Amino acid dipepetide frequency for Lonsdalea quercina

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.304AlaAla: 10.304 ± 0.137	1.077AlaCys: 1.077 ± 0.03	5.214AlaAsp: 5.214 ± 0.083	5.983AlaGlu: 5.983 ± 0.081	3.412AlaPhe: 3.412 ± 0.059	7.397AlaGly: 7.397 ± 0.1	1.842AlaHis: 1.842 ± 0.041	5.586AlaIle: 5.586 ± 0.086	3.454AlaLys: 3.454 ± 0.07	12.421AlaLeu: 12.421 ± 0.137	2.778AlaMet: 2.778 ± 0.062	2.909AlaAsn: 2.909 ± 0.058	3.914AlaPro: 3.914 ± 0.065	4.516AlaGln: 4.516 ± 0.076	5.67AlaArg: 5.67 ± 0.082	5.774AlaSer: 5.774 ± 0.083	4.697AlaThr: 4.697 ± 0.061	6.812AlaVal: 6.812 ± 0.09	1.225AlaTrp: 1.225 ± 0.034	2.312AlaTyr: 2.312 ± 0.053	0.0AlaXaa: 0.0 ± 0.0
Cys	0.932CysAla: 0.932 ± 0.03	0.177CysCys: 0.177 ± 0.015	0.591CysAsp: 0.591 ± 0.023	0.572CysGlu: 0.572 ± 0.024	0.417CysPhe: 0.417 ± 0.02	1.073CysGly: 1.073 ± 0.031	0.348CysHis: 0.348 ± 0.019	0.516CysIle: 0.516 ± 0.025	0.256CysLys: 0.256 ± 0.016	1.085CysLeu: 1.085 ± 0.035	0.221CysMet: 0.221 ± 0.017	0.291CysAsn: 0.291 ± 0.018	0.489CysPro: 0.489 ± 0.023	0.454CysGln: 0.454 ± 0.022	0.73CysArg: 0.73 ± 0.029	0.647CysSer: 0.647 ± 0.023	0.457CysThr: 0.457 ± 0.021	0.745CysVal: 0.745 ± 0.027	0.171CysTrp: 0.171 ± 0.012	0.354CysTyr: 0.354 ± 0.02	0.0CysXaa: 0.0 ± 0.0
Asp	5.334AspAla: 5.334 ± 0.078	0.516AspCys: 0.516 ± 0.019	3.162AspAsp: 3.162 ± 0.064	3.537AspGlu: 3.537 ± 0.064	2.025AspPhe: 2.025 ± 0.049	3.975AspGly: 3.975 ± 0.072	1.082AspHis: 1.082 ± 0.034	3.575AspIle: 3.575 ± 0.062	2.239AspLys: 2.239 ± 0.05	4.762AspLeu: 4.762 ± 0.081	1.362AspMet: 1.362 ± 0.034	2.14AspAsn: 2.14 ± 0.048	2.338AspPro: 2.338 ± 0.05	1.723AspGln: 1.723 ± 0.041	3.102AspArg: 3.102 ± 0.059	3.051AspSer: 3.051 ± 0.056	2.68AspThr: 2.68 ± 0.065	4.144AspVal: 4.144 ± 0.071	0.82AspTrp: 0.82 ± 0.026	1.877AspTyr: 1.877 ± 0.043	0.001AspXaa: 0.001 ± 0.001
Glu	5.399GluAla: 5.399 ± 0.082	0.489GluCys: 0.489 ± 0.024	2.496GluAsp: 2.496 ± 0.053	3.159GluGlu: 3.159 ± 0.072	1.777GluPhe: 1.777 ± 0.043	3.591GluGly: 3.591 ± 0.052	1.466GluHis: 1.466 ± 0.039	3.078GluIle: 3.078 ± 0.063	2.877GluLys: 2.877 ± 0.06	5.916GluLeu: 5.916 ± 0.077	1.651GluMet: 1.651 ± 0.042	2.148GluAsn: 2.148 ± 0.048	2.172GluPro: 2.172 ± 0.039	3.519GluGln: 3.519 ± 0.062	4.115GluArg: 4.115 ± 0.069	3.083GluSer: 3.083 ± 0.059	2.984GluThr: 2.984 ± 0.049	3.712GluVal: 3.712 ± 0.071	0.721GluTrp: 0.721 ± 0.028	1.382GluTyr: 1.382 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	3.283PheAla: 3.283 ± 0.057	0.517PheCys: 0.517 ± 0.024	2.327PheAsp: 2.327 ± 0.045	1.615PheGlu: 1.615 ± 0.04	1.567PhePhe: 1.567 ± 0.044	3.002PheGly: 3.002 ± 0.054	0.823PheHis: 0.823 ± 0.028	2.397PheIle: 2.397 ± 0.054	1.188PheLys: 1.188 ± 0.035	3.162PheLeu: 3.162 ± 0.063	0.91PheMet: 0.91 ± 0.031	1.613PheAsn: 1.613 ± 0.042	1.568PhePro: 1.568 ± 0.038	1.22PheGln: 1.22 ± 0.036	1.948PheArg: 1.948 ± 0.044	3.177PheSer: 3.177 ± 0.059	2.175PheThr: 2.175 ± 0.049	2.355PheVal: 2.355 ± 0.055	0.54PheTrp: 0.54 ± 0.026	1.246PheTyr: 1.246 ± 0.042	0.0PheXaa: 0.0 ± 0.0
Gly	6.158GlyAla: 6.158 ± 0.092	0.986GlyCys: 0.986 ± 0.032	3.916GlyAsp: 3.916 ± 0.078	4.611GlyGlu: 4.611 ± 0.069	3.023GlyPhe: 3.023 ± 0.058	5.298GlyGly: 5.298 ± 0.092	1.708GlyHis: 1.708 ± 0.043	4.782GlyIle: 4.782 ± 0.07	3.658GlyLys: 3.658 ± 0.063	7.573GlyLeu: 7.573 ± 0.106	2.221GlyMet: 2.221 ± 0.046	2.658GlyAsn: 2.658 ± 0.075	2.1GlyPro: 2.1 ± 0.048	3.122GlyGln: 3.122 ± 0.06	4.265GlyArg: 4.265 ± 0.07	4.221GlySer: 4.221 ± 0.078	3.586GlyThr: 3.586 ± 0.069	5.672GlyVal: 5.672 ± 0.081	1.215GlyTrp: 1.215 ± 0.034	2.572GlyTyr: 2.572 ± 0.056	0.0GlyXaa: 0.0 ± 0.0
His	2.031HisAla: 2.031 ± 0.048	0.333HisCys: 0.333 ± 0.018	1.336HisAsp: 1.336 ± 0.035	1.078HisGlu: 1.078 ± 0.033	1.046HisPhe: 1.046 ± 0.035	1.789HisGly: 1.789 ± 0.045	0.82HisHis: 0.82 ± 0.033	1.314HisIle: 1.314 ± 0.037	0.671HisLys: 0.671 ± 0.026	2.4HisLeu: 2.4 ± 0.053	0.506HisMet: 0.506 ± 0.021	0.751HisAsn: 0.751 ± 0.027	1.425HisPro: 1.425 ± 0.042	1.392HisGln: 1.392 ± 0.036	1.462HisArg: 1.462 ± 0.039	1.324HisSer: 1.324 ± 0.037	1.119HisThr: 1.119 ± 0.032	1.331HisVal: 1.331 ± 0.038	0.449HisTrp: 0.449 ± 0.021	0.889HisTyr: 0.889 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	6.31IleAla: 6.31 ± 0.101	0.594IleCys: 0.594 ± 0.025	3.498IleAsp: 3.498 ± 0.063	3.236IleGlu: 3.236 ± 0.061	1.899IlePhe: 1.899 ± 0.049	4.531IleGly: 4.531 ± 0.072	1.238IleHis: 1.238 ± 0.038	3.002IleIle: 3.002 ± 0.065	2.116IleLys: 2.116 ± 0.049	4.71IleLeu: 4.71 ± 0.075	1.211IleMet: 1.211 ± 0.039	2.421IleAsn: 2.421 ± 0.05	2.681IlePro: 2.681 ± 0.052	1.963IleGln: 1.963 ± 0.041	3.124IleArg: 3.124 ± 0.055	3.726IleSer: 3.726 ± 0.058	3.266IleThr: 3.266 ± 0.054	3.951IleVal: 3.951 ± 0.069	0.601IleTrp: 0.601 ± 0.026	1.45IleTyr: 1.45 ± 0.041	0.0IleXaa: 0.0 ± 0.0
Lys	3.799LysAla: 3.799 ± 0.071	0.226LysCys: 0.226 ± 0.016	1.93LysAsp: 1.93 ± 0.043	2.131LysGlu: 2.131 ± 0.048	0.975LysPhe: 0.975 ± 0.034	2.65LysGly: 2.65 ± 0.051	0.797LysHis: 0.797 ± 0.031	2.082LysIle: 2.082 ± 0.043	1.905LysLys: 1.905 ± 0.049	3.803LysLeu: 3.803 ± 0.06	1.049LysMet: 1.049 ± 0.03	1.507LysAsn: 1.507 ± 0.039	1.929LysPro: 1.929 ± 0.047	1.949LysGln: 1.949 ± 0.046	2.44LysArg: 2.44 ± 0.054	2.26LysSer: 2.26 ± 0.047	2.479LysThr: 2.479 ± 0.05	2.692LysVal: 2.692 ± 0.06	0.356LysTrp: 0.356 ± 0.016	0.913LysTyr: 0.913 ± 0.035	0.0LysXaa: 0.0 ± 0.0
Leu	11.394LeuAla: 11.394 ± 0.132	1.31LeuCys: 1.31 ± 0.035	5.756LeuAsp: 5.756 ± 0.102	5.455LeuGlu: 5.455 ± 0.083	4.172LeuPhe: 4.172 ± 0.065	7.533LeuGly: 7.533 ± 0.101	2.43LeuHis: 2.43 ± 0.05	5.772LeuIle: 5.772 ± 0.093	4.234LeuLys: 4.234 ± 0.064	12.607LeuLeu: 12.607 ± 0.162	2.983LeuMet: 2.983 ± 0.064	4.197LeuAsn: 4.197 ± 0.071	6.082LeuPro: 6.082 ± 0.083	4.49LeuGln: 4.49 ± 0.09	6.738LeuArg: 6.738 ± 0.094	8.179LeuSer: 8.179 ± 0.093	6.772LeuThr: 6.772 ± 0.099	7.075LeuVal: 7.075 ± 0.087	1.402LeuTrp: 1.402 ± 0.045	2.662LeuTyr: 2.662 ± 0.054	0.0LeuXaa: 0.0 ± 0.0
Met	2.684MetAla: 2.684 ± 0.051	0.215MetCys: 0.215 ± 0.014	1.182MetAsp: 1.182 ± 0.032	1.236MetGlu: 1.236 ± 0.033	0.791MetPhe: 0.791 ± 0.029	1.762MetGly: 1.762 ± 0.04	0.5MetHis: 0.5 ± 0.021	1.362MetIle: 1.362 ± 0.036	1.241MetLys: 1.241 ± 0.036	3.146MetLeu: 3.146 ± 0.066	0.857MetMet: 0.857 ± 0.032	1.017MetAsn: 1.017 ± 0.028	1.312MetPro: 1.312 ± 0.034	1.156MetGln: 1.156 ± 0.035	1.458MetArg: 1.458 ± 0.036	1.858MetSer: 1.858 ± 0.036	1.841MetThr: 1.841 ± 0.042	1.892MetVal: 1.892 ± 0.049	0.199MetTrp: 0.199 ± 0.014	0.488MetTyr: 0.488 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	3.546AsnAla: 3.546 ± 0.052	0.281AsnCys: 0.281 ± 0.018	1.957AsnAsp: 1.957 ± 0.049	1.808AsnGlu: 1.808 ± 0.044	1.181AsnPhe: 1.181 ± 0.036	2.879AsnGly: 2.879 ± 0.058	0.789AsnHis: 0.789 ± 0.027	2.114AsnIle: 2.114 ± 0.048	1.389AsnLys: 1.389 ± 0.039	3.409AsnLeu: 3.409 ± 0.064	0.802AsnMet: 0.802 ± 0.03	1.407AsnAsn: 1.407 ± 0.049	2.036AsnPro: 2.036 ± 0.046	1.669AsnGln: 1.669 ± 0.043	2.041AsnArg: 2.041 ± 0.041	1.889AsnSer: 1.889 ± 0.046	1.961AsnThr: 1.961 ± 0.057	2.613AsnVal: 2.613 ± 0.057	0.464AsnTrp: 0.464 ± 0.024	1.054AsnTyr: 1.054 ± 0.03	0.0AsnXaa: 0.0 ± 0.0
Pro	4.642ProAla: 4.642 ± 0.07	0.38ProCys: 0.38 ± 0.02	2.843ProAsp: 2.843 ± 0.054	3.399ProGlu: 3.399 ± 0.063	1.845ProPhe: 1.845 ± 0.049	3.333ProGly: 3.333 ± 0.061	1.136ProHis: 1.136 ± 0.035	2.027ProIle: 2.027 ± 0.05	1.433ProLys: 1.433 ± 0.039	5.44ProLeu: 5.44 ± 0.079	1.104ProMet: 1.104 ± 0.033	1.368ProAsn: 1.368 ± 0.034	1.892ProPro: 1.892 ± 0.044	2.357ProGln: 2.357 ± 0.052	2.234ProArg: 2.234 ± 0.041	2.696ProSer: 2.696 ± 0.053	2.44ProThr: 2.44 ± 0.054	3.704ProVal: 3.704 ± 0.067	0.661ProTrp: 0.661 ± 0.025	1.28ProTyr: 1.28 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	4.911GlnAla: 4.911 ± 0.084	0.395GlnCys: 0.395 ± 0.023	2.16GlnAsp: 2.16 ± 0.049	2.416GlnGlu: 2.416 ± 0.057	1.425GlnPhe: 1.425 ± 0.038	3.261GlnGly: 3.261 ± 0.066	1.306GlnHis: 1.306 ± 0.039	2.212GlnIle: 2.212 ± 0.044	1.625GlnLys: 1.625 ± 0.043	5.409GlnLeu: 5.409 ± 0.089	1.153GlnMet: 1.153 ± 0.029	1.45GlnAsn: 1.45 ± 0.041	2.422GlnPro: 2.422 ± 0.059	3.551GlnGln: 3.551 ± 0.09	3.638GlnArg: 3.638 ± 0.064	2.623GlnSer: 2.623 ± 0.053	2.354GlnThr: 2.354 ± 0.051	3.252GlnVal: 3.252 ± 0.062	0.679GlnTrp: 0.679 ± 0.026	1.123GlnTyr: 1.123 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	4.848ArgAla: 4.848 ± 0.07	0.66ArgCys: 0.66 ± 0.027	3.235ArgAsp: 3.235 ± 0.058	3.813ArgGlu: 3.813 ± 0.065	2.626ArgPhe: 2.626 ± 0.059	3.626ArgGly: 3.626 ± 0.066	1.858ArgHis: 1.858 ± 0.043	3.585ArgIle: 3.585 ± 0.064	2.163ArgLys: 2.163 ± 0.046	7.254ArgLeu: 7.254 ± 0.105	1.646ArgMet: 1.646 ± 0.039	1.959ArgAsn: 1.959 ± 0.042	2.478ArgPro: 2.478 ± 0.052	3.672ArgGln: 3.672 ± 0.076	4.266ArgArg: 4.266 ± 0.075	3.054ArgSer: 3.054 ± 0.052	2.678ArgThr: 2.678 ± 0.053	4.17ArgVal: 4.17 ± 0.067	1.106ArgTrp: 1.106 ± 0.039	2.37ArgTyr: 2.37 ± 0.045	0.0ArgXaa: 0.0 ± 0.0
Ser	6.22SerAla: 6.22 ± 0.093	0.609SerCys: 0.609 ± 0.025	3.249SerAsp: 3.249 ± 0.05	3.252SerGlu: 3.252 ± 0.057	2.277SerPhe: 2.277 ± 0.057	5.45SerGly: 5.45 ± 0.084	1.614SerHis: 1.614 ± 0.036	2.999SerIle: 2.999 ± 0.062	1.899SerLys: 1.899 ± 0.053	7.441SerLeu: 7.441 ± 0.1	1.535SerMet: 1.535 ± 0.038	1.905SerAsn: 1.905 ± 0.048	2.93SerPro: 2.93 ± 0.051	2.929SerGln: 2.929 ± 0.06	3.707SerArg: 3.707 ± 0.061	4.056SerSer: 4.056 ± 0.105	3.155SerThr: 3.155 ± 0.059	4.427SerVal: 4.427 ± 0.073	0.921SerTrp: 0.921 ± 0.028	1.728SerTyr: 1.728 ± 0.042	0.0SerXaa: 0.0 ± 0.0
Thr	5.287ThrAla: 5.287 ± 0.09	0.463ThrCys: 0.463 ± 0.019	2.614ThrAsp: 2.614 ± 0.056	2.734ThrGlu: 2.734 ± 0.051	1.973ThrPhe: 1.973 ± 0.039	4.221ThrGly: 4.221 ± 0.083	1.3ThrHis: 1.3 ± 0.045	2.725ThrIle: 2.725 ± 0.057	1.342ThrLys: 1.342 ± 0.038	7.802ThrLeu: 7.802 ± 0.101	1.075ThrMet: 1.075 ± 0.035	1.443ThrAsn: 1.443 ± 0.038	3.343ThrPro: 3.343 ± 0.055	2.45ThrGln: 2.45 ± 0.052	3.049ThrArg: 3.049 ± 0.056	3.162ThrSer: 3.162 ± 0.055	2.953ThrThr: 2.953 ± 0.082	4.082ThrVal: 4.082 ± 0.092	0.64ThrTrp: 0.64 ± 0.028	1.26ThrTyr: 1.26 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	6.871ValAla: 6.871 ± 0.091	0.76ValCys: 0.76 ± 0.032	3.829ValAsp: 3.829 ± 0.069	3.96ValGlu: 3.96 ± 0.073	2.49ValPhe: 2.49 ± 0.051	4.977ValGly: 4.977 ± 0.079	1.239ValHis: 1.239 ± 0.031	4.426ValIle: 4.426 ± 0.072	2.907ValLys: 2.907 ± 0.063	7.403ValLeu: 7.403 ± 0.089	2.163ValMet: 2.163 ± 0.048	2.751ValAsn: 2.751 ± 0.051	3.034ValPro: 3.034 ± 0.059	2.443ValGln: 2.443 ± 0.055	3.881ValArg: 3.881 ± 0.057	4.995ValSer: 4.995 ± 0.083	4.446ValThr: 4.446 ± 0.096	5.604ValVal: 5.604 ± 0.074	0.896ValTrp: 0.896 ± 0.03	1.761ValTyr: 1.761 ± 0.046	0.0ValXaa: 0.0 ± 0.0
Trp	0.916TrpAla: 0.916 ± 0.033	0.167TrpCys: 0.167 ± 0.013	0.58TrpAsp: 0.58 ± 0.027	0.556TrpGlu: 0.556 ± 0.022	0.576TrpPhe: 0.576 ± 0.024	0.853TrpGly: 0.853 ± 0.033	0.386TrpHis: 0.386 ± 0.019	0.607TrpIle: 0.607 ± 0.026	0.467TrpLys: 0.467 ± 0.02	2.182TrpLeu: 2.182 ± 0.053	0.38TrpMet: 0.38 ± 0.019	0.437TrpAsn: 0.437 ± 0.022	0.624TrpPro: 0.624 ± 0.025	1.057TrpGln: 1.057 ± 0.036	1.134TrpArg: 1.134 ± 0.04	0.852TrpSer: 0.852 ± 0.033	0.484TrpThr: 0.484 ± 0.021	0.879TrpVal: 0.879 ± 0.03	0.23TrpTrp: 0.23 ± 0.016	0.364TrpTyr: 0.364 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.431TyrAla: 2.431 ± 0.055	0.37TyrCys: 0.37 ± 0.019	1.568TyrAsp: 1.568 ± 0.048	1.184TyrGlu: 1.184 ± 0.035	1.133TyrPhe: 1.133 ± 0.036	2.144TyrGly: 2.144 ± 0.057	0.786TyrHis: 0.786 ± 0.028	1.366TyrIle: 1.366 ± 0.037	0.81TyrLys: 0.81 ± 0.029	3.318TyrLeu: 3.318 ± 0.059	0.589TyrMet: 0.589 ± 0.025	0.916TyrAsn: 0.916 ± 0.034	1.444TyrPro: 1.444 ± 0.037	1.734TyrGln: 1.734 ± 0.043	2.064TyrArg: 2.064 ± 0.044	1.673TyrSer: 1.673 ± 0.048	1.393TyrThr: 1.393 ± 0.038	1.727TyrVal: 1.727 ± 0.043	0.435TyrTrp: 0.435 ± 0.019	0.901TyrTyr: 0.901 ± 0.032	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.001	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.003XaaXaa: 0.003 ± 0.003

Statistics based on 3284 proteins (1066459 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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