Amino acid dipepetide frequency for Monodelphis domestica (Gray short-tailed opossum)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.574AlaAla: 5.574 ± 0.035	1.212AlaCys: 1.212 ± 0.008	2.584AlaAsp: 2.584 ± 0.012	4.153AlaGlu: 4.153 ± 0.021	2.825AlaPhe: 2.825 ± 0.018	3.93AlaGly: 3.93 ± 0.022	1.401AlaHis: 1.401 ± 0.009	2.973AlaIle: 2.973 ± 0.012	3.375AlaLys: 3.375 ± 0.017	6.36AlaLeu: 6.36 ± 0.022	1.406AlaMet: 1.406 ± 0.009	2.072AlaAsn: 2.072 ± 0.01	3.485AlaPro: 3.485 ± 0.02	2.87AlaGln: 2.87 ± 0.017	3.052AlaArg: 3.052 ± 0.016	5.221AlaSer: 5.221 ± 0.024	3.341AlaThr: 3.341 ± 0.018	4.211AlaVal: 4.211 ± 0.017	0.713AlaTrp: 0.713 ± 0.007	1.454AlaTyr: 1.454 ± 0.009	0.0AlaXaa: 0.0 ± 0.0
Cys	1.098CysAla: 1.098 ± 0.009	0.628CysCys: 0.628 ± 0.012	0.997CysAsp: 0.997 ± 0.011	1.275CysGlu: 1.275 ± 0.014	0.879CysPhe: 0.879 ± 0.007	1.939CysGly: 1.939 ± 0.021	0.629CysHis: 0.629 ± 0.007	1.048CysIle: 1.048 ± 0.009	1.374CysLys: 1.374 ± 0.015	2.181CysLeu: 2.181 ± 0.014	0.422CysMet: 0.422 ± 0.005	0.994CysAsn: 0.994 ± 0.013	1.344CysPro: 1.344 ± 0.013	1.077CysGln: 1.077 ± 0.013	1.165CysArg: 1.165 ± 0.01	1.962CysSer: 1.962 ± 0.013	1.082CysThr: 1.082 ± 0.01	1.219CysVal: 1.219 ± 0.01	0.304CysTrp: 0.304 ± 0.004	0.586CysTyr: 0.586 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	2.565AspAla: 2.565 ± 0.012	1.023AspCys: 1.023 ± 0.009	2.555AspAsp: 2.555 ± 0.016	3.399AspGlu: 3.399 ± 0.018	2.146AspPhe: 2.146 ± 0.012	3.129AspGly: 3.129 ± 0.019	1.174AspHis: 1.174 ± 0.008	2.805AspIle: 2.805 ± 0.013	2.714AspLys: 2.714 ± 0.015	5.013AspLeu: 5.013 ± 0.016	1.139AspMet: 1.139 ± 0.008	1.842AspAsn: 1.842 ± 0.012	2.722AspPro: 2.722 ± 0.013	1.884AspGln: 1.884 ± 0.011	2.331AspArg: 2.331 ± 0.011	4.086AspSer: 4.086 ± 0.017	2.375AspThr: 2.375 ± 0.012	2.853AspVal: 2.853 ± 0.013	0.604AspTrp: 0.604 ± 0.007	1.487AspTyr: 1.487 ± 0.01	0.0AspXaa: 0.0 ± 0.0
Glu	4.605GluAla: 4.605 ± 0.021	1.806GluCys: 1.806 ± 0.025	4.232GluAsp: 4.232 ± 0.019	7.921GluGlu: 7.921 ± 0.041	2.086GluPhe: 2.086 ± 0.01	4.024GluGly: 4.024 ± 0.018	1.495GluHis: 1.495 ± 0.009	3.693GluIle: 3.693 ± 0.018	6.105GluLys: 6.105 ± 0.031	6.309GluLeu: 6.309 ± 0.028	1.778GluMet: 1.778 ± 0.009	3.474GluAsn: 3.474 ± 0.017	2.882GluPro: 2.882 ± 0.014	3.062GluGln: 3.062 ± 0.016	3.878GluArg: 3.878 ± 0.018	4.477GluSer: 4.477 ± 0.02	3.492GluThr: 3.492 ± 0.015	3.985GluVal: 3.985 ± 0.016	0.707GluTrp: 0.707 ± 0.006	1.638GluTyr: 1.638 ± 0.009	0.001GluXaa: 0.001 ± 0.0
Phe	1.935PheAla: 1.935 ± 0.012	0.977PheCys: 0.977 ± 0.007	1.767PheAsp: 1.767 ± 0.011	2.039PheGlu: 2.039 ± 0.011	1.809PhePhe: 1.809 ± 0.014	2.161PheGly: 2.161 ± 0.014	1.078PheHis: 1.078 ± 0.008	2.173PheIle: 2.173 ± 0.012	1.921PheLys: 1.921 ± 0.01	4.406PheLeu: 4.406 ± 0.023	0.793PheMet: 0.793 ± 0.008	1.482PheAsn: 1.482 ± 0.01	2.075PhePro: 2.075 ± 0.011	1.855PheGln: 1.855 ± 0.01	2.011PheArg: 2.011 ± 0.01	3.776PheSer: 3.776 ± 0.017	2.307PheThr: 2.307 ± 0.015	2.122PheVal: 2.122 ± 0.012	0.543PheTrp: 0.543 ± 0.005	1.317PheTyr: 1.317 ± 0.008	0.0PheXaa: 0.0 ± 0.0
Gly	3.806GlyAla: 3.806 ± 0.023	1.177GlyCys: 1.177 ± 0.009	2.935GlyAsp: 2.935 ± 0.014	4.29GlyGlu: 4.29 ± 0.024	2.38GlyPhe: 2.38 ± 0.016	4.713GlyGly: 4.713 ± 0.03	1.592GlyHis: 1.592 ± 0.01	2.952GlyIle: 2.952 ± 0.016	4.252GlyLys: 4.252 ± 0.024	5.455GlyLeu: 5.455 ± 0.022	1.319GlyMet: 1.319 ± 0.008	2.552GlyAsn: 2.552 ± 0.014	3.586GlyPro: 3.586 ± 0.03	2.622GlyGln: 2.622 ± 0.016	3.452GlyArg: 3.452 ± 0.016	5.53GlySer: 5.53 ± 0.026	3.457GlyThr: 3.457 ± 0.018	3.224GlyVal: 3.224 ± 0.014	0.778GlyTrp: 0.778 ± 0.008	1.721GlyTyr: 1.721 ± 0.014	0.001GlyXaa: 0.001 ± 0.0
His	1.183HisAla: 1.183 ± 0.009	0.734HisCys: 0.734 ± 0.008	0.882HisAsp: 0.882 ± 0.006	1.314HisGlu: 1.314 ± 0.008	1.094HisPhe: 1.094 ± 0.007	1.445HisGly: 1.445 ± 0.01	0.924HisHis: 0.924 ± 0.008	1.365HisIle: 1.365 ± 0.01	1.351HisLys: 1.351 ± 0.008	2.928HisLeu: 2.928 ± 0.014	0.603HisMet: 0.603 ± 0.005	0.924HisAsn: 0.924 ± 0.007	1.559HisPro: 1.559 ± 0.01	1.731HisGln: 1.731 ± 0.02	1.502HisArg: 1.502 ± 0.01	2.304HisSer: 2.304 ± 0.012	1.77HisThr: 1.77 ± 0.018	1.335HisVal: 1.335 ± 0.007	0.348HisTrp: 0.348 ± 0.004	0.809HisTyr: 0.809 ± 0.006	0.0HisXaa: 0.0 ± 0.0
Ile	2.697IleAla: 2.697 ± 0.014	1.197IleCys: 1.197 ± 0.009	2.307IleAsp: 2.307 ± 0.011	2.939IleGlu: 2.939 ± 0.015	2.14IlePhe: 2.14 ± 0.014	2.435IleGly: 2.435 ± 0.012	1.9IleHis: 1.9 ± 0.02	3.002IleIle: 3.002 ± 0.019	3.09IleLys: 3.09 ± 0.017	5.167IleLeu: 5.167 ± 0.019	1.129IleMet: 1.129 ± 0.009	2.249IleAsn: 2.249 ± 0.015	2.87IlePro: 2.87 ± 0.012	2.594IleGln: 2.594 ± 0.012	2.612IleArg: 2.612 ± 0.013	4.258IleSer: 4.258 ± 0.016	2.851IleThr: 2.851 ± 0.015	2.654IleVal: 2.654 ± 0.014	0.601IleTrp: 0.601 ± 0.005	1.643IleTyr: 1.643 ± 0.012	0.0IleXaa: 0.0 ± 0.0
Lys	4.117LysAla: 4.117 ± 0.018	1.214LysCys: 1.214 ± 0.01	3.288LysAsp: 3.288 ± 0.015	5.61LysGlu: 5.61 ± 0.029	1.848LysPhe: 1.848 ± 0.011	3.34LysGly: 3.34 ± 0.018	1.522LysHis: 1.522 ± 0.011	3.361LysIle: 3.361 ± 0.02	5.165LysLys: 5.165 ± 0.027	5.475LysLeu: 5.475 ± 0.021	1.553LysMet: 1.553 ± 0.008	2.774LysAsn: 2.774 ± 0.016	3.394LysPro: 3.394 ± 0.021	2.904LysGln: 2.904 ± 0.017	3.36LysArg: 3.36 ± 0.015	4.147LysSer: 4.147 ± 0.02	3.608LysThr: 3.608 ± 0.021	3.534LysVal: 3.534 ± 0.016	0.651LysTrp: 0.651 ± 0.006	1.667LysTyr: 1.667 ± 0.01	0.0LysXaa: 0.0 ± 0.0
Leu	6.348LeuAla: 6.348 ± 0.026	2.096LeuCys: 2.096 ± 0.014	4.666LeuAsp: 4.666 ± 0.018	7.153LeuGlu: 7.153 ± 0.033	3.63LeuPhe: 3.63 ± 0.016	5.629LeuGly: 5.629 ± 0.022	2.675LeuHis: 2.675 ± 0.013	4.396LeuIle: 4.396 ± 0.021	6.104LeuLys: 6.104 ± 0.022	10.369LeuLeu: 10.369 ± 0.035	2.087LeuMet: 2.087 ± 0.012	3.852LeuAsn: 3.852 ± 0.016	5.818LeuPro: 5.818 ± 0.025	5.553LeuGln: 5.553 ± 0.025	5.413LeuArg: 5.413 ± 0.021	8.201LeuSer: 8.201 ± 0.028	5.236LeuThr: 5.236 ± 0.019	5.252LeuVal: 5.252 ± 0.02	1.145LeuTrp: 1.145 ± 0.009	2.675LeuTyr: 2.675 ± 0.013	0.001LeuXaa: 0.001 ± 0.0
Met	1.788MetAla: 1.788 ± 0.01	0.395MetCys: 0.395 ± 0.005	1.308MetAsp: 1.308 ± 0.009	1.918MetGlu: 1.918 ± 0.01	0.772MetPhe: 0.772 ± 0.007	1.264MetGly: 1.264 ± 0.009	0.47MetHis: 0.47 ± 0.006	1.027MetIle: 1.027 ± 0.007	1.57MetLys: 1.57 ± 0.009	2.002MetLeu: 2.002 ± 0.012	0.611MetMet: 0.611 ± 0.006	1.016MetAsn: 1.016 ± 0.007	1.052MetPro: 1.052 ± 0.008	0.944MetGln: 0.944 ± 0.007	0.983MetArg: 0.983 ± 0.007	1.587MetSer: 1.587 ± 0.009	1.203MetThr: 1.203 ± 0.008	1.436MetVal: 1.436 ± 0.01	0.228MetTrp: 0.228 ± 0.003	0.638MetTyr: 0.638 ± 0.007	0.001MetXaa: 0.001 ± 0.0
Asn	2.035AsnAla: 2.035 ± 0.011	0.924AsnCys: 0.924 ± 0.009	1.662AsnAsp: 1.662 ± 0.011	2.589AsnGlu: 2.589 ± 0.014	1.659AsnPhe: 1.659 ± 0.01	2.621AsnGly: 2.621 ± 0.017	1.024AsnHis: 1.024 ± 0.007	2.508AsnIle: 2.508 ± 0.012	2.612AsnLys: 2.612 ± 0.016	4.027AsnLeu: 4.027 ± 0.015	1.01AsnMet: 1.01 ± 0.007	1.837AsnAsn: 1.837 ± 0.012	2.349AsnPro: 2.349 ± 0.013	1.909AsnGln: 1.909 ± 0.011	1.968AsnArg: 1.968 ± 0.011	3.508AsnSer: 3.508 ± 0.017	2.146AsnThr: 2.146 ± 0.011	2.274AsnVal: 2.274 ± 0.012	0.528AsnTrp: 0.528 ± 0.005	1.261AsnTyr: 1.261 ± 0.008	0.0AsnXaa: 0.0 ± 0.0
Pro	3.917ProAla: 3.917 ± 0.023	1.075ProCys: 1.075 ± 0.012	2.638ProAsp: 2.638 ± 0.014	4.144ProGlu: 4.144 ± 0.018	2.106ProPhe: 2.106 ± 0.011	4.513ProGly: 4.513 ± 0.043	1.371ProHis: 1.371 ± 0.008	2.137ProIle: 2.137 ± 0.011	2.854ProLys: 2.854 ± 0.015	5.1ProLeu: 5.1 ± 0.021	1.039ProMet: 1.039 ± 0.008	1.963ProAsn: 1.963 ± 0.012	5.468ProPro: 5.468 ± 0.047	2.671ProGln: 2.671 ± 0.017	3.042ProArg: 3.042 ± 0.017	5.511ProSer: 5.511 ± 0.027	2.934ProThr: 2.934 ± 0.014	3.444ProVal: 3.444 ± 0.018	0.638ProTrp: 0.638 ± 0.006	1.749ProTyr: 1.749 ± 0.018	0.001ProXaa: 0.001 ± 0.0
Gln	3.096GlnAla: 3.096 ± 0.019	1.219GlnCys: 1.219 ± 0.015	2.279GlnAsp: 2.279 ± 0.013	3.842GlnGlu: 3.842 ± 0.018	1.429GlnPhe: 1.429 ± 0.01	2.736GlnGly: 2.736 ± 0.016	1.314GlnHis: 1.314 ± 0.01	2.186GlnIle: 2.186 ± 0.012	3.119GlnLys: 3.119 ± 0.015	4.662GlnLeu: 4.662 ± 0.021	1.126GlnMet: 1.126 ± 0.009	2.063GlnAsn: 2.063 ± 0.012	2.601GlnPro: 2.601 ± 0.019	3.091GlnGln: 3.091 ± 0.035	3.113GlnArg: 3.113 ± 0.021	3.2GlnSer: 3.2 ± 0.015	2.391GlnThr: 2.391 ± 0.013	2.691GlnVal: 2.691 ± 0.014	0.54GlnTrp: 0.54 ± 0.006	1.166GlnTyr: 1.166 ± 0.008	0.0GlnXaa: 0.0 ± 0.0
Arg	3.294ArgAla: 3.294 ± 0.016	1.093ArgCys: 1.093 ± 0.01	2.614ArgAsp: 2.614 ± 0.012	3.882ArgGlu: 3.882 ± 0.02	1.806ArgPhe: 1.806 ± 0.011	3.272ArgGly: 3.272 ± 0.018	1.448ArgHis: 1.448 ± 0.01	2.919ArgIle: 2.919 ± 0.018	3.694ArgLys: 3.694 ± 0.016	4.992ArgLeu: 4.992 ± 0.017	1.167ArgMet: 1.167 ± 0.008	2.241ArgAsn: 2.241 ± 0.01	2.837ArgPro: 2.837 ± 0.017	2.456ArgGln: 2.456 ± 0.012	3.926ArgArg: 3.926 ± 0.021	4.131ArgSer: 4.131 ± 0.023	2.779ArgThr: 2.779 ± 0.016	2.84ArgVal: 2.84 ± 0.013	0.653ArgTrp: 0.653 ± 0.006	1.457ArgTyr: 1.457 ± 0.009	0.0ArgXaa: 0.0 ± 0.0
Ser	4.766SerAla: 4.766 ± 0.02	1.826SerCys: 1.826 ± 0.014	3.951SerAsp: 3.951 ± 0.017	5.088SerGlu: 5.088 ± 0.022	3.314SerPhe: 3.314 ± 0.016	5.408SerGly: 5.408 ± 0.024	2.188SerHis: 2.188 ± 0.011	3.72SerIle: 3.72 ± 0.019	4.339SerLys: 4.339 ± 0.02	8.537SerLeu: 8.537 ± 0.029	1.64SerMet: 1.64 ± 0.01	3.056SerAsn: 3.056 ± 0.018	5.819SerPro: 5.819 ± 0.034	3.919SerGln: 3.919 ± 0.02	4.297SerArg: 4.297 ± 0.025	9.583SerSer: 9.583 ± 0.043	4.608SerThr: 4.608 ± 0.025	4.696SerVal: 4.696 ± 0.018	1.065SerTrp: 1.065 ± 0.008	2.154SerTyr: 2.154 ± 0.011	0.001SerXaa: 0.001 ± 0.0
Thr	3.45ThrAla: 3.45 ± 0.015	1.326ThrCys: 1.326 ± 0.016	2.5ThrAsp: 2.5 ± 0.012	3.638ThrGlu: 3.638 ± 0.014	2.453ThrPhe: 2.453 ± 0.016	3.741ThrGly: 3.741 ± 0.019	1.285ThrHis: 1.285 ± 0.009	2.821ThrIle: 2.821 ± 0.014	2.938ThrLys: 2.938 ± 0.015	5.459ThrLeu: 5.459 ± 0.018	1.131ThrMet: 1.131 ± 0.008	1.942ThrAsn: 1.942 ± 0.01	3.333ThrPro: 3.333 ± 0.018	2.318ThrGln: 2.318 ± 0.014	2.415ThrArg: 2.415 ± 0.011	4.712ThrSer: 4.712 ± 0.024	3.02ThrThr: 3.02 ± 0.026	3.722ThrVal: 3.722 ± 0.019	0.727ThrTrp: 0.727 ± 0.008	1.472ThrTyr: 1.472 ± 0.01	0.0ThrXaa: 0.0 ± 0.0
Val	3.865ValAla: 3.865 ± 0.015	1.369ValCys: 1.369 ± 0.01	2.721ValAsp: 2.721 ± 0.015	3.632ValGlu: 3.632 ± 0.014	2.364ValPhe: 2.364 ± 0.013	3.101ValGly: 3.101 ± 0.013	1.557ValHis: 1.557 ± 0.012	3.118ValIle: 3.118 ± 0.015	3.394ValLys: 3.394 ± 0.016	5.854ValLeu: 5.854 ± 0.021	1.307ValMet: 1.307 ± 0.009	2.3ValAsn: 2.3 ± 0.011	3.291ValPro: 3.291 ± 0.014	2.567ValGln: 2.567 ± 0.012	2.705ValArg: 2.705 ± 0.013	4.649ValSer: 4.649 ± 0.017	3.607ValThr: 3.607 ± 0.016	3.652ValVal: 3.652 ± 0.016	0.684ValTrp: 0.684 ± 0.007	1.604ValTyr: 1.604 ± 0.009	0.001ValXaa: 0.001 ± 0.0
Trp	0.721TrpAla: 0.721 ± 0.006	0.236TrpCys: 0.236 ± 0.003	0.643TrpAsp: 0.643 ± 0.006	0.849TrpGlu: 0.849 ± 0.007	0.467TrpPhe: 0.467 ± 0.005	0.722TrpGly: 0.722 ± 0.009	0.29TrpHis: 0.29 ± 0.004	0.619TrpIle: 0.619 ± 0.006	0.903TrpLys: 0.903 ± 0.007	1.194TrpLeu: 1.194 ± 0.009	0.314TrpMet: 0.314 ± 0.005	0.631TrpAsn: 0.631 ± 0.006	0.478TrpPro: 0.478 ± 0.005	0.499TrpGln: 0.499 ± 0.005	0.724TrpArg: 0.724 ± 0.006	0.868TrpSer: 0.868 ± 0.008	0.646TrpThr: 0.646 ± 0.007	0.651TrpVal: 0.651 ± 0.006	0.191TrpTrp: 0.191 ± 0.003	0.368TrpTyr: 0.368 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.351TyrAla: 1.351 ± 0.009	0.675TyrCys: 0.675 ± 0.006	1.317TyrAsp: 1.317 ± 0.009	1.974TyrGlu: 1.974 ± 0.014	1.339TyrPhe: 1.339 ± 0.009	1.671TyrGly: 1.671 ± 0.011	0.768TyrHis: 0.768 ± 0.007	1.514TyrIle: 1.514 ± 0.01	1.659TyrLys: 1.659 ± 0.012	2.806TyrLeu: 2.806 ± 0.015	0.641TyrMet: 0.641 ± 0.006	1.187TyrAsn: 1.187 ± 0.008	1.351TyrPro: 1.351 ± 0.009	1.338TyrGln: 1.338 ± 0.009	1.549TyrArg: 1.549 ± 0.01	2.262TyrSer: 2.262 ± 0.012	1.549TyrThr: 1.549 ± 0.01	1.547TyrVal: 1.547 ± 0.01	0.367TyrTrp: 0.367 ± 0.005	0.986TyrTyr: 0.986 ± 0.008	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.001XaaMet: 0.001 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.524XaaXaa: 0.524 ± 0.11

Statistics based on 36221 proteins (22459468 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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