Amino acid dipepetide frequency for Paucilactobacillus wasatchensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.604AlaAla: 7.604 ± 0.157
0.328AlaCys: 0.328 ± 0.024
4.755AlaAsp: 4.755 ± 0.087
4.022AlaGlu: 4.022 ± 0.094
3.019AlaPhe: 3.019 ± 0.086
6.174AlaGly: 6.174 ± 0.125
1.624AlaHis: 1.624 ± 0.061
6.239AlaIle: 6.239 ± 0.11
5.48AlaLys: 5.48 ± 0.11
7.567AlaLeu: 7.567 ± 0.123
2.139AlaMet: 2.139 ± 0.072
3.942AlaAsn: 3.942 ± 0.091
2.42AlaPro: 2.42 ± 0.063
4.283AlaGln: 4.283 ± 0.09
2.769AlaArg: 2.769 ± 0.085
4.718AlaSer: 4.718 ± 0.121
5.572AlaThr: 5.572 ± 0.13
5.844AlaVal: 5.844 ± 0.111
0.643AlaTrp: 0.643 ± 0.038
2.338AlaTyr: 2.338 ± 0.072
0.0AlaXaa: 0.0 ± 0.0
Cys
0.382CysAla: 0.382 ± 0.027
0.045CysCys: 0.045 ± 0.01
0.274CysAsp: 0.274 ± 0.02
0.218CysGlu: 0.218 ± 0.02
0.224CysPhe: 0.224 ± 0.022
0.507CysGly: 0.507 ± 0.036
0.151CysHis: 0.151 ± 0.021
0.254CysIle: 0.254 ± 0.021
0.127CysLys: 0.127 ± 0.015
0.468CysLeu: 0.468 ± 0.033
0.093CysMet: 0.093 ± 0.014
0.159CysAsn: 0.159 ± 0.017
0.205CysPro: 0.205 ± 0.023
0.227CysGln: 0.227 ± 0.022
0.142CysArg: 0.142 ± 0.017
0.248CysSer: 0.248 ± 0.021
0.224CysThr: 0.224 ± 0.02
0.36CysVal: 0.36 ± 0.029
0.056CysTrp: 0.056 ± 0.01
0.173CysTyr: 0.173 ± 0.02
0.0CysXaa: 0.0 ± 0.0
Asp
4.071AspAla: 4.071 ± 0.098
0.252AspCys: 0.252 ± 0.025
3.558AspAsp: 3.558 ± 0.106
4.164AspGlu: 4.164 ± 0.098
2.609AspPhe: 2.609 ± 0.066
3.612AspGly: 3.612 ± 0.106
1.434AspHis: 1.434 ± 0.059
3.537AspIle: 3.537 ± 0.082
3.15AspLys: 3.15 ± 0.082
5.171AspLeu: 5.171 ± 0.105
1.32AspMet: 1.32 ± 0.049
2.661AspAsn: 2.661 ± 0.07
2.085AspPro: 2.085 ± 0.071
3.384AspGln: 3.384 ± 0.09
2.37AspArg: 2.37 ± 0.066
3.023AspSer: 3.023 ± 0.074
2.855AspThr: 2.855 ± 0.093
3.959AspVal: 3.959 ± 0.103
0.628AspTrp: 0.628 ± 0.033
2.277AspTyr: 2.277 ± 0.064
0.0AspXaa: 0.0 ± 0.0
Glu
3.823GluAla: 3.823 ± 0.101
0.173GluCys: 0.173 ± 0.017
2.575GluAsp: 2.575 ± 0.064
2.782GluGlu: 2.782 ± 0.101
2.256GluPhe: 2.256 ± 0.072
2.366GluGly: 2.366 ± 0.074
1.307GluHis: 1.307 ± 0.05
4.056GluIle: 4.056 ± 0.097
3.453GluLys: 3.453 ± 0.079
5.794GluLeu: 5.794 ± 0.124
1.775GluMet: 1.775 ± 0.055
2.739GluAsn: 2.739 ± 0.076
1.803GluPro: 1.803 ± 0.062
3.468GluGln: 3.468 ± 0.103
2.404GluArg: 2.404 ± 0.069
2.715GluSer: 2.715 ± 0.069
3.178GluThr: 3.178 ± 0.077
3.64GluVal: 3.64 ± 0.098
0.476GluTrp: 0.476 ± 0.027
1.727GluTyr: 1.727 ± 0.07
0.0GluXaa: 0.0 ± 0.0
Phe
3.455PheAla: 3.455 ± 0.077
0.254PheCys: 0.254 ± 0.02
3.002PheAsp: 3.002 ± 0.073
2.217PheGlu: 2.217 ± 0.067
1.969PhePhe: 1.969 ± 0.072
3.536PheGly: 3.536 ± 0.095
0.886PheHis: 0.886 ± 0.043
3.025PheIle: 3.025 ± 0.086
2.558PheLys: 2.558 ± 0.075
3.616PheLeu: 3.616 ± 0.102
1.134PheMet: 1.134 ± 0.049
2.253PheAsn: 2.253 ± 0.063
1.376PhePro: 1.376 ± 0.063
1.358PheGln: 1.358 ± 0.049
1.285PheArg: 1.285 ± 0.05
3.03PheSer: 3.03 ± 0.067
2.566PheThr: 2.566 ± 0.065
3.191PheVal: 3.191 ± 0.084
0.53PheTrp: 0.53 ± 0.031
1.537PheTyr: 1.537 ± 0.048
0.0PheXaa: 0.0 ± 0.0
Gly
5.147GlyAla: 5.147 ± 0.117
0.365GlyCys: 0.365 ± 0.031
3.521GlyAsp: 3.521 ± 0.079
3.2GlyGlu: 3.2 ± 0.08
3.069GlyPhe: 3.069 ± 0.092
4.548GlyGly: 4.548 ± 0.113
1.537GlyHis: 1.537 ± 0.052
5.473GlyIle: 5.473 ± 0.116
4.337GlyLys: 4.337 ± 0.105
6.646GlyLeu: 6.646 ± 0.118
1.965GlyMet: 1.965 ± 0.057
2.898GlyAsn: 2.898 ± 0.078
1.648GlyPro: 1.648 ± 0.064
3.081GlyGln: 3.081 ± 0.083
2.575GlyArg: 2.575 ± 0.066
4.043GlySer: 4.043 ± 0.086
4.459GlyThr: 4.459 ± 0.104
5.046GlyVal: 5.046 ± 0.109
0.75GlyTrp: 0.75 ± 0.034
2.709GlyTyr: 2.709 ± 0.072
0.0GlyXaa: 0.0 ± 0.0
His
1.572HisAla: 1.572 ± 0.057
0.132HisCys: 0.132 ± 0.018
1.249HisAsp: 1.249 ± 0.051
1.372HisGlu: 1.372 ± 0.059
1.113HisPhe: 1.113 ± 0.046
1.634HisGly: 1.634 ± 0.061
0.697HisHis: 0.697 ± 0.037
1.283HisIle: 1.283 ± 0.046
1.057HisLys: 1.057 ± 0.044
2.26HisLeu: 2.26 ± 0.073
0.477HisMet: 0.477 ± 0.031
0.942HisAsn: 0.942 ± 0.041
1.027HisPro: 1.027 ± 0.045
1.287HisGln: 1.287 ± 0.045
0.945HisArg: 0.945 ± 0.053
1.175HisSer: 1.175 ± 0.044
1.031HisThr: 1.031 ± 0.05
1.535HisVal: 1.535 ± 0.051
0.272HisTrp: 0.272 ± 0.025
0.867HisTyr: 0.867 ± 0.05
0.0HisXaa: 0.0 ± 0.0
Ile
6.29IleAla: 6.29 ± 0.125
0.496IleCys: 0.496 ± 0.033
4.673IleAsp: 4.673 ± 0.105
4.125IleGlu: 4.125 ± 0.091
3.058IlePhe: 3.058 ± 0.089
5.589IleGly: 5.589 ± 0.11
1.307IleHis: 1.307 ± 0.046
5.333IleIle: 5.333 ± 0.124
4.703IleLys: 4.703 ± 0.092
6.681IleLeu: 6.681 ± 0.141
1.874IleMet: 1.874 ± 0.069
3.86IleAsn: 3.86 ± 0.093
2.704IlePro: 2.704 ± 0.073
2.4IleGln: 2.4 ± 0.079
2.588IleArg: 2.588 ± 0.076
4.733IleSer: 4.733 ± 0.098
4.55IleThr: 4.55 ± 0.114
5.549IleVal: 5.549 ± 0.11
0.628IleTrp: 0.628 ± 0.037
2.254IleTyr: 2.254 ± 0.066
0.0IleXaa: 0.0 ± 0.0
Lys
4.214LysAla: 4.214 ± 0.097
0.131LysCys: 0.131 ± 0.017
2.842LysAsp: 2.842 ± 0.081
3.299LysGlu: 3.299 ± 0.093
2.131LysPhe: 2.131 ± 0.069
2.758LysGly: 2.758 ± 0.075
1.221LysHis: 1.221 ± 0.044
4.77LysIle: 4.77 ± 0.099
4.6LysLys: 4.6 ± 0.118
6.057LysLeu: 6.057 ± 0.122
2.29LysMet: 2.29 ± 0.062
3.377LysAsn: 3.377 ± 0.085
2.027LysPro: 2.027 ± 0.073
3.873LysGln: 3.873 ± 0.106
2.879LysArg: 2.879 ± 0.08
3.429LysSer: 3.429 ± 0.09
4.076LysThr: 4.076 ± 0.081
4.054LysVal: 4.054 ± 0.088
0.612LysTrp: 0.612 ± 0.034
2.355LysTyr: 2.355 ± 0.069
0.0LysXaa: 0.0 ± 0.0
Leu
8.798LeuAla: 8.798 ± 0.124
0.509LeuCys: 0.509 ± 0.031
5.225LeuAsp: 5.225 ± 0.111
4.324LeuGlu: 4.324 ± 0.098
4.142LeuPhe: 4.142 ± 0.102
6.599LeuGly: 6.599 ± 0.124
1.951LeuHis: 1.951 ± 0.06
7.744LeuIle: 7.744 ± 0.145
5.9LeuLys: 5.9 ± 0.115
9.385LeuLeu: 9.385 ± 0.178
2.614LeuMet: 2.614 ± 0.077
4.88LeuAsn: 4.88 ± 0.098
4.108LeuPro: 4.108 ± 0.087
4.306LeuGln: 4.306 ± 0.102
3.588LeuArg: 3.588 ± 0.089
6.372LeuSer: 6.372 ± 0.135
6.941LeuThr: 6.941 ± 0.123
7.155LeuVal: 7.155 ± 0.121
0.798LeuTrp: 0.798 ± 0.042
2.495LeuTyr: 2.495 ± 0.078
0.0LeuXaa: 0.0 ± 0.0
Met
2.458MetAla: 2.458 ± 0.075
0.117MetCys: 0.117 ± 0.015
1.445MetAsp: 1.445 ± 0.047
1.203MetGlu: 1.203 ± 0.051
1.054MetPhe: 1.054 ± 0.05
1.855MetGly: 1.855 ± 0.062
0.541MetHis: 0.541 ± 0.035
1.992MetIle: 1.992 ± 0.054
1.82MetLys: 1.82 ± 0.064
2.497MetLeu: 2.497 ± 0.064
0.774MetMet: 0.774 ± 0.041
1.417MetAsn: 1.417 ± 0.048
1.096MetPro: 1.096 ± 0.044
1.372MetGln: 1.372 ± 0.057
1.063MetArg: 1.063 ± 0.047
1.675MetSer: 1.675 ± 0.057
1.883MetThr: 1.883 ± 0.06
1.919MetVal: 1.919 ± 0.066
0.201MetTrp: 0.201 ± 0.019
0.673MetTyr: 0.673 ± 0.035
0.0MetXaa: 0.0 ± 0.0
Asn
3.655AsnAla: 3.655 ± 0.084
0.211AsnCys: 0.211 ± 0.023
2.79AsnAsp: 2.79 ± 0.085
2.978AsnGlu: 2.978 ± 0.076
2.102AsnPhe: 2.102 ± 0.058
3.467AsnGly: 3.467 ± 0.095
1.279AsnHis: 1.279 ± 0.054
3.146AsnIle: 3.146 ± 0.079
2.862AsnLys: 2.862 ± 0.075
4.505AsnLeu: 4.505 ± 0.107
1.251AsnMet: 1.251 ± 0.05
2.467AsnAsn: 2.467 ± 0.082
1.973AsnPro: 1.973 ± 0.061
2.887AsnGln: 2.887 ± 0.076
2.042AsnArg: 2.042 ± 0.065
2.929AsnSer: 2.929 ± 0.074
2.504AsnThr: 2.504 ± 0.072
3.375AsnVal: 3.375 ± 0.076
0.623AsnTrp: 0.623 ± 0.037
1.882AsnTyr: 1.882 ± 0.064
0.0AsnXaa: 0.0 ± 0.0
Pro
3.099ProAla: 3.099 ± 0.083
0.097ProCys: 0.097 ± 0.014
2.318ProAsp: 2.318 ± 0.072
2.333ProGlu: 2.333 ± 0.061
1.652ProPhe: 1.652 ± 0.053
2.193ProGly: 2.193 ± 0.069
0.737ProHis: 0.737 ± 0.037
2.676ProIle: 2.676 ± 0.075
2.051ProLys: 2.051 ± 0.064
3.222ProLeu: 3.222 ± 0.076
0.737ProMet: 0.737 ± 0.042
1.688ProAsn: 1.688 ± 0.054
0.58ProPro: 0.58 ± 0.037
1.714ProGln: 1.714 ± 0.054
1.07ProArg: 1.07 ± 0.042
1.945ProSer: 1.945 ± 0.068
2.564ProThr: 2.564 ± 0.069
2.887ProVal: 2.887 ± 0.076
0.343ProTrp: 0.343 ± 0.026
1.249ProTyr: 1.249 ± 0.053
0.0ProXaa: 0.0 ± 0.0
Gln
4.244GlnAla: 4.244 ± 0.097
0.144GlnCys: 0.144 ± 0.017
2.018GlnAsp: 2.018 ± 0.053
2.383GlnGlu: 2.383 ± 0.069
2.094GlnPhe: 2.094 ± 0.076
2.286GlnGly: 2.286 ± 0.067
1.253GlnHis: 1.253 ± 0.053
3.955GlnIle: 3.955 ± 0.105
2.806GlnLys: 2.806 ± 0.075
6.198GlnLeu: 6.198 ± 0.139
1.399GlnMet: 1.399 ± 0.055
2.309GlnAsn: 2.309 ± 0.065
1.799GlnPro: 1.799 ± 0.064
3.552GlnGln: 3.552 ± 0.136
2.355GlnArg: 2.355 ± 0.066
2.831GlnSer: 2.831 ± 0.076
3.427GlnThr: 3.427 ± 0.084
3.558GlnVal: 3.558 ± 0.086
0.502GlnTrp: 0.502 ± 0.031
1.688GlnTyr: 1.688 ± 0.055
0.0GlnXaa: 0.0 ± 0.0
Arg
2.75ArgAla: 2.75 ± 0.069
0.162ArgCys: 0.162 ± 0.017
2.144ArgAsp: 2.144 ± 0.067
2.34ArgGlu: 2.34 ± 0.068
1.867ArgPhe: 1.867 ± 0.06
2.424ArgGly: 2.424 ± 0.072
1.02ArgHis: 1.02 ± 0.042
2.592ArgIle: 2.592 ± 0.068
2.389ArgLys: 2.389 ± 0.065
3.938ArgLeu: 3.938 ± 0.088
1.029ArgMet: 1.029 ± 0.042
1.749ArgAsn: 1.749 ± 0.065
1.453ArgPro: 1.453 ± 0.049
2.452ArgGln: 2.452 ± 0.079
1.98ArgArg: 1.98 ± 0.063
1.98ArgSer: 1.98 ± 0.063
2.047ArgThr: 2.047 ± 0.065
2.747ArgVal: 2.747 ± 0.068
0.352ArgTrp: 0.352 ± 0.028
1.481ArgTyr: 1.481 ± 0.06
0.0ArgXaa: 0.0 ± 0.0
Ser
4.953SerAla: 4.953 ± 0.129
0.2SerCys: 0.2 ± 0.021
3.442SerAsp: 3.442 ± 0.087
2.987SerGlu: 2.987 ± 0.079
2.87SerPhe: 2.87 ± 0.077
4.548SerGly: 4.548 ± 0.094
1.281SerHis: 1.281 ± 0.047
4.231SerIle: 4.231 ± 0.092
3.39SerLys: 3.39 ± 0.095
5.861SerLeu: 5.861 ± 0.108
1.658SerMet: 1.658 ± 0.051
2.941SerAsn: 2.941 ± 0.079
1.766SerPro: 1.766 ± 0.054
2.944SerGln: 2.944 ± 0.088
2.206SerArg: 2.206 ± 0.062
4.591SerSer: 4.591 ± 0.238
3.636SerThr: 3.636 ± 0.105
4.488SerVal: 4.488 ± 0.095
0.632SerTrp: 0.632 ± 0.038
2.116SerTyr: 2.116 ± 0.066
0.0SerXaa: 0.0 ± 0.0
Thr
5.152ThrAla: 5.152 ± 0.122
0.248ThrCys: 0.248 ± 0.022
3.733ThrAsp: 3.733 ± 0.095
2.954ThrGlu: 2.954 ± 0.073
2.491ThrPhe: 2.491 ± 0.076
4.802ThrGly: 4.802 ± 0.11
1.248ThrHis: 1.248 ± 0.043
4.832ThrIle: 4.832 ± 0.1
4.311ThrLys: 4.311 ± 0.095
5.682ThrLeu: 5.682 ± 0.11
1.529ThrMet: 1.529 ± 0.056
3.334ThrAsn: 3.334 ± 0.081
2.754ThrPro: 2.754 ± 0.074
2.605ThrGln: 2.605 ± 0.079
1.995ThrArg: 1.995 ± 0.064
3.955ThrSer: 3.955 ± 0.109
4.591ThrThr: 4.591 ± 0.138
4.845ThrVal: 4.845 ± 0.105
0.574ThrTrp: 0.574 ± 0.034
1.96ThrTyr: 1.96 ± 0.066
0.0ThrXaa: 0.0 ± 0.0
Val
6.905ValAla: 6.905 ± 0.127
0.418ValCys: 0.418 ± 0.03
4.104ValAsp: 4.104 ± 0.092
3.536ValGlu: 3.536 ± 0.081
2.799ValPhe: 2.799 ± 0.074
5.137ValGly: 5.137 ± 0.116
1.227ValHis: 1.227 ± 0.045
5.581ValIle: 5.581 ± 0.106
4.177ValLys: 4.177 ± 0.097
7.006ValLeu: 7.006 ± 0.116
1.975ValMet: 1.975 ± 0.061
3.509ValAsn: 3.509 ± 0.089
2.681ValPro: 2.681 ± 0.072
2.598ValGln: 2.598 ± 0.073
2.585ValArg: 2.585 ± 0.068
4.735ValSer: 4.735 ± 0.102
5.288ValThr: 5.288 ± 0.111
5.736ValVal: 5.736 ± 0.106
0.643ValTrp: 0.643 ± 0.031
2.156ValTyr: 2.156 ± 0.06
0.0ValXaa: 0.0 ± 0.0
Trp
0.574TrpAla: 0.574 ± 0.034
0.041TrpCys: 0.041 ± 0.009
0.476TrpAsp: 0.476 ± 0.033
0.386TrpGlu: 0.386 ± 0.025
0.522TrpPhe: 0.522 ± 0.033
0.595TrpGly: 0.595 ± 0.03
0.319TrpHis: 0.319 ± 0.025
0.682TrpIle: 0.682 ± 0.039
0.418TrpLys: 0.418 ± 0.026
1.445TrpLeu: 1.445 ± 0.058
0.257TrpMet: 0.257 ± 0.021
0.427TrpAsn: 0.427 ± 0.028
0.324TrpPro: 0.324 ± 0.023
0.709TrpGln: 0.709 ± 0.036
0.494TrpArg: 0.494 ± 0.03
0.518TrpSer: 0.518 ± 0.027
0.485TrpThr: 0.485 ± 0.029
0.627TrpVal: 0.627 ± 0.033
0.188TrpTrp: 0.188 ± 0.017
0.332TrpTyr: 0.332 ± 0.027
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.338TyrAla: 2.338 ± 0.067
0.214TyrCys: 0.214 ± 0.019
1.975TyrAsp: 1.975 ± 0.069
1.688TyrGlu: 1.688 ± 0.057
1.734TyrPhe: 1.734 ± 0.056
2.387TyrGly: 2.387 ± 0.069
0.91TyrHis: 0.91 ± 0.043
1.995TyrIle: 1.995 ± 0.058
1.404TyrLys: 1.404 ± 0.057
3.834TyrLeu: 3.834 ± 0.088
0.763TyrMet: 0.763 ± 0.036
1.376TyrAsn: 1.376 ± 0.05
1.322TyrPro: 1.322 ± 0.049
2.301TyrGln: 2.301 ± 0.065
1.563TyrArg: 1.563 ± 0.061
2.098TyrSer: 2.098 ± 0.061
1.717TyrThr: 1.717 ± 0.061
2.282TyrVal: 2.282 ± 0.069
0.367TyrTrp: 0.367 ± 0.032
1.348TyrTyr: 1.348 ± 0.057
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1826 proteins (536271 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski