Amino acid dipepetide frequency for CRESS virus sp.

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.091AlaAla: 8.091 ± 0.812
1.618AlaCys: 1.618 ± 1.068
0.0AlaAsp: 0.0 ± 0.0
1.618AlaGlu: 1.618 ± 1.068
3.236AlaPhe: 3.236 ± 0.128
6.472AlaGly: 6.472 ± 0.257
1.618AlaHis: 1.618 ± 1.197
1.618AlaIle: 1.618 ± 1.197
3.236AlaLys: 3.236 ± 0.128
4.854AlaLeu: 4.854 ± 3.59
1.618AlaMet: 1.618 ± 1.068
0.0AlaAsn: 0.0 ± 0.0
4.854AlaPro: 4.854 ± 1.325
0.0AlaGln: 0.0 ± 0.0
3.236AlaArg: 3.236 ± 2.393
3.236AlaSer: 3.236 ± 0.128
1.618AlaThr: 1.618 ± 1.197
3.236AlaVal: 3.236 ± 0.128
4.854AlaTrp: 4.854 ± 0.94
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.618CysAsp: 1.618 ± 1.068
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
8.091CysGly: 8.091 ± 3.077
0.0CysHis: 0.0 ± 0.0
3.236CysIle: 3.236 ± 2.137
3.236CysLys: 3.236 ± 2.137
0.0CysLeu: 0.0 ± 0.0
1.618CysMet: 1.618 ± 1.068
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
3.236CysThr: 3.236 ± 0.128
1.618CysVal: 1.618 ± 1.068
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
0.0AspAla: 0.0 ± 0.0
0.0AspCys: 0.0 ± 0.0
1.618AspAsp: 1.618 ± 1.197
8.091AspGlu: 8.091 ± 5.342
4.854AspPhe: 4.854 ± 1.325
3.236AspGly: 3.236 ± 2.137
0.0AspHis: 0.0 ± 0.0
0.0AspIle: 0.0 ± 0.0
3.236AspLys: 3.236 ± 0.128
3.236AspLeu: 3.236 ± 2.137
0.0AspMet: 0.0 ± 0.0
1.618AspAsn: 1.618 ± 1.197
3.236AspPro: 3.236 ± 2.393
0.0AspGln: 0.0 ± 0.0
0.0AspArg: 0.0 ± 0.0
1.618AspSer: 1.618 ± 1.068
4.854AspThr: 4.854 ± 0.94
0.0AspVal: 0.0 ± 0.0
3.236AspTrp: 3.236 ± 0.128
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
1.618GluAla: 1.618 ± 1.197
1.618GluCys: 1.618 ± 1.197
0.0GluAsp: 0.0 ± 0.0
8.091GluGlu: 8.091 ± 0.812
3.236GluPhe: 3.236 ± 2.137
4.854GluGly: 4.854 ± 1.325
0.0GluHis: 0.0 ± 0.0
3.236GluIle: 3.236 ± 2.137
4.854GluLys: 4.854 ± 3.205
3.236GluLeu: 3.236 ± 0.128
4.854GluMet: 4.854 ± 2.679
1.618GluAsn: 1.618 ± 1.068
0.0GluPro: 0.0 ± 0.0
6.472GluGln: 6.472 ± 0.257
1.618GluArg: 1.618 ± 1.068
1.618GluSer: 1.618 ± 1.068
4.854GluThr: 4.854 ± 3.205
6.472GluVal: 6.472 ± 4.273
3.236GluTrp: 3.236 ± 2.137
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.0PheCys: 0.0 ± 0.0
1.618PheAsp: 1.618 ± 1.197
6.472PheGlu: 6.472 ± 0.257
0.0PhePhe: 0.0 ± 0.0
1.618PheGly: 1.618 ± 1.197
0.0PheHis: 0.0 ± 0.0
1.618PheIle: 1.618 ± 1.197
3.236PheLys: 3.236 ± 0.128
3.236PheLeu: 3.236 ± 0.128
1.618PheMet: 1.618 ± 1.197
1.618PheAsn: 1.618 ± 1.197
0.0PhePro: 0.0 ± 0.0
1.618PheGln: 1.618 ± 1.068
1.618PheArg: 1.618 ± 1.068
1.618PheSer: 1.618 ± 1.197
3.236PheThr: 3.236 ± 0.128
1.618PheVal: 1.618 ± 1.068
0.0PheTrp: 0.0 ± 0.0
3.236PheTyr: 3.236 ± 0.128
0.0PheXaa: 0.0 ± 0.0
Gly
1.618GlyAla: 1.618 ± 1.068
1.618GlyCys: 1.618 ± 1.068
6.472GlyAsp: 6.472 ± 0.257
9.709GlyGlu: 9.709 ± 6.41
1.618GlyPhe: 1.618 ± 1.068
8.091GlyGly: 8.091 ± 0.812
0.0GlyHis: 0.0 ± 0.0
3.236GlyIle: 3.236 ± 2.393
8.091GlyLys: 8.091 ± 3.718
4.854GlyLeu: 4.854 ± 1.325
1.618GlyMet: 1.618 ± 0.764
1.618GlyAsn: 1.618 ± 1.068
1.618GlyPro: 1.618 ± 1.197
1.618GlyGln: 1.618 ± 1.068
3.236GlyArg: 3.236 ± 2.137
0.0GlySer: 0.0 ± 0.0
11.327GlyThr: 11.327 ± 0.684
3.236GlyVal: 3.236 ± 2.137
1.618GlyTrp: 1.618 ± 1.068
6.472GlyTyr: 6.472 ± 2.008
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
3.236HisCys: 3.236 ± 2.137
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
1.618HisGly: 1.618 ± 1.068
0.0HisHis: 0.0 ± 0.0
3.236HisIle: 3.236 ± 0.128
1.618HisLys: 1.618 ± 1.068
3.236HisLeu: 3.236 ± 0.128
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
3.236HisGln: 3.236 ± 0.128
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
1.618HisThr: 1.618 ± 1.197
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
3.236HisTyr: 3.236 ± 0.128
0.0HisXaa: 0.0 ± 0.0
Ile
4.854IleAla: 4.854 ± 1.325
1.618IleCys: 1.618 ± 1.068
6.472IleAsp: 6.472 ± 2.008
1.618IleGlu: 1.618 ± 1.068
1.618IlePhe: 1.618 ± 1.197
4.854IleGly: 4.854 ± 1.325
0.0IleHis: 0.0 ± 0.0
6.472IleIle: 6.472 ± 2.008
4.854IleLys: 4.854 ± 3.205
0.0IleLeu: 0.0 ± 0.0
1.618IleMet: 1.618 ± 1.197
6.472IleAsn: 6.472 ± 2.522
1.618IlePro: 1.618 ± 1.197
0.0IleGln: 0.0 ± 0.0
4.854IleArg: 4.854 ± 1.325
6.472IleSer: 6.472 ± 0.257
1.618IleThr: 1.618 ± 1.068
0.0IleVal: 0.0 ± 0.0
0.0IleTrp: 0.0 ± 0.0
3.236IleTyr: 3.236 ± 2.137
0.0IleXaa: 0.0 ± 0.0
Lys
6.472LysAla: 6.472 ± 0.257
0.0LysCys: 0.0 ± 0.0
4.854LysAsp: 4.854 ± 3.205
0.0LysGlu: 0.0 ± 0.0
3.236LysPhe: 3.236 ± 2.393
6.472LysGly: 6.472 ± 2.008
1.618LysHis: 1.618 ± 1.068
4.854LysIle: 4.854 ± 0.94
12.945LysLys: 12.945 ± 0.513
3.236LysLeu: 3.236 ± 0.128
1.618LysMet: 1.618 ± 1.197
1.618LysAsn: 1.618 ± 1.197
3.236LysPro: 3.236 ± 0.128
3.236LysGln: 3.236 ± 0.128
8.091LysArg: 8.091 ± 1.453
3.236LysSer: 3.236 ± 0.128
6.472LysThr: 6.472 ± 2.522
6.472LysVal: 6.472 ± 0.257
3.236LysTrp: 3.236 ± 2.137
3.236LysTyr: 3.236 ± 0.128
0.0LysXaa: 0.0 ± 0.0
Leu
6.472LeuAla: 6.472 ± 0.257
0.0LeuCys: 0.0 ± 0.0
1.618LeuAsp: 1.618 ± 1.197
3.236LeuGlu: 3.236 ± 2.137
1.618LeuPhe: 1.618 ± 1.197
1.618LeuGly: 1.618 ± 1.068
0.0LeuHis: 0.0 ± 0.0
3.236LeuIle: 3.236 ± 0.128
3.236LeuLys: 3.236 ± 0.128
3.236LeuLeu: 3.236 ± 2.137
0.0LeuMet: 0.0 ± 0.0
3.236LeuAsn: 3.236 ± 0.128
4.854LeuPro: 4.854 ± 1.325
3.236LeuGln: 3.236 ± 0.128
6.472LeuArg: 6.472 ± 0.257
3.236LeuSer: 3.236 ± 0.128
3.236LeuThr: 3.236 ± 0.128
4.854LeuVal: 4.854 ± 3.59
1.618LeuTrp: 1.618 ± 1.068
0.0LeuTyr: 0.0 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
1.618MetAla: 1.618 ± 1.197
1.618MetCys: 1.618 ± 1.068
0.0MetAsp: 0.0 ± 0.0
1.618MetGlu: 1.618 ± 1.197
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.618MetIle: 1.618 ± 1.197
4.854MetLys: 4.854 ± 0.94
1.618MetLeu: 1.618 ± 1.197
1.618MetMet: 1.618 ± 1.197
0.0MetAsn: 0.0 ± 0.0
1.618MetPro: 1.618 ± 1.068
0.0MetGln: 0.0 ± 0.0
1.618MetArg: 1.618 ± 1.068
0.0MetSer: 0.0 ± 0.0
4.854MetThr: 4.854 ± 3.205
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
3.236MetTyr: 3.236 ± 2.393
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
4.854AsnGlu: 4.854 ± 0.94
1.618AsnPhe: 1.618 ± 1.197
0.0AsnGly: 0.0 ± 0.0
1.618AsnHis: 1.618 ± 1.068
3.236AsnIle: 3.236 ± 2.393
1.618AsnLys: 1.618 ± 1.068
1.618AsnLeu: 1.618 ± 1.068
1.618AsnMet: 1.618 ± 1.197
4.854AsnAsn: 4.854 ± 1.325
3.236AsnPro: 3.236 ± 2.393
6.472AsnGln: 6.472 ± 2.522
3.236AsnArg: 3.236 ± 2.393
1.618AsnSer: 1.618 ± 1.197
0.0AsnThr: 0.0 ± 0.0
3.236AsnVal: 3.236 ± 2.393
0.0AsnTrp: 0.0 ± 0.0
1.618AsnTyr: 1.618 ± 1.068
0.0AsnXaa: 0.0 ± 0.0
Pro
6.472ProAla: 6.472 ± 2.522
0.0ProCys: 0.0 ± 0.0
4.854ProAsp: 4.854 ± 3.205
4.854ProGlu: 4.854 ± 0.94
4.854ProPhe: 4.854 ± 1.325
1.618ProGly: 1.618 ± 1.197
3.236ProHis: 3.236 ± 2.137
0.0ProIle: 0.0 ± 0.0
4.854ProLys: 4.854 ± 3.59
0.0ProLeu: 0.0 ± 0.0
4.854ProMet: 4.854 ± 1.325
0.0ProAsn: 0.0 ± 0.0
9.709ProPro: 9.709 ± 4.145
1.618ProGln: 1.618 ± 1.197
3.236ProArg: 3.236 ± 0.128
3.236ProSer: 3.236 ± 2.393
6.472ProThr: 6.472 ± 4.786
4.854ProVal: 4.854 ± 0.94
1.618ProTrp: 1.618 ± 1.197
3.236ProTyr: 3.236 ± 0.128
0.0ProXaa: 0.0 ± 0.0
Gln
1.618GlnAla: 1.618 ± 1.068
1.618GlnCys: 1.618 ± 1.068
4.854GlnAsp: 4.854 ± 0.94
0.0GlnGlu: 0.0 ± 0.0
0.0GlnPhe: 0.0 ± 0.0
3.236GlnGly: 3.236 ± 0.128
1.618GlnHis: 1.618 ± 1.197
8.091GlnIle: 8.091 ± 1.453
3.236GlnLys: 3.236 ± 2.393
3.236GlnLeu: 3.236 ± 2.137
1.618GlnMet: 1.618 ± 1.068
1.618GlnAsn: 1.618 ± 1.197
3.236GlnPro: 3.236 ± 0.128
4.854GlnGln: 4.854 ± 1.325
4.854GlnArg: 4.854 ± 3.59
0.0GlnSer: 0.0 ± 0.0
1.618GlnThr: 1.618 ± 1.197
1.618GlnVal: 1.618 ± 1.197
0.0GlnTrp: 0.0 ± 0.0
1.618GlnTyr: 1.618 ± 1.068
0.0GlnXaa: 0.0 ± 0.0
Arg
1.618ArgAla: 1.618 ± 1.068
1.618ArgCys: 1.618 ± 1.068
0.0ArgAsp: 0.0 ± 0.0
0.0ArgGlu: 0.0 ± 0.0
0.0ArgPhe: 0.0 ± 0.0
1.618ArgGly: 1.618 ± 1.068
3.236ArgHis: 3.236 ± 0.128
3.236ArgIle: 3.236 ± 0.128
9.709ArgLys: 9.709 ± 1.88
1.618ArgLeu: 1.618 ± 1.197
0.0ArgMet: 0.0 ± 0.0
3.236ArgAsn: 3.236 ± 2.393
8.091ArgPro: 8.091 ± 3.718
6.472ArgGln: 6.472 ± 2.008
6.472ArgArg: 6.472 ± 2.522
3.236ArgSer: 3.236 ± 2.393
6.472ArgThr: 6.472 ± 0.257
1.618ArgVal: 1.618 ± 1.197
1.618ArgTrp: 1.618 ± 1.197
1.618ArgTyr: 1.618 ± 1.197
0.0ArgXaa: 0.0 ± 0.0
Ser
3.236SerAla: 3.236 ± 0.128
3.236SerCys: 3.236 ± 0.128
0.0SerAsp: 0.0 ± 0.0
3.236SerGlu: 3.236 ± 0.128
1.618SerPhe: 1.618 ± 1.197
3.236SerGly: 3.236 ± 2.137
1.618SerHis: 1.618 ± 1.068
0.0SerIle: 0.0 ± 0.0
3.236SerLys: 3.236 ± 0.128
3.236SerLeu: 3.236 ± 0.128
0.0SerMet: 0.0 ± 0.0
3.236SerAsn: 3.236 ± 0.128
8.091SerPro: 8.091 ± 3.718
1.618SerGln: 1.618 ± 1.197
1.618SerArg: 1.618 ± 1.197
0.0SerSer: 0.0 ± 0.0
3.236SerThr: 3.236 ± 0.128
1.618SerVal: 1.618 ± 1.197
1.618SerTrp: 1.618 ± 1.068
1.618SerTyr: 1.618 ± 1.197
0.0SerXaa: 0.0 ± 0.0
Thr
6.472ThrAla: 6.472 ± 2.522
1.618ThrCys: 1.618 ± 1.068
4.854ThrAsp: 4.854 ± 1.325
3.236ThrGlu: 3.236 ± 2.137
1.618ThrPhe: 1.618 ± 1.197
6.472ThrGly: 6.472 ± 2.522
1.618ThrHis: 1.618 ± 1.068
1.618ThrIle: 1.618 ± 1.068
1.618ThrLys: 1.618 ± 1.197
6.472ThrLeu: 6.472 ± 2.008
0.0ThrMet: 0.0 ± 0.0
3.236ThrAsn: 3.236 ± 2.393
9.709ThrPro: 9.709 ± 0.385
4.854ThrGln: 4.854 ± 1.325
6.472ThrArg: 6.472 ± 0.257
8.091ThrSer: 8.091 ± 3.718
11.327ThrThr: 11.327 ± 3.846
3.236ThrVal: 3.236 ± 2.137
0.0ThrTrp: 0.0 ± 0.0
3.236ThrTyr: 3.236 ± 2.137
0.0ThrXaa: 0.0 ± 0.0
Val
3.236ValAla: 3.236 ± 0.128
0.0ValCys: 0.0 ± 0.0
0.0ValAsp: 0.0 ± 0.0
3.236ValGlu: 3.236 ± 2.137
1.618ValPhe: 1.618 ± 1.068
3.236ValGly: 3.236 ± 2.137
1.618ValHis: 1.618 ± 1.197
4.854ValIle: 4.854 ± 3.205
3.236ValLys: 3.236 ± 0.128
4.854ValLeu: 4.854 ± 3.59
0.0ValMet: 0.0 ± 0.0
4.854ValAsn: 4.854 ± 1.325
0.0ValPro: 0.0 ± 0.0
1.618ValGln: 1.618 ± 1.197
1.618ValArg: 1.618 ± 1.197
1.618ValSer: 1.618 ± 1.068
3.236ValThr: 3.236 ± 2.393
3.236ValVal: 3.236 ± 2.393
3.236ValTrp: 3.236 ± 2.137
3.236ValTyr: 3.236 ± 2.137
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
1.618TrpCys: 1.618 ± 1.068
0.0TrpAsp: 0.0 ± 0.0
1.618TrpGlu: 1.618 ± 1.197
1.618TrpPhe: 1.618 ± 1.068
4.854TrpGly: 4.854 ± 3.205
1.618TrpHis: 1.618 ± 1.197
3.236TrpIle: 3.236 ± 2.137
1.618TrpLys: 1.618 ± 1.197
1.618TrpLeu: 1.618 ± 1.068
0.0TrpMet: 0.0 ± 0.0
1.618TrpAsn: 1.618 ± 1.068
1.618TrpPro: 1.618 ± 1.068
0.0TrpGln: 0.0 ± 0.0
1.618TrpArg: 1.618 ± 1.068
1.618TrpSer: 1.618 ± 1.197
1.618TrpThr: 1.618 ± 1.068
0.0TrpVal: 0.0 ± 0.0
1.618TrpTrp: 1.618 ± 1.068
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.618TyrAla: 1.618 ± 1.197
1.618TyrCys: 1.618 ± 1.068
0.0TyrAsp: 0.0 ± 0.0
1.618TyrGlu: 1.618 ± 1.197
1.618TyrPhe: 1.618 ± 1.068
6.472TyrGly: 6.472 ± 2.008
1.618TyrHis: 1.618 ± 1.068
1.618TyrIle: 1.618 ± 1.197
1.618TyrLys: 1.618 ± 1.197
1.618TyrLeu: 1.618 ± 1.197
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
4.854TyrPro: 4.854 ± 3.205
1.618TyrGln: 1.618 ± 1.197
1.618TyrArg: 1.618 ± 1.068
4.854TyrSer: 4.854 ± 3.205
4.854TyrThr: 4.854 ± 1.325
1.618TyrVal: 1.618 ± 1.068
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (619 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski