Amino acid dipepetide frequency for Beihai noda-like virus 5

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.468AlaAla: 9.468 ± 2.304
2.185AlaCys: 2.185 ± 0.322
4.37AlaAsp: 4.37 ± 0.719
6.555AlaGlu: 6.555 ± 0.396
5.827AlaPhe: 5.827 ± 2.775
5.098AlaGly: 5.098 ± 0.297
2.913AlaHis: 2.913 ± 1.338
2.185AlaIle: 2.185 ± 1.041
5.827AlaLys: 5.827 ± 0.05
6.555AlaLeu: 6.555 ± 0.396
0.728AlaMet: 0.728 ± 0.347
4.37AlaAsn: 4.37 ± 2.007
4.37AlaPro: 4.37 ± 3.369
1.457AlaGln: 1.457 ± 2.032
3.642AlaArg: 3.642 ± 0.991
4.37AlaSer: 4.37 ± 0.719
3.642AlaThr: 3.642 ± 0.991
4.37AlaVal: 4.37 ± 0.719
0.0AlaTrp: 0.0 ± 0.0
1.457AlaTyr: 1.457 ± 0.694
0.0AlaXaa: 0.0 ± 0.0
Cys
1.457CysAla: 1.457 ± 0.694
0.0CysCys: 0.0 ± 0.0
2.185CysAsp: 2.185 ± 1.041
2.185CysGlu: 2.185 ± 1.041
0.728CysPhe: 0.728 ± 0.347
2.185CysGly: 2.185 ± 0.322
0.728CysHis: 0.728 ± 1.016
0.0CysIle: 0.0 ± 0.0
0.728CysLys: 0.728 ± 0.347
0.728CysLeu: 0.728 ± 0.347
0.728CysMet: 0.728 ± 0.347
0.0CysAsn: 0.0 ± 0.0
2.185CysPro: 2.185 ± 0.322
0.0CysGln: 0.0 ± 0.0
0.728CysArg: 0.728 ± 0.347
0.728CysSer: 0.728 ± 0.347
0.0CysThr: 0.0 ± 0.0
2.185CysVal: 2.185 ± 0.322
0.728CysTrp: 0.728 ± 0.347
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.913AspAla: 2.913 ± 1.338
1.457AspCys: 1.457 ± 0.694
5.098AspAsp: 5.098 ± 1.065
2.913AspGlu: 2.913 ± 0.025
1.457AspPhe: 1.457 ± 0.669
5.098AspGly: 5.098 ± 0.297
0.0AspHis: 0.0 ± 0.0
1.457AspIle: 1.457 ± 0.694
2.185AspLys: 2.185 ± 1.041
5.827AspLeu: 5.827 ± 1.412
2.185AspMet: 2.185 ± 1.041
4.37AspAsn: 4.37 ± 2.007
2.185AspPro: 2.185 ± 1.685
2.185AspGln: 2.185 ± 1.041
3.642AspArg: 3.642 ± 0.372
2.913AspSer: 2.913 ± 1.387
3.642AspThr: 3.642 ± 0.372
6.555AspVal: 6.555 ± 1.759
0.0AspTrp: 0.0 ± 0.0
4.37AspTyr: 4.37 ± 0.644
0.0AspXaa: 0.0 ± 0.0
Glu
2.913GluAla: 2.913 ± 1.387
0.728GluCys: 0.728 ± 0.347
2.185GluAsp: 2.185 ± 0.322
4.37GluGlu: 4.37 ± 2.081
0.728GluPhe: 0.728 ± 0.347
2.185GluGly: 2.185 ± 1.041
0.728GluHis: 0.728 ± 0.347
5.098GluIle: 5.098 ± 1.66
2.185GluLys: 2.185 ± 0.322
5.827GluLeu: 5.827 ± 0.05
0.728GluMet: 0.728 ± 0.585
2.913GluAsn: 2.913 ± 0.025
2.185GluPro: 2.185 ± 1.041
2.185GluGln: 2.185 ± 1.041
4.37GluArg: 4.37 ± 0.719
3.642GluSer: 3.642 ± 0.372
2.185GluThr: 2.185 ± 0.322
5.827GluVal: 5.827 ± 1.412
1.457GluTrp: 1.457 ± 0.694
0.728GluTyr: 0.728 ± 0.347
0.0GluXaa: 0.0 ± 0.0
Phe
1.457PheAla: 1.457 ± 2.032
0.728PheCys: 0.728 ± 0.347
1.457PheAsp: 1.457 ± 0.694
6.555PheGlu: 6.555 ± 1.759
1.457PhePhe: 1.457 ± 0.694
3.642PheGly: 3.642 ± 0.372
1.457PheHis: 1.457 ± 0.694
1.457PheIle: 1.457 ± 0.694
1.457PheLys: 1.457 ± 0.669
2.185PheLeu: 2.185 ± 0.322
0.728PheMet: 0.728 ± 0.347
2.913PheAsn: 2.913 ± 1.387
3.642PhePro: 3.642 ± 0.991
2.913PheGln: 2.913 ± 0.025
2.185PheArg: 2.185 ± 1.041
6.555PheSer: 6.555 ± 2.329
4.37PheThr: 4.37 ± 3.369
3.642PheVal: 3.642 ± 0.372
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.37GlyAla: 4.37 ± 2.081
1.457GlyCys: 1.457 ± 0.694
3.642GlyAsp: 3.642 ± 0.991
2.185GlyGlu: 2.185 ± 1.041
4.37GlyPhe: 4.37 ± 0.719
5.098GlyGly: 5.098 ± 4.385
0.728GlyHis: 0.728 ± 0.347
1.457GlyIle: 1.457 ± 0.694
2.185GlyLys: 2.185 ± 1.041
3.642GlyLeu: 3.642 ± 0.991
1.457GlyMet: 1.457 ± 0.694
0.728GlyAsn: 0.728 ± 1.016
3.642GlyPro: 3.642 ± 0.372
1.457GlyGln: 1.457 ± 0.669
5.098GlyArg: 5.098 ± 1.66
4.37GlySer: 4.37 ± 0.644
4.37GlyThr: 4.37 ± 2.007
2.913GlyVal: 2.913 ± 1.338
0.728GlyTrp: 0.728 ± 0.347
5.827GlyTyr: 5.827 ± 0.05
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.728HisAsp: 0.728 ± 0.347
0.0HisGlu: 0.0 ± 0.0
0.728HisPhe: 0.728 ± 0.347
1.457HisGly: 1.457 ± 0.694
0.0HisHis: 0.0 ± 0.0
2.185HisIle: 2.185 ± 0.322
0.0HisLys: 0.0 ± 0.0
0.0HisLeu: 0.0 ± 0.0
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
3.642HisPro: 3.642 ± 0.372
0.0HisGln: 0.0 ± 0.0
2.185HisArg: 2.185 ± 1.685
0.728HisSer: 0.728 ± 0.347
1.457HisThr: 1.457 ± 0.694
2.913HisVal: 2.913 ± 0.025
2.185HisTrp: 2.185 ± 1.685
1.457HisTyr: 1.457 ± 0.694
0.0HisXaa: 0.0 ± 0.0
Ile
2.913IleAla: 2.913 ± 1.338
2.185IleCys: 2.185 ± 1.041
2.913IleAsp: 2.913 ± 1.338
0.728IleGlu: 0.728 ± 0.347
0.728IlePhe: 0.728 ± 0.347
2.185IleGly: 2.185 ± 0.322
0.0IleHis: 0.0 ± 0.0
2.913IleIle: 2.913 ± 1.387
4.37IleLys: 4.37 ± 0.719
4.37IleLeu: 4.37 ± 2.081
0.728IleMet: 0.728 ± 1.016
2.185IleAsn: 2.185 ± 1.041
1.457IlePro: 1.457 ± 0.669
2.185IleGln: 2.185 ± 1.041
2.913IleArg: 2.913 ± 1.387
5.098IleSer: 5.098 ± 1.065
3.642IleThr: 3.642 ± 2.354
3.642IleVal: 3.642 ± 2.354
0.0IleTrp: 0.0 ± 0.0
0.728IleTyr: 0.728 ± 0.347
0.0IleXaa: 0.0 ± 0.0
Lys
5.098LysAla: 5.098 ± 0.297
0.728LysCys: 0.728 ± 0.347
2.913LysAsp: 2.913 ± 0.025
1.457LysGlu: 1.457 ± 0.694
4.37LysPhe: 4.37 ± 0.644
2.185LysGly: 2.185 ± 0.322
0.0LysHis: 0.0 ± 0.0
0.728LysIle: 0.728 ± 0.347
2.913LysLys: 2.913 ± 1.387
3.642LysLeu: 3.642 ± 1.734
2.185LysMet: 2.185 ± 1.041
1.457LysAsn: 1.457 ± 0.694
2.185LysPro: 2.185 ± 0.322
1.457LysGln: 1.457 ± 0.694
0.728LysArg: 0.728 ± 0.347
1.457LysSer: 1.457 ± 0.694
3.642LysThr: 3.642 ± 2.354
3.642LysVal: 3.642 ± 1.734
0.0LysTrp: 0.0 ± 0.0
2.185LysTyr: 2.185 ± 0.322
0.0LysXaa: 0.0 ± 0.0
Leu
8.74LeuAla: 8.74 ± 1.288
0.728LeuCys: 0.728 ± 0.347
5.827LeuAsp: 5.827 ± 1.412
5.098LeuGlu: 5.098 ± 0.297
3.642LeuPhe: 3.642 ± 0.372
4.37LeuGly: 4.37 ± 0.719
1.457LeuHis: 1.457 ± 0.669
4.37LeuIle: 4.37 ± 0.644
5.098LeuLys: 5.098 ± 1.065
6.555LeuLeu: 6.555 ± 0.396
1.457LeuMet: 1.457 ± 2.032
1.457LeuAsn: 1.457 ± 0.694
2.913LeuPro: 2.913 ± 0.025
3.642LeuGln: 3.642 ± 0.991
5.827LeuArg: 5.827 ± 0.05
5.098LeuSer: 5.098 ± 1.065
1.457LeuThr: 1.457 ± 0.694
4.37LeuVal: 4.37 ± 0.719
0.0LeuTrp: 0.0 ± 0.0
4.37LeuTyr: 4.37 ± 2.007
0.0LeuXaa: 0.0 ± 0.0
Met
3.642MetAla: 3.642 ± 0.372
0.728MetCys: 0.728 ± 1.016
0.728MetAsp: 0.728 ± 0.347
1.457MetGlu: 1.457 ± 0.694
1.457MetPhe: 1.457 ± 0.694
1.457MetGly: 1.457 ± 0.694
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.728MetLys: 0.728 ± 1.016
1.457MetLeu: 1.457 ± 0.669
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
1.457MetArg: 1.457 ± 0.694
0.728MetSer: 0.728 ± 0.347
2.185MetThr: 2.185 ± 0.322
2.185MetVal: 2.185 ± 1.041
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.457AsnAla: 1.457 ± 0.694
0.728AsnCys: 0.728 ± 0.347
2.913AsnAsp: 2.913 ± 0.025
0.728AsnGlu: 0.728 ± 0.347
0.0AsnPhe: 0.0 ± 0.0
2.185AsnGly: 2.185 ± 1.041
2.185AsnHis: 2.185 ± 0.322
1.457AsnIle: 1.457 ± 0.669
1.457AsnLys: 1.457 ± 0.694
2.913AsnLeu: 2.913 ± 0.025
0.0AsnMet: 0.0 ± 0.0
1.457AsnAsn: 1.457 ± 0.694
5.827AsnPro: 5.827 ± 1.313
0.0AsnGln: 0.0 ± 0.0
1.457AsnArg: 1.457 ± 0.669
5.827AsnSer: 5.827 ± 1.313
3.642AsnThr: 3.642 ± 1.734
2.185AsnVal: 2.185 ± 1.041
0.728AsnTrp: 0.728 ± 1.016
0.728AsnTyr: 0.728 ± 1.016
0.0AsnXaa: 0.0 ± 0.0
Pro
3.642ProAla: 3.642 ± 0.991
0.0ProCys: 0.0 ± 0.0
2.913ProAsp: 2.913 ± 0.025
4.37ProGlu: 4.37 ± 0.644
3.642ProPhe: 3.642 ± 2.354
2.185ProGly: 2.185 ± 1.685
0.0ProHis: 0.0 ± 0.0
1.457ProIle: 1.457 ± 0.669
2.185ProLys: 2.185 ± 0.322
5.098ProLeu: 5.098 ± 1.065
1.457ProMet: 1.457 ± 0.694
1.457ProAsn: 1.457 ± 2.032
2.913ProPro: 2.913 ± 2.7
2.185ProGln: 2.185 ± 1.041
4.37ProArg: 4.37 ± 2.007
8.74ProSer: 8.74 ± 4.013
2.913ProThr: 2.913 ± 2.7
10.925ProVal: 10.925 ± 2.478
2.185ProTrp: 2.185 ± 0.322
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.457GlnAla: 1.457 ± 2.032
0.0GlnCys: 0.0 ± 0.0
0.728GlnAsp: 0.728 ± 0.347
0.728GlnGlu: 0.728 ± 0.347
1.457GlnPhe: 1.457 ± 0.669
1.457GlnGly: 1.457 ± 2.032
1.457GlnHis: 1.457 ± 0.669
0.728GlnIle: 0.728 ± 0.347
0.728GlnLys: 0.728 ± 0.347
0.728GlnLeu: 0.728 ± 0.347
0.0GlnMet: 0.0 ± 0.0
0.728GlnAsn: 0.728 ± 0.347
3.642GlnPro: 3.642 ± 0.372
1.457GlnGln: 1.457 ± 0.669
6.555GlnArg: 6.555 ± 1.759
2.913GlnSer: 2.913 ± 0.025
1.457GlnThr: 1.457 ± 0.669
4.37GlnVal: 4.37 ± 2.081
0.0GlnTrp: 0.0 ± 0.0
1.457GlnTyr: 1.457 ± 0.694
0.0GlnXaa: 0.0 ± 0.0
Arg
6.555ArgAla: 6.555 ± 0.966
0.728ArgCys: 0.728 ± 0.347
2.185ArgAsp: 2.185 ± 1.041
0.728ArgGlu: 0.728 ± 0.347
5.098ArgPhe: 5.098 ± 3.023
4.37ArgGly: 4.37 ± 2.007
0.0ArgHis: 0.0 ± 0.0
5.098ArgIle: 5.098 ± 0.297
3.642ArgLys: 3.642 ± 0.372
6.555ArgLeu: 6.555 ± 3.691
2.185ArgMet: 2.185 ± 1.041
2.185ArgAsn: 2.185 ± 1.041
4.37ArgPro: 4.37 ± 0.719
3.642ArgGln: 3.642 ± 0.372
3.642ArgArg: 3.642 ± 1.734
3.642ArgSer: 3.642 ± 0.372
2.185ArgThr: 2.185 ± 1.041
4.37ArgVal: 4.37 ± 0.719
2.185ArgTrp: 2.185 ± 1.041
3.642ArgTyr: 3.642 ± 0.372
0.0ArgXaa: 0.0 ± 0.0
Ser
6.555SerAla: 6.555 ± 1.759
2.185SerCys: 2.185 ± 1.041
6.555SerAsp: 6.555 ± 0.396
5.098SerGlu: 5.098 ± 1.66
3.642SerPhe: 3.642 ± 1.734
5.098SerGly: 5.098 ± 0.297
2.913SerHis: 2.913 ± 1.387
4.37SerIle: 4.37 ± 0.719
2.913SerLys: 2.913 ± 0.025
5.827SerLeu: 5.827 ± 0.05
0.728SerMet: 0.728 ± 0.574
3.642SerAsn: 3.642 ± 0.991
6.555SerPro: 6.555 ± 3.691
1.457SerGln: 1.457 ± 0.694
6.555SerArg: 6.555 ± 0.396
6.555SerSer: 6.555 ± 2.329
8.012SerThr: 8.012 ± 4.36
4.37SerVal: 4.37 ± 0.719
1.457SerTrp: 1.457 ± 0.669
2.185SerTyr: 2.185 ± 1.041
0.0SerXaa: 0.0 ± 0.0
Thr
4.37ThrAla: 4.37 ± 2.007
1.457ThrCys: 1.457 ± 0.669
5.098ThrAsp: 5.098 ± 0.297
2.185ThrGlu: 2.185 ± 0.322
2.913ThrPhe: 2.913 ± 0.025
2.185ThrGly: 2.185 ± 0.322
0.0ThrHis: 0.0 ± 0.0
6.555ThrIle: 6.555 ± 2.329
1.457ThrLys: 1.457 ± 0.694
4.37ThrLeu: 4.37 ± 3.369
0.0ThrMet: 0.0 ± 0.0
2.185ThrAsn: 2.185 ± 0.322
5.098ThrPro: 5.098 ± 1.66
0.728ThrGln: 0.728 ± 1.016
2.913ThrArg: 2.913 ± 0.025
8.012ThrSer: 8.012 ± 4.36
2.913ThrThr: 2.913 ± 1.387
3.642ThrVal: 3.642 ± 1.734
0.0ThrTrp: 0.0 ± 0.0
1.457ThrTyr: 1.457 ± 0.694
0.0ThrXaa: 0.0 ± 0.0
Val
6.555ValAla: 6.555 ± 0.396
2.185ValCys: 2.185 ± 0.322
5.098ValAsp: 5.098 ± 1.065
6.555ValGlu: 6.555 ± 3.122
5.827ValPhe: 5.827 ± 2.676
3.642ValGly: 3.642 ± 1.734
2.185ValHis: 2.185 ± 1.041
3.642ValIle: 3.642 ± 1.734
2.185ValLys: 2.185 ± 1.041
7.283ValLeu: 7.283 ± 0.743
1.457ValMet: 1.457 ± 0.694
2.185ValAsn: 2.185 ± 1.041
2.913ValPro: 2.913 ± 1.338
2.185ValGln: 2.185 ± 0.322
6.555ValArg: 6.555 ± 0.396
9.468ValSer: 9.468 ± 1.784
2.913ValThr: 2.913 ± 1.387
6.555ValVal: 6.555 ± 3.122
1.457ValTrp: 1.457 ± 0.694
2.185ValTyr: 2.185 ± 1.041
0.0ValXaa: 0.0 ± 0.0
Trp
1.457TrpAla: 1.457 ± 0.694
0.0TrpCys: 0.0 ± 0.0
0.728TrpAsp: 0.728 ± 0.347
0.0TrpGlu: 0.0 ± 0.0
0.728TrpPhe: 0.728 ± 0.347
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.728TrpIle: 0.728 ± 0.347
0.728TrpLys: 0.728 ± 1.016
1.457TrpLeu: 1.457 ± 0.694
0.0TrpMet: 0.0 ± 0.0
1.457TrpAsn: 1.457 ± 0.694
1.457TrpPro: 1.457 ± 0.669
1.457TrpGln: 1.457 ± 0.669
0.728TrpArg: 0.728 ± 1.016
1.457TrpSer: 1.457 ± 0.669
0.728TrpThr: 0.728 ± 0.347
0.728TrpVal: 0.728 ± 0.347
1.457TrpTrp: 1.457 ± 0.669
0.728TrpTyr: 0.728 ± 0.347
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.37TyrAla: 4.37 ± 0.719
0.0TyrCys: 0.0 ± 0.0
2.185TyrAsp: 2.185 ± 1.685
0.0TyrGlu: 0.0 ± 0.0
0.0TyrPhe: 0.0 ± 0.0
3.642TyrGly: 3.642 ± 0.372
2.913TyrHis: 2.913 ± 0.025
0.0TyrIle: 0.0 ± 0.0
0.0TyrLys: 0.0 ± 0.0
1.457TyrLeu: 1.457 ± 0.669
0.728TyrMet: 0.728 ± 1.016
2.185TyrAsn: 2.185 ± 1.041
1.457TyrPro: 1.457 ± 0.694
1.457TyrGln: 1.457 ± 0.694
1.457TyrArg: 1.457 ± 0.669
4.37TyrSer: 4.37 ± 2.081
2.185TyrThr: 2.185 ± 0.322
3.642TyrVal: 3.642 ± 0.372
1.457TyrTrp: 1.457 ± 0.694
0.728TyrTyr: 0.728 ± 0.347
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1374 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski