Amino acid dipepetide frequency for Dialister succinatiphilus YIT 11850

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.53AlaAla: 9.53 ± 0.182	1.058AlaCys: 1.058 ± 0.042	4.907AlaAsp: 4.907 ± 0.086	5.658AlaGlu: 5.658 ± 0.113	3.669AlaPhe: 3.669 ± 0.082	7.32AlaGly: 7.32 ± 0.118	1.544AlaHis: 1.544 ± 0.055	4.914AlaIle: 4.914 ± 0.09	4.582AlaLys: 4.582 ± 0.1	8.978AlaLeu: 8.978 ± 0.152	2.835AlaMet: 2.835 ± 0.076	2.243AlaAsn: 2.243 ± 0.067	2.954AlaPro: 2.954 ± 0.081	2.257AlaGln: 2.257 ± 0.063	4.351AlaArg: 4.351 ± 0.085	4.797AlaSer: 4.797 ± 0.106	2.758AlaThr: 2.758 ± 0.071	6.755AlaVal: 6.755 ± 0.116	0.712AlaTrp: 0.712 ± 0.034	2.647AlaTyr: 2.647 ± 0.069	0.0AlaXaa: 0.0 ± 0.0
Cys	0.945CysAla: 0.945 ± 0.034	0.193CysCys: 0.193 ± 0.017	0.586CysAsp: 0.586 ± 0.035	0.534CysGlu: 0.534 ± 0.032	0.622CysPhe: 0.622 ± 0.033	1.259CysGly: 1.259 ± 0.047	0.433CysHis: 0.433 ± 0.031	0.746CysIle: 0.746 ± 0.034	0.439CysLys: 0.439 ± 0.027	1.19CysLeu: 1.19 ± 0.048	0.354CysMet: 0.354 ± 0.024	0.322CysAsn: 0.322 ± 0.021	0.63CysPro: 0.63 ± 0.033	0.371CysGln: 0.371 ± 0.026	0.841CysArg: 0.841 ± 0.035	0.682CysSer: 0.682 ± 0.036	0.602CysThr: 0.602 ± 0.031	0.705CysVal: 0.705 ± 0.034	0.121CysTrp: 0.121 ± 0.015	0.461CysTyr: 0.461 ± 0.026	0.0CysXaa: 0.0 ± 0.0
Asp	4.067AspAla: 4.067 ± 0.1	0.653AspCys: 0.653 ± 0.033	3.035AspAsp: 3.035 ± 0.084	4.101AspGlu: 4.101 ± 0.095	2.842AspPhe: 2.842 ± 0.066	4.447AspGly: 4.447 ± 0.093	1.329AspHis: 1.329 ± 0.049	4.286AspIle: 4.286 ± 0.079	3.528AspLys: 3.528 ± 0.085	4.806AspLeu: 4.806 ± 0.083	2.235AspMet: 2.235 ± 0.067	1.836AspAsn: 1.836 ± 0.06	2.009AspPro: 2.009 ± 0.063	1.318AspGln: 1.318 ± 0.047	3.287AspArg: 3.287 ± 0.073	3.061AspSer: 3.061 ± 0.077	3.176AspThr: 3.176 ± 0.075	4.017AspVal: 4.017 ± 0.093	0.625AspTrp: 0.625 ± 0.029	2.308AspTyr: 2.308 ± 0.06	0.0AspXaa: 0.0 ± 0.0
Glu	6.136GluAla: 6.136 ± 0.115	0.54GluCys: 0.54 ± 0.025	4.053GluAsp: 4.053 ± 0.088	6.849GluGlu: 6.849 ± 0.169	1.87GluPhe: 1.87 ± 0.056	5.584GluGly: 5.584 ± 0.098	1.162GluHis: 1.162 ± 0.043	4.427GluIle: 4.427 ± 0.088	7.041GluLys: 7.041 ± 0.127	5.284GluLeu: 5.284 ± 0.113	2.278GluMet: 2.278 ± 0.056	3.125GluAsn: 3.125 ± 0.063	1.801GluPro: 1.801 ± 0.061	1.702GluGln: 1.702 ± 0.064	3.448GluArg: 3.448 ± 0.081	3.052GluSer: 3.052 ± 0.076	3.432GluThr: 3.432 ± 0.071	3.941GluVal: 3.941 ± 0.081	0.592GluTrp: 0.592 ± 0.031	1.921GluTyr: 1.921 ± 0.058	0.0GluXaa: 0.0 ± 0.0
Phe	3.118PheAla: 3.118 ± 0.073	0.681PheCys: 0.681 ± 0.034	2.385PheAsp: 2.385 ± 0.063	1.912PheGlu: 1.912 ± 0.051	2.133PhePhe: 2.133 ± 0.074	3.101PheGly: 3.101 ± 0.067	1.298PheHis: 1.298 ± 0.044	2.866PheIle: 2.866 ± 0.082	2.022PheLys: 2.022 ± 0.062	4.769PheLeu: 4.769 ± 0.116	1.301PheMet: 1.301 ± 0.05	1.343PheAsn: 1.343 ± 0.04	1.705PhePro: 1.705 ± 0.045	1.18PheGln: 1.18 ± 0.041	2.017PheArg: 2.017 ± 0.053	2.854PheSer: 2.854 ± 0.062	2.444PheThr: 2.444 ± 0.052	2.255PheVal: 2.255 ± 0.065	0.534PheTrp: 0.534 ± 0.033	1.578PheTyr: 1.578 ± 0.05	0.0PheXaa: 0.0 ± 0.0
Gly	6.105GlyAla: 6.105 ± 0.118	1.152GlyCys: 1.152 ± 0.046	4.045GlyAsp: 4.045 ± 0.091	4.696GlyGlu: 4.696 ± 0.086	3.183GlyPhe: 3.183 ± 0.066	5.723GlyGly: 5.723 ± 0.113	1.915GlyHis: 1.915 ± 0.055	5.816GlyIle: 5.816 ± 0.106	6.03GlyLys: 6.03 ± 0.102	6.863GlyLeu: 6.863 ± 0.105	2.597GlyMet: 2.597 ± 0.068	2.854GlyAsn: 2.854 ± 0.08	2.062GlyPro: 2.062 ± 0.063	2.033GlyGln: 2.033 ± 0.061	4.337GlyArg: 4.337 ± 0.087	4.637GlySer: 4.637 ± 0.097	4.54GlyThr: 4.54 ± 0.112	5.021GlyVal: 5.021 ± 0.095	0.871GlyTrp: 0.871 ± 0.037	2.826GlyTyr: 2.826 ± 0.068	0.0GlyXaa: 0.0 ± 0.0
His	1.551HisAla: 1.551 ± 0.051	0.295HisCys: 0.295 ± 0.024	1.205HisAsp: 1.205 ± 0.046	1.381HisGlu: 1.381 ± 0.048	1.18HisPhe: 1.18 ± 0.037	1.742HisGly: 1.742 ± 0.058	0.759HisHis: 0.759 ± 0.051	1.725HisIle: 1.725 ± 0.052	1.16HisLys: 1.16 ± 0.051	2.224HisLeu: 2.224 ± 0.063	0.832HisMet: 0.832 ± 0.039	0.755HisAsn: 0.755 ± 0.034	1.319HisPro: 1.319 ± 0.048	0.603HisGln: 0.603 ± 0.028	1.202HisArg: 1.202 ± 0.046	1.191HisSer: 1.191 ± 0.047	1.171HisThr: 1.171 ± 0.043	1.675HisVal: 1.675 ± 0.051	0.26HisTrp: 0.26 ± 0.018	0.838HisTyr: 0.838 ± 0.037	0.0HisXaa: 0.0 ± 0.0
Ile	5.197IleAla: 5.197 ± 0.104	1.05IleCys: 1.05 ± 0.043	3.487IleAsp: 3.487 ± 0.084	3.468IleGlu: 3.468 ± 0.076	2.667IlePhe: 2.667 ± 0.07	4.856IleGly: 4.856 ± 0.098	1.937IleHis: 1.937 ± 0.058	4.348IleIle: 4.348 ± 0.091	2.962IleLys: 2.962 ± 0.08	6.63IleLeu: 6.63 ± 0.117	1.841IleMet: 1.841 ± 0.055	2.142IleAsn: 2.142 ± 0.062	3.553IlePro: 3.553 ± 0.088	1.83IleGln: 1.83 ± 0.052	3.89IleArg: 3.89 ± 0.08	4.67IleSer: 4.67 ± 0.09	3.712IleThr: 3.712 ± 0.078	4.064IleVal: 4.064 ± 0.088	0.608IleTrp: 0.608 ± 0.029	2.345IleTyr: 2.345 ± 0.065	0.0IleXaa: 0.0 ± 0.0
Lys	6.09LysAla: 6.09 ± 0.106	0.49LysCys: 0.49 ± 0.029	4.487LysAsp: 4.487 ± 0.083	6.542LysGlu: 6.542 ± 0.112	1.474LysPhe: 1.474 ± 0.045	5.324LysGly: 5.324 ± 0.093	0.967LysHis: 0.967 ± 0.038	3.728LysIle: 3.728 ± 0.073	5.918LysLys: 5.918 ± 0.107	4.871LysLeu: 4.871 ± 0.093	2.169LysMet: 2.169 ± 0.057	3.033LysAsn: 3.033 ± 0.083	2.221LysPro: 2.221 ± 0.068	1.913LysGln: 1.913 ± 0.063	3.012LysArg: 3.012 ± 0.073	3.259LysSer: 3.259 ± 0.071	3.436LysThr: 3.436 ± 0.074	4.381LysVal: 4.381 ± 0.085	0.653LysTrp: 0.653 ± 0.033	2.161LysTyr: 2.161 ± 0.057	0.0LysXaa: 0.0 ± 0.0
Leu	8.526LeuAla: 8.526 ± 0.111	1.253LeuCys: 1.253 ± 0.053	5.052LeuAsp: 5.052 ± 0.087	5.501LeuGlu: 5.501 ± 0.099	4.378LeuPhe: 4.378 ± 0.11	6.738LeuGly: 6.738 ± 0.129	2.181LeuHis: 2.181 ± 0.067	5.392LeuIle: 5.392 ± 0.098	5.91LeuLys: 5.91 ± 0.096	9.168LeuLeu: 9.168 ± 0.207	2.749LeuMet: 2.749 ± 0.073	2.755LeuAsn: 2.755 ± 0.073	4.492LeuPro: 4.492 ± 0.082	2.568LeuGln: 2.568 ± 0.066	4.15LeuArg: 4.15 ± 0.1	7.527LeuSer: 7.527 ± 0.12	5.398LeuThr: 5.398 ± 0.103	5.519LeuVal: 5.519 ± 0.102	1.036LeuTrp: 1.036 ± 0.047	3.321LeuTyr: 3.321 ± 0.068	0.0LeuXaa: 0.0 ± 0.0
Met	3.439MetAla: 3.439 ± 0.092	0.266MetCys: 0.266 ± 0.022	2.274MetAsp: 2.274 ± 0.055	2.628MetGlu: 2.628 ± 0.075	0.769MetPhe: 0.769 ± 0.035	2.382MetGly: 2.382 ± 0.071	0.554MetHis: 0.554 ± 0.027	1.975MetIle: 1.975 ± 0.059	3.091MetLys: 3.091 ± 0.07	2.159MetLeu: 2.159 ± 0.062	1.016MetMet: 1.016 ± 0.046	1.598MetAsn: 1.598 ± 0.047	1.203MetPro: 1.203 ± 0.043	0.868MetGln: 0.868 ± 0.042	1.207MetArg: 1.207 ± 0.047	1.615MetSer: 1.615 ± 0.049	1.98MetThr: 1.98 ± 0.06	2.181MetVal: 2.181 ± 0.056	0.19MetTrp: 0.19 ± 0.017	0.862MetTyr: 0.862 ± 0.038	0.0MetXaa: 0.0 ± 0.0
Asn	2.828AsnAla: 2.828 ± 0.086	0.398AsnCys: 0.398 ± 0.026	1.838AsnAsp: 1.838 ± 0.059	2.178AsnGlu: 2.178 ± 0.065	1.33AsnPhe: 1.33 ± 0.051	2.951AsnGly: 2.951 ± 0.103	1.016AsnHis: 1.016 ± 0.041	2.354AsnIle: 2.354 ± 0.069	1.958AsnLys: 1.958 ± 0.062	3.248AsnLeu: 3.248 ± 0.074	1.126AsnMet: 1.126 ± 0.039	1.148AsnAsn: 1.148 ± 0.053	2.06AsnPro: 2.06 ± 0.058	1.18AsnGln: 1.18 ± 0.042	2.07AsnArg: 2.07 ± 0.053	1.76AsnSer: 1.76 ± 0.059	1.746AsnThr: 1.746 ± 0.068	2.289AsnVal: 2.289 ± 0.067	0.435AsnTrp: 0.435 ± 0.029	1.452AsnTyr: 1.452 ± 0.047	0.0AsnXaa: 0.0 ± 0.0
Pro	3.355ProAla: 3.355 ± 0.083	0.442ProCys: 0.442 ± 0.028	2.521ProAsp: 2.521 ± 0.06	3.414ProGlu: 3.414 ± 0.073	2.051ProPhe: 2.051 ± 0.057	2.922ProGly: 2.922 ± 0.069	0.883ProHis: 0.883 ± 0.037	2.099ProIle: 2.099 ± 0.066	2.119ProLys: 2.119 ± 0.059	3.977ProLeu: 3.977 ± 0.091	1.095ProMet: 1.095 ± 0.042	1.077ProAsn: 1.077 ± 0.043	1.343ProPro: 1.343 ± 0.051	1.087ProGln: 1.087 ± 0.046	1.626ProArg: 1.626 ± 0.051	2.521ProSer: 2.521 ± 0.063	1.487ProThr: 1.487 ± 0.054	3.683ProVal: 3.683 ± 0.081	0.512ProTrp: 0.512 ± 0.027	1.524ProTyr: 1.524 ± 0.048	0.0ProXaa: 0.0 ± 0.0
Gln	2.34GlnAla: 2.34 ± 0.065	0.282GlnCys: 0.282 ± 0.02	1.437GlnAsp: 1.437 ± 0.049	1.983GlnGlu: 1.983 ± 0.064	1.033GlnPhe: 1.033 ± 0.043	2.029GlnGly: 2.029 ± 0.056	0.49GlnHis: 0.49 ± 0.026	1.825GlnIle: 1.825 ± 0.051	2.343GlnLys: 2.343 ± 0.058	2.367GlnLeu: 2.367 ± 0.072	0.957GlnMet: 0.957 ± 0.038	1.171GlnAsn: 1.171 ± 0.048	0.936GlnPro: 0.936 ± 0.041	1.005GlnGln: 1.005 ± 0.049	1.452GlnArg: 1.452 ± 0.053	1.542GlnSer: 1.542 ± 0.049	1.37GlnThr: 1.37 ± 0.051	2.04GlnVal: 2.04 ± 0.053	0.333GlnTrp: 0.333 ± 0.025	1.013GlnTyr: 1.013 ± 0.037	0.0GlnXaa: 0.0 ± 0.0
Arg	3.607ArgAla: 3.607 ± 0.077	0.591ArgCys: 0.591 ± 0.029	2.826ArgAsp: 2.826 ± 0.066	3.869ArgGlu: 3.869 ± 0.08	2.302ArgPhe: 2.302 ± 0.055	3.176ArgGly: 3.176 ± 0.072	1.128ArgHis: 1.128 ± 0.043	3.553ArgIle: 3.553 ± 0.084	4.248ArgLys: 4.248 ± 0.082	4.916ArgLeu: 4.916 ± 0.09	1.757ArgMet: 1.757 ± 0.048	2.26ArgAsn: 2.26 ± 0.065	1.861ArgPro: 1.861 ± 0.054	2.048ArgGln: 2.048 ± 0.072	3.123ArgArg: 3.123 ± 0.087	2.733ArgSer: 2.733 ± 0.077	2.342ArgThr: 2.342 ± 0.057	3.021ArgVal: 3.021 ± 0.066	0.614ArgTrp: 0.614 ± 0.027	1.879ArgTyr: 1.879 ± 0.066	0.0ArgXaa: 0.0 ± 0.0
Ser	4.688SerAla: 4.688 ± 0.086	0.73SerCys: 0.73 ± 0.036	3.134SerAsp: 3.134 ± 0.07	3.191SerGlu: 3.191 ± 0.06	3.001SerPhe: 3.001 ± 0.083	5.067SerGly: 5.067 ± 0.103	1.547SerHis: 1.547 ± 0.051	3.926SerIle: 3.926 ± 0.089	2.645SerLys: 2.645 ± 0.073	6.331SerLeu: 6.331 ± 0.101	1.923SerMet: 1.923 ± 0.056	1.604SerAsn: 1.604 ± 0.058	2.441SerPro: 2.441 ± 0.07	1.736SerGln: 1.736 ± 0.054	3.581SerArg: 3.581 ± 0.075	3.985SerSer: 3.985 ± 0.087	2.825SerThr: 2.825 ± 0.073	3.986SerVal: 3.986 ± 0.089	0.759SerTrp: 0.759 ± 0.037	2.382SerTyr: 2.382 ± 0.072	0.0SerXaa: 0.0 ± 0.0
Thr	5.021ThrAla: 5.021 ± 0.108	0.565ThrCys: 0.565 ± 0.03	2.896ThrAsp: 2.896 ± 0.068	3.18ThrGlu: 3.18 ± 0.072	2.155ThrPhe: 2.155 ± 0.052	4.65ThrGly: 4.65 ± 0.091	1.055ThrHis: 1.055 ± 0.04	3.59ThrIle: 3.59 ± 0.084	2.665ThrLys: 2.665 ± 0.064	5.097ThrLeu: 5.097 ± 0.089	1.562ThrMet: 1.562 ± 0.052	1.618ThrAsn: 1.618 ± 0.059	2.317ThrPro: 2.317 ± 0.066	1.012ThrGln: 1.012 ± 0.043	2.331ThrArg: 2.331 ± 0.06	2.691ThrSer: 2.691 ± 0.071	2.487ThrThr: 2.487 ± 0.08	4.116ThrVal: 4.116 ± 0.093	0.571ThrTrp: 0.571 ± 0.031	1.913ThrTyr: 1.913 ± 0.063	0.0ThrXaa: 0.0 ± 0.0
Val	4.637ValAla: 4.637 ± 0.095	0.828ValCys: 0.828 ± 0.039	3.842ValAsp: 3.842 ± 0.087	4.274ValGlu: 4.274 ± 0.086	2.681ValPhe: 2.681 ± 0.062	4.138ValGly: 4.138 ± 0.093	1.556ValHis: 1.556 ± 0.049	4.75ValIle: 4.75 ± 0.085	4.707ValLys: 4.707 ± 0.094	6.639ValLeu: 6.639 ± 0.097	2.116ValMet: 2.116 ± 0.056	2.579ValAsn: 2.579 ± 0.064	2.973ValPro: 2.973 ± 0.064	1.723ValGln: 1.723 ± 0.053	3.273ValArg: 3.273 ± 0.082	4.498ValSer: 4.498 ± 0.095	4.153ValThr: 4.153 ± 0.085	4.549ValVal: 4.549 ± 0.104	0.642ValTrp: 0.642 ± 0.033	2.48ValTyr: 2.48 ± 0.062	0.0ValXaa: 0.0 ± 0.0
Trp	0.735TrpAla: 0.735 ± 0.035	0.124TrpCys: 0.124 ± 0.014	0.63TrpAsp: 0.63 ± 0.031	0.623TrpGlu: 0.623 ± 0.029	0.439TrpPhe: 0.439 ± 0.028	0.752TrpGly: 0.752 ± 0.033	0.291TrpHis: 0.291 ± 0.023	0.678TrpIle: 0.678 ± 0.033	0.857TrpLys: 0.857 ± 0.034	0.953TrpLeu: 0.953 ± 0.044	0.447TrpMet: 0.447 ± 0.029	0.558TrpAsn: 0.558 ± 0.029	0.337TrpPro: 0.337 ± 0.022	0.495TrpGln: 0.495 ± 0.031	0.504TrpArg: 0.504 ± 0.028	0.541TrpSer: 0.541 ± 0.034	0.541TrpThr: 0.541 ± 0.028	0.538TrpVal: 0.538 ± 0.029	0.131TrpTrp: 0.131 ± 0.014	0.387TrpTyr: 0.387 ± 0.028	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.551TyrAla: 2.551 ± 0.061	0.445TyrCys: 0.445 ± 0.025	2.326TyrAsp: 2.326 ± 0.062	2.257TyrGlu: 2.257 ± 0.052	1.717TyrPhe: 1.717 ± 0.044	3.146TyrGly: 3.146 ± 0.068	1.027TyrHis: 1.027 ± 0.042	2.257TyrIle: 2.257 ± 0.069	1.903TyrLys: 1.903 ± 0.063	3.145TyrLeu: 3.145 ± 0.074	1.063TyrMet: 1.063 ± 0.043	1.349TyrAsn: 1.349 ± 0.051	1.521TyrPro: 1.521 ± 0.056	1.022TyrGln: 1.022 ± 0.035	2.15TyrArg: 2.15 ± 0.061	1.864TyrSer: 1.864 ± 0.067	1.892TyrThr: 1.892 ± 0.055	2.3TyrVal: 2.3 ± 0.061	0.364TyrTrp: 0.364 ± 0.023	1.378TyrTyr: 1.378 ± 0.05	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2140 proteins (646481 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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