Amino acid dipepetide frequency for Alcanivorax dieselolei (strain DSM 16502 / CGMCC 1.3690 / B-5)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.12AlaAla: 12.12 ± 0.122	1.069AlaCys: 1.069 ± 0.026	6.216AlaAsp: 6.216 ± 0.077	6.557AlaGlu: 6.557 ± 0.078	3.685AlaPhe: 3.685 ± 0.055	9.681AlaGly: 9.681 ± 0.121	1.999AlaHis: 1.999 ± 0.039	4.517AlaIle: 4.517 ± 0.061	2.627AlaLys: 2.627 ± 0.053	13.92AlaLeu: 13.92 ± 0.127	2.974AlaMet: 2.974 ± 0.049	2.677AlaAsn: 2.677 ± 0.048	4.888AlaPro: 4.888 ± 0.07	3.65AlaGln: 3.65 ± 0.053	8.215AlaArg: 8.215 ± 0.107	5.507AlaSer: 5.507 ± 0.075	5.046AlaThr: 5.046 ± 0.073	7.743AlaVal: 7.743 ± 0.08	1.575AlaTrp: 1.575 ± 0.04	2.319AlaTyr: 2.319 ± 0.043	0.0AlaXaa: 0.0 ± 0.0
Cys	0.938CysAla: 0.938 ± 0.025	0.139CysCys: 0.139 ± 0.01	0.59CysAsp: 0.59 ± 0.021	0.524CysGlu: 0.524 ± 0.019	0.339CysPhe: 0.339 ± 0.016	0.942CysGly: 0.942 ± 0.028	0.313CysHis: 0.313 ± 0.015	0.322CysIle: 0.322 ± 0.015	0.197CysLys: 0.197 ± 0.012	0.986CysLeu: 0.986 ± 0.029	0.175CysMet: 0.175 ± 0.011	0.203CysAsn: 0.203 ± 0.012	0.557CysPro: 0.557 ± 0.023	0.386CysGln: 0.386 ± 0.018	0.721CysArg: 0.721 ± 0.023	0.48CysSer: 0.48 ± 0.022	0.401CysThr: 0.401 ± 0.017	0.603CysVal: 0.603 ± 0.021	0.124CysTrp: 0.124 ± 0.01	0.241CysTyr: 0.241 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	6.097AspAla: 6.097 ± 0.067	0.48AspCys: 0.48 ± 0.017	3.83AspAsp: 3.83 ± 0.064	3.53AspGlu: 3.53 ± 0.052	2.041AspPhe: 2.041 ± 0.038	5.487AspGly: 5.487 ± 0.1	1.49AspHis: 1.49 ± 0.031	2.717AspIle: 2.717 ± 0.048	1.692AspLys: 1.692 ± 0.045	6.234AspLeu: 6.234 ± 0.075	1.361AspMet: 1.361 ± 0.036	1.872AspAsn: 1.872 ± 0.039	3.254AspPro: 3.254 ± 0.053	2.707AspGln: 2.707 ± 0.046	4.014AspArg: 4.014 ± 0.054	2.859AspSer: 2.859 ± 0.047	3.152AspThr: 3.152 ± 0.056	3.953AspVal: 3.953 ± 0.058	1.123AspTrp: 1.123 ± 0.031	1.972AspTyr: 1.972 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	6.712GluAla: 6.712 ± 0.081	0.452GluCys: 0.452 ± 0.017	3.232GluAsp: 3.232 ± 0.048	3.891GluGlu: 3.891 ± 0.066	1.685GluPhe: 1.685 ± 0.034	4.532GluGly: 4.532 ± 0.065	1.626GluHis: 1.626 ± 0.038	2.655GluIle: 2.655 ± 0.047	2.224GluLys: 2.224 ± 0.049	6.074GluLeu: 6.074 ± 0.074	1.422GluMet: 1.422 ± 0.031	1.754GluAsn: 1.754 ± 0.036	2.756GluPro: 2.756 ± 0.061	3.854GluGln: 3.854 ± 0.06	5.173GluArg: 5.173 ± 0.066	2.903GluSer: 2.903 ± 0.046	3.082GluThr: 3.082 ± 0.047	4.263GluVal: 4.263 ± 0.063	0.785GluTrp: 0.785 ± 0.023	1.456GluTyr: 1.456 ± 0.036	0.0GluXaa: 0.0 ± 0.0
Phe	3.407PheAla: 3.407 ± 0.052	0.39PheCys: 0.39 ± 0.018	2.435PheAsp: 2.435 ± 0.043	2.008PheGlu: 2.008 ± 0.046	1.418PhePhe: 1.418 ± 0.036	3.141PheGly: 3.141 ± 0.049	0.883PheHis: 0.883 ± 0.024	1.556PheIle: 1.556 ± 0.036	0.949PheLys: 0.949 ± 0.026	3.492PheLeu: 3.492 ± 0.058	0.812PheMet: 0.812 ± 0.026	1.171PheAsn: 1.171 ± 0.032	1.626PhePro: 1.626 ± 0.032	1.375PheGln: 1.375 ± 0.031	2.138PheArg: 2.138 ± 0.04	2.326PheSer: 2.326 ± 0.038	1.954PheThr: 1.954 ± 0.041	2.333PheVal: 2.333 ± 0.046	0.545PheTrp: 0.545 ± 0.022	1.001PheTyr: 1.001 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	8.317GlyAla: 8.317 ± 0.1	0.919GlyCys: 0.919 ± 0.029	5.197GlyAsp: 5.197 ± 0.104	5.583GlyGlu: 5.583 ± 0.067	3.279GlyPhe: 3.279 ± 0.052	7.393GlyGly: 7.393 ± 0.13	2.008GlyHis: 2.008 ± 0.039	4.022GlyIle: 4.022 ± 0.062	2.865GlyLys: 2.865 ± 0.05	9.147GlyLeu: 9.147 ± 0.091	2.296GlyMet: 2.296 ± 0.042	2.454GlyAsn: 2.454 ± 0.069	3.0GlyPro: 3.0 ± 0.049	3.372GlyGln: 3.372 ± 0.062	5.628GlyArg: 5.628 ± 0.069	4.385GlySer: 4.385 ± 0.076	4.247GlyThr: 4.247 ± 0.082	6.382GlyVal: 6.382 ± 0.079	1.459GlyTrp: 1.459 ± 0.032	2.61GlyTyr: 2.61 ± 0.045	0.0GlyXaa: 0.0 ± 0.0
His	2.018HisAla: 2.018 ± 0.035	0.327HisCys: 0.327 ± 0.015	1.265HisAsp: 1.265 ± 0.028	1.086HisGlu: 1.086 ± 0.032	1.005HisPhe: 1.005 ± 0.025	2.175HisGly: 2.175 ± 0.041	0.794HisHis: 0.794 ± 0.025	0.921HisIle: 0.921 ± 0.027	0.535HisLys: 0.535 ± 0.022	2.494HisLeu: 2.494 ± 0.049	0.484HisMet: 0.484 ± 0.02	0.64HisAsn: 0.64 ± 0.02	1.463HisPro: 1.463 ± 0.038	1.072HisGln: 1.072 ± 0.028	1.857HisArg: 1.857 ± 0.037	1.147HisSer: 1.147 ± 0.032	1.065HisThr: 1.065 ± 0.027	1.294HisVal: 1.294 ± 0.031	0.521HisTrp: 0.521 ± 0.019	0.837HisTyr: 0.837 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	4.765IleAla: 4.765 ± 0.066	0.405IleCys: 0.405 ± 0.017	2.903IleAsp: 2.903 ± 0.051	2.851IleGlu: 2.851 ± 0.047	1.274IlePhe: 1.274 ± 0.034	4.02IleGly: 4.02 ± 0.064	1.004IleHis: 1.004 ± 0.029	1.907IleIle: 1.907 ± 0.042	1.402IleLys: 1.402 ± 0.033	3.994IleLeu: 3.994 ± 0.063	0.908IleMet: 0.908 ± 0.024	1.632IleAsn: 1.632 ± 0.044	2.227IlePro: 2.227 ± 0.043	1.573IleGln: 1.573 ± 0.039	3.077IleArg: 3.077 ± 0.053	2.611IleSer: 2.611 ± 0.046	2.685IleThr: 2.685 ± 0.048	2.89IleVal: 2.89 ± 0.047	0.532IleTrp: 0.532 ± 0.018	1.089IleTyr: 1.089 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	3.415LysAla: 3.415 ± 0.068	0.154LysCys: 0.154 ± 0.01	1.586LysAsp: 1.586 ± 0.039	1.786LysGlu: 1.786 ± 0.038	0.622LysPhe: 0.622 ± 0.022	2.293LysGly: 2.293 ± 0.048	0.58LysHis: 0.58 ± 0.019	1.167LysIle: 1.167 ± 0.035	1.252LysLys: 1.252 ± 0.042	2.818LysLeu: 2.818 ± 0.053	0.661LysMet: 0.661 ± 0.025	0.816LysAsn: 0.816 ± 0.026	1.681LysPro: 1.681 ± 0.046	1.239LysGln: 1.239 ± 0.03	2.051LysArg: 2.051 ± 0.042	1.428LysSer: 1.428 ± 0.032	1.6LysThr: 1.6 ± 0.035	2.478LysVal: 2.478 ± 0.052	0.319LysTrp: 0.319 ± 0.014	0.642LysTyr: 0.642 ± 0.024	0.0LysXaa: 0.0 ± 0.0
Leu	13.233LeuAla: 13.233 ± 0.127	1.11LeuCys: 1.11 ± 0.032	6.812LeuAsp: 6.812 ± 0.088	6.728LeuGlu: 6.728 ± 0.085	4.003LeuPhe: 4.003 ± 0.071	8.946LeuGly: 8.946 ± 0.096	2.333LeuHis: 2.333 ± 0.038	5.083LeuIle: 5.083 ± 0.067	3.389LeuLys: 3.389 ± 0.053	12.028LeuLeu: 12.028 ± 0.135	2.72LeuMet: 2.72 ± 0.055	3.239LeuAsn: 3.239 ± 0.048	6.213LeuPro: 6.213 ± 0.082	3.512LeuGln: 3.512 ± 0.052	7.804LeuArg: 7.804 ± 0.082	7.02LeuSer: 7.02 ± 0.083	5.898LeuThr: 5.898 ± 0.07	8.029LeuVal: 8.029 ± 0.09	1.52LeuTrp: 1.52 ± 0.035	2.664LeuTyr: 2.664 ± 0.046	0.0LeuXaa: 0.0 ± 0.0
Met	2.964MetAla: 2.964 ± 0.044	0.141MetCys: 0.141 ± 0.011	1.318MetAsp: 1.318 ± 0.033	1.381MetGlu: 1.381 ± 0.033	0.649MetPhe: 0.649 ± 0.022	1.828MetGly: 1.828 ± 0.035	0.434MetHis: 0.434 ± 0.017	1.193MetIle: 1.193 ± 0.035	0.904MetLys: 0.904 ± 0.022	2.547MetLeu: 2.547 ± 0.049	0.7MetMet: 0.7 ± 0.025	0.819MetAsn: 0.819 ± 0.021	1.303MetPro: 1.303 ± 0.031	0.83MetGln: 0.83 ± 0.024	1.521MetArg: 1.521 ± 0.033	1.639MetSer: 1.639 ± 0.03	1.621MetThr: 1.621 ± 0.035	1.837MetVal: 1.837 ± 0.041	0.186MetTrp: 0.186 ± 0.012	0.391MetTyr: 0.391 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	2.972AsnAla: 2.972 ± 0.055	0.226AsnCys: 0.226 ± 0.012	1.775AsnAsp: 1.775 ± 0.041	1.512AsnGlu: 1.512 ± 0.027	0.871AsnPhe: 0.871 ± 0.026	2.81AsnGly: 2.81 ± 0.071	0.611AsnHis: 0.611 ± 0.021	1.283AsnIle: 1.283 ± 0.033	0.788AsnLys: 0.788 ± 0.025	2.976AsnLeu: 2.976 ± 0.049	0.638AsnMet: 0.638 ± 0.019	0.919AsnAsn: 0.919 ± 0.025	1.837AsnPro: 1.837 ± 0.039	1.233AsnGln: 1.233 ± 0.026	2.071AsnArg: 2.071 ± 0.04	1.332AsnSer: 1.332 ± 0.033	1.561AsnThr: 1.561 ± 0.035	1.945AsnVal: 1.945 ± 0.047	0.44AsnTrp: 0.44 ± 0.016	0.776AsnTyr: 0.776 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	5.558ProAla: 5.558 ± 0.077	0.35ProCys: 0.35 ± 0.015	3.617ProAsp: 3.617 ± 0.061	4.111ProGlu: 4.111 ± 0.054	1.784ProPhe: 1.784 ± 0.033	4.517ProGly: 4.517 ± 0.066	1.013ProHis: 1.013 ± 0.025	1.806ProIle: 1.806 ± 0.038	1.285ProLys: 1.285 ± 0.04	5.614ProLeu: 5.614 ± 0.069	1.292ProMet: 1.292 ± 0.03	1.215ProAsn: 1.215 ± 0.031	2.458ProPro: 2.458 ± 0.05	1.724ProGln: 1.724 ± 0.037	3.04ProArg: 3.04 ± 0.045	2.582ProSer: 2.582 ± 0.038	2.06ProThr: 2.06 ± 0.04	4.431ProVal: 4.431 ± 0.058	0.865ProTrp: 0.865 ± 0.027	1.222ProTyr: 1.222 ± 0.027	0.0ProXaa: 0.0 ± 0.0
Gln	5.035GlnAla: 5.035 ± 0.072	0.368GlnCys: 0.368 ± 0.019	1.997GlnAsp: 1.997 ± 0.038	2.09GlnGlu: 2.09 ± 0.044	1.162GlnPhe: 1.162 ± 0.027	3.393GlnGly: 3.393 ± 0.053	0.927GlnHis: 0.927 ± 0.025	1.549GlnIle: 1.549 ± 0.031	1.088GlnLys: 1.088 ± 0.029	4.102GlnLeu: 4.102 ± 0.06	0.856GlnMet: 0.856 ± 0.024	0.995GlnAsn: 0.995 ± 0.028	2.128GlnPro: 2.128 ± 0.043	2.194GlnGln: 2.194 ± 0.051	3.659GlnArg: 3.659 ± 0.064	2.091GlnSer: 2.091 ± 0.039	1.705GlnThr: 1.705 ± 0.037	3.268GlnVal: 3.268 ± 0.053	0.805GlnTrp: 0.805 ± 0.023	0.958GlnTyr: 0.958 ± 0.026	0.0GlnXaa: 0.0 ± 0.0
Arg	6.974ArgAla: 6.974 ± 0.084	0.638ArgCys: 0.638 ± 0.025	4.526ArgAsp: 4.526 ± 0.066	4.811ArgGlu: 4.811 ± 0.06	3.153ArgPhe: 3.153 ± 0.049	4.685ArgGly: 4.685 ± 0.056	2.207ArgHis: 2.207 ± 0.043	3.522ArgIle: 3.522 ± 0.047	2.024ArgLys: 2.024 ± 0.038	8.892ArgLeu: 8.892 ± 0.109	1.655ArgMet: 1.655 ± 0.034	2.006ArgAsn: 2.006 ± 0.038	3.347ArgPro: 3.347 ± 0.056	3.608ArgGln: 3.608 ± 0.059	6.235ArgArg: 6.235 ± 0.096	3.192ArgSer: 3.192 ± 0.053	3.107ArgThr: 3.107 ± 0.049	5.108ArgVal: 5.108 ± 0.064	1.306ArgTrp: 1.306 ± 0.029	2.321ArgTyr: 2.321 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	5.572SerAla: 5.572 ± 0.064	0.478SerCys: 0.478 ± 0.019	3.101SerAsp: 3.101 ± 0.048	3.055SerGlu: 3.055 ± 0.045	1.846SerPhe: 1.846 ± 0.038	5.539SerGly: 5.539 ± 0.08	1.18SerHis: 1.18 ± 0.031	2.16SerIle: 2.16 ± 0.046	1.4SerLys: 1.4 ± 0.032	6.135SerLeu: 6.135 ± 0.063	1.381SerMet: 1.381 ± 0.033	1.506SerAsn: 1.506 ± 0.04	2.728SerPro: 2.728 ± 0.045	1.93SerGln: 1.93 ± 0.034	3.893SerArg: 3.893 ± 0.054	3.032SerSer: 3.032 ± 0.06	2.622SerThr: 2.622 ± 0.052	3.971SerVal: 3.971 ± 0.055	0.79SerTrp: 0.79 ± 0.022	1.417SerTyr: 1.417 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	5.076ThrAla: 5.076 ± 0.08	0.396ThrCys: 0.396 ± 0.019	2.778ThrAsp: 2.778 ± 0.057	2.695ThrGlu: 2.695 ± 0.05	1.826ThrPhe: 1.826 ± 0.041	4.758ThrGly: 4.758 ± 0.073	1.015ThrHis: 1.015 ± 0.027	2.052ThrIle: 2.052 ± 0.038	0.969ThrLys: 0.969 ± 0.029	7.221ThrLeu: 7.221 ± 0.086	1.029ThrMet: 1.029 ± 0.03	1.202ThrAsn: 1.202 ± 0.038	3.241ThrPro: 3.241 ± 0.048	1.577ThrGln: 1.577 ± 0.038	3.358ThrArg: 3.358 ± 0.05	2.551ThrSer: 2.551 ± 0.044	2.579ThrThr: 2.579 ± 0.052	4.531ThrVal: 4.531 ± 0.069	0.739ThrTrp: 0.739 ± 0.023	1.125ThrTyr: 1.125 ± 0.033	0.0ThrXaa: 0.0 ± 0.0
Val	8.258ValAla: 8.258 ± 0.09	0.67ValCys: 0.67 ± 0.023	4.478ValAsp: 4.478 ± 0.064	4.454ValGlu: 4.454 ± 0.061	2.661ValPhe: 2.661 ± 0.046	5.16ValGly: 5.16 ± 0.076	1.519ValHis: 1.519 ± 0.032	3.733ValIle: 3.733 ± 0.054	2.0ValLys: 2.0 ± 0.045	8.339ValLeu: 8.339 ± 0.084	1.94ValMet: 1.94 ± 0.039	2.291ValAsn: 2.291 ± 0.046	3.721ValPro: 3.721 ± 0.06	2.197ValGln: 2.197 ± 0.046	5.01ValArg: 5.01 ± 0.072	4.427ValSer: 4.427 ± 0.056	4.396ValThr: 4.396 ± 0.062	6.012ValVal: 6.012 ± 0.076	0.898ValTrp: 0.898 ± 0.026	1.631ValTyr: 1.631 ± 0.032	0.0ValXaa: 0.0 ± 0.0
Trp	1.195TrpAla: 1.195 ± 0.028	0.168TrpCys: 0.168 ± 0.01	0.686TrpAsp: 0.686 ± 0.025	0.709TrpGlu: 0.709 ± 0.025	0.594TrpPhe: 0.594 ± 0.022	0.998TrpGly: 0.998 ± 0.028	0.409TrpHis: 0.409 ± 0.017	0.659TrpIle: 0.659 ± 0.023	0.406TrpLys: 0.406 ± 0.017	2.275TrpLeu: 2.275 ± 0.048	0.403TrpMet: 0.403 ± 0.017	0.441TrpAsn: 0.441 ± 0.019	0.767TrpPro: 0.767 ± 0.025	0.863TrpGln: 0.863 ± 0.031	1.497TrpArg: 1.497 ± 0.036	0.839TrpSer: 0.839 ± 0.025	0.633TrpThr: 0.633 ± 0.023	1.051TrpVal: 1.051 ± 0.028	0.271TrpTrp: 0.271 ± 0.016	0.353TrpTyr: 0.353 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.362TyrAla: 2.362 ± 0.045	0.3TyrCys: 0.3 ± 0.015	1.523TyrAsp: 1.523 ± 0.043	1.169TyrGlu: 1.169 ± 0.028	1.062TyrPhe: 1.062 ± 0.022	2.267TyrGly: 2.267 ± 0.045	0.656TyrHis: 0.656 ± 0.022	0.924TyrIle: 0.924 ± 0.027	0.591TyrLys: 0.591 ± 0.023	2.998TyrLeu: 2.998 ± 0.047	0.497TyrMet: 0.497 ± 0.021	0.723TyrAsn: 0.723 ± 0.022	1.349TyrPro: 1.349 ± 0.031	1.471TyrGln: 1.471 ± 0.035	2.356TyrArg: 2.356 ± 0.041	1.386TyrSer: 1.386 ± 0.032	1.305TyrThr: 1.305 ± 0.039	1.672TyrVal: 1.672 ± 0.031	0.414TyrTrp: 0.414 ± 0.016	0.782TyrTyr: 0.782 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4388 proteins (1455496 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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