Amino acid dipepetide frequency for Trichomonas vaginalis virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.746AlaAla: 4.746 ± 2.503
2.034AlaCys: 2.034 ± 0.53
4.746AlaAsp: 4.746 ± 0.605
2.034AlaGlu: 2.034 ± 0.53
1.356AlaPhe: 1.356 ± 0.037
1.356AlaGly: 1.356 ± 0.037
3.39AlaHis: 3.39 ± 1.33
6.78AlaIle: 6.78 ± 0.762
3.39AlaLys: 3.39 ± 0.381
4.746AlaLeu: 4.746 ± 0.605
2.034AlaMet: 2.034 ± 1.479
5.424AlaAsn: 5.424 ± 1.749
6.78AlaPro: 6.78 ± 3.033
2.034AlaGln: 2.034 ± 1.479
4.068AlaArg: 4.068 ± 0.837
3.39AlaSer: 3.39 ± 0.568
8.136AlaThr: 8.136 ± 1.173
2.712AlaVal: 2.712 ± 0.075
0.0AlaTrp: 0.0 ± 0.0
3.39AlaTyr: 3.39 ± 0.568
0.0AlaXaa: 0.0 ± 0.0
Cys
2.034CysAla: 2.034 ± 0.53
0.678CysCys: 0.678 ± 0.493
0.678CysAsp: 0.678 ± 0.456
0.0CysGlu: 0.0 ± 0.0
1.356CysPhe: 1.356 ± 0.986
3.39CysGly: 3.39 ± 0.381
0.678CysHis: 0.678 ± 0.493
0.0CysIle: 0.0 ± 0.0
0.678CysLys: 0.678 ± 0.493
2.712CysLeu: 2.712 ± 0.874
0.678CysMet: 0.678 ± 0.456
0.0CysAsn: 0.0 ± 0.0
1.356CysPro: 1.356 ± 0.912
0.678CysGln: 0.678 ± 0.493
1.356CysArg: 1.356 ± 0.912
0.678CysSer: 0.678 ± 0.456
0.0CysThr: 0.0 ± 0.0
1.356CysVal: 1.356 ± 0.037
0.0CysTrp: 0.0 ± 0.0
1.356CysTyr: 1.356 ± 0.912
0.0CysXaa: 0.0 ± 0.0
Asp
5.424AspAla: 5.424 ± 0.149
0.678AspCys: 0.678 ± 0.493
2.712AspAsp: 2.712 ± 1.024
4.068AspGlu: 4.068 ± 2.01
2.712AspPhe: 2.712 ± 0.874
2.712AspGly: 2.712 ± 1.973
2.034AspHis: 2.034 ± 1.479
4.068AspIle: 4.068 ± 0.112
0.678AspLys: 0.678 ± 0.456
5.424AspLeu: 5.424 ± 2.698
0.678AspMet: 0.678 ± 0.456
4.746AspAsn: 4.746 ± 0.344
3.39AspPro: 3.39 ± 0.381
1.356AspGln: 1.356 ± 0.037
1.356AspArg: 1.356 ± 0.037
3.39AspSer: 3.39 ± 1.517
4.746AspThr: 4.746 ± 0.344
3.39AspVal: 3.39 ± 1.33
0.0AspTrp: 0.0 ± 0.0
3.39AspTyr: 3.39 ± 1.33
0.0AspXaa: 0.0 ± 0.0
Glu
1.356GluAla: 1.356 ± 0.912
0.0GluCys: 0.0 ± 0.0
0.0GluAsp: 0.0 ± 0.0
1.356GluGlu: 1.356 ± 0.037
2.712GluPhe: 2.712 ± 0.075
1.356GluGly: 1.356 ± 0.986
0.678GluHis: 0.678 ± 0.456
2.712GluIle: 2.712 ± 0.075
0.678GluLys: 0.678 ± 0.456
4.068GluLeu: 4.068 ± 0.112
0.678GluMet: 0.678 ± 0.78
1.356GluAsn: 1.356 ± 0.912
0.678GluPro: 0.678 ± 0.493
1.356GluGln: 1.356 ± 0.037
2.034GluArg: 2.034 ± 0.544
2.712GluSer: 2.712 ± 0.874
2.712GluThr: 2.712 ± 1.973
3.39GluVal: 3.39 ± 1.33
1.356GluTrp: 1.356 ± 0.037
1.356GluTyr: 1.356 ± 0.037
0.0GluXaa: 0.0 ± 0.0
Phe
4.068PheAla: 4.068 ± 0.112
0.0PheCys: 0.0 ± 0.0
1.356PheAsp: 1.356 ± 0.912
0.678PheGlu: 0.678 ± 0.493
0.0PhePhe: 0.0 ± 0.0
4.068PheGly: 4.068 ± 1.061
1.356PheHis: 1.356 ± 0.037
2.712PheIle: 2.712 ± 0.075
1.356PheLys: 1.356 ± 0.037
4.746PheLeu: 4.746 ± 2.242
0.0PheMet: 0.0 ± 0.0
2.712PheAsn: 2.712 ± 0.075
2.034PhePro: 2.034 ± 1.367
2.712PheGln: 2.712 ± 1.024
1.356PheArg: 1.356 ± 0.986
3.39PheSer: 3.39 ± 0.568
2.034PheThr: 2.034 ± 0.53
4.068PheVal: 4.068 ± 2.01
0.0PheTrp: 0.0 ± 0.0
2.712PheTyr: 2.712 ± 1.024
0.0PheXaa: 0.0 ± 0.0
Gly
3.39GlyAla: 3.39 ± 1.517
0.678GlyCys: 0.678 ± 0.456
2.712GlyAsp: 2.712 ± 0.075
1.356GlyGlu: 1.356 ± 0.037
2.712GlyPhe: 2.712 ± 1.973
2.034GlyGly: 2.034 ± 0.53
1.356GlyHis: 1.356 ± 0.037
2.712GlyIle: 2.712 ± 1.973
3.39GlyLys: 3.39 ± 0.568
6.102GlyLeu: 6.102 ± 1.591
0.0GlyMet: 0.0 ± 0.0
2.034GlyAsn: 2.034 ± 0.53
5.424GlyPro: 5.424 ± 1.098
2.712GlyGln: 2.712 ± 1.024
2.712GlyArg: 2.712 ± 0.075
5.424GlySer: 5.424 ± 1.098
0.0GlyThr: 0.0 ± 0.0
0.678GlyVal: 0.678 ± 0.456
0.0GlyTrp: 0.0 ± 0.0
0.678GlyTyr: 0.678 ± 0.456
0.0GlyXaa: 0.0 ± 0.0
His
2.034HisAla: 2.034 ± 1.479
0.0HisCys: 0.0 ± 0.0
0.678HisAsp: 0.678 ± 0.493
2.034HisGlu: 2.034 ± 0.419
0.678HisPhe: 0.678 ± 0.456
1.356HisGly: 1.356 ± 0.037
2.034HisHis: 2.034 ± 0.419
2.712HisIle: 2.712 ± 1.024
0.678HisLys: 0.678 ± 0.456
1.356HisLeu: 1.356 ± 0.037
0.678HisMet: 0.678 ± 0.456
2.034HisAsn: 2.034 ± 0.419
4.068HisPro: 4.068 ± 0.837
0.678HisGln: 0.678 ± 0.456
4.746HisArg: 4.746 ± 0.605
2.712HisSer: 2.712 ± 0.874
1.356HisThr: 1.356 ± 0.037
2.034HisVal: 2.034 ± 1.367
1.356HisTrp: 1.356 ± 0.037
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.068IleAla: 4.068 ± 0.112
0.678IleCys: 0.678 ± 0.456
2.712IleAsp: 2.712 ± 0.874
2.712IleGlu: 2.712 ± 0.075
2.034IlePhe: 2.034 ± 0.53
0.0IleGly: 0.0 ± 0.0
2.034IleHis: 2.034 ± 1.479
2.034IleIle: 2.034 ± 0.53
2.034IleLys: 2.034 ± 0.419
5.424IleLeu: 5.424 ± 0.149
1.356IleMet: 1.356 ± 0.037
8.136IleAsn: 8.136 ± 0.725
4.068IlePro: 4.068 ± 0.112
3.39IleGln: 3.39 ± 1.517
4.068IleArg: 4.068 ± 1.061
5.424IleSer: 5.424 ± 0.8
4.746IleThr: 4.746 ± 1.293
4.068IleVal: 4.068 ± 0.112
0.0IleTrp: 0.0 ± 0.0
4.746IleTyr: 4.746 ± 1.293
0.0IleXaa: 0.0 ± 0.0
Lys
4.746LysAla: 4.746 ± 0.605
0.0LysCys: 0.0 ± 0.0
3.39LysAsp: 3.39 ± 0.381
2.712LysGlu: 2.712 ± 1.823
0.0LysPhe: 0.0 ± 0.0
1.356LysGly: 1.356 ± 0.037
1.356LysHis: 1.356 ± 0.912
2.712LysIle: 2.712 ± 0.075
1.356LysLys: 1.356 ± 0.037
2.034LysLeu: 2.034 ± 0.419
2.712LysMet: 2.712 ± 0.874
0.678LysAsn: 0.678 ± 0.456
2.034LysPro: 2.034 ± 0.53
2.712LysGln: 2.712 ± 1.823
2.712LysArg: 2.712 ± 0.075
2.712LysSer: 2.712 ± 1.823
3.39LysThr: 3.39 ± 0.381
2.034LysVal: 2.034 ± 1.479
0.0LysTrp: 0.0 ± 0.0
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
5.424LeuAla: 5.424 ± 2.047
2.034LeuCys: 2.034 ± 1.367
10.847LeuAsp: 10.847 ± 3.145
4.068LeuGlu: 4.068 ± 1.786
6.102LeuPhe: 6.102 ± 0.642
6.102LeuGly: 6.102 ± 1.591
1.356LeuHis: 1.356 ± 0.912
4.068LeuIle: 4.068 ± 1.061
4.068LeuLys: 4.068 ± 0.837
10.847LeuLeu: 10.847 ± 3.497
0.0LeuMet: 0.0 ± 0.0
7.458LeuAsn: 7.458 ± 0.269
7.458LeuPro: 7.458 ± 4.065
4.746LeuGln: 4.746 ± 0.344
9.492LeuArg: 9.492 ± 2.586
6.102LeuSer: 6.102 ± 1.256
6.78LeuThr: 6.78 ± 0.762
2.034LeuVal: 2.034 ± 0.53
3.39LeuTrp: 3.39 ± 1.33
2.034LeuTyr: 2.034 ± 0.419
0.0LeuXaa: 0.0 ± 0.0
Met
1.356MetAla: 1.356 ± 0.986
0.0MetCys: 0.0 ± 0.0
0.678MetAsp: 0.678 ± 0.456
0.678MetGlu: 0.678 ± 0.456
1.356MetPhe: 1.356 ± 0.986
0.0MetGly: 0.0 ± 0.0
0.678MetHis: 0.678 ± 0.456
2.712MetIle: 2.712 ± 0.075
1.356MetLys: 1.356 ± 0.912
4.068MetLeu: 4.068 ± 1.786
0.0MetMet: 0.0 ± 0.0
0.678MetAsn: 0.678 ± 0.456
0.678MetPro: 0.678 ± 0.493
1.356MetGln: 1.356 ± 0.037
0.678MetArg: 0.678 ± 0.456
1.356MetSer: 1.356 ± 0.986
0.678MetThr: 0.678 ± 0.456
2.034MetVal: 2.034 ± 1.479
0.678MetTrp: 0.678 ± 0.493
0.678MetTyr: 0.678 ± 0.456
0.0MetXaa: 0.0 ± 0.0
Asn
5.424AsnAla: 5.424 ± 1.098
2.712AsnCys: 2.712 ± 0.075
3.39AsnAsp: 3.39 ± 0.381
2.034AsnGlu: 2.034 ± 0.53
1.356AsnPhe: 1.356 ± 0.986
4.068AsnGly: 4.068 ± 2.01
0.678AsnHis: 0.678 ± 0.456
2.034AsnIle: 2.034 ± 0.53
4.068AsnLys: 4.068 ± 1.786
4.068AsnLeu: 4.068 ± 0.837
0.678AsnMet: 0.678 ± 0.456
2.034AsnAsn: 2.034 ± 1.479
5.424AsnPro: 5.424 ± 0.149
2.712AsnGln: 2.712 ± 0.075
4.068AsnArg: 4.068 ± 0.837
6.102AsnSer: 6.102 ± 0.642
4.746AsnThr: 4.746 ± 0.605
2.712AsnVal: 2.712 ± 0.075
1.356AsnTrp: 1.356 ± 0.037
1.356AsnTyr: 1.356 ± 0.912
0.0AsnXaa: 0.0 ± 0.0
Pro
7.458ProAla: 7.458 ± 0.68
3.39ProCys: 3.39 ± 0.568
3.39ProAsp: 3.39 ± 1.33
1.356ProGlu: 1.356 ± 0.986
2.034ProPhe: 2.034 ± 0.419
4.746ProGly: 4.746 ± 2.503
2.712ProHis: 2.712 ± 0.075
2.712ProIle: 2.712 ± 0.874
2.712ProLys: 2.712 ± 1.024
10.847ProLeu: 10.847 ± 2.196
0.678ProMet: 0.678 ± 0.456
2.034ProAsn: 2.034 ± 0.53
2.712ProPro: 2.712 ± 1.024
4.746ProGln: 4.746 ± 0.605
6.102ProArg: 6.102 ± 0.642
6.102ProSer: 6.102 ± 1.256
0.678ProThr: 0.678 ± 0.456
2.712ProVal: 2.712 ± 0.874
0.678ProTrp: 0.678 ± 0.456
2.034ProTyr: 2.034 ± 0.419
0.0ProXaa: 0.0 ± 0.0
Gln
2.712GlnAla: 2.712 ± 0.075
0.678GlnCys: 0.678 ± 0.456
3.39GlnAsp: 3.39 ± 0.568
0.678GlnGlu: 0.678 ± 0.456
0.678GlnPhe: 0.678 ± 0.493
3.39GlnGly: 3.39 ± 1.517
1.356GlnHis: 1.356 ± 0.912
3.39GlnIle: 3.39 ± 1.517
0.0GlnLys: 0.0 ± 0.0
6.102GlnLeu: 6.102 ± 0.307
2.034GlnMet: 2.034 ± 0.53
2.034GlnAsn: 2.034 ± 1.479
2.712GlnPro: 2.712 ± 1.024
2.034GlnGln: 2.034 ± 0.419
3.39GlnArg: 3.39 ± 0.381
4.068GlnSer: 4.068 ± 1.061
1.356GlnThr: 1.356 ± 0.037
2.712GlnVal: 2.712 ± 0.874
0.678GlnTrp: 0.678 ± 0.456
1.356GlnTyr: 1.356 ± 0.037
0.0GlnXaa: 0.0 ± 0.0
Arg
4.746ArgAla: 4.746 ± 2.242
1.356ArgCys: 1.356 ± 0.912
2.034ArgAsp: 2.034 ± 0.419
2.034ArgGlu: 2.034 ± 0.419
2.712ArgPhe: 2.712 ± 0.874
2.712ArgGly: 2.712 ± 1.024
3.39ArgHis: 3.39 ± 0.381
5.424ArgIle: 5.424 ± 0.8
4.068ArgLys: 4.068 ± 0.112
4.746ArgLeu: 4.746 ± 0.344
0.678ArgMet: 0.678 ± 0.493
4.068ArgAsn: 4.068 ± 0.112
6.78ArgPro: 6.78 ± 4.931
2.034ArgGln: 2.034 ± 0.419
3.39ArgArg: 3.39 ± 0.381
3.39ArgSer: 3.39 ± 1.33
2.034ArgThr: 2.034 ± 0.419
2.712ArgVal: 2.712 ± 0.874
0.0ArgTrp: 0.0 ± 0.0
4.746ArgTyr: 4.746 ± 0.605
0.0ArgXaa: 0.0 ± 0.0
Ser
5.424SerAla: 5.424 ± 0.8
0.678SerCys: 0.678 ± 0.493
4.746SerAsp: 4.746 ± 0.344
0.678SerGlu: 0.678 ± 0.493
6.78SerPhe: 6.78 ± 1.136
4.746SerGly: 4.746 ± 2.242
2.712SerHis: 2.712 ± 0.075
6.102SerIle: 6.102 ± 1.256
1.356SerLys: 1.356 ± 0.037
5.424SerLeu: 5.424 ± 0.8
4.068SerMet: 4.068 ± 1.061
3.39SerAsn: 3.39 ± 0.568
4.746SerPro: 4.746 ± 0.605
3.39SerGln: 3.39 ± 0.568
4.068SerArg: 4.068 ± 0.837
4.068SerSer: 4.068 ± 0.837
4.746SerThr: 4.746 ± 0.605
2.034SerVal: 2.034 ± 1.367
0.0SerTrp: 0.0 ± 0.0
2.712SerTyr: 2.712 ± 0.874
0.0SerXaa: 0.0 ± 0.0
Thr
4.068ThrAla: 4.068 ± 0.112
2.034ThrCys: 2.034 ± 0.53
2.712ThrAsp: 2.712 ± 1.024
2.034ThrGlu: 2.034 ± 0.53
3.39ThrPhe: 3.39 ± 1.33
1.356ThrGly: 1.356 ± 0.037
2.712ThrHis: 2.712 ± 0.874
1.356ThrIle: 1.356 ± 0.037
3.39ThrLys: 3.39 ± 0.381
9.492ThrLeu: 9.492 ± 0.261
2.034ThrMet: 2.034 ± 0.419
2.712ThrAsn: 2.712 ± 1.024
2.034ThrPro: 2.034 ± 0.419
2.034ThrGln: 2.034 ± 0.53
4.068ThrArg: 4.068 ± 0.112
4.068ThrSer: 4.068 ± 0.837
2.034ThrThr: 2.034 ± 0.53
5.424ThrVal: 5.424 ± 0.149
0.0ThrTrp: 0.0 ± 0.0
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
2.034ValAla: 2.034 ± 0.53
0.678ValCys: 0.678 ± 0.456
2.712ValAsp: 2.712 ± 0.075
2.034ValGlu: 2.034 ± 0.419
2.712ValPhe: 2.712 ± 0.075
0.678ValGly: 0.678 ± 0.456
1.356ValHis: 1.356 ± 0.986
4.746ValIle: 4.746 ± 0.344
1.356ValLys: 1.356 ± 0.912
5.424ValLeu: 5.424 ± 0.8
0.678ValMet: 0.678 ± 0.271
6.102ValAsn: 6.102 ± 1.591
4.068ValPro: 4.068 ± 0.837
2.034ValGln: 2.034 ± 0.419
2.034ValArg: 2.034 ± 1.285
4.746ValSer: 4.746 ± 0.605
3.39ValThr: 3.39 ± 1.33
5.424ValVal: 5.424 ± 1.098
0.678ValTrp: 0.678 ± 0.456
2.034ValTyr: 2.034 ± 0.419
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.678TrpCys: 0.678 ± 0.456
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.678TrpIle: 0.678 ± 0.456
0.0TrpLys: 0.0 ± 0.0
2.034TrpLeu: 2.034 ± 0.419
0.678TrpMet: 0.678 ± 0.456
1.356TrpAsn: 1.356 ± 0.037
1.356TrpPro: 1.356 ± 0.037
0.678TrpGln: 0.678 ± 0.456
0.678TrpArg: 0.678 ± 0.493
0.678TrpSer: 0.678 ± 0.456
0.0TrpThr: 0.0 ± 0.0
1.356TrpVal: 1.356 ± 0.037
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.034TyrAla: 2.034 ± 0.419
0.678TyrCys: 0.678 ± 0.456
4.068TyrAsp: 4.068 ± 0.837
0.678TyrGlu: 0.678 ± 0.456
0.678TyrPhe: 0.678 ± 0.456
0.678TyrGly: 0.678 ± 0.493
1.356TyrHis: 1.356 ± 0.037
4.068TyrIle: 4.068 ± 2.735
2.034TyrLys: 2.034 ± 1.367
4.746TyrLeu: 4.746 ± 0.344
1.356TyrMet: 1.356 ± 0.912
2.034TyrAsn: 2.034 ± 0.53
2.034TyrPro: 2.034 ± 0.419
1.356TyrGln: 1.356 ± 0.986
0.0TyrArg: 0.0 ± 0.0
1.356TyrSer: 1.356 ± 0.037
3.39TyrThr: 3.39 ± 0.568
2.034TyrVal: 2.034 ± 0.53
0.0TyrTrp: 0.0 ± 0.0
2.034TyrTyr: 2.034 ± 1.479
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1476 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski