Amino acid dipepetide frequency for Leishmania RNA virus 2 - 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.886AlaAla: 5.886 ± 1.429
3.27AlaCys: 3.27 ± 0.989
5.886AlaAsp: 5.886 ± 1.907
5.232AlaGlu: 5.232 ± 2.203
1.308AlaPhe: 1.308 ± 1.089
7.848AlaGly: 7.848 ± 5.057
4.578AlaHis: 4.578 ± 1.981
7.848AlaIle: 7.848 ± 4.289
3.924AlaLys: 3.924 ± 1.271
7.848AlaLeu: 7.848 ± 2.255
2.616AlaMet: 2.616 ± 0.794
0.654AlaAsn: 0.654 ± 0.502
5.232AlaPro: 5.232 ± 5.156
2.616AlaGln: 2.616 ± 1.102
3.924AlaArg: 3.924 ± 1.271
7.194AlaSer: 7.194 ± 1.727
4.578AlaThr: 4.578 ± 1.27
3.27AlaVal: 3.27 ± 1.789
1.962AlaTrp: 1.962 ± 1.506
3.27AlaTyr: 3.27 ± 1.59
0.0AlaXaa: 0.0 ± 0.0
Cys
3.27CysAla: 3.27 ± 1.59
0.654CysCys: 0.654 ± 0.502
3.27CysAsp: 3.27 ± 0.868
1.962CysGlu: 1.962 ± 1.634
0.654CysPhe: 0.654 ± 0.545
1.962CysGly: 1.962 ± 1.634
0.0CysHis: 0.0 ± 0.0
0.654CysIle: 0.654 ± 0.545
0.0CysLys: 0.0 ± 0.0
2.616CysLeu: 2.616 ± 1.102
0.654CysMet: 0.654 ± 0.545
1.962CysAsn: 1.962 ± 0.636
0.654CysPro: 0.654 ± 0.502
0.0CysGln: 0.0 ± 0.0
0.654CysArg: 0.654 ± 5.988
1.308CysSer: 1.308 ± 0.314
1.308CysThr: 1.308 ± 1.089
2.616CysVal: 2.616 ± 2.008
0.654CysTrp: 0.654 ± 0.545
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.27AspAla: 3.27 ± 5.366
1.308AspCys: 1.308 ± 0.314
3.27AspAsp: 3.27 ± 0.868
3.924AspGlu: 3.924 ± 0.942
3.27AspPhe: 3.27 ± 1.59
4.578AspGly: 4.578 ± 1.981
1.962AspHis: 1.962 ± 1.506
3.27AspIle: 3.27 ± 0.868
1.308AspLys: 1.308 ± 1.004
6.54AspLeu: 6.54 ± 2.358
0.0AspMet: 0.0 ± 0.0
2.616AspAsn: 2.616 ± 0.628
1.308AspPro: 1.308 ± 1.089
0.0AspGln: 0.0 ± 0.0
0.654AspArg: 0.654 ± 0.502
1.308AspSer: 1.308 ± 0.314
1.962AspThr: 1.962 ± 0.734
5.886AspVal: 5.886 ± 1.429
0.0AspTrp: 0.0 ± 0.0
3.924AspTyr: 3.924 ± 1.468
0.0AspXaa: 0.0 ± 0.0
Glu
6.54GluAla: 6.54 ± 1.57
1.308GluCys: 1.308 ± 1.089
2.616GluAsp: 2.616 ± 1.102
5.886GluGlu: 5.886 ± 1.429
1.308GluPhe: 1.308 ± 0.314
3.924GluGly: 3.924 ± 1.271
1.962GluHis: 1.962 ± 1.506
1.308GluIle: 1.308 ± 1.089
1.308GluLys: 1.308 ± 1.004
5.232GluLeu: 5.232 ± 2.203
1.308GluMet: 1.308 ± 0.314
1.962GluAsn: 1.962 ± 0.734
3.27GluPro: 3.27 ± 1.789
0.654GluGln: 0.654 ± 0.502
3.27GluArg: 3.27 ± 1.59
2.616GluSer: 2.616 ± 1.102
3.27GluThr: 3.27 ± 0.868
2.616GluVal: 2.616 ± 0.628
0.0GluTrp: 0.0 ± 0.0
3.27GluTyr: 3.27 ± 0.989
0.0GluXaa: 0.0 ± 0.0
Phe
1.308PheAla: 1.308 ± 0.314
0.0PheCys: 0.0 ± 0.0
2.616PheAsp: 2.616 ± 1.254
3.27PheGlu: 3.27 ± 2.509
0.0PhePhe: 0.0 ± 0.0
0.0PheGly: 0.0 ± 0.0
0.654PheHis: 0.654 ± 0.545
0.654PheIle: 0.654 ± 0.502
1.308PheLys: 1.308 ± 1.004
1.308PheLeu: 1.308 ± 1.004
1.308PheMet: 1.308 ± 0.314
2.616PheAsn: 2.616 ± 1.254
0.654PhePro: 0.654 ± 0.502
0.654PheGln: 0.654 ± 5.988
3.27PheArg: 3.27 ± 2.724
2.616PheSer: 2.616 ± 1.102
1.962PheThr: 1.962 ± 0.734
0.0PheVal: 0.0 ± 0.0
1.308PheTrp: 1.308 ± 0.314
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.924GlyAla: 3.924 ± 1.468
1.962GlyCys: 1.962 ± 0.636
3.924GlyAsp: 3.924 ± 1.468
1.962GlyGlu: 1.962 ± 0.636
0.0GlyPhe: 0.0 ± 0.0
5.886GlyGly: 5.886 ± 3.041
3.27GlyHis: 3.27 ± 0.868
5.232GlyIle: 5.232 ± 1.489
4.578GlyLys: 4.578 ± 5.137
4.578GlyLeu: 4.578 ± 2.869
1.308GlyMet: 1.308 ± 0.314
1.962GlyAsn: 1.962 ± 0.734
1.308GlyPro: 1.308 ± 1.089
2.616GlyGln: 2.616 ± 1.254
5.232GlyArg: 5.232 ± 1.713
1.308GlySer: 1.308 ± 0.314
7.194GlyThr: 7.194 ± 3.233
8.502GlyVal: 8.502 ± 2.353
1.308GlyTrp: 1.308 ± 5.851
1.962GlyTyr: 1.962 ± 0.636
0.0GlyXaa: 0.0 ± 0.0
His
3.27HisAla: 3.27 ± 0.868
0.654HisCys: 0.654 ± 0.502
1.308HisAsp: 1.308 ± 0.314
0.654HisGlu: 0.654 ± 0.545
0.654HisPhe: 0.654 ± 0.502
2.616HisGly: 2.616 ± 1.102
1.962HisHis: 1.962 ± 0.636
1.962HisIle: 1.962 ± 0.636
1.308HisLys: 1.308 ± 1.004
0.654HisLeu: 0.654 ± 0.545
1.308HisMet: 1.308 ± 1.089
2.616HisAsn: 2.616 ± 1.254
3.27HisPro: 3.27 ± 5.366
0.0HisGln: 0.0 ± 0.0
0.654HisArg: 0.654 ± 0.502
3.27HisSer: 3.27 ± 0.989
3.27HisThr: 3.27 ± 0.868
4.578HisVal: 4.578 ± 1.727
0.654HisTrp: 0.654 ± 0.545
3.27HisTyr: 3.27 ± 0.868
0.0HisXaa: 0.0 ± 0.0
Ile
7.194IleAla: 7.194 ± 3.673
0.0IleCys: 0.0 ± 0.0
0.654IleAsp: 0.654 ± 0.502
1.962IleGlu: 1.962 ± 0.636
1.308IlePhe: 1.308 ± 0.314
3.27IleGly: 3.27 ± 0.868
1.308IleHis: 1.308 ± 0.314
1.308IleIle: 1.308 ± 1.089
1.308IleLys: 1.308 ± 1.004
5.886IleLeu: 5.886 ± 10.902
1.308IleMet: 1.308 ± 1.004
2.616IleAsn: 2.616 ± 0.628
3.27IlePro: 3.27 ± 0.989
0.0IleGln: 0.0 ± 0.0
2.616IleArg: 2.616 ± 0.628
3.27IleSer: 3.27 ± 0.989
1.308IleThr: 1.308 ± 1.089
3.27IleVal: 3.27 ± 1.789
0.654IleTrp: 0.654 ± 0.545
3.27IleTyr: 3.27 ± 1.789
0.0IleXaa: 0.0 ± 0.0
Lys
1.308LysAla: 1.308 ± 0.314
1.962LysCys: 1.962 ± 0.636
1.308LysAsp: 1.308 ± 0.314
2.616LysGlu: 2.616 ± 1.102
0.0LysPhe: 0.0 ± 0.0
1.962LysGly: 1.962 ± 0.734
4.578LysHis: 4.578 ± 1.727
0.0LysIle: 0.0 ± 0.0
1.962LysLys: 1.962 ± 0.636
4.578LysLeu: 4.578 ± 3.513
1.308LysMet: 1.308 ± 0.314
0.654LysAsn: 0.654 ± 5.988
1.308LysPro: 1.308 ± 1.004
3.27LysGln: 3.27 ± 0.868
2.616LysArg: 2.616 ± 1.102
1.962LysSer: 1.962 ± 0.636
0.654LysThr: 0.654 ± 0.502
4.578LysVal: 4.578 ± 3.513
0.0LysTrp: 0.0 ± 0.0
3.924LysTyr: 3.924 ± 1.271
0.0LysXaa: 0.0 ± 0.0
Leu
5.886LeuAla: 5.886 ± 1.429
1.962LeuCys: 1.962 ± 0.636
3.924LeuAsp: 3.924 ± 1.271
5.232LeuGlu: 5.232 ± 1.489
3.27LeuPhe: 3.27 ± 0.989
3.27LeuGly: 3.27 ± 1.59
3.924LeuHis: 3.924 ± 1.468
1.962LeuIle: 1.962 ± 5.677
7.848LeuLys: 7.848 ± 2.002
9.156LeuLeu: 9.156 ± 2.28
1.962LeuMet: 1.962 ± 0.636
4.578LeuAsn: 4.578 ± 1.27
3.27LeuPro: 3.27 ± 0.989
0.654LeuGln: 0.654 ± 0.545
7.194LeuArg: 7.194 ± 3.673
7.194LeuSer: 7.194 ± 1.727
8.502LeuThr: 8.502 ± 5.23
3.924LeuVal: 3.924 ± 5.241
1.962LeuTrp: 1.962 ± 1.506
3.924LeuTyr: 3.924 ± 2.084
0.0LeuXaa: 0.0 ± 0.0
Met
3.27MetAla: 3.27 ± 0.868
0.0MetCys: 0.0 ± 0.0
1.962MetAsp: 1.962 ± 0.636
1.308MetGlu: 1.308 ± 0.314
1.308MetPhe: 1.308 ± 0.314
1.308MetGly: 1.308 ± 5.851
0.654MetHis: 0.654 ± 0.545
1.308MetIle: 1.308 ± 1.004
0.654MetLys: 0.654 ± 0.502
1.962MetLeu: 1.962 ± 0.636
1.308MetMet: 1.308 ± 0.314
1.308MetAsn: 1.308 ± 0.314
1.962MetPro: 1.962 ± 0.636
0.654MetGln: 0.654 ± 0.545
2.616MetArg: 2.616 ± 1.102
1.962MetSer: 1.962 ± 0.636
0.654MetThr: 0.654 ± 0.545
1.308MetVal: 1.308 ± 5.856
0.654MetTrp: 0.654 ± 0.545
1.308MetTyr: 1.308 ± 0.314
0.0MetXaa: 0.0 ± 0.0
Asn
4.578AsnAla: 4.578 ± 1.14
0.654AsnCys: 0.654 ± 0.545
1.308AsnAsp: 1.308 ± 1.089
1.308AsnGlu: 1.308 ± 1.004
0.0AsnPhe: 0.0 ± 0.0
2.616AsnGly: 2.616 ± 1.102
1.962AsnHis: 1.962 ± 0.734
3.27AsnIle: 3.27 ± 0.989
0.654AsnLys: 0.654 ± 0.502
1.962AsnLeu: 1.962 ± 1.634
0.654AsnMet: 0.654 ± 0.502
1.962AsnAsn: 1.962 ± 0.734
2.616AsnPro: 2.616 ± 2.008
0.654AsnGln: 0.654 ± 0.545
3.924AsnArg: 3.924 ± 5.439
1.962AsnSer: 1.962 ± 0.734
1.962AsnThr: 1.962 ± 0.636
7.194AsnVal: 7.194 ± 4.116
1.308AsnTrp: 1.308 ± 1.004
1.962AsnTyr: 1.962 ± 0.734
0.0AsnXaa: 0.0 ± 0.0
Pro
5.232ProAla: 5.232 ± 11.451
1.308ProCys: 1.308 ± 0.314
1.308ProAsp: 1.308 ± 0.314
1.308ProGlu: 1.308 ± 0.314
0.0ProPhe: 0.0 ± 0.0
1.962ProGly: 1.962 ± 0.734
1.308ProHis: 1.308 ± 1.004
2.616ProIle: 2.616 ± 1.254
0.654ProLys: 0.654 ± 0.502
3.27ProLeu: 3.27 ± 0.868
0.654ProMet: 0.654 ± 0.502
2.616ProAsn: 2.616 ± 0.628
1.308ProPro: 1.308 ± 1.089
3.924ProGln: 3.924 ± 2.328
1.308ProArg: 1.308 ± 0.314
1.308ProSer: 1.308 ± 1.004
3.924ProThr: 3.924 ± 2.328
5.886ProVal: 5.886 ± 4.746
1.308ProTrp: 1.308 ± 1.089
1.962ProTyr: 1.962 ± 5.765
0.0ProXaa: 0.0 ± 0.0
Gln
2.616GlnAla: 2.616 ± 2.179
0.654GlnCys: 0.654 ± 0.502
0.0GlnAsp: 0.0 ± 0.0
0.654GlnGlu: 0.654 ± 0.545
0.0GlnPhe: 0.0 ± 0.0
1.308GlnGly: 1.308 ± 0.314
1.308GlnHis: 1.308 ± 1.004
0.0GlnIle: 0.0 ± 0.0
1.308GlnLys: 1.308 ± 1.004
0.654GlnLeu: 0.654 ± 0.545
1.962GlnMet: 1.962 ± 0.734
1.308GlnAsn: 1.308 ± 0.314
3.924GlnPro: 3.924 ± 2.328
0.0GlnGln: 0.0 ± 0.0
1.962GlnArg: 1.962 ± 0.734
3.27GlnSer: 3.27 ± 5.451
0.654GlnThr: 0.654 ± 0.545
0.654GlnVal: 0.654 ± 0.502
0.654GlnTrp: 0.654 ± 0.502
1.308GlnTyr: 1.308 ± 1.004
0.0GlnXaa: 0.0 ± 0.0
Arg
7.194ArgAla: 7.194 ± 1.727
1.308ArgCys: 1.308 ± 1.004
4.578ArgAsp: 4.578 ± 1.981
2.616ArgGlu: 2.616 ± 1.102
1.962ArgPhe: 1.962 ± 0.734
5.886ArgGly: 5.886 ± 2.202
1.962ArgHis: 1.962 ± 0.734
3.27ArgIle: 3.27 ± 0.989
4.578ArgLys: 4.578 ± 2.582
3.924ArgLeu: 3.924 ± 2.084
0.654ArgMet: 0.654 ± 0.502
1.308ArgAsn: 1.308 ± 1.004
2.616ArgPro: 2.616 ± 5.545
1.962ArgGln: 1.962 ± 0.636
3.27ArgArg: 3.27 ± 0.989
3.27ArgSer: 3.27 ± 5.466
5.232ArgThr: 5.232 ± 2.203
7.848ArgVal: 7.848 ± 4.289
0.654ArgTrp: 0.654 ± 0.502
0.0ArgTyr: 0.0 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
2.616SerAla: 2.616 ± 1.254
1.308SerCys: 1.308 ± 1.004
3.924SerAsp: 3.924 ± 2.084
1.962SerGlu: 1.962 ± 0.636
1.308SerPhe: 1.308 ± 0.314
4.578SerGly: 4.578 ± 1.14
0.654SerHis: 0.654 ± 0.545
1.962SerIle: 1.962 ± 0.734
0.654SerLys: 0.654 ± 0.545
7.194SerLeu: 7.194 ± 4.437
2.616SerMet: 2.616 ± 1.102
1.308SerAsn: 1.308 ± 1.089
1.308SerPro: 1.308 ± 0.314
1.962SerGln: 1.962 ± 1.506
7.194SerArg: 7.194 ± 1.727
5.232SerSer: 5.232 ± 3.08
5.886SerThr: 5.886 ± 1.564
7.194SerVal: 7.194 ± 4.437
0.654SerTrp: 0.654 ± 0.502
3.924SerTyr: 3.924 ± 0.942
0.0SerXaa: 0.0 ± 0.0
Thr
6.54ThrAla: 6.54 ± 2.712
1.308ThrCys: 1.308 ± 1.089
1.308ThrAsp: 1.308 ± 0.314
1.962ThrGlu: 1.962 ± 1.634
1.962ThrPhe: 1.962 ± 0.636
5.886ThrGly: 5.886 ± 3.041
0.654ThrHis: 0.654 ± 0.502
1.962ThrIle: 1.962 ± 0.636
4.578ThrLys: 4.578 ± 1.727
5.886ThrLeu: 5.886 ± 1.429
2.616ThrMet: 2.616 ± 0.628
4.578ThrAsn: 4.578 ± 1.981
1.962ThrPro: 1.962 ± 5.677
2.616ThrGln: 2.616 ± 0.628
3.924ThrArg: 3.924 ± 0.942
4.578ThrSer: 4.578 ± 2.869
2.616ThrThr: 2.616 ± 1.254
5.886ThrVal: 5.886 ± 3.955
0.654ThrTrp: 0.654 ± 0.545
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
8.502ValAla: 8.502 ± 2.03
3.27ValCys: 3.27 ± 5.466
2.616ValAsp: 2.616 ± 5.542
8.502ValGlu: 8.502 ± 2.169
5.886ValPhe: 5.886 ± 4.824
3.924ValGly: 3.924 ± 1.468
2.616ValHis: 2.616 ± 0.628
3.924ValIle: 3.924 ± 2.084
1.962ValLys: 1.962 ± 0.734
10.464ValLeu: 10.464 ± 2.832
1.962ValMet: 1.962 ± 5.731
3.924ValAsn: 3.924 ± 1.271
2.616ValPro: 2.616 ± 1.254
0.654ValGln: 0.654 ± 0.502
6.54ValArg: 6.54 ± 4.783
5.232ValSer: 5.232 ± 1.256
3.924ValThr: 3.924 ± 1.468
7.848ValVal: 7.848 ± 2.002
0.0ValTrp: 0.0 ± 0.0
5.232ValTyr: 5.232 ± 4.916
0.0ValXaa: 0.0 ± 0.0
Trp
0.654TrpAla: 0.654 ± 0.502
0.654TrpCys: 0.654 ± 0.502
1.962TrpAsp: 1.962 ± 0.734
0.0TrpGlu: 0.0 ± 0.0
1.308TrpPhe: 1.308 ± 0.314
1.308TrpGly: 1.308 ± 0.314
1.308TrpHis: 1.308 ± 5.856
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.308TrpLeu: 1.308 ± 1.004
0.654TrpMet: 0.654 ± 0.502
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.308TrpArg: 1.308 ± 0.314
0.654TrpSer: 0.654 ± 0.502
1.308TrpThr: 1.308 ± 1.089
1.962TrpVal: 1.962 ± 0.734
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
6.54TyrAla: 6.54 ± 2.358
1.308TyrCys: 1.308 ± 1.089
2.616TyrAsp: 2.616 ± 1.102
1.308TyrGlu: 1.308 ± 0.314
0.0TyrPhe: 0.0 ± 0.0
3.924TyrGly: 3.924 ± 1.271
1.308TyrHis: 1.308 ± 0.314
3.27TyrIle: 3.27 ± 1.789
0.654TyrLys: 0.654 ± 0.502
4.578TyrLeu: 4.578 ± 1.14
0.654TyrMet: 0.654 ± 4.001
1.962TyrAsn: 1.962 ± 0.734
1.308TyrPro: 1.308 ± 0.314
1.308TyrGln: 1.308 ± 1.089
1.962TyrArg: 1.962 ± 0.636
3.924TyrSer: 3.924 ± 2.084
1.308TyrThr: 1.308 ± 1.089
4.578TyrVal: 4.578 ± 5.406
0.0TyrTrp: 0.0 ± 0.0
1.962TyrTyr: 1.962 ± 5.677
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1530 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski