Amino acid dipepetide frequency for Terrapene carolina triunguis (Three-toed box turtle)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.073AlaAla: 6.073 ± 0.032	1.385AlaCys: 1.385 ± 0.011	2.953AlaAsp: 2.953 ± 0.013	4.607AlaGlu: 4.607 ± 0.022	2.472AlaPhe: 2.472 ± 0.012	4.395AlaGly: 4.395 ± 0.021	1.439AlaHis: 1.439 ± 0.01	2.992AlaIle: 2.992 ± 0.014	3.527AlaLys: 3.527 ± 0.018	6.678AlaLeu: 6.678 ± 0.026	1.51AlaMet: 1.51 ± 0.01	2.199AlaAsn: 2.199 ± 0.012	3.336AlaPro: 3.336 ± 0.019	2.933AlaGln: 2.933 ± 0.018	3.197AlaArg: 3.197 ± 0.014	5.227AlaSer: 5.227 ± 0.02	3.383AlaThr: 3.383 ± 0.016	4.683AlaVal: 4.683 ± 0.016	0.751AlaTrp: 0.751 ± 0.007	1.548AlaTyr: 1.548 ± 0.01	0.002AlaXaa: 0.002 ± 0.0
Cys	1.291CysAla: 1.291 ± 0.012	0.673CysCys: 0.673 ± 0.009	1.104CysAsp: 1.104 ± 0.014	1.368CysGlu: 1.368 ± 0.016	0.968CysPhe: 0.968 ± 0.007	1.672CysGly: 1.672 ± 0.02	0.676CysHis: 0.676 ± 0.008	1.183CysIle: 1.183 ± 0.013	1.301CysLys: 1.301 ± 0.012	2.319CysLeu: 2.319 ± 0.015	0.488CysMet: 0.488 ± 0.005	0.916CysAsn: 0.916 ± 0.009	1.393CysPro: 1.393 ± 0.015	1.152CysGln: 1.152 ± 0.016	1.287CysArg: 1.287 ± 0.011	2.127CysSer: 2.127 ± 0.019	1.252CysThr: 1.252 ± 0.012	1.38CysVal: 1.38 ± 0.012	0.322CysTrp: 0.322 ± 0.005	0.665CysTyr: 0.665 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	2.797AspAla: 2.797 ± 0.012	1.174AspCys: 1.174 ± 0.012	2.642AspAsp: 2.642 ± 0.017	3.495AspGlu: 3.495 ± 0.018	2.167AspPhe: 2.167 ± 0.012	3.31AspGly: 3.31 ± 0.021	1.136AspHis: 1.136 ± 0.008	2.849AspIle: 2.849 ± 0.015	2.649AspLys: 2.649 ± 0.014	4.961AspLeu: 4.961 ± 0.021	1.169AspMet: 1.169 ± 0.009	1.859AspAsn: 1.859 ± 0.013	2.735AspPro: 2.735 ± 0.014	1.875AspGln: 1.875 ± 0.011	2.382AspArg: 2.382 ± 0.013	4.088AspSer: 4.088 ± 0.017	2.494AspThr: 2.494 ± 0.013	3.089AspVal: 3.089 ± 0.017	0.667AspTrp: 0.667 ± 0.007	1.577AspTyr: 1.577 ± 0.01	0.0AspXaa: 0.0 ± 0.0
Glu	4.617GluAla: 4.617 ± 0.023	1.455GluCys: 1.455 ± 0.022	4.228GluAsp: 4.228 ± 0.019	7.402GluGlu: 7.402 ± 0.039	2.138GluPhe: 2.138 ± 0.011	4.02GluGly: 4.02 ± 0.016	1.523GluHis: 1.523 ± 0.01	3.531GluIle: 3.531 ± 0.015	5.313GluLys: 5.313 ± 0.026	6.395GluLeu: 6.395 ± 0.032	1.774GluMet: 1.774 ± 0.01	3.346GluAsn: 3.346 ± 0.016	2.749GluPro: 2.749 ± 0.016	3.188GluGln: 3.188 ± 0.017	4.037GluArg: 4.037 ± 0.023	4.468GluSer: 4.468 ± 0.021	3.593GluThr: 3.593 ± 0.015	4.097GluVal: 4.097 ± 0.018	0.727GluTrp: 0.727 ± 0.008	1.73GluTyr: 1.73 ± 0.012	0.001GluXaa: 0.001 ± 0.0
Phe	2.069PheAla: 2.069 ± 0.011	1.009PheCys: 1.009 ± 0.008	1.76PheAsp: 1.76 ± 0.013	2.023PheGlu: 2.023 ± 0.012	1.708PhePhe: 1.708 ± 0.012	2.171PheGly: 2.171 ± 0.013	1.057PheHis: 1.057 ± 0.008	2.051PheIle: 2.051 ± 0.015	1.954PheLys: 1.954 ± 0.011	4.22PheLeu: 4.22 ± 0.021	0.792PheMet: 0.792 ± 0.006	1.513PheAsn: 1.513 ± 0.01	1.997PhePro: 1.997 ± 0.011	1.84PheGln: 1.84 ± 0.01	1.873PheArg: 1.873 ± 0.011	3.416PheSer: 3.416 ± 0.017	2.252PheThr: 2.252 ± 0.014	2.218PheVal: 2.218 ± 0.013	0.496PheTrp: 0.496 ± 0.006	1.27PheTyr: 1.27 ± 0.009	0.0PheXaa: 0.0 ± 0.0
Gly	4.003GlyAla: 4.003 ± 0.023	1.302GlyCys: 1.302 ± 0.011	3.007GlyAsp: 3.007 ± 0.015	3.983GlyGlu: 3.983 ± 0.021	2.401GlyPhe: 2.401 ± 0.015	4.553GlyGly: 4.553 ± 0.027	1.56GlyHis: 1.56 ± 0.012	2.975GlyIle: 2.975 ± 0.015	3.986GlyLys: 3.986 ± 0.018	5.393GlyLeu: 5.393 ± 0.021	1.363GlyMet: 1.363 ± 0.01	2.59GlyAsn: 2.59 ± 0.015	3.111GlyPro: 3.111 ± 0.027	2.675GlyGln: 2.675 ± 0.013	3.531GlyArg: 3.531 ± 0.019	5.438GlySer: 5.438 ± 0.025	3.536GlyThr: 3.536 ± 0.019	3.451GlyVal: 3.451 ± 0.014	0.847GlyTrp: 0.847 ± 0.008	1.861GlyTyr: 1.861 ± 0.015	0.002GlyXaa: 0.002 ± 0.0
His	1.322HisAla: 1.322 ± 0.009	0.775HisCys: 0.775 ± 0.008	0.92HisAsp: 0.92 ± 0.008	1.319HisGlu: 1.319 ± 0.009	1.076HisPhe: 1.076 ± 0.007	1.518HisGly: 1.518 ± 0.009	0.858HisHis: 0.858 ± 0.009	1.317HisIle: 1.317 ± 0.009	1.352HisLys: 1.352 ± 0.01	2.841HisLeu: 2.841 ± 0.016	0.577HisMet: 0.577 ± 0.006	0.989HisAsn: 0.989 ± 0.007	1.57HisPro: 1.57 ± 0.011	1.322HisGln: 1.322 ± 0.012	1.507HisArg: 1.507 ± 0.011	2.263HisSer: 2.263 ± 0.013	1.464HisThr: 1.464 ± 0.013	1.501HisVal: 1.501 ± 0.008	0.364HisTrp: 0.364 ± 0.004	0.87HisTyr: 0.87 ± 0.008	0.001HisXaa: 0.001 ± 0.0
Ile	2.913IleAla: 2.913 ± 0.015	1.222IleCys: 1.222 ± 0.011	2.342IleAsp: 2.342 ± 0.015	2.81IleGlu: 2.81 ± 0.015	2.066IlePhe: 2.066 ± 0.014	2.458IleGly: 2.458 ± 0.013	1.411IleHis: 1.411 ± 0.012	2.683IleIle: 2.683 ± 0.015	2.953IleLys: 2.953 ± 0.016	4.965IleLeu: 4.965 ± 0.023	1.065IleMet: 1.065 ± 0.008	2.166IleAsn: 2.166 ± 0.011	2.797IlePro: 2.797 ± 0.015	2.511IleGln: 2.511 ± 0.013	2.523IleArg: 2.523 ± 0.012	4.172IleSer: 4.172 ± 0.019	2.925IleThr: 2.925 ± 0.014	2.842IleVal: 2.842 ± 0.017	0.563IleTrp: 0.563 ± 0.007	1.558IleTyr: 1.558 ± 0.01	0.0IleXaa: 0.0 ± 0.0
Lys	3.847LysAla: 3.847 ± 0.019	1.284LysCys: 1.284 ± 0.013	3.26LysAsp: 3.26 ± 0.016	5.309LysGlu: 5.309 ± 0.028	1.807LysPhe: 1.807 ± 0.012	3.312LysGly: 3.312 ± 0.019	1.531LysHis: 1.531 ± 0.011	3.005LysIle: 3.005 ± 0.016	4.688LysLys: 4.688 ± 0.026	5.491LysLeu: 5.491 ± 0.025	1.53LysMet: 1.53 ± 0.011	2.661LysAsn: 2.661 ± 0.013	2.944LysPro: 2.944 ± 0.018	2.855LysGln: 2.855 ± 0.016	3.363LysArg: 3.363 ± 0.014	4.15LysSer: 4.15 ± 0.019	3.216LysThr: 3.216 ± 0.014	3.649LysVal: 3.649 ± 0.017	0.679LysTrp: 0.679 ± 0.008	1.735LysTyr: 1.735 ± 0.012	0.001LysXaa: 0.001 ± 0.0
Leu	6.403LeuAla: 6.403 ± 0.029	2.307LeuCys: 2.307 ± 0.017	4.76LeuAsp: 4.76 ± 0.019	6.999LeuGlu: 6.999 ± 0.035	3.592LeuPhe: 3.592 ± 0.02	5.452LeuGly: 5.452 ± 0.02	2.754LeuHis: 2.754 ± 0.015	4.339LeuIle: 4.339 ± 0.02	6.201LeuLys: 6.201 ± 0.026	10.535LeuLeu: 10.535 ± 0.045	2.078LeuMet: 2.078 ± 0.011	3.876LeuAsn: 3.876 ± 0.016	5.565LeuPro: 5.565 ± 0.021	5.749LeuGln: 5.749 ± 0.023	5.432LeuArg: 5.432 ± 0.022	8.004LeuSer: 8.004 ± 0.03	5.097LeuThr: 5.097 ± 0.018	5.461LeuVal: 5.461 ± 0.02	1.121LeuTrp: 1.121 ± 0.009	2.785LeuTyr: 2.785 ± 0.017	0.001LeuXaa: 0.001 ± 0.0
Met	1.772MetAla: 1.772 ± 0.01	0.449MetCys: 0.449 ± 0.006	1.301MetAsp: 1.301 ± 0.008	1.911MetGlu: 1.911 ± 0.011	0.797MetPhe: 0.797 ± 0.007	1.302MetGly: 1.302 ± 0.01	0.508MetHis: 0.508 ± 0.007	0.951MetIle: 0.951 ± 0.009	1.529MetLys: 1.529 ± 0.01	2.114MetLeu: 2.114 ± 0.012	0.583MetMet: 0.583 ± 0.006	0.974MetAsn: 0.974 ± 0.007	1.074MetPro: 1.074 ± 0.011	1.03MetGln: 1.03 ± 0.009	1.057MetArg: 1.057 ± 0.008	1.612MetSer: 1.612 ± 0.009	1.117MetThr: 1.117 ± 0.007	1.475MetVal: 1.475 ± 0.009	0.245MetTrp: 0.245 ± 0.004	0.679MetTyr: 0.679 ± 0.006	0.0MetXaa: 0.0 ± 0.0
Asn	2.272AsnAla: 2.272 ± 0.011	0.992AsnCys: 0.992 ± 0.01	1.688AsnAsp: 1.688 ± 0.011	2.54AsnGlu: 2.54 ± 0.014	1.581AsnPhe: 1.581 ± 0.011	2.717AsnGly: 2.717 ± 0.021	0.997AsnHis: 0.997 ± 0.007	2.466AsnIle: 2.466 ± 0.012	2.487AsnLys: 2.487 ± 0.015	4.023AsnLeu: 4.023 ± 0.019	0.998AsnMet: 0.998 ± 0.008	1.779AsnAsn: 1.779 ± 0.012	2.302AsnPro: 2.302 ± 0.014	1.771AsnGln: 1.771 ± 0.011	1.99AsnArg: 1.99 ± 0.012	3.411AsnSer: 3.411 ± 0.017	2.208AsnThr: 2.208 ± 0.014	2.471AsnVal: 2.471 ± 0.013	0.487AsnTrp: 0.487 ± 0.006	1.247AsnTyr: 1.247 ± 0.01	0.0AsnXaa: 0.0 ± 0.0
Pro	4.116ProAla: 4.116 ± 0.022	1.161ProCys: 1.161 ± 0.015	2.646ProAsp: 2.646 ± 0.015	3.86ProGlu: 3.86 ± 0.017	1.953ProPhe: 1.953 ± 0.013	4.146ProGly: 4.146 ± 0.032	1.39ProHis: 1.39 ± 0.01	2.051ProIle: 2.051 ± 0.012	2.688ProLys: 2.688 ± 0.019	4.928ProLeu: 4.928 ± 0.019	1.019ProMet: 1.019 ± 0.008	1.905ProAsn: 1.905 ± 0.012	4.868ProPro: 4.868 ± 0.04	2.483ProGln: 2.483 ± 0.016	2.759ProArg: 2.759 ± 0.015	5.087ProSer: 5.087 ± 0.028	2.763ProThr: 2.763 ± 0.015	3.673ProVal: 3.673 ± 0.017	0.634ProTrp: 0.634 ± 0.007	1.488ProTyr: 1.488 ± 0.013	0.002ProXaa: 0.002 ± 0.0
Gln	3.184GlnAla: 3.184 ± 0.018	1.06GlnCys: 1.06 ± 0.013	2.25GlnAsp: 2.25 ± 0.012	3.719GlnGlu: 3.719 ± 0.019	1.469GlnPhe: 1.469 ± 0.009	2.671GlnGly: 2.671 ± 0.014	1.354GlnHis: 1.354 ± 0.01	2.246GlnIle: 2.246 ± 0.012	2.977GlnLys: 2.977 ± 0.016	4.794GlnLeu: 4.794 ± 0.021	1.107GlnMet: 1.107 ± 0.008	2.072GlnAsn: 2.072 ± 0.011	2.502GlnPro: 2.502 ± 0.018	3.124GlnGln: 3.124 ± 0.027	2.865GlnArg: 2.865 ± 0.017	3.28GlnSer: 3.28 ± 0.018	2.437GlnThr: 2.437 ± 0.013	2.782GlnVal: 2.782 ± 0.015	0.571GlnTrp: 0.571 ± 0.006	1.294GlnTyr: 1.294 ± 0.01	0.001GlnXaa: 0.001 ± 0.0
Arg	3.358ArgAla: 3.358 ± 0.015	1.268ArgCys: 1.268 ± 0.016	2.606ArgAsp: 2.606 ± 0.014	3.794ArgGlu: 3.794 ± 0.021	1.906ArgPhe: 1.906 ± 0.012	3.265ArgGly: 3.265 ± 0.021	1.45ArgHis: 1.45 ± 0.009	2.611ArgIle: 2.611 ± 0.014	3.583ArgLys: 3.583 ± 0.017	5.092ArgLeu: 5.092 ± 0.022	1.213ArgMet: 1.213 ± 0.009	2.205ArgAsn: 2.205 ± 0.011	2.73ArgPro: 2.73 ± 0.017	2.56ArgGln: 2.56 ± 0.014	3.785ArgArg: 3.785 ± 0.021	4.082ArgSer: 4.082 ± 0.022	2.779ArgThr: 2.779 ± 0.016	3.002ArgVal: 3.002 ± 0.015	0.703ArgTrp: 0.703 ± 0.007	1.583ArgTyr: 1.583 ± 0.01	0.001ArgXaa: 0.001 ± 0.0
Ser	5.192SerAla: 5.192 ± 0.024	1.936SerCys: 1.936 ± 0.017	3.978SerAsp: 3.978 ± 0.019	5.117SerGlu: 5.117 ± 0.021	3.181SerPhe: 3.181 ± 0.016	5.207SerGly: 5.207 ± 0.021	2.13SerHis: 2.13 ± 0.013	3.62SerIle: 3.62 ± 0.015	4.247SerLys: 4.247 ± 0.019	8.174SerLeu: 8.174 ± 0.028	1.686SerMet: 1.686 ± 0.01	3.018SerAsn: 3.018 ± 0.015	5.487SerPro: 5.487 ± 0.027	3.77SerGln: 3.77 ± 0.018	4.161SerArg: 4.161 ± 0.021	8.995SerSer: 8.995 ± 0.051	4.496SerThr: 4.496 ± 0.02	5.009SerVal: 5.009 ± 0.02	1.05SerTrp: 1.05 ± 0.009	2.251SerTyr: 2.251 ± 0.013	0.001SerXaa: 0.001 ± 0.0
Thr	3.739ThrAla: 3.739 ± 0.015	1.447ThrCys: 1.447 ± 0.021	2.694ThrAsp: 2.694 ± 0.014	3.656ThrGlu: 3.656 ± 0.016	2.158ThrPhe: 2.158 ± 0.012	3.599ThrGly: 3.599 ± 0.018	1.295ThrHis: 1.295 ± 0.011	2.692ThrIle: 2.692 ± 0.015	2.785ThrLys: 2.785 ± 0.014	5.312ThrLeu: 5.312 ± 0.019	1.141ThrMet: 1.141 ± 0.008	1.959ThrAsn: 1.959 ± 0.011	3.27ThrPro: 3.27 ± 0.021	2.24ThrGln: 2.24 ± 0.013	2.375ThrArg: 2.375 ± 0.012	4.58ThrSer: 4.58 ± 0.023	2.941ThrThr: 2.941 ± 0.019	3.975ThrVal: 3.975 ± 0.018	0.703ThrTrp: 0.703 ± 0.007	1.541ThrTyr: 1.541 ± 0.01	0.001ThrXaa: 0.001 ± 0.0
Val	4.019ValAla: 4.019 ± 0.016	1.588ValCys: 1.588 ± 0.013	2.904ValAsp: 2.904 ± 0.016	3.863ValGlu: 3.863 ± 0.015	2.452ValPhe: 2.452 ± 0.014	3.257ValGly: 3.257 ± 0.015	1.558ValHis: 1.558 ± 0.01	3.126ValIle: 3.126 ± 0.015	3.605ValLys: 3.605 ± 0.018	6.175ValLeu: 6.175 ± 0.024	1.393ValMet: 1.393 ± 0.01	2.554ValAsn: 2.554 ± 0.015	3.356ValPro: 3.356 ± 0.013	2.816ValGln: 2.816 ± 0.015	3.043ValArg: 3.043 ± 0.016	5.07ValSer: 5.07 ± 0.019	3.859ValThr: 3.859 ± 0.018	3.926ValVal: 3.926 ± 0.018	0.725ValTrp: 0.725 ± 0.007	1.768ValTyr: 1.768 ± 0.011	0.001ValXaa: 0.001 ± 0.0
Trp	0.782TrpAla: 0.782 ± 0.007	0.264TrpCys: 0.264 ± 0.004	0.668TrpAsp: 0.668 ± 0.007	0.805TrpGlu: 0.805 ± 0.007	0.447TrpPhe: 0.447 ± 0.005	0.804TrpGly: 0.804 ± 0.009	0.31TrpHis: 0.31 ± 0.004	0.641TrpIle: 0.641 ± 0.007	0.828TrpLys: 0.828 ± 0.007	1.271TrpLeu: 1.271 ± 0.01	0.321TrpMet: 0.321 ± 0.004	0.58TrpAsn: 0.58 ± 0.006	0.489TrpPro: 0.489 ± 0.005	0.544TrpGln: 0.544 ± 0.005	0.701TrpArg: 0.701 ± 0.007	0.875TrpSer: 0.875 ± 0.008	0.659TrpThr: 0.659 ± 0.007	0.718TrpVal: 0.718 ± 0.007	0.193TrpTrp: 0.193 ± 0.004	0.361TrpTyr: 0.361 ± 0.006	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.519TyrAla: 1.519 ± 0.011	0.786TyrCys: 0.786 ± 0.008	1.405TyrAsp: 1.405 ± 0.011	1.748TyrGlu: 1.748 ± 0.01	1.351TyrPhe: 1.351 ± 0.01	1.738TyrGly: 1.738 ± 0.013	0.785TyrHis: 0.785 ± 0.007	1.616TyrIle: 1.616 ± 0.01	1.666TyrLys: 1.666 ± 0.012	2.827TyrLeu: 2.827 ± 0.014	0.674TyrMet: 0.674 ± 0.006	1.267TyrAsn: 1.267 ± 0.01	1.342TyrPro: 1.342 ± 0.01	1.32TyrGln: 1.32 ± 0.01	1.707TyrArg: 1.707 ± 0.012	2.36TyrSer: 2.36 ± 0.011	1.633TyrThr: 1.633 ± 0.012	1.653TyrVal: 1.653 ± 0.009	0.412TyrTrp: 0.412 ± 0.007	1.072TyrTyr: 1.072 ± 0.009	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.002XaaGly: 0.002 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.002XaaLeu: 0.002 ± 0.0	0.001XaaMet: 0.001 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.002XaaPro: 0.002 ± 0.0	0.001XaaGln: 0.001 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.081XaaXaa: 0.081 ± 0.014

Statistics based on 31610 proteins (18936447 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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