: 13.685 ± 0.1	2.851AlaMet: 2.851 ± 0.035	2.469AlaAsn: 2.469 ± 0.032	6.601AlaPro: 6.601 ± 0.064	3.964AlaGln: 3.964 ± 0.04	10.309AlaArg: 10.309 ± 0.084	7.536AlaSer: 7.536 ± 0.063	7.311AlaThr: 7.311 ± 0.063	11.971AlaVal: 11.971 ± 0.081	2.115AlaTrp: 2.115 ± 0.034	2.631AlaTyr: 2.631 ± 0.033	0.0AlaXaa: 0.0 ± 0.0
Cys	1.13CysAla: 1.13 ± 0.026	0.132CysCys: 0.132 ± 0.008	0.503CysAsp: 0.503 ± 0.014	0.376CysGlu: 0.376 ± 0.011	0.233CysPhe: 0.233 ± 0.009	1.007CysGly: 1.007 ± 0.02	0.217CysHis: 0.217 ± 0.008	0.198CysIle: 0.198 ± 0.009	0.121CysLys: 0.121 ± 0.007	0.741CysLeu: 0.741 ± 0.015	0.13CysMet: 0.13 ± 0.008	0.158CysAsn: 0.158 ± 0.008	0.544CysPro: 0.544 ± 0.016	0.249CysGln: 0.249 ± 0.009	0.598CysArg: 0.598 ± 0.016	0.495CysSer: 0.495 ± 0.015	0.476CysThr: 0.476 ± 0.014	0.686CysVal: 0.686 ± 0.019	0.158CysTrp: 0.158 ± 0.009	0.239CysTyr: 0.239 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	7.176AspAla: 7.176 ± 0.057	0.414AspCys: 0.414 ± 0.012	3.269AspAsp: 3.269 ± 0.042	3.411AspGlu: 3.411 ± 0.042	1.546AspPhe: 1.546 ± 0.023	5.849AspGly: 5.849 ± 0.049	1.148AspHis: 1.148 ± 0.022	2.163AspIle: 2.163 ± 0.033	1.033AspLys: 1.033 ± 0.02	5.888AspLeu: 5.888 ± 0.044	0.936AspMet: 0.936 ± 0.018	1.003AspAsn: 1.003 ± 0.019	4.203AspPro: 4.203 ± 0.046	1.663AspGln: 1.663 ± 0.024	4.073AspArg: 4.073 ± 0.04	2.497AspSer: 2.497 ± 0.034	2.562AspThr: 2.562 ± 0.034	4.371AspVal: 4.371 ± 0.042	0.991AspTrp: 0.991 ± 0.021	1.244AspTyr: 1.244 ± 0.024	0.0AspXaa: 0.0 ± 0.0
Glu	6.435GluAla: 6.435 ± 0.063	0.354GluCys: 0.354 ± 0.011	2.242GluAsp: 2.242 ± 0.034	2.519GluGlu: 2.519 ± 0.034	1.579GluPhe: 1.579 ± 0.024	3.189GluGly: 3.189 ± 0.04	1.341GluHis: 1.341 ± 0.022	2.442GluIle: 2.442 ± 0.031	0.958GluLys: 0.958 ± 0.021	5.995GluLeu: 5.995 ± 0.052	0.948GluMet: 0.948 ± 0.02	0.899GluAsn: 0.899 ± 0.02	3.033GluPro: 3.033 ± 0.038	2.021GluGln: 2.021 ± 0.031	4.643GluArg: 4.643 ± 0.051	2.354GluSer: 2.354 ± 0.03	2.541GluThr: 2.541 ± 0.032	3.884GluVal: 3.884 ± 0.04	0.711GluTrp: 0.711 ± 0.018	1.069GluTyr: 1.069 ± 0.022	0.0GluXaa: 0.0 ± 0.0
Phe	4.128PheAla: 4.128 ± 0.041	0.319PheCys: 0.319 ± 0.013	1.821PheAsp: 1.821 ± 0.022	1.378PheGlu: 1.378 ± 0.023	0.955PhePhe: 0.955 ± 0.023	3.411PheGly: 3.411 ± 0.04	0.57PheHis: 0.57 ± 0.014	1.056PheIle: 1.056 ± 0.02	0.519PheLys: 0.519 ± 0.015	2.644PheLeu: 2.644 ± 0.034	0.449PheMet: 0.449 ± 0.013	0.671PheAsn: 0.671 ± 0.017	1.522PhePro: 1.522 ± 0.023	0.746PheGln: 0.746 ± 0.017	1.873PheArg: 1.873 ± 0.029	1.672PheSer: 1.672 ± 0.029	2.197PheThr: 2.197 ± 0.032	2.133PheVal: 2.133 ± 0.033	0.482PheTrp: 0.482 ± 0.014	0.678PheTyr: 0.678 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	11.033GlyAla: 11.033 ± 0.083	0.92GlyCys: 0.92 ± 0.02	4.897GlyAsp: 4.897 ± 0.049	4.568GlyGlu: 4.568 ± 0.043	3.095GlyPhe: 3.095 ± 0.037	9.009GlyGly: 9.009 ± 0.078	2.216GlyHis: 2.216 ± 0.027	4.153GlyIle: 4.153 ± 0.042	2.503GlyLys: 2.503 ± 0.038	9.425GlyLeu: 9.425 ± 0.073	2.164GlyMet: 2.164 ± 0.028	2.053GlyAsn: 2.053 ± 0.035	5.206GlyPro: 5.206 ± 0.063	3.547GlyGln: 3.547 ± 0.045	7.221GlyArg: 7.221 ± 0.059	5.83GlySer: 5.83 ± 0.062	6.392GlyThr: 6.392 ± 0.06	7.063GlyVal: 7.063 ± 0.056	1.842GlyTrp: 1.842 ± 0.027	2.735GlyTyr: 2.735 ± 0.037	0.0GlyXaa: 0.0 ± 0.0
His	2.657HisAla: 2.657 ± 0.032	0.203HisCys: 0.203 ± 0.009	1.246HisAsp: 1.246 ± 0.022	1.03HisGlu: 1.03 ± 0.021	0.598HisPhe: 0.598 ± 0.016	2.256HisGly: 2.256 ± 0.032	0.592HisHis: 0.592 ± 0.016	0.643HisIle: 0.643 ± 0.015	0.331HisLys: 0.331 ± 0.01	2.14HisLeu: 2.14 ± 0.03	0.351HisMet: 0.351 ± 0.011	0.369HisAsn: 0.369 ± 0.013	1.61HisPro: 1.61 ± 0.03	0.639HisGln: 0.639 ± 0.016	1.619HisArg: 1.619 ± 0.03	0.96HisSer: 0.96 ± 0.02	0.972HisThr: 0.972 ± 0.018	1.644HisVal: 1.644 ± 0.027	0.375HisTrp: 0.375 ± 0.013	0.512HisTyr: 0.512 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	6.301IleAla: 6.301 ± 0.056	0.358IleCys: 0.358 ± 0.012	2.49IleAsp: 2.49 ± 0.034	2.233IleGlu: 2.233 ± 0.035	1.046IlePhe: 1.046 ± 0.021	4.276IleGly: 4.276 ± 0.04	0.619IleHis: 0.619 ± 0.018	1.518IleIle: 1.518 ± 0.028	0.796IleLys: 0.796 ± 0.019	2.983IleLeu: 2.983 ± 0.037	0.624IleMet: 0.624 ± 0.015	0.875IleAsn: 0.875 ± 0.019	2.239IlePro: 2.239 ± 0.029	0.866IleGln: 0.866 ± 0.02	2.636IleArg: 2.636 ± 0.034	2.239IleSer: 2.239 ± 0.03	2.7IleThr: 2.7 ± 0.036	3.42IleVal: 3.42 ± 0.042	0.514IleTrp: 0.514 ± 0.014	0.783IleTyr: 0.783 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	2.581LysAla: 2.581 ± 0.032	0.121LysCys: 0.121 ± 0.006	0.98LysAsp: 0.98 ± 0.022	0.862LysGlu: 0.862 ± 0.019	0.522LysPhe: 0.522 ± 0.015	1.429LysGly: 1.429 ± 0.026	0.416LysHis: 0.416 ± 0.013	0.928LysIle: 0.928 ± 0.019	0.532LysLys: 0.532 ± 0.017	1.984LysLeu: 1.984 ± 0.03	0.383LysMet: 0.383 ± 0.014	0.484LysAsn: 0.484 ± 0.015	1.311LysPro: 1.311 ± 0.022	0.657LysGln: 0.657 ± 0.019	1.356LysArg: 1.356 ± 0.025	1.118LysSer: 1.118 ± 0.025	1.297LysThr: 1.297 ± 0.023	1.61LysVal: 1.61 ± 0.025	0.273LysTrp: 0.273 ± 0.012	0.474LysTyr: 0.474 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	16.428LeuAla: 16.428 ± 0.101	0.786LeuCys: 0.786 ± 0.018	6.009LeuAsp: 6.009 ± 0.056	4.086LeuGlu: 4.086 ± 0.049	2.651LeuPhe: 2.651 ± 0.039	9.11LeuGly: 9.11 ± 0.069	1.978LeuHis: 1.978 ± 0.026	4.186LeuIle: 4.186 ± 0.044	1.643LeuLys: 1.643 ± 0.026	10.325LeuLeu: 10.325 ± 0.08	1.541LeuMet: 1.541 ± 0.024	1.902LeuAsn: 1.902 ± 0.027	6.259LeuPro: 6.259 ± 0.057	2.112LeuGln: 2.112 ± 0.031	8.102LeuArg: 8.102 ± 0.066	5.82LeuSer: 5.82 ± 0.051	6.635LeuThr: 6.635 ± 0.054	7.782LeuVal: 7.782 ± 0.066	1.227LeuTrp: 1.227 ± 0.023	1.772LeuTyr: 1.772 ± 0.026	0.0LeuXaa: 0.0 ± 0.0
Met	2.541MetAla: 2.541 ± 0.033	0.139MetCys: 0.139 ± 0.007	0.843MetAsp: 0.843 ± 0.021	0.717MetGlu: 0.717 ± 0.019	0.563MetPhe: 0.563 ± 0.015	1.22MetGly: 1.22 ± 0.024	0.369MetHis: 0.369 ± 0.012	0.879MetIle: 0.879 ± 0.019	0.405MetLys: 0.405 ± 0.013	2.015MetLeu: 2.015 ± 0.03	0.358MetMet: 0.358 ± 0.013	0.464MetAsn: 0.464 ± 0.013	1.275MetPro: 1.275 ± 0.022	0.487MetGln: 0.487 ± 0.012	1.494MetArg: 1.494 ± 0.026	1.363MetSer: 1.363 ± 0.026	1.726MetThr: 1.726 ± 0.028	1.261MetVal: 1.261 ± 0.021	0.214MetTrp: 0.214 ± 0.01	0.334MetTyr: 0.334 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	2.523AsnAla: 2.523 ± 0.035	0.199AsnCys: 0.199 ± 0.01	0.963AsnAsp: 0.963 ± 0.02	0.872AsnGlu: 0.872 ± 0.019	0.584AsnPhe: 0.584 ± 0.016	2.247AsnGly: 2.247 ± 0.037	0.396AsnHis: 0.396 ± 0.013	0.737AsnIle: 0.737 ± 0.017	0.371AsnLys: 0.371 ± 0.012	1.906AsnLeu: 1.906 ± 0.03	0.358AsnMet: 0.358 ± 0.012	0.485AsnAsn: 0.485 ± 0.017	1.607AsnPro: 1.607 ± 0.031	0.607AsnGln: 0.607 ± 0.016	1.254AsnArg: 1.254 ± 0.022	1.073AsnSer: 1.073 ± 0.022	1.165AsnThr: 1.165 ± 0.022	1.579AsnVal: 1.579 ± 0.026	0.384AsnTrp: 0.384 ± 0.013	0.517AsnTyr: 0.517 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	9.679ProAla: 9.679 ± 0.087	0.349ProCys: 0.349 ± 0.011	4.237ProAsp: 4.237 ± 0.042	3.37ProGlu: 3.37 ± 0.04	1.651ProPhe: 1.651 ± 0.023	7.357ProGly: 7.357 ± 0.075	1.173ProHis: 1.173 ± 0.024	1.496ProIle: 1.496 ± 0.025	0.995ProLys: 0.995 ± 0.021	5.09ProLeu: 5.09 ± 0.045	1.085ProMet: 1.085 ± 0.023	1.102ProAsn: 1.102 ± 0.023	3.71ProPro: 3.71 ± 0.052	1.673ProGln: 1.673 ± 0.028	3.837ProArg: 3.837 ± 0.041	3.397ProSer: 3.397 ± 0.039	2.604ProThr: 2.604 ± 0.035	5.501ProVal: 5.501 ± 0.05	0.953ProTrp: 0.953 ± 0.02	1.26ProTyr: 1.26 ± 0.025	0.0ProXaa: 0.0 ± 0.0
Gln	4.63GlnAla: 4.63 ± 0.049	0.205GlnCys: 0.205 ± 0.008	1.355GlnAsp: 1.355 ± 0.02	1.253GlnGlu: 1.253 ± 0.023	0.874GlnPhe: 0.874 ± 0.019	2.167GlnGly: 2.167 ± 0.038	0.663GlnHis: 0.663 ± 0.016	1.19GlnIle: 1.19 ± 0.023	0.477GlnLys: 0.477 ± 0.014	3.267GlnLeu: 3.267 ± 0.038	0.546GlnMet: 0.546 ± 0.014	0.573GlnAsn: 0.573 ± 0.015	2.068GlnPro: 2.068 ± 0.034	1.31GlnGln: 1.31 ± 0.03	2.505GlnArg: 2.505 ± 0.033	1.42GlnSer: 1.42 ± 0.023	1.409GlnThr: 1.409 ± 0.022	2.811GlnVal: 2.811 ± 0.035	0.536GlnTrp: 0.536 ± 0.015	0.647GlnTyr: 0.647 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	9.534ArgAla: 9.534 ± 0.074	0.627ArgCys: 0.627 ± 0.017	4.266ArgAsp: 4.266 ± 0.043	4.042ArgGlu: 4.042 ± 0.047	2.313ArgPhe: 2.313 ± 0.03	5.571ArgGly: 5.571 ± 0.055	1.921ArgHis: 1.921 ± 0.028	3.023ArgIle: 3.023 ± 0.034	1.509ArgLys: 1.509 ± 0.026	8.324ArgLeu: 8.324 ± 0.068	1.687ArgMet: 1.687 ± 0.026	1.38ArgAsn: 1.38 ± 0.021	4.54ArgPro: 4.54 ± 0.051	2.664ArgGln: 2.664 ± 0.04	7.107ArgArg: 7.107 ± 0.072	3.974ArgSer: 3.974 ± 0.045	3.981ArgThr: 3.981 ± 0.045	5.637ArgVal: 5.637 ± 0.053	1.394ArgTrp: 1.394 ± 0.023	1.938ArgTyr: 1.938 ± 0.027	0.0ArgXaa: 0.0 ± 0.0
Ser	7.975SerAla: 7.975 ± 0.062	0.522SerCys: 0.522 ± 0.017	2.735SerAsp: 2.735 ± 0.038	2.207SerGlu: 2.207 ± 0.032	1.782SerPhe: 1.782 ± 0.027	6.482SerGly: 6.482 ± 0.068	1.099SerHis: 1.099 ± 0.021	1.845SerIle: 1.845 ± 0.027	1.028SerLys: 1.028 ± 0.023	5.187SerLeu: 5.187 ± 0.047	1.176SerMet: 1.176 ± 0.022	1.052SerAsn: 1.052 ± 0.026	3.584SerPro: 3.584 ± 0.041	1.648SerGln: 1.648 ± 0.03	3.936SerArg: 3.936 ± 0.043	3.566SerSer: 3.566 ± 0.049	3.045SerThr: 3.045 ± 0.04	4.522SerVal: 4.522 ± 0.038	1.019SerTrp: 1.019 ± 0.022	1.43SerTyr: 1.43 ± 0.027	0.0SerXaa: 0.0 ± 0.0
Thr	8.763ThrAla: 8.763 ± 0.064	0.45ThrCys: 0.45 ± 0.013	3.047ThrAsp: 3.047 ± 0.037	2.806ThrGlu: 2.806 ± 0.032	1.702ThrPhe: 1.702 ± 0.028	6.662ThrGly: 6.662 ± 0.055	1.037ThrHis: 1.037 ± 0.018	2.314ThrIle: 2.314 ± 0.032	1.001ThrLys: 1.001 ± 0.019	5.524ThrLeu: 5.524 ± 0.046	1.068ThrMet: 1.068 ± 0.024	1.036ThrAsn: 1.036 ± 0.021	3.769ThrPro: 3.769 ± 0.044	1.517ThrGln: 1.517 ± 0.026	3.684ThrArg: 3.684 ± 0.038	3.448ThrSer: 3.448 ± 0.045	3.365ThrThr: 3.365 ± 0.045	5.603ThrVal: 5.603 ± 0.059	0.967ThrTrp: 0.967 ± 0.022	1.188ThrTyr: 1.188 ± 0.024	0.0ThrXaa: 0.0 ± 0.0
Val	11.203ValAla: 11.203 ± 0.08	0.662ValCys: 0.662 ± 0.016	3.955ValAsp: 3.955 ± 0.045	3.51ValGlu: 3.51 ± 0.036	2.447ValPhe: 2.447 ± 0.031	5.873ValGly: 5.873 ± 0.052	1.619ValHis: 1.619 ± 0.027	4.089ValIle: 4.089 ± 0.041	1.586ValLys: 1.586 ± 0.028	8.776ValLeu: 8.776 ± 0.067	1.405ValMet: 1.405 ± 0.025	1.908ValAsn: 1.908 ± 0.031	5.176ValPro: 5.176 ± 0.051	1.984ValGln: 1.984 ± 0.029	5.971ValArg: 5.971 ± 0.051	4.977ValSer: 4.977 ± 0.054	6.328ValThr: 6.328 ± 0.051	6.732ValVal: 6.732 ± 0.064	1.032ValTrp: 1.032 ± 0.02	1.609ValTyr: 1.609 ± 0.023	0.0ValXaa: 0.0 ± 0.0
Trp	1.754TrpAla: 1.754 ± 0.028	0.144TrpCys: 0.144 ± 0.008	0.809TrpAsp: 0.809 ± 0.019	0.665TrpGlu: 0.665 ± 0.016	0.526TrpPhe: 0.526 ± 0.016	1.099TrpGly: 1.099 ± 0.023	0.447TrpHis: 0.447 ± 0.015	0.64TrpIle: 0.64 ± 0.016	0.299TrpLys: 0.299 ± 0.012	1.958TrpLeu: 1.958 ± 0.031	0.319TrpMet: 0.319 ± 0.01	0.462TrpAsn: 0.462 ± 0.017	0.929TrpPro: 0.929 ± 0.019	0.685TrpGln: 0.685 ± 0.015	1.421TrpArg: 1.421 ± 0.026	0.971TrpSer: 0.971 ± 0.021	1.051TrpThr: 1.051 ± 0.022	1.019TrpVal: 1.019 ± 0.02	0.348TrpTrp: 0.348 ± 0.012	0.379TrpTyr: 0.379 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.777TyrAla: 2.777 ± 0.036	0.208TyrCys: 0.208 ± 0.01	1.347TyrAsp: 1.347 ± 0.024	1.061TyrGlu: 1.061 ± 0.021	0.719TyrPhe: 0.719 ± 0.016	2.194TyrGly: 2.194 ± 0.037	0.492TyrHis: 0.492 ± 0.014	0.656TyrIle: 0.656 ± 0.016	0.391TyrLys: 0.391 ± 0.013	2.496TyrLeu: 2.496 ± 0.033	0.287TyrMet: 0.287 ± 0.009	0.481TyrAsn: 0.481 ± 0.015	1.333TyrPro: 1.333 ± 0.026	0.869TyrGln: 0.869 ± 0.018	1.796TyrArg: 1.796 ± 0.028	1.129TyrSer: 1.129 ± 0.022	1.195TyrThr: 1.195 ± 0.025	1.614TyrVal: 1.614 ± 0.025	0.391TyrTrp: 0.391 ± 0.011	0.578TyrTyr: 0.578 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8100 proteins (2589830 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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