Amino acid dipepetide frequency for Rosellinia necatrix megabirnavirus 1 (isolate -/Japan/W779/2001) (RnMBV1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
16.238AlaAla: 16.238 ± 1.641
2.998AlaCys: 2.998 ± 1.152
5.996AlaAsp: 5.996 ± 0.892
5.246AlaGlu: 5.246 ± 1.083
2.498AlaPhe: 2.498 ± 0.39
12.491AlaGly: 12.491 ± 0.981
2.498AlaHis: 2.498 ± 0.19
2.998AlaIle: 2.998 ± 0.505
2.998AlaLys: 2.998 ± 1.098
9.243AlaLeu: 9.243 ± 2.901
4.247AlaMet: 4.247 ± 1.178
4.746AlaAsn: 4.746 ± 1.031
4.996AlaPro: 4.996 ± 1.049
4.746AlaGln: 4.746 ± 0.902
6.995AlaArg: 6.995 ± 1.299
3.997AlaSer: 3.997 ± 0.975
7.245AlaThr: 7.245 ± 1.395
9.243AlaVal: 9.243 ± 1.244
1.499AlaTrp: 1.499 ± 0.628
3.747AlaTyr: 3.747 ± 0.785
0.0AlaXaa: 0.0 ± 0.0
Cys
1.499CysAla: 1.499 ± 0.406
0.25CysCys: 0.25 ± 0.328
0.749CysAsp: 0.749 ± 0.346
1.499CysGlu: 1.499 ± 0.406
0.749CysPhe: 0.749 ± 0.342
0.999CysGly: 0.999 ± 0.168
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
2.498CysLeu: 2.498 ± 0.743
0.0CysMet: 0.0 ± 0.0
0.5CysAsn: 0.5 ± 0.418
0.749CysPro: 0.749 ± 0.077
0.25CysGln: 0.25 ± 0.209
0.749CysArg: 0.749 ± 0.343
0.999CysSer: 0.999 ± 0.451
0.999CysThr: 0.999 ± 0.419
0.749CysVal: 0.749 ± 0.37
0.25CysTrp: 0.25 ± 0.194
0.25CysTyr: 0.25 ± 0.194
0.0CysXaa: 0.0 ± 0.0
Asp
7.245AspAla: 7.245 ± 0.769
0.25AspCys: 0.25 ± 0.216
3.248AspAsp: 3.248 ± 0.518
2.248AspGlu: 2.248 ± 0.279
3.997AspPhe: 3.997 ± 1.584
4.497AspGly: 4.497 ± 0.526
0.749AspHis: 0.749 ± 0.353
1.999AspIle: 1.999 ± 0.633
1.749AspLys: 1.749 ± 0.341
6.495AspLeu: 6.495 ± 0.522
2.248AspMet: 2.248 ± 0.512
2.248AspAsn: 2.248 ± 1.315
2.998AspPro: 2.998 ± 0.528
0.749AspGln: 0.749 ± 0.346
3.997AspArg: 3.997 ± 0.821
2.498AspSer: 2.498 ± 0.433
4.497AspThr: 4.497 ± 1.351
3.747AspVal: 3.747 ± 0.923
0.999AspTrp: 0.999 ± 0.564
1.499AspTyr: 1.499 ± 0.492
0.0AspXaa: 0.0 ± 0.0
Glu
7.245GluAla: 7.245 ± 1.333
0.749GluCys: 0.749 ± 0.077
0.5GluAsp: 0.5 ± 0.431
1.999GluGlu: 1.999 ± 0.9
2.998GluPhe: 2.998 ± 0.506
2.998GluGly: 2.998 ± 0.263
1.499GluHis: 1.499 ± 0.639
1.999GluIle: 1.999 ± 0.872
0.999GluLys: 0.999 ± 0.588
5.996GluLeu: 5.996 ± 1.709
1.249GluMet: 1.249 ± 0.787
0.999GluAsn: 0.999 ± 0.247
1.749GluPro: 1.749 ± 0.499
1.249GluGln: 1.249 ± 0.5
4.247GluArg: 4.247 ± 1.088
2.748GluSer: 2.748 ± 0.62
1.749GluThr: 1.749 ± 0.687
2.998GluVal: 2.998 ± 0.681
1.249GluTrp: 1.249 ± 0.355
2.998GluTyr: 2.998 ± 0.782
0.0GluXaa: 0.0 ± 0.0
Phe
3.248PheAla: 3.248 ± 0.688
0.0PheCys: 0.0 ± 0.0
3.747PheAsp: 3.747 ± 1.347
0.749PheGlu: 0.749 ± 0.342
0.999PhePhe: 0.999 ± 0.261
3.997PheGly: 3.997 ± 0.8
0.999PheHis: 0.999 ± 0.862
1.249PheIle: 1.249 ± 0.457
0.749PheLys: 0.749 ± 0.077
2.498PheLeu: 2.498 ± 0.705
0.5PheMet: 0.5 ± 0.431
2.248PheAsn: 2.248 ± 0.786
1.499PhePro: 1.499 ± 0.274
0.999PheGln: 0.999 ± 0.247
1.249PheArg: 1.249 ± 0.23
2.748PheSer: 2.748 ± 0.66
2.998PheThr: 2.998 ± 0.817
4.247PheVal: 4.247 ± 0.305
0.5PheTrp: 0.5 ± 0.431
0.5PheTyr: 0.5 ± 0.243
0.0PheXaa: 0.0 ± 0.0
Gly
8.244GlyAla: 8.244 ± 0.765
1.499GlyCys: 1.499 ± 0.603
4.247GlyAsp: 4.247 ± 1.074
4.996GlyGlu: 4.996 ± 1.072
3.997GlyPhe: 3.997 ± 1.246
9.243GlyGly: 9.243 ± 1.02
1.499GlyHis: 1.499 ± 0.458
3.747GlyIle: 3.747 ± 0.521
1.499GlyLys: 1.499 ± 0.457
9.243GlyLeu: 9.243 ± 1.046
1.749GlyMet: 1.749 ± 0.499
3.497GlyAsn: 3.497 ± 0.968
0.749GlyPro: 0.749 ± 0.37
3.997GlyGln: 3.997 ± 1.392
6.745GlyArg: 6.745 ± 1.252
4.996GlySer: 4.996 ± 1.721
6.995GlyThr: 6.995 ± 0.889
8.244GlyVal: 8.244 ± 1.289
1.249GlyTrp: 1.249 ± 0.23
3.248GlyTyr: 3.248 ± 1.004
0.0GlyXaa: 0.0 ± 0.0
His
2.248HisAla: 2.248 ± 0.726
0.5HisCys: 0.5 ± 0.209
1.749HisAsp: 1.749 ± 0.807
0.749HisGlu: 0.749 ± 0.626
0.25HisPhe: 0.25 ± 0.216
2.248HisGly: 2.248 ± 0.515
0.749HisHis: 0.749 ± 0.077
1.249HisIle: 1.249 ± 0.326
0.0HisLys: 0.0 ± 0.0
0.999HisLeu: 0.999 ± 0.455
0.25HisMet: 0.25 ± 0.216
1.999HisAsn: 1.999 ± 0.428
0.5HisPro: 0.5 ± 0.431
0.5HisGln: 0.5 ± 0.243
1.499HisArg: 1.499 ± 0.795
0.999HisSer: 0.999 ± 0.485
1.249HisThr: 1.249 ± 0.303
1.499HisVal: 1.499 ± 0.154
0.25HisTrp: 0.25 ± 0.209
0.5HisTyr: 0.5 ± 0.365
0.0HisXaa: 0.0 ± 0.0
Ile
3.747IleAla: 3.747 ± 0.725
0.25IleCys: 0.25 ± 0.216
2.998IleAsp: 2.998 ± 1.095
1.499IleGlu: 1.499 ± 0.691
1.249IlePhe: 1.249 ± 0.492
2.748IleGly: 2.748 ± 0.65
0.749IleHis: 0.749 ± 0.077
0.749IleIle: 0.749 ± 0.647
0.999IleLys: 0.999 ± 0.168
3.497IleLeu: 3.497 ± 0.512
0.749IleMet: 0.749 ± 0.647
1.749IleAsn: 1.749 ± 0.93
1.999IlePro: 1.999 ± 0.85
1.499IleGln: 1.499 ± 0.966
2.998IleArg: 2.998 ± 0.977
1.999IleSer: 1.999 ± 0.501
2.748IleThr: 2.748 ± 1.017
3.997IleVal: 3.997 ± 0.851
0.5IleTrp: 0.5 ± 0.176
1.249IleTyr: 1.249 ± 0.303
0.0IleXaa: 0.0 ± 0.0
Lys
1.749LysAla: 1.749 ± 0.295
0.5LysCys: 0.5 ± 0.365
1.499LysAsp: 1.499 ± 0.728
0.999LysGlu: 0.999 ± 0.261
0.999LysPhe: 0.999 ± 0.544
1.999LysGly: 1.999 ± 0.685
0.5LysHis: 0.5 ± 0.418
1.499LysIle: 1.499 ± 0.274
0.749LysLys: 0.749 ± 0.398
2.998LysLeu: 2.998 ± 1.057
0.999LysMet: 0.999 ± 0.485
0.999LysAsn: 0.999 ± 0.485
0.5LysPro: 0.5 ± 0.431
1.249LysGln: 1.249 ± 0.564
2.248LysArg: 2.248 ± 0.855
0.999LysSer: 0.999 ± 0.451
0.999LysThr: 0.999 ± 0.607
2.498LysVal: 2.498 ± 0.673
0.25LysTrp: 0.25 ± 0.194
0.5LysTyr: 0.5 ± 0.388
0.0LysXaa: 0.0 ± 0.0
Leu
11.491LeuAla: 11.491 ± 1.152
1.499LeuCys: 1.499 ± 0.275
5.246LeuAsp: 5.246 ± 0.655
4.746LeuGlu: 4.746 ± 0.915
2.748LeuPhe: 2.748 ± 0.89
7.994LeuGly: 7.994 ± 0.745
2.748LeuHis: 2.748 ± 0.424
2.248LeuIle: 2.248 ± 0.726
3.497LeuLys: 3.497 ± 1.303
8.993LeuLeu: 8.993 ± 1.93
0.5LeuMet: 0.5 ± 0.176
3.747LeuAsn: 3.747 ± 0.909
4.497LeuPro: 4.497 ± 0.821
3.248LeuGln: 3.248 ± 0.497
7.744LeuArg: 7.744 ± 0.71
8.494LeuSer: 8.494 ± 0.864
7.744LeuThr: 7.744 ± 2.361
4.247LeuVal: 4.247 ± 1.462
1.499LeuTrp: 1.499 ± 0.406
2.748LeuTyr: 2.748 ± 1.165
0.0LeuXaa: 0.0 ± 0.0
Met
1.999MetAla: 1.999 ± 0.501
0.25MetCys: 0.25 ± 0.216
1.249MetAsp: 1.249 ± 0.457
2.248MetGlu: 2.248 ± 1.1
0.999MetPhe: 0.999 ± 0.862
2.248MetGly: 2.248 ± 0.266
1.249MetHis: 1.249 ± 0.637
0.25MetIle: 0.25 ± 0.216
0.5MetLys: 0.5 ± 0.418
3.248MetLeu: 3.248 ± 0.497
1.249MetMet: 1.249 ± 0.435
0.999MetAsn: 0.999 ± 0.607
1.999MetPro: 1.999 ± 0.591
0.749MetGln: 0.749 ± 0.346
2.748MetArg: 2.748 ± 0.543
1.499MetSer: 1.499 ± 0.457
0.749MetThr: 0.749 ± 0.077
1.999MetVal: 1.999 ± 0.952
0.25MetTrp: 0.25 ± 0.209
1.249MetTyr: 1.249 ± 0.303
0.0MetXaa: 0.0 ± 0.0
Asn
5.246AsnAla: 5.246 ± 0.886
0.5AsnCys: 0.5 ± 0.418
1.749AsnAsp: 1.749 ± 0.885
1.499AsnGlu: 1.499 ± 0.458
1.749AsnPhe: 1.749 ± 0.873
4.746AsnGly: 4.746 ± 0.84
0.5AsnHis: 0.5 ± 0.388
1.499AsnIle: 1.499 ± 0.458
0.25AsnLys: 0.25 ± 0.216
2.998AsnLeu: 2.998 ± 0.59
2.498AsnMet: 2.498 ± 0.342
1.999AsnAsn: 1.999 ± 0.501
0.999AsnPro: 0.999 ± 0.544
1.499AsnGln: 1.499 ± 0.528
1.999AsnArg: 1.999 ± 0.494
1.999AsnSer: 1.999 ± 0.522
1.749AsnThr: 1.749 ± 0.667
5.246AsnVal: 5.246 ± 0.792
0.749AsnTrp: 0.749 ± 0.398
1.249AsnTyr: 1.249 ± 0.625
0.0AsnXaa: 0.0 ± 0.0
Pro
5.496ProAla: 5.496 ± 0.977
0.0ProCys: 0.0 ± 0.0
1.499ProAsp: 1.499 ± 0.603
1.499ProGlu: 1.499 ± 0.789
0.999ProPhe: 0.999 ± 0.669
3.747ProGly: 3.747 ± 0.534
0.999ProHis: 0.999 ± 0.247
2.998ProIle: 2.998 ± 0.83
0.749ProLys: 0.749 ± 0.647
4.746ProLeu: 4.746 ± 0.772
1.499ProMet: 1.499 ± 0.154
2.498ProAsn: 2.498 ± 0.88
1.999ProPro: 1.999 ± 0.839
0.749ProGln: 0.749 ± 0.077
2.998ProArg: 2.998 ± 0.841
2.748ProSer: 2.748 ± 0.883
2.748ProThr: 2.748 ± 0.689
2.998ProVal: 2.998 ± 0.632
0.0ProTrp: 0.0 ± 0.0
0.25ProTyr: 0.25 ± 0.194
0.0ProXaa: 0.0 ± 0.0
Gln
2.498GlnAla: 2.498 ± 0.739
0.5GlnCys: 0.5 ± 0.243
1.249GlnAsp: 1.249 ± 0.23
1.249GlnGlu: 1.249 ± 0.308
0.749GlnPhe: 0.749 ± 0.409
2.248GlnGly: 2.248 ± 0.345
0.999GlnHis: 0.999 ± 0.247
0.999GlnIle: 0.999 ± 0.352
0.749GlnLys: 0.749 ± 0.398
4.746GlnLeu: 4.746 ± 0.912
0.999GlnMet: 0.999 ± 0.436
0.749GlnAsn: 0.749 ± 0.647
1.749GlnPro: 1.749 ± 0.386
1.249GlnGln: 1.249 ± 0.457
1.999GlnArg: 1.999 ± 0.203
0.999GlnSer: 0.999 ± 0.247
1.749GlnThr: 1.749 ± 0.341
2.248GlnVal: 2.248 ± 0.661
0.25GlnTrp: 0.25 ± 0.216
1.249GlnTyr: 1.249 ± 0.174
0.0GlnXaa: 0.0 ± 0.0
Arg
8.993ArgAla: 8.993 ± 1.277
0.999ArgCys: 0.999 ± 0.52
4.247ArgAsp: 4.247 ± 0.381
3.997ArgGlu: 3.997 ± 1.309
2.748ArgPhe: 2.748 ± 0.626
4.497ArgGly: 4.497 ± 0.731
0.5ArgHis: 0.5 ± 0.418
3.747ArgIle: 3.747 ± 0.402
1.499ArgLys: 1.499 ± 0.483
7.494ArgLeu: 7.494 ± 1.28
1.749ArgMet: 1.749 ± 0.873
4.247ArgAsn: 4.247 ± 0.649
1.999ArgPro: 1.999 ± 0.751
1.749ArgGln: 1.749 ± 0.442
7.245ArgArg: 7.245 ± 0.926
3.997ArgSer: 3.997 ± 0.487
3.248ArgThr: 3.248 ± 0.474
6.745ArgVal: 6.745 ± 1.707
1.499ArgTrp: 1.499 ± 0.154
1.249ArgTyr: 1.249 ± 0.303
0.0ArgXaa: 0.0 ± 0.0
Ser
6.495SerAla: 6.495 ± 0.746
0.999SerCys: 0.999 ± 0.168
4.746SerAsp: 4.746 ± 0.603
3.248SerGlu: 3.248 ± 0.92
2.998SerPhe: 2.998 ± 0.673
6.745SerGly: 6.745 ± 0.837
0.5SerHis: 0.5 ± 0.418
2.498SerIle: 2.498 ± 0.46
3.248SerLys: 3.248 ± 0.461
5.746SerLeu: 5.746 ± 0.657
1.249SerMet: 1.249 ± 0.625
0.999SerAsn: 0.999 ± 0.419
0.749SerPro: 0.749 ± 0.343
1.249SerGln: 1.249 ± 0.5
3.248SerArg: 3.248 ± 1.662
4.497SerSer: 4.497 ± 1.279
3.248SerThr: 3.248 ± 0.474
5.246SerVal: 5.246 ± 1.611
1.249SerTrp: 1.249 ± 0.174
1.749SerTyr: 1.749 ± 0.435
0.0SerXaa: 0.0 ± 0.0
Thr
5.246ThrAla: 5.246 ± 0.777
0.0ThrCys: 0.0 ± 0.0
4.996ThrAsp: 4.996 ± 1.157
2.748ThrGlu: 2.748 ± 0.598
1.749ThrPhe: 1.749 ± 0.667
3.497ThrGly: 3.497 ± 1.295
1.499ThrHis: 1.499 ± 0.483
3.747ThrIle: 3.747 ± 0.407
1.249ThrLys: 1.249 ± 0.457
3.497ThrLeu: 3.497 ± 1.191
1.499ThrMet: 1.499 ± 0.274
1.999ThrAsn: 1.999 ± 1.1
3.997ThrPro: 3.997 ± 1.392
0.25ThrGln: 0.25 ± 0.194
5.496ThrArg: 5.496 ± 1.268
5.746ThrSer: 5.746 ± 0.968
3.497ThrThr: 3.497 ± 1.473
7.245ThrVal: 7.245 ± 0.82
1.249ThrTrp: 1.249 ± 0.457
1.749ThrTyr: 1.749 ± 0.323
0.0ThrXaa: 0.0 ± 0.0
Val
11.991ValAla: 11.991 ± 2.024
0.999ValCys: 0.999 ± 0.419
5.246ValAsp: 5.246 ± 2.004
5.246ValGlu: 5.246 ± 0.746
1.499ValPhe: 1.499 ± 0.314
8.993ValGly: 8.993 ± 2.264
1.249ValHis: 1.249 ± 0.174
2.998ValIle: 2.998 ± 0.663
1.749ValLys: 1.749 ± 0.917
5.746ValLeu: 5.746 ± 0.79
2.498ValMet: 2.498 ± 0.932
2.498ValAsn: 2.498 ± 0.39
5.496ValPro: 5.496 ± 0.545
1.999ValGln: 1.999 ± 0.656
5.496ValArg: 5.496 ± 0.974
4.746ValSer: 4.746 ± 1.407
4.247ValThr: 4.247 ± 0.787
7.494ValVal: 7.494 ± 1.662
0.749ValTrp: 0.749 ± 0.346
2.498ValTyr: 2.498 ± 0.679
0.0ValXaa: 0.0 ± 0.0
Trp
0.999TrpAla: 0.999 ± 0.168
0.25TrpCys: 0.25 ± 0.209
0.999TrpAsp: 0.999 ± 0.352
0.25TrpGlu: 0.25 ± 0.216
0.5TrpPhe: 0.5 ± 0.388
0.749TrpGly: 0.749 ± 0.409
0.0TrpHis: 0.0 ± 0.0
0.5TrpIle: 0.5 ± 0.418
0.0TrpLys: 0.0 ± 0.0
1.999TrpLeu: 1.999 ± 1.402
0.749TrpMet: 0.749 ± 0.409
0.749TrpAsn: 0.749 ± 0.398
0.5TrpPro: 0.5 ± 0.176
0.25TrpGln: 0.25 ± 0.209
0.999TrpArg: 0.999 ± 0.52
1.999TrpSer: 1.999 ± 0.272
0.749TrpThr: 0.749 ± 0.583
0.999TrpVal: 0.999 ± 0.476
0.25TrpTrp: 0.25 ± 0.194
1.499TrpTyr: 1.499 ± 0.406
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.748TyrAla: 2.748 ± 0.946
0.749TyrCys: 0.749 ± 0.37
1.999TyrAsp: 1.999 ± 0.501
1.499TyrGlu: 1.499 ± 0.671
1.249TyrPhe: 1.249 ± 0.466
2.998TyrGly: 2.998 ± 0.673
0.5TyrHis: 0.5 ± 0.365
0.999TyrIle: 0.999 ± 0.247
1.499TyrLys: 1.499 ± 0.818
2.998TyrLeu: 2.998 ± 0.506
0.999TyrMet: 0.999 ± 0.613
1.249TyrAsn: 1.249 ± 0.23
1.499TyrPro: 1.499 ± 0.314
0.999TyrGln: 0.999 ± 0.476
1.749TyrArg: 1.749 ± 0.323
1.999TyrSer: 1.999 ± 0.562
1.749TyrThr: 1.749 ± 0.544
1.749TyrVal: 1.749 ± 0.544
0.5TyrTrp: 0.5 ± 0.418
0.5TyrTyr: 0.5 ± 0.431
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (4004 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski