Amino acid dipepetide frequency for Bovine papillomavirus type 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.206AlaAla: 8.206 ± 1.956
1.119AlaCys: 1.119 ± 0.634
1.119AlaAsp: 1.119 ± 0.489
5.595AlaGlu: 5.595 ± 0.984
3.357AlaPhe: 3.357 ± 1.282
1.119AlaGly: 1.119 ± 0.614
0.373AlaHis: 0.373 ± 0.334
1.492AlaIle: 1.492 ± 0.659
2.984AlaLys: 2.984 ± 0.775
3.73AlaLeu: 3.73 ± 0.671
0.746AlaMet: 0.746 ± 0.363
1.865AlaAsn: 1.865 ± 0.655
5.968AlaPro: 5.968 ± 1.287
3.73AlaGln: 3.73 ± 0.807
4.103AlaArg: 4.103 ± 1.283
5.595AlaSer: 5.595 ± 1.023
4.103AlaThr: 4.103 ± 0.724
3.73AlaVal: 3.73 ± 1.741
0.0AlaTrp: 0.0 ± 0.0
1.865AlaTyr: 1.865 ± 0.571
0.0AlaXaa: 0.0 ± 0.0
Cys
1.492CysAla: 1.492 ± 0.708
0.373CysCys: 0.373 ± 0.291
1.492CysAsp: 1.492 ± 0.946
1.492CysGlu: 1.492 ± 1.051
0.746CysPhe: 0.746 ± 0.581
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.492CysIle: 1.492 ± 0.742
0.373CysLys: 0.373 ± 0.291
2.238CysLeu: 2.238 ± 0.805
0.746CysMet: 0.746 ± 0.493
0.746CysAsn: 0.746 ± 0.456
1.492CysPro: 1.492 ± 0.696
0.0CysGln: 0.0 ± 0.0
0.746CysArg: 0.746 ± 0.378
1.865CysSer: 1.865 ± 1.059
2.238CysThr: 2.238 ± 0.622
0.0CysVal: 0.0 ± 0.0
0.373CysTrp: 0.373 ± 0.334
0.373CysTyr: 0.373 ± 0.462
0.0CysXaa: 0.0 ± 0.0
Asp
3.357AspAla: 3.357 ± 1.113
1.865AspCys: 1.865 ± 1.327
4.103AspAsp: 4.103 ± 0.837
2.984AspGlu: 2.984 ± 1.16
1.119AspPhe: 1.119 ± 0.639
3.73AspGly: 3.73 ± 1.087
1.492AspHis: 1.492 ± 1.135
3.357AspIle: 3.357 ± 1.302
1.492AspLys: 1.492 ± 0.63
4.476AspLeu: 4.476 ± 1.735
0.746AspMet: 0.746 ± 0.709
2.611AspAsn: 2.611 ± 0.718
5.968AspPro: 5.968 ± 1.414
4.849AspGln: 4.849 ± 1.484
2.611AspArg: 2.611 ± 1.008
4.476AspSer: 4.476 ± 0.915
4.849AspThr: 4.849 ± 0.918
3.357AspVal: 3.357 ± 0.882
0.746AspTrp: 0.746 ± 0.581
0.746AspTyr: 0.746 ± 0.395
0.0AspXaa: 0.0 ± 0.0
Glu
2.611GluAla: 2.611 ± 0.679
1.119GluCys: 1.119 ± 0.872
7.833GluAsp: 7.833 ± 1.761
5.222GluGlu: 5.222 ± 1.815
2.611GluPhe: 2.611 ± 0.718
2.238GluGly: 2.238 ± 1.224
1.119GluHis: 1.119 ± 0.488
3.73GluIle: 3.73 ± 0.924
1.492GluLys: 1.492 ± 0.642
3.357GluLeu: 3.357 ± 0.7
1.492GluMet: 1.492 ± 0.489
3.357GluAsn: 3.357 ± 0.905
1.492GluPro: 1.492 ± 0.489
3.73GluGln: 3.73 ± 0.998
2.611GluArg: 2.611 ± 0.779
2.984GluSer: 2.984 ± 1.065
5.222GluThr: 5.222 ± 1.903
4.849GluVal: 4.849 ± 1.441
0.373GluTrp: 0.373 ± 0.334
0.746GluTyr: 0.746 ± 0.395
0.0GluXaa: 0.0 ± 0.0
Phe
1.865PheAla: 1.865 ± 0.918
0.0PheCys: 0.0 ± 0.0
2.238PheAsp: 2.238 ± 0.489
2.238PheGlu: 2.238 ± 0.698
1.865PhePhe: 1.865 ± 0.503
2.984PheGly: 2.984 ± 0.802
0.373PheHis: 0.373 ± 0.445
2.238PheIle: 2.238 ± 0.852
2.238PheLys: 2.238 ± 0.844
7.833PheLeu: 7.833 ± 1.074
0.746PheMet: 0.746 ± 0.357
0.746PheAsn: 0.746 ± 0.378
1.865PhePro: 1.865 ± 0.614
2.611PheGln: 2.611 ± 0.825
3.73PheArg: 3.73 ± 0.682
1.119PheSer: 1.119 ± 0.639
1.865PheThr: 1.865 ± 0.915
4.103PheVal: 4.103 ± 0.798
1.865PheTrp: 1.865 ± 0.978
0.746PheTyr: 0.746 ± 0.667
0.0PheXaa: 0.0 ± 0.0
Gly
2.238GlyAla: 2.238 ± 0.878
2.238GlyCys: 2.238 ± 0.402
2.984GlyAsp: 2.984 ± 1.2
4.103GlyGlu: 4.103 ± 1.586
1.492GlyPhe: 1.492 ± 0.555
7.087GlyGly: 7.087 ± 2.618
4.103GlyHis: 4.103 ± 1.22
4.849GlyIle: 4.849 ± 0.976
2.984GlyLys: 2.984 ± 0.728
2.238GlyLeu: 2.238 ± 0.687
0.373GlyMet: 0.373 ± 0.334
2.611GlyAsn: 2.611 ± 0.677
7.087GlyPro: 7.087 ± 2.601
2.611GlyGln: 2.611 ± 0.452
5.968GlyArg: 5.968 ± 1.953
6.341GlySer: 6.341 ± 1.398
3.73GlyThr: 3.73 ± 0.888
3.73GlyVal: 3.73 ± 0.993
0.373GlyTrp: 0.373 ± 0.445
1.492GlyTyr: 1.492 ± 0.682
0.0GlyXaa: 0.0 ± 0.0
His
0.373HisAla: 0.373 ± 0.334
0.0HisCys: 0.0 ± 0.0
0.746HisAsp: 0.746 ± 0.413
0.746HisGlu: 0.746 ± 0.502
0.746HisPhe: 0.746 ± 0.508
2.611HisGly: 2.611 ± 1.215
0.0HisHis: 0.0 ± 0.0
1.492HisIle: 1.492 ± 0.726
1.865HisLys: 1.865 ± 0.859
1.492HisLeu: 1.492 ± 0.79
0.0HisMet: 0.0 ± 0.0
0.373HisAsn: 0.373 ± 0.291
3.357HisPro: 3.357 ± 1.094
1.119HisGln: 1.119 ± 0.946
2.238HisArg: 2.238 ± 0.556
1.865HisSer: 1.865 ± 0.839
1.492HisThr: 1.492 ± 0.407
2.238HisVal: 2.238 ± 0.489
1.119HisTrp: 1.119 ± 0.415
0.746HisTyr: 0.746 ± 0.378
0.0HisXaa: 0.0 ± 0.0
Ile
1.865IleAla: 1.865 ± 0.736
1.865IleCys: 1.865 ± 0.865
2.238IleAsp: 2.238 ± 0.975
4.103IleGlu: 4.103 ± 1.514
1.492IlePhe: 1.492 ± 0.642
2.611IleGly: 2.611 ± 1.082
0.746IleHis: 0.746 ± 0.542
3.73IleIle: 3.73 ± 1.158
2.984IleLys: 2.984 ± 0.724
4.849IleLeu: 4.849 ± 1.513
1.119IleMet: 1.119 ± 0.54
1.492IleAsn: 1.492 ± 0.489
2.611IlePro: 2.611 ± 0.86
0.746IleGln: 0.746 ± 0.363
1.492IleArg: 1.492 ± 0.576
2.984IleSer: 2.984 ± 0.677
3.73IleThr: 3.73 ± 1.333
2.984IleVal: 2.984 ± 1.232
0.0IleTrp: 0.0 ± 0.0
2.611IleTyr: 2.611 ± 1.562
0.0IleXaa: 0.0 ± 0.0
Lys
1.865LysAla: 1.865 ± 0.826
0.746LysCys: 0.746 ± 0.456
1.492LysAsp: 1.492 ± 0.612
1.865LysGlu: 1.865 ± 0.87
2.611LysPhe: 2.611 ± 1.169
4.476LysGly: 4.476 ± 1.427
2.238LysHis: 2.238 ± 0.825
2.238LysIle: 2.238 ± 0.857
1.865LysLys: 1.865 ± 0.77
4.103LysLeu: 4.103 ± 0.783
0.746LysMet: 0.746 ± 0.431
3.357LysAsn: 3.357 ± 0.882
1.492LysPro: 1.492 ± 0.381
0.746LysGln: 0.746 ± 0.363
3.73LysArg: 3.73 ± 1.016
5.595LysSer: 5.595 ± 1.646
2.238LysThr: 2.238 ± 0.594
0.746LysVal: 0.746 ± 0.667
1.119LysTrp: 1.119 ± 0.427
1.865LysTyr: 1.865 ± 0.508
0.0LysXaa: 0.0 ± 0.0
Leu
7.087LeuAla: 7.087 ± 1.618
2.238LeuCys: 2.238 ± 0.963
5.595LeuAsp: 5.595 ± 1.756
5.595LeuGlu: 5.595 ± 1.057
4.476LeuPhe: 4.476 ± 0.831
4.849LeuGly: 4.849 ± 1.116
2.611LeuHis: 2.611 ± 1.167
2.984LeuIle: 2.984 ± 0.789
5.595LeuLys: 5.595 ± 0.711
11.936LeuLeu: 11.936 ± 4.397
2.611LeuMet: 2.611 ± 0.89
2.611LeuAsn: 2.611 ± 1.113
5.222LeuPro: 5.222 ± 1.197
4.476LeuGln: 4.476 ± 1.115
4.103LeuArg: 4.103 ± 1.194
5.968LeuSer: 5.968 ± 2.192
2.611LeuThr: 2.611 ± 0.853
5.595LeuVal: 5.595 ± 1.502
2.238LeuTrp: 2.238 ± 1.024
2.611LeuTyr: 2.611 ± 0.634
0.0LeuXaa: 0.0 ± 0.0
Met
1.119MetAla: 1.119 ± 0.558
0.373MetCys: 0.373 ± 0.334
0.746MetAsp: 0.746 ± 0.363
1.119MetGlu: 1.119 ± 0.733
1.119MetPhe: 1.119 ± 0.634
0.746MetGly: 0.746 ± 0.363
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.492MetLys: 1.492 ± 0.822
1.865MetLeu: 1.865 ± 0.659
0.373MetMet: 0.373 ± 0.373
1.119MetAsn: 1.119 ± 0.702
0.0MetPro: 0.0 ± 0.0
1.119MetGln: 1.119 ± 0.427
1.119MetArg: 1.119 ± 0.57
3.357MetSer: 3.357 ± 1.159
0.746MetThr: 0.746 ± 0.363
0.746MetVal: 0.746 ± 0.358
0.0MetTrp: 0.0 ± 0.0
0.373MetTyr: 0.373 ± 0.334
0.0MetXaa: 0.0 ± 0.0
Asn
2.238AsnAla: 2.238 ± 1.395
0.746AsnCys: 0.746 ± 0.525
1.865AsnAsp: 1.865 ± 0.647
2.238AsnGlu: 2.238 ± 0.975
2.238AsnPhe: 2.238 ± 0.784
3.73AsnGly: 3.73 ± 1.305
0.0AsnHis: 0.0 ± 0.0
1.865AsnIle: 1.865 ± 0.6
2.611AsnLys: 2.611 ± 0.806
1.865AsnLeu: 1.865 ± 0.742
1.119AsnMet: 1.119 ± 0.743
3.73AsnAsn: 3.73 ± 1.901
1.492AsnPro: 1.492 ± 0.647
2.238AsnGln: 2.238 ± 0.934
2.984AsnArg: 2.984 ± 0.592
2.984AsnSer: 2.984 ± 0.955
2.984AsnThr: 2.984 ± 0.57
2.238AsnVal: 2.238 ± 0.63
0.746AsnTrp: 0.746 ± 0.456
0.373AsnTyr: 0.373 ± 0.316
0.0AsnXaa: 0.0 ± 0.0
Pro
3.73ProAla: 3.73 ± 1.099
0.746ProCys: 0.746 ± 0.484
5.595ProAsp: 5.595 ± 1.329
4.849ProGlu: 4.849 ± 1.355
2.238ProPhe: 2.238 ± 0.767
6.341ProGly: 6.341 ± 1.839
2.611ProHis: 2.611 ± 0.936
3.357ProIle: 3.357 ± 1.484
4.103ProLys: 4.103 ± 1.413
4.103ProLeu: 4.103 ± 1.07
1.119ProMet: 1.119 ± 0.465
3.357ProAsn: 3.357 ± 0.938
10.817ProPro: 10.817 ± 1.851
1.119ProGln: 1.119 ± 0.734
2.238ProArg: 2.238 ± 0.999
5.595ProSer: 5.595 ± 1.255
4.103ProThr: 4.103 ± 0.894
3.357ProVal: 3.357 ± 1.299
0.373ProTrp: 0.373 ± 0.316
1.865ProTyr: 1.865 ± 1.079
0.0ProXaa: 0.0 ± 0.0
Gln
1.865GlnAla: 1.865 ± 0.77
0.373GlnCys: 0.373 ± 0.291
2.611GlnAsp: 2.611 ± 0.934
2.611GlnGlu: 2.611 ± 0.808
0.373GlnPhe: 0.373 ± 0.334
4.103GlnGly: 4.103 ± 1.16
0.373GlnHis: 0.373 ± 0.316
3.357GlnIle: 3.357 ± 1.383
1.119GlnLys: 1.119 ± 0.391
3.357GlnLeu: 3.357 ± 0.91
1.119GlnMet: 1.119 ± 0.634
0.746GlnAsn: 0.746 ± 0.358
2.611GlnPro: 2.611 ± 0.452
3.357GlnGln: 3.357 ± 0.737
2.984GlnArg: 2.984 ± 0.563
2.984GlnSer: 2.984 ± 1.082
2.238GlnThr: 2.238 ± 0.362
2.611GlnVal: 2.611 ± 0.694
0.746GlnTrp: 0.746 ± 0.363
1.492GlnTyr: 1.492 ± 1.012
0.0GlnXaa: 0.0 ± 0.0
Arg
5.595ArgAla: 5.595 ± 0.886
1.119ArgCys: 1.119 ± 0.567
3.73ArgAsp: 3.73 ± 1.136
2.238ArgGlu: 2.238 ± 0.641
1.865ArgPhe: 1.865 ± 0.847
7.087ArgGly: 7.087 ± 2.094
3.357ArgHis: 3.357 ± 0.496
1.492ArgIle: 1.492 ± 0.533
1.865ArgLys: 1.865 ± 0.574
6.714ArgLeu: 6.714 ± 0.596
0.746ArgMet: 0.746 ± 0.493
2.238ArgAsn: 2.238 ± 0.764
4.476ArgPro: 4.476 ± 1.119
0.746ArgGln: 0.746 ± 0.363
9.325ArgArg: 9.325 ± 3.269
8.579ArgSer: 8.579 ± 4.059
5.222ArgThr: 5.222 ± 1.285
2.984ArgVal: 2.984 ± 0.979
0.0ArgTrp: 0.0 ± 0.0
1.119ArgTyr: 1.119 ± 0.327
0.0ArgXaa: 0.0 ± 0.0
Ser
5.968SerAla: 5.968 ± 1.26
0.0SerCys: 0.0 ± 0.0
3.73SerAsp: 3.73 ± 0.657
3.357SerGlu: 3.357 ± 1.115
7.087SerPhe: 7.087 ± 1.071
7.087SerGly: 7.087 ± 1.775
1.492SerHis: 1.492 ± 0.618
1.865SerIle: 1.865 ± 0.615
3.357SerLys: 3.357 ± 0.429
11.19SerLeu: 11.19 ± 2.381
1.865SerMet: 1.865 ± 0.686
1.865SerAsn: 1.865 ± 0.874
5.595SerPro: 5.595 ± 1.496
2.238SerGln: 2.238 ± 1.134
11.19SerArg: 11.19 ± 3.91
7.833SerSer: 7.833 ± 1.702
2.984SerThr: 2.984 ± 1.212
2.238SerVal: 2.238 ± 0.752
1.865SerTrp: 1.865 ± 0.313
1.492SerTyr: 1.492 ± 0.604
0.0SerXaa: 0.0 ± 0.0
Thr
2.238ThrAla: 2.238 ± 0.878
2.238ThrCys: 2.238 ± 0.955
2.984ThrAsp: 2.984 ± 1.277
2.984ThrGlu: 2.984 ± 1.033
4.476ThrPhe: 4.476 ± 0.856
4.476ThrGly: 4.476 ± 0.794
1.119ThrHis: 1.119 ± 0.57
3.357ThrIle: 3.357 ± 1.164
1.865ThrLys: 1.865 ± 0.538
7.087ThrLeu: 7.087 ± 2.0
0.373ThrMet: 0.373 ± 0.435
1.865ThrAsn: 1.865 ± 0.756
4.849ThrPro: 4.849 ± 1.661
1.119ThrGln: 1.119 ± 0.495
6.341ThrArg: 6.341 ± 0.981
5.968ThrSer: 5.968 ± 1.584
3.357ThrThr: 3.357 ± 0.984
4.103ThrVal: 4.103 ± 1.516
1.119ThrTrp: 1.119 ± 0.477
1.865ThrTyr: 1.865 ± 0.367
0.0ThrXaa: 0.0 ± 0.0
Val
3.357ValAla: 3.357 ± 0.768
1.119ValCys: 1.119 ± 0.946
4.849ValAsp: 4.849 ± 0.837
1.865ValGlu: 1.865 ± 0.841
1.492ValPhe: 1.492 ± 0.533
2.984ValGly: 2.984 ± 0.436
1.865ValHis: 1.865 ± 0.928
1.865ValIle: 1.865 ± 0.857
3.357ValLys: 3.357 ± 0.737
3.357ValLeu: 3.357 ± 0.429
1.119ValMet: 1.119 ± 0.473
2.238ValAsn: 2.238 ± 0.593
3.73ValPro: 3.73 ± 1.13
3.357ValGln: 3.357 ± 0.798
2.611ValArg: 2.611 ± 1.423
5.595ValSer: 5.595 ± 1.538
5.595ValThr: 5.595 ± 1.674
1.492ValVal: 1.492 ± 0.647
0.373ValTrp: 0.373 ± 0.334
1.865ValTyr: 1.865 ± 0.603
0.0ValXaa: 0.0 ± 0.0
Trp
1.492TrpAla: 1.492 ± 0.407
0.0TrpCys: 0.0 ± 0.0
1.492TrpAsp: 1.492 ± 0.879
1.492TrpGlu: 1.492 ± 0.489
0.373TrpPhe: 0.373 ± 0.318
0.0TrpGly: 0.0 ± 0.0
0.373TrpHis: 0.373 ± 0.316
1.119TrpIle: 1.119 ± 0.567
1.119TrpLys: 1.119 ± 0.872
1.119TrpLeu: 1.119 ± 0.552
0.0TrpMet: 0.0 ± 0.0
1.119TrpAsn: 1.119 ± 0.634
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
1.492TrpSer: 1.492 ± 0.483
1.865TrpThr: 1.865 ± 1.047
1.119TrpVal: 1.119 ± 0.54
0.373TrpTrp: 0.373 ± 0.291
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.238TyrAla: 2.238 ± 0.82
0.0TyrCys: 0.0 ± 0.0
1.865TyrAsp: 1.865 ± 0.923
1.492TyrGlu: 1.492 ± 0.791
1.492TyrPhe: 1.492 ± 0.641
0.373TyrGly: 0.373 ± 0.291
0.373TyrHis: 0.373 ± 0.334
0.373TyrIle: 0.373 ± 0.291
0.373TyrLys: 0.373 ± 0.291
4.103TyrLeu: 4.103 ± 1.735
0.0TyrMet: 0.0 ± 0.0
2.238TyrAsn: 2.238 ± 0.725
1.492TyrPro: 1.492 ± 0.611
1.119TyrGln: 1.119 ± 0.362
0.373TyrArg: 0.373 ± 0.334
1.119TyrSer: 1.119 ± 0.586
2.611TyrThr: 2.611 ± 0.983
1.865TyrVal: 1.865 ± 0.609
0.746TyrTrp: 0.746 ± 0.5
2.984TyrTyr: 2.984 ± 0.868
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 9 proteins (2682 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski