Loa loa (Eye worm) (Filaria loa)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Loa

Average proteome isoelectric point is 6.83

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 12177 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A1I7W4J4|A0A1I7W4J4_LOALO Oxidoreductase OS=Loa loa OX=7209 GN=LOAG_10783 PE=3 SV=1
MM1 pKa = 7.4TIVVMYY7 pKa = 9.88HH8 pKa = 4.59YY9 pKa = 11.04VRR11 pKa = 11.84LINKK15 pKa = 9.49LYY17 pKa = 10.28ISLINLFADD26 pKa = 5.02RR27 pKa = 11.84IDD29 pKa = 5.36DD30 pKa = 4.05NFCGPLLLQSPMNEE44 pKa = 3.83NVCQRR49 pKa = 11.84TTNYY53 pKa = 10.75NDD55 pKa = 3.23IANVNDD61 pKa = 5.2GDD63 pKa = 4.48DD64 pKa = 4.21CDD66 pKa = 6.3DD67 pKa = 5.9RR68 pKa = 11.84DD69 pKa = 5.65DD70 pKa = 6.51DD71 pKa = 6.25DD72 pKa = 7.63DD73 pKa = 6.82DD74 pKa = 7.08DD75 pKa = 4.46EE76 pKa = 4.56TLSMTFF82 pKa = 3.52

Molecular weight: 9.52 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A1I7VKI2|A0A1I7VKI2_LOALO Uncharacterized protein OS=Loa loa OX=7209 PE=4 SV=1
MM1 pKa = 8.17PYY3 pKa = 9.89RR4 pKa = 11.84RR5 pKa = 11.84SQSRR9 pKa = 11.84TRR11 pKa = 11.84RR12 pKa = 11.84GRR14 pKa = 11.84SRR16 pKa = 11.84SRR18 pKa = 11.84TSRR21 pKa = 11.84RR22 pKa = 11.84NVASLSLLSMRR33 pKa = 11.84RR34 pKa = 11.84RR35 pKa = 11.84RR36 pKa = 11.84GLRR39 pKa = 11.84LRR41 pKa = 11.84SRR43 pKa = 11.84SQVGFDD49 pKa = 3.95LGRR52 pKa = 11.84LLSSRR57 pKa = 11.84RR58 pKa = 11.84RR59 pKa = 11.84RR60 pKa = 11.84PTYY63 pKa = 9.07RR64 pKa = 11.84SRR66 pKa = 11.84SRR68 pKa = 11.84RR69 pKa = 11.84SSYY72 pKa = 9.78RR73 pKa = 11.84SRR75 pKa = 11.84SIRR78 pKa = 11.84SLRR81 pKa = 11.84RR82 pKa = 11.84HH83 pKa = 5.78RR84 pKa = 11.84PSNIRR89 pKa = 11.84RR90 pKa = 11.84RR91 pKa = 11.84RR92 pKa = 11.84HH93 pKa = 4.56SSSRR97 pKa = 11.84SRR99 pKa = 11.84RR100 pKa = 11.84RR101 pKa = 11.84QFRR104 pKa = 11.84SRR106 pKa = 11.84RR107 pKa = 11.84RR108 pKa = 11.84SRR110 pKa = 11.84SRR112 pKa = 11.84RR113 pKa = 11.84LSRR116 pKa = 11.84SRR118 pKa = 11.84RR119 pKa = 11.84LSRR122 pKa = 11.84SRR124 pKa = 11.84RR125 pKa = 11.84RR126 pKa = 11.84SRR128 pKa = 11.84SRR130 pKa = 11.84SGSRR134 pKa = 11.84TYY136 pKa = 10.1PYY138 pKa = 10.23RR139 pKa = 11.84IRR141 pKa = 11.84RR142 pKa = 11.84RR143 pKa = 11.84LRR145 pKa = 3.31

Molecular weight: 18.17 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

12152

25

12177

5044833

41

6813

414.3

46.93

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.106 ± 0.018

2.105 ± 0.019

5.522 ± 0.026

6.856 ± 0.029

3.942 ± 0.017

5.151 ± 0.023

2.411 ± 0.011

6.544 ± 0.027

6.274 ± 0.024

9.136 ± 0.031

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.485 ± 0.009

5.014 ± 0.016

4.379 ± 0.024

4.225 ± 0.023

5.812 ± 0.023

8.057 ± 0.034

5.693 ± 0.021

6.009 ± 0.03

1.118 ± 0.008

3.157 ± 0.017
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski