Amino acid dipepetide frequency for Bean yellow disorder virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.772AlaAla: 1.772 ± 0.486
0.394AlaCys: 0.394 ± 0.412
1.969AlaAsp: 1.969 ± 0.828
1.575AlaGlu: 1.575 ± 0.786
2.166AlaPhe: 2.166 ± 0.47
2.166AlaGly: 2.166 ± 0.848
0.984AlaHis: 0.984 ± 0.365
3.15AlaIle: 3.15 ± 0.862
3.741AlaLys: 3.741 ± 0.505
4.332AlaLeu: 4.332 ± 0.688
0.788AlaMet: 0.788 ± 0.304
2.756AlaAsn: 2.756 ± 0.555
0.984AlaPro: 0.984 ± 0.287
1.378AlaGln: 1.378 ± 0.461
2.756AlaArg: 2.756 ± 0.569
3.15AlaSer: 3.15 ± 1.2
1.181AlaThr: 1.181 ± 0.397
2.166AlaVal: 2.166 ± 0.629
0.0AlaTrp: 0.0 ± 0.0
1.378AlaTyr: 1.378 ± 0.812
0.0AlaXaa: 0.0 ± 0.0
Cys
0.591CysAla: 0.591 ± 0.306
0.197CysCys: 0.197 ± 0.227
1.181CysAsp: 1.181 ± 0.467
0.591CysGlu: 0.591 ± 0.393
1.969CysPhe: 1.969 ± 0.694
0.984CysGly: 0.984 ± 0.368
0.0CysHis: 0.0 ± 0.0
1.181CysIle: 1.181 ± 0.54
0.591CysLys: 0.591 ± 0.257
1.378CysLeu: 1.378 ± 0.385
0.984CysMet: 0.984 ± 0.415
1.969CysAsn: 1.969 ± 0.483
0.197CysPro: 0.197 ± 0.131
0.788CysGln: 0.788 ± 0.352
1.575CysArg: 1.575 ± 0.657
1.969CysSer: 1.969 ± 0.381
0.788CysThr: 0.788 ± 0.261
1.772CysVal: 1.772 ± 0.961
0.394CysTrp: 0.394 ± 0.185
1.772CysTyr: 1.772 ± 0.653
0.0CysXaa: 0.0 ± 0.0
Asp
2.56AspAla: 2.56 ± 0.402
0.984AspCys: 0.984 ± 0.272
2.363AspAsp: 2.363 ± 0.676
5.316AspGlu: 5.316 ± 0.691
5.71AspPhe: 5.71 ± 1.355
3.938AspGly: 3.938 ± 0.661
1.378AspHis: 1.378 ± 0.444
4.135AspIle: 4.135 ± 0.557
4.528AspLys: 4.528 ± 0.819
5.316AspLeu: 5.316 ± 1.306
0.984AspMet: 0.984 ± 0.432
4.332AspAsn: 4.332 ± 1.274
1.969AspPro: 1.969 ± 0.822
0.984AspGln: 0.984 ± 0.429
1.378AspArg: 1.378 ± 0.328
3.347AspSer: 3.347 ± 0.616
2.756AspThr: 2.756 ± 0.817
4.725AspVal: 4.725 ± 1.077
0.394AspTrp: 0.394 ± 0.286
2.56AspTyr: 2.56 ± 0.489
0.0AspXaa: 0.0 ± 0.0
Glu
1.772GluAla: 1.772 ± 0.559
0.788GluCys: 0.788 ± 0.327
3.741GluAsp: 3.741 ± 1.064
3.347GluGlu: 3.347 ± 1.211
3.15GluPhe: 3.15 ± 0.911
3.347GluGly: 3.347 ± 0.681
1.181GluHis: 1.181 ± 0.569
4.922GluIle: 4.922 ± 0.988
4.725GluLys: 4.725 ± 1.352
6.3GluLeu: 6.3 ± 0.714
0.984GluMet: 0.984 ± 0.362
4.725GluAsn: 4.725 ± 1.226
1.378GluPro: 1.378 ± 0.393
0.591GluGln: 0.591 ± 0.286
2.756GluArg: 2.756 ± 0.674
2.953GluSer: 2.953 ± 1.103
3.15GluThr: 3.15 ± 0.445
2.756GluVal: 2.756 ± 0.807
0.591GluTrp: 0.591 ± 0.252
2.756GluTyr: 2.756 ± 0.943
0.0GluXaa: 0.0 ± 0.0
Phe
1.378PheAla: 1.378 ± 0.53
1.575PheCys: 1.575 ± 0.454
3.938PheAsp: 3.938 ± 1.277
5.119PheGlu: 5.119 ± 1.128
1.772PhePhe: 1.772 ± 0.608
2.56PheGly: 2.56 ± 0.575
0.788PheHis: 0.788 ± 0.371
3.938PheIle: 3.938 ± 0.841
4.725PheLys: 4.725 ± 1.662
4.725PheLeu: 4.725 ± 1.112
1.772PheMet: 1.772 ± 0.483
3.544PheAsn: 3.544 ± 1.019
1.378PhePro: 1.378 ± 0.46
1.181PheGln: 1.181 ± 0.574
3.347PheArg: 3.347 ± 0.743
6.104PheSer: 6.104 ± 1.299
3.15PheThr: 3.15 ± 0.673
4.725PheVal: 4.725 ± 0.916
0.394PheTrp: 0.394 ± 0.412
2.56PheTyr: 2.56 ± 0.407
0.0PheXaa: 0.0 ± 0.0
Gly
2.56GlyAla: 2.56 ± 0.613
0.591GlyCys: 0.591 ± 0.347
3.741GlyAsp: 3.741 ± 0.629
3.15GlyGlu: 3.15 ± 0.891
3.15GlyPhe: 3.15 ± 1.153
4.135GlyGly: 4.135 ± 0.913
0.788GlyHis: 0.788 ± 0.375
4.135GlyIle: 4.135 ± 0.735
4.922GlyLys: 4.922 ± 0.856
4.135GlyLeu: 4.135 ± 0.872
1.181GlyMet: 1.181 ± 0.498
3.15GlyAsn: 3.15 ± 0.713
0.197GlyPro: 0.197 ± 0.196
1.181GlyGln: 1.181 ± 0.366
2.953GlyArg: 2.953 ± 0.712
3.938GlySer: 3.938 ± 0.807
1.969GlyThr: 1.969 ± 0.471
2.56GlyVal: 2.56 ± 0.449
0.197GlyTrp: 0.197 ± 0.235
1.772GlyTyr: 1.772 ± 0.639
0.0GlyXaa: 0.0 ± 0.0
His
1.575HisAla: 1.575 ± 0.553
0.591HisCys: 0.591 ± 0.252
1.181HisAsp: 1.181 ± 0.58
1.969HisGlu: 1.969 ± 0.618
1.181HisPhe: 1.181 ± 0.396
0.394HisGly: 0.394 ± 0.332
0.788HisHis: 0.788 ± 0.272
0.591HisIle: 0.591 ± 0.298
1.181HisLys: 1.181 ± 0.255
1.772HisLeu: 1.772 ± 0.485
0.788HisMet: 0.788 ± 0.276
1.181HisAsn: 1.181 ± 0.429
1.575HisPro: 1.575 ± 0.48
0.394HisGln: 0.394 ± 0.398
0.984HisArg: 0.984 ± 0.382
0.788HisSer: 0.788 ± 0.38
1.969HisThr: 1.969 ± 0.47
1.969HisVal: 1.969 ± 0.517
0.0HisTrp: 0.0 ± 0.0
0.591HisTyr: 0.591 ± 0.393
0.0HisXaa: 0.0 ± 0.0
Ile
1.181IleAla: 1.181 ± 0.519
1.181IleCys: 1.181 ± 0.474
4.922IleAsp: 4.922 ± 0.766
2.56IleGlu: 2.56 ± 0.595
3.347IlePhe: 3.347 ± 0.648
2.56IleGly: 2.56 ± 0.599
1.969IleHis: 1.969 ± 0.646
4.332IleIle: 4.332 ± 1.057
6.104IleLys: 6.104 ± 1.545
5.513IleLeu: 5.513 ± 0.758
1.181IleMet: 1.181 ± 0.667
5.513IleAsn: 5.513 ± 0.905
3.741IlePro: 3.741 ± 0.686
2.953IleGln: 2.953 ± 0.573
2.363IleArg: 2.363 ± 0.454
6.3IleSer: 6.3 ± 0.866
3.544IleThr: 3.544 ± 0.6
4.528IleVal: 4.528 ± 0.494
0.394IleTrp: 0.394 ± 0.217
3.938IleTyr: 3.938 ± 0.672
0.0IleXaa: 0.0 ± 0.0
Lys
3.741LysAla: 3.741 ± 0.936
1.378LysCys: 1.378 ± 0.355
4.332LysAsp: 4.332 ± 1.222
4.922LysGlu: 4.922 ± 0.825
5.907LysPhe: 5.907 ± 1.665
3.347LysGly: 3.347 ± 0.807
1.969LysHis: 1.969 ± 0.526
4.922LysIle: 4.922 ± 0.962
4.725LysLys: 4.725 ± 0.959
7.679LysLeu: 7.679 ± 0.859
2.756LysMet: 2.756 ± 0.625
4.725LysAsn: 4.725 ± 1.209
3.741LysPro: 3.741 ± 1.151
2.363LysGln: 2.363 ± 0.429
3.544LysArg: 3.544 ± 0.603
6.3LysSer: 6.3 ± 0.757
3.938LysThr: 3.938 ± 0.791
3.347LysVal: 3.347 ± 0.883
0.197LysTrp: 0.197 ± 0.226
3.938LysTyr: 3.938 ± 1.032
0.0LysXaa: 0.0 ± 0.0
Leu
4.332LeuAla: 4.332 ± 0.938
1.378LeuCys: 1.378 ± 0.433
4.725LeuAsp: 4.725 ± 1.024
4.135LeuGlu: 4.135 ± 0.549
5.513LeuPhe: 5.513 ± 1.866
5.316LeuGly: 5.316 ± 0.782
2.166LeuHis: 2.166 ± 0.676
7.088LeuIle: 7.088 ± 1.875
7.482LeuLys: 7.482 ± 0.783
7.679LeuLeu: 7.679 ± 0.908
3.544LeuMet: 3.544 ± 0.512
7.876LeuAsn: 7.876 ± 0.939
2.56LeuPro: 2.56 ± 0.624
1.772LeuGln: 1.772 ± 0.689
5.119LeuArg: 5.119 ± 0.728
9.057LeuSer: 9.057 ± 0.516
5.316LeuThr: 5.316 ± 0.926
5.316LeuVal: 5.316 ± 0.769
0.591LeuTrp: 0.591 ± 0.267
4.332LeuTyr: 4.332 ± 0.732
0.0LeuXaa: 0.0 ± 0.0
Met
0.788MetAla: 0.788 ± 0.331
0.788MetCys: 0.788 ± 0.34
0.984MetAsp: 0.984 ± 0.421
0.984MetGlu: 0.984 ± 0.548
2.363MetPhe: 2.363 ± 0.651
0.984MetGly: 0.984 ± 0.692
0.197MetHis: 0.197 ± 0.131
2.166MetIle: 2.166 ± 0.6
3.15MetLys: 3.15 ± 0.471
1.772MetLeu: 1.772 ± 0.428
0.984MetMet: 0.984 ± 0.281
2.56MetAsn: 2.56 ± 1.087
0.788MetPro: 0.788 ± 0.264
0.197MetGln: 0.197 ± 0.131
1.575MetArg: 1.575 ± 0.22
2.166MetSer: 2.166 ± 0.522
1.772MetThr: 1.772 ± 0.472
1.969MetVal: 1.969 ± 0.611
0.0MetTrp: 0.0 ± 0.0
0.788MetTyr: 0.788 ± 0.411
0.0MetXaa: 0.0 ± 0.0
Asn
1.772AsnAla: 1.772 ± 0.474
2.166AsnCys: 2.166 ± 0.505
3.938AsnAsp: 3.938 ± 0.596
3.15AsnGlu: 3.15 ± 0.675
3.741AsnPhe: 3.741 ± 1.459
2.166AsnGly: 2.166 ± 0.858
1.378AsnHis: 1.378 ± 0.354
5.513AsnIle: 5.513 ± 0.943
6.891AsnLys: 6.891 ± 1.06
8.269AsnLeu: 8.269 ± 1.853
1.378AsnMet: 1.378 ± 0.71
4.528AsnAsn: 4.528 ± 0.496
3.15AsnPro: 3.15 ± 0.478
1.575AsnGln: 1.575 ± 0.496
2.756AsnArg: 2.756 ± 0.783
4.528AsnSer: 4.528 ± 1.77
3.544AsnThr: 3.544 ± 0.759
7.088AsnVal: 7.088 ± 0.99
1.181AsnTrp: 1.181 ± 0.431
2.953AsnTyr: 2.953 ± 0.738
0.0AsnXaa: 0.0 ± 0.0
Pro
1.181ProAla: 1.181 ± 0.438
0.591ProCys: 0.591 ± 0.393
1.378ProAsp: 1.378 ± 0.453
2.166ProGlu: 2.166 ± 0.495
1.378ProPhe: 1.378 ± 0.481
2.56ProGly: 2.56 ± 0.815
0.394ProHis: 0.394 ± 0.185
2.166ProIle: 2.166 ± 0.602
2.953ProLys: 2.953 ± 0.562
2.953ProLeu: 2.953 ± 0.637
0.591ProMet: 0.591 ± 0.234
2.756ProAsn: 2.756 ± 0.574
1.378ProPro: 1.378 ± 0.591
0.984ProGln: 0.984 ± 0.662
1.969ProArg: 1.969 ± 0.661
2.756ProSer: 2.756 ± 1.167
1.969ProThr: 1.969 ± 0.633
2.363ProVal: 2.363 ± 0.832
0.197ProTrp: 0.197 ± 0.226
1.378ProTyr: 1.378 ± 0.385
0.0ProXaa: 0.0 ± 0.0
Gln
1.378GlnAla: 1.378 ± 0.599
0.788GlnCys: 0.788 ± 0.45
1.575GlnAsp: 1.575 ± 0.467
0.788GlnGlu: 0.788 ± 0.352
2.363GlnPhe: 2.363 ± 0.426
0.984GlnGly: 0.984 ± 0.536
0.197GlnHis: 0.197 ± 0.131
2.166GlnIle: 2.166 ± 0.647
1.181GlnLys: 1.181 ± 0.528
2.756GlnLeu: 2.756 ± 0.647
0.197GlnMet: 0.197 ± 0.277
2.166GlnAsn: 2.166 ± 0.726
2.166GlnPro: 2.166 ± 0.93
0.0GlnGln: 0.0 ± 0.0
2.166GlnArg: 2.166 ± 0.526
1.575GlnSer: 1.575 ± 0.3
0.591GlnThr: 0.591 ± 0.271
0.788GlnVal: 0.788 ± 0.402
0.197GlnTrp: 0.197 ± 0.226
0.984GlnTyr: 0.984 ± 0.42
0.0GlnXaa: 0.0 ± 0.0
Arg
2.363ArgAla: 2.363 ± 0.458
1.575ArgCys: 1.575 ± 0.64
4.528ArgAsp: 4.528 ± 0.799
1.575ArgGlu: 1.575 ± 0.661
3.544ArgPhe: 3.544 ± 0.664
1.772ArgGly: 1.772 ± 0.64
0.788ArgHis: 0.788 ± 0.346
1.575ArgIle: 1.575 ± 0.526
2.363ArgLys: 2.363 ± 0.726
6.891ArgLeu: 6.891 ± 1.193
1.969ArgMet: 1.969 ± 0.662
3.347ArgAsn: 3.347 ± 0.564
1.575ArgPro: 1.575 ± 0.536
1.181ArgGln: 1.181 ± 0.459
1.575ArgArg: 1.575 ± 0.618
3.544ArgSer: 3.544 ± 0.506
2.166ArgThr: 2.166 ± 0.669
4.135ArgVal: 4.135 ± 1.233
0.197ArgTrp: 0.197 ± 0.196
1.969ArgTyr: 1.969 ± 0.407
0.0ArgXaa: 0.0 ± 0.0
Ser
3.544SerAla: 3.544 ± 1.08
0.788SerCys: 0.788 ± 0.26
3.938SerAsp: 3.938 ± 0.924
3.741SerGlu: 3.741 ± 0.729
2.756SerPhe: 2.756 ± 0.935
4.922SerGly: 4.922 ± 0.776
2.953SerHis: 2.953 ± 0.66
5.316SerIle: 5.316 ± 1.221
6.104SerLys: 6.104 ± 0.739
6.3SerLeu: 6.3 ± 2.033
2.363SerMet: 2.363 ± 0.424
5.316SerAsn: 5.316 ± 0.536
1.575SerPro: 1.575 ± 0.492
2.756SerGln: 2.756 ± 1.024
3.741SerArg: 3.741 ± 0.745
4.725SerSer: 4.725 ± 0.979
3.741SerThr: 3.741 ± 0.669
7.088SerVal: 7.088 ± 1.534
0.788SerTrp: 0.788 ± 0.308
2.756SerTyr: 2.756 ± 0.787
0.0SerXaa: 0.0 ± 0.0
Thr
1.969ThrAla: 1.969 ± 0.592
1.575ThrCys: 1.575 ± 0.708
1.969ThrAsp: 1.969 ± 0.597
4.528ThrGlu: 4.528 ± 1.26
2.166ThrPhe: 2.166 ± 0.593
2.953ThrGly: 2.953 ± 0.618
0.984ThrHis: 0.984 ± 0.654
3.15ThrIle: 3.15 ± 0.745
2.56ThrLys: 2.56 ± 0.745
6.694ThrLeu: 6.694 ± 1.345
0.591ThrMet: 0.591 ± 0.252
2.56ThrAsn: 2.56 ± 0.847
1.575ThrPro: 1.575 ± 0.679
1.575ThrGln: 1.575 ± 0.519
2.166ThrArg: 2.166 ± 0.653
3.741ThrSer: 3.741 ± 0.928
2.953ThrThr: 2.953 ± 0.615
3.347ThrVal: 3.347 ± 0.7
1.181ThrTrp: 1.181 ± 0.532
1.969ThrTyr: 1.969 ± 0.918
0.0ThrXaa: 0.0 ± 0.0
Val
1.575ValAla: 1.575 ± 0.426
1.969ValCys: 1.969 ± 0.464
5.71ValAsp: 5.71 ± 0.63
3.347ValGlu: 3.347 ± 0.83
2.56ValPhe: 2.56 ± 1.063
2.953ValGly: 2.953 ± 0.985
1.181ValHis: 1.181 ± 0.419
2.953ValIle: 2.953 ± 0.651
7.088ValLys: 7.088 ± 1.492
4.922ValLeu: 4.922 ± 1.019
2.166ValMet: 2.166 ± 0.513
5.907ValAsn: 5.907 ± 1.152
2.953ValPro: 2.953 ± 0.549
2.166ValGln: 2.166 ± 0.535
3.544ValArg: 3.544 ± 0.919
5.119ValSer: 5.119 ± 0.714
2.756ValThr: 2.756 ± 0.433
4.922ValVal: 4.922 ± 0.941
0.788ValTrp: 0.788 ± 0.302
3.741ValTyr: 3.741 ± 0.673
0.0ValXaa: 0.0 ± 0.0
Trp
0.591TrpAla: 0.591 ± 0.27
0.197TrpCys: 0.197 ± 0.235
0.197TrpAsp: 0.197 ± 0.131
0.788TrpGlu: 0.788 ± 0.362
0.394TrpPhe: 0.394 ± 0.217
0.394TrpGly: 0.394 ± 0.262
0.0TrpHis: 0.0 ± 0.0
0.591TrpIle: 0.591 ± 0.265
0.197TrpLys: 0.197 ± 0.229
1.378TrpLeu: 1.378 ± 0.596
0.394TrpMet: 0.394 ± 0.305
0.394TrpAsn: 0.394 ± 0.335
0.0TrpPro: 0.0 ± 0.0
0.394TrpGln: 0.394 ± 0.361
0.394TrpArg: 0.394 ± 0.345
0.197TrpSer: 0.197 ± 0.235
0.591TrpThr: 0.591 ± 0.393
0.197TrpVal: 0.197 ± 0.196
0.0TrpTrp: 0.0 ± 0.0
0.788TrpTyr: 0.788 ± 0.366
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.166TyrAla: 2.166 ± 0.437
1.378TyrCys: 1.378 ± 0.515
3.347TyrAsp: 3.347 ± 0.797
2.166TyrGlu: 2.166 ± 0.868
3.544TyrPhe: 3.544 ± 0.636
1.969TyrGly: 1.969 ± 0.774
1.378TyrHis: 1.378 ± 0.456
4.135TyrIle: 4.135 ± 0.43
2.56TyrLys: 2.56 ± 0.533
4.528TyrLeu: 4.528 ± 0.743
1.181TyrMet: 1.181 ± 0.326
2.56TyrAsn: 2.56 ± 0.658
1.181TyrPro: 1.181 ± 0.394
0.591TyrGln: 0.591 ± 0.234
1.969TyrArg: 1.969 ± 0.603
2.953TyrSer: 2.953 ± 0.746
2.363TyrThr: 2.363 ± 0.657
2.56TyrVal: 2.56 ± 1.089
0.394TyrTrp: 0.394 ± 0.302
1.969TyrTyr: 1.969 ± 0.488
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 13 proteins (5080 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski