Amino acid dipepetide frequency for Lachancea dasiensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.388AlaAla: 5.388 ± 0.068	0.864AlaCys: 0.864 ± 0.021	3.301AlaAsp: 3.301 ± 0.037	4.017AlaGlu: 4.017 ± 0.045	2.698AlaPhe: 2.698 ± 0.04	3.873AlaGly: 3.873 ± 0.051	1.521AlaHis: 1.521 ± 0.026	3.813AlaIle: 3.813 ± 0.049	4.332AlaLys: 4.332 ± 0.048	6.86AlaLeu: 6.86 ± 0.062	1.522AlaMet: 1.522 ± 0.024	3.008AlaAsn: 3.008 ± 0.035	3.014AlaPro: 3.014 ± 0.051	2.97AlaGln: 2.97 ± 0.043	3.306AlaArg: 3.306 ± 0.042	6.105AlaSer: 6.105 ± 0.061	4.123AlaThr: 4.123 ± 0.05	4.208AlaVal: 4.208 ± 0.046	0.626AlaTrp: 0.626 ± 0.017	1.807AlaTyr: 1.807 ± 0.032	0.0AlaXaa: 0.0 ± 0.0
Cys	0.814CysAla: 0.814 ± 0.022	0.29CysCys: 0.29 ± 0.011	0.747CysAsp: 0.747 ± 0.018	0.67CysGlu: 0.67 ± 0.018	0.681CysPhe: 0.681 ± 0.017	0.952CysGly: 0.952 ± 0.023	0.371CysHis: 0.371 ± 0.013	0.825CysIle: 0.825 ± 0.02	0.68CysLys: 0.68 ± 0.016	1.35CysLeu: 1.35 ± 0.029	0.276CysMet: 0.276 ± 0.011	0.547CysAsn: 0.547 ± 0.018	0.534CysPro: 0.534 ± 0.018	0.518CysGln: 0.518 ± 0.015	0.614CysArg: 0.614 ± 0.014	1.136CysSer: 1.136 ± 0.025	0.629CysThr: 0.629 ± 0.016	0.94CysVal: 0.94 ± 0.02	0.183CysTrp: 0.183 ± 0.008	0.476CysTyr: 0.476 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	3.736AspAla: 3.736 ± 0.041	0.684AspCys: 0.684 ± 0.02	4.15AspAsp: 4.15 ± 0.059	4.739AspGlu: 4.739 ± 0.057	2.77AspPhe: 2.77 ± 0.037	3.209AspGly: 3.209 ± 0.041	1.259AspHis: 1.259 ± 0.022	3.383AspIle: 3.383 ± 0.039	3.014AspLys: 3.014 ± 0.039	5.835AspLeu: 5.835 ± 0.057	1.144AspMet: 1.144 ± 0.024	2.445AspAsn: 2.445 ± 0.033	2.601AspPro: 2.601 ± 0.038	2.145AspGln: 2.145 ± 0.029	2.41AspArg: 2.41 ± 0.035	4.789AspSer: 4.789 ± 0.049	2.805AspThr: 2.805 ± 0.035	3.821AspVal: 3.821 ± 0.04	0.658AspTrp: 0.658 ± 0.016	2.007AspTyr: 2.007 ± 0.026	0.0AspXaa: 0.0 ± 0.0
Glu	4.204GluAla: 4.204 ± 0.049	0.709GluCys: 0.709 ± 0.019	4.205GluAsp: 4.205 ± 0.054	5.489GluGlu: 5.489 ± 0.073	2.692GluPhe: 2.692 ± 0.036	3.121GluGly: 3.121 ± 0.038	1.415GluHis: 1.415 ± 0.026	3.781GluIle: 3.781 ± 0.042	4.418GluLys: 4.418 ± 0.047	6.865GluLeu: 6.865 ± 0.06	1.401GluMet: 1.401 ± 0.027	3.451GluAsn: 3.451 ± 0.043	2.285GluPro: 2.285 ± 0.037	2.762GluGln: 2.762 ± 0.035	3.384GluArg: 3.384 ± 0.042	5.053GluSer: 5.053 ± 0.05	3.46GluThr: 3.46 ± 0.043	3.872GluVal: 3.872 ± 0.05	0.703GluTrp: 0.703 ± 0.017	2.019GluTyr: 2.019 ± 0.029	0.0GluXaa: 0.0 ± 0.0
Phe	2.77PheAla: 2.77 ± 0.037	0.585PheCys: 0.585 ± 0.016	2.741PheAsp: 2.741 ± 0.037	2.922PheGlu: 2.922 ± 0.038	1.965PhePhe: 1.965 ± 0.037	2.805PheGly: 2.805 ± 0.043	1.023PheHis: 1.023 ± 0.022	2.258PheIle: 2.258 ± 0.037	2.643PheLys: 2.643 ± 0.038	4.204PheLeu: 4.204 ± 0.049	0.937PheMet: 0.937 ± 0.02	2.064PheAsn: 2.064 ± 0.032	1.819PhePro: 1.819 ± 0.026	1.991PheGln: 1.991 ± 0.031	1.874PheArg: 1.874 ± 0.029	3.672PheSer: 3.672 ± 0.038	2.376PheThr: 2.376 ± 0.032	2.876PheVal: 2.876 ± 0.037	0.535PheTrp: 0.535 ± 0.015	1.471PheTyr: 1.471 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	3.828GlyAla: 3.828 ± 0.048	0.82GlyCys: 0.82 ± 0.02	3.104GlyAsp: 3.104 ± 0.04	3.23GlyGlu: 3.23 ± 0.039	2.694GlyPhe: 2.694 ± 0.039	3.885GlyGly: 3.885 ± 0.05	1.396GlyHis: 1.396 ± 0.025	3.297GlyIle: 3.297 ± 0.041	3.516GlyLys: 3.516 ± 0.046	5.332GlyLeu: 5.332 ± 0.056	1.144GlyMet: 1.144 ± 0.022	2.633GlyAsn: 2.633 ± 0.035	2.152GlyPro: 2.152 ± 0.031	2.137GlyGln: 2.137 ± 0.032	2.701GlyArg: 2.701 ± 0.036	5.588GlySer: 5.588 ± 0.049	3.235GlyThr: 3.235 ± 0.037	3.678GlyVal: 3.678 ± 0.051	0.654GlyTrp: 0.654 ± 0.018	1.842GlyTyr: 1.842 ± 0.031	0.0GlyXaa: 0.0 ± 0.0
His	1.377HisAla: 1.377 ± 0.023	0.356HisCys: 0.356 ± 0.014	1.3HisAsp: 1.3 ± 0.026	1.409HisGlu: 1.409 ± 0.022	1.07HisPhe: 1.07 ± 0.023	1.358HisGly: 1.358 ± 0.024	0.752HisHis: 0.752 ± 0.023	1.309HisIle: 1.309 ± 0.022	1.291HisLys: 1.291 ± 0.024	2.333HisLeu: 2.333 ± 0.035	0.45HisMet: 0.45 ± 0.013	1.069HisAsn: 1.069 ± 0.023	1.158HisPro: 1.158 ± 0.021	1.034HisGln: 1.034 ± 0.021	1.247HisArg: 1.247 ± 0.023	2.054HisSer: 2.054 ± 0.031	1.169HisThr: 1.169 ± 0.023	1.339HisVal: 1.339 ± 0.023	0.269HisTrp: 0.269 ± 0.01	0.789HisTyr: 0.789 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	3.671IleAla: 3.671 ± 0.04	0.815IleCys: 0.815 ± 0.021	3.419IleAsp: 3.419 ± 0.037	3.415IleGlu: 3.415 ± 0.034	2.462IlePhe: 2.462 ± 0.041	2.972IleGly: 2.972 ± 0.039	1.239IleHis: 1.239 ± 0.026	2.869IleIle: 2.869 ± 0.037	3.281IleLys: 3.281 ± 0.037	5.377IleLeu: 5.377 ± 0.061	1.167IleMet: 1.167 ± 0.02	2.48IleAsn: 2.48 ± 0.037	2.873IlePro: 2.873 ± 0.033	2.165IleGln: 2.165 ± 0.029	2.603IleArg: 2.603 ± 0.032	4.88IleSer: 4.88 ± 0.051	2.939IleThr: 2.939 ± 0.035	3.547IleVal: 3.547 ± 0.044	0.648IleTrp: 0.648 ± 0.017	1.715IleTyr: 1.715 ± 0.025	0.0IleXaa: 0.0 ± 0.0
Lys	3.947LysAla: 3.947 ± 0.047	0.759LysCys: 0.759 ± 0.019	3.396LysAsp: 3.396 ± 0.04	3.936LysGlu: 3.936 ± 0.049	2.748LysPhe: 2.748 ± 0.034	2.899LysGly: 2.899 ± 0.04	1.415LysHis: 1.415 ± 0.02	3.6LysIle: 3.6 ± 0.04	4.72LysLys: 4.72 ± 0.069	6.683LysLeu: 6.683 ± 0.054	1.304LysMet: 1.304 ± 0.023	3.174LysAsn: 3.174 ± 0.037	2.76LysPro: 2.76 ± 0.034	2.498LysGln: 2.498 ± 0.032	3.817LysArg: 3.817 ± 0.042	5.086LysSer: 5.086 ± 0.046	3.513LysThr: 3.513 ± 0.039	3.861LysVal: 3.861 ± 0.044	0.743LysTrp: 0.743 ± 0.02	2.059LysTyr: 2.059 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	6.805LeuAla: 6.805 ± 0.066	1.4LeuCys: 1.4 ± 0.023	5.648LeuAsp: 5.648 ± 0.051	6.738LeuGlu: 6.738 ± 0.068	3.999LeuPhe: 3.999 ± 0.047	5.283LeuGly: 5.283 ± 0.053	2.268LeuHis: 2.268 ± 0.03	4.95LeuIle: 4.95 ± 0.058	6.856LeuLys: 6.856 ± 0.057	9.758LeuLeu: 9.758 ± 0.095	2.028LeuMet: 2.028 ± 0.026	4.801LeuAsn: 4.801 ± 0.052	4.843LeuPro: 4.843 ± 0.045	4.723LeuGln: 4.723 ± 0.051	5.392LeuArg: 5.392 ± 0.052	8.591LeuSer: 8.591 ± 0.08	5.34LeuThr: 5.34 ± 0.05	5.961LeuVal: 5.961 ± 0.057	1.009LeuTrp: 1.009 ± 0.021	2.922LeuTyr: 2.922 ± 0.038	0.0LeuXaa: 0.0 ± 0.0
Met	1.675MetAla: 1.675 ± 0.028	0.312MetCys: 0.312 ± 0.011	1.241MetAsp: 1.241 ± 0.022	1.212MetGlu: 1.212 ± 0.024	0.83MetPhe: 0.83 ± 0.019	1.311MetGly: 1.311 ± 0.02	0.413MetHis: 0.413 ± 0.011	1.136MetIle: 1.136 ± 0.023	1.248MetLys: 1.248 ± 0.021	1.929MetLeu: 1.929 ± 0.027	0.463MetMet: 0.463 ± 0.014	1.009MetAsn: 1.009 ± 0.02	0.877MetPro: 0.877 ± 0.022	0.728MetGln: 0.728 ± 0.019	1.005MetArg: 1.005 ± 0.021	2.056MetSer: 2.056 ± 0.029	1.144MetThr: 1.144 ± 0.021	1.319MetVal: 1.319 ± 0.022	0.195MetTrp: 0.195 ± 0.008	0.57MetTyr: 0.57 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.19AsnAla: 3.19 ± 0.041	0.649AsnCys: 0.649 ± 0.016	2.827AsnAsp: 2.827 ± 0.037	3.049AsnGlu: 3.049 ± 0.036	2.162AsnPhe: 2.162 ± 0.034	3.004AsnGly: 3.004 ± 0.033	0.972AsnHis: 0.972 ± 0.021	2.627AsnIle: 2.627 ± 0.034	2.763AsnLys: 2.763 ± 0.036	4.645AsnLeu: 4.645 ± 0.052	0.974AsnMet: 0.974 ± 0.018	2.317AsnAsn: 2.317 ± 0.036	2.182AsnPro: 2.182 ± 0.026	1.707AsnGln: 1.707 ± 0.032	2.151AsnArg: 2.151 ± 0.029	4.382AsnSer: 4.382 ± 0.047	2.465AsnThr: 2.465 ± 0.032	3.083AsnVal: 3.083 ± 0.039	0.579AsnTrp: 0.579 ± 0.014	1.595AsnTyr: 1.595 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	2.995ProAla: 2.995 ± 0.04	0.405ProCys: 0.405 ± 0.014	2.357ProAsp: 2.357 ± 0.032	3.167ProGlu: 3.167 ± 0.041	1.914ProPhe: 1.914 ± 0.03	2.421ProGly: 2.421 ± 0.033	1.132ProHis: 1.132 ± 0.025	2.341ProIle: 2.341 ± 0.032	2.575ProLys: 2.575 ± 0.033	4.309ProLeu: 4.309 ± 0.041	0.825ProMet: 0.825 ± 0.019	2.032ProAsn: 2.032 ± 0.03	2.525ProPro: 2.525 ± 0.058	2.22ProGln: 2.22 ± 0.032	2.159ProArg: 2.159 ± 0.037	4.416ProSer: 4.416 ± 0.06	2.73ProThr: 2.73 ± 0.037	2.975ProVal: 2.975 ± 0.038	0.455ProTrp: 0.455 ± 0.014	1.255ProTyr: 1.255 ± 0.023	0.0ProXaa: 0.0 ± 0.0
Gln	2.67GlnAla: 2.67 ± 0.039	0.475GlnCys: 0.475 ± 0.015	2.417GlnAsp: 2.417 ± 0.034	3.052GlnGlu: 3.052 ± 0.041	1.765GlnPhe: 1.765 ± 0.026	2.159GlnGly: 2.159 ± 0.036	1.071GlnHis: 1.071 ± 0.02	2.261GlnIle: 2.261 ± 0.037	2.643GlnLys: 2.643 ± 0.036	4.465GlnLeu: 4.465 ± 0.049	0.866GlnMet: 0.866 ± 0.02	2.072GlnAsn: 2.072 ± 0.031	1.8GlnPro: 1.8 ± 0.033	2.922GlnGln: 2.922 ± 0.11	2.403GlnArg: 2.403 ± 0.035	3.274GlnSer: 3.274 ± 0.041	2.17GlnThr: 2.17 ± 0.031	2.544GlnVal: 2.544 ± 0.029	0.464GlnTrp: 0.464 ± 0.013	1.299GlnTyr: 1.299 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	3.38ArgAla: 3.38 ± 0.039	0.673ArgCys: 0.673 ± 0.016	2.826ArgAsp: 2.826 ± 0.033	3.325ArgGlu: 3.325 ± 0.036	2.193ArgPhe: 2.193 ± 0.032	2.643ArgGly: 2.643 ± 0.034	1.182ArgHis: 1.182 ± 0.023	2.788ArgIle: 2.788 ± 0.031	3.674ArgLys: 3.674 ± 0.041	4.931ArgLeu: 4.931 ± 0.048	1.023ArgMet: 1.023 ± 0.018	2.477ArgAsn: 2.477 ± 0.033	2.114ArgPro: 2.114 ± 0.034	2.184ArgGln: 2.184 ± 0.03	3.346ArgArg: 3.346 ± 0.048	4.311ArgSer: 4.311 ± 0.049	2.59ArgThr: 2.59 ± 0.03	2.858ArgVal: 2.858 ± 0.031	0.573ArgTrp: 0.573 ± 0.015	1.647ArgTyr: 1.647 ± 0.029	0.0ArgXaa: 0.0 ± 0.0
Ser	5.934SerAla: 5.934 ± 0.066	1.058SerCys: 1.058 ± 0.029	4.755SerAsp: 4.755 ± 0.053	5.182SerGlu: 5.182 ± 0.056	3.762SerPhe: 3.762 ± 0.046	5.463SerGly: 5.463 ± 0.063	2.081SerHis: 2.081 ± 0.032	4.748SerIle: 4.748 ± 0.047	5.557SerLys: 5.557 ± 0.054	8.482SerLeu: 8.482 ± 0.072	1.826SerMet: 1.826 ± 0.03	4.232SerAsn: 4.232 ± 0.049	4.13SerPro: 4.13 ± 0.058	3.883SerGln: 3.883 ± 0.043	4.531SerArg: 4.531 ± 0.049	10.295SerSer: 10.295 ± 0.186	5.484SerThr: 5.484 ± 0.072	5.162SerVal: 5.162 ± 0.046	0.927SerTrp: 0.927 ± 0.02	2.383SerTyr: 2.383 ± 0.034	0.0SerXaa: 0.0 ± 0.0
Thr	3.812ThrAla: 3.812 ± 0.045	0.724ThrCys: 0.724 ± 0.016	2.764ThrAsp: 2.764 ± 0.032	3.084ThrGlu: 3.084 ± 0.036	2.392ThrPhe: 2.392 ± 0.029	3.411ThrGly: 3.411 ± 0.039	1.238ThrHis: 1.238 ± 0.023	3.106ThrIle: 3.106 ± 0.031	3.342ThrLys: 3.342 ± 0.037	5.526ThrLeu: 5.526 ± 0.049	1.123ThrMet: 1.123 ± 0.021	2.58ThrAsn: 2.58 ± 0.031	2.873ThrPro: 2.873 ± 0.041	2.056ThrGln: 2.056 ± 0.031	2.632ThrArg: 2.632 ± 0.034	5.379ThrSer: 5.379 ± 0.066	3.486ThrThr: 3.486 ± 0.049	3.526ThrVal: 3.526 ± 0.043	0.596ThrTrp: 0.596 ± 0.017	1.545ThrTyr: 1.545 ± 0.025	0.0ThrXaa: 0.0 ± 0.0
Val	4.526ValAla: 4.526 ± 0.047	0.896ValCys: 0.896 ± 0.021	3.822ValAsp: 3.822 ± 0.036	4.171ValGlu: 4.171 ± 0.048	2.71ValPhe: 2.71 ± 0.038	3.582ValGly: 3.582 ± 0.044	1.345ValHis: 1.345 ± 0.022	3.287ValIle: 3.287 ± 0.038	3.812ValLys: 3.812 ± 0.041	6.186ValLeu: 6.186 ± 0.059	1.262ValMet: 1.262 ± 0.025	2.846ValAsn: 2.846 ± 0.034	3.056ValPro: 3.056 ± 0.037	2.33ValGln: 2.33 ± 0.038	2.963ValArg: 2.963 ± 0.035	5.414ValSer: 5.414 ± 0.057	3.392ValThr: 3.392 ± 0.038	4.416ValVal: 4.416 ± 0.047	0.671ValTrp: 0.671 ± 0.018	1.868ValTyr: 1.868 ± 0.03	0.0ValXaa: 0.0 ± 0.0
Trp	0.68TrpAla: 0.68 ± 0.019	0.264TrpCys: 0.264 ± 0.01	0.734TrpAsp: 0.734 ± 0.02	0.629TrpGlu: 0.629 ± 0.015	0.531TrpPhe: 0.531 ± 0.015	0.607TrpGly: 0.607 ± 0.018	0.25TrpHis: 0.25 ± 0.011	0.609TrpIle: 0.609 ± 0.017	0.784TrpLys: 0.784 ± 0.018	1.053TrpLeu: 1.053 ± 0.022	0.251TrpMet: 0.251 ± 0.009	0.593TrpAsn: 0.593 ± 0.018	0.365TrpPro: 0.365 ± 0.013	0.43TrpGln: 0.43 ± 0.013	0.623TrpArg: 0.623 ± 0.016	0.919TrpSer: 0.919 ± 0.021	0.568TrpThr: 0.568 ± 0.014	0.594TrpVal: 0.594 ± 0.016	0.176TrpTrp: 0.176 ± 0.009	0.376TrpTyr: 0.376 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.953TyrAla: 1.953 ± 0.029	0.495TyrCys: 0.495 ± 0.015	1.848TyrAsp: 1.848 ± 0.031	1.858TyrGlu: 1.858 ± 0.031	1.494TyrPhe: 1.494 ± 0.024	1.909TyrGly: 1.909 ± 0.033	0.789TyrHis: 0.789 ± 0.018	1.549TyrIle: 1.549 ± 0.028	1.771TyrLys: 1.771 ± 0.027	3.192TyrLeu: 3.192 ± 0.044	0.688TyrMet: 0.688 ± 0.016	1.49TyrAsn: 1.49 ± 0.029	1.248TyrPro: 1.248 ± 0.023	1.389TyrGln: 1.389 ± 0.026	1.577TyrArg: 1.577 ± 0.027	2.474TyrSer: 2.474 ± 0.036	1.577TyrThr: 1.577 ± 0.028	1.974TyrVal: 1.974 ± 0.03	0.372TyrTrp: 0.372 ± 0.013	1.181TyrTyr: 1.181 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5089 proteins (2476411 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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