Amino acid dipepetide frequency for Paraburkholderia panacisoli

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.472AlaAla: 17.472 ± 0.132	1.31AlaCys: 1.31 ± 0.022	6.491AlaAsp: 6.491 ± 0.048	5.988AlaGlu: 5.988 ± 0.053	4.343AlaPhe: 4.343 ± 0.039	10.214AlaGly: 10.214 ± 0.058	2.859AlaHis: 2.859 ± 0.034	5.886AlaIle: 5.886 ± 0.049	3.643AlaLys: 3.643 ± 0.044	14.048AlaLeu: 14.048 ± 0.082	3.26AlaMet: 3.26 ± 0.035	3.316AlaAsn: 3.316 ± 0.035	5.756AlaPro: 5.756 ± 0.06	5.269AlaGln: 5.269 ± 0.056	8.769AlaArg: 8.769 ± 0.074	7.557AlaSer: 7.557 ± 0.061	6.399AlaThr: 6.399 ± 0.047	8.867AlaVal: 8.867 ± 0.069	1.634AlaTrp: 1.634 ± 0.022	2.712AlaTyr: 2.712 ± 0.032	0.0AlaXaa: 0.0 ± 0.0
Cys	1.263CysAla: 1.263 ± 0.025	0.143CysCys: 0.143 ± 0.008	0.56CysAsp: 0.56 ± 0.014	0.533CysGlu: 0.533 ± 0.013	0.353CysPhe: 0.353 ± 0.011	1.042CysGly: 1.042 ± 0.021	0.247CysHis: 0.247 ± 0.011	0.422CysIle: 0.422 ± 0.012	0.242CysLys: 0.242 ± 0.009	0.818CysLeu: 0.818 ± 0.017	0.222CysMet: 0.222 ± 0.01	0.257CysAsn: 0.257 ± 0.01	0.446CysPro: 0.446 ± 0.014	0.231CysGln: 0.231 ± 0.008	0.648CysArg: 0.648 ± 0.015	0.552CysSer: 0.552 ± 0.014	0.508CysThr: 0.508 ± 0.015	0.832CysVal: 0.832 ± 0.017	0.131CysTrp: 0.131 ± 0.007	0.241CysTyr: 0.241 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	7.395AspAla: 7.395 ± 0.056	0.453AspCys: 0.453 ± 0.012	3.046AspAsp: 3.046 ± 0.038	3.375AspGlu: 3.375 ± 0.04	1.963AspPhe: 1.963 ± 0.027	4.499AspGly: 4.499 ± 0.044	1.183AspHis: 1.183 ± 0.022	2.505AspIle: 2.505 ± 0.026	1.485AspLys: 1.485 ± 0.025	5.132AspLeu: 5.132 ± 0.042	1.126AspMet: 1.126 ± 0.021	1.301AspAsn: 1.301 ± 0.024	2.866AspPro: 2.866 ± 0.034	1.598AspGln: 1.598 ± 0.024	3.371AspArg: 3.371 ± 0.038	2.597AspSer: 2.597 ± 0.032	2.763AspThr: 2.763 ± 0.032	4.312AspVal: 4.312 ± 0.041	0.899AspTrp: 0.899 ± 0.019	1.46AspTyr: 1.46 ± 0.021	0.0AspXaa: 0.0 ± 0.0
Glu	6.365GluAla: 6.365 ± 0.055	0.417GluCys: 0.417 ± 0.013	2.081GluAsp: 2.081 ± 0.027	2.449GluGlu: 2.449 ± 0.035	1.831GluPhe: 1.831 ± 0.026	3.325GluGly: 3.325 ± 0.039	1.473GluHis: 1.473 ± 0.025	2.766GluIle: 2.766 ± 0.039	1.795GluLys: 1.795 ± 0.028	5.548GluLeu: 5.548 ± 0.056	1.236GluMet: 1.236 ± 0.021	1.39GluAsn: 1.39 ± 0.024	2.492GluPro: 2.492 ± 0.027	2.43GluGln: 2.43 ± 0.03	4.849GluArg: 4.849 ± 0.045	2.747GluSer: 2.747 ± 0.036	2.815GluThr: 2.815 ± 0.035	3.555GluVal: 3.555 ± 0.043	0.757GluTrp: 0.757 ± 0.016	1.136GluTyr: 1.136 ± 0.022	0.0GluXaa: 0.0 ± 0.0
Phe	4.731PheAla: 4.731 ± 0.048	0.437PheCys: 0.437 ± 0.014	2.749PheAsp: 2.749 ± 0.03	2.065PheGlu: 2.065 ± 0.03	1.521PhePhe: 1.521 ± 0.028	3.731PheGly: 3.731 ± 0.04	0.77PheHis: 0.77 ± 0.015	1.685PheIle: 1.685 ± 0.028	1.047PheLys: 1.047 ± 0.02	3.055PheLeu: 3.055 ± 0.04	0.791PheMet: 0.791 ± 0.019	1.2PheAsn: 1.2 ± 0.021	1.601PhePro: 1.601 ± 0.024	0.99PheGln: 0.99 ± 0.019	2.069PheArg: 2.069 ± 0.028	2.383PheSer: 2.383 ± 0.03	1.995PheThr: 1.995 ± 0.026	3.116PheVal: 3.116 ± 0.036	0.519PheTrp: 0.519 ± 0.015	0.979PheTyr: 0.979 ± 0.019	0.0PheXaa: 0.0 ± 0.0
Gly	9.288GlyAla: 9.288 ± 0.076	0.893GlyCys: 0.893 ± 0.018	3.79GlyAsp: 3.79 ± 0.036	4.201GlyGlu: 4.201 ± 0.04	3.429GlyPhe: 3.429 ± 0.038	6.726GlyGly: 6.726 ± 0.071	1.962GlyHis: 1.962 ± 0.032	4.37GlyIle: 4.37 ± 0.041	3.161GlyLys: 3.161 ± 0.035	7.987GlyLeu: 7.987 ± 0.066	2.201GlyMet: 2.201 ± 0.027	2.364GlyAsn: 2.364 ± 0.033	2.955GlyPro: 2.955 ± 0.038	2.736GlyGln: 2.736 ± 0.034	5.214GlyArg: 5.214 ± 0.048	4.736GlySer: 4.736 ± 0.045	4.576GlyThr: 4.576 ± 0.051	6.67GlyVal: 6.67 ± 0.054	1.362GlyTrp: 1.362 ± 0.024	2.42GlyTyr: 2.42 ± 0.03	0.0GlyXaa: 0.0 ± 0.0
His	3.108HisAla: 3.108 ± 0.038	0.279HisCys: 0.279 ± 0.011	1.357HisAsp: 1.357 ± 0.023	1.223HisGlu: 1.223 ± 0.023	0.97HisPhe: 0.97 ± 0.019	2.203HisGly: 2.203 ± 0.032	0.653HisHis: 0.653 ± 0.016	0.964HisIle: 0.964 ± 0.018	0.551HisLys: 0.551 ± 0.014	2.23HisLeu: 2.23 ± 0.03	0.536HisMet: 0.536 ± 0.014	0.563HisAsn: 0.563 ± 0.013	1.452HisPro: 1.452 ± 0.022	0.685HisGln: 0.685 ± 0.016	1.633HisArg: 1.633 ± 0.023	1.19HisSer: 1.19 ± 0.023	1.128HisThr: 1.128 ± 0.017	1.773HisVal: 1.773 ± 0.027	0.415HisTrp: 0.415 ± 0.011	0.679HisTyr: 0.679 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	6.991IleAla: 6.991 ± 0.052	0.493IleCys: 0.493 ± 0.013	3.432IleAsp: 3.432 ± 0.039	3.27IleGlu: 3.27 ± 0.039	1.527IlePhe: 1.527 ± 0.027	4.813IleGly: 4.813 ± 0.048	0.947IleHis: 0.947 ± 0.018	1.675IleIle: 1.675 ± 0.027	1.384IleLys: 1.384 ± 0.023	3.504IleLeu: 3.504 ± 0.041	0.788IleMet: 0.788 ± 0.019	1.445IleAsn: 1.445 ± 0.026	2.16IlePro: 2.16 ± 0.031	1.285IleGln: 1.285 ± 0.024	2.886IleArg: 2.886 ± 0.033	2.645IleSer: 2.645 ± 0.031	2.461IleThr: 2.461 ± 0.032	4.434IleVal: 4.434 ± 0.042	0.52IleTrp: 0.52 ± 0.014	1.076IleTyr: 1.076 ± 0.019	0.0IleXaa: 0.0 ± 0.0
Lys	3.588LysAla: 3.588 ± 0.042	0.195LysCys: 0.195 ± 0.008	1.468LysAsp: 1.468 ± 0.025	1.46LysGlu: 1.46 ± 0.026	0.9LysPhe: 0.9 ± 0.019	2.198LysGly: 2.198 ± 0.032	0.71LysHis: 0.71 ± 0.017	1.549LysIle: 1.549 ± 0.025	1.221LysLys: 1.221 ± 0.025	3.377LysLeu: 3.377 ± 0.037	0.794LysMet: 0.794 ± 0.017	0.88LysAsn: 0.88 ± 0.018	1.921LysPro: 1.921 ± 0.029	1.29LysGln: 1.29 ± 0.023	2.386LysArg: 2.386 ± 0.032	1.766LysSer: 1.766 ± 0.024	1.885LysThr: 1.885 ± 0.033	2.353LysVal: 2.353 ± 0.034	0.401LysTrp: 0.401 ± 0.012	0.694LysTyr: 0.694 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	13.735LeuAla: 13.735 ± 0.081	1.06LeuCys: 1.06 ± 0.021	5.882LeuAsp: 5.882 ± 0.046	5.059LeuGlu: 5.059 ± 0.049	3.661LeuPhe: 3.661 ± 0.044	8.065LeuGly: 8.065 ± 0.066	2.343LeuHis: 2.343 ± 0.033	4.8LeuIle: 4.8 ± 0.044	3.361LeuLys: 3.361 ± 0.035	10.134LeuLeu: 10.134 ± 0.094	2.304LeuMet: 2.304 ± 0.03	2.891LeuAsn: 2.891 ± 0.034	5.596LeuPro: 5.596 ± 0.043	3.42LeuGln: 3.42 ± 0.034	7.128LeuArg: 7.128 ± 0.054	6.407LeuSer: 6.407 ± 0.056	5.662LeuThr: 5.662 ± 0.049	7.384LeuVal: 7.384 ± 0.063	1.149LeuTrp: 1.149 ± 0.023	2.206LeuTyr: 2.206 ± 0.03	0.0LeuXaa: 0.0 ± 0.0
Met	2.525MetAla: 2.525 ± 0.032	0.197MetCys: 0.197 ± 0.008	1.0MetAsp: 1.0 ± 0.019	0.932MetGlu: 0.932 ± 0.02	0.786MetPhe: 0.786 ± 0.02	1.579MetGly: 1.579 ± 0.027	0.568MetHis: 0.568 ± 0.015	1.143MetIle: 1.143 ± 0.021	1.071MetLys: 1.071 ± 0.02	2.723MetLeu: 2.723 ± 0.031	0.591MetMet: 0.591 ± 0.017	0.946MetAsn: 0.946 ± 0.016	1.444MetPro: 1.444 ± 0.024	0.991MetGln: 0.991 ± 0.018	1.813MetArg: 1.813 ± 0.027	1.778MetSer: 1.778 ± 0.025	1.672MetThr: 1.672 ± 0.027	1.515MetVal: 1.515 ± 0.023	0.219MetTrp: 0.219 ± 0.008	0.396MetTyr: 0.396 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.603AsnAla: 3.603 ± 0.038	0.276AsnCys: 0.276 ± 0.01	1.464AsnAsp: 1.464 ± 0.026	1.371AsnGlu: 1.371 ± 0.023	1.02AsnPhe: 1.02 ± 0.02	2.591AsnGly: 2.591 ± 0.034	0.594AsnHis: 0.594 ± 0.015	1.234AsnIle: 1.234 ± 0.018	0.667AsnLys: 0.667 ± 0.017	2.813AsnLeu: 2.813 ± 0.033	0.597AsnMet: 0.597 ± 0.014	0.84AsnAsn: 0.84 ± 0.018	1.875AsnPro: 1.875 ± 0.026	0.962AsnGln: 0.962 ± 0.022	1.862AsnArg: 1.862 ± 0.029	1.481AsnSer: 1.481 ± 0.027	1.506AsnThr: 1.506 ± 0.025	2.285AsnVal: 2.285 ± 0.03	0.457AsnTrp: 0.457 ± 0.012	0.747AsnTyr: 0.747 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	6.443ProAla: 6.443 ± 0.059	0.356ProCys: 0.356 ± 0.012	3.138ProAsp: 3.138 ± 0.035	2.922ProGlu: 2.922 ± 0.033	1.97ProPhe: 1.97 ± 0.025	4.102ProGly: 4.102 ± 0.043	1.278ProHis: 1.278 ± 0.023	2.042ProIle: 2.042 ± 0.027	1.478ProLys: 1.478 ± 0.024	5.12ProLeu: 5.12 ± 0.046	1.135ProMet: 1.135 ± 0.02	1.442ProAsn: 1.442 ± 0.021	2.455ProPro: 2.455 ± 0.036	1.931ProGln: 1.931 ± 0.033	2.893ProArg: 2.893 ± 0.035	2.909ProSer: 2.909 ± 0.034	2.611ProThr: 2.611 ± 0.027	4.241ProVal: 4.241 ± 0.04	0.678ProTrp: 0.678 ± 0.016	1.218ProTyr: 1.218 ± 0.023	0.0ProXaa: 0.0 ± 0.0
Gln	4.489GlnAla: 4.489 ± 0.052	0.279GlnCys: 0.279 ± 0.01	1.337GlnAsp: 1.337 ± 0.024	1.376GlnGlu: 1.376 ± 0.02	1.331GlnPhe: 1.331 ± 0.021	2.433GlnGly: 2.433 ± 0.032	0.966GlnHis: 0.966 ± 0.018	2.055GlnIle: 2.055 ± 0.028	1.132GlnLys: 1.132 ± 0.022	3.816GlnLeu: 3.816 ± 0.038	1.047GlnMet: 1.047 ± 0.021	0.93GlnAsn: 0.93 ± 0.021	2.062GlnPro: 2.062 ± 0.029	1.96GlnGln: 1.96 ± 0.036	2.977GlnArg: 2.977 ± 0.038	2.114GlnSer: 2.114 ± 0.029	2.05GlnThr: 2.05 ± 0.027	2.521GlnVal: 2.521 ± 0.032	0.577GlnTrp: 0.577 ± 0.015	0.933GlnTyr: 0.933 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	8.116ArgAla: 8.116 ± 0.07	0.651ArgCys: 0.651 ± 0.016	3.774ArgAsp: 3.774 ± 0.037	4.216ArgGlu: 4.216 ± 0.053	2.963ArgPhe: 2.963 ± 0.036	4.543ArgGly: 4.543 ± 0.041	1.907ArgHis: 1.907 ± 0.025	3.638ArgIle: 3.638 ± 0.034	2.248ArgLys: 2.248 ± 0.03	7.232ArgLeu: 7.232 ± 0.057	1.803ArgMet: 1.803 ± 0.024	1.994ArgAsn: 1.994 ± 0.026	3.021ArgPro: 3.021 ± 0.032	2.607ArgGln: 2.607 ± 0.033	5.368ArgArg: 5.368 ± 0.051	3.752ArgSer: 3.752 ± 0.038	3.477ArgThr: 3.477 ± 0.04	5.337ArgVal: 5.337 ± 0.043	1.075ArgTrp: 1.075 ± 0.021	1.981ArgTyr: 1.981 ± 0.028	0.0ArgXaa: 0.0 ± 0.0
Ser	7.12SerAla: 7.12 ± 0.047	0.486SerCys: 0.486 ± 0.013	2.901SerAsp: 2.901 ± 0.031	2.716SerGlu: 2.716 ± 0.032	2.314SerPhe: 2.314 ± 0.035	5.46SerGly: 5.46 ± 0.042	1.285SerHis: 1.285 ± 0.02	2.913SerIle: 2.913 ± 0.035	1.724SerLys: 1.724 ± 0.03	5.903SerLeu: 5.903 ± 0.052	1.494SerMet: 1.494 ± 0.022	1.727SerAsn: 1.727 ± 0.026	2.923SerPro: 2.923 ± 0.037	1.917SerGln: 1.917 ± 0.026	3.841SerArg: 3.841 ± 0.044	3.57SerSer: 3.57 ± 0.042	3.283SerThr: 3.283 ± 0.038	4.588SerVal: 4.588 ± 0.044	0.742SerTrp: 0.742 ± 0.016	1.334SerTyr: 1.334 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	6.063ThrAla: 6.063 ± 0.048	0.461ThrCys: 0.461 ± 0.013	2.619ThrAsp: 2.619 ± 0.033	2.365ThrGlu: 2.365 ± 0.032	1.997ThrPhe: 1.997 ± 0.024	4.848ThrGly: 4.848 ± 0.041	1.303ThrHis: 1.303 ± 0.022	2.654ThrIle: 2.654 ± 0.036	1.309ThrLys: 1.309 ± 0.024	6.453ThrLeu: 6.453 ± 0.058	1.209ThrMet: 1.209 ± 0.02	1.384ThrAsn: 1.384 ± 0.026	3.498ThrPro: 3.498 ± 0.034	1.994ThrGln: 1.994 ± 0.032	3.687ThrArg: 3.687 ± 0.038	3.073ThrSer: 3.073 ± 0.033	3.029ThrThr: 3.029 ± 0.048	4.411ThrVal: 4.411 ± 0.043	0.702ThrTrp: 0.702 ± 0.015	1.303ThrTyr: 1.303 ± 0.022	0.0ThrXaa: 0.0 ± 0.0
Val	9.506ValAla: 9.506 ± 0.069	0.864ValCys: 0.864 ± 0.018	4.284ValAsp: 4.284 ± 0.038	4.196ValGlu: 4.196 ± 0.043	2.954ValPhe: 2.954 ± 0.032	5.649ValGly: 5.649 ± 0.047	1.6ValHis: 1.6 ± 0.023	3.848ValIle: 3.848 ± 0.041	2.463ValLys: 2.463 ± 0.031	7.825ValLeu: 7.825 ± 0.062	1.904ValMet: 1.904 ± 0.024	2.267ValAsn: 2.267 ± 0.031	3.915ValPro: 3.915 ± 0.028	2.548ValGln: 2.548 ± 0.034	5.151ValArg: 5.151 ± 0.045	4.799ValSer: 4.799 ± 0.042	4.554ValThr: 4.554 ± 0.041	6.38ValVal: 6.38 ± 0.055	0.973ValTrp: 0.973 ± 0.019	1.713ValTyr: 1.713 ± 0.028	0.0ValXaa: 0.0 ± 0.0
Trp	1.193TrpAla: 1.193 ± 0.021	0.157TrpCys: 0.157 ± 0.007	0.632TrpAsp: 0.632 ± 0.015	0.514TrpGlu: 0.514 ± 0.015	0.561TrpPhe: 0.561 ± 0.014	0.889TrpGly: 0.889 ± 0.021	0.403TrpHis: 0.403 ± 0.011	0.7TrpIle: 0.7 ± 0.017	0.429TrpLys: 0.429 ± 0.012	1.953TrpLeu: 1.953 ± 0.031	0.392TrpMet: 0.392 ± 0.011	0.466TrpAsn: 0.466 ± 0.013	0.647TrpPro: 0.647 ± 0.015	0.648TrpGln: 0.648 ± 0.013	1.213TrpArg: 1.213 ± 0.022	0.82TrpSer: 0.82 ± 0.018	0.753TrpThr: 0.753 ± 0.016	0.915TrpVal: 0.915 ± 0.018	0.234TrpTrp: 0.234 ± 0.01	0.336TrpTyr: 0.336 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.8TyrAla: 2.8 ± 0.032	0.286TyrCys: 0.286 ± 0.011	1.324TyrAsp: 1.324 ± 0.023	1.228TyrGlu: 1.228 ± 0.023	1.039TyrPhe: 1.039 ± 0.02	2.128TyrGly: 2.128 ± 0.028	0.54TyrHis: 0.54 ± 0.014	0.886TyrIle: 0.886 ± 0.019	0.624TyrLys: 0.624 ± 0.015	2.577TyrLeu: 2.577 ± 0.029	0.454TyrMet: 0.454 ± 0.013	0.639TyrAsn: 0.639 ± 0.016	1.278TyrPro: 1.278 ± 0.022	0.894TyrGln: 0.894 ± 0.019	1.945TyrArg: 1.945 ± 0.026	1.366TyrSer: 1.366 ± 0.023	1.234TyrThr: 1.234 ± 0.02	1.904TyrVal: 1.904 ± 0.026	0.414TyrTrp: 0.414 ± 0.012	0.664TyrTyr: 0.664 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 9325 proteins (2853921 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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